[ { "uniprot_canonical_ac": "A0A0R4ILX9-1", "uniprot_id": [ { "id": "A0A0R4ILX9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILX9", "type": "external" } ], "mass": 21425.0, "length": 187, "protein_name": "V-set and transmembrane domain-containing protein 2-like protein", "gene_name": "vstm2lb", "organism": "Zebrafish", "refseq_name": "V-set and transmembrane domain-containing protein 2-like protein precursor", "refseq_ac": [ { "id": "NP_956790", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956790", "type": "external" } ], "gene_names_uniprotkb": "vstm2lb; vstm2l; zgc:66133", "gene_names_refseq": "vstm2lb; vstm2l; zgc:66133", "protein_names_uniprotkb": "V-set and transmembrane domain-containing protein 2-like protein", "protein_names_refseq": "V-set and transmembrane domain-containing protein 2-like protein precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:393468)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;35350973", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC044470.1, CU458955.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505371, SAMEA3505372 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Mar 13, 2018 this sequence version replaced NP_956790.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B050", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0043524 negative regulation of neuron apoptotic process;GO:0036268 swimming;GO:1902869 regulation of amacrine cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4ILX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IM04-1", "uniprot_id": [ { "id": "A0A0R4IM04_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IM04", "type": "external" } ], "mass": 37875.0, "length": 329, "protein_name": "Uncharacterized protein LOC324116; Uncharacterized protein isoform X1; Zgc:174696", "gene_name": "wu:fc19a12", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC324116", "refseq_ac": [ { "id": "NP_001108356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108356", "type": "external" } ], "gene_names_uniprotkb": "wu:fc19a12; fc19a12; zgc:174696", "gene_names_refseq": "fc19a12; wu:fc19a12; zgc:174696", "protein_names_uniprotkb": "Uncharacterized protein LOC324116; Uncharacterized protein isoform X1; Zgc:174696", "protein_names_refseq": "uncharacterized protein LOC324116", "tax_id": 7955, "disease": "", "pathway": " (dre:324116)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155246.1, SRR32588724.2276947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476743, SAMEA4476747 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jan 19, 2011 this sequence version replaced NP_001108356.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFX1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IM04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IM31-1", "uniprot_id": [ { "id": "ORA1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IM31", "type": "external" } ], "mass": 34498.0, "length": 316, "protein_name": "Olfactory receptor class A-like protein 1", "gene_name": "ora1", "organism": "Zebrafish", "refseq_name": "olfactory receptor class A-like protein 1", "refseq_ac": [ { "id": "NP_001124140", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001124140", "type": "external" } ], "gene_names_uniprotkb": "ora1; Vlr2", "gene_names_refseq": "ora1; vir2; vn1r1l; zgc:194316", "protein_names_uniprotkb": "Olfactory receptor class A-like protein 1; Vomeronasal type-1 receptor-like protein", "protein_names_refseq": "V1R2; V1r pheromone receptor-like; V1r-like homolog; olfactory receptor class A-like protein 1; vn1r2l; vomeronasal 1 receptor 1 like; vomeronasal type-1 receptor-like protein", "tax_id": 7955, "disease": "", "pathway": " (dre:553133)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15809442;17717047;23594743;24831010", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC163621.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC163621.1. On Mar 30, 2011 this sequence version replaced NP_001018340.1., [RefSeq]; 4-hydroxyphenylacetic acid might function as a pheromone for reproductive behavior in zebrafish. ORA1 is ancestral to mammalian V1Rs, [RefSeq, PubMed]; Probable pheromone receptor. Shows high specificity for 4-hydroxyphenylacetic acid. Activation of the receptor stimulates intracellular calcium release., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A8E0W7;B3DJV6;Q58QC6;Q597G5", "ec_number_list": [], "go_molecular_function": "GO:0005550 pheromone binding;GO:0016503 pheromone receptor activity;GO:0072545 L-tyrosine binding;GO:0033293 monocarboxylic acid binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007608 sensory perception of smell;GO:0019236 response to pheromone", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IM31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IM59-1", "uniprot_id": [ { "id": "A0A0R4IM59_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IM59", "type": "external" } ], "mass": 305592.0, "length": 2780, "protein_name": "Neural-cadherin; Si:dkey-22o22.2", "gene_name": "si:dkey-22o22.2", "organism": "Zebrafish", "refseq_name": "neural-cadherin isoform X1", "refseq_ac": [ { "id": "XP_001921123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921123", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-22o22.2", "gene_names_refseq": "si:dkey-22o22.2", "protein_names_uniprotkb": "Neural-cadherin; Si:dkey-22o22.2", "protein_names_refseq": "neural-cadherin isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100149950)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001921123.2. COMPLETENESS: full length., [RefSeq]; Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QQV6", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0007409 axonogenesis;GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0002009 morphogenesis of an epithelium;GO:0045216 cell-cell junction organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IM59-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IM72-1", "uniprot_id": [ { "id": "A0A0R4IM72_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IM72", "type": "external" } ], "mass": 32246.0, "length": 273, "protein_name": "Si:dkeyp-53d3.5; Uncharacterized protein LOC563210; Uncharacterized protein isoform X1", "gene_name": "si:dkeyp-53d3.5", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC563210", "refseq_ac": [ { "id": "NP_001038477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038477", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-53d3.5", "gene_names_refseq": "si:dkeyp-53d3.5", "protein_names_uniprotkb": "Si:dkeyp-53d3.5; Uncharacterized protein LOC563210; Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein LOC563210", "tax_id": 7955, "disease": "", "pathway": " (dre:563210)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH432845.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476761, SAMEA4476810 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH432845.1. On Sep 1, 2006 this sequence version replaced XP_691666.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9S4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IM72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IM91-1", "uniprot_id": [ { "id": "A0A0R4IM91_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IM91", "type": "external" } ], "mass": 105181.0, "length": 915, "protein_name": "Short transient receptor potential channel 4b isoform X1; Transient receptor potential cation channel, subfamily C, member 4b", "gene_name": "trpc4b", "organism": "Zebrafish", "refseq_name": "short transient receptor potential channel 4b isoform X1", "refseq_ac": [ { "id": "XP_009290061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290061", "type": "external" } ], "gene_names_uniprotkb": "trpc4b; trpc4a", "gene_names_refseq": "trpc4a; trpc4b", "protein_names_uniprotkb": "Short transient receptor potential channel 4b isoform X1; Transient receptor potential cation channel, subfamily C, member 4b", "protein_names_refseq": "short transient receptor potential channel 4b isoform X1", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); autism spectrum disorder (Disease Ontology:DOID:0060041); neurodegenerative disease (Disease Ontology:DOID:1289); lung cancer (Disease Ontology:DOID:1324)", "pathway": " (dre:102725536); (R-DRE-3295583)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "23594743;23943873;24038627;27773705;29717981;33186875;33236980", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AIN4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0005261 monoatomic cation channel activity;GO:0015279 store-operated calcium channel activity;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0034703 cation channel complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0051480 regulation of cytosolic calcium ion concentration;GO:0006812 monoatomic cation transport;GO:0070588 calcium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IM91-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMA9-1", "uniprot_id": [ { "id": "A0A0R4IMA9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMA9", "type": "external" } ], "mass": 49198.0, "length": 436, "protein_name": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1; EGF-like repeats and discoidin I-like domains 3a", "gene_name": "edil3a", "organism": "Zebrafish", "refseq_name": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1", "refseq_ac": [ { "id": "XP_001332616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001332616", "type": "external" } ], "gene_names_uniprotkb": "edil3a", "gene_names_refseq": "edil3a", "protein_names_uniprotkb": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1; EGF-like repeats and discoidin I-like domains 3a", "protein_names_refseq": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:793444)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_001332616.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PYP8", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0010811 positive regulation of cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMB2-1", "uniprot_id": [ { "id": "A0A0R4IMB2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMB2", "type": "external" } ], "mass": 182826.0, "length": 1642, "protein_name": "Complement C3a, tandem duplicate 6; Complement component c3a, duplicate 6 precursor", "gene_name": "c3a.6", "organism": "Zebrafish", "refseq_name": "complement component c3a, duplicate 6 precursor", "refseq_ac": [ { "id": "NP_001008582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008582", "type": "external" } ], "gene_names_uniprotkb": "c3a.6; zgc:103710; zgc:153510", "gene_names_refseq": "c3a.6; zgc:103710; zgc:153510", "protein_names_uniprotkb": "Complement C3a, tandem duplicate 6; Complement component c3a, duplicate 6 precursor", "protein_names_refseq": "c3.6; complement component c3a, duplicate 6 precursor; complement component c3a, duplicate 6", "tax_id": 7955, "disease": "paroxysmal nocturnal hemoglobinuria (Disease Ontology:DOID:0060284); lupus nephritis (Disease Ontology:DOID:0080162); atypical hemolytic-uremic syndrome (Disease Ontology:DOID:0080301); COVID-19 (Disease Ontology:DOID:0080600); erythema nodosum (Disease Ontology:DOID:0080750); age related macular degeneration 7 (Disease Ontology:DOID:0110019); age related macular degeneration 9 (Disease Ontology:DOID:0110021); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); dry eye syndrome (Disease Ontology:DOID:10140); silicosis (Disease Ontology:DOID:10325); Alzheimer's disease (Disease Ontology:DOID:10652); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); lepromatous leprosy (Disease Ontology:DOID:10887); sickle cell anemia (Disease Ontology:DOID:10923); adult respiratory distress syndrome (Disease Ontology:DOID:11394); Fuchs' endothelial dystrophy (Disease Ontology:DOID:11555); factor VIII deficiency (Disease Ontology:DOID:12134); pulmonary sarcoidosis (Disease Ontology:DOID:13406); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); anterior uveitis (Disease Ontology:DOID:1407); boutonneuse fever (Disease Ontology:DOID:14095); opiate dependence (Disease Ontology:DOID:2559); asthma (Disease Ontology:DOID:2841); membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); pulmonary tuberculosis (Disease Ontology:DOID:2957); IgA glomerulonephritis (Disease Ontology:DOID:2986); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321); atopic dermatitis (Disease Ontology:DOID:3310); mood disorder (Disease Ontology:DOID:3324); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); rhinitis (Disease Ontology:DOID:4483); arteriolosclerosis (Disease Ontology:DOID:5162); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); conjunctivitis (Disease Ontology:DOID:6195); rheumatoid arthritis (Disease Ontology:DOID:7148); complement component 3 deficiency (Disease Ontology:DOID:8354); systemic lupus erythematosus (Disease Ontology:DOID:9074); ocular hypertension (Disease Ontology:DOID:9282); acute myocardial infarction (Disease Ontology:DOID:9408); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dre:494039); (R-DRE-173736); (R-DRE-174577); (R-DRE-375276); (R-DRE-381426); (R-DRE-418594); (R-DRE-6798695); (R-DRE-8957275); (R-DRE-977606)", "pathway_count": 9, "publication_count": 11, "publication_id_list": "22805612;23594743;24926798;26469318;27375187;29883909;30547092;32973200;35748539;36736605;37489330", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505374, SAMEA3505377 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1 and DT079025.1. On Nov 26, 2014 this sequence version replaced NP_001008582.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 42, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N3I8", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IMB2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMF1-1", "uniprot_id": [ { "id": "A0A0R4IMF1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMF1", "type": "external" } ], "mass": 27173.0, "length": 246, "protein_name": "Ankyrin repeat domain-containing protein 53 isoform X1; Si:ch211-1o7.2", "gene_name": "ankrd53", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ankrd53", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 53 isoform X1; Si:ch211-1o7.2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UV80", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:1902412 regulation of mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMF1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMF6-1", "uniprot_id": [ { "id": "A0A0R4IMF6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMF6", "type": "external" } ], "mass": 69413.0, "length": 616, "protein_name": "Eukaryotic translation initiation factor 4B", "gene_name": "eif4ba", "organism": "Zebrafish", "refseq_name": "eukaryotic translation initiation factor 4Ba", "refseq_ac": [ { "id": "NP_001092707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092707", "type": "external" } ], "gene_names_uniprotkb": "eif4ba; eif4b", "gene_names_refseq": "eif4ba; eif4b", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4B", "protein_names_refseq": "eukaryotic translation initiation factor 4Ba; eukaryotic translation initiation factor 4B", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); major depressive disorder (Disease Ontology:DOID:1470)", "pathway": " (dre:553214); (R-DRE-156827); (R-DRE-166208); (R-DRE-72649); (R-DRE-72662); (R-DRE-72702)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "23594743;30319547;34749643", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC129148.1, GFIL01009497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001092707.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NDT4", "ec_number_list": [], "go_molecular_function": "GO:0043024 ribosomal small subunit binding;GO:0003743 translation initiation factor activity;GO:0034057 RNA strand-exchange activity;GO:0033592 RNA strand annealing activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0097010 eukaryotic translation initiation factor 4F complex assembly;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IMF6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMG2-1", "uniprot_id": [ { "id": "A0A0R4IMG2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMG2", "type": "external" } ], "mass": 57098.0, "length": 507, "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "gnsb", "organism": "Zebrafish", "refseq_name": "glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b precursor", "refseq_ac": [ { "id": "NP_956135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956135", "type": "external" } ], "gene_names_uniprotkb": "gnsb; gns; wu:fi20h10; zgc:55370", "gene_names_refseq": "", "protein_names_uniprotkb": "N-acetylglucosamine-6-sulfatase; 3.1.6.14; Glucosamine-6-sulfatase", "protein_names_refseq": "", "tax_id": 7955, "disease": "mucopolysaccharidosis type IIID (Disease Ontology:DOID:0111402); mucopolysaccharidosis III (Disease Ontology:DOID:12801)", "pathway": " (dre:327635)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11116086;16109975;23594743;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC045323.1, GDQH01000390.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On or before Feb 25, 2016 this sequence version replaced XP_005155531.1, NP_956135.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and orthologous alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PFZ3", "ec_number_list": [], "go_molecular_function": "GO:0008449 N-acetylglucosamine-6-sulfatase activity;GO:0046872 metal ion binding;GO:0005539 glycosaminoglycan binding", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "GO:0030203 glycosaminoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IMG2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMG3-1", "uniprot_id": [ { "id": "A0A0R4IMG3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMG3", "type": "external" } ], "mass": 23583.0, "length": 205, "protein_name": "Protein THEM6", "gene_name": "them6", "organism": "Zebrafish", "refseq_name": "Protein THEM6-like", "refseq_ac": [ { "id": "NP_001116176", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116176", "type": "external" } ], "gene_names_uniprotkb": "them6; si:ch73-52e5.1; wu:fb81b06", "gene_names_refseq": "si:ch73-52e5.1; them6; wu:fb81b06", "protein_names_uniprotkb": "Protein THEM6", "protein_names_refseq": "Protein THEM6-like", "tax_id": 7955, "disease": "", "pathway": " (dre:569944)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124728.1, EH553650.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476769, SAMEA4476784 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On Mar 17, 2008 this sequence version replaced XP_698454.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NI46", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IMG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMG9-1", "uniprot_id": [ { "id": "A0A0R4IMG9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMG9", "type": "external" } ], "mass": 39093.0, "length": 333, "protein_name": "Small nuclear ribonucleoprotein 48 (U11/U12); U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "gene_name": "snrnp48", "organism": "Zebrafish", "refseq_name": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "refseq_ac": [ { "id": "NP_001108614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108614", "type": "external" } ], "gene_names_uniprotkb": "snrnp48; fd10a06; wu:fd10a06", "gene_names_refseq": "fd10a06; snrnp48; wu:fd10a06", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein 48 (U11/U12); U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "protein_names_refseq": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "tax_id": 7955, "disease": "", "pathway": " (dre:325757)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16109975;23594743;29872546", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588721.3158493.1, SRR26395015.328131.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000016.1. On Mar 7, 2008 this sequence version replaced XP_699615.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NI61", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:1990904 ribonucleoprotein complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IMG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMH6-1", "uniprot_id": [ { "id": "A0A0R4IMH6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMH6", "type": "external" } ], "mass": 10334.0, "length": 90, "protein_name": "Si:dkey-65b13.8; Uncharacterized protein LOC561480", "gene_name": "si:dkey-65b13.8", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:dkey-65b13.8", "gene_names_refseq": "", "protein_names_uniprotkb": "Si:dkey-65b13.8; Uncharacterized protein LOC561480", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:561480)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9W0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMI8-1", "uniprot_id": [ { "id": "A0A0R4IMI8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMI8", "type": "external" } ], "mass": 37102.0, "length": 322, "protein_name": "Protein kinase-like domain-containing; Uncharacterized protein pkdc", "gene_name": "pkdc", "organism": "Zebrafish", "refseq_name": "uncharacterized protein pkdc", "refseq_ac": [ { "id": "XP_001335286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001335286", "type": "external" } ], "gene_names_uniprotkb": "pkdc", "gene_names_refseq": "pkdc", "protein_names_uniprotkb": "Protein kinase-like domain-containing; Uncharacterized protein pkdc", "protein_names_refseq": "uncharacterized protein pkdc", "tax_id": 7955, "disease": "", "pathway": " (dre:797003)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PS16", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMI8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMJ9-1", "uniprot_id": [ { "id": "A0A0R4IMJ9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMJ9", "type": "external" } ], "mass": 51049.0, "length": 450, "protein_name": "NEDD4-binding protein 2-like 2", "gene_name": "n4bp2l2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein n4bp2l2", "refseq_ac": [ { "id": "XP_693749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693749", "type": "external" } ], "gene_names_uniprotkb": "n4bp2l2", "gene_names_refseq": "n4bp2l2", "protein_names_uniprotkb": "NEDD4-binding protein 2-like 2", "protein_names_refseq": "uncharacterized protein n4bp2l2", "tax_id": 7955, "disease": "", "pathway": " (dre:565380)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_693749.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7I7", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMM1-1", "uniprot_id": [ { "id": "A0A0R4IMM1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMM1", "type": "external" } ], "mass": 67900.0, "length": 626, "protein_name": "Uncharacterized protein LOC100136863 precursor; Zgc:175136", "gene_name": "zgc:175136", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100136863 precursor", "refseq_ac": [ { "id": "NP_001108053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108053", "type": "external" } ], "gene_names_uniprotkb": "zgc:175136", "gene_names_refseq": "zgc:175136", "protein_names_uniprotkb": "Uncharacterized protein LOC100136863 precursor; Zgc:175136", "protein_names_refseq": "uncharacterized protein LOC100136863 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100136863)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155838.1, GFIL01046664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On or before Jun 26, 2024 this sequence version replaced XP_005173828.1, NP_001108053.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BL21", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IMM1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMN7-1", "uniprot_id": [ { "id": "A0A0R4IMN7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMN7", "type": "external" } ], "mass": 42703.0, "length": 372, "protein_name": "Uncharacterized protein LOC445160; Zgc:101130", "gene_name": "zgc:101130", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC445160", "refseq_ac": [ { "id": "NP_001037792", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001037792", "type": "external" } ], "gene_names_uniprotkb": "zgc:101130", "gene_names_refseq": "zgc:101130", "protein_names_uniprotkb": "Uncharacterized protein LOC445160; Zgc:101130", "protein_names_refseq": "uncharacterized protein LOC445160; zinc finger protein 300-like", "tax_id": 7955, "disease": "", "pathway": " (dre:445160)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15520368;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC134101.1, GDQH01023805.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On or before Apr 17, 2008 this sequence version replaced NP_001003554.1, XP_701452.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N959", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IMN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMS9-1", "uniprot_id": [ { "id": "A0A0R4IMS9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMS9", "type": "external" } ], "mass": 216818.0, "length": 1965, "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "polr2a", "organism": "Zebrafish", "refseq_name": "DNA-directed RNA polymerase II subunit RPB1", "refseq_ac": [ { "id": "XP_005156282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156282", "type": "external" } ], "gene_names_uniprotkb": "polr2a", "gene_names_refseq": "polr2a", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB1", "tax_id": 7955, "disease": "", "pathway": " (dre:553347); (R-DRE-113418); (R-DRE-674695); (R-DRE-6781823); (R-DRE-6782135); (R-DRE-6782210); (R-DRE-6796648); (R-DRE-6803529); (R-DRE-6807505); (R-DRE-72086); (R-DRE-72163); (R-DRE-72165); (R-DRE-72203); (R-DRE-73776); (R-DRE-73779); (R-DRE-75953); (R-DRE-75955); (R-DRE-76042); (R-DRE-77075); (R-DRE-9018519); (R-DRE-9770562)", "pathway_count": 21, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]; RNA-dependent RNA polymerase that catalyzes the extension of a non-coding RNA (ncRNA) at the 3'-end using the four ribonucleoside triphosphates as substrates. An internal ncRNA sequence near the 3'-end serves as a template in a single-round Pol II-mediated RNA polymerization reaction. May decrease the stability of ncRNAs that repress Pol II-mediated gene transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B2W1", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.1.1.348", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.348", "type": "external" }, { "id": "2.1.1.56", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.56", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" } ], "go_molecular_function": "GO:0003968 RNA-directed RNA polymerase activity;GO:0003677 DNA binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0042789 mRNA transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMS9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMW2-1", "uniprot_id": [ { "id": "A0A0R4IMW2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMW2", "type": "external" } ], "mass": 25044.0, "length": 225, "protein_name": "Methyltransferase-like 23; Methyltransferase-like protein 23", "gene_name": "mettl23", "organism": "Zebrafish", "refseq_name": "histone-arginine methyltransferase METTL23", "refseq_ac": [ { "id": "NP_001314968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314968", "type": "external" } ], "gene_names_uniprotkb": "mettl23; ik:tdsubc_1b12; si:ch73-366l1.2; xx:tdsubc_1b12", "gene_names_refseq": "ik:tdsubc_1b12; mettl23; si:ch73-366l1.2; xx:tdsubc_1b12", "protein_names_uniprotkb": "Methyltransferase-like 23; Methyltransferase-like protein 23", "protein_names_refseq": "histone-arginine methyltransferase METTL23; methyltransferase like 23", "tax_id": 7955, "disease": "autosomal recessive intellectual developmental disorder 44 (Disease Ontology:DOID:0081208); glaucoma (Disease Ontology:DOID:1686)", "pathway": " (dre:337849)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01013214.1, SRR26395015.171374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1, EH544735.1, EH552856.1 and EH563165.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9S6", "ec_number_list": [], "go_molecular_function": "GO:0035642 histone H3R17 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0040029 epigenetic regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IMW2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMY5-1", "uniprot_id": [ { "id": "A0A0R4IMY5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMY5", "type": "external" } ], "mass": 43229.0, "length": 387, "protein_name": "Testican-2", "gene_name": "spock3", "organism": "Zebrafish", "refseq_name": "testican-3 isoform a precursor", "refseq_ac": [ { "id": "NP_001314916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314916", "type": "external" } ], "gene_names_uniprotkb": "spock3; im:7139568; si:dkey-285b22.1", "gene_names_refseq": "im:7139568; si:dkey-285b22.1; spock3", "protein_names_uniprotkb": "Testican-2; SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2", "protein_names_refseq": "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3; testican 3; testican-3 isoform a precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:562002)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16545530;19308258;23594743;32430393;36127326", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC153904.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1, EH433753.1, EB939186.1, EH447295.1, EH458122.1 and EH468737.1. On Jun 1, 2016 this sequence version replaced XP_690495.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; May participate in diverse steps of neurogenesis. Binds calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8M2", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IMY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMY7-1", "uniprot_id": [ { "id": "TRPM2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMY7", "type": "external" } ], "mass": 167987.0, "length": 1470, "protein_name": "Transient receptor potential cation channel subfamily M member 2", "gene_name": "trpm2", "organism": "Zebrafish", "refseq_name": "transient receptor potential cation channel subfamily M member 2", "refseq_ac": [ { "id": "NP_001275746", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001275746", "type": "external" } ], "gene_names_uniprotkb": "trpm2; si:ch73-263b18.1", "gene_names_refseq": "si:ch73-263b18.1; trpm2", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily M member 2", "protein_names_refseq": "transient receptor potential cation channel subfamily M member 2; transient receptor potential melastatin 2", "tax_id": 7955, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (dre:799412); (R-DRE-3295583); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "23594743;23908157;30250252;33924946", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KF305307.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KF305307.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Nonselective, voltage-independent cation channel that mediates Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels. Functions as a ligand-gated ion channel, gated by intracellular adenosine diphosphate ribose (ADP-ribose), Ca(2+), warm temperature, and oxidative stress (PubMed:30250252). Binding of ADP-ribose to the cytoplasmic N-terminal region causes a conformation change; the channel is primed but still requires Ca(2+) binding to trigger channel opening (PubMed:30250252)., [UniProtKB, PubMed]; Species-Specific Regulation of TRPM2 by PI(4,5)P2 via the Membrane Interfacial Cavity. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IF00;S5TZ89", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005216 monoatomic ion channel activity;GO:0005262 calcium channel activity;GO:0005509 calcium ion binding;GO:0072570 ADP-D-ribose binding;GO:0099604 ligand-gated calcium channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0070588 calcium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IMY7-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.0000000000000001.0000000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMZ6-1", "uniprot_id": [ { "id": "A0A0R4IMZ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMZ6", "type": "external" } ], "mass": 19442.0, "length": 173, "protein_name": "Extracellular matrix protein 1", "gene_name": "ecm1a", "organism": "Zebrafish", "refseq_name": "extracellular matrix protein 1", "refseq_ac": [ { "id": "XP_003200603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200603", "type": "external" } ], "gene_names_uniprotkb": "ecm1a", "gene_names_refseq": "ecm1a", "protein_names_uniprotkb": "Extracellular matrix protein 1", "protein_names_refseq": "extracellular matrix protein 1", "tax_id": 7955, "disease": "lipoid proteinosis (Disease Ontology:DOID:14498)", "pathway": " (dre:100536787)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RP16", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IMZ6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMZ7-1", "uniprot_id": [ { "id": "A0A0R4IMZ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMZ7", "type": "external" } ], "mass": 36050.0, "length": 315, "protein_name": "[histone H4]-lysine(20) N-methyltransferase", "gene_name": "kmt5ab", "organism": "Zebrafish", "refseq_name": "lysine methyltransferase 5Ab", "refseq_ac": [ { "id": "NP_001093559", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093559", "type": "external" } ], "gene_names_uniprotkb": "kmt5ab; setd8b; wu:fc23f12; zgc:171649", "gene_names_refseq": "kmt5ab; setd8b; wu:fc23f12; zgc:171649", "protein_names_uniprotkb": "[histone H4]-lysine(20) N-methyltransferase; 2.1.1.361", "protein_names_refseq": "SET domain containing (lysine methyltransferase) 8b; SET domain containing 8b; lysine methyltransferase 5Ab", "tax_id": 7955, "disease": "", "pathway": " (dre:100004770)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "18231586;23594743;24174574;24240475;26972483;31078877;36846912", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC151909.1, GDQH01026878.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001093559.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFD5", "ec_number_list": [ { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" } ], "go_molecular_function": "GO:0042799 histone H4K20 methyltransferase activity;GO:0140944 histone H4K20 monomethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005700 polytene chromosome", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IMZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IMZ8-1", "uniprot_id": [ { "id": "A0A0R4IMZ8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IMZ8", "type": "external" } ], "mass": 97467.0, "length": 876, "protein_name": "Importin subunit beta-1; Karyopherin (importin) beta 1", "gene_name": "kpnb1", "organism": "Zebrafish", "refseq_name": "importin subunit beta-1", "refseq_ac": [ { "id": "NP_001032791", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032791", "type": "external" } ], "gene_names_uniprotkb": "kpnb1; wu:fc12b10; zgc:123184", "gene_names_refseq": "kpnb1; wu:fc12b10; zgc:123184", "protein_names_uniprotkb": "Importin subunit beta-1; Karyopherin (importin) beta 1", "protein_names_refseq": "importin subunit beta-1; karyopherin beta 1", "tax_id": 7955, "disease": "", "pathway": " (dre:570700); (R-DRE-140342); (R-DRE-1655829); (R-DRE-2995383); (R-DRE-6798695); (R-DRE-68616); (R-DRE-909733)", "pathway_count": 7, "publication_count": 7, "publication_id_list": "16109975;16616005;18086703;23594743;26553237;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01002210.1, SRR32588715.1879154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Nov 19, 2014 this sequence version replaced NP_001032791.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N881", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0008139 nuclear localization sequence binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm", "go_biological_process": "GO:0048513 animal organ development;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IMZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN12-1", "uniprot_id": [ { "id": "A0A0R4IN12_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN12", "type": "external" } ], "mass": 8365.0, "length": 76, "protein_name": "Ovomucoid; Serine peptidase inhibitor, Kazal type 2, tandem duplicate 4", "gene_name": "spink2.4", "organism": "Zebrafish", "refseq_name": "ovomucoid", "refseq_ac": [ { "id": "XP_003199924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199924", "type": "external" } ], "gene_names_uniprotkb": "spink2.4", "gene_names_refseq": "spink2.4", "protein_names_uniprotkb": "Ovomucoid; Serine peptidase inhibitor, Kazal type 2, tandem duplicate 4", "protein_names_refseq": "ovomucoid", "tax_id": 7955, "disease": "spermatogenic failure 29 (Disease Ontology:DOID:0111930)", "pathway": " (dre:100537980)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RMG9", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IN12-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN13-1", "uniprot_id": [ { "id": "A0A0R4IN13_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN13", "type": "external" } ], "mass": 10741.0, "length": 96, "protein_name": "Si:ch211-227e10.6; Uncharacterized protein LOC100008037", "gene_name": "si:ch211-227e10.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100008037", "refseq_ac": [ { "id": "NP_001121772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121772", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-227e10.6", "gene_names_refseq": "si:ch211-227e10.6", "protein_names_uniprotkb": "Si:ch211-227e10.6; Uncharacterized protein LOC100008037", "protein_names_refseq": "uncharacterized protein LOC100008037", "tax_id": 7955, "disease": "", "pathway": " (dre:100008037)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588734.1135312.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000004.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NH83", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IN13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN14-1", "uniprot_id": [ { "id": "A0A0R4IN14_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN14", "type": "external" } ], "mass": 72355.0, "length": 643, "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "raf1a", "organism": "Zebrafish", "refseq_name": "Raf-1 proto-oncogene, serine/threonine kinase a", "refseq_ac": [ { "id": "NP_571514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571514", "type": "external" } ], "gene_names_uniprotkb": "raf1a; c-raf; craf; raf1", "gene_names_refseq": "c-raf; craf; raf1a; raf1", "protein_names_uniprotkb": "RAF proto-oncogene serine/threonine-protein kinase; 2.7.11.1; Raf-1", "protein_names_refseq": "Raf-1 proto-oncogene, serine/threonine kinase a; serine/threonine protein kinase RAF1; v-raf-1 murine leukemia viral oncogene homolog 1a; v-raf-1 murine leukemia viral oncogene homolog 1", "tax_id": 7955, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); Noonan syndrome 5 (Disease Ontology:DOID:0060583); Noonan syndrome with multiple lentigines 2 (Disease Ontology:DOID:0080549); dilated cardiomyopathy 1NN (Disease Ontology:DOID:0110432); prostate cancer (Disease Ontology:DOID:10283); prostate adenocarcinoma (Disease Ontology:DOID:2526); Noonan syndrome (Disease Ontology:DOID:3490); pancreatic adenocarcinoma (Disease Ontology:DOID:4074)", "pathway": " (dre:30716); (R-DRE-392517); (R-DRE-430116); (R-DRE-5621575); (R-DRE-5673000); (R-DRE-5674135); (R-DRE-5674499); (R-DRE-5675221); (R-DRE-9732724)", "pathway_count": 9, "publication_count": 11, "publication_id_list": "10207156;12925535;16109975;17397257;17603482;23594743;27356472;27895053;28791256;31263281;33279959", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AB098700.1, GFIL01032163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476745, SAMEA4476762 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 26, 2015 this sequence version replaced NP_571514.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Zebrafish embryos with morpholino knockdown of raf1 demonstrated the need for raf1 for the development of normal myocardial structure and function., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P820", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004709 MAP kinase kinase kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0007507 heart development;GO:0000165 MAPK cascade;GO:0043408 regulation of MAPK cascade;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IN14-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN28-1", "uniprot_id": [ { "id": "A0A0R4IN28_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN28", "type": "external" } ], "mass": 214530.0, "length": 1969, "protein_name": "Ankyrin-1", "gene_name": "ank1a", "organism": "Zebrafish", "refseq_name": "ankyrin-1a isoform 1", "refseq_ac": [ { "id": "NP_001314819", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314819", "type": "external" } ], "gene_names_uniprotkb": "ank1a; ank1; si:ch211-173b16.3; wu:fa09h06; zgc:101835", "gene_names_refseq": "ank1a; ank1; si:ch211-173b16.3; wu:fa09h06; zgc:101835", "protein_names_uniprotkb": "Ankyrin-1; Erythrocyte ankyrin", "protein_names_refseq": "ankyrin-1a isoform 1", "tax_id": 7955, "disease": "hereditary spherocytosis type 1 (Disease Ontology:DOID:0110916); malaria (Disease Ontology:DOID:12365); hereditary spherocytosis (Disease Ontology:DOID:12971); transient cerebral ischemia (Disease Ontology:DOID:224); anemia (Disease Ontology:DOID:2355)", "pathway": " (dre:449796)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16109975;23594743;26015096;26469318;26963759;27189481;30309860;30837568", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001314819.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3X4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0014731 spectrin-associated cytoskeleton;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IN28-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN51-1", "uniprot_id": [ { "id": "A0A0R4IN51_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN51", "type": "external" } ], "mass": 176150.0, "length": 1545, "protein_name": "Si:rp71-1d10.8", "gene_name": "si:rp71-1d10.8", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:rp71-1d10.8", "refseq_ac": [ { "id": "XP_005173216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173216", "type": "external" } ], "gene_names_uniprotkb": "si:rp71-1d10.8", "gene_names_refseq": "si:rp71-1d10.8", "protein_names_uniprotkb": "Si:rp71-1d10.8", "protein_names_refseq": "uncharacterized protein si:rp71-1d10.8", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKG8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IN51-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN60-1", "uniprot_id": [ { "id": "A0A0R4IN60_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN60", "type": "external" } ], "mass": 22972.0, "length": 209, "protein_name": "Fibroblast growth factor", "gene_name": "fgf19", "organism": "Zebrafish", "refseq_name": "fibroblast growth factor 19 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001296288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296288", "type": "external" } ], "gene_names_uniprotkb": "fgf19", "gene_names_refseq": "fgf19", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 19 isoform 2 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:368245); (R-DRE-109704); (R-DRE-1257604); (R-DRE-1307965); (R-DRE-189200); (R-DRE-190322); (R-DRE-5654228); (R-DRE-5654712); (R-DRE-5654719); (R-DRE-5654720); (R-DRE-5654733); (R-DRE-5673001); (R-DRE-6811558)", "pathway_count": 13, "publication_count": 12, "publication_id_list": "12792807;16256099;17000708;18041922;18089288;23594743;31220433;31545209;32597709;33675223;34301599;36841347", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH498287.1, BC162870.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1 and EH498287.1. On May 27, 2015 this sequence version replaced XP_005166648.1. Transcript Variant: This variant (2) uses an alternate splice site in its 5' terminal exon and initiates translation from an alternate upstream start codon, compared to variant 1. The encoded isoform (2) has a longer N-terminus than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Fgf19 is required for zebrafish lens and retina development., [RefSeq, PubMed]; Fgf19 signaling is critical for embryonic forebrain development through its interaction with hedgehog., [RefSeq, PubMed]; This study reveals an important role for FOXC1 in the direct regulation of the FGF19-FGFR4-MAPK pathway to promote both the development and maintenance of anterior segment structures within the eye., [RefSeq, PubMed]; Thyroid Hormones Regulate Goblet Cell Differentiation and Fgf19-Fgfr4 Signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7M8", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0005104 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005576 extracellular region", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0007420 brain development;GO:0060041 retina development in camera-type eye;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0R4IN60-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN78-1", "uniprot_id": [ { "id": "A0A0R4IN78_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN78", "type": "external" } ], "mass": 48024.0, "length": 432, "protein_name": "Serine/threonine-protein kinase 24", "gene_name": "stk24b", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase 24 isoform X1", "refseq_ac": [ { "id": "XP_005165890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165890", "type": "external" } ], "gene_names_uniprotkb": "stk24b; stk24; wu:fi29b08; zgc:66137", "gene_names_refseq": "stk24b; stk24; wu:fi29b08; zgc:66137", "protein_names_uniprotkb": "Serine/threonine-protein kinase 24; 2.7.11.1; Mammalian STE20-like protein kinase 3; STE20-like kinase MST3", "protein_names_refseq": "serine/threonine-protein kinase 24 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:406786); (R-DRE-111465); (R-DRE-75153)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "20592472;23594743;26469318;28252024;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BD45", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.4.22.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.56", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0048679 regulation of axon regeneration;GO:0007507 heart development;GO:0035556 intracellular signal transduction;GO:0006915 apoptotic process;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IN78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IN87-1", "uniprot_id": [ { "id": "A0A0R4IN87_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IN87", "type": "external" } ], "mass": 82278.0, "length": 755, "protein_name": "GATA zinc finger domain containing 2Ab isoform X1; GATA zinc finger domain-containing 2Ab", "gene_name": "gatad2ab", "organism": "Zebrafish", "refseq_name": "GATA zinc finger domain containing 2Ab isoform X1", "refseq_ac": [ { "id": "XP_005170501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170501", "type": "external" } ], "gene_names_uniprotkb": "gatad2ab; gatad2a; ns:zf-a189; zgc:85938", "gene_names_refseq": "gatad2ab; gatad2a; ns:zf-a189; zgc:85938", "protein_names_uniprotkb": "GATA zinc finger domain containing 2Ab isoform X1; GATA zinc finger domain-containing 2Ab", "protein_names_refseq": "GATA zinc finger domain containing 2Ab isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:405852); (R-DRE-3214815); (R-DRE-6804758); (R-DRE-8943724)", "pathway_count": 4, "publication_count": 9, "publication_id_list": "15520368;16109975;23594743;26469318;26963759;27189481;30929901;40044042;9409775", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BHS7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0016581 NuRD complex;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IN87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INB9-1", "uniprot_id": [ { "id": "CX111_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INB9", "type": "external" } ], "mass": 10226.0, "length": 94, "protein_name": "C-X-C motif chemokine 11-1", "gene_name": "cxcl11.1", "organism": "Zebrafish", "refseq_name": "C-X-C motif chemokine 11-1 precursor", "refseq_ac": [ { "id": "NP_001373708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373708", "type": "external" } ], "gene_names_uniprotkb": "cxcl11.1; cxcl11aa", "gene_names_refseq": "cxcl11.1; cxcl11l", "protein_names_uniprotkb": "C-X-C motif chemokine 11-1", "protein_names_refseq": "C-X-C motif chemokine 11-1 precursor; C-X-C motif chemokine 11-1; CXCL-chr5d; CXCL11aa; chemokine (C-X-C motif) ligand 11 like; dr-chr5-CXCL11; vig7", "tax_id": 7955, "disease": "pulmonary sarcoidosis (Disease Ontology:DOID:13406); interstitial cystitis (Disease Ontology:DOID:13949); bronchiolitis obliterans (Disease Ontology:DOID:2799); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (dre:798892)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;25573892", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EB953258.1, SRR32588725.13374052.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Sep 3, 2020 this sequence version replaced XP_001339307.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006952 defense response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4INB9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INC3-1", "uniprot_id": [ { "id": "A0A0R4INC3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INC3", "type": "external" } ], "mass": 47754.0, "length": 432, "protein_name": "Transmembrane protease serine 4b; Transmembrane serine protease 4b", "gene_name": "tmprss4b", "organism": "Zebrafish", "refseq_name": "transmembrane protease serine 4b", "refseq_ac": [ { "id": "NP_001119849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119849", "type": "external" } ], "gene_names_uniprotkb": "tmprss4b; si:ch211-139a5.6; wu:fi21e09", "gene_names_refseq": "si:ch211-139a5.6; tmprss4b; wu:fi21e09", "protein_names_uniprotkb": "Transmembrane protease serine 4b; Transmembrane serine protease 4b", "protein_names_refseq": "transmembrane protease serine 4b; transmembrane protease, serine 4b", "tax_id": 7955, "disease": "", "pathway": " (dre:327651)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21657981;22922822;23594743;32969791", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC048135.1, SRR26395064.5525.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jul 31, 2008 this sequence version replaced XP_001332784.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1TS68", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4INC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INE3-1", "uniprot_id": [ { "id": "A0A0R4INE3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INE3", "type": "external" } ], "mass": 50184.0, "length": 426, "protein_name": "Endoplasmic reticulum protein SC65; Prolyl 3-hydroxylase family member 4 (inactive)", "gene_name": "p3h4", "organism": "Zebrafish", "refseq_name": "endoplasmic reticulum protein SC65 precursor", "refseq_ac": [ { "id": "NP_001119910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119910", "type": "external" } ], "gene_names_uniprotkb": "p3h4; fb75g07; leprel4; si:dkey-18f7.1; wu:fb75g07", "gene_names_refseq": "fb75g07; leprel4; p3h4; si:dkey-18f7.1; wu:fb75g07", "protein_names_uniprotkb": "Endoplasmic reticulum protein SC65; Prolyl 3-hydroxylase family member 4 (inactive)", "protein_names_refseq": "endoplasmic reticulum protein SC65 precursor; leprecan-like 4; prolyl 3-hydroxylase family member 4 (non-enzymatic)", "tax_id": 7955, "disease": "", "pathway": " (dre:570779)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01014361.1, SRR32588731.2063174.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Jul 31, 2008 this sequence version replaced XP_699389.3., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NJF3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4INE3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ING6-1", "uniprot_id": [ { "id": "A0A0R4ING6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ING6", "type": "external" } ], "mass": 28034.0, "length": 253, "protein_name": "Guided entry of tail-anchored proteins factor", "gene_name": "camlg", "organism": "Zebrafish", "refseq_name": "guided entry of tail-anchored proteins factor CAMLG", "refseq_ac": [ { "id": "NP_996973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996973", "type": "external" } ], "gene_names_uniprotkb": "camlg; zgc:77424", "gene_names_refseq": "camlg; zgc:77424", "protein_names_uniprotkb": "Guided entry of tail-anchored proteins factor; Calcium signal-modulating cyclophilin ligand", "protein_names_refseq": "guided entry of tail-anchored proteins factor CAMLG", "tax_id": 7955, "disease": "congenital disorder of glycosylation type IIz (Disease Ontology:DOID:0051053); myeloid leukemia (Disease Ontology:DOID:8692)", "pathway": " (dre:404622)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;28934490", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.977452.1, SRR26395028.1278902.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Oct 2, 2012 this sequence version replaced NP_996973.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PHG7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0043529 GET complex", "go_biological_process": "GO:0071816 tail-anchored membrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ING6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INH3-1", "uniprot_id": [ { "id": "A0A0R4INH3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INH3", "type": "external" } ], "mass": 101560.0, "length": 922, "protein_name": "INO80 complex subunit Da", "gene_name": "ino80da", "organism": "Zebrafish", "refseq_name": "INO80 complex subunit Da", "refseq_ac": [ { "id": "NP_001410255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410255", "type": "external" } ], "gene_names_uniprotkb": "ino80da; si:ch73-357e20.1", "gene_names_refseq": "ino80da; si:ch73-357e20.1", "protein_names_uniprotkb": "INO80 complex subunit Da", "protein_names_refseq": "INO80 complex subunit D-like; INO80 complex subunit Da", "tax_id": 7955, "disease": "", "pathway": " (dre:110440037); (R-DRE-5689603); (R-DRE-5696394)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "21873635;23594743;32196499", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.1033791.1, GFIL01022706.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Jul 14, 2023 this sequence version replaced XP_021334490.1., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QJX9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4INH3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INJ4-1", "uniprot_id": [ { "id": "A0A0R4INJ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INJ4", "type": "external" } ], "mass": 63099.0, "length": 551, "protein_name": "FinTRIM family, member 64", "gene_name": "ftr64", "organism": "Zebrafish", "refseq_name": "finTRIM family, member 64", "refseq_ac": [ { "id": "NP_001314743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314743", "type": "external" } ], "gene_names_uniprotkb": "ftr64; ftr56", "gene_names_refseq": "ftr56; ftr64", "protein_names_uniprotkb": "FinTRIM family, member 64", "protein_names_refseq": "finTRIM family, member 64", "tax_id": 7955, "disease": "", "pathway": " (dre:562311); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "19196451;21789205;23594743;30550990", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AM941321.1, GDQQ01004622.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On May 26, 2016 this sequence version replaced XP_002661885.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P924", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4INJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INK2-1", "uniprot_id": [ { "id": "A0A0R4INK2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INK2", "type": "external" } ], "mass": 58072.0, "length": 518, "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase", "gene_name": "uap1", "organism": "Zebrafish", "refseq_name": "UDP-N-acetylhexosamine pyrophosphorylase isoform 1", "refseq_ac": [ { "id": "NP_001352191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352191", "type": "external" } ], "gene_names_uniprotkb": "uap1; fb63d12; wu:fb63d12; zgc:55280", "gene_names_refseq": "fb63d12; uap1; wu:fb63d12; zgc:55280", "protein_names_uniprotkb": "UDP-N-acetylhexosamine pyrophosphorylase; 2.7.7.23; 2.7.7.83; Protein-pyrophosphorylation enzyme; UDP-N-acetylgalactosamine pyrophosphorylase; UDP-N-acetylglucosamine pyrophosphorylase", "protein_names_refseq": "UDP-N-acetylhexosamine pyrophosphorylase isoform 1; UDP-N-acteylglucosamine pyrophosphorylase 1", "tax_id": 7955, "disease": "", "pathway": " (dre:322513); (R-DRE-446210)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "16109975;21925157;23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01042451.1, SRR32588726.36065522.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505391, SAMEA3505392 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On or before Aug 11, 2018 this sequence version replaced XP_021332457.1, XP_005166312.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Isoform AGX1 has 2 to 3 times higher activity towards galactosamine 1-phosphate (GalNAc-1-P)., [UniProtKB, UniProtKB]; Isoform AGX2 has 8 times more activity towards glucosamine 1-phosphate (GlcNAc-1-P)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PLV6", "ec_number_list": [ { "id": "2.7.7.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.23", "type": "external" }, { "id": "2.7.7.83", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.83", "type": "external" } ], "go_molecular_function": "GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity;GO:0052630 UDP-N-acetylgalactosamine diphosphorylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045087 innate immune response;GO:0006048 UDP-N-acetylglucosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4INK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INM0-1", "uniprot_id": [ { "id": "A0A0R4INM0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INM0", "type": "external" } ], "mass": 162967.0, "length": 1440, "protein_name": "Macrophage mannose receptor 1", "gene_name": "mrc1a", "organism": "Zebrafish", "refseq_name": "macrophage mannose receptor 1", "refseq_ac": [ { "id": "XP_002663014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663014", "type": "external" } ], "gene_names_uniprotkb": "mrc1a", "gene_names_refseq": "mrc1a", "protein_names_uniprotkb": "Macrophage mannose receptor 1", "protein_names_refseq": "macrophage mannose receptor 1", "tax_id": 7955, "disease": "", "pathway": " (dre:100286774); (R-DRE-1236978)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002663014.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RLY6", "ec_number_list": [], "go_molecular_function": "GO:0005537 D-mannose binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4INM0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INS8-1", "uniprot_id": [ { "id": "A0A0R4INS8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INS8", "type": "external" } ], "mass": 18808.0, "length": 165, "protein_name": "Retinoic acid receptor responder 3", "gene_name": "rarres3", "organism": "Zebrafish", "refseq_name": "retinoic acid receptor responder 3", "refseq_ac": [ { "id": "NP_001070094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070094", "type": "external" } ], "gene_names_uniprotkb": "rarres3; zgc:154040", "gene_names_refseq": "rarres3; zgc:154040", "protein_names_uniprotkb": "Retinoic acid receptor responder 3", "protein_names_refseq": "retinoic acid receptor responder 3", "tax_id": 7955, "disease": "", "pathway": " (dre:767688); (R-DRE-1482839)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "23594743;24683187;26469318;33854238", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH501496.1, BC124520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH501496.1, CK027983.1, EH525615.1 and EH518500.1. On Jun 17, 2015 this sequence version replaced NP_001070094.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NAZ5", "ec_number_list": [], "go_molecular_function": "GO:0004623 phospholipase A2 activity;GO:0008970 phospholipase A1 activity;GO:0016410 N-acyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0070292 N-acylphosphatidylethanolamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4INS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INT7-1", "uniprot_id": [ { "id": "A0A0R4INT7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INT7", "type": "external" } ], "mass": 40680.0, "length": 360, "protein_name": "Homer protein homolog 1", "gene_name": "homer1b", "organism": "Zebrafish", "refseq_name": "homer protein homolog 1b isoform 2", "refseq_ac": [ { "id": "NP_001313219", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313219", "type": "external" } ], "gene_names_uniprotkb": "homer1b; homer1; zgc:100854; zgc:92844", "gene_names_refseq": "homer1b; homer1; zgc:100854; zgc:92844", "protein_names_uniprotkb": "Homer protein homolog 1", "protein_names_refseq": "homer homolog 1b; homer homolog 1; homer protein homolog 1b isoform 2; homer scaffolding protein 1b", "tax_id": 7955, "disease": "cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dre:436769); (R-DRE-6794361)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "23594743;23936160;24002024;27189481;28252024;29201571;32179471;33200539;35754711;35877057;36613611", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588726.5948031.1, SRR32588733.2817736.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On May 13, 2016 this sequence version replaced XP_005157352.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Results indicate that miR-3906 controls [Ca(2+)]i homeostasis in fast muscle through fine tuning homer-1b expression during differentiation Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2K2", "ec_number_list": [], "go_molecular_function": "GO:0035256 G protein-coupled glutamate receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0030425 dendrite", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0051966 regulation of synaptic transmission, glutamatergic;GO:2001256 regulation of store-operated calcium entry;GO:0061061 muscle structure development;GO:0007216 G protein-coupled glutamate receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4INT7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INZ0-1", "uniprot_id": [ { "id": "A0A0R4INZ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INZ0", "type": "external" } ], "mass": 20576.0, "length": 183, "protein_name": "Si:dkey-228b2.6; Uncharacterized protein LOC563918", "gene_name": "si:dkey-228b2.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC563918", "refseq_ac": [ { "id": "NP_001373166", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373166", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-228b2.6", "gene_names_refseq": "si:dkey-228b2.6", "protein_names_uniprotkb": "Si:dkey-228b2.6; Uncharacterized protein LOC563918", "protein_names_refseq": "uncharacterized protein LOC563918", "tax_id": 7955, "disease": "", "pathway": " (dre:563918)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122125.1, CN013906.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 15, 2020 this sequence version replaced XP_005161156.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B811", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4INZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INZ3-1", "uniprot_id": [ { "id": "A0A0R4INZ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INZ3", "type": "external" } ], "mass": 53804.0, "length": 494, "protein_name": "Solute carrier family 41 member", "gene_name": "slc41a2a", "organism": "Zebrafish", "refseq_name": "solute carrier family 41 member 2", "refseq_ac": [ { "id": "XP_693342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693342", "type": "external" } ], "gene_names_uniprotkb": "slc41a2a", "gene_names_refseq": "slc41a2a", "protein_names_uniprotkb": "Solute carrier family 41 member", "protein_names_refseq": "solute carrier family 41 member 2", "tax_id": 7955, "disease": "", "pathway": " (dre:564932)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_693342.3. COMPLETENESS: full length., [RefSeq]; Acts as a magnesium transporter., [UniProtKB, UniProtKB]; Acts as a plasma-membrane magnesium transporter. Can also mediate the transport of other divalent metal cations in an order of Ba(2+) > Ni(2+) > Co(2+) > Fe(2+) > Mn(2+)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TBE2", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0008324 monoatomic cation transmembrane transporter activity;GO:0022890 inorganic cation transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030001 metal ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4INZ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INZ4-1", "uniprot_id": [ { "id": "A0A0R4INZ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INZ4", "type": "external" } ], "mass": 35621.0, "length": 321, "protein_name": "Calcium channel, voltage-dependent, gamma subunit 2b", "gene_name": "cacng2b", "organism": "Zebrafish", "refseq_name": "calcium channel, voltage-dependent, gamma subunit 2b", "refseq_ac": [ { "id": "NP_001186659", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186659", "type": "external" } ], "gene_names_uniprotkb": "cacng2b", "gene_names_refseq": "cacng2b", "protein_names_uniprotkb": "Calcium channel, voltage-dependent, gamma subunit 2b", "protein_names_refseq": "calcium channel, voltage-dependent, gamma subunit 2b", "tax_id": 7955, "disease": "autosomal dominant intellectual developmental disorder 10 (Disease Ontology:DOID:0070040)", "pathway": " (dre:569855)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26178704;30685453;34329618", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122119.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505390 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CABZ01090724.1 and CABZ01090726.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NVJ4", "ec_number_list": [], "go_molecular_function": "GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity", "go_cellular_component": "GO:0032281 AMPA glutamate receptor complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4INZ4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4INZ6-1", "uniprot_id": [ { "id": "A0A0R4INZ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4INZ6", "type": "external" } ], "mass": 20325.0, "length": 178, "protein_name": "Probetacellulin", "gene_name": "btc", "organism": "Zebrafish", "refseq_name": "probetacellulin precursor", "refseq_ac": [ { "id": "NP_001038229", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038229", "type": "external" } ], "gene_names_uniprotkb": "btc", "gene_names_refseq": "btc", "protein_names_uniprotkb": "Probetacellulin", "protein_names_refseq": "betacellulin-like; probetacellulin precursor", "tax_id": 7955, "disease": "otitis media (Disease Ontology:DOID:10754); insulinoma (Disease Ontology:DOID:3892); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dre:503869); (R-DRE-1227986); (R-DRE-1236394); (R-DRE-1250196); (R-DRE-1250342); (R-DRE-1250347); (R-DRE-1257604); (R-DRE-177929); (R-DRE-179812); (R-DRE-180292); (R-DRE-180336); (R-DRE-182971); (R-DRE-1963640); (R-DRE-1963642); (R-DRE-212718); (R-DRE-5673001); (R-DRE-6785631); (R-DRE-6811558); (R-DRE-8847993); (R-DRE-8863795)", "pathway_count": 20, "publication_count": 11, "publication_id_list": "19000772;19799903;20105326;21909574;22138660;23594743;26469318;26599586;27189481;27846271;31398318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC075954.1, GFIL01045187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_001038229.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells., [UniProtKB, UniProtKB]; These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B857", "ec_number_list": [], "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity;GO:0030297 transmembrane receptor protein tyrosine kinase activator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0051781 positive regulation of cell division;GO:0045840 positive regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4INZ6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP02-1", "uniprot_id": [ { "id": "A0A0R4IP02_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP02", "type": "external" } ], "mass": 73917.0, "length": 658, "protein_name": "Kelch-like family member 13; Kelch-like protein 13 isoform X4", "gene_name": "klhl13", "organism": "Zebrafish", "refseq_name": "kelch-like protein 13 isoform X4", "refseq_ac": [ { "id": "XP_005165331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165331", "type": "external" } ], "gene_names_uniprotkb": "klhl13; wu:fc15b07; zgc:163008", "gene_names_refseq": "klhl13; wu:fc15b07; zgc:163008", "protein_names_uniprotkb": "Kelch-like family member 13; Kelch-like protein 13 isoform X4", "protein_names_refseq": "kelch-like protein 13 isoform X4", "tax_id": 7955, "disease": "", "pathway": " (dre:323951); (R-DRE-8951664); (R-DRE-983168)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "23594743;23843192;26469318", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BCJ0", "ec_number_list": [], "go_molecular_function": "GO:0097602 cullin family protein binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0051301 cell division;GO:0016567 protein ubiquitination;GO:0032465 regulation of cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IP02-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP03-1", "uniprot_id": [ { "id": "A0A0R4IP03_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP03", "type": "external" } ], "mass": 56930.0, "length": 499, "protein_name": "Cytochrome P450 2AA8; Cytochrome P450, family 2, subfamily AA, polypeptide 8", "gene_name": "cyp2aa8", "organism": "Zebrafish", "refseq_name": "cytochrome P450 2AA8", "refseq_ac": [ { "id": "NP_001006080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006080", "type": "external" } ], "gene_names_uniprotkb": "cyp2aa8; zgc:101673", "gene_names_refseq": "cyp2aa8; zgc:101673", "protein_names_uniprotkb": "Cytochrome P450 2AA8; Cytochrome P450, family 2, subfamily AA, polypeptide 8", "protein_names_refseq": "cytochrome P450 2AA8", "tax_id": 7955, "disease": "", "pathway": " (dre:450060); (R-DRE-211935); (R-DRE-211981); (R-DRE-211999); (R-DRE-9027307); (R-DRE-9749641)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "21087487;21116621;22297719;22931925;23594743;23726801;27189481;27444789;28411468;29259843;29725939", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01007948.1, BC083240.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001006080.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PWG4", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IP03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP11-1", "uniprot_id": [ { "id": "ORA4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP11", "type": "external" } ], "mass": 37804.0, "length": 344, "protein_name": "Olfactory receptor class A-like protein 4", "gene_name": "ora4", "organism": "Zebrafish", "refseq_name": "olfactory receptor class A-like protein 4", "refseq_ac": [ { "id": "NP_001410742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410742", "type": "external" } ], "gene_names_uniprotkb": "ora4", "gene_names_refseq": "ora4", "protein_names_uniprotkb": "Olfactory receptor class A-like protein 4", "protein_names_refseq": "olfactory receptor class A (V1r-like homolog); olfactory receptor class A-like protein 4", "tax_id": 7955, "disease": "", "pathway": " (dre:100004842)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17717047;22038944;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.21302788.1, SRR32588730.11163957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476815, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1 and AM778166.1. On Aug 16, 2023 this sequence version replaced XP_005168339.1., [RefSeq]; Probable olfactory receptor., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A8E0X0;F6P1D8", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IP11-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP12-1", "uniprot_id": [ { "id": "A0A0R4IP12_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP12", "type": "external" } ], "mass": 159796.0, "length": 1408, "protein_name": "PDS5 cohesin-associated factor B; Sister chromatid cohesion protein PDS5 homolog B", "gene_name": "pds5b", "organism": "Zebrafish", "refseq_name": "sister chromatid cohesion protein PDS5 homolog B", "refseq_ac": [ { "id": "XP_693953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693953", "type": "external" } ], "gene_names_uniprotkb": "pds5b", "gene_names_refseq": "pds5b", "protein_names_uniprotkb": "PDS5 cohesin-associated factor B; Sister chromatid cohesion protein PDS5 homolog B", "protein_names_refseq": "sister chromatid cohesion protein PDS5 homolog B", "tax_id": 7955, "disease": "", "pathway": " (dre:565592); (R-DRE-2467813); (R-DRE-2468052); (R-DRE-2470946); (R-DRE-2500257)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_693953.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVY5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0140670 cohesin unloader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0051301 cell division;GO:0007064 mitotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IP12-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP53-1", "uniprot_id": [ { "id": "A0A0R4IP53_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP53", "type": "external" } ], "mass": 115258.0, "length": 1001, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "taok1b", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase TAO1-B", "refseq_ac": [ { "id": "XP_009293944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009293944", "type": "external" } ], "gene_names_uniprotkb": "taok1b", "gene_names_refseq": "taok1b", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase TAO1-B", "tax_id": 7955, "disease": "", "pathway": " (dre:554108); (R-DRE-141430); (R-DRE-141444); (R-DRE-2467813); (R-DRE-2500257); (R-DRE-5663220)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AU74", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0046330 positive regulation of JNK cascade;GO:0051493 regulation of cytoskeleton organization;GO:0032874 positive regulation of stress-activated MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IP53-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP63-1", "uniprot_id": [ { "id": "A0A0R4IP63_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP63", "type": "external" } ], "mass": 53238.0, "length": 490, "protein_name": "G patch domain-containing protein 2; Si:ch73-21k16.4", "gene_name": "gpatch2", "organism": "Zebrafish", "refseq_name": "G patch domain-containing protein 2", "refseq_ac": [ { "id": "NP_001313622", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313622", "type": "external" } ], "gene_names_uniprotkb": "gpatch2; si:ch211-57i17.3; si:ch73-21k16.4", "gene_names_refseq": "gpatch2; si:ch211-57i17.3; si:ch73-21k16.4", "protein_names_uniprotkb": "G patch domain-containing protein 2; Si:ch73-21k16.4", "protein_names_refseq": "G patch domain-containing protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:555214)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588735.3134105.1, SRR32588715.1048139.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On May 24, 2016 this sequence version replaced XP_009293251.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P865", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IP63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP71-1", "uniprot_id": [ { "id": "A0A0R4IP71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP71", "type": "external" } ], "mass": 19202.0, "length": 170, "protein_name": "Telomerase RNA component interacting RNase", "gene_name": "trir", "organism": "Zebrafish", "refseq_name": "telomerase RNA component interacting RNase", "refseq_ac": [ { "id": "NP_001373564", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373564", "type": "external" } ], "gene_names_uniprotkb": "trir; gb:ct662408; si:ch73-152o7.1", "gene_names_refseq": "gb:ct662408; si:ch73-152o7.1; trir", "protein_names_uniprotkb": "Telomerase RNA component interacting RNase", "protein_names_refseq": "telomerase RNA component interacting RNase", "tax_id": 7955, "disease": "", "pathway": " (dre:560758)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;35175196", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01023309.1, CT721638.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1, EH472755.1 and EH499767.1. On Aug 27, 2020 this sequence version replaced XP_684751.1. Sequence Note: The RefSeq transcript was derived from the reference genome assembly. The genomic coordinates were determined from alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TCT6", "ec_number_list": [], "go_molecular_function": "GO:0008408 3'-5' exonuclease activity;GO:0008409 5'-3' exonuclease activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IP71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP88-1", "uniprot_id": [ { "id": "A0A0R4IP88_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP88", "type": "external" } ], "mass": 21635.0, "length": 214, "protein_name": "Si:dkey-225f23.5; Transmembrane protein 275", "gene_name": "tmem275a", "organism": "Zebrafish", "refseq_name": "transmembrane protein 275", "refseq_ac": [ { "id": "XP_005171257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171257", "type": "external" } ], "gene_names_uniprotkb": "tmem275a", "gene_names_refseq": "tmem275a", "protein_names_uniprotkb": "Si:dkey-225f23.5; Transmembrane protein 275", "protein_names_refseq": "transmembrane protein 275", "tax_id": 7955, "disease": "", "pathway": " (dre:101884107)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BIH1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IP88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP89-1", "uniprot_id": [ { "id": "A0A0R4IP89_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP89", "type": "external" } ], "mass": 25186.0, "length": 221, "protein_name": "Si:ch211-207l14.1", "gene_name": "si:ch211-207l14.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-207l14.1", "refseq_ac": [ { "id": "XP_690894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690894", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-207l14.1", "gene_names_refseq": "si:ch211-207l14.1", "protein_names_uniprotkb": "Si:ch211-207l14.1", "protein_names_refseq": "uncharacterized protein si:ch211-207l14.1", "tax_id": 7955, "disease": "", "pathway": " (dre:562414)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_690894.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q043", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IP89-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IP93-1", "uniprot_id": [ { "id": "A0A0R4IP93_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IP93", "type": "external" } ], "mass": 8070.0, "length": 70, "protein_name": "Si:dkey-92j12.6; Small integral membrane protein 18", "gene_name": "smim18", "organism": "Zebrafish", "refseq_name": "small integral membrane protein 18", "refseq_ac": [ { "id": "NP_001289983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289983", "type": "external" } ], "gene_names_uniprotkb": "smim18; si:dkey-92j12.6", "gene_names_refseq": "si:dkey-92j12.6; smim18", "protein_names_uniprotkb": "Si:dkey-92j12.6; Small integral membrane protein 18", "protein_names_refseq": "small integral membrane protein 18", "tax_id": 7955, "disease": "", "pathway": " (dre:101886416)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AL926886.1, EH471163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476768 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1 and EH438069.1. On Dec 16, 2014 this sequence version replaced XP_005170996.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P661", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IP93-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPB1-1", "uniprot_id": [ { "id": "A0A0R4IPB1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPB1", "type": "external" } ], "mass": 52358.0, "length": 451, "protein_name": "Tripartite motif-containing 35-21", "gene_name": "trim35-21", "organism": "Zebrafish", "refseq_name": "tripartite motif containing 35-21", "refseq_ac": [ { "id": "NP_001038429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038429", "type": "external" } ], "gene_names_uniprotkb": "trim35-21; si:ch211-175l6.8", "gene_names_refseq": "si:ch211-175l6.8; trim35-21", "protein_names_uniprotkb": "Tripartite motif-containing 35-21", "protein_names_refseq": "nuclear factor 7, brain-like; tripartite motif containing 35-21", "tax_id": 7955, "disease": "", "pathway": " (dre:561579)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21789205;23594743;28603526", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1216600.1, SRR32588722.44915640.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505378, SAMEA3505386 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000003.1. On Sep 1, 2006 this sequence version replaced XP_690085.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9Q5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IPB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPC1-1", "uniprot_id": [ { "id": "A0A0R4IPC1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPC1", "type": "external" } ], "mass": 8238.0, "length": 76, "protein_name": "Si:dkey-77g12.4; Uncharacterized protein LOC100537859 precursor", "gene_name": "spink2.11", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100537859 precursor", "refseq_ac": [ { "id": "NP_001373519", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373519", "type": "external" } ], "gene_names_uniprotkb": "spink2.11; si:dkey-77g12.4", "gene_names_refseq": "si:dkey-77g12.4; spink2.11", "protein_names_uniprotkb": "Si:dkey-77g12.4; Uncharacterized protein LOC100537859 precursor", "protein_names_refseq": "uncharacterized protein LOC100537859 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100537859)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CO356303.1, GFIL01020172.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476729, SAMEA4476751 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_003199921.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RJ19", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IPC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPF7-1", "uniprot_id": [ { "id": "A0A0R4IPF7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPF7", "type": "external" } ], "mass": 9536.0, "length": 90, "protein_name": "Si:dkey-6a5.3; Uncharacterized protein LOC100034415", "gene_name": "si:dkey-6a5.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100034415", "refseq_ac": [ { "id": "NP_001076521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076521", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-6a5.3", "gene_names_refseq": "si:dkey-6a5.3", "protein_names_uniprotkb": "Si:dkey-6a5.3; Uncharacterized protein LOC100034415", "protein_names_refseq": "uncharacterized protein LOC100034415", "tax_id": 7955, "disease": "", "pathway": " (dre:100034415)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12618376;23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA708832, SAMN18715721 [ECO:0000350] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000004.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NC94", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IPF7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPI9-1", "uniprot_id": [ { "id": "A0A0R4IPI9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPI9", "type": "external" } ], "mass": 60287.0, "length": 553, "protein_name": "G protein-coupled receptor 75; Probable G-protein coupled receptor 75", "gene_name": "gpr75", "organism": "Zebrafish", "refseq_name": "probable G-protein coupled receptor 75", "refseq_ac": [ { "id": "XP_009305768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305768", "type": "external" } ], "gene_names_uniprotkb": "gpr75", "gene_names_refseq": "gpr75", "protein_names_uniprotkb": "G protein-coupled receptor 75; Probable G-protein coupled receptor 75", "protein_names_refseq": "probable G-protein coupled receptor 75", "tax_id": 7955, "disease": "", "pathway": " (dre:100538001)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AZB7", "ec_number_list": [], "go_molecular_function": "GO:0016493 C-C chemokine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IPI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPJ5-1", "uniprot_id": [ { "id": "A0A0R4IPJ5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPJ5", "type": "external" } ], "mass": 11147.0, "length": 97, "protein_name": "Chemokine (C-C motif) ligand 34b, duplicate 1", "gene_name": "ccl34b.1", "organism": "Zebrafish", "refseq_name": "chemokine (C-C motif) ligand 34b, duplicate 1 precursor", "refseq_ac": [ { "id": "NP_001108526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108526", "type": "external" } ], "gene_names_uniprotkb": "ccl34b.1; si:dkey-25o1.6", "gene_names_refseq": "ccl34b.1; si:dkey-25o1.6", "protein_names_uniprotkb": "Chemokine (C-C motif) ligand 34b, duplicate 1", "protein_names_refseq": "CCL-chr24m; CCL34ba; Dr22_WGA1631_1_283786; chemokine (C-C motif) ligand 34b, duplicate 1 precursor; chemokine CCL-C24m", "tax_id": 7955, "disease": "", "pathway": " (dre:563952)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16365434;16697551;18482437;23145839;23594743;27189481;30067976;33208372;35111746;36122226;37196825", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH471624.1, EH445745.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jul 21, 2011 this sequence version replaced NP_001108526.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1TQT2", "ec_number_list": [], "go_molecular_function": "GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IPJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPL1-1", "uniprot_id": [ { "id": "A0A0R4IPL1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPL1", "type": "external" } ], "mass": 15027.0, "length": 140, "protein_name": "Profilin", "gene_name": "pfn2b", "organism": "Zebrafish", "refseq_name": "profilin-2 isoform X1", "refseq_ac": [ { "id": "XP_005174113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174113", "type": "external" } ], "gene_names_uniprotkb": "pfn2b; pfn2; wu:fb01g08; wu:fb54f09; wu:fd58f06", "gene_names_refseq": "pfn2b; pfn2; wu:fb01g08; wu:fb54f09; wu:fd58f06", "protein_names_uniprotkb": "Profilin", "protein_names_refseq": "profilin-2 isoform X1", "tax_id": 7955, "disease": "membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:394235); (R-DRE-4086400); (R-DRE-5663220)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "16109975;19240126;23594743;24271012;26469318;27235108;28252024;30948728;31142542;33945241;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLC7", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0032233 positive regulation of actin filament bundle assembly;GO:0030036 actin cytoskeleton organization;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "A0A0R4IPL1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPL6-1", "uniprot_id": [ { "id": "A0A0R4IPL6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPL6", "type": "external" } ], "mass": 21188.0, "length": 188, "protein_name": "Calcyphosine-like a", "gene_name": "capsla", "organism": "Zebrafish", "refseq_name": "calcyphosine-like a isoform X1", "refseq_ac": [ { "id": "XP_009297198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297198", "type": "external" } ], "gene_names_uniprotkb": "capsla; capsl; wu:fj05b10; zgc:112473", "gene_names_refseq": "capsla; capsl; wu:fj05b10; zgc:112473", "protein_names_uniprotkb": "Calcyphosine-like a", "protein_names_refseq": "calcyphosine-like a isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:550371)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16109975;23594743;25417113", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B0K1", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IPL6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPM5-1", "uniprot_id": [ { "id": "A0A0R4IPM5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPM5", "type": "external" } ], "mass": 29834.0, "length": 278, "protein_name": "Sp6 transcription factor; Transcription factor Sp6 isoform X1", "gene_name": "sp6", "organism": "Zebrafish", "refseq_name": "transcription factor Sp6 isoform X1", "refseq_ac": [ { "id": "XP_009294533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294533", "type": "external" } ], "gene_names_uniprotkb": "sp6; zgc:77358", "gene_names_refseq": "sp6; zgc:77358", "protein_names_uniprotkb": "Sp6 transcription factor; Transcription factor Sp6 isoform X1", "protein_names_refseq": "transcription factor Sp6 isoform X1", "tax_id": 7955, "disease": "amelogenesis imperfecta type 1K (Disease Ontology:DOID:0060945); amelogenesis imperfecta (Disease Ontology:DOID:2187)", "pathway": " (dre:402928)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12477932;21873635;23594743;35134499", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AM93", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IPM5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPP3-1", "uniprot_id": [ { "id": "A0A0R4IPP3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPP3", "type": "external" } ], "mass": 53134.0, "length": 470, "protein_name": "Si:ch73-109d9.3; Zinc finger protein 853", "gene_name": "si:ch73-109d9.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-109d9.3", "refseq_ac": [ { "id": "XP_005160142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160142", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-109d9.3", "gene_names_refseq": "si:ch73-109d9.3", "protein_names_uniprotkb": "Si:ch73-109d9.3; Zinc finger protein 853", "protein_names_refseq": "uncharacterized protein si:ch73-109d9.3", "tax_id": 7955, "disease": "", "pathway": " (dre:101883524)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6Y7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IPP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPP5-1", "uniprot_id": [ { "id": "A0A0R4IPP5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPP5", "type": "external" } ], "mass": 27715.0, "length": 252, "protein_name": "Uncharacterized protein LOC562658 precursor; Zgc:152863", "gene_name": "wu:fi06c08", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC562658 precursor", "refseq_ac": [ { "id": "NP_001073469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073469", "type": "external" } ], "gene_names_uniprotkb": "wu:fi06c08; zgc:152863", "gene_names_refseq": "wu:fi06c08; zgc:152863", "protein_names_uniprotkb": "Uncharacterized protein LOC562658 precursor; Zgc:152863", "protein_names_refseq": "uncharacterized protein LOC562658 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:562658)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC125825.1, GDQQ01017953.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001073469.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3APT4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IPP5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPR8-1", "uniprot_id": [ { "id": "A0A0R4IPR8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPR8", "type": "external" } ], "mass": 83501.0, "length": 761, "protein_name": "ARF GTPase-activating protein GIT1 isoform X1; G protein-coupled receptor kinase-interacting ArfGAP 1", "gene_name": "git1", "organism": "Zebrafish", "refseq_name": "ARF GTPase-activating protein GIT1 isoform X1", "refseq_ac": [ { "id": "XP_697386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697386", "type": "external" } ], "gene_names_uniprotkb": "git1", "gene_names_refseq": "git1", "protein_names_uniprotkb": "ARF GTPase-activating protein GIT1 isoform X1; G protein-coupled receptor kinase-interacting ArfGAP 1", "protein_names_refseq": "ARF GTPase-activating protein GIT1 isoform X1", "tax_id": 7955, "disease": "attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (dre:568935); (R-DRE-3928664); (R-DRE-9013148); (R-DRE-9013149); (R-DRE-9013404); (R-DRE-9013406); (R-DRE-9013420); (R-DRE-9013423); (R-DRE-9013424)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_697386.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVA0", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0045202 synapse;GO:0098794 postsynapse;GO:0043005 neuron projection;GO:0098793 presynapse", "go_biological_process": "GO:0001525 angiogenesis;GO:0007420 brain development;GO:0001568 blood vessel development;GO:0036465 synaptic vesicle recycling;GO:0032012 regulation of ARF protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IPR8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPT5-1", "uniprot_id": [ { "id": "A0A0R4IPT5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPT5", "type": "external" } ], "mass": 68133.0, "length": 618, "protein_name": "Lipolysis-stimulated lipoprotein receptor", "gene_name": "lsr", "organism": "Zebrafish", "refseq_name": "lipolysis-stimulated lipoprotein receptor isoform X1", "refseq_ac": [ { "id": "XP_005157688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157688", "type": "external" } ], "gene_names_uniprotkb": "lsr; Lisch7; lsrl; zgc:114089", "gene_names_refseq": "Lisch7; lsrl; lsr; zgc:114089", "protein_names_uniprotkb": "Lipolysis-stimulated lipoprotein receptor", "protein_names_refseq": "lipolysis-stimulated lipoprotein receptor isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:553218)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "18654634;21255762;23594743;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3Y8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005923 bicellular tight junction;GO:0012505 endomembrane system;GO:0005886 plasma membrane;GO:0061689 tricellular tight junction", "go_biological_process": "GO:0031016 pancreas development;GO:0007492 endoderm development;GO:0060856 establishment of blood-brain barrier;GO:1904274 tricellular tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IPT5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPV5-1", "uniprot_id": [ { "id": "A0A0R4IPV5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPV5", "type": "external" } ], "mass": 56634.0, "length": 509, "protein_name": "Protein disulfide-isomerase", "gene_name": "p4hb", "organism": "Zebrafish", "refseq_name": "protein disulfide-isomerase precursor", "refseq_ac": [ { "id": "NP_998529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998529", "type": "external" } ], "gene_names_uniprotkb": "p4hb; psmb3; zgc:92596", "gene_names_refseq": "p4hb; psmb3; zgc:92596", "protein_names_uniprotkb": "Protein disulfide-isomerase; 5.3.4.1", "protein_names_refseq": "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; protein disulfide-isomerase precursor", "tax_id": 7955, "disease": "Cole-Carpenter syndrome (Disease Ontology:DOID:0060438)", "pathway": " (dre:406673); (R-DRE-1650814); (R-DRE-264876); (R-DRE-3299685); (R-DRE-381426); (R-DRE-5358346); (R-DRE-8957275); (R-DRE-8964041); (R-DRE-9020591)", "pathway_count": 9, "publication_count": 9, "publication_id_list": "16109975;23427857;23594743;23798569;26657776;30359749;31680844;32467236;36283702", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB848925.1, EB796102.1, BI890770.1, CV487860.1 and BX005286.6. On Jul 3, 2008 this sequence version replaced NP_998529.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4ISX6;A0A8M1PGX7", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "3.1.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.98", "type": "external" }, { "id": "3.4.21.112", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.112", "type": "external" }, { "id": "3.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.51", "type": "external" }, { "id": "3.4.21.69", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.69", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0005886 plasma membrane", "go_biological_process": "GO:0006457 protein folding;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IPV5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPW1-1", "uniprot_id": [ { "id": "A0A0R4IPW1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPW1", "type": "external" } ], "mass": 28962.0, "length": 258, "protein_name": "SPRY domain-containing protein isoform 1; Si:ch211-214b16.2", "gene_name": "si:ch211-214b16.2", "organism": "Zebrafish", "refseq_name": "SPRY domain-containing protein isoform 1", "refseq_ac": [ { "id": "NP_001373508", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373508", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-214b16.2", "gene_names_refseq": "si:ch211-214b16.2", "protein_names_uniprotkb": "SPRY domain-containing protein isoform 1; Si:ch211-214b16.2", "protein_names_refseq": "SPRY domain-containing protein isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:799802)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CT614240.2, CO920769.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Aug 29, 2020 this sequence version replaced XP_017210345.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YXS8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IPW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPW5-1", "uniprot_id": [ { "id": "A0A0R4IPW5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPW5", "type": "external" } ], "mass": 63524.0, "length": 576, "protein_name": "Carboxylic ester hydrolase", "gene_name": "si:ch73-89b15.3", "organism": "Zebrafish", "refseq_name": "cAMP-regulated D2 protein isoform X1", "refseq_ac": [ { "id": "XP_002661384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661384", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-89b15.3; LOC100334697", "gene_names_refseq": "si:ch73-89b15.3", "protein_names_uniprotkb": "Carboxylic ester hydrolase; 3.1.1.-", "protein_names_refseq": "cAMP-regulated D2 protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334697)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002661384.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RLQ9", "ec_number_list": [], "go_molecular_function": "GO:0004104 cholinesterase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IPW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IPY6-1", "uniprot_id": [ { "id": "A0A0R4IPY6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IPY6", "type": "external" } ], "mass": 109779.0, "length": 961, "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "ocrl", "organism": "Zebrafish", "refseq_name": "inositol polyphosphate 5-phosphatase OCRL isoform X1", "refseq_ac": [ { "id": "XP_009289414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289414", "type": "external" } ], "gene_names_uniprotkb": "ocrl; wu:fi09g03; zgc:152864", "gene_names_refseq": "ocrl; wu:fi09g03; zgc:152864", "protein_names_uniprotkb": "Inositol polyphosphate 5-phosphatase OCRL; 3.1.3.36; 3.1.3.56; 3.1.3.86; Inositol polyphosphate 5-phosphatase OCRL-1; Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase", "protein_names_refseq": "inositol polyphosphate 5-phosphatase OCRL isoform X1", "tax_id": 7955, "disease": "Dent disease 2 (Disease Ontology:DOID:0081454); oculocerebrorenal syndrome (Disease Ontology:DOID:1056)", "pathway": " (dre:777716); (R-DRE-1660499); (R-DRE-1660514); (R-DRE-1855183); (R-DRE-1855204); (R-DRE-9013409); (R-DRE-9013423)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "22210625;22228094;22543976;22680056;23594743;23739214;31676724;31811534;34673953;35716957;35979861", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2. Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate. Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes. Involved in primary cilia assembly. Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AS36", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.134", "type": "external" }, { "id": "2.7.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.159", "type": "external" } ], "go_molecular_function": "GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445 inositol-polyphosphate 5-phosphatase activity;GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005905 clathrin-coated pit;GO:0016020 membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction;GO:0030100 regulation of endocytosis;GO:0001919 regulation of receptor recycling;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IPY6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ09-1", "uniprot_id": [ { "id": "A0A0R4IQ09_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ09", "type": "external" } ], "mass": 18943.0, "length": 164, "protein_name": "Si:ch211-260e23.9; Uncharacterized protein LOC555795", "gene_name": "si:ch211-260e23.9", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC555795", "refseq_ac": [ { "id": "NP_001373653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373653", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-260e23.9", "gene_names_refseq": "si:ch211-260e23.9", "protein_names_uniprotkb": "Si:ch211-260e23.9; Uncharacterized protein LOC555795", "protein_names_refseq": "tumor protein p53-inducible nuclear protein 2-like; uncharacterized protein LOC555795", "tax_id": 7955, "disease": "", "pathway": " (dre:555795)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH582322.1, SRR32588723.1234800.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Sep 2, 2020 this sequence version replaced XP_021333622.1, XP_703224.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PQ22", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0031410 cytoplasmic vesicle;GO:0016604 nuclear body;GO:0005776 autophagosome", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IQ09-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ14-1", "uniprot_id": [ { "id": "A0A0R4IQ14_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ14", "type": "external" } ], "mass": 74210.0, "length": 661, "protein_name": "RING finger protein 214; Si:dkey-111e8.1", "gene_name": "rnf214", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rnf214", "gene_names_refseq": "", "protein_names_uniprotkb": "RING finger protein 214; Si:dkey-111e8.1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:323719); (R-DRE-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QER6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQ14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ22-1", "uniprot_id": [ { "id": "A0A0R4IQ22_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ22", "type": "external" } ], "mass": 27964.0, "length": 245, "protein_name": "Microfibril-associated glycoprotein 4-like precursor; Si:ch1073-110a20.7", "gene_name": "mfap4.5", "organism": "Zebrafish", "refseq_name": "microfibril-associated glycoprotein 4-like precursor", "refseq_ac": [ { "id": "NP_001315007", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315007", "type": "external" } ], "gene_names_uniprotkb": "mfap4.5; LOC100007488", "gene_names_refseq": "mfap4.5; si:ch1073-110a20.7", "protein_names_uniprotkb": "Microfibril-associated glycoprotein 4-like precursor; Si:ch1073-110a20.7", "protein_names_refseq": "mfap4-like; microfibril-associated glycoprotein 4-like precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100007488)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15837522;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH507201.1, SRR32588734.2588579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476734, SAMEA4476750 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1, EH504788.1 and EH530966.1. On Jun 3, 2016 this sequence version replaced XP_005171112.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3I3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007596 blood coagulation;GO:0048251 elastic fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IQ22-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ46-1", "uniprot_id": [ { "id": "A0A0R4IQ46_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ46", "type": "external" } ], "mass": 57145.0, "length": 501, "protein_name": "Cytochrome P450 2AA12; Cytochrome P450, family 2, subfamily AA, polypeptide 12", "gene_name": "cyp2aa12", "organism": "Zebrafish", "refseq_name": "cytochrome P450 2AA12", "refseq_ac": [ { "id": "NP_001103171", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103171", "type": "external" } ], "gene_names_uniprotkb": "cyp2aa12; zgc:171945", "gene_names_refseq": "cyp2aa12; zgc:171945", "protein_names_uniprotkb": "Cytochrome P450 2AA12; Cytochrome P450, family 2, subfamily AA, polypeptide 12", "protein_names_refseq": "cytochrome P450 2AA12", "tax_id": 7955, "disease": "", "pathway": " (dre:555510); (R-DRE-211935); (R-DRE-211981); (R-DRE-211999); (R-DRE-9027307); (R-DRE-9749641)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "21087487;21116621;23594743;23711412;23726801;25424564;28193729;28411468;29376370;29725939;33396047", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC152006.1, SRR32588731.2173611.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505393, SAMEA4476771 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jul 8, 2025 this sequence version replaced NP_001103171.2. Sequence Note:. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IQV4;A0A8M1NG29", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IQ46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ55-1", "uniprot_id": [ { "id": "A0A0R4IQ55_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ55", "type": "external" } ], "mass": 39203.0, "length": 361, "protein_name": "Porphobilinogen deaminase", "gene_name": "hmbsa", "organism": "Zebrafish", "refseq_name": "hydroxymethylbilane synthase a isoform X1", "refseq_ac": [ { "id": "XP_005171873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171873", "type": "external" } ], "gene_names_uniprotkb": "hmbsa; hmbs; zgc:64128", "gene_names_refseq": "hmbsa; hmbs; zgc:64128", "protein_names_uniprotkb": "Porphobilinogen deaminase; 2.5.1.61; Hydroxymethylbilane synthase", "protein_names_refseq": "hydroxymethylbilane synthase a isoform X1", "tax_id": 7955, "disease": "prostate carcinoma (Disease Ontology:DOID:10286); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); acute intermittent porphyria (Disease Ontology:DOID:3890); seminoma (Disease Ontology:DOID:4440)", "pathway": " (dre:394129); (R-DRE-189451)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "16889661;17671813;20828405;23594743;26469318;27189481;29248853;30309860;32051014;34185526;36420817", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJ45", "ec_number_list": [ { "id": "2.5.1.61", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.61", "type": "external" } ], "go_molecular_function": "GO:0004418 hydroxymethylbilane synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IQ55-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ63-1", "uniprot_id": [ { "id": "A0A0R4IQ63_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ63", "type": "external" } ], "mass": 57443.0, "length": 502, "protein_name": "Cytochrome P450 2K16; Cytochrome P450, family 2, subfamily K, polypeptide16", "gene_name": "cyp2k16", "organism": "Zebrafish", "refseq_name": "cytochrome P450 2K16", "refseq_ac": [ { "id": "NP_001005963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005963", "type": "external" } ], "gene_names_uniprotkb": "cyp2k16; si:ch211-155i15.2; zgc:101876", "gene_names_refseq": "cyp2k16; si:ch211-155i15.2; zgc:101876", "protein_names_uniprotkb": "Cytochrome P450 2K16; Cytochrome P450, family 2, subfamily K, polypeptide16", "protein_names_refseq": "cytochrome P450 2K16", "tax_id": 7955, "disease": "", "pathway": " (dre:449790)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21087487;21116621;23594743;28411468", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC083304.1, GDQQ01006463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Aug 27, 2015 this sequence version replaced NP_001005963.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N2L4", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process;GO:0046222 aflatoxin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IQ63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQ88-1", "uniprot_id": [ { "id": "A0A0R4IQ88_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQ88", "type": "external" } ], "mass": 67051.0, "length": 618, "protein_name": "D-glutamate cyclase, mitochondrial", "gene_name": "dglucy", "organism": "Zebrafish", "refseq_name": "D-glutamate cyclase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_001923890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923890", "type": "external" } ], "gene_names_uniprotkb": "dglucy", "gene_names_refseq": "dglucy", "protein_names_uniprotkb": "D-glutamate cyclase, mitochondrial; 4.2.1.48", "protein_names_refseq": "D-glutamate cyclase, mitochondrial isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:560387)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; D-glutamate cyclase that converts D-glutamate to 5-oxo-D-proline., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QRC9", "ec_number_list": [ { "id": "4.2.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.48", "type": "external" } ], "go_molecular_function": "GO:0047820 D-glutamate cyclase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006536 glutamate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQ88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQB8-1", "uniprot_id": [ { "id": "A0A0R4IQB8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQB8", "type": "external" } ], "mass": 95480.0, "length": 838, "protein_name": "pre-rRNA processing protein FTSJ3", "gene_name": "ftsj3", "organism": "Zebrafish", "refseq_name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "refseq_ac": [ { "id": "NP_001292397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292397", "type": "external" } ], "gene_names_uniprotkb": "ftsj3; FTSJ3; cb410; ftsj; sb:cb410; wu:fa08a09", "gene_names_refseq": "cb410; ftsj3; ftsj; sb:cb410; wu:fa08a09", "protein_names_uniprotkb": "pre-rRNA processing protein FTSJ3; 2'-O-ribose RNA methyltransferase SPB1 homolog; 2.1.1.-; Protein ftsJ homolog 3; Putative rRNA methyltransferase 3", "protein_names_refseq": "FtsJ RNA methyltransferase homolog 3; FtsJ homolog 3; pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "tax_id": 7955, "disease": "", "pathway": " (dre:321247)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;24198278;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588735.621293.1, SRR32588720.1751268.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1, CT583766.2, EB793829.1 and CT635598.2. On Mar 18, 2015 this sequence version replaced XP_002666179.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1T0", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0016435 rRNA (guanine) methyltransferase activity;GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0031167 rRNA methylation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IQB8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQE1-1", "uniprot_id": [ { "id": "A0A0R4IQE1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQE1", "type": "external" } ], "mass": 87783.0, "length": 775, "protein_name": "Thioredoxin domain-containing 11; Thioredoxin domain-containing protein 11", "gene_name": "txndc11", "organism": "Zebrafish", "refseq_name": "thioredoxin domain-containing protein 11", "refseq_ac": [ { "id": "NP_001313634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313634", "type": "external" } ], "gene_names_uniprotkb": "txndc11; im:7137600", "gene_names_refseq": "im:7137600; txndc11", "protein_names_uniprotkb": "Thioredoxin domain-containing 11; Thioredoxin domain-containing protein 11", "protein_names_refseq": "thioredoxin domain-containing protein 11", "tax_id": 7955, "disease": "", "pathway": " (dre:100330433)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01010223.1, SRR26395039.548779.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On May 24, 2016 this sequence version replaced XP_002660719.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P970", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IQE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQG7-1", "uniprot_id": [ { "id": "A0A0R4IQG7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQG7", "type": "external" } ], "mass": 161845.0, "length": 1431, "protein_name": "Nitric oxide synthase", "gene_name": "nos1", "organism": "Zebrafish", "refseq_name": "nitric oxide synthase 1 isoform X1", "refseq_ac": [ { "id": "XP_005165110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165110", "type": "external" } ], "gene_names_uniprotkb": "nos1; nNOS; nnos; nos", "gene_names_refseq": "nNOS; nos1; nos", "protein_names_uniprotkb": "Nitric oxide synthase; 1.14.13.39", "protein_names_refseq": "nitric oxide synthase 1 isoform X1", "tax_id": 7955, "disease": "lissencephaly (Disease Ontology:DOID:0050453); cardiomyopathy (Disease Ontology:DOID:0050700); Parkinsonism (Disease Ontology:DOID:0080855); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); Alzheimer's disease (Disease Ontology:DOID:10652); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); nephrotic syndrome (Disease Ontology:DOID:1184); urethral obstruction (Disease Ontology:DOID:12577); hypertrophic pyloric stenosis (Disease Ontology:DOID:12638); alcoholic cardiomyopathy (Disease Ontology:DOID:12935); retinopathy of prematurity (Disease Ontology:DOID:13025); hepatic encephalopathy (Disease Ontology:DOID:13413); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); cystic fibrosis (Disease Ontology:DOID:1485); renovascular hypertension (Disease Ontology:DOID:1591); depressive disorder (Disease Ontology:DOID:1596); epilepsy (Disease Ontology:DOID:1826); impotence (Disease Ontology:DOID:1875); transient cerebral ischemia (Disease Ontology:DOID:224); motor neuron disease (Disease Ontology:DOID:231); brain ischemia (Disease Ontology:DOID:2316); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); end stage renal disease (Disease Ontology:DOID:783); diabetic retinopathy (Disease Ontology:DOID:8947); achalasia (Disease Ontology:DOID:9164); type 2 diabetes mellitus (Disease Ontology:DOID:9352); allergic asthma (Disease Ontology:DOID:9415); obesity (Disease Ontology:DOID:9970)", "pathway": " (R-DRE-1222556); (R-DRE-392154)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "12915313;14766951;16274840;16396911;18655843;23594743;35531980;35594629;35627303;35940686;37426341", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Produces nitric oxide (NO) which is a messenger molecule with diverse functions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 36, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BCC4;F1QVR0", "ec_number_list": [ { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" } ], "go_molecular_function": "GO:0004517 nitric-oxide synthase activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0043197 dendritic spine", "go_biological_process": "GO:0001889 liver development;GO:0032496 response to lipopolysaccharide;GO:0045776 negative regulation of blood pressure;GO:0060218 hematopoietic stem cell differentiation;GO:0007210 serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IQG7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQI6-1", "uniprot_id": [ { "id": "A0A0R4IQI6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQI6", "type": "external" } ], "mass": 72453.0, "length": 654, "protein_name": "Si:ch211-11n16.2; Zinc finger FYVE domain-containing protein 1 isoform X1", "gene_name": "si:ch211-11n16.2", "organism": "Zebrafish", "refseq_name": "zinc finger FYVE domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_691596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691596", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-11n16.2", "gene_names_refseq": "si:ch211-11n16.2", "protein_names_uniprotkb": "Si:ch211-11n16.2; Zinc finger FYVE domain-containing protein 1 isoform X1", "protein_names_refseq": "zinc finger FYVE domain-containing protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_691596.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UT50", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0005811 lipid droplet", "go_biological_process": "GO:0140042 lipid droplet formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQI6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQI7-1", "uniprot_id": [ { "id": "A0A0R4IQI7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQI7", "type": "external" } ], "mass": 123906.0, "length": 1121, "protein_name": "AP-4 complex subunit epsilon", "gene_name": "ap4e1", "organism": "Zebrafish", "refseq_name": "AP-4 complex subunit epsilon-1", "refseq_ac": [ { "id": "XP_699042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699042", "type": "external" } ], "gene_names_uniprotkb": "ap4e1", "gene_names_refseq": "ap4e1", "protein_names_uniprotkb": "AP-4 complex subunit epsilon", "protein_names_refseq": "AP-4 complex subunit epsilon-1", "tax_id": 7955, "disease": "stuttering (Disease Ontology:DOID:0060243); hereditary spastic paraplegia 51 (Disease Ontology:DOID:0110803)", "pathway": " (dre:570467); (R-DRE-432720)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_699042.1. COMPLETENESS: full length., [RefSeq]; Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFG6", "ec_number_list": [], "go_molecular_function": "GO:0140312 cargo adaptor activity", "go_cellular_component": "GO:0012505 endomembrane system;GO:0030124 AP-4 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQI7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQJ3-1", "uniprot_id": [ { "id": "A0A0R4IQJ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQJ3", "type": "external" } ], "mass": 444001.0, "length": 4003, "protein_name": "Extracellular matrix organizing protein FRAS1 isoform X1; Fraser extracellular matrix complex subunit 1", "gene_name": "fras1", "organism": "Zebrafish", "refseq_name": "extracellular matrix organizing protein FRAS1 isoform X1", "refseq_ac": [ { "id": "XP_005165392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165392", "type": "external" } ], "gene_names_uniprotkb": "fras1; id:ibd5080; pif; si:ch211-191a6.5; wu:fc10b09", "gene_names_refseq": "fras1; id:ibd5080; pif; si:ch211-191a6.5; wu:fc10b09", "protein_names_uniprotkb": "Extracellular matrix organizing protein FRAS1 isoform X1; Fraser extracellular matrix complex subunit 1", "protein_names_refseq": "extracellular matrix organizing protein FRAS1 isoform X1", "tax_id": 7955, "disease": "Fraser syndrome (Disease Ontology:DOID:0090001); Fraser syndrome 1 (Disease Ontology:DOID:0111405); clubfoot (Disease Ontology:DOID:11836)", "pathway": " (dre:563428)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11731487;18816440;20419147;21552255;23594743;30327840;31527654;32112658;33543035;35679135;9007245", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BCL6", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007154 cell communication;GO:0007492 endoderm development;GO:0010669 epithelial structure maintenance;GO:0009653 anatomical structure morphogenesis;GO:0048703 embryonic viscerocranium morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IQJ3-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQL7-1", "uniprot_id": [ { "id": "A0A0R4IQL7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQL7", "type": "external" } ], "mass": 49960.0, "length": 450, "protein_name": "Paired box protein Pax-6", "gene_name": "pax6b", "organism": "Zebrafish", "refseq_name": "paired box protein Pax-6b isoform X1", "refseq_ac": [ { "id": "XP_005168876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168876", "type": "external" } ], "gene_names_uniprotkb": "pax6b; Pax6.2; cb566; fc09c10; id:ibd5095; pax6.2; wu:fc09c10; wu:fc33g08", "gene_names_refseq": "Pax6.2; cb566; fc09c10; id:ibd5095; pax6b; wu:fc09c10; wu:fc33g08", "protein_names_uniprotkb": "Paired box protein Pax-6", "protein_names_refseq": "paired box protein Pax-6b isoform X1", "tax_id": 7955, "disease": "Peters anomaly (Disease Ontology:DOID:0060673); foveal hypoplasia 1 (Disease Ontology:DOID:0070530); aniridia 1 (Disease Ontology:DOID:0070532); anterior segment dysgenesis 5 (Disease Ontology:DOID:0080610); cataract 27 (Disease Ontology:DOID:0110233); autosomal dominant keratitis (Disease Ontology:DOID:0111383); bilateral optic nerve hypoplasia (Disease Ontology:DOID:0111531); glucose intolerance (Disease Ontology:DOID:10603); microphthalmia (Disease Ontology:DOID:10629); juvenile glaucoma (Disease Ontology:DOID:1068); coloboma of optic nerve (Disease Ontology:DOID:11975); aniridia (Disease Ontology:DOID:12271); paranoid schizophrenia (Disease Ontology:DOID:1229); autistic disorder (Disease Ontology:DOID:12849); Smith-Lemli-Opitz syndrome (Disease Ontology:DOID:14692); transient cerebral ischemia (Disease Ontology:DOID:224); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); cataract (Disease Ontology:DOID:83); type 2 diabetes mellitus (Disease Ontology:DOID:9352); congenital nystagmus (Disease Ontology:DOID:9649)", "pathway": " (dre:60639)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11731487;1352238;15081370;15496438;15533792;23594743;36334626;36361808;36362312;36594417;36627765;9831649", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z765", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030900 forebrain development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007420 brain development;GO:0060041 retina development in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0R4IQL7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQM9-1", "uniprot_id": [ { "id": "A0A0R4IQM9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQM9", "type": "external" } ], "mass": 68715.0, "length": 603, "protein_name": "Syntaxin-binding protein 1", "gene_name": "stxbp1a", "organism": "Zebrafish", "refseq_name": "syntaxin-binding protein 1a isoform X1", "refseq_ac": [ { "id": "XP_005161170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161170", "type": "external" } ], "gene_names_uniprotkb": "stxbp1a; fj43h10; stxbp1; wu:fj36d12; wu:fj43h10; zgc:114171", "gene_names_refseq": "fj43h10; stxbp1a; stxbp1; wu:fj36d12; wu:fj43h10; zgc:114171", "protein_names_uniprotkb": "Syntaxin-binding protein 1; Protein unc-18 homolog 1; Protein unc-18 homolog A", "protein_names_refseq": "syntaxin-binding protein 1a isoform X1", "tax_id": 7955, "disease": "West syndrome (Disease Ontology:DOID:0050562); developmental and epileptic encephalopathy 4 (Disease Ontology:DOID:0080436)", "pathway": " (dre:574003)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "20102740;23499359;23594743;25142379;26469318;26818140;27189481;28252024;28679150;28711009;33316259", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B819", "ec_number_list": [], "go_molecular_function": "GO:0017075 syntaxin-1 binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030141 secretory granule;GO:0098793 presynapse;GO:0016020 membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0099525 presynaptic dense core vesicle exocytosis;GO:1903305 regulation of regulated secretory pathway;GO:0006904 vesicle docking involved in exocytosis;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IQM9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQQ3-1", "uniprot_id": [ { "id": "A0A0R4IQQ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQQ3", "type": "external" } ], "mass": 32221.0, "length": 278, "protein_name": "Centriole, cilia and spindle-associated protein", "gene_name": "ccsapa", "organism": "Zebrafish", "refseq_name": "centriole, cilia and spindle-associated protein", "refseq_ac": [ { "id": "XP_005160215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160215", "type": "external" } ], "gene_names_uniprotkb": "ccsapa", "gene_names_refseq": "ccsapa", "protein_names_uniprotkb": "Centriole, cilia and spindle-associated protein", "protein_names_refseq": "centriole, cilia and spindle-associated protein", "tax_id": 7955, "disease": "", "pathway": " (dre:101883094)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6X5", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005819 spindle;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone", "go_biological_process": "GO:1901673 regulation of mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQW1-1", "uniprot_id": [ { "id": "A0A0R4IQW1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQW1", "type": "external" } ], "mass": 85163.0, "length": 754, "protein_name": "Si:ch211-276i12.4", "gene_name": "si:ch211-276i12.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-276i12.4 isoform X2", "refseq_ac": [ { "id": "XP_017214552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214552", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-276i12.4", "gene_names_refseq": "si:ch211-276i12.4", "protein_names_uniprotkb": "Si:ch211-276i12.4", "protein_names_refseq": "uncharacterized protein si:ch211-276i12.4 isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:793599)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z472", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQW8-1", "uniprot_id": [ { "id": "A0A0R4IQW8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQW8", "type": "external" } ], "mass": 36948.0, "length": 350, "protein_name": "Single-stranded DNA-binding protein 2", "gene_name": "ssbp2b", "organism": "Zebrafish", "refseq_name": "single-stranded DNA-binding protein 2 isoform X1", "refseq_ac": [ { "id": "XP_009303959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303959", "type": "external" } ], "gene_names_uniprotkb": "ssbp2b", "gene_names_refseq": "ssbp2b", "protein_names_uniprotkb": "Single-stranded DNA-binding protein 2", "protein_names_refseq": "single-stranded DNA-binding protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:798086)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AXA4", "ec_number_list": [], "go_molecular_function": "GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQY2-1", "uniprot_id": [ { "id": "A0A0R4IQY2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQY2", "type": "external" } ], "mass": 51408.0, "length": 455, "protein_name": "Kynureninase", "gene_name": "kynu", "organism": "Zebrafish", "refseq_name": "kynureninase", "refseq_ac": [ { "id": "XP_009300357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300357", "type": "external" } ], "gene_names_uniprotkb": "kynu; KYNU", "gene_names_refseq": "", "protein_names_uniprotkb": "Kynureninase; 3.7.1.3; L-kynurenine hydrolase", "protein_names_refseq": "", "tax_id": 7955, "disease": "hydroxykynureninuria (Disease Ontology:DOID:0112257)", "pathway": " (dre:100334830); (R-DRE-71240)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BA40", "ec_number_list": [ { "id": "3.7.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.7.1.3", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0030429 kynureninase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0097053 L-kynurenine catabolic process;GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0019805 quinolinate biosynthetic process;GO:0043420 anthranilate metabolic process;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IQY2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IQZ2-1", "uniprot_id": [ { "id": "ZDH13_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IQZ2", "type": "external" } ], "mass": 71440.0, "length": 645, "protein_name": "Putative palmitoyltransferase ZDHHC13", "gene_name": "zdhhc13", "organism": "Zebrafish", "refseq_name": "putative palmitoyltransferase ZDHHC13", "refseq_ac": [ { "id": "NP_001008650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008650", "type": "external" } ], "gene_names_uniprotkb": "zdhhc13", "gene_names_refseq": "DHHC-13; fi22e09; wu:fb06e01; wu:fc39g10; wu:fi22e09; zdhhc13; zgc:101690", "protein_names_uniprotkb": "Putative palmitoyltransferase ZDHHC13; DHHC domain-containing protein 13; DHHC-13; Zinc finger DHHC domain-containing protein 13", "protein_names_refseq": "DHHC domain-containing protein 13; palmitoyltransferase ZDHHC13; putative palmitoyltransferase ZDHHC13; zinc finger DHHC domain-containing protein 13; zinc finger DHHC-type containing 13; zinc finger DHHC-type palmitoyltransferase 13", "tax_id": 7955, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (dre:494107)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26056731;27235108", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01007406.1, GDQH01002717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Dec 3, 2011 this sequence version replaced NP_001008650.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Putative palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5PRB8", "ec_number_list": [], "go_molecular_function": "GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0030509 BMP signaling pathway;GO:0030510 regulation of BMP signaling pathway;GO:0042665 regulation of ectodermal cell fate specification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IQZ2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IR18-1", "uniprot_id": [ { "id": "A0A0R4IR18_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IR18", "type": "external" } ], "mass": 64132.0, "length": 564, "protein_name": "Activating signal cointegrator 1", "gene_name": "trip4", "organism": "Zebrafish", "refseq_name": "activating signal cointegrator 1", "refseq_ac": [ { "id": "NP_001071043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071043", "type": "external" } ], "gene_names_uniprotkb": "trip4; dZ221I3.1; im:7143009; si:busm1-221i3.1; si:dkey-173l11.4; zgc:153348", "gene_names_refseq": "dZ221I3.1; im:7143009; si:busm1-221i3.1; si:dkey-173l11.4; trip4; zgc:153348", "protein_names_uniprotkb": "Activating signal cointegrator 1; Thyroid receptor-interacting protein 4", "protein_names_refseq": "activating signal cointegrator 1", "tax_id": 7955, "disease": "", "pathway": " (dre:568585)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26924529;33771997", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124323.1, GDQH01022788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505388, SAMEA3505393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 19, 2009 this sequence version replaced NP_001071043.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. May play a role in the development of neuromuscular junction. May play a role in late myogenic differentiation. Also functions as part of the RQC trigger (RQT) complex that activates the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UYD4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0180022 RQC-trigger complex", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0061055 myotome development;GO:0007409 axonogenesis;GO:0007528 neuromuscular junction development;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IR18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IR31-1", "uniprot_id": [ { "id": "A0A0R4IR31_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IR31", "type": "external" } ], "mass": 28414.0, "length": 250, "protein_name": "Uncharacterized protein LOC103911540 precursor; Zgc:103700", "gene_name": "mhc2dhb", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC103911540 precursor", "refseq_ac": [ { "id": "NP_001005943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005943", "type": "external" } ], "gene_names_uniprotkb": "mhc2dhb; zgc:103700", "gene_names_refseq": "mhc2dhb; zgc:103700", "protein_names_uniprotkb": "Uncharacterized protein LOC103911540 precursor; Zgc:103700", "protein_names_refseq": "H-2 class II histocompatibility antigen, E-S beta chain-like; MHCII; uncharacterized protein LOC103911540 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:103911540); (R-DRE-2132295)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "23594743;25219565;25956722;26509227;27084059;27189481;30833947;31057394;31678534;32390373;34262881", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01045080.1, BC083466.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH452369.1, EH465241.1 and JBMGRA010000008.1. On or before Mar 29, 2018 this sequence version replaced XP_009302405.1, NP_001005943.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BBY8", "ec_number_list": [], "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex", "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation;GO:0050778 positive regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IR31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IR84-1", "uniprot_id": [ { "id": "A0A0R4IR84_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IR84", "type": "external" } ], "mass": 101606.0, "length": 886, "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "gene_name": "ndst1b", "organism": "Zebrafish", "refseq_name": "bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1b", "refseq_ac": [ { "id": "NP_001311384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001311384", "type": "external" } ], "gene_names_uniprotkb": "ndst1b; fj47c03; ndst1; wu:fj47c03", "gene_names_refseq": "fj47c03; ndst1b; ndst1; wu:fj47c03", "protein_names_uniprotkb": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; 2.8.2.8; Glucosaminyl N-deacetylase/N-sulfotransferase 1", "protein_names_refseq": "N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1b", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal recessive intellectual developmental disorder 46 (Disease Ontology:DOID:0081210); intellectual disability (Disease Ontology:DOID:1059); DiGeorge syndrome (Disease Ontology:DOID:11198); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); azoospermia (Disease Ontology:DOID:14227); germ cell cancer (Disease Ontology:DOID:2994); congenital diaphragmatic hernia (Disease Ontology:DOID:3827)", "pathway": " (dre:570459); (R-DRE-2022928)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "19858418;23594743;24643020;25767878;27189481;31269894;33068391;36503154", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01024377.1, SRR26395039.1759821.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IP80;A0A8M1P7R8", "ec_number_list": [ { "id": "2.8.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.8", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0019213 deacetylase activity;GO:0015016 heparan sulfate N-sulfotransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0051923 sulfation;GO:0001570 vasculogenesis;GO:0030210 heparin proteoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IR84-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IR92-1", "uniprot_id": [ { "id": "A0A0R4IR92_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IR92", "type": "external" } ], "mass": 42661.0, "length": 380, "protein_name": "Dopamine receptor D4a", "gene_name": "drd4a", "organism": "Zebrafish", "refseq_name": "dopamine receptor D4a", "refseq_ac": [ { "id": "NP_001012634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012634", "type": "external" } ], "gene_names_uniprotkb": "drd4a; zgc:158147", "gene_names_refseq": "drd4a; zgc:158147", "protein_names_uniprotkb": "Dopamine receptor D4a", "protein_names_refseq": "dopamine D4a receptor; dopamine receptor D4a", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); pervasive developmental disorder (Disease Ontology:DOID:0060040); intellectual disability (Disease Ontology:DOID:1059); Alzheimer's disease (Disease Ontology:DOID:10652); antisocial personality disorder (Disease Ontology:DOID:10939); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); Gilles de la Tourette syndrome (Disease Ontology:DOID:11119); opioid abuse (Disease Ontology:DOID:11206); pathological gambling (Disease Ontology:DOID:12399); conduct disorder (Disease Ontology:DOID:12995); alcohol use disorder (Disease Ontology:DOID:1574); substance abuse (Disease Ontology:DOID:302); dyslexia (Disease Ontology:DOID:4428); liver cirrhosis (Disease Ontology:DOID:5082); schizophrenia (Disease Ontology:DOID:5419); cannabis abuse (Disease Ontology:DOID:9505); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dre:503564)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16764679;22207143;22313674;23594743;23707737;26674873;35370746;35595013;35710785;35905303;36936688", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC129139.1, AY750152.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC129139.1 and JBMGRA010000025.1. On Dec 4, 2015 this sequence version replaced NP_001012634.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N4C0", "ec_number_list": [], "go_molecular_function": "GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930 G protein-coupled receptor activity;GO:0004938 alpha2-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0060158 phospholipase C-activating dopamine receptor signaling pathway;GO:0021520 spinal cord motor neuron cell fate specification;GO:0014059 regulation of dopamine secretion;GO:0051967 negative regulation of synaptic transmission, glutamatergic;GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IR92-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRA3-1", "uniprot_id": [ { "id": "A0A0R4IRA3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRA3", "type": "external" } ], "mass": 21069.0, "length": 193, "protein_name": "Protein lin-28 homolog A", "gene_name": "lin28aa", "organism": "Zebrafish", "refseq_name": "protein lin-28 homolog A isoform X1", "refseq_ac": [ { "id": "XP_017206944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206944", "type": "external" } ], "gene_names_uniprotkb": "lin28aa", "gene_names_refseq": "lin28aa", "protein_names_uniprotkb": "Protein lin-28 homolog A", "protein_names_refseq": "protein lin-28 homolog A isoform X1", "tax_id": 7955, "disease": "nephroblastoma (Disease Ontology:DOID:2154)", "pathway": " (dre:799825)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YSU1", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005791 rough endoplasmic reticulum;GO:0000932 P-body", "go_biological_process": "GO:0031054 pre-miRNA processing;GO:0031047 regulatory ncRNA-mediated gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRA3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRA8-1", "uniprot_id": [ { "id": "A0A0R4IRA8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRA8", "type": "external" } ], "mass": 31702.0, "length": 277, "protein_name": "Si:dkey-33b17.3; Uncharacterized protein LOC563286", "gene_name": "mhc2d8.35b2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC563286", "refseq_ac": [ { "id": "NP_001074102", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074102", "type": "external" } ], "gene_names_uniprotkb": "mhc2d8.35b2; si:busm1-160c18.3; si:dkey-33b17.3; si:dz160c18.3; zgc:158775", "gene_names_refseq": "mhc2d8.35b2; si:busm1-160c18.3; si:dkey-33b17.3; si:dz160c18.3; zgc:158775", "protein_names_uniprotkb": "Si:dkey-33b17.3; Uncharacterized protein LOC563286", "protein_names_refseq": "MHC class II; beta chain; uncharacterized protein LOC563286", "tax_id": 7955, "disease": "", "pathway": " (dre:563286); (R-DRE-2132295)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "22805612;23594743;24279922;27189481;35134499", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC129443.1, GFIL01035288.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On or before Jun 4, 2016 this sequence version replaced XP_009302403.1, NP_001074102.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UYL8", "ec_number_list": [], "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex", "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation;GO:0050778 positive regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IRA8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRB0-1", "uniprot_id": [ { "id": "A0A0R4IRB0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRB0", "type": "external" } ], "mass": 18396.0, "length": 164, "protein_name": "Uncharacterized protein LOC560551; Uncharacterized protein isoform X1; Wu:fa19b12", "gene_name": "fa19b12", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC560551", "refseq_ac": [ { "id": "NP_001268914", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268914", "type": "external" } ], "gene_names_uniprotkb": "fa19b12; wu:fa19b12", "gene_names_refseq": "fa19b12; wu:fa19b12", "protein_names_uniprotkb": "Uncharacterized protein LOC560551; Uncharacterized protein isoform X1; Wu:fa19b12", "protein_names_refseq": "uncharacterized protein LOC560551", "tax_id": 7955, "disease": "", "pathway": " (dre:560551)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CT668423.2, CT658784.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jul 8, 2025 this sequence version replaced NP_001268914.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P052", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IRB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRB9-1", "uniprot_id": [ { "id": "A0A0R4IRB9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRB9", "type": "external" } ], "mass": 33114.0, "length": 290, "protein_name": "Calcium-activated potassium channel subunit beta-3; Si:ch211-38m6.7", "gene_name": "kcnmb3", "organism": "Zebrafish", "refseq_name": "calcium-activated potassium channel subunit beta-3 isoform X1", "refseq_ac": [ { "id": "XP_009295878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295878", "type": "external" } ], "gene_names_uniprotkb": "kcnmb3; si:ch211-38m6.7", "gene_names_refseq": "kcnmb3", "protein_names_uniprotkb": "Calcium-activated potassium channel subunit beta-3; Si:ch211-38m6.7", "protein_names_refseq": "calcium-activated potassium channel subunit beta-3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101885585); (R-DRE-1296052)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B6U5", "ec_number_list": [], "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0015269 calcium-activated potassium channel activity", "go_cellular_component": "GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:0005513 detection of calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRC7-1", "uniprot_id": [ { "id": "A0A0R4IRC7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRC7", "type": "external" } ], "mass": 69728.0, "length": 620, "protein_name": "AVL9 homolog (S. cerevisiase); Late secretory pathway protein AVL9 homolog isoform 2", "gene_name": "avl9", "organism": "Zebrafish", "refseq_name": "late secretory pathway protein AVL9 homolog isoform 2", "refseq_ac": [ { "id": "NP_001314759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314759", "type": "external" } ], "gene_names_uniprotkb": "avl9; zgc:153609", "gene_names_refseq": "avl9; zgc:153609", "protein_names_uniprotkb": "AVL9 homolog (S. cerevisiase); Late secretory pathway protein AVL9 homolog isoform 2", "protein_names_refseq": "late secretory pathway protein AVL9 homolog isoform 2", "tax_id": 7955, "disease": "", "pathway": " (dre:751682)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26469318;27784263;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588731.2467070.1, SRR32588725.29127538.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On May 26, 2016 this sequence version replaced XP_005156138.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P335", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IRC7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRC9-1", "uniprot_id": [ { "id": "A0A0R4IRC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRC9", "type": "external" } ], "mass": 37186.0, "length": 330, "protein_name": "Si:dkey-245n4.2", "gene_name": "si:dkey-245n4.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-245n4.2", "refseq_ac": [ { "id": "XP_005165491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165491", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-245n4.2", "gene_names_refseq": "si:dkey-245n4.2", "protein_names_uniprotkb": "Si:dkey-245n4.2", "protein_names_refseq": "uncharacterized protein si:dkey-245n4.2", "tax_id": 7955, "disease": "", "pathway": " (dre:101886647)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BCT8;A0A8M9QEU9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRF0-1", "uniprot_id": [ { "id": "A0A0R4IRF0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRF0", "type": "external" } ], "mass": 47039.0, "length": 402, "protein_name": "Tektin", "gene_name": "tekt1", "organism": "Zebrafish", "refseq_name": "tektin-1", "refseq_ac": [ { "id": "NP_001007398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007398", "type": "external" } ], "gene_names_uniprotkb": "tekt1; zgc:101797", "gene_names_refseq": "tekt1; zgc:101797", "protein_names_uniprotkb": "Tektin", "protein_names_refseq": "tektin-1", "tax_id": 7955, "disease": "ciliopathy (Disease Ontology:DOID:0060340)", "pathway": " (dre:492525)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "18335061;19011630;20937855;23144623;23594743;27357367;28738802;29121203;31513014", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC085442.1, GDQH01026266.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 28, 2024 this sequence version replaced NP_001007398.1., [RefSeq]; Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ASX1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0015630 microtubule cytoskeleton;GO:0005930 axoneme", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IRF0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRJ2-1", "uniprot_id": [ { "id": "A0A0R4IRJ2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRJ2", "type": "external" } ], "mass": 38433.0, "length": 339, "protein_name": "inorganic diphosphatase", "gene_name": "ppa2", "organism": "Zebrafish", "refseq_name": "inorganic pyrophosphatase 2, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_005159941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159941", "type": "external" } ], "gene_names_uniprotkb": "ppa2; zgc:77715", "gene_names_refseq": "ppa2; zgc:77715", "protein_names_uniprotkb": "inorganic diphosphatase; 3.6.1.1", "protein_names_refseq": "inorganic pyrophosphatase 2, mitochondrial isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:402961); (R-DRE-379716); (R-DRE-71737)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "23594743;24396069;26469318;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B720", "ec_number_list": [ { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004427 inorganic diphosphate phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006796 phosphate-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IRJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRJ4-1", "uniprot_id": [ { "id": "A0A0R4IRJ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRJ4", "type": "external" } ], "mass": 273169.0, "length": 2532, "protein_name": "Proline-rich 12a; Proline-rich protein 12 isoform X1", "gene_name": "prr12a", "organism": "Zebrafish", "refseq_name": "proline-rich protein 12 isoform X1", "refseq_ac": [ { "id": "XP_005156071", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156071", "type": "external" } ], "gene_names_uniprotkb": "prr12a", "gene_names_refseq": "prr12a", "protein_names_uniprotkb": "Proline-rich 12a; Proline-rich protein 12 isoform X1", "protein_names_refseq": "proline-rich protein 12 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:564766)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B2W6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRM1-1", "uniprot_id": [ { "id": "A0A0R4IRM1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRM1", "type": "external" } ], "mass": 109021.0, "length": 959, "protein_name": "Kinesin-like protein", "gene_name": "kif5ba; kif5bb", "organism": "Zebrafish", "refseq_name": "kinesin-1 heavy chain", "refseq_ac": [ { "id": "XP_002664065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664065", "type": "external" } ], "gene_names_uniprotkb": "kif5ba; kif5bb; kif5ba", "gene_names_refseq": "kif5bb", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-1 heavy chain", "tax_id": 7955, "disease": "spinal muscular atrophy (Disease Ontology:DOID:12377); neurodegenerative disease (Disease Ontology:DOID:1289); motor neuron disease (Disease Ontology:DOID:231); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (dre:334108); (dre:563459)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHK3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0016887 ATP hydrolysis activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule;GO:0005737 cytoplasm;GO:0005871 kinesin complex;GO:0032839 dendrite cytoplasm", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0060349 bone morphogenesis;GO:0007281 germ cell development;GO:0051216 cartilage development;GO:0007519 skeletal muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRM1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRM6-1", "uniprot_id": [ { "id": "A0A0R4IRM6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRM6", "type": "external" } ], "mass": 14392.0, "length": 128, "protein_name": "Fatty acid binding protein 1-B.1; Fatty acid-binding protein 1b, liver, tandem duplicate 2", "gene_name": "fabp1b.2", "organism": "Zebrafish", "refseq_name": "fatty acid binding protein 1-B.1", "refseq_ac": [ { "id": "XP_002663094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663094", "type": "external" } ], "gene_names_uniprotkb": "fabp1b.2", "gene_names_refseq": "fabp1b.2", "protein_names_uniprotkb": "Fatty acid binding protein 1-B.1; Fatty acid-binding protein 1b, liver, tandem duplicate 2", "protein_names_refseq": "fatty acid binding protein 1-B.1", "tax_id": 7955, "disease": "hypertension (Disease Ontology:DOID:10763); IgA glomerulonephritis (Disease Ontology:DOID:2986)", "pathway": " (dre:100330224)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_002663094.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RKB8", "ec_number_list": [], "go_molecular_function": "GO:0005504 fatty acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0015908 fatty acid transport;GO:0033993 response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRM6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRN2-1", "uniprot_id": [ { "id": "A0A0R4IRN2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRN2", "type": "external" } ], "mass": 101880.0, "length": 908, "protein_name": "Glutamate receptor, metabotropic 6a isoform X1; Metabotropic glutamate receptor 6a", "gene_name": "grm6a", "organism": "Zebrafish", "refseq_name": "glutamate receptor, metabotropic 6a isoform X1", "refseq_ac": [ { "id": "XP_021333966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333966", "type": "external" } ], "gene_names_uniprotkb": "grm6a; si:dkey-52h10.3", "gene_names_refseq": "grm6a; si:dkey-52h10.3", "protein_names_uniprotkb": "Glutamate receptor, metabotropic 6a isoform X1; Metabotropic glutamate receptor 6a", "protein_names_refseq": "glutamate receptor, metabotropic 6a isoform X1", "tax_id": 7955, "disease": "congenital stationary night blindness 1B (Disease Ontology:DOID:0110865)", "pathway": " (dre:568484); (R-DRE-418594); (R-DRE-420499)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "16229975;22523578;23047810;23594743;26818140;27189481;28252024;34329618", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0051966 regulation of synaptic transmission, glutamatergic;GO:0007216 G protein-coupled glutamate receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IRN2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRN4-1", "uniprot_id": [ { "id": "A0A0R4IRN4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRN4", "type": "external" } ], "mass": 29361.0, "length": 271, "protein_name": "Collectin-10 precursor; Si:ch211-93i7.4", "gene_name": "si:ch211-93i7.4", "organism": "Zebrafish", "refseq_name": "collectin-10 precursor", "refseq_ac": [ { "id": "NP_001276917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001276917", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-93i7.4; colec10", "gene_names_refseq": "colec10; si:ch211-93i7.4", "protein_names_uniprotkb": "Collectin-10 precursor; Si:ch211-93i7.4", "protein_names_refseq": "collectin-10 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:794040); (R-DRE-166662)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01024808.1, AI353438.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_001276917.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P5C7", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005581 collagen trimer", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IRN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRQ0-1", "uniprot_id": [ { "id": "A0A0R4IRQ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRQ0", "type": "external" } ], "mass": 66002.0, "length": 583, "protein_name": "EF-hand and coiled-coil domain-containing protein 1 isoform X1; Si:ch211-112f3.4", "gene_name": "si:ch211-112f3.4", "organism": "Zebrafish", "refseq_name": "EF-hand and coiled-coil domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_021335565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335565", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-112f3.4", "gene_names_refseq": "si:ch211-112f3.4", "protein_names_uniprotkb": "EF-hand and coiled-coil domain-containing protein 1 isoform X1; Si:ch211-112f3.4", "protein_names_refseq": "EF-hand and coiled-coil domain-containing protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:793893)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QM40", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRS1-1", "uniprot_id": [ { "id": "A0A0R4IRS1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRS1", "type": "external" } ], "mass": 48562.0, "length": 423, "protein_name": "AP-1 complex subunit mu-1", "gene_name": "ap1m1", "organism": "Zebrafish", "refseq_name": "AP-1 complex subunit mu-1", "refseq_ac": [ { "id": "NP_001318056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001318056", "type": "external" } ], "gene_names_uniprotkb": "ap1m1", "gene_names_refseq": "ap1m1", "protein_names_uniprotkb": "AP-1 complex subunit mu-1", "protein_names_refseq": "AP-1 complex subunit mu-1; adaptor-related protein complex 1, mu 1 subunit", "tax_id": 7955, "disease": "", "pathway": " (dre:100330411); (R-DRE-2132295); (R-DRE-432720); (R-DRE-6798695)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "20652956;23594743;24123392;26469318;28557307", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019957.1, SRR26395063.820717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P5E7", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0030136 clathrin-coated vesicle;GO:0030665 clathrin-coated vesicle membrane;GO:0005802 trans-Golgi network;GO:0030131 clathrin adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007420 brain development;GO:0016192 vesicle-mediated transport;GO:0048565 digestive tract development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IRS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRS4-1", "uniprot_id": [ { "id": "A0A0R4IRS4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRS4", "type": "external" } ], "mass": 65477.0, "length": 588, "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "pnkp", "organism": "Zebrafish", "refseq_name": "bifunctional polynucleotide phosphatase/kinase isoform X1", "refseq_ac": [ { "id": "XP_005173439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173439", "type": "external" } ], "gene_names_uniprotkb": "pnkp; fe48d04; wu:fe48d04; zgc:153084", "gene_names_refseq": "fe48d04; pnkp; wu:fe48d04; zgc:153084", "protein_names_uniprotkb": "Bifunctional polynucleotide phosphatase/kinase; 2.7.1.78; 3.1.3.32; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase", "protein_names_refseq": "bifunctional polynucleotide phosphatase/kinase isoform X1", "tax_id": 7955, "disease": "microcephaly, seizures, and developmental delay (Disease Ontology:DOID:0080457); ataxia-oculomotor apraxia type 4 (Disease Ontology:DOID:0081383); Charcot-Marie-Tooth disease type 2B2 (Disease Ontology:DOID:0110179)", "pathway": " (dre:569462); (R-DRE-5649702)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKP4", "ec_number_list": [ { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "3.1.3.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" } ], "go_molecular_function": "GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0046403 polynucleotide 3'-phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IRS4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRT8-1", "uniprot_id": [ { "id": "A0A0R4IRT8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRT8", "type": "external" } ], "mass": 111418.0, "length": 1003, "protein_name": "Uncharacterized protein LOC566129; Zgc:153345", "gene_name": "zgc:153345", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC566129", "refseq_ac": [ { "id": "NP_001071081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071081", "type": "external" } ], "gene_names_uniprotkb": "zgc:153345", "gene_names_refseq": "zgc:153345", "protein_names_uniprotkb": "Uncharacterized protein LOC566129; Zgc:153345", "protein_names_refseq": "uncharacterized protein LOC566129", "tax_id": 7955, "disease": "", "pathway": " (dre:566129)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC125864.1, GFIL01045210.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On or before Sep 1, 2015 this sequence version replaced XP_005172733.1, NP_001071081.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1YXS7", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IRT8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRU6-1", "uniprot_id": [ { "id": "A0A0R4IRU6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRU6", "type": "external" } ], "mass": 84176.0, "length": 752, "protein_name": "Rho GTPase-activating protein 24", "gene_name": "arhgap24", "organism": "Zebrafish", "refseq_name": "rho GTPase-activating protein 24 isoform X1", "refseq_ac": [ { "id": "XP_001339010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339010", "type": "external" } ], "gene_names_uniprotkb": "arhgap24", "gene_names_refseq": "arhgap24", "protein_names_uniprotkb": "Rho GTPase-activating protein 24; Rho-type GTPase-activating protein 24", "protein_names_refseq": "rho GTPase-activating protein 24 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100005116); (R-DRE-8980692); (R-DRE-9013148); (R-DRE-9013149)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001339010.1. COMPLETENESS: full length., [RefSeq]; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PUP4", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0042995 cell projection", "go_biological_process": "GO:0007165 signal transduction;GO:0051056 regulation of small GTPase mediated signal transduction;GO:1900028 negative regulation of ruffle assembly;GO:0030154 cell differentiation;GO:0035313 wound healing, spreading of epidermal cells", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRV6-1", "uniprot_id": [ { "id": "A0A0R4IRV6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRV6", "type": "external" } ], "mass": 37897.0, "length": 335, "protein_name": "Transcription factor AP-4 (activating enhancer-binding protein 4); Transcription factor AP-4 isoform X1", "gene_name": "tfap4", "organism": "Zebrafish", "refseq_name": "transcription factor AP-4 isoform X1", "refseq_ac": [ { "id": "XP_005168526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168526", "type": "external" } ], "gene_names_uniprotkb": "tfap4", "gene_names_refseq": "tfap4", "protein_names_uniprotkb": "Transcription factor AP-4 (activating enhancer-binding protein 4); Transcription factor AP-4 isoform X1", "protein_names_refseq": "transcription factor AP-4 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100318080)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BFS3", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IRV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRW2-1", "uniprot_id": [ { "id": "A0A0R4IRW2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRW2", "type": "external" } ], "mass": 8551.0, "length": 76, "protein_name": "Calcium/calmodulin-dependent protein kinase II inhibitor 2-like; Si:dkey-33m11.6", "gene_name": "camk2n1a", "organism": "Zebrafish", "refseq_name": "Calcium/calmodulin-dependent protein kinase II inhibitor 2-like", "refseq_ac": [ { "id": "NP_001186929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186929", "type": "external" } ], "gene_names_uniprotkb": "camk2n1a; camk2n1; si:dkey-33m11.6", "gene_names_refseq": "camk2n1a; camk2n1; si:dkey-33m11.6", "protein_names_uniprotkb": "Calcium/calmodulin-dependent protein kinase II inhibitor 2-like; Si:dkey-33m11.6", "protein_names_refseq": "Calcium/calmodulin-dependent protein kinase II inhibitor 2-like; calcium/calmodulin dependent protein kinase II inhibitor 1", "tax_id": 7955, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); prostate cancer (Disease Ontology:DOID:10283); ovarian cancer (Disease Ontology:DOID:2394); prostate adenocarcinoma (Disease Ontology:DOID:2526); papillary thyroid carcinoma (Disease Ontology:DOID:3969); ovarian carcinoma (Disease Ontology:DOID:4001); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:555986)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC135037.1, GFIL01022808.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NV62", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0008427 calcium-dependent protein kinase inhibitor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IRW2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRW8-1", "uniprot_id": [ { "id": "A0A0R4IRW8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRW8", "type": "external" } ], "mass": 68312.0, "length": 654, "protein_name": "Zgc:100868", "gene_name": "im:7038378", "organism": "Zebrafish", "refseq_name": "zgc:100868 precursor", "refseq_ac": [ { "id": "NP_001003526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003526", "type": "external" } ], "gene_names_uniprotkb": "im:7038378; fc74e04; im:7144259; wu:fc74e04; zgc:100868", "gene_names_refseq": "fc74e04; im:7038378; im:7144259; wu:fc74e04; zgc:100868", "protein_names_uniprotkb": "Zgc:100868", "protein_names_refseq": "zgc:100868 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:554458)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;33826923", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01044106.1, SRR26395013.503504.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On or before Jun 24, 2024 this sequence version replaced XP_005164187.1, NP_001003526.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBA2", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IRW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IRX2-1", "uniprot_id": [ { "id": "A0A0R4IRX2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IRX2", "type": "external" } ], "mass": 10773.0, "length": 94, "protein_name": "C-C motif chemokine", "gene_name": "ccl27a", "organism": "Zebrafish", "refseq_name": "C-C motif chemokine 27a isoform 2 precursor", "refseq_ac": [ { "id": "NP_001315310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315310", "type": "external" } ], "gene_names_uniprotkb": "ccl27a; ccl1; wu:fa96a04", "gene_names_refseq": "ccl1; ccl27a; wu:fa96a04", "protein_names_uniprotkb": "C-C motif chemokine", "protein_names_refseq": "C-C motif chemokine 27a isoform 2 precursor; CC chemokine 1; Dr18_WGA1436_1_236332; Dr8_WGA606_1_66363", "tax_id": 7955, "disease": "COVID-19 (Disease Ontology:DOID:0080600); asthma (Disease Ontology:DOID:2841); atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": " (dre:30268)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16365434;16697551;18482437;18784347;19084604;23594743;26469318;26851375;29247975;29554508;29760055", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH445572.1, EH467394.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH452920.1 and EH445572.1. On Jun 16, 2016 this sequence version replaced XP_005166726.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9V0", "ec_number_list": [], "go_molecular_function": "GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IRX2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS14-1", "uniprot_id": [ { "id": "A0A0R4IS14_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS14", "type": "external" } ], "mass": 345801.0, "length": 3065, "protein_name": "Wu:fj29h11", "gene_name": "wu:fj29h11", "organism": "Zebrafish", "refseq_name": "uncharacterized protein wu:fj29h11 isoform X1", "refseq_ac": [ { "id": "XP_009304641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304641", "type": "external" } ], "gene_names_uniprotkb": "wu:fj29h11", "gene_names_refseq": "wu:fj29h11", "protein_names_uniprotkb": "Wu:fj29h11", "protein_names_refseq": "uncharacterized protein wu:fj29h11 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:335618)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B4C4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IS14-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS19-1", "uniprot_id": [ { "id": "A0A0R4IS19_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS19", "type": "external" } ], "mass": 94362.0, "length": 830, "protein_name": "SLIT and NTRK-like family, member 6; SLIT and NTRK-like protein 6 precursor", "gene_name": "slitrk6", "organism": "Zebrafish", "refseq_name": "SLIT and NTRK-like protein 6 precursor", "refseq_ac": [ { "id": "NP_001292482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292482", "type": "external" } ], "gene_names_uniprotkb": "slitrk6; wu:fc18f06", "gene_names_refseq": "slitrk6; wu:fc18f06", "protein_names_uniprotkb": "SLIT and NTRK-like family, member 6; SLIT and NTRK-like protein 6 precursor", "protein_names_refseq": "SLIT and NTRK-like protein 6 precursor; slit and trk like 6", "tax_id": 7955, "disease": "high myopia-sensorineural deafness syndrome (Disease Ontology:DOID:0111628)", "pathway": " (dre:324096)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;24123428;26492970", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01043565.1, GDQH01017447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Mar 18, 2015 this sequence version replaced XP_003197659.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1A6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007409 axonogenesis;GO:0051965 positive regulation of synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IS19-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS21-1", "uniprot_id": [ { "id": "A0A0R4IS21_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS21", "type": "external" } ], "mass": 165020.0, "length": 1465, "protein_name": "Si:dkey-238i5.2", "gene_name": "si:dkey-238i5.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-238i5.2 isoform X1", "refseq_ac": [ { "id": "XP_003199551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199551", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-238i5.2", "gene_names_refseq": "si:dkey-238i5.2", "protein_names_uniprotkb": "Si:dkey-238i5.2", "protein_names_refseq": "uncharacterized protein si:dkey-238i5.2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:321155)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003199551.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RNP3", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0030864 cortical actin cytoskeleton;GO:0042995 cell projection", "go_biological_process": "GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IS21-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "uniprot_id": [ { "id": "A0A0R4IS27_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS27", "type": "external" } ], "mass": 93682.0, "length": 837, "protein_name": "Olfactory receptor C family, g6; Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "organism": "Zebrafish", "refseq_name": "olfactory receptor CG6", "refseq_ac": [ { "id": "NP_001153313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153313", "type": "external" } ], "gene_names_uniprotkb": "olfcg6; A12; Dr9-10; si:dkey-74e13.1; v2ra12", "gene_names_refseq": "A12; Dr9-10; olfcg6; si:dkey-74e13.1; v2ra12", "protein_names_uniprotkb": "Olfactory receptor C family, g6; Olfactory receptor CG6 precursor", "protein_names_refseq": "olfactory receptor CG6; sub 9_2", "tax_id": 7955, "disease": "", "pathway": " (dre:100149406)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.2808682.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505382 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On May 8, 2009 this sequence version replaced XP_001919175.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUI9", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IS27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS36-1", "uniprot_id": [ { "id": "A0A0R4IS36_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS36", "type": "external" } ], "mass": 44385.0, "length": 397, "protein_name": "Endophilin-B1", "gene_name": "sh3glb1b", "organism": "Zebrafish", "refseq_name": "endophilin-B1b isoform X1", "refseq_ac": [ { "id": "XP_005163364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163364", "type": "external" } ], "gene_names_uniprotkb": "sh3glb1b; im:5777505; sh3glb1; wu:fa08f03; wu:fb13e12", "gene_names_refseq": "im:5777505; sh3glb1b; sh3glb1; wu:fa08f03; wu:fb13e12", "protein_names_uniprotkb": "Endophilin-B1; SH3 domain-containing GRB2-like protein B1", "protein_names_refseq": "endophilin-B1b isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:334911)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16109975;16448862;23594743;26469318;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BAQ1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IS36-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS41-1", "uniprot_id": [ { "id": "A0A0R4IS41_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS41", "type": "external" } ], "mass": 33732.0, "length": 294, "protein_name": "C2H2-type zinc finger protein; Gastrula zinc finger protein XlCGF7.1; Si:ch211-241b2.4", "gene_name": "si:ch211-241b2.4", "organism": "Zebrafish", "refseq_name": "C2H2-type zinc finger protein", "refseq_ac": [ { "id": "NP_001373223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373223", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-241b2.4", "gene_names_refseq": "si:ch211-241b2.4", "protein_names_uniprotkb": "C2H2-type zinc finger protein; Gastrula zinc finger protein XlCGF7.1; Si:ch211-241b2.4", "protein_names_refseq": "C2H2-type zinc finger protein", "tax_id": 7955, "disease": "", "pathway": " (dre:100150909)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH539915.1, GFIL01036159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476776 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 18, 2020 this sequence version replaced XP_001922865.4., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QLN9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IS41-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS45-1", "uniprot_id": [ { "id": "A0A0R4IS45_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS45", "type": "external" } ], "mass": 73435.0, "length": 654, "protein_name": "Conserved oligomeric Golgi complex subunit 6", "gene_name": "cog6", "organism": "Zebrafish", "refseq_name": "conserved oligomeric Golgi complex subunit 6", "refseq_ac": [ { "id": "NP_001307276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307276", "type": "external" } ], "gene_names_uniprotkb": "cog6; si:ch211-203f4.1; zgc:56117", "gene_names_refseq": "cog6; si:ch211-203f4.1; zgc:56117", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 6; COG complex subunit 6; Component of oligomeric Golgi complex 6", "protein_names_refseq": "conserved oligomeric Golgi complex subunit 6", "tax_id": 7955, "disease": "congenital disorder of glycosylation type IIl (Disease Ontology:DOID:0070264)", "pathway": " (dre:393290); (R-DRE-6807878); (R-DRE-6811438)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "23594743;27189481;30905685", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01021752.1, GDQH01008234.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH587218.1, JBMGRA010000015.1 and EH587636.1. On Feb 20, 2016 this sequence version replaced XP_005157440.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Required for normal Golgi function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2Y8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IS45-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS55-1", "uniprot_id": [ { "id": "A0A0R4IS55_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS55", "type": "external" } ], "mass": 56804.0, "length": 505, "protein_name": "Ankyrin repeat domain-containing protein SOWAHC; Sosondowah ankyrin repeat domain family Ca", "gene_name": "sowahca", "organism": "Zebrafish", "refseq_name": "ankyrin repeat domain-containing protein SOWAHC", "refseq_ac": [ { "id": "XP_009303301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303301", "type": "external" } ], "gene_names_uniprotkb": "sowahca", "gene_names_refseq": "sowahca", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein SOWAHC; Sosondowah ankyrin repeat domain family Ca", "protein_names_refseq": "ankyrin repeat domain-containing protein SOWAHC", "tax_id": 7955, "disease": "", "pathway": " (dre:100321117); (R-DRE-8980692); (R-DRE-9013026); (R-DRE-9035034)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_009303301.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B5X3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IS55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS70-1", "uniprot_id": [ { "id": "A0A0R4IS70_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS70", "type": "external" } ], "mass": 34117.0, "length": 317, "protein_name": "Purine-rich element-binding protein Ba", "gene_name": "purba", "organism": "Zebrafish", "refseq_name": "purine-rich element binding protein Ba", "refseq_ac": [ { "id": "NP_001153631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153631", "type": "external" } ], "gene_names_uniprotkb": "purba; si:dkey-202n14.1", "gene_names_refseq": "purba; si:dkey-202n14.1", "protein_names_uniprotkb": "Purine-rich element-binding protein Ba", "protein_names_refseq": "purine-rich element binding protein B-like; purine-rich element binding protein Ba", "tax_id": 7955, "disease": "", "pathway": " (dre:565233)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: GFIL01023782.1, BC167481.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and BC167481.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUK6", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0032422 purine-rich negative regulatory element binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IS70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS83-1", "uniprot_id": [ { "id": "A0A0R4IS83_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS83", "type": "external" } ], "mass": 87516.0, "length": 797, "protein_name": "Periostin", "gene_name": "postnb", "organism": "Zebrafish", "refseq_name": "periostin, osteoblast specific factor b isoform X1", "refseq_ac": [ { "id": "XP_009290066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290066", "type": "external" } ], "gene_names_uniprotkb": "postnb; PN; fa99h07; pn; postn; wu:fa99h07; wu:fc70f09; zgc:153873", "gene_names_refseq": "fa99h07; pn; postnb; postn; wu:fa99h07; wu:fc70f09; zgc:153873", "protein_names_uniprotkb": "Periostin; Osteoblast-specific factor 2", "protein_names_refseq": "periostin, osteoblast specific factor b isoform X1", "tax_id": 7955, "disease": "bone structure disease (Disease Ontology:DOID:0080010); aggressive periodontitis (Disease Ontology:DOID:1474); congestive heart failure (Disease Ontology:DOID:6000); abdominal aortic aneurysm (Disease Ontology:DOID:7693); chronic kidney disease (Disease Ontology:DOID:784); degenerative disc disease (Disease Ontology:DOID:90)", "pathway": " (dre:337176)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "15013807;15376328;18248185;20179605;21468032;23594743;34887420;34988408;35013168;35088848;35324428", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AHK2", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0071307 cellular response to vitamin K;GO:0007155 cell adhesion;GO:0016203 muscle attachment;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IS83-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS85-1", "uniprot_id": [ { "id": "A0A0R4IS85_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS85", "type": "external" } ], "mass": 19393.0, "length": 176, "protein_name": "Glucagon a", "gene_name": "gcga", "organism": "Zebrafish", "refseq_name": "glucagon a isoform 1 precursor", "refseq_ac": [ { "id": "NP_001258699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258699", "type": "external" } ], "gene_names_uniprotkb": "gcga; gcg; glu; zgc:103616", "gene_names_refseq": "gcga; gcg; glu; zgc:103616", "protein_names_uniprotkb": "Glucagon a", "protein_names_refseq": "GLP-1; glucagon a isoform 1 precursor", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); prediabetes syndrome (Disease Ontology:DOID:11716)", "pathway": " (dre:494052)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10495291;11161572;11477692;11900460;23594743;35367205;35489565;36065184;36334626;36646689;9972283", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011279.1, EH445427.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505388 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NZU1", "ec_number_list": [], "go_molecular_function": "GO:0031769 glucagon receptor binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0042594 response to starvation;GO:0003323 type B pancreatic cell development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IS85-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS92-1", "uniprot_id": [ { "id": "A0A0R4IS92_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS92", "type": "external" } ], "mass": 62287.0, "length": 553, "protein_name": "Copine IVa; Copine-4", "gene_name": "cpne4a", "organism": "Zebrafish", "refseq_name": "copine-4", "refseq_ac": [ { "id": "XP_009290856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290856", "type": "external" } ], "gene_names_uniprotkb": "cpne4a", "gene_names_refseq": "cpne4a", "protein_names_uniprotkb": "Copine IVa; Copine-4", "protein_names_refseq": "copine-4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AIF6", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IS92-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IS95-1", "uniprot_id": [ { "id": "A0A0R4IS95_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IS95", "type": "external" } ], "mass": 19214.0, "length": 174, "protein_name": "Si:ch73-281i18.4; Uncharacterized protein LOC100318116", "gene_name": "si:ch73-281i18.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100318116", "refseq_ac": [ { "id": "NP_001352982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352982", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-281i18.4", "gene_names_refseq": "si:ch73-281i18.4", "protein_names_uniprotkb": "Si:ch73-281i18.4; Uncharacterized protein LOC100318116", "protein_names_refseq": "uncharacterized protein LOC100318116", "tax_id": 7955, "disease": "", "pathway": " (dre:100318116)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.5797320.1, SRR32588718.31000150.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Sep 21, 2018 this sequence version replaced XP_005173806.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLF8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IS95-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISD3-1", "uniprot_id": [ { "id": "A0A0R4ISD3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISD3", "type": "external" } ], "mass": 17644.0, "length": 155, "protein_name": "RING finger protein 122", "gene_name": "rnf122", "organism": "Zebrafish", "refseq_name": "RING finger protein 122", "refseq_ac": [ { "id": "NP_001314745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314745", "type": "external" } ], "gene_names_uniprotkb": "rnf122; si:ch1073-392o20.1", "gene_names_refseq": "rnf122; si:ch1073-392o20.1", "protein_names_uniprotkb": "RING finger protein 122", "protein_names_refseq": "RING finger protein 122", "tax_id": 7955, "disease": "", "pathway": " (dre:100329730)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01016539.1, EH594469.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505379 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000008.1. On May 26, 2016 this sequence version replaced XP_002663295.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May induce necrosis and apoptosis. May play a role in cell viability., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P329", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ISD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISE0-1", "uniprot_id": [ { "id": "A0A0R4ISE0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISE0", "type": "external" } ], "mass": 85687.0, "length": 775, "protein_name": "Major intrinsically disordered Notch2-binding receptor 1-like; Si:dkey-88e18.8", "gene_name": "minar1l", "organism": "Zebrafish", "refseq_name": "major intrinsically disordered Notch2-binding receptor 1-like", "refseq_ac": [ { "id": "XP_009291713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291713", "type": "external" } ], "gene_names_uniprotkb": "minar1l; si:dkey-88e18.8", "gene_names_refseq": "minar1l", "protein_names_uniprotkb": "Major intrinsically disordered Notch2-binding receptor 1-like; Si:dkey-88e18.8", "protein_names_refseq": "major intrinsically disordered Notch2-binding receptor 1-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AK97", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0032007 negative regulation of TOR signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISE0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISE6-1", "uniprot_id": [ { "id": "A0A0R4ISE6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISE6", "type": "external" } ], "mass": 24819.0, "length": 225, "protein_name": "Si:dkey-29h14.10", "gene_name": "si:dkey-29h14.10", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-29h14.10 isoform X1", "refseq_ac": [ { "id": "XP_001340673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340673", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-29h14.10", "gene_names_refseq": "si:dkey-29h14.10", "protein_names_uniprotkb": "Si:dkey-29h14.10", "protein_names_refseq": "uncharacterized protein si:dkey-29h14.10 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100006986)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q1W9", "ec_number_list": [], "go_molecular_function": "GO:0070513 death domain binding;GO:0002020 protease binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:2001235 positive regulation of apoptotic signaling pathway;GO:0030330 DNA damage response, signal transduction by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISE8-1", "uniprot_id": [ { "id": "A0A0R4ISE8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISE8", "type": "external" } ], "mass": 24695.0, "length": 211, "protein_name": "Suppressor of IKBKE 1", "gene_name": "im:6912630", "organism": "Zebrafish", "refseq_name": "suppressor of IKBKE 1 isoform X1", "refseq_ac": [ { "id": "XP_009295355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295355", "type": "external" } ], "gene_names_uniprotkb": "im:6912630; sike1", "gene_names_refseq": "sike1", "protein_names_uniprotkb": "Suppressor of IKBKE 1; Suppressor of IKK-epsilon", "protein_names_refseq": "suppressor of IKBKE 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:449731)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AVP9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISH8-1", "uniprot_id": [ { "id": "A0A0R4ISH8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISH8", "type": "external" } ], "mass": 29318.0, "length": 254, "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "LOC108182772", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC108182772", "gene_names_refseq": "", "protein_names_uniprotkb": "NAD(P)(+)--arginine ADP-ribosyltransferase; 2.4.2.31; Mono(ADP-ribosyl)transferase", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:108182772)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PLB4", "ec_number_list": [ { "id": "2.4.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.31", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity;GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISJ3-1", "uniprot_id": [ { "id": "A0A0R4ISJ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISJ3", "type": "external" } ], "mass": 109254.0, "length": 952, "protein_name": "5'-3' exoribonuclease", "gene_name": "xrn2", "organism": "Zebrafish", "refseq_name": "5'-3' exoribonuclease 2", "refseq_ac": [ { "id": "NP_001001944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001944", "type": "external" } ], "gene_names_uniprotkb": "xrn2; wu:fb38g12; wu:fj53d06; zgc:55717", "gene_names_refseq": "wu:fb38g12; wu:fj53d06; xrn2; zgc:55717", "protein_names_uniprotkb": "5'-3' exoribonuclease; 3.1.13.-", "protein_names_refseq": "5'-3' exoribonuclease 2", "tax_id": 7955, "disease": "adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung cancer (Disease Ontology:DOID:1324); leiomyosarcoma (Disease Ontology:DOID:1967)", "pathway": " (dre:321940)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21468032;23594743;27189481;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.1014815.1, SRR26395012.1333037.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jul 22, 2010 this sequence version replaced NP_001001944.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1MZQ7", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0004534 5'-3' RNA exonuclease activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0007283 spermatogenesis;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0006353 DNA-templated transcription termination", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4ISJ3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISP9-1", "uniprot_id": [ { "id": "A0A0R4ISP9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISP9", "type": "external" } ], "mass": 27812.0, "length": 238, "protein_name": "Si:ch1073-67j19.2; Uncharacterized protein LOC101882838 precursor", "gene_name": "teni.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC101882838 precursor", "refseq_ac": [ { "id": "NP_001314926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314926", "type": "external" } ], "gene_names_uniprotkb": "teni.2; si:ch1073-67j19.2", "gene_names_refseq": "si:ch1073-67j19.2; teni.2", "protein_names_uniprotkb": "Si:ch1073-67j19.2; Uncharacterized protein LOC101882838 precursor", "protein_names_refseq": "uncharacterized protein LOC101882838 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:101882838)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;36639393", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DR724026.1, GFIL01017185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jun 2, 2016 this sequence version replaced XP_009298357.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8M7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4ISP9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISQ3-1", "uniprot_id": [ { "id": "A0A0R4ISQ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISQ3", "type": "external" } ], "mass": 59103.0, "length": 525, "protein_name": "Cholinergic receptor, nicotinic, beta 4 (neuronal); Neuronal acetylcholine receptor subunit beta-4", "gene_name": "chrnb4", "organism": "Zebrafish", "refseq_name": "neuronal acetylcholine receptor subunit beta-4 isoform X1", "refseq_ac": [ { "id": "XP_696993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696993", "type": "external" } ], "gene_names_uniprotkb": "chrnb4", "gene_names_refseq": "chrnb4", "protein_names_uniprotkb": "Cholinergic receptor, nicotinic, beta 4 (neuronal); Neuronal acetylcholine receptor subunit beta-4", "protein_names_refseq": "neuronal acetylcholine receptor subunit beta-4 isoform X1", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); lung cancer (Disease Ontology:DOID:1324); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); lung small cell carcinoma (Disease Ontology:DOID:5409); cocaine abuse (Disease Ontology:DOID:809); oral cavity cancer (Disease Ontology:DOID:8618)", "pathway": " (R-DRE-629594); (R-DRE-629597); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_696993.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TBN6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0060084 synaptic transmission involved in micturition;GO:0095500 acetylcholine receptor signaling pathway;GO:0034220 monoatomic ion transmembrane transport;GO:0051899 membrane depolarization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISQ3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISV1-1", "uniprot_id": [ { "id": "A0A0R4ISV1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISV1", "type": "external" } ], "mass": 219593.0, "length": 2025, "protein_name": "HEAT repeat-containing protein 5B", "gene_name": "heatr5b", "organism": "Zebrafish", "refseq_name": "HEAT repeat-containing protein 5B", "refseq_ac": [ { "id": "XP_009305319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305319", "type": "external" } ], "gene_names_uniprotkb": "heatr5b", "gene_names_refseq": "heatr5b", "protein_names_uniprotkb": "HEAT repeat-containing protein 5B", "protein_names_refseq": "HEAT repeat-containing protein 5B", "tax_id": 7955, "disease": "", "pathway": " (dre:571772)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AYT6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0030136 clathrin-coated vesicle;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0008104 protein localization;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISV1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISV2-1", "uniprot_id": [ { "id": "A0A0R4ISV2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISV2", "type": "external" } ], "mass": 9953.0, "length": 87, "protein_name": "Chemokine (C-C motif) ligand 39, duplicate 2; Eotaxin isoform X1", "gene_name": "ccl39.2", "organism": "Zebrafish", "refseq_name": "eotaxin", "refseq_ac": [ { "id": "XP_003201459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201459", "type": "external" } ], "gene_names_uniprotkb": "ccl39.2", "gene_names_refseq": "ccl39.2", "protein_names_uniprotkb": "Chemokine (C-C motif) ligand 39, duplicate 2; Eotaxin isoform X1", "protein_names_refseq": "eotaxin", "tax_id": 7955, "disease": "", "pathway": " (dre:100332947)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RJM9", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response;GO:0030335 positive regulation of cell migration;GO:0007411 axon guidance;GO:0050930 induction of positive chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISV2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISV4-1", "uniprot_id": [ { "id": "A0A0R4ISV4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISV4", "type": "external" } ], "mass": 90925.0, "length": 802, "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "anapc2", "organism": "Zebrafish", "refseq_name": "anaphase-promoting complex subunit 2", "refseq_ac": [ { "id": "NP_001243675", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243675", "type": "external" } ], "gene_names_uniprotkb": "anapc2; si:ch73-203i15.5", "gene_names_refseq": "anapc2; si:ch73-203i15.5", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 2; Cyclosome subunit 2", "protein_names_refseq": "anaphase-promoting complex subunit 2", "tax_id": 7955, "disease": "aplastic anemia (Disease Ontology:DOID:12449); primary angle-closure glaucoma (Disease Ontology:DOID:1405); lung adenocarcinoma (Disease Ontology:DOID:3910); lung adenoma (Disease Ontology:DOID:5386); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (dre:100318335); (R-DRE-141430); (R-DRE-174048); (R-DRE-174084); (R-DRE-174154); (R-DRE-174178); (R-DRE-174184); (R-DRE-176407); (R-DRE-176408); (R-DRE-176409); (R-DRE-176412); (R-DRE-179409); (R-DRE-2467813); (R-DRE-2559582); (R-DRE-68867); (R-DRE-69017); (R-DRE-983168)", "pathway_count": 17, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01020877.1, SRR26395028.1285125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001243675.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NZ26", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0051301 cell division;GO:0070979 protein K11-linked ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISV4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ISY9-1", "uniprot_id": [ { "id": "A0A0R4ISY9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ISY9", "type": "external" } ], "mass": 77187.0, "length": 709, "protein_name": "ADP-ribosylation factor-binding protein GGA3 isoform X1; Golgi-associated, gamma adaptin ear-containing, ARF-binding protein 3b", "gene_name": "gga3b", "organism": "Zebrafish", "refseq_name": "ADP-ribosylation factor-binding protein GGA3 isoform X1", "refseq_ac": [ { "id": "XP_009297383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297383", "type": "external" } ], "gene_names_uniprotkb": "gga3b", "gene_names_refseq": "gga3b", "protein_names_uniprotkb": "ADP-ribosylation factor-binding protein GGA3 isoform X1; Golgi-associated, gamma adaptin ear-containing, ARF-binding protein 3b", "protein_names_refseq": "ADP-ribosylation factor-binding protein GGA3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334661); (R-DRE-8854214); (R-DRE-8875656)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AQM1", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0031901 early endosome membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034394 protein localization to cell surface;GO:0006893 Golgi to plasma membrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ISY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT00-1", "uniprot_id": [ { "id": "A0A0R4IT00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT00", "type": "external" } ], "mass": 37043.0, "length": 320, "protein_name": "Elongation of very long chain fatty acids protein 1", "gene_name": "elovl1b", "organism": "Zebrafish", "refseq_name": "elongation of very long chain fatty acids protein 1b", "refseq_ac": [ { "id": "NP_001315523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315523", "type": "external" } ], "gene_names_uniprotkb": "elovl1b; ELOVL1; wu:fj32h05; zgc:56567", "gene_names_refseq": "elovl1b; wu:fj32h05; zgc:56567", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 1; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1", "protein_names_refseq": "elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b; elongation of very long chain fatty acids protein 1b", "tax_id": 7955, "disease": "adrenoleukodystrophy (Disease Ontology:DOID:10588)", "pathway": " (dre:406725); (R-DRE-2046105); (R-DRE-2046106); (R-DRE-75876)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "22438865;23594743;24947308;27078170;27189481;33690217;34849471;36075325", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.1462979.1, SRR26395014.911988.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1, EH505140.1 and EH603421.1. On Jun 18, 2016 this sequence version replaced XP_009304163.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PF52", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001822 kidney development;GO:0030148 sphingolipid biosynthetic process;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IT00-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT01-1", "uniprot_id": [ { "id": "A0A0R4IT01_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT01", "type": "external" } ], "mass": 9717.0, "length": 83, "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2; NDUFA4 mitochondrial complex-associated-like 2a", "gene_name": "ndufa4l2a", "organism": "Zebrafish", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2", "refseq_ac": [ { "id": "XP_001342709", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001342709", "type": "external" } ], "gene_names_uniprotkb": "ndufa4l2a", "gene_names_refseq": "ndufa4l2a", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2; NDUFA4 mitochondrial complex-associated-like 2a", "protein_names_refseq": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2", "tax_id": 7955, "disease": "", "pathway": " (dre:100003066)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001342709.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PZM1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0045277 respiratory chain complex IV", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IT01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT02-1", "uniprot_id": [ { "id": "A0A0R4IT02_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT02", "type": "external" } ], "mass": 30554.0, "length": 281, "protein_name": "Tumor necrosis factor receptor superfamily member 9b precursor; Tumor necrosis factor receptor superfamily, member 9b", "gene_name": "tnfrsf9b", "organism": "Zebrafish", "refseq_name": "tumor necrosis factor receptor superfamily member 9b precursor", "refseq_ac": [ { "id": "NP_001313387", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313387", "type": "external" } ], "gene_names_uniprotkb": "tnfrsf9b; tnfrsf9", "gene_names_refseq": "tnfrsf9b; tnfrsf9", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 9b precursor; Tumor necrosis factor receptor superfamily, member 9b", "protein_names_refseq": "41BB; tumor necrosis factor receptor superfamily member 9b precursor; tumor necrosis factor receptor superfamily, member 9", "tax_id": 7955, "disease": "immunodeficiency 109 (Disease Ontology:DOID:0061078)", "pathway": " (dre:100151629)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19598108;23594743;35364135", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01036376.1, EE315494.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196788 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 18, 2016 this sequence version replaced XP_001923114.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3D0", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "", "go_biological_process": "GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IT02-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT36-1", "uniprot_id": [ { "id": "A0A0R4IT36_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT36", "type": "external" } ], "mass": 85744.0, "length": 791, "protein_name": "Junctophilin", "gene_name": "jph3b", "organism": "Zebrafish", "refseq_name": "junctophilin-3", "refseq_ac": [ { "id": "NP_001116174", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116174", "type": "external" } ], "gene_names_uniprotkb": "jph3b; fc26e06; jph3; si:ch211-255l14.9; wu:fc26e06", "gene_names_refseq": "fc26e06; jph3b; jph3; si:ch211-255l14.9; wu:fc26e06", "protein_names_uniprotkb": "Junctophilin", "protein_names_refseq": "junctophilin 3; junctophilin-3", "tax_id": 7955, "disease": "Huntington's disease-like 2 (Disease Ontology:DOID:0090104)", "pathway": " (dre:569861)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.23297900.1, SRR26395062.1122086.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000025.1. On Jun 5, 2025 this sequence version replaced NP_001116174.1., [RefSeq]; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NGP7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030314 junctional membrane complex", "go_biological_process": "GO:0048167 regulation of synaptic plasticity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IT36-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT40-1", "uniprot_id": [ { "id": "A0A0R4IT40_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT40", "type": "external" } ], "mass": 31470.0, "length": 288, "protein_name": "Si:ch211-286o17.1", "gene_name": "si:ch211-286o17.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-286o17.1", "refseq_ac": [ { "id": "XP_002662572", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662572", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-286o17.1", "gene_names_refseq": "si:ch211-286o17.1", "protein_names_uniprotkb": "Si:ch211-286o17.1", "protein_names_refseq": "uncharacterized protein si:ch211-286o17.1", "tax_id": 7955, "disease": "", "pathway": " (dre:100332904)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDK4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IT40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT47-1", "uniprot_id": [ { "id": "A0A0R4IT47_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT47", "type": "external" } ], "mass": 22511.0, "length": 198, "protein_name": "Metalloproteinase inhibitor 4", "gene_name": "timp4.3", "organism": "Zebrafish", "refseq_name": "metalloproteinase inhibitor 4.3 precursor", "refseq_ac": [ { "id": "NP_001313362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313362", "type": "external" } ], "gene_names_uniprotkb": "timp4.3; timp4a; timp4", "gene_names_refseq": "timp4.3; timp4a; timp4", "protein_names_uniprotkb": "Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4", "protein_names_refseq": "TIMP metallopeptidase inhibitor 4a; TIMP2d; metalloproteinase inhibitor 4.3 precursor", "tax_id": 7955, "disease": "ductal carcinoma in situ (Disease Ontology:DOID:0060074); renal hypertension (Disease Ontology:DOID:1073); endometrial cancer (Disease Ontology:DOID:1380); nephroblastoma (Disease Ontology:DOID:2154); endometrial carcinoma (Disease Ontology:DOID:2871); ovarian carcinoma (Disease Ontology:DOID:4001); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); congestive heart failure (Disease Ontology:DOID:6000); abdominal aortic aneurysm (Disease Ontology:DOID:7693); prostate carcinoma in situ (Disease Ontology:DOID:8634)", "pathway": " (dre:100124610)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "17439641;19929220;23594743;25239370;27189481;27516442;30824836;31816958", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC093210.1, EH472853.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH447003.1 and EH479172.1. On May 18, 2016 this sequence version replaced XP_009303999.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3B3", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008191 metalloendopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0051045 negative regulation of membrane protein ectodomain proteolysis;GO:0034097 response to cytokine;GO:0009725 response to hormone", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IT47-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT71-1", "uniprot_id": [ { "id": "A0A0R4IT71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT71", "type": "external" } ], "mass": 119464.0, "length": 1077, "protein_name": "Folliculin-interacting protein 1", "gene_name": "fnip1", "organism": "Zebrafish", "refseq_name": "folliculin-interacting protein 1", "refseq_ac": [ { "id": "NP_001120937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120937", "type": "external" } ], "gene_names_uniprotkb": "fnip1; fc45f03; wu:fc45f03; zgc:175140", "gene_names_refseq": "fc45f03; fnip1; wu:fc45f03; zgc:175140", "protein_names_uniprotkb": "Folliculin-interacting protein 1", "protein_names_refseq": "folliculin-interacting protein 1-like; folliculin-interacting protein 1", "tax_id": 7955, "disease": "immunodeficiency 93 (Disease Ontology:DOID:0061063)", "pathway": " (dre:324863); (R-DRE-9639288)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "23594743;27189481;27519738;30588557", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01046675.1, SRR26395039.43659.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On or before Feb 25, 2016 this sequence version replaced XP_005173972.2, NP_001120937.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and orthologous alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NHL9", "ec_number_list": [], "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0042030 ATPase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005765 lysosomal membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IT71-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT86-1", "uniprot_id": [ { "id": "A0A0R4IT86_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT86", "type": "external" } ], "mass": 81947.0, "length": 755, "protein_name": "Kirre like nephrin family adhesion molecule 3, like precursor; Kirre-like nephrin family adhesion molecule 3, like", "gene_name": "kirrel3l", "organism": "Zebrafish", "refseq_name": "kirre like nephrin family adhesion molecule 3, like precursor", "refseq_ac": [ { "id": "NP_001092814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092814", "type": "external" } ], "gene_names_uniprotkb": "kirrel3l; cb33; kirrel3; sb:cb33; si:dkey-29g23.1; wu:fb74e02", "gene_names_refseq": "cb33; kirrel3l; kirrel3; sb:cb33; si:dkey-29g23.1; wu:fb74e02", "protein_names_uniprotkb": "Kirre like nephrin family adhesion molecule 3, like precursor; Kirre-like nephrin family adhesion molecule 3, like", "protein_names_refseq": "Neph2c; kin of IRRE like 3 like; kirre like nephrin family adhesion molecule 3, like precursor; kirrel2; neph3", "tax_id": 7955, "disease": "", "pathway": " (dre:557315); (R-DRE-373753)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "16750657;17529975;20233749;20802085;20935258;22180726;22286130;23594743;24631215;28252024;30315160", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01015268.1, EF571006.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Sep 8, 2016 this sequence version replaced NP_001092814.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NF10", "ec_number_list": [], "go_molecular_function": "GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0007420 brain development;GO:0007520 myoblast fusion;GO:0072015 podocyte development;GO:0032836 glomerular basement membrane development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IT86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IT98-1", "uniprot_id": [ { "id": "A0A0R4IT98_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IT98", "type": "external" } ], "mass": 40570.0, "length": 356, "protein_name": "Chemerin-like receptor 2; G protein-coupled receptor 1", "gene_name": "cmklr2", "organism": "Zebrafish", "refseq_name": "chemerin-like receptor 2", "refseq_ac": [ { "id": "XP_001343514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001343514", "type": "external" } ], "gene_names_uniprotkb": "cmklr2", "gene_names_refseq": "cmklr2", "protein_names_uniprotkb": "Chemerin-like receptor 2; G protein-coupled receptor 1", "protein_names_refseq": "chemerin-like receptor 2", "tax_id": 7955, "disease": "", "pathway": " (dre:100004124); (R-DRE-391908); (R-DRE-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001343514.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PSR8", "ec_number_list": [], "go_molecular_function": "GO:0004875 complement receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0042923 neuropeptide binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0006935 chemotaxis;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IT98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITC5-1", "uniprot_id": [ { "id": "TRRAP_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITC5", "type": "external" } ], "mass": 435526.0, "length": 3841, "protein_name": "Transformation/transcription domain-associated protein", "gene_name": "trrap", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "trrap; fc54d09; im:7154030; wu:fc54d09", "gene_names_refseq": "", "protein_names_uniprotkb": "Transformation/transcription domain-associated protein", "protein_names_refseq": "", "tax_id": 7955, "disease": "autosomal dominant nonsyndromic deafness (Disease Ontology:DOID:0050564); autosomal dominant nonsyndromic deafness 75 (Disease Ontology:DOID:0112166)", "pathway": " (dre:557263); (R-DRE-201722); (R-DRE-5689880)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "23594743;24240475;26469318;31231791;33871629;34934055", "class_list": "", "function": "Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression (By similarity). May play a role in the formation and maintenance of the auditory system (PubMed:31231791)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000124 SAGA complex", "go_biological_process": "GO:0001964 startle response;GO:0006355 regulation of DNA-templated transcription;GO:0035675 neuromast hair cell development;GO:0060536 cartilage morphogenesis;GO:0042481 regulation of odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4ITC5-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITC7-1", "uniprot_id": [ { "id": "A0A0R4ITC7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITC7", "type": "external" } ], "mass": 93778.0, "length": 835, "protein_name": "Olfactory receptor C family, g4; Olfactory receptor CG4 precursor", "gene_name": "olfcg4", "organism": "Zebrafish", "refseq_name": "olfactory receptor CG4 precursor", "refseq_ac": [ { "id": "NP_001122034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122034", "type": "external" } ], "gene_names_uniprotkb": "olfcg4; si:dkey-245i2.6", "gene_names_refseq": "olfcg4; si:dkey-245i2.6", "protein_names_uniprotkb": "Olfactory receptor C family, g4; Olfactory receptor CG4 precursor", "protein_names_refseq": "A06; Dr9-4; olfactory receptor CG4 precursor; sub 9_3; v2ra6", "tax_id": 7955, "disease": "", "pathway": " (dre:100148438)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.20704625.1, SRR32588722.12483969.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Jul 31, 2008 this sequence version replaced XP_001919322.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NHL1", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4ITC7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITG1-1", "uniprot_id": [ { "id": "A0A0R4ITG1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITG1", "type": "external" } ], "mass": 54840.0, "length": 482, "protein_name": "Mirror-image polydactyly 1; Mirror-image polydactyly gene 1 protein", "gene_name": "mipol1", "organism": "Zebrafish", "refseq_name": "mirror-image polydactyly gene 1 protein", "refseq_ac": [ { "id": "NP_001292396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292396", "type": "external" } ], "gene_names_uniprotkb": "mipol1; hm:zeh0377; zeh0377", "gene_names_refseq": "hm:zeh0377; mipol1; zeh0377", "protein_names_uniprotkb": "Mirror-image polydactyly 1; Mirror-image polydactyly gene 1 protein", "protein_names_refseq": "mirror-image polydactyly gene 1 protein", "tax_id": 7955, "disease": "", "pathway": " (dre:321390)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11116087;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588734.2898606.1, SRR32588723.850570.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Mar 18, 2015 this sequence version replaced XP_002665195.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6A5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ITG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITH7-1", "uniprot_id": [ { "id": "A0A0R4ITH7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITH7", "type": "external" } ], "mass": 68206.0, "length": 609, "protein_name": "poly(ADP-ribose) glycohydrolase", "gene_name": "pargl", "organism": "Zebrafish", "refseq_name": "poly(ADP-ribose) glycohydrolase", "refseq_ac": [ { "id": "XP_001338257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338257", "type": "external" } ], "gene_names_uniprotkb": "pargl", "gene_names_refseq": "pargl", "protein_names_uniprotkb": "poly(ADP-ribose) glycohydrolase; 3.2.1.143", "protein_names_refseq": "poly(ADP-ribose) glycohydrolase", "tax_id": 7955, "disease": "", "pathway": " (dre:797792)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001338257.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q1P0", "ec_number_list": [], "go_molecular_function": "GO:0004649 poly(ADP-ribose) glycohydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009225 nucleotide-sugar metabolic process;GO:0006282 regulation of DNA repair;GO:1990966 ATP generation from poly-ADP-D-ribose", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ITH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITJ3-1", "uniprot_id": [ { "id": "A0A0R4ITJ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITJ3", "type": "external" } ], "mass": 44682.0, "length": 401, "protein_name": "SRY-box transcription factor 8a; Transcription factor SOX-8a isoform X1", "gene_name": "sox8a", "organism": "Zebrafish", "refseq_name": "transcription factor SOX-8a isoform X1", "refseq_ac": [ { "id": "XP_017213911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213911", "type": "external" } ], "gene_names_uniprotkb": "sox8a", "gene_names_refseq": "sox8a", "protein_names_uniprotkb": "SRY-box transcription factor 8a; Transcription factor SOX-8a isoform X1", "protein_names_refseq": "transcription factor SOX-8a isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:102216265)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "23594743;25938946;26469318;32849805;33936955;34122528;34329618", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z1W6", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0014032 neural crest cell development;GO:0002009 morphogenesis of an epithelium", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4ITJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITJ7-1", "uniprot_id": [ { "id": "A0A0R4ITJ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITJ7", "type": "external" } ], "mass": 20183.0, "length": 174, "protein_name": "Si:ch73-311h14.2; Uncharacterized protein LOC556846", "gene_name": "si:ch73-311h14.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC556846", "refseq_ac": [ { "id": "NP_001268902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268902", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-311h14.2; fb76a07; wu:fb76a07; wu:fd43h07", "gene_names_refseq": "fb76a07; si:ch73-311h14.2; wu:fb76a07; wu:fd43h07", "protein_names_uniprotkb": "Si:ch73-311h14.2; Uncharacterized protein LOC556846", "protein_names_refseq": "uncharacterized protein LOC556846", "tax_id": 7955, "disease": "", "pathway": " (dre:556846)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395013.291161.1, SRR26395012.246446.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505382, SAMEA3505386 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P5D2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ITJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITJ9-1", "uniprot_id": [ { "id": "A0A0R4ITJ9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITJ9", "type": "external" } ], "mass": 209746.0, "length": 1892, "protein_name": "protein-tyrosine-phosphatase", "gene_name": "ptprb", "organism": "Zebrafish", "refseq_name": "receptor-type tyrosine-protein phosphatase beta precursor", "refseq_ac": [ { "id": "NP_001303656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303656", "type": "external" } ], "gene_names_uniprotkb": "ptprb; R-PTP-beta", "gene_names_refseq": "R-PTP-beta; ptprb", "protein_names_uniprotkb": "protein-tyrosine-phosphatase; 3.1.3.48", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase beta precursor; zve-ptp", "tax_id": 7955, "disease": "angiosarcoma (Disease Ontology:DOID:0001816); brain glioma (Disease Ontology:DOID:0060108); colorectal carcinoma (Disease Ontology:DOID:0080199); sarcoma (Disease Ontology:DOID:1115); glioblastoma (Disease Ontology:DOID:3068); osteosarcoma (Disease Ontology:DOID:3347); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); thyroid gland carcinoma (Disease Ontology:DOID:3963); breast angiosarcoma (Disease Ontology:DOID:4511); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:100149130); (R-DRE-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "20838449;23251467;23594743;23974070;26469318;28814789;32321550;32801645;34733844;34858981;36910471", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.2514167.1, SRR32588733.1118336.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476740, SAMEA4476747 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jun 25, 2025 this sequence version replaced NP_001303656.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1L1QZQ6;A0A8M1P743", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "1.14.14.18", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.18", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.4.21.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0045296 cadherin binding", "go_cellular_component": "GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001568 blood vessel development;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4ITJ9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITL2-1", "uniprot_id": [ { "id": "A0A0R4ITL2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITL2", "type": "external" } ], "mass": 100671.0, "length": 894, "protein_name": "Uncharacterized protein LOC553526; Zgc:152774", "gene_name": "ZCWCC3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC553526", "refseq_ac": [ { "id": "NP_001307140", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307140", "type": "external" } ], "gene_names_uniprotkb": "ZCWCC3; zgc:152774", "gene_names_refseq": "ZCWCC3; zgc:152774", "protein_names_uniprotkb": "Uncharacterized protein LOC553526; Zgc:152774", "protein_names_refseq": "uncharacterized protein LOC553526", "tax_id": 7955, "disease": "", "pathway": " (dre:553526)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01026643.1, SRR32588715.2807163.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505375, SAMEA3505381 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1, EH435650.1 and EH461649.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments, RNA-seq and orthologous alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8M1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ITL2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITM8-1", "uniprot_id": [ { "id": "A0A0R4ITM8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITM8", "type": "external" } ], "mass": 8145.0, "length": 76, "protein_name": "Si:dkey-203a12.4; Trypsin inhibitor ClTI-1-like; Uncharacterized protein LOC100537905 precursor", "gene_name": "spink2.10", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100537905 precursor", "refseq_ac": [ { "id": "NP_001373480", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373480", "type": "external" } ], "gene_names_uniprotkb": "spink2.10; si:dkey-203a12.4", "gene_names_refseq": "si:dkey-203a12.4; spink2.10", "protein_names_uniprotkb": "Si:dkey-203a12.4; Trypsin inhibitor ClTI-1-like; Uncharacterized protein LOC100537905 precursor", "protein_names_refseq": "uncharacterized protein LOC100537905 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100537905)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BQ450893.1, GFIL01020207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708829, SAMEA708835 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_003199922.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFC4", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ITM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITN2-1", "uniprot_id": [ { "id": "A0A0R4ITN2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITN2", "type": "external" } ], "mass": 51917.0, "length": 465, "protein_name": "Vitamin D-binding protein", "gene_name": "gc", "organism": "Zebrafish", "refseq_name": "vitamin D-binding protein precursor", "refseq_ac": [ { "id": "NP_001002568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002568", "type": "external" } ], "gene_names_uniprotkb": "gc; zgc:110389; zgc:92753", "gene_names_refseq": "gc; zgc:110389; zgc:92753", "protein_names_uniprotkb": "Vitamin D-binding protein; Gc-globulin; Group-specific component", "protein_names_refseq": "dbp; group-specific component (vitamin D binding protein); vitamin D-binding protein precursor", "tax_id": 7955, "disease": "primary progressive multiple sclerosis (Disease Ontology:DOID:0050784); pre-eclampsia (Disease Ontology:DOID:10591); sciatic neuropathy (Disease Ontology:DOID:11446); dengue disease (Disease Ontology:DOID:12205); Graves' disease (Disease Ontology:DOID:12361); neurodegenerative disease (Disease Ontology:DOID:1289); uveitis (Disease Ontology:DOID:13141); hepatic encephalopathy (Disease Ontology:DOID:13413); rheumatic fever (Disease Ontology:DOID:1586); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); endometriosis (Disease Ontology:DOID:289); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); arthritis (Disease Ontology:DOID:848); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dre:436841); (R-DRE-196791)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "19200601;20471496;20653957;22440901;23515471;23594743;36273629;36291156;36396123;36499397;36724876", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC076230.1, GDQQ01036813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001002568.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N0S6", "ec_number_list": [], "go_molecular_function": "GO:0090482 vitamin transmembrane transporter activity;GO:0003779 actin binding;GO:0005499 vitamin D binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0042359 vitamin D metabolic process;GO:0031667 response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4ITN2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITP2-1", "uniprot_id": [ { "id": "A0A0R4ITP2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITP2", "type": "external" } ], "mass": 35180.0, "length": 311, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "atxn3", "organism": "Zebrafish", "refseq_name": "ataxin-3", "refseq_ac": [ { "id": "NP_001307461", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307461", "type": "external" } ], "gene_names_uniprotkb": "atxn3; Mjd; zgc:56323", "gene_names_refseq": "Mjd; atxn3; zgc:56323", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "ataxin-3", "tax_id": 7955, "disease": "late onset Parkinson's disease (Disease Ontology:DOID:0060892); Machado-Joseph disease (Disease Ontology:DOID:1440)", "pathway": " (dre:394079); (R-DRE-5689877); (R-DRE-9615017)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "20040115;23594743;33176149;34315984", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 25, 2025 this sequence version replaced NP_001307461.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7P2", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" } ], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0042461 photoreceptor cell development;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4ITP2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITP4-1", "uniprot_id": [ { "id": "A0A0R4ITP4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITP4", "type": "external" } ], "mass": 76941.0, "length": 680, "protein_name": "MAM domain-containing 2a; MAM domain-containing protein 2a precursor", "gene_name": "mamdc2a", "organism": "Zebrafish", "refseq_name": "MAM domain-containing protein 2a precursor", "refseq_ac": [ { "id": "NP_001123869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123869", "type": "external" } ], "gene_names_uniprotkb": "mamdc2a; si:ch211-117c19.2", "gene_names_refseq": "mamdc2a; si:ch211-117c19.2", "protein_names_uniprotkb": "MAM domain-containing 2a; MAM domain-containing protein 2a precursor", "protein_names_refseq": "MAM domain-containing protein 2a precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:556154)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19478994;23594743;27189481;33757938", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025769.1, GDQH01014870.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jul 23, 2008 this sequence version replaced XP_683982.3., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NIM1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4ITP4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITP7-1", "uniprot_id": [ { "id": "A0A0R4ITP7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITP7", "type": "external" } ], "mass": 151557.0, "length": 1347, "protein_name": "Protein Shroom1; Shroom family member 1", "gene_name": "shroom1", "organism": "Zebrafish", "refseq_name": "protein Shroom1", "refseq_ac": [ { "id": "XP_687790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687790", "type": "external" } ], "gene_names_uniprotkb": "shroom1", "gene_names_refseq": "shroom1", "protein_names_uniprotkb": "Protein Shroom1; Shroom family member 1", "protein_names_refseq": "protein Shroom1", "tax_id": 7955, "disease": "", "pathway": " (dre:559364)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_687790.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TET4", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0030864 cortical actin cytoskeleton;GO:0043296 apical junction complex", "go_biological_process": "GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ITP7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITR4-1", "uniprot_id": [ { "id": "A0A0R4ITR4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITR4", "type": "external" } ], "mass": 60009.0, "length": 523, "protein_name": "GPI mannosyltransferase 2", "gene_name": "pigv", "organism": "Zebrafish", "refseq_name": "palmitoyltransferase ZDHHC18-A", "refseq_ac": [ { "id": "NP_001186989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186989", "type": "external" } ], "gene_names_uniprotkb": "pigv; zdhhc18a", "gene_names_refseq": "pigv; zdhhc18a", "protein_names_uniprotkb": "GPI mannosyltransferase 2; 2.4.1.-", "protein_names_refseq": "GPI mannosyltransferase 2; palmitoyltransferase ZDHHC18-A; zinc finger DHHC domain-containing protein 18-A", "tax_id": 7955, "disease": "hyperphosphatasia with impaired intellectual development syndrome 1 (Disease Ontology:DOID:0070433)", "pathway": " (dre:100148642); (R-DRE-162710)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC135110.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC135110.1., [RefSeq]; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NWM6", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0000030 mannosyltransferase activity;GO:0000009 alpha-1,6-mannosyltransferase activity;GO:0004376 glycolipid mannosyltransferase activity", "go_cellular_component": "GO:0031501 mannosyltransferase complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4ITR4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITS1-1", "uniprot_id": [ { "id": "A0A0R4ITS1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITS1", "type": "external" } ], "mass": 35188.0, "length": 319, "protein_name": "Si:ch211-215k15.4", "gene_name": "si:ch211-215k15.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-215k15.4", "refseq_ac": [ { "id": "XP_021322670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322670", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-215k15.4", "gene_names_refseq": "si:ch211-215k15.4", "protein_names_uniprotkb": "Si:ch211-215k15.4", "protein_names_refseq": "uncharacterized protein si:ch211-215k15.4", "tax_id": 7955, "disease": "", "pathway": " (dre:557984)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PN92", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0042806 fucose binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0001868 regulation of complement activation, lectin pathway;GO:0010185 regulation of cellular defense response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ITS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITS3-1", "uniprot_id": [ { "id": "A0A0R4ITS3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITS3", "type": "external" } ], "mass": 40955.0, "length": 372, "protein_name": "Trophoblast glycoprotein a", "gene_name": "tpbg1b", "organism": "Zebrafish", "refseq_name": "trophoblast glycoprotein a precursor", "refseq_ac": [ { "id": "NP_919373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_919373", "type": "external" } ], "gene_names_uniprotkb": "tpbg1b; YF-296; sb:cb613; tpbga; tpbgl; waif1a; zgc:109764", "gene_names_refseq": "YF-296; sb:cb613; tpbg1b; tpbga; tpbgl; waif1a; zgc:109764", "protein_names_uniprotkb": "Trophoblast glycoprotein a", "protein_names_refseq": "Wnt-activated inhibitory factor 1a; trophoblast glycoprotein a precursor; trophoblast glycoprotein a; trophoblast glycoprotein-like", "tax_id": 7955, "disease": "", "pathway": " (dre:373095)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12045154;12641569;22100263;23594743;27189481;32243887", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: JN653073.1, AB097825.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Dec 16, 2016 this sequence version replaced NP_919373.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PET6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway;GO:0060028 convergent extension involved in axis elongation;GO:2000052 positive regulation of non-canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4ITS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITS5-1", "uniprot_id": [ { "id": "A0A0R4ITS5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITS5", "type": "external" } ], "mass": 67060.0, "length": 598, "protein_name": "dual-specificity kinase", "gene_name": "dyrk2", "organism": "Zebrafish", "refseq_name": "dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1", "refseq_ac": [ { "id": "XP_005164697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164697", "type": "external" } ], "gene_names_uniprotkb": "dyrk2; fc18c09; si:ch211-266a5.8; wu:fa09g03; wu:fc18c09", "gene_names_refseq": "dyrk2; fc18c09; si:ch211-266a5.8; wu:fa09g03; wu:fc18c09", "protein_names_uniprotkb": "dual-specificity kinase; 2.7.12.1", "protein_names_refseq": "dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:557602); (R-DRE-6804756)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "16005068;22898304;23594743;23929741;26469318;27241320;27471727;27658201;28695966", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBR5", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4ITS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITU4-1", "uniprot_id": [ { "id": "A0A0R4ITU4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITU4", "type": "external" } ], "mass": 50892.0, "length": 442, "protein_name": "Uncharacterized protein isoform X1; Zgc:172128", "gene_name": "zgc:172128", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_005168173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168173", "type": "external" } ], "gene_names_uniprotkb": "zgc:172128", "gene_names_refseq": "zgc:172128", "protein_names_uniprotkb": "Uncharacterized protein isoform X1; Zgc:172128", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100002012)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BFI8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ITU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ITX2-1", "uniprot_id": [ { "id": "A0A0R4ITX2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ITX2", "type": "external" } ], "mass": 70248.0, "length": 624, "protein_name": "2.7.11.25; Mitogen-activated protein kinase kinase kinase 22", "gene_name": "map3k22", "organism": "Zebrafish", "refseq_name": "mitogen-activated protein kinase kinase kinase 22", "refseq_ac": [ { "id": "NP_001410597", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410597", "type": "external" } ], "gene_names_uniprotkb": "map3k22; map3k20; zgc:171516", "gene_names_refseq": "map3k20; map3k22; zgc:171516", "protein_names_uniprotkb": "2.7.11.25; Mitogen-activated protein kinase kinase kinase 22", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 20; mitogen-activated protein kinase kinase kinase 22", "tax_id": 7955, "disease": "", "pathway": " (dre:100126011)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "20610484;22627281;23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01012438.1, GFIL01022085.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Aug 8, 2023 this sequence version replaced XP_005162724.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9V2", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4ITX2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IU39-1", "uniprot_id": [ { "id": "A0A0R4IU39_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IU39", "type": "external" } ], "mass": 54911.0, "length": 496, "protein_name": "Cell division cycle 20 homolog; Cell division cycle protein 20 homolog", "gene_name": "cdc20", "organism": "Zebrafish", "refseq_name": "cell division cycle protein 20 homolog", "refseq_ac": [ { "id": "NP_998245", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998245", "type": "external" } ], "gene_names_uniprotkb": "cdc20; wu:fe49f10; zgc:63536; zombie; zom", "gene_names_refseq": "cdc20; wu:fe49f10; zgc:63536; zombie; zom", "protein_names_uniprotkb": "Cell division cycle 20 homolog; Cell division cycle protein 20 homolog", "protein_names_refseq": "cell division cycle protein 20 homolog", "tax_id": 7955, "disease": "", "pathway": " (dre:406353); (R-DRE-141405); (R-DRE-141430); (R-DRE-141444); (R-DRE-174048); (R-DRE-174113); (R-DRE-174154); (R-DRE-174178); (R-DRE-174184); (R-DRE-176407); (R-DRE-176408); (R-DRE-176409); (R-DRE-176417); (R-DRE-179409); (R-DRE-2467813); (R-DRE-2500257); (R-DRE-5663220); (R-DRE-5689880); (R-DRE-983168)", "pathway_count": 19, "publication_count": 11, "publication_id_list": "18629171;19092113;23594743;23968773;24083816;32467236;32822590;35641933;36334626;36846912;9007228", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC054907.1, GDQH01009056.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Apr 18, 2014 this sequence version replaced NP_998245.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AX75", "ec_number_list": [], "go_molecular_function": "GO:0010997 anaphase-promoting complex binding;GO:1990757 ubiquitin ligase activator activity", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:1905786 positive regulation of anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IU39-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IU56-1", "uniprot_id": [ { "id": "A0A0R4IU56_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IU56", "type": "external" } ], "mass": 32159.0, "length": 288, "protein_name": "diphthine methyl ester synthase", "gene_name": "dph5", "organism": "Zebrafish", "refseq_name": "diphthine methyl ester synthase", "refseq_ac": [ { "id": "NP_001007387", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007387", "type": "external" } ], "gene_names_uniprotkb": "dph5; zgc:101823", "gene_names_refseq": "dph5; zgc:101823", "protein_names_uniprotkb": "diphthine methyl ester synthase; 2.1.1.314", "protein_names_refseq": "DPH5 homolog; diphthine methyl ester synthase", "tax_id": 7955, "disease": "neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties (Disease Ontology:DOID:0070479)", "pathway": " (dre:492514); (R-DRE-5358493)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC085447.1, GDQQ01000297.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jun 25, 2025 this sequence version replaced NP_001007387.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N3B4", "ec_number_list": [ { "id": "2.1.1.314", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.314", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0141133 diphthine methyl ester synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0032259 methylation;GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IU56-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IU57-1", "uniprot_id": [ { "id": "A0A0R4IU57_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IU57", "type": "external" } ], "mass": 26529.0, "length": 236, "protein_name": "Calcium-binding protein 2a", "gene_name": "cabp2a", "organism": "Zebrafish", "refseq_name": "calcium-binding protein 2a", "refseq_ac": [ { "id": "NP_001025439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025439", "type": "external" } ], "gene_names_uniprotkb": "cabp2a; zgc:112300", "gene_names_refseq": "cabp2a; zgc:112300", "protein_names_uniprotkb": "Calcium-binding protein 2a", "protein_names_refseq": "calcium-binding protein 2a", "tax_id": 7955, "disease": "autosomal recessive nonsyndromic deafness 93 (Disease Ontology:DOID:0110537)", "pathway": " (dre:572226)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23341937;23594743;25576824;26469318;26695815", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.12623023.1, SRR32588719.67250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On or before Sep 28, 2016 this sequence version replaced XP_005160309.1, NP_001025439.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N7U4", "ec_number_list": [], "go_molecular_function": "GO:0005246 calcium channel regulator activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IU57-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "uniprot_id": [ { "id": "A0A0R4IU63_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IU63", "type": "external" } ], "mass": 130295.0, "length": 1158, "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "organism": "Zebrafish", "refseq_name": "metabotropic glutamate receptor 1b", "refseq_ac": [ { "id": "NP_001289181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289181", "type": "external" } ], "gene_names_uniprotkb": "grm1b; grm1a; grm1; si:ch211-278p9.5", "gene_names_refseq": "grm1a; grm1b; grm1; si:ch211-278p9.5", "protein_names_uniprotkb": "Metabotropic glutamate receptor 5", "protein_names_refseq": "glutamate receptor, metabotropic 1; metabotropic glutamate receptor 1b", "tax_id": 7955, "disease": "autosomal recessive spinocerebellar ataxia 13 (Disease Ontology:DOID:0080062); spinocerebellar ataxia 44 (Disease Ontology:DOID:0080286); temporal lobe epilepsy (Disease Ontology:DOID:3328); uveal melanoma (Disease Ontology:DOID:6039); skin melanoma (Disease Ontology:DOID:8923)", "pathway": " (dre:100150246)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "19500364;22523578;23047810;23594743;27189481;28252024;29551974;32004591;32045791;34566559;35665761", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01012009.1, SRR32588721.3014633.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 25, 2025 this sequence version replaced NP_001289181.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B261", "ec_number_list": [], "go_molecular_function": "GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential;GO:0030296 protein tyrosine kinase activator activity;GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0007206 phospholipase C-activating G protein-coupled glutamate receptor signaling pathway;GO:0051966 regulation of synaptic transmission, glutamatergic;GO:1902533 positive regulation of intracellular signal transduction;GO:0007216 G protein-coupled glutamate receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IU63-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IU78-1", "uniprot_id": [ { "id": "A0A0R4IU78_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IU78", "type": "external" } ], "mass": 65889.0, "length": 594, "protein_name": "Forkhead box O6 a; Forkhead box O6a; Forkhead box protein O6", "gene_name": "foxo6a", "organism": "Zebrafish", "refseq_name": "forkhead box protein O6", "refseq_ac": [ { "id": "XP_690041", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690041", "type": "external" } ], "gene_names_uniprotkb": "foxo6a", "gene_names_refseq": "foxo6a", "protein_names_uniprotkb": "Forkhead box O6 a; Forkhead box O6a; Forkhead box protein O6", "protein_names_refseq": "forkhead box protein O6", "tax_id": 7955, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dre:561541)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;28154937", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690041.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1Q1NMT3", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0001945 lymph vessel development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IU78-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUA4-1", "uniprot_id": [ { "id": "A0A0R4IUA4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUA4", "type": "external" } ], "mass": 41764.0, "length": 359, "protein_name": "Uncharacterized protein LOC103908622; Zgc:173705", "gene_name": "LOC100536900; si:ch211-226o13.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC103908622", "refseq_ac": [ { "id": "NP_001314920", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314920", "type": "external" } ], "gene_names_uniprotkb": "LOC100536900; si:ch211-226o13.2; zgc:173705", "gene_names_refseq": "zgc:173705", "protein_names_uniprotkb": "Uncharacterized protein LOC103908622; Zgc:173705", "protein_names_refseq": "gastrula zinc finger protein XlCGF8.2DB-like; uncharacterized protein LOC103908622", "tax_id": 7955, "disease": "", "pathway": " (dre:100149306); (dre:100536900); (dre:103908622)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.31779077.1, BC171579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMN02418767 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9Q7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IUA4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUB6-1", "uniprot_id": [ { "id": "A0A0R4IUB6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUB6", "type": "external" } ], "mass": 67149.0, "length": 646, "protein_name": "Epsin-1", "gene_name": "epn1a", "organism": "Zebrafish", "refseq_name": "epsin-1", "refseq_ac": [ { "id": "NP_001315045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315045", "type": "external" } ], "gene_names_uniprotkb": "epn1a; epn1; fd51f09; wu:fd51f09; wu:fj90e03; zgc:56381", "gene_names_refseq": "epn1a; epn1; fd51f09; wu:fd51f09; wu:fj90e03; zgc:56381", "protein_names_uniprotkb": "Epsin-1", "protein_names_refseq": "epsin 1; epsin-1", "tax_id": 7955, "disease": "", "pathway": " (dre:406671)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15520368;15621534;23594743;26469318;27189481;30408875", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01022546.1, SRR32588735.938166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_001315045.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8T3", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0030276 clathrin binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IUB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUC9-1", "uniprot_id": [ { "id": "A0A0R4IUC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUC9", "type": "external" } ], "mass": 16189.0, "length": 149, "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "rmi2", "organism": "Zebrafish", "refseq_name": "recQ-mediated genome instability protein 2", "refseq_ac": [ { "id": "XP_691674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691674", "type": "external" } ], "gene_names_uniprotkb": "rmi2", "gene_names_refseq": "rmi2", "protein_names_uniprotkb": "RecQ-mediated genome instability protein 2", "protein_names_refseq": "recQ-mediated genome instability protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:563218); (R-DRE-5685938); (R-DRE-5685942); (R-DRE-5693537); (R-DRE-5693568); (R-DRE-5693579); (R-DRE-5693607); (R-DRE-5693616); (R-DRE-6804756); (R-DRE-69473)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_691674.1. COMPLETENESS: full length., [RefSeq]; Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TDB9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0033045 regulation of sister chromatid segregation;GO:0043007 maintenance of rDNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IUC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUD3-1", "uniprot_id": [ { "id": "A0A0R4IUD3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUD3", "type": "external" } ], "mass": 23209.0, "length": 199, "protein_name": "Mpv17-like protein; Si:dkeyp-72e1.7", "gene_name": "mpv17l", "organism": "Zebrafish", "refseq_name": "mpv17-like protein", "refseq_ac": [ { "id": "XP_691639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691639", "type": "external" } ], "gene_names_uniprotkb": "mpv17l", "gene_names_refseq": "mpv17l", "protein_names_uniprotkb": "Mpv17-like protein; Si:dkeyp-72e1.7", "protein_names_refseq": "mpv17-like protein", "tax_id": 7955, "disease": "", "pathway": " (dre:563178)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TB89", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0016020 membrane", "go_biological_process": "GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IUD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUF0-1", "uniprot_id": [ { "id": "A0A0R4IUF0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUF0", "type": "external" } ], "mass": 176778.0, "length": 1570, "protein_name": "DNA topoisomerase 2", "gene_name": "top2a", "organism": "Zebrafish", "refseq_name": "DNA topoisomerase 2-alpha", "refseq_ac": [ { "id": "NP_001296944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296944", "type": "external" } ], "gene_names_uniprotkb": "top2a; fc08c07; wu:fc08c07", "gene_names_refseq": "fc08c07; top2a; wu:fc08c07", "protein_names_uniprotkb": "DNA topoisomerase 2; 5.6.2.2", "protein_names_refseq": "DNA topoisomerase 2-alpha; topoisomerase (DNA) II alpha; topoisomerase 2", "tax_id": 7955, "disease": "ductal carcinoma in situ (Disease Ontology:DOID:0060074); prostate cancer (Disease Ontology:DOID:10283); urinary bladder cancer (Disease Ontology:DOID:11054); penile benign neoplasm (Disease Ontology:DOID:11624); nephroblastoma (Disease Ontology:DOID:2154); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991)", "pathway": " (dre:323733); (R-DRE-4615885)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "15256591;16109975;16455309;17242348;19139076;23594743;34688465;36417527;36513650;36644807;37024546", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01029878.1, GDQH01005796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1, EB928159.1, EH541591.1 and EH551427.1. On Jun 21, 2015 this sequence version replaced XP_009304762.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7U6", "ec_number_list": [ { "id": "5.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.2", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0007059 chromosome segregation;GO:0048511 rhythmic process;GO:0031100 animal organ regeneration;GO:0006265 DNA topological change", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IUF0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUH5-1", "uniprot_id": [ { "id": "A0A0R4IUH5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUH5", "type": "external" } ], "mass": 25766.0, "length": 235, "protein_name": "Synaptogyrin", "gene_name": "syngr2b", "organism": "Zebrafish", "refseq_name": "synaptogyrin-2b", "refseq_ac": [ { "id": "NP_001076327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076327", "type": "external" } ], "gene_names_uniprotkb": "syngr2b; fj62c03; wu:fj62c03; zgc:162081", "gene_names_refseq": "fj62c03; syngr2b; wu:fj62c03; zgc:162081", "protein_names_uniprotkb": "Synaptogyrin", "protein_names_refseq": "synaptogyrin-2b", "tax_id": 7955, "disease": "", "pathway": " (dre:568509)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH490282.1, BC133858.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505383 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH490282.1, EH547152.1, EH516632.1 and EH607122.1. On Feb 1, 2014 this sequence version replaced XP_696934.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NC39", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031594 neuromuscular junction;GO:0030672 synaptic vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IUH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUJ2-1", "uniprot_id": [ { "id": "A0A0R4IUJ2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUJ2", "type": "external" } ], "mass": 37998.0, "length": 333, "protein_name": "Phosphoinositide-3-kinase, regulatory subunit 3A (gamma)", "gene_name": "pik3r3a", "organism": "Zebrafish", "refseq_name": "phosphoinositide-3-kinase, regulatory subunit 3a (gamma)", "refseq_ac": [ { "id": "NP_001278258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278258", "type": "external" } ], "gene_names_uniprotkb": "pik3r3a; wu:fb16a12; wu:fk56b03; zgc:73230", "gene_names_refseq": "pik3r3a; wu:fb16a12; wu:fk56b03; zgc:73230", "protein_names_uniprotkb": "Phosphoinositide-3-kinase, regulatory subunit 3A (gamma)", "protein_names_refseq": "phosphoinositide-3-kinase, regulatory subunit 3a (gamma)", "tax_id": 7955, "disease": "colon adenocarcinoma (Disease Ontology:DOID:234); high grade glioma (Disease Ontology:DOID:3070); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:406311); (R-DRE-114604); (R-DRE-1257604); (R-DRE-1266695); (R-DRE-1433557); (R-DRE-1660499); (R-DRE-389357); (R-DRE-416476); (R-DRE-6811558); (R-DRE-8853659); (R-DRE-9009391); (R-DRE-9013149); (R-DRE-9013404); (R-DRE-912631)", "pathway_count": 14, "publication_count": 5, "publication_id_list": "23594743;27046191;29258003;30219513;32738032", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588732.3308344.1, SRR32588718.43028382.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH456435.1 and JBMGRA010000002.1. On Apr 4, 2014 this sequence version replaced XP_005163713.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P174", "ec_number_list": [], "go_molecular_function": "GO:0046935 1-phosphatidylinositol-3-kinase regulator activity", "go_cellular_component": "GO:0005943 phosphatidylinositol 3-kinase complex, class IA", "go_biological_process": "GO:0008286 insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IUJ2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUJ5-1", "uniprot_id": [ { "id": "A0A0R4IUJ5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUJ5", "type": "external" } ], "mass": 37065.0, "length": 344, "protein_name": "N-acetyl-D-glucosamine kinase", "gene_name": "nagk", "organism": "Zebrafish", "refseq_name": "N-acetyl-D-glucosamine kinase isoform X1", "refseq_ac": [ { "id": "XP_005166603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166603", "type": "external" } ], "gene_names_uniprotkb": "nagk; zgc:171682", "gene_names_refseq": "nagk; zgc:171682", "protein_names_uniprotkb": "N-acetyl-D-glucosamine kinase; 2.7.1.59; GlcNAc kinase", "protein_names_refseq": "N-acetyl-D-glucosamine kinase isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100126013); (R-DRE-446210)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BE29", "ec_number_list": [ { "id": "2.7.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.59", "type": "external" } ], "go_molecular_function": "GO:0045127 N-acetylglucosamine kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IUJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUL0-1", "uniprot_id": [ { "id": "A0A0R4IUL0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUL0", "type": "external" } ], "mass": 133876.0, "length": 1201, "protein_name": "peptidylprolyl isomerase", "gene_name": "fkbp15b", "organism": "Zebrafish", "refseq_name": "FK506-binding protein 15 isoform X1", "refseq_ac": [ { "id": "XP_009302595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302595", "type": "external" } ], "gene_names_uniprotkb": "fkbp15b", "gene_names_refseq": "fkbp15b", "protein_names_uniprotkb": "peptidylprolyl isomerase; 5.2.1.8", "protein_names_refseq": "FK506-binding protein 15 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:571805)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BC60", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0030426 growth cone", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IUL0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUL8-1", "uniprot_id": [ { "id": "A0A0R4IUL8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUL8", "type": "external" } ], "mass": 96704.0, "length": 861, "protein_name": "NF-kappa-B-repressing factor; NFKB-repressing factor", "gene_name": "nkrf", "organism": "Zebrafish", "refseq_name": "NF-kappa-B-repressing factor", "refseq_ac": [ { "id": "NP_001004499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004499", "type": "external" } ], "gene_names_uniprotkb": "nkrf; fb75e05; nrf; si:bz46j2.5; wu:fb75e05", "gene_names_refseq": "fb75e05; nkrf; nrf; si:bz46j2.5; wu:fb75e05", "protein_names_uniprotkb": "NF-kappa-B-repressing factor; NFKB-repressing factor", "protein_names_refseq": "NF-kappa B-repressing factor; NF-kappa-B-repressing factor; transcription factor", "tax_id": 7955, "disease": "", "pathway": " (dre:797627)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;28385952", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01028293.1, GDQQ01010543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1, EH508388.1, EH444629.1 and EH485701.1. On Nov 25, 2014 this sequence version replaced NP_001004499.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N253", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IUL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "uniprot_id": [ { "id": "A0A0R4IUN8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUN8", "type": "external" } ], "mass": 8343.0, "length": 76, "protein_name": "Si:dkey-203a12.7; Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "organism": "Zebrafish", "refseq_name": "trypsin inhibitor ClTI-1-like precursor", "refseq_ac": [ { "id": "NP_001373550", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373550", "type": "external" } ], "gene_names_uniprotkb": "spink2.9; si:dkey-203a12.7", "gene_names_refseq": "si:dkey-203a12.7; spink2.9", "protein_names_uniprotkb": "Si:dkey-203a12.7; Trypsin inhibitor ClTI-1-like precursor", "protein_names_refseq": "trypsin inhibitor ClTI-1-like precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100538025)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH564992.1, GFIL01020173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_003199925.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RNT3", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IUN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUS2-1", "uniprot_id": [ { "id": "A0A0R4IUS2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUS2", "type": "external" } ], "mass": 119181.0, "length": 1081, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "bmp2k", "organism": "Zebrafish", "refseq_name": "BMP-2-inducible protein kinase isoform 1", "refseq_ac": [ { "id": "NP_001180469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180469", "type": "external" } ], "gene_names_uniprotkb": "bmp2k; zgc:101641", "gene_names_refseq": "bmp2k; zgc:101641", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "BMP-2-inducible protein kinase isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:494101)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15520368;23594743;25420467;28252024;34480404", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01002416.1, SRR32588733.1763591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NX70", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0035612 AP-2 adaptor complex binding;GO:0019208 phosphatase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045747 positive regulation of Notch signaling pathway;GO:2000369 regulation of clathrin-dependent endocytosis;GO:0030500 regulation of bone mineralization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IUS2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUS4-1", "uniprot_id": [ { "id": "A0A0R4IUS4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUS4", "type": "external" } ], "mass": 289775.0, "length": 2702, "protein_name": "Filamin C, gamma a (actin-binding protein 280); Filamin-C isoform X1", "gene_name": "flnca", "organism": "Zebrafish", "refseq_name": "filamin-C isoform X3", "refseq_ac": [ { "id": "XP_002666982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002666982", "type": "external" } ], "gene_names_uniprotkb": "flnca", "gene_names_refseq": "flnca", "protein_names_uniprotkb": "Filamin C, gamma a (actin-binding protein 280); Filamin-C isoform X1", "protein_names_refseq": "filamin-C isoform X3", "tax_id": 7955, "disease": "myofibrillar myopathy 5 (Disease Ontology:DOID:0080096); hypertrophic cardiomyopathy 26 (Disease Ontology:DOID:0110327); distal myopathy 4 (Disease Ontology:DOID:0111190)", "pathway": " (dre:100048921)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RMV6", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005856 cytoskeleton", "go_biological_process": "GO:0007399 nervous system development;GO:0007626 locomotory behavior;GO:0046716 muscle cell cellular homeostasis;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IUS4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUS5-1", "uniprot_id": [ { "id": "A0A0R4IUS5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUS5", "type": "external" } ], "mass": 20459.0, "length": 184, "protein_name": "2.3.2.27; RING finger protein 4", "gene_name": "rnf4", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase RNF4", "refseq_ac": [ { "id": "NP_001373177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373177", "type": "external" } ], "gene_names_uniprotkb": "rnf4; im:7142942; im:7144630; si:ch211-159i8.3", "gene_names_refseq": "im:7142942; im:7144630; rnf4; si:ch211-159i8.3", "protein_names_uniprotkb": "2.3.2.27; RING finger protein 4", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF4", "tax_id": 7955, "disease": "Angelman syndrome (Disease Ontology:DOID:1932)", "pathway": " (dre:557319); (R-DRE-983168)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "23594743;26469318;27189481;29634367;30755680;34135935", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CN019778.1, EH578879.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX004830.7. On or before Aug 15, 2020 this sequence version replaced XP_683428.1, XP_021336817.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PZK4", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "6.3.2.19", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.19", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0140082 SUMO-ubiquitin ligase activity", "go_cellular_component": "", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IUS5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUU4-1", "uniprot_id": [ { "id": "A0A0R4IUU4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUU4", "type": "external" } ], "mass": 20952.0, "length": 185, "protein_name": "NEDD8-conjugating enzyme UBC12", "gene_name": "si:ch1073-205c8.4", "organism": "Zebrafish", "refseq_name": "NEDD8-conjugating enzyme Ubc12", "refseq_ac": [ { "id": "XP_001920670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920670", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-205c8.4; si:ch1073-205c8.3", "gene_names_refseq": "si:ch1073-205c8.3", "protein_names_uniprotkb": "NEDD8-conjugating enzyme UBC12; 2.3.2.34; NEDD8 carrier protein; NEDD8-conjugating enzyme Ubc12; Ubiquitin-conjugating enzyme E2 M", "protein_names_refseq": "NEDD8-conjugating enzyme Ubc12", "tax_id": 7955, "disease": "", "pathway": " (dre:564377); (R-DRE-2173789); (R-DRE-8951664); (R-DRE-983168)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_001920670.2. COMPLETENESS: full length., [RefSeq]; Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QUV9", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" }, { "id": "6.3.2.19", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.19", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "6.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64", "type": "external" } ], "go_molecular_function": "GO:0061654 NEDD8 conjugating enzyme activity;GO:0005524 ATP binding;GO:0019788 NEDD8 transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IUU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IUU9-1", "uniprot_id": [ { "id": "A0A0R4IUU9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IUU9", "type": "external" } ], "mass": 57096.0, "length": 494, "protein_name": "Si:ch73-221f6.3; Zinc finger protein 25-like", "gene_name": "si:ch73-221f6.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_017212654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212654", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-221f6.3; LOC108190743", "gene_names_refseq": "LOC108190743", "protein_names_uniprotkb": "Si:ch73-221f6.3; Zinc finger protein 25-like", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:108190743)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YZL9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IUU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IV01-1", "uniprot_id": [ { "id": "A0A0R4IV01_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IV01", "type": "external" } ], "mass": 101731.0, "length": 925, "protein_name": "2.7.11.1; Ribosomal protein S6 kinase delta-1; Ribosomal protein S6 kinase polypeptide 1", "gene_name": "rps6kc1", "organism": "Zebrafish", "refseq_name": "ribosomal protein S6 kinase delta-1", "refseq_ac": [ { "id": "NP_001352480", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352480", "type": "external" } ], "gene_names_uniprotkb": "rps6kc1; im:7140066; si:ch1073-412h12.1; si:zfos-692b10.1", "gene_names_refseq": "im:7140066; rps6kc1; si:ch1073-412h12.1; si:zfos-692b10.1", "protein_names_uniprotkb": "2.7.11.1; Ribosomal protein S6 kinase delta-1; Ribosomal protein S6 kinase polypeptide 1", "protein_names_refseq": "novel PX domain containing protein; ribosomal protein S6 kinase c, polypeptide 1; ribosomal protein S6 kinase delta-1", "tax_id": 7955, "disease": "", "pathway": " (dre:564322)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01035345.1, GDQH01007380.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jun 25, 2025 this sequence version replaced NP_001352480.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AT05", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005769 early endosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IV01-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IV20-1", "uniprot_id": [ { "id": "A0A0R4IV20_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IV20", "type": "external" } ], "mass": 93027.0, "length": 844, "protein_name": "Olfactory receptor C family, s1; Olfactory receptor CS1", "gene_name": "olfcs1", "organism": "Zebrafish", "refseq_name": "olfactory receptor CS1", "refseq_ac": [ { "id": "NP_001038510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038510", "type": "external" } ], "gene_names_uniprotkb": "olfcs1; si:dkey-188k17.1", "gene_names_refseq": "olfcs1; si:dkey-188k17.1", "protein_names_uniprotkb": "Olfactory receptor C family, s1; Olfactory receptor CS1", "protein_names_refseq": "olfactory receptor CS1; sub 11_2", "tax_id": 7955, "disease": "", "pathway": " (dre:564219)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.25168781.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505380, SAMEA3505390 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Sep 1, 2006 this sequence version replaced XP_692661.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9U6", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IV20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IV80-1", "uniprot_id": [ { "id": "A0A0R4IV80_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IV80", "type": "external" } ], "mass": 7904.0, "length": 69, "protein_name": "NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial", "gene_name": "ndufc1", "organism": "Zebrafish", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial", "refseq_ac": [ { "id": "NP_001268977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268977", "type": "external" } ], "gene_names_uniprotkb": "ndufc1; si:ch211-235e9.6", "gene_names_refseq": "ndufc1; si:ch211-235e9.6", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; Complex I-KFYI; NADH-ubiquinone oxidoreductase KFYI subunit", "protein_names_refseq": "LOC100000992oa; NADH dehydrogenase (ubiquinone) 1 subunit C1, mitochondria-like; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; TCONS_00023933", "tax_id": 7955, "disease": "", "pathway": " (dre:100000992); (R-DRE-611105); (R-DRE-6799198)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;28455512", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CT636491.2, GFIL01014719.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476791 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH543676.1 and JBMGRA010000014.1., [RefSeq]; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P062", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IV80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVA0-1", "uniprot_id": [ { "id": "A0A0R4IVA0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVA0", "type": "external" } ], "mass": 11975.0, "length": 103, "protein_name": "S100 calcium-binding protein W", "gene_name": "s100w", "organism": "Zebrafish", "refseq_name": "S100 calcium binding protein W", "refseq_ac": [ { "id": "NP_001313380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313380", "type": "external" } ], "gene_names_uniprotkb": "s100w", "gene_names_refseq": "s100w", "protein_names_uniprotkb": "S100 calcium-binding protein W", "protein_names_refseq": "S100 calcium binding protein W", "tax_id": 7955, "disease": "", "pathway": " (dre:569958)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18275604;23594743;31546038", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01016002.1, GFIL01024332.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1 and EH465822.1. On May 18, 2016 this sequence version replaced XP_698471.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7Z0", "ec_number_list": [], "go_molecular_function": "GO:0046914 transition metal ion binding;GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IVA0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVA1-1", "uniprot_id": [ { "id": "A0A0R4IVA1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVA1", "type": "external" } ], "mass": 22177.0, "length": 212, "protein_name": "von Willebrand factor D and EGF domain-containing protein precursor; von Willebrand factor D and EGF domains", "gene_name": "seraf", "organism": "Zebrafish", "refseq_name": "von Willebrand factor D and EGF domain-containing protein precursor", "refseq_ac": [ { "id": "NP_001070239", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070239", "type": "external" } ], "gene_names_uniprotkb": "seraf; vwde; zgc:153112", "gene_names_refseq": "seraf; vwde; zgc:153112", "protein_names_uniprotkb": "von Willebrand factor D and EGF domain-containing protein precursor; von Willebrand factor D and EGF domains", "protein_names_refseq": "von Willebrand factor D and EGF domain-containing protein precursor; von Willebrand factor D and EGF domains", "tax_id": 7955, "disease": "", "pathway": " (dre:767804)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26494297;27189481;30924555", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124250.1, EH595620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, EH607559.1, EB799546.1 and EH595620.1. On Nov 5, 2015 this sequence version replaced NP_001070239.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NBC2", "ec_number_list": [], "go_molecular_function": "GO:0038100 nodal binding;GO:0070697 activin receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0021782 glial cell development;GO:0007507 heart development;GO:0060041 retina development in camera-type eye;GO:0001568 blood vessel development;GO:0009952 anterior/posterior pattern specification", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IVA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVA4-1", "uniprot_id": [ { "id": "CC14A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVA4", "type": "external" } ], "mass": 68117.0, "length": 611, "protein_name": "Dual specificity protein phosphatase CDC14AB", "gene_name": "cdc14ab", "organism": "Zebrafish", "refseq_name": "dual specificity protein phosphatase CDC14AB isoform X3", "refseq_ac": [ { "id": "XP_005161772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161772", "type": "external" } ], "gene_names_uniprotkb": "cdc14ab; si:dkey-168j9.1", "gene_names_refseq": "cdc14ab; si:dkey-168j9.1", "protein_names_uniprotkb": "Dual specificity protein phosphatase CDC14AB; 3.1.3.16; 3.1.3.48; CDC14 cell division cycle 14 homolog AB", "protein_names_refseq": "dual specificity protein phosphatase CDC14AB isoform X3", "tax_id": 7955, "disease": "autosomal recessive nonsyndromic deafness 32 (Disease Ontology:DOID:0110491)", "pathway": " (dre:565969); (R-DRE-176407); (R-DRE-5687128)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "21177342;23594743;26469318;27259055;29293958", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0060091 kinocilium", "go_biological_process": "GO:0051301 cell division;GO:0060271 cilium assembly;GO:0007605 sensory perception of sound;GO:0000226 microtubule cytoskeleton organization;GO:0007096 regulation of exit from mitosis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IVA4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVA6-1", "uniprot_id": [ { "id": "A0A0R4IVA6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVA6", "type": "external" } ], "mass": 141928.0, "length": 1245, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "plcb3", "organism": "Zebrafish", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1", "refseq_ac": [ { "id": "XP_005166590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166590", "type": "external" } ], "gene_names_uniprotkb": "plcb3; Plcbeta3; she; si:ch211-188c22.1; si:zc188c22.1; wu:fl04b08", "gene_names_refseq": "Plcbeta3; plcb3; she; si:ch211-188c22.1; si:zc188c22.1; wu:fl04b08", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1", "tax_id": 7955, "disease": "spondylometaphyseal dysplasia with corneal dystrophy (Disease Ontology:DOID:0112303)", "pathway": " (dre:100001532); (R-DRE-112043); (R-DRE-1855204); (R-DRE-416476)", "pathway_count": 4, "publication_count": 12, "publication_id_list": "12588850;17239364;23594743;26469318;28252024;30561090;32296464;32784920;40044042;9007226;9007245;9007254", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Key transducer of G protein-coupled receptor signaling: activated by G(q)/G(11) G alpha proteins downstream of G protein-coupled receptors activation. In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDZ4", "ec_number_list": [ { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" } ], "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005516 calmodulin binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0090281 negative regulation of calcium ion import;GO:0007186 G protein-coupled receptor signaling pathway;GO:0016042 lipid catabolic process;GO:0043116 negative regulation of vascular permeability;GO:0051209 release of sequestered calcium ion into cytosol", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0R4IVA6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVC8-1", "uniprot_id": [ { "id": "A0A0R4IVC8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVC8", "type": "external" } ], "mass": 15516.0, "length": 138, "protein_name": "Cytochrome c oxidase subunit 5A, mitochondrial", "gene_name": "cox5ab", "organism": "Zebrafish", "refseq_name": "cytochrome c oxidase subunit 5Ab", "refseq_ac": [ { "id": "NP_001292506", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292506", "type": "external" } ], "gene_names_uniprotkb": "cox5ab; Cox5a2; cb01f09; cox5a; mg:cb01f09", "gene_names_refseq": "Cox5a2; cb01f09; cox5ab; cox5a; mg:cb01f09", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 5A, mitochondrial; Cytochrome c oxidase polypeptide Va", "protein_names_refseq": "cytochrome c oxidase subunit 5Ab; cytochrome c oxidase subunit Vab; cytochrome c oxidase subunit Va", "tax_id": 7955, "disease": "mitochondrial complex IV deficiency nuclear type 20 (Disease Ontology:DOID:0070505)", "pathway": " (dre:326962)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16109975;17761683;20233836;22465854;23594743;27924917;30082823;30428046;32806454;32947675;33482547", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH546885.1, EH577566.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476756 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1, EH546885.1, EH437300.1 and EH483108.1. On Mar 19, 2015 this sequence version replaced XP_700576.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Analysis of developmental pathology due to cytochrome c oxidase deficiency, [RefSeq, PubMed]; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7E4", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004129 cytochrome-c oxidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0021522 spinal cord motor neuron differentiation;GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0048568 embryonic organ development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IVC8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVE2-1", "uniprot_id": [ { "id": "A0A0R4IVE2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVE2", "type": "external" } ], "mass": 93705.0, "length": 865, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "usp10", "organism": "Zebrafish", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 10 isoform X1", "refseq_ac": [ { "id": "XP_685621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685621", "type": "external" } ], "gene_names_uniprotkb": "usp10", "gene_names_refseq": "usp10", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 10 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:564632); (R-DRE-5656169); (R-DRE-5689880)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_685621.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVN4", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0010506 regulation of autophagy;GO:0016579 protein deubiquitination;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IVE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVF2-1", "uniprot_id": [ { "id": "A0A0R4IVF2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVF2", "type": "external" } ], "mass": 27034.0, "length": 239, "protein_name": "Rho GTPase-activating protein gacN; Si:ch211-1a19.3", "gene_name": "si:ch211-1a19.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-1a19.3", "refseq_ac": [ { "id": "XP_685328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685328", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-1a19.3", "gene_names_refseq": "si:ch211-1a19.3", "protein_names_uniprotkb": "Rho GTPase-activating protein gacN; Si:ch211-1a19.3", "protein_names_refseq": "uncharacterized protein si:ch211-1a19.3", "tax_id": 7955, "disease": "", "pathway": " (dre:557223)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_685328.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UQQ4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IVF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVH6-1", "uniprot_id": [ { "id": "A0A0R4IVH6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVH6", "type": "external" } ], "mass": 73775.0, "length": 646, "protein_name": "2.4.2.30; Protein mono-ADP-ribosyltransferase TIPARP; TCDD-inducible poly(ADP-ribose) polymerase", "gene_name": "tiparp", "organism": "Zebrafish", "refseq_name": "protein mono-ADP-ribosyltransferase TIPARP", "refseq_ac": [ { "id": "NP_001038484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038484", "type": "external" } ], "gene_names_uniprotkb": "tiparp; fc03g05; sb:cb841; si:dkey-33k14.4; wu:fc03g05; zgc:153056", "gene_names_refseq": "fc03g05; sb:cb841; si:dkey-33k14.4; tiparp; wu:fc03g05; zgc:153056", "protein_names_uniprotkb": "2.4.2.30; Protein mono-ADP-ribosyltransferase TIPARP; TCDD-inducible poly(ADP-ribose) polymerase", "protein_names_refseq": "protein mono-ADP-ribosyltransferase TIPARP", "tax_id": 7955, "disease": "", "pathway": " (dre:563506)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "19874812;23594743;25556858;26469318;27189481;35145080", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH433035.1, EE316647.1, EE311950.1, CA472479.1, EB973772.1, EB882039.1, EH459039.1 and AI601719.1. On or before May 7, 2009 this sequence version replaced NP_001038901.1, XP_691960.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9V5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0071466 cellular response to xenobiotic stimulus;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IVH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVI8-1", "uniprot_id": [ { "id": "A0A0R4IVI8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVI8", "type": "external" } ], "mass": 41240.0, "length": 377, "protein_name": "Even-skipped homeobox 1; Homeobox even-skipped homolog protein 1", "gene_name": "evx1", "organism": "Zebrafish", "refseq_name": "homeobox even-skipped homolog protein 1", "refseq_ac": [ { "id": "NP_571324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571324", "type": "external" } ], "gene_names_uniprotkb": "evx1; cb416; evx-1", "gene_names_refseq": "cb416; evx-1; evx1", "protein_names_uniprotkb": "Even-skipped homeobox 1; Homeobox even-skipped homolog protein 1", "protein_names_refseq": "homeobox even-skipped homolog protein 1", "tax_id": 7955, "disease": "", "pathway": " (dre:30499)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10668983;12622731;12880634;14519685;14579383;23594743;32850778;33077489;33334861;35675784;38017520", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01014407.1, GDQH01029718.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476732, SAMEA4476743 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1, EH589447.1, EH606917.1 and AA495010.1. On or before Jun 7, 2016 this sequence version replaced XP_005159566.1, NP_571324.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PBM6", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0072498 embryonic skeletal joint development;GO:0021521 ventral spinal cord interneuron specification;GO:0033334 fin morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IVI8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVK2-1", "uniprot_id": [ { "id": "A0A0R4IVK2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVK2", "type": "external" } ], "mass": 58576.0, "length": 523, "protein_name": "Frizzled-4", "gene_name": "fzd4", "organism": "Zebrafish", "refseq_name": "frizzled-4 precursor", "refseq_ac": [ { "id": "NP_001292398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292398", "type": "external" } ], "gene_names_uniprotkb": "fzd4; fz1; zg01", "gene_names_refseq": "fz1; fzd4; zg01", "protein_names_uniprotkb": "Frizzled-4", "protein_names_refseq": "frizzled homolog 1; frizzled homolog 4; frizzled-4 precursor", "tax_id": 7955, "disease": "exudative vitreoretinopathy (Disease Ontology:DOID:0050535); Norrie disease (Disease Ontology:DOID:0060844); exudative vitreoretinopathy 1 (Disease Ontology:DOID:0111412); prostate carcinoma in situ (Disease Ontology:DOID:8634)", "pathway": " (dre:30363)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "21911385;23349976;23594743;23764775;26818140;32134197;32668265;33481775;35501893;38696577;8626800", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1162722.1, SRR26395013.1235945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Mar 18, 2015 this sequence version replaced XP_005173482.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6U6", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001895 retina homeostasis;GO:0061298 retina vasculature development in camera-type eye;GO:0060070 canonical Wnt signaling pathway;GO:0061299 retina vasculature morphogenesis in camera-type eye;GO:0035567 non-canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IVK2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVM1-1", "uniprot_id": [ { "id": "A0A0R4IVM1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVM1", "type": "external" } ], "mass": 51362.0, "length": 479, "protein_name": "LSM14A mRNA processing body assembly factor b isoform X1; LSM14A mRNA-processing body assembly factor b", "gene_name": "lsm14ab", "organism": "Zebrafish", "refseq_name": "LSM14A mRNA processing body assembly factor b isoform X1", "refseq_ac": [ { "id": "XP_005159030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159030", "type": "external" } ], "gene_names_uniprotkb": "lsm14ab; wu:fc55d12; zgc:55754; zgc:77202", "gene_names_refseq": "lsm14ab; wu:fc55d12; zgc:55754; zgc:77202", "protein_names_uniprotkb": "LSM14A mRNA processing body assembly factor b isoform X1; LSM14A mRNA-processing body assembly factor b", "protein_names_refseq": "LSM14A mRNA processing body assembly factor b isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:406800)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;30174136", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B5Y4", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0000932 P-body;GO:1990904 ribonucleoprotein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0033962 P-body assembly;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IVM1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVN1-1", "uniprot_id": [ { "id": "A0A0R4IVN1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVN1", "type": "external" } ], "mass": 19648.0, "length": 172, "protein_name": "Centrin, EF-hand protein, 2; Centrin-1", "gene_name": "cetn2", "organism": "Zebrafish", "refseq_name": "centrin-1", "refseq_ac": [ { "id": "XP_001345066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345066", "type": "external" } ], "gene_names_uniprotkb": "cetn2", "gene_names_refseq": "cetn2", "protein_names_uniprotkb": "Centrin, EF-hand protein, 2; Centrin-1", "protein_names_refseq": "centrin-1", "tax_id": 7955, "disease": "", "pathway": " (dre:100006257); (R-DRE-3108214); (R-DRE-380320); (R-DRE-5696394); (R-DRE-5696395); (R-DRE-9646399)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PVB9", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005814 centriole", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0007099 centriole replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IVN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVP0-1", "uniprot_id": [ { "id": "A0A0R4IVP0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVP0", "type": "external" } ], "mass": 50485.0, "length": 441, "protein_name": "3.4.13.9; Nuclear receptor subfamily 1, group H, member 3; Oxysterols receptor LXR-alpha", "gene_name": "nr1h3", "organism": "Zebrafish", "refseq_name": "oxysterols receptor LXR-alpha", "refseq_ac": [ { "id": "NP_001017545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017545", "type": "external" } ], "gene_names_uniprotkb": "nr1h3; im:7141239; wu:fd59b01; zgc:113339; zgc:158542", "gene_names_refseq": "im:7141239; nr1h3; wu:fd59b01; zgc:113339; zgc:158542", "protein_names_uniprotkb": "3.4.13.9; Nuclear receptor subfamily 1, group H, member 3; Oxysterols receptor LXR-alpha", "protein_names_refseq": "LXRalpha; liver X receptor; lxr; oxysterols receptor LXR-alpha", "tax_id": 7955, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); carotid stenosis (Disease Ontology:DOID:13001); atherosclerosis (Disease Ontology:DOID:1936); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); ovarian hyperstimulation syndrome (Disease Ontology:DOID:5425); myocardial infarction (Disease Ontology:DOID:5844); cerebrovascular disease (Disease Ontology:DOID:6713); abdominal aortic aneurysm (Disease Ontology:DOID:7693); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:548341); (R-DRE-383280); (R-DRE-4090294); (R-DRE-9029569); (R-DRE-9623433)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "17997606;18297735;18395439;19416695;19451134;23594743;34236575;34301599;34831364;34878094;36835354", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC092160.1, SRR32588717.57119976.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Jan 28, 2016 this sequence version replaced XP_009301489.1, NP_001017545.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Results describe transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N4V7", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" }, { "id": "3.4.13.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.9", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity;GO:0102009 proline dipeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:1904729 regulation of intestinal lipid absorption;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006629 lipid metabolic process;GO:0010875 positive regulation of cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IVP0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVQ3-1", "uniprot_id": [ { "id": "A0A0R4IVQ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVQ3", "type": "external" } ], "mass": 40223.0, "length": 367, "protein_name": "Sc:d189; Uncharacterized protein isoform X1", "gene_name": "sc:d189", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "sc:d189", "gene_names_refseq": "", "protein_names_uniprotkb": "Sc:d189; Uncharacterized protein isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100002334)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3W3", "ec_number_list": [], "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050776 regulation of immune response;GO:0043031 negative regulation of macrophage activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IVQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVS5-1", "uniprot_id": [ { "id": "A0A0R4IVS5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVS5", "type": "external" } ], "mass": 130906.0, "length": 1150, "protein_name": "Alpha-mannosidase", "gene_name": "man2a1", "organism": "Zebrafish", "refseq_name": "alpha-mannosidase 2", "refseq_ac": [ { "id": "NP_001103497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103497", "type": "external" } ], "gene_names_uniprotkb": "man2a1; si:ch211-131c14.1", "gene_names_refseq": "man2a1; si:ch211-131c14.1", "protein_names_uniprotkb": "Alpha-mannosidase; 3.2.1.-", "protein_names_refseq": "alpha-mannosidase 2", "tax_id": 7955, "disease": "congenital dyserythropoietic anemia (Disease Ontology:DOID:1338); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dre:560219); (R-DRE-975578)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "20412557;21816947;23594743;24392132;25329564;26048245;27123470;27417116;28546340;30929901;33634099", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025774.1, GDQH01009036.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001103497.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NG99", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004559 alpha-mannosidase activity;GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006491 N-glycan processing;GO:0006013 mannose metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IVS5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVU1-1", "uniprot_id": [ { "id": "A0A0R4IVU1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVU1", "type": "external" } ], "mass": 17512.0, "length": 157, "protein_name": "Transcription factor MafK isoform X1; V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K", "gene_name": "mafk", "organism": "Zebrafish", "refseq_name": "transcription factor MafK isoform X1", "refseq_ac": [ { "id": "XP_005164260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164260", "type": "external" } ], "gene_names_uniprotkb": "mafk", "gene_names_refseq": "mafk", "protein_names_uniprotkb": "Transcription factor MafK isoform X1; V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K", "protein_names_refseq": "transcription factor MafK isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:415133); (R-DRE-9707616); (R-DRE-9708530); (R-DRE-983231)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "15207702;15654768;23594743;24652768;27189481;31193955;36143473", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBH9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IVU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVU6-1", "uniprot_id": [ { "id": "A0A0R4IVU6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVU6", "type": "external" } ], "mass": 32074.0, "length": 283, "protein_name": "Endonuclease domain-containing 1 protein-like; Si:dkey-243k1.3", "gene_name": "si:dkey-243k1.3", "organism": "Zebrafish", "refseq_name": "endonuclease domain-containing 1 protein-like precursor", "refseq_ac": [ { "id": "NP_001373225", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373225", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-243k1.3", "gene_names_refseq": "si:dkey-243k1.3", "protein_names_uniprotkb": "Endonuclease domain-containing 1 protein-like; Si:dkey-243k1.3", "protein_names_refseq": "endonuclease domain-containing 1 protein-like precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100537487); (R-DRE-114608)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01029336.1, GDQQ01035578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Aug 19, 2020 this sequence version replaced XP_003200071.1, XP_021328579.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFE0", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004519 endonuclease activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IVU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVU8-1", "uniprot_id": [ { "id": "A0A0R4IVU8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVU8", "type": "external" } ], "mass": 16945.0, "length": 150, "protein_name": "Golgi-associated plant pathogenesis-related protein 1; Im:7150988", "gene_name": "im:7150988", "organism": "Zebrafish", "refseq_name": "Golgi-associated plant pathogenesis-related protein 1", "refseq_ac": [ { "id": "XP_002667823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667823", "type": "external" } ], "gene_names_uniprotkb": "im:7150988", "gene_names_refseq": "im:7150988", "protein_names_uniprotkb": "Golgi-associated plant pathogenesis-related protein 1; Im:7150988", "protein_names_refseq": "Golgi-associated plant pathogenesis-related protein 1", "tax_id": 7955, "disease": "", "pathway": " (dre:504039)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RIC7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0071466 cellular response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IVU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVV0-1", "uniprot_id": [ { "id": "MTP_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVV0", "type": "external" } ], "mass": 96988.0, "length": 884, "protein_name": "Microsomal triglyceride transfer protein large subunit", "gene_name": "mttp", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mttp; mtp", "gene_names_refseq": "", "protein_names_uniprotkb": "Microsomal triglyceride transfer protein large subunit", "protein_names_refseq": "", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); hypertension (Disease Ontology:DOID:10763); familial hyperlipidemia (Disease Ontology:DOID:1168); familial hypercholesterolemia (Disease Ontology:DOID:13810); abetalipoproteinemia (Disease Ontology:DOID:1386); hyperinsulinism (Disease Ontology:DOID:2018); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:406207); (R-DRE-8964041)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "15614773;17176039;17924655;22581286;23594743", "class_list": "", "function": "Catalyzes the transport of triglyceride between phospholipid surfaces (PubMed:17924655). Catalyzes the transport of cholesteryl ester, and phospholipid between phospholipid surfaces (By similarity). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:17924655, PubMed:22581286). Required for yolk lipid utilization and absorption of dietary lipids in larvae (PubMed:17176039)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4IGB9;Q8AXV7", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005548 phospholipid transporter activity;GO:0008289 lipid binding;GO:1904121 phosphatidylethanolamine transfer activity;GO:0120013 lipid transfer activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process;GO:0042158 lipoprotein biosynthetic process;GO:0042953 lipoprotein transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IVV0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVX3-1", "uniprot_id": [ { "id": "A0A0R4IVX3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVX3", "type": "external" } ], "mass": 53067.0, "length": 483, "protein_name": "Homeobox protein unc-4 homolog", "gene_name": "uncx", "organism": "Zebrafish", "refseq_name": "homeobox protein unc-4 homolog", "refseq_ac": [ { "id": "XP_005164261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164261", "type": "external" } ], "gene_names_uniprotkb": "uncx", "gene_names_refseq": "uncx", "protein_names_uniprotkb": "Homeobox protein unc-4 homolog", "protein_names_refseq": "homeobox protein unc-4 homolog", "tax_id": 7955, "disease": "", "pathway": " (dre:798510)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBD5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IVX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVX5-1", "uniprot_id": [ { "id": "A0A0R4IVX5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVX5", "type": "external" } ], "mass": 32193.0, "length": 292, "protein_name": "Juxtaposed with another zinc finger protein 1", "gene_name": "jazf1a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "jazf1a; si:ch211-204j16.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Juxtaposed with another zinc finger protein 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:561144)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity. Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD. Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue. Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6F5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IVX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVY2-1", "uniprot_id": [ { "id": "A0A0R4IVY2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVY2", "type": "external" } ], "mass": 47233.0, "length": 436, "protein_name": "Insulin-like growth factor 2 mRNA-binding protein 2b; Uncharacterized protein LOC557028", "gene_name": "igf2bp2b", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC557028", "refseq_ac": [ { "id": "NP_001082843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082843", "type": "external" } ], "gene_names_uniprotkb": "igf2bp2b; si:dkey-24b15.4; wu:fb81e12", "gene_names_refseq": "igf2bp2b; si:dkey-24b15.4; wu:fb81e12", "protein_names_uniprotkb": "Insulin-like growth factor 2 mRNA-binding protein 2b; Uncharacterized protein LOC557028", "protein_names_refseq": "uncharacterized protein LOC557028", "tax_id": 7955, "disease": "acquired metabolic disease (Disease Ontology:DOID:0060158); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:557028)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18803835;23594743;26325373", "class_list": "", "function": "##Evidence-Data-START## CDS exon combination :: EU296399.1, EU296400.1 [ECO:0000331] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from BX088533.9. On May 24, 2007 this sequence version replaced XP_683723.2., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z590", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0070934 CRD-mediated mRNA stabilization;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IVY2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVY9-1", "uniprot_id": [ { "id": "A0A0R4IVY9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVY9", "type": "external" } ], "mass": 84952.0, "length": 725, "protein_name": "Centrosomal protein of 83 kDa", "gene_name": "cep83", "organism": "Zebrafish", "refseq_name": "centrosomal protein of 83 kDa", "refseq_ac": [ { "id": "NP_001340860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001340860", "type": "external" } ], "gene_names_uniprotkb": "cep83; ccdc41", "gene_names_refseq": "ccdc41; cep83", "protein_names_uniprotkb": "Centrosomal protein of 83 kDa", "protein_names_refseq": "centrosomal protein of 83 kDa; coiled-coil domain containing 41; coiled-coil domain-containing protein 41", "tax_id": 7955, "disease": "nephronophthisis 18 (Disease Ontology:DOID:0111125)", "pathway": " (dre:100007472)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23530209;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01003243.1, SRR32588714.16810722.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jul 29, 2017 this sequence version replaced XP_009298702.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; CCDC41 is required for the docking of ciliary vesicles, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AYV6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome", "go_biological_process": "GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IVY9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IVZ0-1", "uniprot_id": [ { "id": "A0A0R4IVZ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IVZ0", "type": "external" } ], "mass": 146300.0, "length": 1436, "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "nup153", "organism": "Zebrafish", "refseq_name": "nuclear pore complex protein Nup153", "refseq_ac": [ { "id": "NP_001313313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313313", "type": "external" } ], "gene_names_uniprotkb": "nup153; fd23d09; si:ch211-153f2.5; wu:fd23d09", "gene_names_refseq": "fd23d09; nup153; si:ch211-153f2.5; wu:fd23d09", "protein_names_uniprotkb": "Nuclear pore complex protein Nup153; 153 kDa nucleoporin; Nucleoporin Nup153", "protein_names_refseq": "nuclear pore complex protein Nup153", "tax_id": 7955, "disease": "", "pathway": " (dre:571621); (R-DRE-159227); (R-DRE-159231); (R-DRE-159236); (R-DRE-191859); (R-DRE-3108214); (R-DRE-3232142); (R-DRE-3301854); (R-DRE-3371453); (R-DRE-4551638)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "15520368;23594743;26221075;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01028940.1, SRR26395012.1245896.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On May 17, 2016 this sequence version replaced XP_005159852.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 10, "predicted_n_glycosites": 0, "predicted_o_glycosites": 10, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8X2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0031965 nuclear membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0051028 mRNA transport;GO:0006405 RNA export from nucleus;GO:0006606 protein import into nucleus;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IVZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IW17-1", "uniprot_id": [ { "id": "A0A0R4IW17_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IW17", "type": "external" } ], "mass": 94143.0, "length": 856, "protein_name": "Olfactory receptor C family, s2; Olfactory receptor CS2", "gene_name": "olfcs2", "organism": "Zebrafish", "refseq_name": "olfactory receptor CS2", "refseq_ac": [ { "id": "NP_001094425", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094425", "type": "external" } ], "gene_names_uniprotkb": "olfcs2; si:dkey-119o24.6", "gene_names_refseq": "olfcs2; si:dkey-119o24.6", "protein_names_uniprotkb": "Olfactory receptor C family, s2; Olfactory receptor CS2", "protein_names_refseq": "Dr11-1; G01; olfactory receptor CS2; pheromone receptor; sub 11-1; v2rg1", "tax_id": 7955, "disease": "", "pathway": " (dre:570726)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.18168735.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505378 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Aug 12, 2007 this sequence version replaced XP_699330.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFG9", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IW17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IW21-1", "uniprot_id": [ { "id": "A0A0R4IW21_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IW21", "type": "external" } ], "mass": 22763.0, "length": 193, "protein_name": "Si:ch211-284k5.2; Sperm axonemal maintenance protein CFAP97D1 isoform X1", "gene_name": "si:ch211-284k5.2", "organism": "Zebrafish", "refseq_name": "sperm axonemal maintenance protein CFAP97D1 isoform X1", "refseq_ac": [ { "id": "XP_697280", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697280", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-284k5.2", "gene_names_refseq": "si:ch211-284k5.2", "protein_names_uniprotkb": "Si:ch211-284k5.2; Sperm axonemal maintenance protein CFAP97D1 isoform X1", "protein_names_refseq": "sperm axonemal maintenance protein CFAP97D1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:568832)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_697280.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFL7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IW21-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IW50-1", "uniprot_id": [ { "id": "A0A0R4IW50_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IW50", "type": "external" } ], "mass": 8506.0, "length": 78, "protein_name": "Si:dkey-203a12.2; Uncharacterized protein LOC100537819 precursor", "gene_name": "spink2.7", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100537819 precursor", "refseq_ac": [ { "id": "NP_001373549", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373549", "type": "external" } ], "gene_names_uniprotkb": "spink2.7; si:dkey-203a12.2", "gene_names_refseq": "si:dkey-203a12.2; spink2.7", "protein_names_uniprotkb": "Si:dkey-203a12.2; Uncharacterized protein LOC100537819 precursor", "protein_names_refseq": "uncharacterized protein LOC100537819 precursor", "tax_id": 7955, "disease": "spermatogenic failure 29 (Disease Ontology:DOID:0111930)", "pathway": " (dre:100537819)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18335061;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC154050.1, CF996283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_003199920.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RNS9", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IW50-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IW71-1", "uniprot_id": [ { "id": "A0A0R4IW71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IW71", "type": "external" } ], "mass": 88944.0, "length": 805, "protein_name": "EMILIN-2; Elastin microfibril interfacer 2b", "gene_name": "emilin2b", "organism": "Zebrafish", "refseq_name": "EMILIN-2 isoform X1", "refseq_ac": [ { "id": "XP_009301913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301913", "type": "external" } ], "gene_names_uniprotkb": "emilin2b", "gene_names_refseq": "emilin2b", "protein_names_uniprotkb": "EMILIN-2; Elastin microfibril interfacer 2b", "protein_names_refseq": "EMILIN-2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:571391); (R-DRE-2129379)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B4K0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IW71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IW80-1", "uniprot_id": [ { "id": "A0A0R4IW80_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IW80", "type": "external" } ], "mass": 20713.0, "length": 200, "protein_name": "Lymphocyte antigen 6 family member M6", "gene_name": "ly6m6", "organism": "Zebrafish", "refseq_name": "lymphocyte antigen 6 family member M6 precursor", "refseq_ac": [ { "id": "NP_001373255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373255", "type": "external" } ], "gene_names_uniprotkb": "ly6m6; ly21.6; si:ch211-134a4.5", "gene_names_refseq": "ly21.6; ly6m6; si:ch211-134a4.5", "protein_names_uniprotkb": "Lymphocyte antigen 6 family member M6", "protein_names_refseq": "lymphocyte antigen 6 family member M6 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100333430)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22415300;23594743;26113395", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH445894.1, CO920072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 19, 2020 this sequence version replaced XP_002665292.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RME5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IW80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWA2-1", "uniprot_id": [ { "id": "A0A0R4IWA2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWA2", "type": "external" } ], "mass": 188522.0, "length": 1721, "protein_name": "Si:dkey-30e9.7; von Willebrand factor D and EGF domain-containing protein", "gene_name": "vwde", "organism": "Zebrafish", "refseq_name": "von Willebrand factor D and EGF domain-containing protein isoform X2", "refseq_ac": [ { "id": "XP_001345360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345360", "type": "external" } ], "gene_names_uniprotkb": "vwde; si:dkey-30e9.7", "gene_names_refseq": "vwde", "protein_names_uniprotkb": "Si:dkey-30e9.7; von Willebrand factor D and EGF domain-containing protein", "protein_names_refseq": "von Willebrand factor D and EGF domain-containing protein isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:100006681)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001345360.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PVC7", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IWA2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWE4-1", "uniprot_id": [ { "id": "A0A0R4IWE4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWE4", "type": "external" } ], "mass": 25100.0, "length": 220, "protein_name": "Si:ch211-57n23.1", "gene_name": "si:ch211-57n23.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-57n23.1 isoform X1", "refseq_ac": [ { "id": "XP_001921495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921495", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-57n23.1", "gene_names_refseq": "si:ch211-57n23.1", "protein_names_uniprotkb": "Si:ch211-57n23.1", "protein_names_refseq": "uncharacterized protein si:ch211-57n23.1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100148952)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_001921495.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QKL1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IWE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWF3-1", "uniprot_id": [ { "id": "A0A0R4IWF3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWF3", "type": "external" } ], "mass": 59847.0, "length": 548, "protein_name": "Zinc finger and BTB domain-containing 3; Zinc finger and BTB domain-containing protein 3", "gene_name": "zbtb3", "organism": "Zebrafish", "refseq_name": "zinc finger and BTB domain-containing protein 3", "refseq_ac": [ { "id": "XP_009289486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289486", "type": "external" } ], "gene_names_uniprotkb": "zbtb3", "gene_names_refseq": "zbtb3", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing 3; Zinc finger and BTB domain-containing protein 3", "protein_names_refseq": "zinc finger and BTB domain-containing protein 3", "tax_id": 7955, "disease": "", "pathway": " (dre:100003975)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3APC5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IWF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWF6-1", "uniprot_id": [ { "id": "A0A0R4IWF6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWF6", "type": "external" } ], "mass": 29863.0, "length": 271, "protein_name": "Uncharacterized protein LOC550593 precursor; Zgc:113293", "gene_name": "zgc:113293", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC550593 precursor", "refseq_ac": [ { "id": "NP_001017894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017894", "type": "external" } ], "gene_names_uniprotkb": "zgc:113293", "gene_names_refseq": "zgc:113293", "protein_names_uniprotkb": "Uncharacterized protein LOC550593 precursor; Zgc:113293", "protein_names_refseq": "uncharacterized protein LOC550593 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:550593)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;35886872", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA898400, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH549464.1 and EH577932.1. On Apr 4, 2014 this sequence version replaced NP_001017894.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N5G4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IWF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWG0-1", "uniprot_id": [ { "id": "A0A0R4IWG0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWG0", "type": "external" } ], "mass": 16380.0, "length": 148, "protein_name": "Epigen precursor; Epithelial mitogen homolog (mouse)", "gene_name": "epgn", "organism": "Zebrafish", "refseq_name": "epigen precursor", "refseq_ac": [ { "id": "NP_001373613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373613", "type": "external" } ], "gene_names_uniprotkb": "epgn", "gene_names_refseq": "epgn", "protein_names_uniprotkb": "Epigen precursor; Epithelial mitogen homolog (mouse)", "protein_names_refseq": "epigen precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100005297); (R-DRE-1257604); (R-DRE-177929); (R-DRE-179812); (R-DRE-180292); (R-DRE-180336); (R-DRE-182971); (R-DRE-212718); (R-DRE-5673001); (R-DRE-6811558)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "20105326;23594743;27189481;27846271", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01010347.1, GDQQ01046765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Mar 1, 2023 this sequence version replaced XP_001344391.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PZS8", "ec_number_list": [], "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0045840 positive regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IWG0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWG9-1", "uniprot_id": [ { "id": "GCNA_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWG9", "type": "external" } ], "mass": 65421.0, "length": 586, "protein_name": "Germ cell nuclear acidic protein", "gene_name": "gcna", "organism": "Zebrafish", "refseq_name": "germ cell nuclear acidic protein isoform X1", "refseq_ac": [ { "id": "XP_021336691", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336691", "type": "external" } ], "gene_names_uniprotkb": "gcna; acrc", "gene_names_refseq": "acrc; gcna; zgc:113346", "protein_names_uniprotkb": "Germ cell nuclear acidic protein; Acidic repeat-containing protein; Germ cell nuclear acidic peptidase", "protein_names_refseq": "germ cell nuclear acidic protein isoform X1", "tax_id": 7955, "disease": "X-linked spermatogenic failure 4 (Disease Ontology:DOID:0070595)", "pathway": " (dre:541448)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;31839537", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in DNA-protein cross-links (DPCs) clearance, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0016605 PML body;GO:0005694 chromosome", "go_biological_process": "GO:0051983 regulation of chromosome segregation;GO:0106300 protein-DNA covalent cross-linking repair;GO:0140014 mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IWG9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWH1-1", "uniprot_id": [ { "id": "A0A0R4IWH1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWH1", "type": "external" } ], "mass": 108890.0, "length": 974, "protein_name": "E3 SUMO-protein ligase ZBED1 isoform X1; Si:dkeyp-117b8.4", "gene_name": "zbed4l2", "organism": "Zebrafish", "refseq_name": "E3 SUMO-protein ligase ZBED1 isoform X1", "refseq_ac": [ { "id": "XP_005165631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165631", "type": "external" } ], "gene_names_uniprotkb": "zbed4l2; si:dkeyp-117b8.4", "gene_names_refseq": "zbed4l2", "protein_names_uniprotkb": "E3 SUMO-protein ligase ZBED1 isoform X1; Si:dkeyp-117b8.4", "protein_names_refseq": "E3 SUMO-protein ligase ZBED1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101884515)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BD26", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0046983 protein dimerization activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IWH1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWH7-1", "uniprot_id": [ { "id": "A0A0R4IWH7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWH7", "type": "external" } ], "mass": 301092.0, "length": 2754, "protein_name": "APC regulator of WNT-signaling pathway; Adenomatous polyposis coli protein", "gene_name": "apc", "organism": "Zebrafish", "refseq_name": "adenomatous polyposis coli protein", "refseq_ac": [ { "id": "NP_001137312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137312", "type": "external" } ], "gene_names_uniprotkb": "apc; cb965; im:7150932; im:7152872", "gene_names_refseq": "apc; cb965; im:7150932; im:7152872", "protein_names_uniprotkb": "APC regulator of WNT-signaling pathway; Adenomatous polyposis coli protein", "protein_names_refseq": "adenomatosis polyposis coli; adenomatous polyposis coli protein; adenomatous polyposis coli", "tax_id": 7955, "disease": "familial adenomatous polyposis (Disease Ontology:DOID:0050424); medulloblastoma (Disease Ontology:DOID:0050902); familial adenomatous polyposis 1 (Disease Ontology:DOID:0080409); hereditary desmoid disease (Disease Ontology:DOID:0111349); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovarian cancer (Disease Ontology:DOID:2394); transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial carcinoma (Disease Ontology:DOID:2871); adenocarcinoma (Disease Ontology:DOID:299); acinar cell carcinoma (Disease Ontology:DOID:3025); gallbladder cancer (Disease Ontology:DOID:3121); renal cell carcinoma (Disease Ontology:DOID:4450); cholangiocarcinoma (Disease Ontology:DOID:4947); adenoma (Disease Ontology:DOID:657); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dre:386762); (R-DRE-111465); (R-DRE-195253); (R-DRE-196299); (R-DRE-5689896)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "14534590;15358764;15967793;16439994;16699180;23594743;31624259;32467235;35132438;37407577;37489330", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505374, SAMEA3505377 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; APC control of retinoic acid biosynthesis is critical for zebrafish intestinal development and differentiation, [RefSeq, PubMed]; APC controls the production of RA in the gut by regulating the expression of the retinol dehydrogenase, rdh1l, [RefSeq, PubMed]; Mutations in the APC gene resultt in impaired retinoic acid biosynthesis and upegulation of cyclooxygenase-2., [RefSeq, PubMed]; Zebrafish that are heterozygous for a truncating denomatous polyposis coli mutation spontaneously develop intestinal, hepatic and pancreatic neoplasias [Adenomatous polyposis coli], [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NSU1", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0044877 protein-containing complex binding;GO:0008013 beta-catenin binding;GO:0045295 gamma-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030054 cell junction;GO:0015630 microtubule cytoskeleton;GO:0016342 catenin complex", "go_biological_process": "GO:0001708 cell fate specification;GO:0003170 heart valve development;GO:0061031 endodermal digestive tract morphogenesis;GO:0001889 liver development;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IWH7-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWI1-1", "uniprot_id": [ { "id": "COE1A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWI1", "type": "external" } ], "mass": 64371.0, "length": 591, "protein_name": "Transcription factor COE1-A", "gene_name": "ebf1a; ebf3a", "organism": "Zebrafish", "refseq_name": "transcription factor COE1-A isoform 1", "refseq_ac": [ { "id": "NP_001410899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410899", "type": "external" } ], "gene_names_uniprotkb": "ebf1a; ebf3a; ebf3; sb:eu427; si:ch73-38f1.1; zgc:158829", "gene_names_refseq": "ebf1a; sb:eu427; si:ch73-38f1.1", "protein_names_uniprotkb": "Transcription factor COE1-A; Early B cell factor 1-A", "protein_names_refseq": "early B cell factor 1-A; early B cell factor 1a; transcription factor COE1-A isoform 1; transcription factor COE1-A; transcription factor COE1", "tax_id": 7955, "disease": "hypotonia, ataxia, and delayed development syndrome (Disease Ontology:DOID:0081176); lipodystrophy (Disease Ontology:DOID:811)", "pathway": " (dre:565310); (dre:567751)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "19449054;21061380;23594743;24034702;26095893;26982811;27189481;27615194;30045885;30681411;31908317;34667153;36414621;38017520", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.30964552.1, SRR32588725.35229425.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505389, SAMEA4476738 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 23, 2023 this sequence version replaced XP_009289484.1., [RefSeq]; Transcriptional activator., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IW26;A0A0R4IWS1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0045893 positive regulation of DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0R4IWI1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWI7-1", "uniprot_id": [ { "id": "A0A0R4IWI7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWI7", "type": "external" } ], "mass": 117738.0, "length": 1033, "protein_name": "Kinesin family member 5A, a; Kinesin family member 5Aa", "gene_name": "kif5aa", "organism": "Zebrafish", "refseq_name": "kinesin family member 5Aa", "refseq_ac": [ { "id": "NP_001186705", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186705", "type": "external" } ], "gene_names_uniprotkb": "kif5aa; kif5a; si:ch211-166e11.4; vertigo; vrt; wu:fj61a10", "gene_names_refseq": "kif5aa; kif5a; si:ch211-166e11.4; vertigo; vrt; wu:fj61a10", "protein_names_uniprotkb": "Kinesin family member 5A, a; Kinesin family member 5Aa", "protein_names_refseq": "kinesin family member 5Aa", "tax_id": 7955, "disease": "amyotrophic lateral sclerosis type 25 (Disease Ontology:DOID:0081379); hereditary spastic paraplegia 10 (Disease Ontology:DOID:0110763); prostate cancer (Disease Ontology:DOID:10283); multiple sclerosis (Disease Ontology:DOID:2377); rheumatoid arthritis (Disease Ontology:DOID:7148); asbestos-related lung carcinoma (Disease Ontology:DOID:7596)", "pathway": " (dre:566086); (R-DRE-5625970); (R-DRE-983189)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "23594743;23684767;24179142;25355224;26076409;26957310;27189481;28193224;36459488", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01014007.1, SRR26395015.206512.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC095088.1 and JBMGRA010000009.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Deletion of a kinesin I motor unmasks a mechanism of homeostatic axon-branching control by neurotrophin-3. Publication Status: Online-Only, [RefSeq, PubMed]; Our results shed light on Kinesin complexity and reveal determinants of specific Kif5A functions in mitochondrial transport, adaptor binding, and axonal maintenance., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NWH1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0032839 dendrite cytoplasm;GO:1904115 axon cytoplasm", "go_biological_process": "GO:1990535 neuron projection maintenance;GO:0007411 axon guidance;GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex;GO:0048489 synaptic vesicle transport;GO:0019896 axonal transport of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IWI7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWL6-1", "uniprot_id": [ { "id": "A0A0R4IWL6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWL6", "type": "external" } ], "mass": 123089.0, "length": 1152, "protein_name": "Pumilio homolog 1", "gene_name": "pum1", "organism": "Zebrafish", "refseq_name": "pumilio homolog 1", "refseq_ac": [ { "id": "NP_001264048", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264048", "type": "external" } ], "gene_names_uniprotkb": "pum1; fb96a03; pumilio1; si:ch211-285e16.1; wu:fb96a03; wu:fb96a08; zgc:63671", "gene_names_refseq": "fb96a03; pum1; pumilio1; si:ch211-285e16.1; wu:fb96a03; wu:fb96a08; zgc:63671", "protein_names_uniprotkb": "Pumilio homolog 1", "protein_names_refseq": "pumilio homolog 1 pseudogene; pumilio homolog 1", "tax_id": 7955, "disease": "cerebellar ataxia type 47 (Disease Ontology:DOID:0111743)", "pathway": " (dre:394176)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "23594743;24062337;28381614;30103945;30289101;33148609;35588359", "class_list": "", "function": "##Evidence-Data-START## CDS exon combination :: AB841266.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC055197.1 and AB841266.1. On Nov 20, 2014 this sequence version replaced NP_001264060.1., [RefSeq]; Pum1 phosphorylation in the early period of oocyte maturation is one of the key processes for promoting the disassembly of cyclin B1 RNA granules and translational activation of target mRNA., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NZX5", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "GO:0006417 regulation of translation;GO:0043488 regulation of mRNA stability;GO:0035196 miRNA processing;GO:0019094 pole plasm mRNA localization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IWL6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWN8-1", "uniprot_id": [ { "id": "A0A0R4IWN8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWN8", "type": "external" } ], "mass": 10121.0, "length": 93, "protein_name": "Non-histone chromosomal protein HMG-14A-like; Si:ch73-281n10.2", "gene_name": "hmgn1a", "organism": "Zebrafish", "refseq_name": "Non-histone chromosomal protein HMG-14A-like", "refseq_ac": [ { "id": "NP_001296573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296573", "type": "external" } ], "gene_names_uniprotkb": "hmgn1a; linc-wrb; si:ch73-281n10.2; wu:fa95c02; wu:fb74d02", "gene_names_refseq": "hmgn1a; linc-wrb; si:ch73-281n10.2; wu:fa95c02; wu:fb74d02", "protein_names_uniprotkb": "Non-histone chromosomal protein HMG-14A-like; Si:ch73-281n10.2", "protein_names_refseq": "Non-histone chromosomal protein HMG-14A-like; non-histone chromosomal protein HMG-17", "tax_id": 7955, "disease": "", "pathway": " (dre:561719)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11116087;23594743;24705786;26593130;27189481;37191016", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC142830.1, CO914508.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, EH450941.1, EH523724.1, EH557609.1 and EH463221.1. On Jul 12, 2016 this sequence version replaced XP_005169755.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7Q0", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0031492 nucleosomal DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IWN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWR0-1", "uniprot_id": [ { "id": "A0A0R4IWR0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWR0", "type": "external" } ], "mass": 42989.0, "length": 369, "protein_name": "Fucosyltransferase", "gene_name": "fut9b.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_068079053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079053", "type": "external" } ], "gene_names_uniprotkb": "fut9b.6; zgc:112433", "gene_names_refseq": "fut9b.6; zgc:112433", "protein_names_uniprotkb": "Fucosyltransferase; 2.4.1.-", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:550469)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AUU0", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" } ], "go_molecular_function": "GO:0046920 alpha-(1->3)-fucosyltransferase activity;GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IWR0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWU8-1", "uniprot_id": [ { "id": "A0A0R4IWU8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWU8", "type": "external" } ], "mass": 32636.0, "length": 296, "protein_name": "1.1.1.300; Si:dkey-73n8.3; Uncharacterized protein LOC100150965", "gene_name": "si:dkey-73n8.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100150965", "refseq_ac": [ { "id": "NP_001186991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186991", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-73n8.3", "gene_names_refseq": "si:dkey-73n8.3", "protein_names_uniprotkb": "1.1.1.300; Si:dkey-73n8.3; Uncharacterized protein LOC100150965", "protein_names_refseq": "retinol dehydrogenase 12-like; uncharacterized protein LOC100150965", "tax_id": 7955, "disease": "", "pathway": " (dre:100150965); (R-DRE-2453902)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from DT068986.1 and BC122353.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NXM3", "ec_number_list": [ { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" } ], "go_molecular_function": "GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IWU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IWV6-1", "uniprot_id": [ { "id": "A0A0R4IWV6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IWV6", "type": "external" } ], "mass": 38512.0, "length": 334, "protein_name": "G protein-coupled receptor 184", "gene_name": "gpr184", "organism": "Zebrafish", "refseq_name": "G protein-coupled receptor 184", "refseq_ac": [ { "id": "NP_001296782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296782", "type": "external" } ], "gene_names_uniprotkb": "gpr184; zgc:152692", "gene_names_refseq": "gpr184; zgc:152692", "protein_names_uniprotkb": "G protein-coupled receptor 184", "protein_names_refseq": "G protein-coupled receptor 184", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-373076); (R-DRE-416476)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "21873635;23594743;31064998", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.29552701.1, SRR32588732.33298432.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Jul 24, 2025 this sequence version replaced XP_073779386.1, NP_001070177.1, XP_009289798.1. Sequence Note:., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6S8", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IWV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IX00-1", "uniprot_id": [ { "id": "A0A0R4IX00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IX00", "type": "external" } ], "mass": 62591.0, "length": 573, "protein_name": "Si:ch1073-224n8.1", "gene_name": "si:ch1073-224n8.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch1073-224n8.1", "refseq_ac": [ { "id": "XP_001921563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921563", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-224n8.1", "gene_names_refseq": "si:ch1073-224n8.1", "protein_names_uniprotkb": "Si:ch1073-224n8.1", "protein_names_refseq": "uncharacterized protein si:ch1073-224n8.1", "tax_id": 7955, "disease": "", "pathway": " (dre:327438); (R-DRE-9843940)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QV16", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IX00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IX01-1", "uniprot_id": [ { "id": "A0A0R4IX01_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IX01", "type": "external" } ], "mass": 112789.0, "length": 994, "protein_name": "Beta-klotho; Klotho beta", "gene_name": "klb", "organism": "Zebrafish", "refseq_name": "beta-klotho", "refseq_ac": [ { "id": "XP_009305920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305920", "type": "external" } ], "gene_names_uniprotkb": "klb", "gene_names_refseq": "klb", "protein_names_uniprotkb": "Beta-klotho; Klotho beta", "protein_names_refseq": "beta-klotho", "tax_id": 7955, "disease": "", "pathway": " (dre:796269); (R-DRE-109704); (R-DRE-1257604); (R-DRE-1307965); (R-DRE-5654228); (R-DRE-5654712); (R-DRE-5654719); (R-DRE-5654720); (R-DRE-5654733); (R-DRE-5673001); (R-DRE-6811558)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B5K5", "ec_number_list": [], "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IX01-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IX64-1", "uniprot_id": [ { "id": "A0A0R4IX64_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IX64", "type": "external" } ], "mass": 73492.0, "length": 679, "protein_name": "Si:ch73-132f6.5; Uncharacterized protein lratb.1 isoform X1", "gene_name": "LOC137487234; lratb.1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC137487234; lratb.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Si:ch73-132f6.5; Uncharacterized protein lratb.1 isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "Leber congenital amaurosis 14 (Disease Ontology:DOID:0110188); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (dre:553501); (R-DRE-2453902); (R-DRE-975634)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B744", "ec_number_list": [], "go_molecular_function": "GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum", "go_biological_process": "GO:0042572 retinol metabolic process;GO:0006776 vitamin A metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IX64-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IX71-1", "uniprot_id": [ { "id": "A0A0R4IX71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IX71", "type": "external" } ], "mass": 38754.0, "length": 348, "protein_name": "Si:ch211-209l18.4", "gene_name": "si:ch211-209l18.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-209l18.4", "refseq_ac": [ { "id": "XP_001923591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923591", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-209l18.4", "gene_names_refseq": "si:ch211-209l18.4", "protein_names_uniprotkb": "Si:ch211-209l18.4", "protein_names_refseq": "uncharacterized protein si:ch211-209l18.4", "tax_id": 7955, "disease": "", "pathway": " (dre:100149940)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_001923591.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QHX2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IX71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXA2-1", "uniprot_id": [ { "id": "A0A0R4IXA2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXA2", "type": "external" } ], "mass": 41400.0, "length": 373, "protein_name": "Cellular communication network factor 1, like 2 precursor; Cellular communication network factor 1,-like 2", "gene_name": "ccn1l2", "organism": "Zebrafish", "refseq_name": "cellular communication network factor 1, like 2 precursor", "refseq_ac": [ { "id": "NP_001074456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074456", "type": "external" } ], "gene_names_uniprotkb": "ccn1l2; cyr61-l2; cyr61l2; cyr61; zCyr61-c8; zgc:158158", "gene_names_refseq": "ccn1l2; cyr61-l2; cyr61l2; cyr61; zCyr61-c8; zgc:158158", "protein_names_uniprotkb": "Cellular communication network factor 1, like 2 precursor; Cellular communication network factor 1,-like 2", "protein_names_refseq": "cellular communication network factor 1, like 2 precursor; cysteine-rich, angiogenic inducer, 61 like 2", "tax_id": 7955, "disease": "", "pathway": " (dre:553273)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "15725073;20503371;23594743;24051129;26930480;27130971;27189481;27428308;30348863;31429823;37122014", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.1175148.1, SRR26395013.67090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505379 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On or before Jan 5, 2017 this sequence version replaced XP_017212820.1, NP_001074456.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NBV7", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0030335 positive regulation of cell migration;GO:0045597 positive regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IXA2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXA9-1", "uniprot_id": [ { "id": "A0A0R4IXA9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXA9", "type": "external" } ], "mass": 51374.0, "length": 468, "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "cap2", "organism": "Zebrafish", "refseq_name": "adenylyl cyclase-associated protein 2", "refseq_ac": [ { "id": "NP_957130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957130", "type": "external" } ], "gene_names_uniprotkb": "cap2; zgc:113089; zgc:73317", "gene_names_refseq": "cap2; zgc:113089; zgc:73317", "protein_names_uniprotkb": "Adenylyl cyclase-associated protein", "protein_names_refseq": "CAP, adenylate cyclase-associated protein, 2; adenylyl cyclase-associated protein 2", "tax_id": 7955, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (dre:393809)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23022774;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC091655.1, SRR32588720.972379.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC091655.1 and JBMGRA010000019.1. On or before May 27, 2016 this sequence version replaced XP_005159849.1, NP_957130.1., [RefSeq]; CAP2 plays an important role in enhancing cell motility, which may promote a more invasive behavior in the progression of hepatocellular carcinoma., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z2X3", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0008179 adenylate cyclase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0000902 cell morphogenesis;GO:0019933 cAMP-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IXA9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXC8-1", "uniprot_id": [ { "id": "A0A0R4IXC8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXC8", "type": "external" } ], "mass": 50090.0, "length": 447, "protein_name": "Tubulin beta chain", "gene_name": "tubb6", "organism": "Zebrafish", "refseq_name": "tubulin, beta 6 class V isoform 1", "refseq_ac": [ { "id": "NP_001017762", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017762", "type": "external" } ], "gene_names_uniprotkb": "tubb6; si:ch211-9a18.2; zgc:112515", "gene_names_refseq": "si:ch211-9a18.2; tubb6; zgc:112515", "protein_names_uniprotkb": "Tubulin beta chain", "protein_names_refseq": "tubulin, beta 6 class V isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:550458); (R-DRE-2467813); (R-DRE-2500257)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "23594743;24947308;27189481;33316259", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01040434.1, GDQQ01016458.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476737, SAMEA4476754 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On or before Jun 16, 2016 this sequence version replaced XP_005162994.1, NP_001017762.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N5M5", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0000226 microtubule cytoskeleton organization;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IXC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXF0-1", "uniprot_id": [ { "id": "A0A0R4IXF0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXF0", "type": "external" } ], "mass": 22111.0, "length": 192, "protein_name": "FAS-associated death domain protein", "gene_name": "fadd", "organism": "Zebrafish", "refseq_name": "FAS-associated death domain protein", "refseq_ac": [ { "id": "NP_001373289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373289", "type": "external" } ], "gene_names_uniprotkb": "fadd", "gene_names_refseq": "fadd", "protein_names_uniprotkb": "FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associated death domain protein", "protein_names_refseq": "FAS-associated death domain protein", "tax_id": 7955, "disease": "immunodeficiency 90 (Disease Ontology:DOID:0061060); Alzheimer's disease (Disease Ontology:DOID:10652); leukemia (Disease Ontology:DOID:1240); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (dre:562317); (R-DRE-3371378); (R-DRE-5218900); (R-DRE-5357786); (R-DRE-5357905); (R-DRE-5675482); (R-DRE-69416); (R-DRE-75158)", "pathway_count": 8, "publication_count": 11, "publication_id_list": "16888647;17656375;20573960;22357656;23594743;24627485;27356472;27471679;27834691;31492028;33535128", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC114285.1, EE111276.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 21, 2020 this sequence version replaced XP_001923893.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling., [UniProtKB, UniProtKB]; Establish that pax2 in combination with vax2 directly regulate the fas-associated death domain (fadd) gene, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QLU8", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0089720 caspase binding;GO:0005123 death receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031265 CD95 death-inducing signaling complex", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0045087 innate immune response;GO:0001819 positive regulation of cytokine production;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0097191 extrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IXF0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXF5-1", "uniprot_id": [ { "id": "A0A0R4IXF5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXF5", "type": "external" } ], "mass": 27520.0, "length": 258, "protein_name": "Uncharacterized protein LOC447817; Zgc:92161", "gene_name": "zgc:92161", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC447817", "refseq_ac": [ { "id": "NP_001004556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004556", "type": "external" } ], "gene_names_uniprotkb": "zgc:92161", "gene_names_refseq": "zgc:92161", "protein_names_uniprotkb": "Uncharacterized protein LOC447817; Zgc:92161", "protein_names_refseq": "uncharacterized protein LOC447817", "tax_id": 7955, "disease": "", "pathway": " (dre:447817)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC081613.1, EH484407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced NP_001004556.2., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N1V4", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IXF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXF6-1", "uniprot_id": [ { "id": "KAT2A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXF6", "type": "external" } ], "mass": 90624.0, "length": 795, "protein_name": "Histone acetyltransferase KAT2A", "gene_name": "kat2a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "kat2a", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone acetyltransferase KAT2A; 2.3.1.-; 2.3.1.48; Histone glutaryltransferase KAT2A; Histone succinyltransferase KAT2A; Lysine acetyltransferase 2A", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:555517); (R-DRE-5250924); (R-DRE-5689880)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "17997606;23594743;29174768;30424580", "class_list": "", "function": "Protein lysine acyltransferase that can act as a acetyltransferase, glutaryltransferasesucc, succinyltransferase or malonyltransferase, depending on the context (By similarity). Acts as a histone lysine succinyltransferase: catalyzes succinylation of histone H3 on 'Lys-79' (H3K79succ), with a maximum frequency around the transcription start sites of genes (By similarity). Succinylation of histones gives a specific tag for epigenetic transcription activation (By similarity). Association with the 2-oxoglutarate dehydrogenase complex, which provides succinyl-CoA, is required for histone succinylation (By similarity). In different complexes, functions either as an acetyltransferase (HAT) or as a succinyltransferase: in the SAGA and ATAC complexes, acts as a histone acetyltransferase (By similarity). Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles (By similarity). Has a a strong preference for acetylation of H3 at 'Lys-9' (H3K9ac) (By similarity). Also catalyzes acetylation of histone H1.4 (H1-4) at 'Lys-34' (H1.4K34ac), a modification enriched at promoters of active genes (By similarity). Acetylation of histones gives a specific tag for epigenetic transcription activation (By similarity). Also acetylates non-histone proteins, such as tbx5 (PubMed:29174768). Involved in heart and limb development by mediating acetylation of tbx5 (PubMed:29174768). Together with kat2b, required for growth and differentiation of craniofacial cartilage and bone by regulating acetylation of histone H3 at 'Lys-9' (H3K9ac) (PubMed:30424580). Also acts as a histone glutaryltransferase: catalyzes glutarylation of histone H4 on 'Lys-91' (H4K91glu), a mark that destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IN10;Q1L672", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.3.1.259", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.259", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.3.1.57", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.57", "type": "external" } ], "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0106078 histone succinyltransferase activity;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0004402 histone acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0000123 histone acetyltransferase complex;GO:0140672 ATAC complex", "go_biological_process": "GO:1903010 regulation of bone development;GO:0006338 chromatin remodeling;GO:0007507 heart development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048167 regulation of synaptic plasticity", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IXF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXG2-1", "uniprot_id": [ { "id": "A0A0R4IXG2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXG2", "type": "external" } ], "mass": 82755.0, "length": 723, "protein_name": "Amyloid beta (A4) precursor-like protein 1; Amyloid beta precursor like protein 1", "gene_name": "aplp1", "organism": "Zebrafish", "refseq_name": "amyloid beta precursor like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_001342921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001342921", "type": "external" } ], "gene_names_uniprotkb": "aplp1", "gene_names_refseq": "aplp1", "protein_names_uniprotkb": "Amyloid beta (A4) precursor-like protein 1; Amyloid beta precursor like protein 1", "protein_names_refseq": "amyloid beta precursor like protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:404233)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_001342921.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PZM7", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0046914 transition metal ion binding;GO:0031694 alpha-2A adrenergic receptor binding;GO:0031696 alpha-2C adrenergic receptor binding;GO:0031695 alpha-2B adrenergic receptor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0007409 axonogenesis;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IXG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXK5-1", "uniprot_id": [ { "id": "A0A0R4IXK5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXK5", "type": "external" } ], "mass": 8482.0, "length": 75, "protein_name": "Centromere protein W", "gene_name": "cenpw", "organism": "Zebrafish", "refseq_name": "centromere protein W isoform 1", "refseq_ac": [ { "id": "NP_001313366", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313366", "type": "external" } ], "gene_names_uniprotkb": "cenpw; si:ch211-195p4.3", "gene_names_refseq": "cenpw; si:ch211-195p4.3", "protein_names_uniprotkb": "Centromere protein W", "protein_names_refseq": "Cug2; centromere protein W isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:567320)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21838932;23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01024015.1, EX159231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1 and EH509864.1. On May 18, 2016 this sequence version replaced XP_709181.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Cug2 is required for normal mitosis during early neurogenesis and has functions in neuronal cell maintenance Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2M9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000776 kinetochore;GO:0005634 nucleus", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0007417 central nervous system development;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IXK5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXP5-1", "uniprot_id": [ { "id": "A0A0R4IXP5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXP5", "type": "external" } ], "mass": 17146.0, "length": 151, "protein_name": "Protein LBH-like; Si:ch1073-303d10.1", "gene_name": "si:ch1073-303d10.1", "organism": "Zebrafish", "refseq_name": "protein LBH-like", "refseq_ac": [ { "id": "NP_001373650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373650", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-303d10.1", "gene_names_refseq": "si:ch1073-303d10.1", "protein_names_uniprotkb": "Protein LBH-like; Si:ch1073-303d10.1", "protein_names_refseq": "proline-, glutamic acid- and leucine-rich protein 1-like; protein LBH-like", "tax_id": 7955, "disease": "", "pathway": " (dre:558565)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588714.23308109.1, GDQH01037321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Sep 2, 2020 this sequence version replaced XP_704936.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T8I3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IXP5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXS6-1", "uniprot_id": [ { "id": "A0A0R4IXS6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXS6", "type": "external" } ], "mass": 34508.0, "length": 304, "protein_name": "PI-PLC X domain-containing protein 1-like; Zgc:64065", "gene_name": "LOC100151335", "organism": "Zebrafish", "refseq_name": "PI-PLC X domain-containing protein 1-like", "refseq_ac": [ { "id": "NP_958491", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958491", "type": "external" } ], "gene_names_uniprotkb": "LOC100151335; zgc:64065", "gene_names_refseq": "zgc:64065", "protein_names_uniprotkb": "PI-PLC X domain-containing protein 1-like; Zgc:64065", "protein_names_refseq": "PI-PLC X domain-containing protein 1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100151335); (dre:393379)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC054605.1, CA473368.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC054605.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7XJH6;Q7T2C3", "ec_number_list": [], "go_molecular_function": "GO:0008081 phosphoric diester hydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IXS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXS9-1", "uniprot_id": [ { "id": "A0A0R4IXS9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXS9", "type": "external" } ], "mass": 126829.0, "length": 1121, "protein_name": "Si:ch211-243p7.3", "gene_name": "si:ch211-243p7.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-243p7.3 isoform X1", "refseq_ac": [ { "id": "XP_009302544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302544", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-243p7.3", "gene_names_refseq": "si:ch211-243p7.3", "protein_names_uniprotkb": "Si:ch211-243p7.3", "protein_names_refseq": "uncharacterized protein si:ch211-243p7.3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101885951)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B577", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IXS9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXU5-1", "uniprot_id": [ { "id": "A0A0R4IXU5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXU5", "type": "external" } ], "mass": 9353.0, "length": 87, "protein_name": "Lymphocyte antigen 6 complex, locus D precursor; Si:ch211-207n23.2", "gene_name": "si:ch211-207n23.2", "organism": "Zebrafish", "refseq_name": "lymphocyte antigen 6 complex, locus D precursor", "refseq_ac": [ { "id": "NP_001373155", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373155", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-207n23.2; ly6d", "gene_names_refseq": "ly6d; si:ch211-207n23.2", "protein_names_uniprotkb": "Lymphocyte antigen 6 complex, locus D precursor; Si:ch211-207n23.2", "protein_names_refseq": "lymphocyte antigen 6 complex, locus D precursor; lymphocyte antigen 6 complex, locus D", "tax_id": 7955, "disease": "", "pathway": " (dre:559783)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH468630.1, EH442753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA4476732 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 15, 2020 this sequence version replaced XP_005157804.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B4M7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IXU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IXX0-1", "uniprot_id": [ { "id": "A0A0R4IXX0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IXX0", "type": "external" } ], "mass": 414358.0, "length": 3609, "protein_name": "Dystrophin", "gene_name": "dmd", "organism": "Zebrafish", "refseq_name": "dystrophin isoform 1", "refseq_ac": [ { "id": "NP_001313616", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313616", "type": "external" } ], "gene_names_uniprotkb": "dmd; Dp71; cb664; im:6911785; zfDYS; zgc:110165", "gene_names_refseq": "Dp71; cb664; dmd; im:6911785; zfDYS; zgc:110165", "protein_names_uniprotkb": "Dystrophin", "protein_names_refseq": "Duchenne muscular dystrophy; dystrophin isoform 1; sapje-like; sapje; sap", "tax_id": 7955, "disease": "X-linked dilated cardiomyopathy (Disease Ontology:DOID:0110461); intellectual disability (Disease Ontology:DOID:1059); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); dilated cardiomyopathy (Disease Ontology:DOID:12930); cognitive disorder (Disease Ontology:DOID:1561); Becker muscular dystrophy (Disease Ontology:DOID:9883); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (dre:83773); (R-DRE-390522)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "12091319;12620966;12659844;14573513;23594743;36833417;36837851;36869044;37092478;38431640;9007258", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. On May 24, 2016 this sequence version replaced XP_009304312.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Analysis of the dystrophin associated protein complex in zebrafish, [RefSeq, PubMed]; Data suggest that the progressive muscle degeneration phenotype of dystrophin mutant zebrafish embryos is caused by the failure of embryonic muscle end attachments., [RefSeq, PubMed]; May play a role in anchoring the cytoskeleton to the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3J4", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0045211 postsynaptic membrane;GO:0042383 sarcolemma", "go_biological_process": "GO:0007525 somatic muscle development;GO:0006936 muscle contraction;GO:0007517 muscle organ development;GO:0048741 skeletal muscle fiber development;GO:0045214 sarcomere organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IXX0-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY00-1", "uniprot_id": [ { "id": "A0A0R4IY00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY00", "type": "external" } ], "mass": 38817.0, "length": 345, "protein_name": "Large ribosomal subunit protein uL3m", "gene_name": "mrpl3", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mrpl3; fj61d01; wu:fj61d01; zgc:66423", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL3m; 39S ribosomal protein L3, mitochondrial", "protein_names_refseq": "", "tax_id": 7955, "disease": "combined oxidative phosphorylation deficiency 9 (Disease Ontology:DOID:0111472)", "pathway": " (dre:336283); (R-DRE-5389840); (R-DRE-5419276); (R-DRE-9937383)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6E9", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IY00-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY06-1", "uniprot_id": [ { "id": "PLAT1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY06", "type": "external" } ], "mass": 19845.0, "length": 179, "protein_name": "Phospholipase A and acyltransferase 1", "gene_name": "plaat1", "organism": "Zebrafish", "refseq_name": "phospholipase A and acyltransferase 1", "refseq_ac": [ { "id": "NP_001002590", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002590", "type": "external" } ], "gene_names_uniprotkb": "plaat1; hrasls; zgc:92715", "gene_names_refseq": "hrasls; plaat1; zgc:92715", "protein_names_uniprotkb": "Phospholipase A and acyltransferase 1; 2.3.1.-; 3.1.1.32; 3.1.1.4", "protein_names_refseq": "HRAS-like suppressor; phospholipase A and acyltransferase 1", "tax_id": 7955, "disease": "", "pathway": " (dre:436863); (R-DRE-1482839)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;33854238", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC076195.1, CN506292.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076195.1. On Oct 7, 2011 this sequence version replaced NP_001002590.1., [RefSeq]; Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs) (By similarity). Required for complete organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light (PubMed:33854238). Organelle membrane degradation is probably catalyzed by the phospholipase activity (By similarity) (PubMed:33854238)., [UniProtKB, PubMed, UniProtKB]; Organelle degradation in the lens by PLAAT phospholipases., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6DGY9", "ec_number_list": [ { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" } ], "go_molecular_function": "GO:0004623 phospholipase A2 activity;GO:0008970 phospholipase A1 activity;GO:0016410 N-acyltransferase activity;GO:0016787 hydrolase activity;GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:1903008 organelle disassembly;GO:0016042 lipid catabolic process;GO:0070306 lens fiber cell differentiation;GO:0070292 N-acylphosphatidylethanolamine metabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IY06-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY33-1", "uniprot_id": [ { "id": "A0A0R4IY33_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY33", "type": "external" } ], "mass": 50562.0, "length": 454, "protein_name": "Target of Myb protein 1 isoform 1; Target of myb1 membrane-trafficking protein", "gene_name": "tom1", "organism": "Zebrafish", "refseq_name": "target of Myb1 membrane trafficking protein isoform 1", "refseq_ac": [ { "id": "NP_001338580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338580", "type": "external" } ], "gene_names_uniprotkb": "tom1; Tom1l2", "gene_names_refseq": "Tom1l2; tom1", "protein_names_uniprotkb": "Target of Myb protein 1 isoform 1; Target of myb1 membrane-trafficking protein", "protein_names_refseq": "target of Myb1 membrane trafficking protein isoform 1", "tax_id": 7955, "disease": "immunodeficiency 85 (Disease Ontology:DOID:0061055)", "pathway": " (dre:553244); (R-DRE-6798695)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "18971206;23594743;27189481;27462902", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC139585.1, GFIL01041658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH551587.1, EH589099.1, BC078346.1 and JBMGRA010000003.1. On May 18, 2017 this sequence version replaced XP_688045.6. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9P8", "ec_number_list": [], "go_molecular_function": "GO:0030276 clathrin binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005768 endosome;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IY33-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY52-1", "uniprot_id": [ { "id": "A0A0R4IY52_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY52", "type": "external" } ], "mass": 82850.0, "length": 724, "protein_name": "Vacuolar protein sorting-associated protein 52 homolog", "gene_name": "vps52", "organism": "Zebrafish", "refseq_name": "vacuolar protein sorting-associated protein 52 homolog isoform X1", "refseq_ac": [ { "id": "XP_068071368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071368", "type": "external" } ], "gene_names_uniprotkb": "vps52", "gene_names_refseq": "vps52", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 52 homolog", "protein_names_refseq": "vacuolar protein sorting-associated protein 52 homolog isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:556724)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AK60", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding", "go_cellular_component": "GO:0000938 GARP complex;GO:0005829 cytosol;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0015031 protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0032456 endocytic recycling;GO:0007041 lysosomal transport;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IY52-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY89-1", "uniprot_id": [ { "id": "A0A0R4IY89_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY89", "type": "external" } ], "mass": 30799.0, "length": 278, "protein_name": "Homeobox protein Nkx-6.2; NK6 homeobox 2", "gene_name": "nkx6.2", "organism": "Zebrafish", "refseq_name": "homeobox protein Nkx-6.2", "refseq_ac": [ { "id": "NP_001129256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129256", "type": "external" } ], "gene_names_uniprotkb": "nkx6.2", "gene_names_refseq": "nkx6.2", "protein_names_uniprotkb": "Homeobox protein Nkx-6.2; NK6 homeobox 2", "protein_names_refseq": "NK6 transcription factor related, locus 2; homeobox protein Nkx-6.2", "tax_id": 7955, "disease": "spastic ataxia 8 (Disease Ontology:DOID:0080252)", "pathway": " (dre:565782)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "17307034;17376808;17994542;18062957;18499750;23594743;31375626;32867764;33449448;34473348;35060900", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.10043658.1, SRR32588725.15264684.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1 and EH578673.1. On Oct 11, 2008 this sequence version replaced XP_694144.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Study shows that zebrafish primary motoneurons express two related transcription factors Nkx6.1 and Nkx6.2; in their absence, the CaP motoneuron subtype develops normally, whereas the MiP motoneuron subtype develops a interneuron-like morphology., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NLG5", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0021522 spinal cord motor neuron differentiation;GO:0031018 endocrine pancreas development;GO:0003309 type B pancreatic cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IY89-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY94-1", "uniprot_id": [ { "id": "A0A0R4IY94_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY94", "type": "external" } ], "mass": 30583.0, "length": 279, "protein_name": "Retbindin isoform X1; Zgc:109949", "gene_name": "rtbdn", "organism": "Zebrafish", "refseq_name": "retbindin isoform X1", "refseq_ac": [ { "id": "XP_009297376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297376", "type": "external" } ], "gene_names_uniprotkb": "rtbdn; zgc:109949", "gene_names_refseq": "rtbdn; zgc:109949", "protein_names_uniprotkb": "Retbindin isoform X1; Zgc:109949", "protein_names_refseq": "retbindin isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:553764)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;25436775;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B829", "ec_number_list": [], "go_molecular_function": "GO:0032217 riboflavin transmembrane transporter activity;GO:1902444 riboflavin binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IY94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IY96-1", "uniprot_id": [ { "id": "A0A0R4IY96_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IY96", "type": "external" } ], "mass": 111265.0, "length": 1023, "protein_name": "Integrator complex subunit 5", "gene_name": "ints5", "organism": "Zebrafish", "refseq_name": "integrator complex subunit 5", "refseq_ac": [ { "id": "XP_693062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693062", "type": "external" } ], "gene_names_uniprotkb": "ints5", "gene_names_refseq": "ints5", "protein_names_uniprotkb": "Integrator complex subunit 5", "protein_names_refseq": "integrator complex subunit 5", "tax_id": 7955, "disease": "", "pathway": " (dre:564642); (R-DRE-6807505)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_693062.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TB96", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0032039 integrator complex", "go_biological_process": "GO:0043484 regulation of RNA splicing;GO:0034472 snRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IY96-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYB8-1", "uniprot_id": [ { "id": "A0A0R4IYB8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYB8", "type": "external" } ], "mass": 127887.0, "length": 1182, "protein_name": "Tyrosine-protein kinase", "gene_name": "abl2", "organism": "Zebrafish", "refseq_name": "tyrosine-protein kinase ABL2 isoform X1", "refseq_ac": [ { "id": "XP_005166946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166946", "type": "external" } ], "gene_names_uniprotkb": "abl2; cb272", "gene_names_refseq": "abl2; cb272", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase ABL2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:570636); (R-DRE-9013149); (R-DRE-9013423)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "23594743;24002024;26469318;27189481;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BEE2", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0030145 manganese ion binding;GO:0004713 protein tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0010976 positive regulation of neuron projection development;GO:0030155 regulation of cell adhesion;GO:2000145 regulation of cell motility", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IYB8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYD3-1", "uniprot_id": [ { "id": "A0A0R4IYD3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYD3", "type": "external" } ], "mass": 95658.0, "length": 871, "protein_name": "WD repeat domain 47b; WD repeat-containing protein 47b", "gene_name": "wdr47b", "organism": "Zebrafish", "refseq_name": "WD repeat-containing protein 47b", "refseq_ac": [ { "id": "NP_001188350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188350", "type": "external" } ], "gene_names_uniprotkb": "wdr47b", "gene_names_refseq": "wdr47b", "protein_names_uniprotkb": "WD repeat domain 47b; WD repeat-containing protein 47b", "protein_names_refseq": "WD repeat-containing protein 47b", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01043307.1, GDQH01030059.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505390, SAMEA4476738 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1, EH456002.1, EH481738.1, EH438155.1 and EH464109.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1N1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IYD3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYE6-1", "uniprot_id": [ { "id": "A0A0R4IYE6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYE6", "type": "external" } ], "mass": 92655.0, "length": 830, "protein_name": "SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4 isoform X1", "gene_name": "slitrk4", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "slitrk4", "gene_names_refseq": "", "protein_names_uniprotkb": "SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4 isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:558123)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QPE0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0016020 membrane", "go_biological_process": "GO:0007409 axonogenesis;GO:0051965 positive regulation of synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IYE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYF5-1", "uniprot_id": [ { "id": "A0A0R4IYF5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYF5", "type": "external" } ], "mass": 20491.0, "length": 174, "protein_name": "Si:zfos-1056e6.1; Uncharacterized protein LOC107988029", "gene_name": "si:zfos-1056e6.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC107988029", "refseq_ac": [ { "id": "NP_001315034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315034", "type": "external" } ], "gene_names_uniprotkb": "si:zfos-1056e6.1", "gene_names_refseq": "si:zfos-1056e6.1", "protein_names_uniprotkb": "Si:zfos-1056e6.1; Uncharacterized protein LOC107988029", "protein_names_refseq": "uncharacterized protein LOC107988029", "tax_id": 7955, "disease": "", "pathway": " (dre:107988029)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH503890.1, EH487514.1 and EH513905.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3J7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IYF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYG0-1", "uniprot_id": [ { "id": "A0A0R4IYG0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYG0", "type": "external" } ], "mass": 27164.0, "length": 250, "protein_name": "Fibronectin type III domain-containing protein 10; Si:zfos-1324h11.5", "gene_name": "fndc10", "organism": "Zebrafish", "refseq_name": "fibronectin type III domain-containing protein 10", "refseq_ac": [ { "id": "XP_005168340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168340", "type": "external" } ], "gene_names_uniprotkb": "fndc10", "gene_names_refseq": "fndc10", "protein_names_uniprotkb": "Fibronectin type III domain-containing protein 10; Si:zfos-1324h11.5", "protein_names_refseq": "fibronectin type III domain-containing protein 10", "tax_id": 7955, "disease": "", "pathway": " (dre:101885825)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG78", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IYG0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYS4-1", "uniprot_id": [ { "id": "A0A0R4IYS4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYS4", "type": "external" } ], "mass": 107363.0, "length": 970, "protein_name": "Protocadherin-8; Si:ch211-199f5.1", "gene_name": "pcdh8.2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "pcdh8.2; si:ch211-199f5.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protocadherin-8; Si:ch211-199f5.1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100002026)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PSL2", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IYS4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYT1-1", "uniprot_id": [ { "id": "A0A0R4IYT1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYT1", "type": "external" } ], "mass": 87397.0, "length": 770, "protein_name": "SUMO-interacting motif-containing protein 1; Si:ch211-199b20.3", "gene_name": "simc1", "organism": "Zebrafish", "refseq_name": "SUMO-interacting motif-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_001922583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922583", "type": "external" } ], "gene_names_uniprotkb": "simc1", "gene_names_refseq": "simc1", "protein_names_uniprotkb": "SUMO-interacting motif-containing protein 1; Si:ch211-199b20.3", "protein_names_refseq": "SUMO-interacting motif-containing protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100150204)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001922583.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QV88", "ec_number_list": [], "go_molecular_function": "GO:0032184 SUMO polymer binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IYT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYT8-1", "uniprot_id": [ { "id": "A0A0R4IYT8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYT8", "type": "external" } ], "mass": 67566.0, "length": 596, "protein_name": "Carboxylic ester hydrolase", "gene_name": "si:ch211-71n6.4", "organism": "Zebrafish", "refseq_name": "para-nitrobenzyl esterase", "refseq_ac": [ { "id": "XP_009292113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292113", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-71n6.4", "gene_names_refseq": "si:ch211-71n6.4", "protein_names_uniprotkb": "Carboxylic ester hydrolase; 3.1.1.-", "protein_names_refseq": "para-nitrobenzyl esterase", "tax_id": 7955, "disease": "", "pathway": " (dre:100148657)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AV48", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IYT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYX6-1", "uniprot_id": [ { "id": "Z687A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYX6", "type": "external" } ], "mass": 134592.0, "length": 1246, "protein_name": "Zinc finger protein 687a", "gene_name": "znf687a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "znf687a; si:dkey-71b5.10", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 687a", "protein_names_refseq": "", "tax_id": 7955, "disease": "Paget's disease of bone 6 (Disease Ontology:DOID:0081369)", "pathway": " (dre:562791)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;26849110", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IYX6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IYY2-1", "uniprot_id": [ { "id": "A0A0R4IYY2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IYY2", "type": "external" } ], "mass": 43039.0, "length": 377, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "ube2q1", "organism": "Zebrafish", "refseq_name": "ubiquitin-conjugating enzyme E2 Q1 isoform X1", "refseq_ac": [ { "id": "XP_005173748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173748", "type": "external" } ], "gene_names_uniprotkb": "ube2q1; wu:fi42b06; zgc:110254", "gene_names_refseq": "ube2q1; wu:fi42b06; zgc:110254", "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 2.3.2.23", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 Q1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:553603)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16109975;23594743;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKZ3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IYY2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZ38-1", "uniprot_id": [ { "id": "A0A0R4IZ38_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZ38", "type": "external" } ], "mass": 32443.0, "length": 288, "protein_name": "Mucin-1", "gene_name": "si:dkeyp-92c9.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkeyp-92c9.4", "refseq_ac": [ { "id": "XP_003200649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200649", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-92c9.4", "gene_names_refseq": "si:dkeyp-92c9.4", "protein_names_uniprotkb": "Mucin-1", "protein_names_refseq": "uncharacterized protein si:dkeyp-92c9.4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200649.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RMS6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZ38-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZ84-1", "uniprot_id": [ { "id": "EST1A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZ84", "type": "external" } ], "mass": 172241.0, "length": 1544, "protein_name": "Telomerase-binding protein EST1A", "gene_name": "smg6", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "smg6; est1a; si:dkey-16f21.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Telomerase-binding protein EST1A; 3.1.-.-; Ever shorter telomeres 1A; Nonsense mediated mRNA decay factor SMG6; Smg-6 homolog", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100334020); (R-DRE-975957)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "19414594;21168434;23594743;26301497;32571908", "class_list": "", "function": "Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini (By similarity). Required for normal embryonic development (PubMed:19414594)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]; Plays a role in nonsense-mediated mRNA decay., [UniProtKB, UniProtKB]; Plays a role in nonsense-mediated mRNA decay. Is thought to provide a link to the mRNA degradation machinery as it has endonuclease activity required to initiate NMD. Degrades single-stranded RNA (ssRNA), but not ssDNA or dsRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "C5J7W9", "ec_number_list": [ { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0042162 telomeric DNA binding;GO:0004519 endonuclease activity;GO:0070034 telomerase RNA binding;GO:0030145 manganese ion binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005697 telomerase holoenzyme complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0043009 chordate embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IZ84-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZB2-1", "uniprot_id": [ { "id": "A0A0R4IZB2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZB2", "type": "external" } ], "mass": 18038.0, "length": 169, "protein_name": "Si:ch211-161c3.5; Uncharacterized protein C3orf18 homolog isoform X1", "gene_name": "si:ch211-161c3.5", "organism": "Zebrafish", "refseq_name": "uncharacterized protein C3orf18 homolog isoform X1", "refseq_ac": [ { "id": "XP_009301000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301000", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-161c3.5", "gene_names_refseq": "si:ch211-161c3.5", "protein_names_uniprotkb": "Si:ch211-161c3.5; Uncharacterized protein C3orf18 homolog isoform X1", "protein_names_refseq": "uncharacterized protein C3orf18 homolog isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101883575)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BAN1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZB2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZC9-1", "uniprot_id": [ { "id": "A0A0R4IZC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZC9", "type": "external" } ], "mass": 56694.0, "length": 496, "protein_name": "Lysophospholipid acyltransferase 1; Membrane-bound O-acyltransferase domain-containing 1", "gene_name": "mboat1", "organism": "Zebrafish", "refseq_name": "lysophospholipid acyltransferase 1", "refseq_ac": [ { "id": "NP_001007397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007397", "type": "external" } ], "gene_names_uniprotkb": "mboat1; fc11c04; wu:fc11c04; wu:fq24h09; zgc:101798", "gene_names_refseq": "fc11c04; mboat1; wu:fc11c04; wu:fq24h09; zgc:101798", "protein_names_uniprotkb": "Lysophospholipid acyltransferase 1; Membrane-bound O-acyltransferase domain-containing 1", "protein_names_refseq": "lysophospholipid acyltransferase 1", "tax_id": 7955, "disease": "", "pathway": " (dre:572841); (R-DRE-1482801); (R-DRE-1482839)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL935025.11. On or before Sep 2, 2007 this sequence version replaced XP_707374.2, NP_001007397.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N3H2", "ec_number_list": [], "go_molecular_function": "GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030258 lipid modification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IZC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZD4-1", "uniprot_id": [ { "id": "A0A0R4IZD4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZD4", "type": "external" } ], "mass": 77453.0, "length": 709, "protein_name": "Si:dkeyp-72e1.9; Syntaxin-binding protein 4 isoform X1", "gene_name": "si:dkeyp-72e1.9", "organism": "Zebrafish", "refseq_name": "syntaxin-binding protein 4 isoform X1", "refseq_ac": [ { "id": "XP_691844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691844", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-72e1.9", "gene_names_refseq": "si:dkeyp-72e1.9", "protein_names_uniprotkb": "Si:dkeyp-72e1.9; Syntaxin-binding protein 4 isoform X1", "protein_names_refseq": "syntaxin-binding protein 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:563388)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_691844.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T637", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZD4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZE2-1", "uniprot_id": [ { "id": "A0A0R4IZE2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZE2", "type": "external" } ], "mass": 111876.0, "length": 1003, "protein_name": "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1; Hermansky-Pudlak syndrome 3 protein", "gene_name": "hps3", "organism": "Zebrafish", "refseq_name": "BLOC-2 complex member HPS3", "refseq_ac": [ { "id": "NP_001180471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180471", "type": "external" } ], "gene_names_uniprotkb": "hps3; zgc:152969", "gene_names_refseq": "hps3; zgc:152969", "protein_names_uniprotkb": "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1; Hermansky-Pudlak syndrome 3 protein", "protein_names_refseq": "BLOC-2 complex member HPS3; Hermansky-Pudlak syndrome 3", "tax_id": 7955, "disease": "Hermansky-Pudlak syndrome 3 (Disease Ontology:DOID:0060541); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dre:777758)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23594743;23893484;26469318;27189481;31142542;31776394", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01012840.1, GDQH01015781.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NW15", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IZE2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZE6-1", "uniprot_id": [ { "id": "A0A0R4IZE6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZE6", "type": "external" } ], "mass": 38040.0, "length": 338, "protein_name": "D-aspartate oxidase", "gene_name": "ddo", "organism": "Zebrafish", "refseq_name": "D-aspartate oxidase precursor", "refseq_ac": [ { "id": "NP_001274017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001274017", "type": "external" } ], "gene_names_uniprotkb": "ddo; zgc:172341", "gene_names_refseq": "ddo; zgc:172341", "protein_names_uniprotkb": "D-aspartate oxidase; 1.4.3.1", "protein_names_refseq": "D-aspartate oxidase precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:565385); (R-DRE-389661)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "23594743;27189481;34481069;35295584", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01046314.1, GDQH01008552.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Nov 26, 2013 this sequence version replaced XP_002665184.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Selectively catalyzes the oxidative deamination of acidic amino acids. Suppresses the level of D-aspartate in the brain, an amino acid that can act as an agonist for glutamate receptors. Protects the organism from the toxicity of D-amino acids. May also function in the intestine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P573", "ec_number_list": [ { "id": "1.4.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.1", "type": "external" } ], "go_molecular_function": "GO:0008445 D-aspartate oxidase activity;GO:0071949 FAD binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0019478 D-amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IZE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZE7-1", "uniprot_id": [ { "id": "A0A0R4IZE7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZE7", "type": "external" } ], "mass": 37203.0, "length": 330, "protein_name": "PAK4-inhibitor INKA2", "gene_name": "inka2", "organism": "Zebrafish", "refseq_name": "PAK4-inhibitor INKA2 isoform X1", "refseq_ac": [ { "id": "XP_005167187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167187", "type": "external" } ], "gene_names_uniprotkb": "inka2", "gene_names_refseq": "inka2", "protein_names_uniprotkb": "PAK4-inhibitor INKA2; PAK4-inhibitor inka2", "protein_names_refseq": "PAK4-inhibitor INKA2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101886856)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BF34", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030291 protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZE7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZF6-1", "uniprot_id": [ { "id": "A0A0R4IZF6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZF6", "type": "external" } ], "mass": 66528.0, "length": 616, "protein_name": "AT-rich interactive domain-containing protein 3", "gene_name": "arid3b", "organism": "Zebrafish", "refseq_name": "AT-rich interactive domain-containing protein 3B", "refseq_ac": [ { "id": "NP_001076471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076471", "type": "external" } ], "gene_names_uniprotkb": "arid3b; wu:fc16g09; wu:fc87c02; zgc:158235", "gene_names_refseq": "arid3b; wu:fc16g09; wu:fc87c02; zgc:158235", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 3; ARID domain-containing protein", "protein_names_refseq": "AT rich interactive domain 3B (BRIGHT-like); AT rich interactive domain 3B (Bright like); AT-rich interactive domain-containing protein 3B", "tax_id": 7955, "disease": "", "pathway": " (dre:571249)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;24240475;26776728;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019717.1, BC131867.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Jun 15, 2024 this sequence version replaced XP_005163185.1, NP_001076471.1., [RefSeq]; Transcription factor., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BA85", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IZF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZG6-1", "uniprot_id": [ { "id": "A0A0R4IZG6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZG6", "type": "external" } ], "mass": 55402.0, "length": 512, "protein_name": "Polypyrimidine tract-binding protein 2a; Uncharacterized protein LOC541437", "gene_name": "ptbp2a", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC541437", "refseq_ac": [ { "id": "NP_001315358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315358", "type": "external" } ], "gene_names_uniprotkb": "ptbp2a; zgc:113074", "gene_names_refseq": "ptbp2a; zgc:113074", "protein_names_uniprotkb": "Polypyrimidine tract-binding protein 2a; Uncharacterized protein LOC541437", "protein_names_refseq": "uncharacterized protein LOC541437", "tax_id": 7955, "disease": "", "pathway": " (dre:541437)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "22855693;23594743;25534026;27189481;31227602;8373170", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031666.1, SRR26395014.839265.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jun 16, 2016 this sequence version replaced XP_009295819.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3W0", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IZG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZJ0-1", "uniprot_id": [ { "id": "A0A0R4IZJ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZJ0", "type": "external" } ], "mass": 7197.0, "length": 64, "protein_name": "C-x(9)-C motif-containing 4 homolog (S. cerevisiae); Cx9C motif-containing protein 4", "gene_name": "cmc4", "organism": "Zebrafish", "refseq_name": "cx9C motif-containing protein 4", "refseq_ac": [ { "id": "NP_001289931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289931", "type": "external" } ], "gene_names_uniprotkb": "cmc4", "gene_names_refseq": "cmc4", "protein_names_uniprotkb": "C-x(9)-C motif-containing 4 homolog (S. cerevisiae); Cx9C motif-containing protein 4", "protein_names_refseq": "cx9C motif-containing protein 4; mtcp1nb", "tax_id": 7955, "disease": "", "pathway": " (dre:100333981)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21596366;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH487841.1, EH500071.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH487841.1 and EH526314.1. On Dec 11, 2014 this sequence version replaced XP_005170401.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1P4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IZJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZJ3-1", "uniprot_id": [ { "id": "A0A0R4IZJ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZJ3", "type": "external" } ], "mass": 34665.0, "length": 301, "protein_name": "Gastrula zinc finger protein XlCGF8.2DB; Si:ch211-161m3.4", "gene_name": "si:ch211-161m3.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-161m3.4 isoform X2", "refseq_ac": [ { "id": "XP_017210897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210897", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-161m3.4", "gene_names_refseq": "si:ch211-161m3.4", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF8.2DB; Si:ch211-161m3.4", "protein_names_refseq": "uncharacterized protein si:ch211-161m3.4 isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:108183503)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YXD3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZL6-1", "uniprot_id": [ { "id": "A0A0R4IZL6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZL6", "type": "external" } ], "mass": 44228.0, "length": 392, "protein_name": "Ras-related GTP-binding protein", "gene_name": "rragcb", "organism": "Zebrafish", "refseq_name": "Ras-related GTP binding Cb", "refseq_ac": [ { "id": "NP_001093538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093538", "type": "external" } ], "gene_names_uniprotkb": "rragcb; si:dkey-218f9.9", "gene_names_refseq": "rragcb; si:dkey-218f9.9", "protein_names_uniprotkb": "Ras-related GTP-binding protein", "protein_names_refseq": "Ras-related GTP binding Cb", "tax_id": 7955, "disease": "", "pathway": " (dre:100000325)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12618376;21873635;23594743;30402654", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01034078.1, GDQQ01027158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505387, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Jul 26, 2007 this sequence version replaced XP_001336060.1., [RefSeq]; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NE38", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046982 protein heterodimerization activity;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005764 lysosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0010507 negative regulation of autophagy;GO:0009267 cellular response to starvation;GO:0034198 cellular response to amino acid starvation;GO:0071230 cellular response to amino acid stimulus", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IZL6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZN1-1", "uniprot_id": [ { "id": "A0A0R4IZN1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZN1", "type": "external" } ], "mass": 63673.0, "length": 555, "protein_name": "Bloodthirsty-related gene family, member 24; E3 ubiquitin-protein ligase TRIM39", "gene_name": "btr24", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase TRIM39 isoform X1", "refseq_ac": [ { "id": "XP_017207881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207881", "type": "external" } ], "gene_names_uniprotkb": "btr24", "gene_names_refseq": "btr24", "protein_names_uniprotkb": "Bloodthirsty-related gene family, member 24; E3 ubiquitin-protein ligase TRIM39", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM39 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100000030); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YWJ5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZQ0-1", "uniprot_id": [ { "id": "A0A0R4IZQ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZQ0", "type": "external" } ], "mass": 22922.0, "length": 207, "protein_name": "Cellular repressor of E1A-stimulated genes 1; Protein CREG1 precursor", "gene_name": "creg1", "organism": "Zebrafish", "refseq_name": "protein CREG1 precursor", "refseq_ac": [ { "id": "NP_001307134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307134", "type": "external" } ], "gene_names_uniprotkb": "creg1; zgc:158288", "gene_names_refseq": "creg1; zgc:158288", "protein_names_uniprotkb": "Cellular repressor of E1A-stimulated genes 1; Protein CREG1 precursor", "protein_names_refseq": "protein CREG1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:791208)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23072875;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395017.1443220.1, SRR26395050.69394.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Feb 13, 2016 this sequence version replaced XP_005170899.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2E6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IZQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZR5-1", "uniprot_id": [ { "id": "A0A0R4IZR5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZR5", "type": "external" } ], "mass": 146551.0, "length": 1276, "protein_name": "Cohesin subunit SA", "gene_name": "stag2b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "stag2b", "gene_names_refseq": "", "protein_names_uniprotkb": "Cohesin subunit SA; SCC3 homolog; Stromal antigen", "protein_names_refseq": "", "tax_id": 7955, "disease": "Holoprosencephaly 13, X-linked (Disease Ontology:DOID:0060954); Mullegama-Klein-Martinez syndrome (Disease Ontology:DOID:0111845)", "pathway": " (dre:560751); (R-DRE-2467813); (R-DRE-2468052); (R-DRE-2470946); (R-DRE-2500257); (R-DRE-3108214)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q574", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin;GO:0008278 cohesin complex", "go_biological_process": "GO:1901532 regulation of hematopoietic progenitor cell differentiation;GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007062 sister chromatid cohesion;GO:2001212 regulation of vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZR5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZT6-1", "uniprot_id": [ { "id": "A0A0R4IZT6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZT6", "type": "external" } ], "mass": 37083.0, "length": 323, "protein_name": "Serine/threonine-protein phosphatase", "gene_name": "ppp1cc", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein phosphatase PP1-gamma catalytic subunit A", "refseq_ac": [ { "id": "XP_700468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700468", "type": "external" } ], "gene_names_uniprotkb": "ppp1cc", "gene_names_refseq": "ppp1cc", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase; 3.1.3.16", "protein_names_refseq": "serine/threonine-protein phosphatase PP1-gamma catalytic subunit A", "tax_id": 7955, "disease": "", "pathway": " (dre:571753); (R-DRE-141430); (R-DRE-141444); (R-DRE-180024); (R-DRE-2467813); (R-DRE-2500257); (R-DRE-5663220); (R-DRE-5673000); (R-DRE-9770562)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_700468.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T728", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0032154 cleavage furrow", "go_biological_process": "GO:0001525 angiogenesis;GO:0051301 cell division;GO:0005977 glycogen metabolic process;GO:0042752 regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZT6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZU6-1", "uniprot_id": [ { "id": "A0A0R4IZU6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZU6", "type": "external" } ], "mass": 71780.0, "length": 653, "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1; Si:dkey-34d22.1", "gene_name": "si:dkey-34d22.1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:dkey-34d22.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Discoidin, CUB and LCCL domain-containing protein 1; Si:dkey-34d22.1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100535421)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B1V4", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IZW2-1", "uniprot_id": [ { "id": "A0A0R4IZW2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IZW2", "type": "external" } ], "mass": 77884.0, "length": 725, "protein_name": "Protein ENTREP3 isoform X1; Si:dkey-7f3.9", "gene_name": "fam189b", "organism": "Zebrafish", "refseq_name": "protein ENTREP3 isoform X1", "refseq_ac": [ { "id": "XP_005158202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158202", "type": "external" } ], "gene_names_uniprotkb": "fam189b", "gene_names_refseq": "fam189b", "protein_names_uniprotkb": "Protein ENTREP3 isoform X1; Si:dkey-7f3.9", "protein_names_refseq": "protein ENTREP3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101882768)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B4Z3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IZW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J1Z0-1", "uniprot_id": [ { "id": "A0A0R4J1Z0_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0R4J1Z0", "type": "external" } ], "mass": 37011.0, "length": 331, "protein_name": "MAS-related GPR, member A2A", "gene_name": "Mrgpra2a", "organism": "Mouse", "refseq_name": "MAS-related GPR, member A2A isoform 2", "refseq_ac": [ { "id": "NP_001166059", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166059", "type": "external" } ], "gene_names_uniprotkb": "Mrgpra2a", "gene_names_refseq": "Mrga2; Mrgpra2a; Mrgpra2", "protein_names_uniprotkb": "MAS-related GPR, member A2A", "protein_names_refseq": "MAS-related GPR, member A2A isoform 2; Mas-related G-protein coupled receptor member A2", "tax_id": 10090, "disease": "", "pathway": " (mmu:668727)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21750661;35882236", "class_list": "", "function": "Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4J1Z0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "uniprot_id": [ { "id": "A0A0R4J2B9_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0R4J2B9", "type": "external" } ], "mass": 57869.0, "length": 498, "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "organism": "Mouse", "refseq_name": "germ cell-less protein-like 2", "refseq_ac": [ { "id": "NP_001257596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257596", "type": "external" } ], "gene_names_uniprotkb": "Btbd35f23", "gene_names_refseq": "Btbd35f1; Btbd35f23; Gm21950; Gmcl1l; Gmcl1p1; Gmcl2; Mgclh", "protein_names_uniprotkb": "BTB domain containing 35, family member 23", "protein_names_refseq": "BTB domain containing 35, family member 1; Germ cell-less protein-like 1-like; germ cell-less haploid specific; germ cell-less protein-like 2", "tax_id": 10090, "disease": "", "pathway": " (mmu:100861966)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007281 germ cell development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4J2B9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J720-1", "uniprot_id": [ { "id": "A0A0R4J720_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4J720", "type": "external" } ], "mass": 60655.0, "length": 551, "protein_name": "Major facilitator superfamily domain-containing 2B; Major facilitator superfamily domain-containing protein 2B", "gene_name": "mfsd2b", "organism": "Zebrafish", "refseq_name": "major facilitator superfamily domain-containing protein 2B", "refseq_ac": [ { "id": "NP_001352893", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352893", "type": "external" } ], "gene_names_uniprotkb": "mfsd2b; si:dkeyp-115a10.3; si:dkeyp-115a10.4", "gene_names_refseq": "mfsd2b; si:dkeyp-115a10.3; si:dkeyp-115a10.4", "protein_names_uniprotkb": "Major facilitator superfamily domain-containing 2B; Major facilitator superfamily domain-containing protein 2B", "protein_names_refseq": "major facilitator superfamily domain containing 2B; major facilitator superfamily domain-containing protein 2B", "tax_id": 7955, "disease": "", "pathway": " (dre:566968); (R-DRE-1660661)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;28878041", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01037803.1, SRR32588730.16080281.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Sep 19, 2018 this sequence version replaced XP_695343.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7R2", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity;GO:0046624 sphingolipid transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051977 lysophospholipid transport;GO:0006869 lipid transport;GO:0055085 transmembrane transport;GO:0008643 carbohydrate transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4J720-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J755-1", "uniprot_id": [ { "id": "A0A0R4J755_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4J755", "type": "external" } ], "mass": 56694.0, "length": 499, "protein_name": "Tyrosine-protein kinase", "gene_name": "hck", "organism": "Zebrafish", "refseq_name": "tyrosine-protein kinase HCK", "refseq_ac": [ { "id": "XP_005174178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174178", "type": "external" } ], "gene_names_uniprotkb": "hck", "gene_names_refseq": "hck", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase HCK", "tax_id": 7955, "disease": "", "pathway": " (dre:101885596); (R-DRE-912631); (R-DRE-9705462)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLR4", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005102 signaling receptor binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4J755-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J8D5-1", "uniprot_id": [ { "id": "A0A0R4J8D5_PIG", "url": "https://www.uniprot.org/uniprot/A0A0R4J8D5", "type": "external" } ], "mass": 20550.0, "length": 180, "protein_name": "Large ribosomal subunit protein uL18m", "gene_name": "MRPL18", "organism": "Pig", "refseq_name": "39S ribosomal protein L18, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_001928391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928391", "type": "external" } ], "gene_names_uniprotkb": "MRPL18", "gene_names_refseq": "MRPL18", "protein_names_uniprotkb": "Large ribosomal subunit protein uL18m; 39S ribosomal protein L18, mitochondrial", "protein_names_refseq": "39S ribosomal protein L18, mitochondrial isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156324); (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "24362565;25271403;25837512;30089917;30723633;32602580;33878294", "class_list": "", "function": "Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RGV8;F1RQV0;F1RX24;F1SB64", "ec_number_list": [], "go_molecular_function": "GO:0008097 5S rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0035928 rRNA import into mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4J8D5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J8N1-1", "uniprot_id": [ { "id": "A0A0R4J8N1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4J8N1", "type": "external" } ], "mass": 59236.0, "length": 539, "protein_name": "CAP-GLY domain-containing linker protein 3", "gene_name": "clip3", "organism": "Zebrafish", "refseq_name": "CAP-Gly domain-containing linker protein 3 isoform X1", "refseq_ac": [ { "id": "XP_005157797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157797", "type": "external" } ], "gene_names_uniprotkb": "clip3", "gene_names_refseq": "clip3", "protein_names_uniprotkb": "CAP-GLY domain-containing linker protein 3", "protein_names_refseq": "CAP-Gly domain-containing linker protein 3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:562450); (R-DRE-5357905)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B410", "ec_number_list": [], "go_molecular_function": "GO:0051010 microtubule plus-end binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005938 cell cortex;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4J8N1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J8U1-1", "uniprot_id": [ { "id": "A0A0R4J8U1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1", "type": "external" } ], "mass": 79945.0, "length": 708, "protein_name": "Tyrosine-protein kinase", "gene_name": "Zap70", "organism": "Rat", "refseq_name": "tyrosine-protein kinase 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"https://www.rhea-db.org/rhea/?query=ec:2.1.1.13", "type": "external" } ], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0004672 protein kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0016020 membrane", "go_biological_process": "GO:0045061 thymic T cell selection;GO:0006955 immune response;GO:0019722 calcium-mediated signaling;GO:0035556 intracellular signal transduction;GO:0050852 T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4J8U1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J8U2-1", "uniprot_id": [ { "id": "A0A0R4J8U2_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0R4J8U2", "type": "external" } ], "mass": 34289.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or2d3b", "organism": "Mouse", "refseq_name": "olfactory receptor 708", "refseq_ac": [ { "id": "NP_001011542", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011542", "type": "external" } ], "gene_names_uniprotkb": "Or2d3b; Olfr1532-ps1; Olfr1532; Olfr709-ps1", "gene_names_refseq": "GA_x6K02T2PBJ9-9297671-9298594; MOR260-6P; MOR260-9P; Olfr1532-ps1; Olfr1532; Olfr708; Or2d3b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "B5 olfactory receptor; olfactory receptor 1532, pseudogene 1; olfactory receptor 708; olfactory receptor MOR260-6P; olfactory receptor MOR260-9P", "tax_id": 10090, "disease": "", "pathway": " (mmu:258173)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4J8U2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R5P9V6-1", "uniprot_id": [ { "id": "A0A0R5P9V6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R5P9V6", "type": "external" } ], "mass": 101001.0, "length": 913, "protein_name": "Carbohydrate-responsive element-binding protein-like; Mlxipl", "gene_name": "mlxipl", "organism": "Zebrafish", "refseq_name": "carbohydrate-responsive element-binding protein", "refseq_ac": [ { "id": "NP_001315623", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315623", "type": "external" } ], "gene_names_uniprotkb": "mlxipl; LOC100535945; Mlxipl", "gene_names_refseq": "chrebp; mlxipl; si:ch1073-189o9.1", "protein_names_uniprotkb": "Carbohydrate-responsive element-binding protein-like; Mlxipl", "protein_names_refseq": "Williams-Beuren syndrome chromosomal region 14 protein homolog; carbohydrate-responsive element-binding protein", "tax_id": 7955, "disease": "", "pathway": " (dre:100535945)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KF713494.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KF713494.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R5P9V6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R8WGG0-1", "uniprot_id": [ { "id": "A0A0R8WGG0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R8WGG0", "type": "external" } ], "mass": 63729.0, "length": 574, "protein_name": "Perforin 19a; Perforin-1.2 precursor", "gene_name": "prf1.2", "organism": "Zebrafish", "refseq_name": "perforin-1.2 precursor", "refseq_ac": [ { "id": "NP_001304689", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304689", "type": "external" } ], "gene_names_uniprotkb": "prf1.2; si:ch211-282e16.3", "gene_names_refseq": "prf1.2; si:ch211-282e16.3", "protein_names_uniprotkb": "Perforin 19a; Perforin-1.2 precursor", "protein_names_refseq": "perforin 19a; perforin-1-like; perforin-1.2 precursor; prf19a", "tax_id": 7955, "disease": "non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); familial hemophagocytic lymphohistiocytosis 2 (Disease Ontology:DOID:0110922); aplastic anemia (Disease Ontology:DOID:12449); Fanconi anemia (Disease Ontology:DOID:13636); colon carcinoma (Disease Ontology:DOID:1520); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); glomerulonephritis (Disease Ontology:DOID:2921); non-Langerhans-cell histiocytosis (Disease Ontology:DOID:4330); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); chronic fatigue syndrome (Disease Ontology:DOID:8544); Crohn's disease (Disease Ontology:DOID:8778); systemic lupus erythematosus (Disease Ontology:DOID:9074); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "23594743;26087843;31348603;35111746", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KP099719.1, DT059709.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476745, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. 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ASTC-R2; Aicr2; AlCR-2; AlCR2; AstC R2; CG13702; Dmel\\CG13702; Dmel_CG13702; Drostar2; anon-WO0170980.154; anon-WO0170980.155; lincRNA.610", "gene_names_refseq": "ASTC-R2; Aicr2; AlCR-2; AlCR2; AstC R2; AstC-R2; AstCR2; CG13702; Dmel\\CG13702; Drostar2; anon-WO0170980.154; anon-WO0170980.155; lincRNA.610", "protein_names_uniprotkb": "Allatostatin C receptor 2, isoform F", "protein_names_refseq": "ASC-receptor; AstC-R2-PF; CG13702-PF; allatostatin C receptor 2, isoform F; allatostatin C receptor2; drosophila allatostatin C receptor 2; somatostatin receptor", "tax_id": 7227, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); opioid abuse (Disease Ontology:DOID:11206); sciatic neuropathy (Disease Ontology:DOID:11446); extrahepatic cholestasis (Disease Ontology:DOID:13619); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); drug psychosis (Disease Ontology:DOID:1742); status epilepticus (Disease Ontology:DOID:1824); post-traumatic stress disorder (Disease Ontology:DOID:2055); brain ischemia (Disease Ontology:DOID:2316); opiate dependence (Disease Ontology:DOID:2559); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); cocaine abuse (Disease Ontology:DOID:809); neonatal abstinence syndrome (Disease Ontology:DOID:9828); obesity (Disease Ontology:DOID:9970); drug dependence (Disease Ontology:DOID:9974); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG13702); (R-DME-391908); (R-DME-418594); (R-DME-5620922)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 27, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004994 somatostatin receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0042277 peptide binding;GO:0008188 neuropeptide receptor activity;GO:0008261 allatostatin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WMT8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S0WNE9-1", "uniprot_id": [ { "id": "A0A0S0WNE9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0S0WNE9", "type": "external" } ], "mass": 35257.0, "length": 307, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG11560", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001303392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303392", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG11560; CG11560; Dmel_CG11560", "gene_names_refseq": "CG11560; Dmel\\CG11560", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG11560-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11560)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0016604 nuclear body", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0S0WNE9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S0WNI0-1", "uniprot_id": [ { "id": "A0A0S0WNI0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0S0WNI0", "type": "external" } ], "mass": 68451.0, "length": 596, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "CG14538", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001303313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303313", "type": "external" } ], "gene_names_uniprotkb": "CG14538; CG46025; CG7196; Dmel\\CG46025; Dmel_CG46025", "gene_names_refseq": "CG14538; CG46025; CG7196; Dmel\\CG46025", "protein_names_uniprotkb": "Uncharacterized protein, isoform D", "protein_names_refseq": "CG46025-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG46025)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WNI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S0WNY8-1", "uniprot_id": [ { "id": "A0A0S0WNY8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0S0WNY8", "type": "external" } ], "mass": 61157.0, "length": 539, "protein_name": "Nicotinic acetylcholine receptor alpha4, isoform H", "gene_name": "nAChRalpha4", "organism": "Fruit fly", "refseq_name": "nicotinic acetylcholine receptor alpha4, isoform H", "refseq_ac": [ { "id": "NP_001303394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303394", "type": "external" } ], "gene_names_uniprotkb": "nAChRalpha4; CG12414; CG17552; Dalpha4; Dmel\\CG12414; Dmel_CG12414; alpha4; anon-WO0138359.1; nAChR-alpha80B; nAChRa4; nAChR; nAcR-alpha-80B; nAcRalpha-4; nAcRalpha-80B; nAcRalpha-80; nAcRaplha-80B; redeye; rye", "gene_names_refseq": "CG12414; CG17552; Dalpha4; Dmel\\CG12414; alpha4; anon-WO0138359.1; nAChR-alpha80B; nAChRa4; nAChRalpha4; nAChR; nAcRalpha-4; nAcRalpha-80B; nAcRalpha-80; nAcRaplha-80B; redeye; rye", "protein_names_uniprotkb": "Nicotinic acetylcholine receptor alpha4, isoform H", "protein_names_refseq": "CG12414-PH; Dalpha4; nAChRalpha4-PH; nicotinic acetylcholine receptor alpha 4; nicotinic acetylcholine receptor alpha 80B; nicotinic acetylcholine receptor alpha4, isoform H; nicotinic acetylcholine receptor alpha4; red-eye; redeye", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); autosomal dominant nocturnal frontal lobe epilepsy 4 (Disease Ontology:DOID:0060685); congenital myasthenic syndrome 4A (Disease Ontology:DOID:0110678); congenital myasthenic syndrome 4C (Disease Ontology:DOID:0110679); lung cancer (Disease Ontology:DOID:1324); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312); congenital myasthenic syndrome (Disease Ontology:DOID:3635); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); lung large cell carcinoma (Disease Ontology:DOID:4556); lung small cell carcinoma (Disease Ontology:DOID:5409); cocaine abuse (Disease Ontology:DOID:809); nasopharynx carcinoma (Disease Ontology:DOID:9261); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG12414); (R-DME-629587); (R-DME-629594); (R-DME-629597); (R-DME-6798695)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0098662 inorganic cation transmembrane transport;GO:0007271 synaptic transmission, cholinergic;GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WNY8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S0WP14-1", "uniprot_id": [ { "id": "A0A0S0WP14_DROME", "url": "https://www.uniprot.org/uniprot/A0A0S0WP14", "type": "external" } ], "mass": 88050.0, "length": 811, "protein_name": "Capricious, isoform E", "gene_name": "caps", "organism": "Fruit fly", "refseq_name": "capricious, isoform E", "refseq_ac": [ { "id": "NP_001303391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303391", "type": "external" } ], "gene_names_uniprotkb": "caps; 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The reference sequence was derived from KR086340.1. On Dec 8, 2015 this sequence version replaced XP_001336749.4., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0S1RUH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S2I7K2-1", "uniprot_id": [ { "id": "A0A0S2I7K2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0S2I7K2", "type": "external" } ], "mass": 116382.0, "length": 1066, "protein_name": "Vinculin", "gene_name": "vclb", "organism": "Zebrafish", "refseq_name": "vinculin b", "refseq_ac": [ { "id": "NP_001304681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304681", "type": "external" } ], "gene_names_uniprotkb": "vclb; vinculin-b", "gene_names_refseq": "vclb; vinculin-b", "protein_names_uniprotkb": "Vinculin; Metavinculin", "protein_names_refseq": "vinculin b", "tax_id": 7955, "disease": "hypertrophic cardiomyopathy 15 (Disease Ontology:DOID:0110321); dilated cardiomyopathy 1W (Disease Ontology:DOID:0110446); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (dre:100334859)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "23594743;23840804;27578788;28767718;30635353;30944477;35417696;35613615;36260739;36314606;36427314;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT862534.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KT862534.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion., [UniProtKB, UniProtKB]; Study show that zebrafish contain two homologous vinculin isoforms, of which the sequence of key functional domains is conserved with several higher vertebrate. Loss of both zygotic vcla and maternal contribution of vcla did not result in notable defects, while the additional loss of zygotic vclb is lethal only after embryonic stages. These data indicate that embryonic development in zebrafish can occur without vinculin. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0005198 structural molecule activity;GO:0008013 beta-catenin binding;GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005925 focal adhesion", "go_biological_process": "GO:0007155 cell adhesion;GO:0007507 heart development;GO:0060977 coronary vasculature morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0S2I7K2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1QT59-1", "uniprot_id": [ { "id": "TMC_DROME", "url": "https://www.uniprot.org/uniprot/A0A0U1QT59", "type": "external" } ], "mass": 227308.0, "length": 2036, "protein_name": "Transmembrane channel-like protein", "gene_name": "Tmc", "organism": "Fruit fly", "refseq_name": "transmembrane channel-like, isoform C", "refseq_ac": [ { "id": "NP_001303362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303362", "type": "external" } ], "gene_names_uniprotkb": "Tmc; CG46121", "gene_names_refseq": "CG14177; CG3280; CG46121; DmTMC; Dmel\\CG46121; TMC; Tic; Tmc-L; Tmc; dTmc; tmc", "protein_names_uniprotkb": "Transmembrane channel-like protein", "protein_names_refseq": "CG46121-PC; Tmc-PC; transmembrane channel-like, isoform C; transmembrane channel-like", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 7 (Disease Ontology:DOID:0110520); autosomal dominant nonsyndromic deafness 36 (Disease Ontology:DOID:0110563); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (dme:Dmel_CG46121)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;27298354;27478019;30853433;31184585;32649914", "class_list": "", "function": "Probable ion channel (PubMed:27478019, PubMed:30853433, PubMed:31184585, PubMed:32649914). Component of mechanosensitive neurons that participates in proprioception, sensing food texture, and directing egg-laying site selection (oviposition) (PubMed:27298354, PubMed:27478019, PubMed:30853433, PubMed:31184585, PubMed:32649914). Component of multi-dendritic neurons of the labellum (md-L) where it is required for sensing the hardness and viscosity of their food, enabling them to behaviorally discriminate their preferred softness and smoothness from harder and stickier food options (PubMed:27478019). Required as part of oviposition site selection process to relay mechanosensory and chemosensory information on the hardness and sweetness of potential egg-laying substrates, thus ensuring females select the most optimal site for their eggs survival (PubMed:31184585, PubMed:32649914). Females determine the softest substrate for their eggs first by making a coarse evaluation of substrate hardness using mechanosensitive channels nan and Piezo in the leg tarsal bristles, followed by a much finer assessment using nan, iav and Tmc mechanosensitive channels on the labellum (PubMed:31184585, PubMed:32649914). This protein is required to sense subtle differences in substrate stiffness (between 0.25% and 0.3% agarose), likely acting in the md-L neurons (PubMed:32649914). Also required in neurons on the labellum, including the md-Ls, and possibly in the brain, to inhibit discrimination of egg-laying substrates of different hardness if the substrate contains sucrose (PubMed:32649914). During oviposition evaluation, activation of sweet neurons by sucrose enhances the activity of the Tmc neurons resulting in females losing their softness preference in favor of egg-laying sites that contain sucrose (PubMed:32649914). Acts in the larvae peripheral sensory neurons, to contribute to proprioception and sensory feedback for normal forward crawling behavior (PubMed:27298354, PubMed:30853433). Required for the normal activity of the proprioceptive sensory dendrites, ddaE which show preferential responses to forward locomotion, and ddaD which show preferential responses to backward locomotion (PubMed:30853433)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "M9NDN5", "ec_number_list": [], "go_molecular_function": "GO:0008381 mechanosensitive monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste;GO:0050974 detection of mechanical stimulus involved in sensory perception;GO:0007635 chemosensory behavior;GO:0019230 proprioception;GO:0019232 perception of rate of movement", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0U1QT59-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RNJ4-1", "uniprot_id": [ { "id": "A0A0U1RNJ4_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0U1RNJ4", "type": "external" } ], "mass": 35272.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or1e31", "organism": "Mouse", "refseq_name": "olfactory receptor 391", "refseq_ac": [ { "id": "NP_001153247", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153247", "type": "external" } ], "gene_names_uniprotkb": "Or1e31; Olfr391-ps; Olfr391", "gene_names_refseq": "MOR135-24; Olfr391-ps1; Olfr391-ps; Olfr391; Or1e31", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "GA_x6K02T2P1NL-3951666-3950698; MOR135-30_i; olfactory receptor 391, pseudogene 1; olfactory receptor 391; olfactory receptor MOR135-24", "tax_id": 10090, "disease": "", "pathway": " (mmu:258236); (R-MMU-381753)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RNJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RNT7-1", "uniprot_id": [ { "id": "A0A0U1RNT7_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0U1RNT7", "type": "external" } ], "mass": 20733.0, "length": 187, "protein_name": "Predicted gene, 30191", "gene_name": "Gm30191", "organism": "Mouse", "refseq_name": "uncharacterized protein C1orf232 homolog isoform 1", "refseq_ac": [ { "id": "NP_001359157", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001359157", "type": "external" } ], "gene_names_uniprotkb": "Gm30191", "gene_names_refseq": "C4H1orf232; 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4.6.1.2", "protein_names_refseq": "guanylate cyclase D precursor; guanylate cyclase D; guanylyl cyclase 2d; guanylyl cyclase D; olfactory guanylyl cyclase GC-D", "tax_id": 10090, "disease": "Leber congenital amaurosis (Disease Ontology:DOID:14791)", "pathway": " (mmu:14918)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14993224;17702944;17724338;20637621;21750661;25428506;27881908;32841674;35820727;9096404", "class_list": "", "function": "Functions as an olfactory receptor activated by urine odorants, uroguanylin and guanylin and as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (PubMed:17702944, PubMed:17724338, PubMed:20637621). Has guanylate cyclase activity upon binding of the ligand (By similarity). Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency (PubMed:17724338, PubMed:20637621). Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (PubMed:20637621)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB]; Mg(2+) binding to GCAPs is critical for setting the actual dynamic range of RetGC regulation by GCAPs at physiological levels of free Ca(2+), [RefSeq, PubMed]; Sensory neurons expressing the atypical olfactory receptor guanylyl cyclase D are required for the acquisition of odor preferences by mice in diverse social contexts., [RefSeq, PubMed]; The S248W mutation contributes to Leber congenital amaurosis 1 by hampering the expression, processing, and/or cellular transport of GUCY2D, rather than its enzymatic properties. 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Results implicate NoBody as a novel component of the mRNA decapping complex and demonstrate potential functionality of a newly discovered microprotein, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 19, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000932 P-body", "go_biological_process": "GO:0006397 mRNA processing;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "A0A0U1RRE5-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRI6-1", "uniprot_id": [ { "id": "CENL3_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0U1RRI6", "type": "external" } ], "mass": 29865.0, "length": 272, "protein_name": "Centromere protein V-like protein 3", "gene_name": "CENPVL3", "organism": "Human", "refseq_name": "centromere protein V-like protein 3", "refseq_ac": [ { "id": "NP_001342205", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001342205", "type": "external" } ], "gene_names_uniprotkb": "CENPVL3; CENPVP3", "gene_names_refseq": "CENPVL3; CENPVP3", "protein_names_uniprotkb": "Centromere protein V-like protein 3; Centromere protein V pseudogene 3", "protein_names_refseq": "centromere protein V-like protein 3", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016846 carbon-sulfur lyase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRI6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRK4-1", "uniprot_id": [ { "id": "LBHD2_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0U1RRK4", "type": "external" } ], "mass": 10701.0, "length": 108, "protein_name": "LBH domain-containing protein 2", "gene_name": "LBHD2", "organism": "Human", "refseq_name": "LBH domain-containing protein 2", "refseq_ac": [ { "id": "NP_001317165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001317165", "type": "external" } ], "gene_names_uniprotkb": "LBHD2", "gene_names_refseq": "LBHD2", "protein_names_uniprotkb": "LBH domain-containing protein 2", "protein_names_refseq": "LBH domain-containing protein 2", "tax_id": 9606, "disease": "", "pathway": " (hsa:107984640)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "35051231", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RRK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRL7-1", "uniprot_id": [ { "id": "MMPOS_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0U1RRL7", "type": "external" } ], "mass": 7680.0, "length": 71, "protein_name": "Protein MMP24OS", "gene_name": "MMP24OS", "organism": "Human", "refseq_name": "protein MMP24OS", "refseq_ac": [ { "id": "NP_001341932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001341932", "type": "external" } ], "gene_names_uniprotkb": "MMP24OS; MMP24-AS1", "gene_names_refseq": "MMP24-AS1; MMP24OS", "protein_names_uniprotkb": "Protein MMP24OS; MMP24 opposite strand", "protein_names_refseq": "MMP24 antisense RNA 1; protein MMP24OS", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "29474001", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RRL7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRN3-1", "uniprot_id": [ { "id": "MISFA_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0U1RRN3", "type": "external" } ], "mass": 6977.0, "length": 59, "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "MISFA", "organism": "Human", "refseq_name": "mitochondrial sheath formation-associated protein", "refseq_ac": [ { "id": "NP_001342499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001342499", "type": "external" } ], "gene_names_uniprotkb": "MISFA; SPTY2D1-AS1; SPTY2D1OS", "gene_names_refseq": "Kastor; MISFA; Polluks; SPTY2D1-AS1; SPTY2D1OS; TSCL1", "protein_names_uniprotkb": "Mitochondrial sheath formation-associated protein; Putative transmembrane protein SPTY2D1OS; SPTY2D1 antisense RNA 1; SPTY2D1 opposite strand", "protein_names_refseq": "SPTY2D1 antisense RNA 1 (non-protein coding); SPTY2D1 opposite strand; mitochondrial sheath formation-associated protein; putative transmembrane protein SPTY2D1OS; testis-specific conserved lncRNA 1", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11237011;35562181", "class_list": "", "function": "Identification of an interactome network between lncRNAs and miRNAs in thyroid cancer reveals SPTY2D1-AS1 as a new tumor suppressor. Publication Status: Online-Only, [RefSeq, PubMed]; Regulates sperm development. May be involved in mitochondrial sheath formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0U1RQZ7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0U1RRN3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRP2-1", "uniprot_id": [ { "id": "A0A0U1RRP2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRP2", "type": "external" } ], "mass": 30000.0, "length": 259, "protein_name": "DCN1-like protein", "gene_name": "Dcun1d2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dcun1d2", "gene_names_refseq": "", "protein_names_uniprotkb": "DCN1-like protein; Defective in cullin neddylation protein 1-like protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8951664)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0097602 cullin family protein binding;GO:0032182 ubiquitin-like protein binding;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:2000436 positive regulation of protein neddylation;GO:2000434 regulation of protein neddylation;GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRP2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRT2-1", "uniprot_id": [ { "id": "A0A0U1RRT2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRT2", "type": "external" } ], "mass": 37879.0, "length": 337, "protein_name": "Solute carrier family 25 member 44", "gene_name": "Slc25a44", "organism": "Rat", "refseq_name": "solute carrier family 25 member 44", "refseq_ac": [ { "id": "NP_001102417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102417", "type": "external" } ], "gene_names_uniprotkb": "Slc25a44", "gene_names_refseq": "RGD1307244; Slc25a44", "protein_names_uniprotkb": "Solute carrier family 25 member 44", "protein_names_refseq": "solute carrier family 25 member 44", "tax_id": 10116, "disease": "", "pathway": " (rno:365841)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial solute transporter which transports branched-chain amino acid (BCAA; valine, leucine and isoleucine) into mitochondria in brown adipose tissue (BAT). BAT is involved in BCAA catabolism and actively utilizes BCAA in the mitochondria for thermogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015658 branched-chain amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane;GO:0016020 membrane", "go_biological_process": "GO:0009083 branched-chain amino acid catabolic process;GO:0006865 amino acid transport;GO:0015803 branched-chain amino acid transport;GO:0120161 regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRT2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRU5-1", "uniprot_id": [ { "id": "A0A0U1RRU5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRU5", "type": "external" } ], "mass": 59797.0, "length": 553, "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1", "gene_name": "Tab1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tab1", "gene_names_refseq": "", "protein_names_uniprotkb": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-168638); (R-RNO-2871837); (R-RNO-445989); (R-RNO-450302); (R-RNO-450321); (R-RNO-5357956); (R-RNO-5607764); (R-RNO-5689880); (R-RNO-9020702); (R-RNO-937042); (R-RNO-937072); (R-RNO-9645460); (R-RNO-975163)", "pathway_count": 13, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Key adapter protein that plays an essential role in JNK and NF-kappa-B activation and proinflammatory cytokines production in response to stimulation with TLRs and cytokines. Mechanistically, associates with the catalytic domain of MAP3K7/TAK1 to trigger MAP3K7/TAK1 autophosphorylation leading to its full activation. Similarly, associates with MAPK14 and triggers its autophosphorylation and subsequent activation. In turn, MAPK14 phosphorylates TAB1 and inhibits MAP3K7/TAK1 activation in a feedback control mechanism. Also plays a role in recruiting MAPK14 to the TAK1 complex for the phosphorylation of the TAB2 and TAB3 regulatory subunits., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019209 kinase activator activity;GO:0060090 molecular adaptor activity;GO:0004722 protein serine/threonine phosphatase activity;GO:0044877 protein-containing complex binding;GO:0048273 mitogen-activated protein kinase p38 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0007165 signal transduction;GO:0043410 positive regulation of MAPK cascade;GO:0030324 lung development;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRU5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRV4-1", "uniprot_id": [ { "id": "A0A0U1RRV4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRV4", "type": "external" } ], "mass": 73593.0, "length": 668, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rnf6", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase RNF6", "refseq_ac": [ { "id": "NP_001100588", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100588", "type": "external" } ], "gene_names_uniprotkb": "Rnf6", "gene_names_refseq": "Rnf6", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF6; ring finger protein (C3H2C3 type) 6", "tax_id": 10116, "disease": "squamous cell carcinoma (Disease Ontology:DOID:1749); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:304271)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32955171", "class_list": "", "function": "Inhibition of RNF6 alleviates traumatic brain injury by suppressing STAT3 signaling in rats., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0050681 nuclear androgen receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030424 axon;GO:0016605 PML body", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0060765 regulation of androgen receptor signaling pathway;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RRV4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRV5-1", "uniprot_id": [ { "id": "A0A0U1RRV5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRV5", "type": "external" } ], "mass": 151166.0, "length": 1349, "protein_name": "Clustered mitochondria protein homolog", "gene_name": "Cluh", "organism": "Rat", "refseq_name": "clustered mitochondria protein homolog", "refseq_ac": [ { "id": "NP_001292142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292142", "type": "external" } ], "gene_names_uniprotkb": "Cluh", "gene_names_refseq": "Cluh; RGD1307222", "protein_names_uniprotkb": "Clustered mitochondria protein homolog", "protein_names_refseq": "clustered mitochondria (cluA/CLU1) homolog; clustered mitochondria homolog; clustered mitochondria protein homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:303300)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0048312 intracellular distribution of mitochondria", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RRV5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRW3-1", "uniprot_id": [ { "id": "A0A0U1RRW3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRW3", "type": "external" } ], "mass": 15837.0, "length": 141, "protein_name": "Active regulator of SIRT1", "gene_name": "Rps19bp1", "organism": "Rat", "refseq_name": "active regulator of SIRT1", "refseq_ac": [ { "id": "NP_001407180", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001407180", "type": "external" } ], "gene_names_uniprotkb": "Rps19bp1", "gene_names_refseq": "RGD1562823; Rps19bp1", "protein_names_uniprotkb": "Active regulator of SIRT1; 40S ribosomal protein S19-binding protein 1", "protein_names_refseq": "active regulator of SIRT1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-3371453)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0032040 small-subunit processome", "go_biological_process": "GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRW3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRY2-1", "uniprot_id": [ { "id": "A0A0U1RRY2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRY2", "type": "external" } ], "mass": 47053.0, "length": 418, "protein_name": "Potassium channel tetramerization domain containing 20", "gene_name": "Kctd20", "organism": "Rat", "refseq_name": "BTB/POZ domain-containing protein KCTD20", "refseq_ac": [ { "id": "NP_001386399", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386399", "type": "external" } ], "gene_names_uniprotkb": "Kctd20", "gene_names_refseq": "Kctd20; RGD1309887", "protein_names_uniprotkb": "Potassium channel tetramerization domain containing 20", "protein_names_refseq": "BTB/POZ domain-containing protein KCTD20; potassium channel tetramerisation domain containing 20", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042327 positive regulation of phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRY2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRY8-1", "uniprot_id": [ { "id": "A0A0U1RRY8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRY8", "type": "external" } ], "mass": 147485.0, "length": 1269, "protein_name": "Regulator of nonsense transcripts 2", "gene_name": "Upf2", "organism": "Rat", "refseq_name": "regulator of nonsense transcripts 2 isoform 1", "refseq_ac": [ { "id": "XP_038951851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038951851", "type": "external" } ], "gene_names_uniprotkb": "Upf2", "gene_names_refseq": "Upf2", "protein_names_uniprotkb": "Regulator of nonsense transcripts 2; Up-frameshift suppressor 2 homolog", "protein_names_refseq": "UPF2 regulator of nonsense transcripts homolog; regulator of nonsense transcripts 2 isoform 1; regulator of nonsense transcripts 2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-975957)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042162 telomeric DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0035145 exon-exon junction complex", "go_biological_process": "GO:0001889 liver development;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031100 animal organ regeneration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRY8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRZ3-1", "uniprot_id": [ { "id": "A0A0U1RRZ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRZ3", "type": "external" } ], "mass": 88420.0, "length": 786, "protein_name": "NF-kappa-B-repressing factor", "gene_name": "Nkrf", "organism": "Rat", "refseq_name": "NF-kappa-B-repressing factor", "refseq_ac": [ { "id": "NP_001389153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001389153", "type": "external" } ], "gene_names_uniprotkb": "Nkrf", "gene_names_refseq": "Nkrf", "protein_names_uniprotkb": "NF-kappa-B-repressing factor", "protein_names_refseq": "NF-kappa-B-repressing factor-like; NF-kappa-B-repressing factor; NF-kappaB repressing factor", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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"CG10611; CG31692; Dmel\\CG31692; FbPase; Fbp; fbp", "protein_names_uniprotkb": "Fructose-1,6-bisphosphatase isozyme 2; 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase; Muscle FBPase", "protein_names_refseq": "CG31692-PF; fbp-PF; fructose-1,6-bisphosphatase, isoform F", "tax_id": 7227, "disease": "fructose-1,6-bisphosphatase deficiency (Disease Ontology:DOID:5204)", "pathway": " (dme:Dmel_CG31692); (R-DME-70263)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12095679;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C6SV43", "ec_number_list": [ { "id": "3.1.3.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.11", "type": "external" } ], "go_molecular_function": "GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030018 Z disc;GO:0070161 anchoring junction", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006000 fructose metabolic process;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0U1RVK6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U2ETD0-1", "uniprot_id": [ { "id": "A0A0U2ETD0_PIG", "url": "https://www.uniprot.org/uniprot/A0A0U2ETD0", "type": "external" } ], "mass": 29237.0, "length": 260, "protein_name": "Emerin", "gene_name": "EMD", "organism": "Pig", "refseq_name": "emerin isoform X2", "refseq_ac": [ { "id": "XP_020936417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936417", "type": "external" } ], "gene_names_uniprotkb": "EMD", "gene_names_refseq": "EMD", "protein_names_uniprotkb": "Emerin", "protein_names_refseq": "emerin isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2980766); (R-SSC-2995383); (R-SSC-4419969); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013408); (R-SSC-9013423); (R-SSC-9609523)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "26743124", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005819 spindle;GO:0032541 cortical endoplasmic reticulum;GO:0005637 nuclear inner membrane;GO:0031616 spindle pole centrosome", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0046827 positive regulation of protein export from nucleus;GO:0071363 cellular response to growth factor stimulus;GO:0048147 negative regulation of fibroblast proliferation;GO:0071763 nuclear membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U2ETD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U2ULT4-1", "uniprot_id": [ { "id": "A0A0U2ULT4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0U2ULT4", "type": "external" } ], "mass": 149399.0, "length": 1367, "protein_name": "Adhesion G protein-coupled receptor A2", "gene_name": "adgra2", "organism": "Zebrafish", "refseq_name": "adhesion G protein-coupled receptor A2 precursor", "refseq_ac": [ { "id": "NP_001305000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000", "type": "external" } ], "gene_names_uniprotkb": "adgra2; gpr124; si:dkey-208c22.2", "gene_names_refseq": "adgra2; gpr124; si:dkey-208c22.2", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor A2; G-protein coupled receptor 124", "protein_names_refseq": "G-protein coupled receptor 124; adhesion G protein-coupled receptor A2 precursor; probable G-protein coupled receptor 124", "tax_id": 7955, "disease": "", "pathway": " (dre:560700)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "23594743;24004948;25715737;26051822;26469318;27189481;35175798;35561544;35649360;36502932;37191285", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT285523.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KT285523.1. On Dec 22, 2015 this sequence version replaced XP_689189.7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; The GPI-anchored MMP inhibitor Reck and the adhesion GPCR Gpr124 are integral components of the Wnt7a/Wnt7b-specific signaling complex required for brain angiogenesis and dorsal root ganglia neurogenesis. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:1990909 Wnt signalosome", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0060070 canonical Wnt signaling pathway;GO:0002040 sprouting angiogenesis;GO:0001944 vasculature development;GO:0022009 central nervous system vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0U2ULT4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U2UZZ5-1", "uniprot_id": [ { "id": "A0A0U2UZZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A0U2UZZ5", "type": "external" } ], "mass": 59627.0, "length": 527, "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "eIF2aK2", "organism": "Hamster", "refseq_name": "interferon-induced, double-stranded RNA-activated protein kinase", "refseq_ac": [ { "id": "NP_001315037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315037", "type": "external" } ], "gene_names_uniprotkb": "eIF2aK2; Eif2ak2", "gene_names_refseq": "Eif2ak2", "protein_names_uniprotkb": "Interferon-induced, double-stranded RNA-activated protein kinase; 2.7.10.2; 2.7.11.1; Eukaryotic translation initiation factor 2-alpha kinase 2; Interferon-inducible RNA-dependent protein kinase; Protein kinase RNA-activated; Tyrosine-protein kinase EIF2AK2", "protein_names_refseq": "interferon-induced, double-stranded RNA-activated protein kinase-like protein; interferon-induced, double-stranded RNA-activated protein kinase", "tax_id": 10029, "disease": "", "pathway": " (cge:100757909)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21945585;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" } ], "go_molecular_function": "GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:1900225 regulation of NLRP3 inflammasome complex assembly;GO:0043066 negative regulation of apoptotic process;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0032722 positive regulation of chemokine production;GO:0045071 negative regulation of viral genome replication", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0U2UZZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U3RBN1-1", "uniprot_id": [ { "id": "A0A0U3RBN1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0U3RBN1", "type": "external" } ], "mass": 59704.0, "length": 545, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "dtx1", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase DTX1", "refseq_ac": [ { "id": "NP_001305881", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305881", "type": "external" } ], "gene_names_uniprotkb": "dtx1", "gene_names_refseq": "dtx1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase DTX1; zmp:0000001121", "tax_id": 7955, "disease": "", "pathway": " (dre:101885597)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23328254;23594743;26714454;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.49704538.1, GFIL01020595.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505378, SAMEA3505380 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Jul 18, 2025 this sequence version replaced NP_001305881.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0030182 neuron differentiation;GO:0016567 protein ubiquitination;GO:0022008 neurogenesis;GO:0010001 glial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0U3RBN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U4AUM5-1", "uniprot_id": [ { "id": "A0A0U4AUM5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0U4AUM5", "type": "external" } ], "mass": 37478.0, "length": 339, "protein_name": "BLT1-like1 protein; Uncharacterized protein LOC100535037", "gene_name": "si:dkey-148a17.5", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100535037", "refseq_ac": [ { "id": "NP_001315622", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315622", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-148a17.5", "gene_names_refseq": "si:dkey-148a17.5", "protein_names_uniprotkb": "BLT1-like1 protein; Uncharacterized protein LOC100535037", "protein_names_refseq": "BLT1-like1 protein; BLT1-like2 protein; uncharacterized protein LOC100535037", "tax_id": 7955, "disease": "", "pathway": " (dre:100535037)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008528 G protein-coupled peptide receptor activity;GO:0004974 leukotriene receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0U4AUM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U4JCX3-1", "uniprot_id": [ { "id": "A0A0U4JCX3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0U4JCX3", "type": "external" } ], "mass": 39459.0, "length": 356, "protein_name": "BLT1-like2 protein; Uncharacterized protein LOC108190685", "gene_name": "si:dkey-148a17.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC108190685", "refseq_ac": [ { "id": "NP_001315635", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315635", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-148a17.6", "gene_names_refseq": "si:dkey-148a17.6", "protein_names_uniprotkb": "BLT1-like2 protein; Uncharacterized protein LOC108190685", "protein_names_refseq": "BLT1-like2 protein; uncharacterized protein LOC108190685", "tax_id": 7955, "disease": "", "pathway": " (dre:108190685)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: KT004423.1 [ECO:0000345] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from KT004423.1. On Jun 28, 2016 this sequence version replaced XP_017212554.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008528 G protein-coupled peptide receptor activity;GO:0004974 leukotriene receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0U4JCX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0X1KG70-1", "uniprot_id": [ { "id": "ORM2B_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0X1KG70", "type": "external" } ], "mass": 35403.0, "length": 313, "protein_name": "Olfactory receptor 4M2", "gene_name": "OR4M2B", "organism": "Human", "refseq_name": "olfactory receptor 4M2", "refseq_ac": [ { "id": "NP_001382225", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382225", "type": "external" } ], "gene_names_uniprotkb": "OR4M2B", "gene_names_refseq": "OR4M2B; OR4M2", "protein_names_uniprotkb": "Olfactory receptor 4M2", "protein_names_refseq": "olfactory receptor 4M2", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0X1KG70-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A125RM76-1", "uniprot_id": [ { "id": "A0A125RM76_CHICK", "url": "https://www.uniprot.org/uniprot/A0A125RM76", "type": "external" } ], "mass": 56357.0, "length": 479, "protein_name": "Interferon-induced protein with tetratricopeptide repeats 5", "gene_name": "IFIT5", "organism": "Chicken", "refseq_name": "interferon-induced protein with tetratricopeptide repeats 5", "refseq_ac": [ { "id": "NP_001307351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307351", "type": "external" } ], "gene_names_uniprotkb": "IFIT5", "gene_names_refseq": "IFIT5", "protein_names_uniprotkb": "Interferon-induced protein with tetratricopeptide repeats 5", "protein_names_refseq": "interferon-induced protein with tetratricopeptide repeats 5", "tax_id": 9031, "disease": "", "pathway": " (gga:423790)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29717152;30271403", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT372799.1, HAEK01038780.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000231.1. On Feb 24, 2016 this sequence version replaced XP_421662.2., [RefSeq]; IFIT5 antagonizes replication of RNA viruses. Publication Status: Online-Only, [RefSeq, PubMed]; This study shows that chickens expressing IFIT5 ameliorate clinical outcome and pathology of highly pathogenic Avian Influenza and velogenic Newcastle Disease viruses Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A125RM76-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A126GUN8-1", "uniprot_id": [ { "id": "A0A126GUN8_DROME", "url": "https://www.uniprot.org/uniprot/A0A126GUN8", "type": "external" } ], "mass": 83489.0, "length": 760, "protein_name": "Kinesin-like protein", "gene_name": "Klp54D", "organism": "Fruit fly", "refseq_name": "Kinesin-like protein at 54D, isoform E", "refseq_ac": [ { "id": "NP_001303355", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303355", "type": "external" } ], "gene_names_uniprotkb": "Klp54D; CG15844; CG43323; DmKlp54D; Dmel\\CG43323; Dmel_CG43323; KIF 12; KIF12; KLP1; KLP54D; Klp1; Klp54D-RA", "gene_names_refseq": "CG15844; CG43323; DmKlp54D; Dmel\\CG43323; KIF 12; KIF12; KLP1; KLP54D; Klp1; Klp54D", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "CG43323-PE; Kinesin-like protein 54D; Kinesin-like protein at 54D, isoform E; Kinesin4A; Klp54D-PE", "tax_id": 7227, "disease": "progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547)", "pathway": " (dme:Dmel_CG43323)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016787 hydrolase activity;GO:0003777 microtubule motor activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005874 microtubule;GO:0005737 cytoplasm;GO:0005871 kinesin complex", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A126GUN8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A126GUP6-1", "uniprot_id": [ { "id": "MP1_DROME", "url": "https://www.uniprot.org/uniprot/A0A126GUP6", "type": "external" } ], "mass": 44939.0, "length": 400, "protein_name": "Melanization protease 1", "gene_name": "MP1", "organism": "Fruit fly", "refseq_name": "melanization protease 1, isoform C", "refseq_ac": [ { "id": "NP_001138002", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138002", "type": "external" } ], "gene_names_uniprotkb": "MP1; CG1102", "gene_names_refseq": "BEST:GH02921; CG1102; Dmel\\CG1102; MP1; SP25; cSP25; proPO-AE", "protein_names_uniprotkb": "Melanization protease 1; 3.4.21.-", "protein_names_refseq": "CG1102-PC; MP1-PC; melanization protease 1, isoform C; melanization protease 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1102)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10731138;12537572;16861233;18854145;22227521", "class_list": "", "function": "Serine protease which plays an essential role in the melanization immune response by acting downstream of sp7 to activate prophenoloxidase (PPO1) (PubMed:16861233). May function in diverse Hayan-dependent PPO1-activating cascades that are negatively controlled by different serpin proteins; Spn27A in the hemolymph and Spn77BA in the trachea (PubMed:16861233, PubMed:18854145). Regulation of melanization and PPO1 activation appears to be largely independent of the Toll signaling pathway (PubMed:16861233)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "B7Z0T0;E8NHA1;Q9Y157", "ec_number_list": [], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding;GO:0017171 serine hydrolase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0009620 response to fungus;GO:0035006 melanization defense response;GO:0160032 Toll receptor ligand protein activation cascade", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A126GUP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A126GUQ2-1", "uniprot_id": [ { "id": "A0A126GUQ2_DROME", "url": "https://www.uniprot.org/uniprot/A0A126GUQ2", "type": "external" } ], "mass": 273878.0, "length": 2326, "protein_name": "Piezo-type mechanosensitive ion channel component", "gene_name": "Pzl", "organism": "Fruit fly", "refseq_name": "Piezo-like", "refseq_ac": [ { "id": "NP_001303493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303493", "type": "external" } ], "gene_names_uniprotkb": "Pzl; CG40188; CG40232; CG40249; CG40328; CG41056; CG41238; CG41369; CG42617; CG42618; CG45783; CR41056; Dmel\\CG45783; Dmel_CG45783; pzl", "gene_names_refseq": "CG40188; CG40232; CG40249; CG40328; CG41056; CG41238; CG41369; CG42617; CG42618; CG45783; CR41056; Dmel\\CG45783; Pzl; pzl", "protein_names_uniprotkb": "Piezo-type mechanosensitive ion channel component", "protein_names_refseq": "CG45783-PE; Piezo-like; Pzl-PE", "tax_id": 7227, "disease": "hereditary lymphedema (Disease Ontology:DOID:0050580); dehydrated hereditary stomatocytosis (Disease 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"synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A126GV06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140B2F4-1", "uniprot_id": [ { "id": "A0A140B2F4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A140B2F4", "type": "external" } ], "mass": 23601.0, "length": 206, "protein_name": "Melanocortin-2 receptor accessory protein 2", "gene_name": "MRAP2", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MRAP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Melanocortin-2 receptor accessory protein 2", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:421836)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0031781 type 3 melanocortin receptor binding;GO:0031782 type 4 melanocortin receptor binding;GO:0070996 type 1 melanocortin receptor binding;GO:0031780 corticotropin hormone receptor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0097009 energy homeostasis;GO:0007631 feeding behavior;GO:0006112 energy reserve metabolic process;GO:1903077 negative regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140B2F4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140JWM8-1", "uniprot_id": [ { "id": "C7162_ARATH", "url": "https://www.uniprot.org/uniprot/A0A140JWM8", "type": "external" } ], "mass": 54323.0, "length": 473, "protein_name": "Cytochrome P450 716A2", "gene_name": "CYP716A2", "organism": "Arabidopsis", "refseq_name": "Cytochrome P450 superfamily protein", "refseq_ac": [ { "id": "NP_198462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_198462", "type": "external" } ], "gene_names_uniprotkb": "CYP716A2; MAB16.9", "gene_names_refseq": "MAB16.8; MAB16_8", "protein_names_uniprotkb": "Cytochrome P450 716A2; 1.14.-.-", "protein_names_refseq": "Cytochrome P450 superfamily protein", "tax_id": 3702, "disease": "", "pathway": " (ath:AT5G36130); (ath:AT5G36140)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10718197;26801524;27862469", "class_list": "", "function": "Possesses triterpene oxidizing activity. Catalyzes the C28 hydroxylation of alpha-amyrin, beta-amyrin, and lupeol, producing uvaol, erythrodiol, and betulin, respectively. Catalyzes the C28 carboxylation of alpha- and beta-amyrin. Possesses 22alpha-hydroxylation activity against alpha- and beta-amaryn., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9LVY3;Q9LVY4", "ec_number_list": [], "go_molecular_function": "GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006722 triterpenoid metabolic process;GO:0016135 saponin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140JWM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.1000000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LFM6-1", "uniprot_id": [ { "id": "MNAR1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LFM6", "type": "external" } ], "mass": 101179.0, "length": 897, "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "minar1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "minar1; si:cabz01029535.1; ubtora", "gene_names_refseq": "", "protein_names_uniprotkb": "Major intrinsically disordered Notch2-binding receptor 1; Membrane integral NOTCH2-associated receptor 1; Ubiquitination and mTOR signaling protein; ubtor", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100331504)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;30080879", "class_list": "", "function": "Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR. Negatively regulates angiogenesis. Negatively regulates cell growth (By similarity). May play a role in neuronal development (PubMed:30080879)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0010977 negative regulation of neuron projection development;GO:0030308 negative regulation of cell growth;GO:0032007 negative regulation of TOR signaling;GO:0031397 negative regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LFM6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LFQ6-1", "uniprot_id": [ { "id": "A0A140LFQ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LFQ6", "type": "external" } ], "mass": 42465.0, "length": 367, "protein_name": "Si:dkey-81n2.2; Uncharacterized protein isoform X1", "gene_name": "si:dkey-81n2.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_009301132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301132", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-81n2.2", "gene_names_refseq": "si:dkey-81n2.2", "protein_names_uniprotkb": "Si:dkey-81n2.2; Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100001804)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B3U0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LFQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LFS0-1", "uniprot_id": [ { "id": "A0A140LFS0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LFS0", "type": "external" } ], "mass": 17279.0, "length": 153, "protein_name": "Si:dkey-241l7.2; Uncharacterized protein LOC569235 precursor", "gene_name": "si:dkey-241l7.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC569235 precursor", "refseq_ac": [ { "id": "NP_001231964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231964", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-241l7.2", "gene_names_refseq": "si:dkey-241l7.2", "protein_names_uniprotkb": "Si:dkey-241l7.2; Uncharacterized protein LOC569235 precursor", "protein_names_refseq": "uncharacterized protein LOC569235 precursor", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); sciatic neuropathy (Disease Ontology:DOID:11446); Sjogren's syndrome (Disease Ontology:DOID:12894); colon cancer (Disease Ontology:DOID:219); acute pancreatitis (Disease Ontology:DOID:2913); cholangiocarcinoma (Disease Ontology:DOID:4947); liver cirrhosis (Disease Ontology:DOID:5082); pneumonia (Disease Ontology:DOID:552); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dre:569235)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16630661;23594743;27189481;31705559", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EV603216.1, EV603736.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000020.1. On Oct 10, 2011 this sequence version replaced XP_003200832.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NZ76", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140LFS0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LFX8-1", "uniprot_id": [ { "id": "A0A140LFX8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LFX8", "type": "external" } ], "mass": 91615.0, "length": 858, "protein_name": "POU domain, class 6, transcription factor 2 isoform X1; Si:ch211-146l10.8", "gene_name": "si:ch211-146l10.8", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-146l10.8 isoform X1", "refseq_ac": [ { "id": "XP_017209484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209484", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-146l10.8", "gene_names_refseq": "si:ch211-146l10.8", "protein_names_uniprotkb": "POU domain, class 6, transcription factor 2 isoform X1; Si:ch211-146l10.8", "protein_names_refseq": "uncharacterized protein si:ch211-146l10.8 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:108179170)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YYA2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LFX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LFZ1-1", "uniprot_id": [ { "id": "A0A140LFZ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LFZ1", "type": "external" } ], "mass": 21001.0, "length": 205, "protein_name": "Histone H1", "gene_name": "si:ch73-368j24.11", "organism": "Zebrafish", "refseq_name": "histone H1-like", "refseq_ac": [ { "id": "XP_005168858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168858", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-368j24.11", "gene_names_refseq": "si:ch73-368j24.11", "protein_names_uniprotkb": "Histone H1", "protein_names_refseq": "histone H1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:562307); (R-DRE-140342)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG38", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LFZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG01-1", "uniprot_id": [ { "id": "A0A140LG01_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG01", "type": "external" } ], "mass": 43261.0, "length": 381, "protein_name": "Myg1 exonuclease; UPF0160 protein MYG1, mitochondrial", "gene_name": "myg1", "organism": "Zebrafish", "refseq_name": "MYG1 exonuclease", "refseq_ac": [ { "id": "NP_001296417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296417", "type": "external" } ], "gene_names_uniprotkb": "myg1; fa14e09; im:6894200; wu:fa14e09; zgc:136866", "gene_names_refseq": "fa14e09; im:6894200; myg1; wu:fa14e09; zgc:136866", "protein_names_uniprotkb": "Myg1 exonuclease; UPF0160 protein MYG1, mitochondrial", "protein_names_refseq": "MYG1 exonuclease; melanocyte proliferating gene 1", "tax_id": 7955, "disease": "", "pathway": " (dre:664752)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01021151.1, SRR26395014.1053490.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 6, 2015 this sequence version replaced XP_009303985.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P777", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140LG01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG17-1", "uniprot_id": [ { "id": "A0A140LG17_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG17", "type": "external" } ], "mass": 23049.0, "length": 207, "protein_name": "TSC22 domain family protein 3", "gene_name": "tsc22d3", "organism": "Zebrafish", "refseq_name": "TSC22 domain family protein 3 isoform 2", "refseq_ac": [ { "id": "NP_001335409", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335409", "type": "external" } ], "gene_names_uniprotkb": "tsc22d3; zgc:64189; zgc:65831; zgc:77028", "gene_names_refseq": "tsc22d3; zgc:64189; zgc:65831; zgc:77028", "protein_names_uniprotkb": "TSC22 domain family protein 3", "protein_names_refseq": "TSC22 domain family protein 3 isoform 2; gilz", "tax_id": 7955, "disease": "", "pathway": " (dre:393541)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "17848559;19874812;20339547;21887364;23594743;23665588;30981015;31249786;31812088;31829580;32030813", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01042100.1, DN899493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505389, SAMEA4476760 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Zebrafish tsc22d3 is a ventralizing gene and plays a role in early embryogenesis, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9N7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A140LG17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG23-1", "uniprot_id": [ { "id": "A0A140LG23_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG23", "type": "external" } ], "mass": 15403.0, "length": 136, "protein_name": "Histone H3", "gene_name": "hist2h3ca1", "organism": "Zebrafish", "refseq_name": "histone 2, H3ca1", "refseq_ac": [ { "id": "NP_001353364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353364", "type": "external" } ], "gene_names_uniprotkb": "hist2h3ca1; cb654; si:dkey-23a13.21", "gene_names_refseq": "cb654; hist2h3ca1; si:dkey-23a13.21", "protein_names_uniprotkb": "Histone H3", "protein_names_refseq": "histone 2, H3ca1", "tax_id": 7955, "disease": "", "pathway": " (dre:368227); (R-DRE-110330); (R-DRE-110331); (R-DRE-201722); (R-DRE-212300); (R-DRE-2299718); (R-DRE-2559580); (R-DRE-2559582); (R-DRE-3214815); (R-DRE-3214841); (R-DRE-3214842); (R-DRE-3214847); (R-DRE-3214858); (R-DRE-427359); (R-DRE-427413); (R-DRE-5250924); (R-DRE-5625886); (R-DRE-5693565); (R-DRE-5693571); (R-DRE-5693607); (R-DRE-68616); (R-DRE-73728); (R-DRE-73772); (R-DRE-8936459); (R-DRE-9018519); (R-DRE-9764725); (R-DRE-983231); (R-DRE-9841922); (R-DRE-9843940); (R-DRE-9843970); (R-DRE-9909649)", "pathway_count": 31, "publication_count": 3, "publication_id_list": "21873635;23594743;30991053", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: SRR32588728.47669717.1, SRR32588718.856149.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Oct 5, 2018 this sequence version replaced XP_009301168.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BAR8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0002088 lens development in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140LG23-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG25-1", "uniprot_id": [ { "id": "A0A140LG25_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG25", "type": "external" } ], "mass": 18266.0, "length": 156, "protein_name": "Si:ch211-277c7.7; Uncharacterized protein LOC100538111", "gene_name": "si:ch211-277c7.7", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100538111", "refseq_ac": [ { "id": "NP_001333134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333134", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-277c7.7", "gene_names_refseq": "si:ch211-277c7.7", "protein_names_uniprotkb": "Si:ch211-277c7.7; Uncharacterized protein LOC100538111", "protein_names_refseq": "uncharacterized protein LOC100538111", "tax_id": 7955, "disease": "", "pathway": " (dre:100538111)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01020320.1, SRR32588721.3059938.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH448435.1 and JBMGRA010000014.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QAT8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LG25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG54-1", "uniprot_id": [ { "id": "A0A140LG54_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG54", "type": "external" } ], "mass": 13594.0, "length": 124, "protein_name": "Histone H2B", "gene_name": "si:dkey-23a13.22", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100536401", "refseq_ac": [ { "id": "NP_001353363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353363", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-23a13.22", "gene_names_refseq": "si:dkey-23a13.22", "protein_names_uniprotkb": "Histone H2B", "protein_names_refseq": "Histone H2B-like; uncharacterized protein LOC100536401", "tax_id": 7955, "disease": "", "pathway": " (dre:100536401); (R-DRE-110330); (R-DRE-110331); (R-DRE-201722); (R-DRE-212300); (R-DRE-2299718); (R-DRE-2559580); (R-DRE-2559582); (R-DRE-3214815); (R-DRE-3214847); (R-DRE-427359); (R-DRE-427413); (R-DRE-5250924); (R-DRE-5625886); (R-DRE-5689880); (R-DRE-5693565); (R-DRE-5693571); (R-DRE-5693607); (R-DRE-68616); (R-DRE-73728); (R-DRE-73772); (R-DRE-8936459); (R-DRE-9018519); (R-DRE-9764725); (R-DRE-9841922); (R-DRE-9843940); (R-DRE-9843970); (R-DRE-9909649)", "pathway_count": 28, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: EH498930.1, CT668065.2 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Oct 5, 2018 this sequence version replaced XP_005172216.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BK11", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140LG54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG86-1", "uniprot_id": [ { "id": "A0A140LG86_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG86", "type": "external" } ], "mass": 36003.0, "length": 307, "protein_name": "Fibrinogen-like protein 1", "gene_name": "fgl1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "fgl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibrinogen-like protein 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100003029)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QGR3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0007596 blood coagulation;GO:0050776 regulation of immune response;GO:0002250 adaptive immune response;GO:0050868 negative regulation of T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LG86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LG91-1", "uniprot_id": [ { "id": "A0A140LG91_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LG91", "type": "external" } ], "mass": 36807.0, "length": 329, "protein_name": "Carcinoembryonic antigen-related cell adhesion molecule 1; Si:ch211-213a13.1", "gene_name": "si:ch211-213a13.1", "organism": "Zebrafish", "refseq_name": "cell adhesion molecule CEACAM1 isoform X1", "refseq_ac": [ { "id": "XP_003201059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201059", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-213a13.1", "gene_names_refseq": "si:ch211-213a13.1", "protein_names_uniprotkb": "Carcinoembryonic antigen-related cell adhesion molecule 1; Si:ch211-213a13.1", "protein_names_refseq": "cell adhesion molecule CEACAM1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100535646)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RTG4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LG91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGC1-1", "uniprot_id": [ { "id": "A0A140LGC1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGC1", "type": "external" } ], "mass": 29613.0, "length": 263, "protein_name": "Protein lifeguard 2", "gene_name": "faim2b", "organism": "Zebrafish", "refseq_name": "Fas apoptotic inhibitory molecule 2b", "refseq_ac": [ { "id": "NP_001373641", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373641", "type": "external" } ], "gene_names_uniprotkb": "faim2b", "gene_names_refseq": "faim2b", "protein_names_uniprotkb": "Protein lifeguard 2; Fas apoptotic inhibitory molecule 2", "protein_names_refseq": "Fas apoptotic inhibitory molecule 2b", "tax_id": 7955, "disease": "", "pathway": " (dre:100006044)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;31399485", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH433299.1, DN858942.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 25, 2025 this sequence version replaced NP_001373641.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PVB6", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0045121 membrane raft;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0097190 apoptotic signaling pathway;GO:0043524 negative regulation of neuron apoptotic process;GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LGC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGD4-1", "uniprot_id": [ { "id": "A0A140LGD4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGD4", "type": "external" } ], "mass": 34475.0, "length": 313, "protein_name": "Aerolysin-like; Hypothetical protein LOC564481", "gene_name": "ntrnl4", "organism": "Zebrafish", "refseq_name": "aerolysin-like", "refseq_ac": [ { "id": "NP_001373496", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373496", "type": "external" } ], "gene_names_uniprotkb": "ntrnl4; LOC564481; loc564481", "gene_names_refseq": "ntrnl4", "protein_names_uniprotkb": "Aerolysin-like; Hypothetical protein LOC564481", "protein_names_refseq": "aerolysin-like", "tax_id": 7955, "disease": "", "pathway": " (dre:564481)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;35151271", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DN859681.1, DN862520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505381, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 29, 2020 this sequence version replaced XP_002662785.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHB6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LGD4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGR1-1", "uniprot_id": [ { "id": "A0A140LGR1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGR1", "type": "external" } ], "mass": 166667.0, "length": 1497, "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 54a isoform 2; Ubiquitin-specific peptidase 54a", "gene_name": "usp54a", "organism": "Zebrafish", "refseq_name": "inactive ubiquitin carboxyl-terminal hydrolase 54a isoform 2", "refseq_ac": [ { "id": "NP_001314804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314804", "type": "external" } ], "gene_names_uniprotkb": "usp54a", "gene_names_refseq": "usp54a", "protein_names_uniprotkb": "Inactive ubiquitin carboxyl-terminal hydrolase 54a isoform 2; Ubiquitin-specific peptidase 54a", "protein_names_refseq": "inactive ubiquitin carboxyl-terminal hydrolase 54a isoform 2", "tax_id": 7955, "disease": "", "pathway": " (dre:563912)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "20040115;23594743;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA4476745, SAMEA4476750 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX649385.8 and BX649277.5. On May 27, 2016 this sequence version replaced XP_005156919.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P960", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "", "go_biological_process": "GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140LGR1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGS0-1", "uniprot_id": [ { "id": "A0A140LGS0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGS0", "type": "external" } ], "mass": 55169.0, "length": 498, "protein_name": "Cystine/glutamate transporter", "gene_name": "slc7a11", "organism": "Zebrafish", "refseq_name": "cystine/glutamate transporter", "refseq_ac": [ { "id": "XP_009289503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289503", "type": "external" } ], "gene_names_uniprotkb": "slc7a11", "gene_names_refseq": "slc7a11", "protein_names_uniprotkb": "Cystine/glutamate transporter; Amino acid transport system xc-; Solute carrier family 7 member 11; xCT", "protein_names_refseq": "cystine/glutamate transporter", "tax_id": 7955, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dre:100151597); (R-DRE-210991); (R-DRE-352230)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B0I3", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0031528 microvillus membrane", "go_biological_process": "GO:0015811 L-cystine transport;GO:0043067 regulation of programmed cell death;GO:0003333 amino acid transmembrane transport;GO:0015813 L-glutamate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGS0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGS2-1", "uniprot_id": [ { "id": "A0A140LGS2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGS2", "type": "external" } ], "mass": 13617.0, "length": 127, "protein_name": "Histone H2A", "gene_name": "si:ch1073-153i20.5", "organism": "Zebrafish", "refseq_name": "si:ch1073-153i20.5", "refseq_ac": [ { "id": "NP_001410749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410749", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-153i20.5", "gene_names_refseq": "si:ch1073-153i20.5", "protein_names_uniprotkb": "Histone H2A", "protein_names_refseq": "si:ch1073-153i20.5", "tax_id": 7955, "disease": "", "pathway": " (dre:103911342); (R-DRE-110330); (R-DRE-110331); (R-DRE-201722); (R-DRE-212300); (R-DRE-2299718); (R-DRE-2559580); (R-DRE-2559582); (R-DRE-3214815); (R-DRE-3214858); (R-DRE-427359); (R-DRE-427413); (R-DRE-5250924); (R-DRE-5625886); (R-DRE-5689603); (R-DRE-5689880); (R-DRE-5689901); (R-DRE-68616); (R-DRE-73728); (R-DRE-73772); (R-DRE-8936459); (R-DRE-9018519); (R-DRE-9764725); (R-DRE-9841922); (R-DRE-9843940); (R-DRE-9843970); (R-DRE-9909649)", "pathway_count": 27, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: EH547624.1, SRR26395014.969482.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 16, 2023 this sequence version replaced XP_009301185.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ATV1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006950 response to stress;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LGS2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGT1-1", "uniprot_id": [ { "id": "A0A140LGT1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGT1", "type": "external" } ], "mass": 23756.0, "length": 201, "protein_name": "Core-binding factor subunit beta", "gene_name": "cbfb", "organism": "Zebrafish", "refseq_name": "core-binding factor subunit beta isoform X1", "refseq_ac": [ { "id": "XP_009291805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291805", "type": "external" } ], "gene_names_uniprotkb": "cbfb; CBFB; unp1266", "gene_names_refseq": "cbfb; unp1266", "protein_names_uniprotkb": "Core-binding factor subunit beta; Polyomavirus enhancer-binding protein 2 beta subunit; SL3-3 enhancer factor 1 subunit beta; SL3/AKV core-binding factor beta subunit", "protein_names_refseq": "core-binding factor subunit beta isoform X1", "tax_id": 7955, "disease": "acute myelomonocytic leukemia (Disease Ontology:DOID:0081082); cleidocranial dysplasia (Disease Ontology:DOID:13994); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:30744); (R-DRE-8877330); (R-DRE-8878166); (R-DRE-8931987); (R-DRE-8934593); (R-DRE-8936459); (R-DRE-8939236); (R-DRE-8939243); (R-DRE-8939245); (R-DRE-8941858); (R-DRE-8951936); (R-DRE-9018519)", "pathway_count": 12, "publication_count": 13, "publication_id_list": "11110689;15378083;16109975;17567667;20336069;23594743;25575784;27471727;27499523;28708822;29343500;31680844;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ARW3", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0030018 Z disc;GO:0016513 core-binding factor complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0060047 heart contraction;GO:0030097 hemopoiesis;GO:0045214 sarcomere organization;GO:0097535 lymphoid lineage cell migration into thymus", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "A0A140LGT1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGT8-1", "uniprot_id": [ { "id": "A0A140LGT8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGT8", "type": "external" } ], "mass": 83087.0, "length": 741, "protein_name": "Fc receptor-like protein 5; Si:cabz01036022.1", "gene_name": "si:cabz01036022.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:cabz01036022.1 isoform X1", "refseq_ac": [ { "id": "XP_017212447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212447", "type": "external" } ], "gene_names_uniprotkb": "si:cabz01036022.1", "gene_names_refseq": "si:cabz01036022.1", "protein_names_uniprotkb": "Fc receptor-like protein 5; Si:cabz01036022.1", "protein_names_refseq": "uncharacterized protein si:cabz01036022.1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100003349); (R-DRE-1236978); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z7S0", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGT9-1", "uniprot_id": [ { "id": "A0A140LGT9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGT9", "type": "external" } ], "mass": 16976.0, "length": 155, "protein_name": "Leukocyte cell-derived chemotaxin-2; Si:ch211-132p1.4", "gene_name": "lect2.3", "organism": "Zebrafish", "refseq_name": "leukocyte cell-derived chemotaxin-2", "refseq_ac": [ { "id": "XP_695533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695533", "type": "external" } ], "gene_names_uniprotkb": "lect2.3; LOC567149", "gene_names_refseq": "lect2.3", "protein_names_uniprotkb": "Leukocyte cell-derived chemotaxin-2; Si:ch211-132p1.4", "protein_names_refseq": "leukocyte cell-derived chemotaxin-2", "tax_id": 7955, "disease": "", "pathway": " (dre:567149)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TBI4", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGU2-1", "uniprot_id": [ { "id": "A0A140LGU2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGU2", "type": "external" } ], "mass": 168776.0, "length": 1502, "protein_name": "ABC-type glutathione-S-conjugate transporter", "gene_name": "abcc6b.2", "organism": "Zebrafish", "refseq_name": "multidrug resistance-associated protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003198194", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198194", "type": "external" } ], "gene_names_uniprotkb": "abcc6b.2", "gene_names_refseq": "abcc6b.2", "protein_names_uniprotkb": "ABC-type glutathione-S-conjugate transporter; 7.6.2.3", "protein_names_refseq": "multidrug resistance-associated protein 1 isoform X1", "tax_id": 7955, "disease": "arterial calcification of infancy (Disease Ontology:DOID:0050644); pseudoxanthoma elasticum (Disease Ontology:DOID:2738); coronary artery disease (Disease Ontology:DOID:3393)", "pathway": " (dre:100002917)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003198194.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RLU3", "ec_number_list": [ { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0015431 ABC-type glutathione S-conjugate transporter activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGU2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGU5-1", "uniprot_id": [ { "id": "A0A140LGU5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGU5", "type": "external" } ], "mass": 44717.0, "length": 403, "protein_name": "Migration and invasion-inhibitory protein", "gene_name": "miip", "organism": "Zebrafish", "refseq_name": "migration and invasion inhibitory protein", "refseq_ac": [ { "id": "NP_001427872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427872", "type": "external" } ], "gene_names_uniprotkb": "miip", "gene_names_refseq": "miip", "protein_names_uniprotkb": "Migration and invasion-inhibitory protein", "protein_names_refseq": "migration and invasion inhibitory protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01023293.1, SRR26395013.1104279.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 4, 2025 this sequence version replaced XP_689123.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UV61", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0030336 negative regulation of cell migration;GO:0010972 negative regulation of G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGU5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGZ3-1", "uniprot_id": [ { "id": "A0A140LGZ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGZ3", "type": "external" } ], "mass": 88605.0, "length": 774, "protein_name": "Kelch-like protein 33; Si:ch211-63p21.8", "gene_name": "si:ch211-63p21.8", "organism": "Zebrafish", "refseq_name": "kelch-like protein 33", "refseq_ac": [ { "id": "XP_005161817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161817", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-63p21.8", "gene_names_refseq": "si:ch211-63p21.8", "protein_names_uniprotkb": "Kelch-like protein 33; Si:ch211-63p21.8", "protein_names_refseq": "kelch-like protein 33", "tax_id": 7955, "disease": "", "pathway": " (dre:101887026)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B8M7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGZ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LGZ4-1", "uniprot_id": [ { "id": "A0A140LGZ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LGZ4", "type": "external" } ], "mass": 18412.0, "length": 156, "protein_name": "A-kinase anchor protein 14; Si:dkeyp-81f3.4", "gene_name": "si:dkeyp-81f3.4", "organism": "Zebrafish", "refseq_name": "A-kinase anchor protein 14", "refseq_ac": [ { "id": "XP_005164735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164735", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-81f3.4", "gene_names_refseq": "si:dkeyp-81f3.4", "protein_names_uniprotkb": "A-kinase anchor protein 14; Si:dkeyp-81f3.4", "protein_names_refseq": "A-kinase anchor protein 14", "tax_id": 7955, "disease": "", "pathway": " (dre:101884343)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BC13", "ec_number_list": [], "go_molecular_function": "GO:0034237 protein kinase A regulatory subunit binding", "go_cellular_component": "GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LGZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH03-1", "uniprot_id": [ { "id": "A0A140LH03_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH03", "type": "external" } ], "mass": 37223.0, "length": 331, "protein_name": "SLAM family member 9; Si:ch1073-220m6.1", "gene_name": "si:ch1073-220m6.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch1073-220m6.1", "refseq_ac": [ { "id": "XP_005168862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168862", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-220m6.1", "gene_names_refseq": "si:ch1073-220m6.1", "protein_names_uniprotkb": "SLAM family member 9; Si:ch1073-220m6.1", "protein_names_refseq": "uncharacterized protein si:ch1073-220m6.1", "tax_id": 7955, "disease": "", "pathway": " (dre:101885667)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG44", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0016020 membrane", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH15-1", "uniprot_id": [ { "id": "A0A140LH15_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH15", "type": "external" } ], "mass": 61770.0, "length": 532, "protein_name": "Si:dkey-88n24.11", "gene_name": "si:dkey-88n24.11", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-88n24.11", "refseq_ac": [ { "id": "XP_683614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683614", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-88n24.11", "gene_names_refseq": "si:dkey-88n24.11", "protein_names_uniprotkb": "Si:dkey-88n24.11", "protein_names_refseq": "uncharacterized protein si:dkey-88n24.11", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TEG0", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005940 septin ring;GO:0015630 microtubule cytoskeleton;GO:0031105 septin complex;GO:0032153 cell division site", "go_biological_process": "GO:0008104 protein localization;GO:0061640 cytoskeleton-dependent cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH15-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH24-1", "uniprot_id": [ { "id": "A0A140LH24_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH24", "type": "external" } ], "mass": 21085.0, "length": 206, "protein_name": "Histone H1", "gene_name": "si:dkey-23a13.17", "organism": "Zebrafish", "refseq_name": "histone H1-like", "refseq_ac": [ { "id": "NP_001373655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373655", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-23a13.17", "gene_names_refseq": "si:dkey-23a13.17", "protein_names_uniprotkb": "Histone H1", "protein_names_refseq": "histone H1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:571135); (R-DRE-140342)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: CK869484.1, CT669353.2 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Sep 2, 2020 this sequence version replaced XP_699791.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7URG1", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LH24-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH27-1", "uniprot_id": [ { "id": "A0A140LH27_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH27", "type": "external" } ], "mass": 188538.0, "length": 1664, "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3", "gene_name": "arap3", "organism": "Zebrafish", "refseq_name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3", "refseq_ac": [ { "id": "XP_687312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687312", "type": "external" } ], "gene_names_uniprotkb": "arap3", "gene_names_refseq": "arap3", "protein_names_uniprotkb": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3", "protein_names_refseq": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3", "tax_id": 7955, "disease": "", "pathway": " (dre:558931); (R-DRE-8980692); (R-DRE-9013148); (R-DRE-9013149); (R-DRE-9013423)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_687312.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TCY9", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0001946 lymphangiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH27-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH29-1", "uniprot_id": [ { "id": "A0A140LH29_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH29", "type": "external" } ], "mass": 28224.0, "length": 246, "protein_name": "NFAT activation molecule 1 isoform X1; Si:ch211-243a20.4", "gene_name": "si:ch211-243a20.4", "organism": "Zebrafish", "refseq_name": "NFAT activation molecule 1 isoform X2", "refseq_ac": [ { "id": "XP_009291929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291929", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-243a20.4", "gene_names_refseq": "si:ch211-243a20.4", "protein_names_uniprotkb": "NFAT activation molecule 1 isoform X1; Si:ch211-243a20.4", "protein_names_refseq": "NFAT activation molecule 1 isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:103909146); (R-DRE-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AKG7", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0016020 membrane", "go_biological_process": "GO:0045577 regulation of B cell differentiation;GO:0001819 positive regulation of cytokine production;GO:0050853 B cell receptor signaling pathway;GO:0050861 positive regulation of B cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH34-1", "uniprot_id": [ { "id": "A0A140LH34_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH34", "type": "external" } ], "mass": 20177.0, "length": 197, "protein_name": "Histone H1", "gene_name": "h1l1", "organism": "Zebrafish", "refseq_name": "histone H1-like", "refseq_ac": [ { "id": "XP_693710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693710", "type": "external" } ], "gene_names_uniprotkb": "h1l1", "gene_names_refseq": "h1l1", "protein_names_uniprotkb": "Histone H1", "protein_names_refseq": "histone H1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:565341); (R-DRE-140342)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_693710.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TF89", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH42-1", "uniprot_id": [ { "id": "A0A140LH42_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH42", "type": "external" } ], "mass": 65216.0, "length": 589, "protein_name": "Rabphilin-3A", "gene_name": "rph3ab", "organism": "Zebrafish", "refseq_name": "rabphilin-3A isoform X3", "refseq_ac": [ { "id": "XP_691832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691832", "type": "external" } ], "gene_names_uniprotkb": "rph3ab", "gene_names_refseq": "rph3ab", "protein_names_uniprotkb": "Rabphilin-3A; Exophilin-1", "protein_names_refseq": "rabphilin-3A isoform X3", "tax_id": 7955, "disease": "", "pathway": " (dre:563377)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_691832.3. COMPLETENESS: full length., [RefSeq]; Plays an essential role in docking and fusion steps of regulated exocytosis. At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release. In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Also plays a role in the exocytosis of arginine vasopressin hormone., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7A7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008289 lipid binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0098850 extrinsic component of synaptic vesicle membrane;GO:0043197 dendritic spine;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0045956 positive regulation of calcium ion-dependent exocytosis;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH60-1", "uniprot_id": [ { "id": "A0A140LH60_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH60", "type": "external" } ], "mass": 34068.0, "length": 315, "protein_name": "Natterin-like; Si:dkeyp-32g11.8", "gene_name": "ntrnl2", "organism": "Zebrafish", "refseq_name": "natterin-like", "refseq_ac": [ { "id": "NP_001373644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373644", "type": "external" } ], "gene_names_uniprotkb": "ntrnl2; si:dkeyp-32g11.8", "gene_names_refseq": "ntrnl2; si:dkeyp-32g11.8", "protein_names_uniprotkb": "Natterin-like; Si:dkeyp-32g11.8", "protein_names_refseq": "natterin-like", "tax_id": 7955, "disease": "", "pathway": " (dre:794319)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;35151271", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CT618537.2, EV756693.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476792, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 31, 2020 this sequence version replaced XP_001332452.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q151", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LH60-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH63-1", "uniprot_id": [ { "id": "A0A140LH63_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH63", "type": "external" } ], "mass": 20664.0, "length": 201, "protein_name": "Histone H1", "gene_name": "si:ch73-368j24.12", "organism": "Zebrafish", "refseq_name": "histone H1-like", "refseq_ac": [ { "id": "NP_001373679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373679", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-368j24.12", "gene_names_refseq": "si:ch73-368j24.12", "protein_names_uniprotkb": "Histone H1", "protein_names_refseq": "histone H1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100537402); (R-DRE-140342)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: CN508714.1, CT625303.2 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RSM5", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LH63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH64-1", "uniprot_id": [ { "id": "A0A140LH64_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH64", "type": "external" } ], "mass": 34469.0, "length": 315, "protein_name": "Aerolysin-like; Hypothetical protein LOC564660", "gene_name": "ntrnl3", "organism": "Zebrafish", "refseq_name": "aerolysin-like", "refseq_ac": [ { "id": "NP_001373566", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373566", "type": "external" } ], "gene_names_uniprotkb": "ntrnl3; LOC564660; loc564660", "gene_names_refseq": "ntrnl3", "protein_names_uniprotkb": "Aerolysin-like; Hypothetical protein LOC564660", "protein_names_refseq": "aerolysin-like", "tax_id": 7955, "disease": "", "pathway": " (dre:564660)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;35151271", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH447437.1, EH435152.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476802 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 28, 2020 this sequence version replaced XP_002662786.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDL5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140LH64-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LH71-1", "uniprot_id": [ { "id": "A0A140LH71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A140LH71", "type": "external" } ], "mass": 87962.0, "length": 765, "protein_name": "Membrane metallo-endopeptidase-like 1", "gene_name": "mmel1", "organism": "Zebrafish", "refseq_name": "membrane metallo-endopeptidase-like 1", "refseq_ac": [ { "id": "XP_017213856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213856", "type": "external" } ], "gene_names_uniprotkb": "mmel1", "gene_names_refseq": "mmel1", "protein_names_uniprotkb": "Membrane metallo-endopeptidase-like 1", "protein_names_refseq": "membrane metallo-endopeptidase-like 1", "tax_id": 7955, "disease": "heart conduction disease (Disease Ontology:DOID:10273)", "pathway": " (dre:560703)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z177", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LH71-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LHF2-1", "uniprot_id": [ { "id": "VSXL2_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LHF2", "type": "external" } ], "mass": 83270.0, "length": 776, "protein_name": "V-set and immunoglobulin domain-containing protein 10-like 2", "gene_name": "Vsig10l2", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Vsig10l2; 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"reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006694 steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LI11-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LI28-1", "uniprot_id": [ { "id": "A0A140LI28_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LI28", "type": "external" } ], "mass": 49639.0, "length": 432, "protein_name": "Family with sequence similarity 81, member B", "gene_name": "Fam81b", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fam81b", "gene_names_refseq": "", "protein_names_uniprotkb": "Family with sequence similarity 81, member B", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LI28-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LI67-1", "uniprot_id": [ { "id": "FRPD2_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LI67", "type": "external" } ], "mass": 152851.0, "length": 1392, "protein_name": "FERM and PDZ domain-containing protein 2", "gene_name": "Frmpd2", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Frmpd2; Gm626", "gene_names_refseq": "", "protein_names_uniprotkb": "FERM and PDZ domain-containing protein 2", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "21750661;29590622;31196628", "class_list": "", "function": "Functions as a scaffold protein and likely plays a role in N-methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic excitatory transmission (PubMed:31196628). May be involved in synapse formation in cone photoreceptor cells (PubMed:29590622). May play a role in the regulation of tight junction formation (By similarity). Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (By similarity). May pNF-kappa-Blay a role in the regulation of NOD2-mediated NF-kappa-B activation in immune response (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005545 1-phosphatidylinositol binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005923 bicellular tight junction;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0070830 bicellular tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140LI67-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LI88-1", "uniprot_id": [ { "id": "ANR31_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LI88", "type": "external" } ], "mass": 206173.0, "length": 1857, "protein_name": "Ankyrin repeat domain-containing protein 31", "gene_name": "Ankrd31", "organism": "Mouse", "refseq_name": "ankyrin repeat domain-containing protein 31", "refseq_ac": [ { "id": "NP_001357857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357857", "type": "external" } ], "gene_names_uniprotkb": "Ankrd31", "gene_names_refseq": "Ankrd31", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 31", "protein_names_refseq": "ankyrin repeat domain-containing protein 31", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "21750661;31000436;31003867;37976262", "class_list": "", "function": "A crystal structure defines a pleckstrin homology (PH) domain in REC114 and its direct intermolecular contacts with ANKRD31. In vivo, ANKRD31 stabilizes REC114 association with the PAR and elsewhere. Our findings inform a model in which ANKRD31 is a scaffold anchoring REC114 and other factors to specific genomic locations, thereby regulating DSB formation., [RefSeq, PubMed]; Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis., [RefSeq, PubMed]; Required for DNA double-strand breaks (DSBs) formation during meiotic recombination (PubMed:31000436, PubMed:31003867). Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation (PubMed:31000436, PubMed:31003867). Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes (PubMed:31000436)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A140LIB3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0007129 homologous chromosome pairing at meiosis;GO:0010780 meiotic DNA double-strand break formation involved in reciprocal meiotic recombination;GO:1903343 positive regulation of meiotic DNA double-strand break formation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140LI88-1", "record_type": "protein", "filter_code": "0000000.0100100.010000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LIA7-1", "uniprot_id": [ { "id": "CT204_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LIA7", "type": "external" } ], "mass": 20635.0, "length": 188, "protein_name": "Uncharacterized protein C20orf204 homolog", "gene_name": "Gm29797", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gm29797", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein C20orf204 homolog", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140LIA7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000100000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LIE7-1", "uniprot_id": [ { "id": "A0A140LIE7_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LIE7", "type": "external" } ], "mass": 35206.0, "length": 315, "protein_name": "Olfactory receptor family 10 subfamily H member 5", "gene_name": "Or10h5", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or10h5; Gm4461; Olfr1564", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily H member 5", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": " (mmu:100043474); (R-MMU-381753)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140LIE7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140LIF8-1", "uniprot_id": [ { "id": "IRGM2_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140LIF8", "type": "external" } ], "mass": 45205.0, "length": 395, "protein_name": "Immunity-related GTPase family M protein 2", "gene_name": "Irgm2", "organism": "Mouse", "refseq_name": "immunity-related GTPase family M protein 2 isoform 1", "refseq_ac": [ { "id": "NP_062313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_062313", "type": "external" } ], "gene_names_uniprotkb": "Irgm2; Iigp2", "gene_names_refseq": "GTPI; Ifggd2; Iigp2; Irgm2", "protein_names_uniprotkb": "Immunity-related GTPase family M protein 2; 3.6.5.-; Interferon-inducible GTPase 2", "protein_names_refseq": "immunity-related GTPase family M protein 2 isoform 1; immunity-related GTPase family M protein 2; interferon inducible GTPase 2; interferon-g induced GTPase; interferon-gamma-inducible GTPase Ifggd2 protein", "tax_id": 10090, "disease": "inflammatory bowel disease 19 (Disease Ontology:DOID:0110890); tuberculosis (Disease Ontology:DOID:399)", "pathway": " (mmu:54396)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10.1101/2023.09.13.557529;17641048;19144319;21750661;22892676;33124745;33124769;34078740;34338548;36629440;9862701", "class_list": "", "function": "Immunity-related GTPase that plays important roles in innate immunity and inflammatory response (PubMed:17641048, PubMed:33124745, PubMed:33124769, PubMed:34078740, PubMed:34338548). Acts as a dynamin-like protein that binds to intracellular membranes and promotes remodeling and trafficking of those membranes (By similarity). Required for clearance of acute protozoan and bacterial infections (PubMed:17641048, PubMed:34078740, PubMed:34338548). Acts by participating to Tgtp1/Irgb6 and Gbp1-mediated parasite killing by promoting their accumulation on the T.gondii parasitophorous vacuole membranes (PubMed:34078740). Also required for prolonged loading of ubiquitin and p62/Sqstm1 to parasitophorous vacuole membranes (PubMed:34078740). Also acts as a key negative regulator of the inflammatory response by inhibiting the non-canonical inflammasome, thereby protecting against Casp11-driven septic shock during endotoxemia (PubMed:33124745, PubMed:33124769)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, UniProtKB, PubMed]; Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii., [RefSeq, PubMed]; P47 GTPases Irgb10 and Iigp2 act together to confer differential susceptibility against murine chlamydial infection., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 9261, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "E9PVI2;Q3TAN6;Q3TNE5;Q3U635;Q9Z1M2", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": 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During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0016020 membrane;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T832-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T834-1", "uniprot_id": [ { "id": "A0A140T834_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T834", "type": "external" } ], "mass": 38190.0, "length": 361, "protein_name": "Kelch domain-containing protein 8B", "gene_name": "KLHDC8B", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KLHDC8B", "gene_names_refseq": "", "protein_names_uniprotkb": "Kelch domain-containing protein 8B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045171 intercellular bridge;GO:0030496 midbody;GO:0110070 cellularization cleavage furrow;GO:0005737 cytoplasm", "go_biological_process": "GO:1902410 mitotic cytokinetic process;GO:0140014 mitotic nuclear division;GO:0098813 nuclear chromosome segregation;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T834-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T837-1", "uniprot_id": [ { "id": "A0A140T837_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T837", "type": "external" } ], "mass": 58437.0, "length": 520, "protein_name": "Amine oxidase", "gene_name": "MAOB", "organism": "Bovine", "refseq_name": "amine oxidase [flavin-containing] B", "refseq_ac": [ { "id": "NP_808813", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_808813", "type": "external" } ], "gene_names_uniprotkb": "MAOB", "gene_names_refseq": "MAOB", "protein_names_uniprotkb": "Amine oxidase; 1.4.3.-", "protein_names_refseq": "MAO-B; amine oxidase [flavin-containing] B; monoamine oxidase type B", "tax_id": 9913, "disease": "", "pathway": " (bta:338445); (R-BTA-141333)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially degrades benzylamine and phenylethylamine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" }, { "id": "1.4.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.21", "type": "external" }, { "id": "1.4.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.4", "type": "external" } ], "go_molecular_function": "GO:0097621 monoamine oxidase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008131 primary methylamine oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006576 biogenic amine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T837-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T838-1", "uniprot_id": [ { "id": "A0A140T838_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T838", "type": "external" } ], "mass": 30702.0, "length": 266, "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IL1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Multifunctional fusion protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-448706); (R-BTA-5620971); (R-BTA-5660668); (R-BTA-9020702); (R-BTA-9960519); (R-BTA-9960525)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0019904 protein domain specific binding;GO:0005125 cytokine activity;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005764 lysosome", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0060252 positive regulation of glial cell proliferation;GO:0033092 positive regulation of immature T cell proliferation in thymus;GO:0001660 fever generation;GO:1903140 regulation of establishment of endothelial barrier", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T838-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T840-1", "uniprot_id": [ { "id": "A0A140T840_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T840", "type": "external" } ], "mass": 11756.0, "length": 107, "protein_name": "Transmembrane protein 213", "gene_name": "TMEM213", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TMEM213", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protein 213", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T840-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T841-1", "uniprot_id": [ { "id": "A0A140T841_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T841", "type": "external" } ], "mass": 22998.0, "length": 214, "protein_name": "Prostamide/prostaglandin F synthase", "gene_name": "PRXL2B", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PRXL2B", "gene_names_refseq": "", "protein_names_uniprotkb": "Prostamide/prostaglandin F synthase; 1.11.1.20; Peroxiredoxin-like 2B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.20", "type": "external" } ], "go_molecular_function": "GO:0047017 prostaglandin F synthase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0043209 myelin sheath", "go_biological_process": "GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T841-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T844-1", "uniprot_id": [ { "id": "A0A140T844_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T844", "type": "external" } ], "mass": 7695.0, "length": 70, "protein_name": "Cytochrome c oxidase subunit 8", "gene_name": "COX8B", "organism": "Bovine", "refseq_name": "cytochrome c oxidase subunit 8B, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001107989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107989", "type": "external" } ], "gene_names_uniprotkb": "COX8B", "gene_names_refseq": "COX8B; IX; VIIIb", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 8; Cytochrome c oxidase polypeptide VIII", "protein_names_refseq": "cytochrome c oxidase polypeptide VIII-heart; cytochrome c oxidase subunit 8-1; cytochrome c oxidase subunit 8B, mitochondrial precursor; cytochrome c oxidase subunit 8B, mitochondrial; cytochrome c oxidase subunit 8H; cytochrome c oxidase subunit VIIIb", "tax_id": 9913, "disease": "", "pathway": " (bta:615757)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16905536", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]; The reduction potentials and the ligation states of heme a3 and CuB are the same for CcO in the O and OH states, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140T844-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T847-1", "uniprot_id": [ { "id": "A0A140T847_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T847", "type": "external" } ], "mass": 40424.0, "length": 362, "protein_name": "Protein Wnt", "gene_name": "WNT16", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "WNT16", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3238698)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0046330 positive regulation of JNK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0030216 keratinocyte differentiation;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T847-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T848-1", "uniprot_id": [ { "id": "A0A140T848_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T848", "type": "external" } ], "mass": 92578.0, "length": 827, "protein_name": "BCAR3 adaptor protein, NSP family member", "gene_name": "BCAR3", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BCAR3", "gene_names_refseq": "", "protein_names_uniprotkb": "BCAR3 adaptor protein, NSP family member", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, 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"uniprot_id": [ { "id": "A0A140T850_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T850", "type": "external" } ], "mass": 52094.0, "length": 474, "protein_name": "Glutathione synthetase", "gene_name": "GSS", "organism": "Bovine", "refseq_name": "glutathione synthetase isoform X2", "refseq_ac": [ { "id": "XP_005214785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214785", "type": "external" } ], "gene_names_uniprotkb": "GSS", "gene_names_refseq": "GSS", "protein_names_uniprotkb": "Glutathione synthetase; 6.3.2.3; GSH-S", "protein_names_refseq": "glutathione synthetase isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-174403)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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], "go_molecular_function": "GO:0004363 glutathione synthase activity;GO:0043295 glutathione binding;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046686 response to cadmium ion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T850-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T851-1", "uniprot_id": [ { "id": "A0A140T851_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T851", "type": "external" } ], "mass": 58919.0, "length": 527, "protein_name": "Vitamin K-dependent protein C", "gene_name": "PROC", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PROC", "gene_names_refseq": "", "protein_names_uniprotkb": "Vitamin K-dependent protein C; 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:281428); (R-BTA-140837); (R-BTA-140875); (R-BTA-159740); (R-BTA-159763); (R-BTA-159782); (R-BTA-202733); (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.21.69", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.69", "type": "external" }, { "id": "3.4.21.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "1.16.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.4", "type": "external" }, { "id": "3.4.21.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.75", "type": "external" }, { "id": "2.3.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.13", "type": "external" }, { "id": "3.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.51", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.4.1.145", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.145", "type": "external" }, { "id": "4.1.1.90", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.90", "type": "external" }, { "id": "3.4.21.112", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.112", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005615 extracellular space", "go_biological_process": "GO:0044537 regulation of circulating fibrinogen levels;GO:0001889 liver development;GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0030195 negative regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T851-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T852-1", "uniprot_id": [ { "id": "A0A140T852_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T852", "type": "external" } ], "mass": 18500.0, "length": 161, "protein_name": "Large ribosomal subunit protein uL30m", "gene_name": "MRPL30", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein uL30m isoform X1", "refseq_ac": [ { "id": "XP_005212407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212407", "type": "external" } ], "gene_names_uniprotkb": "MRPL30", "gene_names_refseq": "MRPL30", "protein_names_uniprotkb": "Large ribosomal subunit protein uL30m; 39S ribosomal protein L30, mitochondrial", "protein_names_refseq": "large ribosomal subunit protein uL30m isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T852-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T853-1", "uniprot_id": [ { "id": "A0A140T853_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T853", "type": "external" } ], "mass": 32477.0, "length": 287, "protein_name": "isopentenyl-diphosphate Delta-isomerase", "gene_name": "IDI1", "organism": "Bovine", "refseq_name": "isopentenyl-diphosphate Delta-isomerase 1", "refseq_ac": [ { "id": "NP_001069127", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069127", "type": "external" } ], "gene_names_uniprotkb": "IDI1", "gene_names_refseq": "IDI1", "protein_names_uniprotkb": "isopentenyl-diphosphate Delta-isomerase; 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The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008188 neuropeptide receptor activity;GO:0015054 gastrin receptor activity;GO:0004951 cholecystokinin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T858-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T859-1", "uniprot_id": [ { "id": "A0A140T859_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T859", "type": "external" } ], "mass": 44225.0, "length": 389, "protein_name": "Cyclin B2", "gene_name": "CCNB2", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CCNB2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclin B2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2500257); (R-BTA-2565942); (R-BTA-2980767); (R-BTA-2995383); (R-BTA-3301854); (R-BTA-69273); (R-BTA-69478)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0040008 regulation of growth;GO:0051301 cell division;GO:0048538 thymus development;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T859-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T861-1", "uniprot_id": [ { "id": "A0A140T861_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T861", "type": "external" } ], "mass": 52382.0, "length": 514, "protein_name": "RNA-binding protein FUS", "gene_name": "FUS", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FUS", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding protein FUS", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-72163); (R-BTA-72203); (R-BTA-9770562)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Also binds its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048255 mRNA stabilization;GO:0051260 protein homooligomerization;GO:1990000 amyloid fibril formation;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T861-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T863-1", "uniprot_id": [ { "id": "A0A140T863_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T863", "type": "external" } ], "mass": 38849.0, "length": 343, "protein_name": "Ring finger protein 113A", "gene_name": "RNF113A", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RNF113A", "gene_names_refseq": "", "protein_names_uniprotkb": "Ring finger protein 113A", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-72163)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005684 U2-type spliceosomal complex;GO:0071005 U2-type precatalytic spliceosome", "go_biological_process": "GO:0070100 negative regulation of chemokine-mediated signaling pathway;GO:0034247 snoRNA splicing;GO:0016567 protein ubiquitination;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T863-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T866-1", "uniprot_id": [ { "id": "A0A140T866_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T866", "type": "external" } ], "mass": 64642.0, "length": 607, "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "PHGDH", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PHGDH", "gene_names_refseq": "", "protein_names_uniprotkb": "D-3-phosphoglycerate dehydrogenase; 1.1.1.95", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-977347)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.95", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.95", "type": "external" }, { "id": "1.1.1.399", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.399", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0004617 phosphoglycerate dehydrogenase activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "", "go_biological_process": "GO:0021782 glial cell development;GO:0021510 spinal cord development;GO:0031175 neuron projection development;GO:0021915 neural tube development;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T866-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T869-1", "uniprot_id": [ { "id": "A0A140T869_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T869", "type": "external" } ], "mass": 13006.0, "length": 117, "protein_name": "Alpha-endosulfine", "gene_name": "ENSA", "organism": "Bovine", "refseq_name": "alpha-endosulfine isoform 2", "refseq_ac": [ { "id": "NP_001300934", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300934", "type": "external" } ], "gene_names_uniprotkb": "ENSA", "gene_names_refseq": "ENSA", "protein_names_uniprotkb": "Alpha-endosulfine", "protein_names_refseq": "ARPP-19e; alpha-endosulfine isoform 2; alpha-endosulfine", "tax_id": 9913, "disease": "", "pathway": " (bta:281142); (R-BTA-2465910)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019870 potassium channel inhibitor activity;GO:0005102 signaling receptor binding;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0051301 cell division;GO:0050796 regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T869-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T870-1", "uniprot_id": [ { "id": "A0A140T870_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T870", "type": "external" } ], "mass": 25380.0, "length": 226, "protein_name": "Homeobox protein prophet of Pit-1", "gene_name": "PROP1", "organism": "Bovine", "refseq_name": "homeobox protein prophet of Pit-1 isoform X1", "refseq_ac": [ { "id": "XP_015327641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327641", "type": "external" } ], "gene_names_uniprotkb": "PROP1", "gene_names_refseq": "PROP1", "protein_names_uniprotkb": "Homeobox protein prophet of Pit-1; Pituitary-specific homeodomain factor", "protein_names_refseq": "homeobox protein prophet of Pit-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0021983 pituitary gland development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T870-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T871-1", "uniprot_id": [ { "id": "A0A140T871_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T871", "type": "external" } ], "mass": 61631.0, "length": 561, "protein_name": "Glutamate dehydrogenase 1, mitochondrial", "gene_name": "GLUD1", "organism": "Bovine", "refseq_name": "glutamate dehydrogenase 1, mitochondrial precursor", "refseq_ac": [ { "id": "NP_872593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_872593", "type": "external" } ], "gene_names_uniprotkb": "GLUD1", "gene_names_refseq": "GDH 1; GDH1; GDH; GLUD1", "protein_names_uniprotkb": "Glutamate dehydrogenase 1, mitochondrial; 1.4.1.3", "protein_names_refseq": "glutamate dehydrogenase 1, mitochondrial precursor; glutamate dehydrogenase 1, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:281785); (R-BTA-2151201); (R-BTA-8964539); (R-BTA-9837999)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "20665690;20675102;27036132;36232607", "class_list": "", "function": "Data show that glutamate dehydrogenase activity in an enzymatic catalyzed reaction by tracing the increasing of oxidation current of NADH., [RefSeq, PubMed]; Data show that heat inactivation of the native GDH enzyme occurred with a rate constant of inactivation of 0.252 min-1., [RefSeq, PubMed]; Near-atomic resolution cryoelectron microscopy structures, at resolutions ranging from 3.2 A to 3.6 A for GDH complexes, is reported., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" }, { "id": "2.7.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.23", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "5.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "2.3.1.168", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.168", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004352 glutamate dehydrogenase (NAD+) activity;GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032024 positive regulation of insulin secretion;GO:0006541 glutamine metabolic process;GO:0006538 glutamate catabolic process;GO:0072350 tricarboxylic acid metabolic process;GO:0006520 amino acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140T871-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T872-1", "uniprot_id": [ { "id": "A0A140T872_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T872", "type": "external" } ], "mass": 21603.0, "length": 187, "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "organism": "Bovine", "refseq_name": "dihydrofolate reductase", "refseq_ac": [ { "id": "NP_001071351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071351", "type": "external" } ], "gene_names_uniprotkb": "DHFR", "gene_names_refseq": "DHFR", "protein_names_uniprotkb": "Dihydrofolate reductase; 1.5.1.3", "protein_names_refseq": "dihydrofolate reductase", "tax_id": 9913, "disease": "", "pathway": " (bta:508809); (R-BTA-196757)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15941833;30078180", "class_list": "", "function": "By using the dual-luciferase reporter system, miR-139 was found to target the 3'-untranslated region of the dihydrofolate reductase (DHFR) gene and regulate its expression., [RefSeq, PubMed]; Hydrogen peroxide down regulates expression in response to angiotensin Ii and underlies endothelial nitric oxide synthase dysfunction., [RefSeq, PubMed]; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.3", "type": "external" } ], "go_molecular_function": "GO:0004146 dihydrofolate reductase activity;GO:0003723 RNA binding;GO:0050661 NADP binding;GO:0033560 folate reductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0006730 one-carbon metabolic process;GO:0046655 folic acid metabolic process;GO:0031427 response to methotrexate;GO:0046452 dihydrofolate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140T872-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T874-1", "uniprot_id": [ { "id": "A0A140T874_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T874", "type": "external" } ], "mass": 53691.0, "length": 490, "protein_name": "2-aminomuconic semialdehyde dehydrogenase", "gene_name": "ALDH8A1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ALDH8A1", "gene_names_refseq": "", "protein_names_uniprotkb": "2-aminomuconic semialdehyde dehydrogenase; 1.2.1.32; Aldehyde dehydrogenase family 8 member A1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5365859)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the NAD-dependent oxidation of 2-aminomuconic semialdehyde of the kynurenine metabolic pathway in L-tryptophan degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.32", "type": "external" } ], "go_molecular_function": "GO:0001758 retinal dehydrogenase activity;GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042573 retinoic acid metabolic process;GO:0042574 retinal metabolic process;GO:0042904 9-cis-retinoic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T874-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T876-1", "uniprot_id": [ { "id": "A0A140T876_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T876", "type": "external" } ], "mass": 33431.0, "length": 291, "protein_name": "Protein RER1", "gene_name": "RER1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RER1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein RER1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033130 acetylcholine receptor binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:1903078 positive regulation of protein localization to plasma membrane;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006621 protein retention in ER lumen;GO:0071340 skeletal muscle acetylcholine-gated channel clustering", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T876-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T877-1", "uniprot_id": [ { "id": "A0A140T877_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T877", "type": "external" } ], "mass": 113084.0, "length": 986, "protein_name": "Transient receptor potential cation channel subfamily C member 4", "gene_name": "TRPC4", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRPC4", "gene_names_refseq": "", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily C member 4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding;GO:0015279 store-operated calcium channel activity;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0005901 caveola;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0014051 gamma-aminobutyric acid secretion;GO:0070509 calcium ion import;GO:0048709 oligodendrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T877-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T878-1", "uniprot_id": [ { "id": "A0A140T878_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T878", "type": "external" } ], "mass": 89943.0, "length": 787, "protein_name": "Signal transducer and activator of transcription", "gene_name": "STAT5B", "organism": "Bovine", "refseq_name": "signal transducer and activator of transcription 5B", "refseq_ac": [ { "id": "NP_777042", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777042", "type": "external" } ], "gene_names_uniprotkb": "STAT5B", "gene_names_refseq": "STAT5B", "protein_names_uniprotkb": "Signal transducer and activator of transcription", "protein_names_refseq": "signal transducer and activator of transcription 5B", "tax_id": 9913, "disease": "", "pathway": " (bta:282376); (R-BTA-1266695); (R-BTA-1433557); (R-BTA-186763); (R-BTA-512988); (R-BTA-8854691); (R-BTA-8983432); (R-BTA-8985947); (R-BTA-9020558); (R-BTA-9020958)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "21435309;24668956;26154111", "class_list": "", "function": "Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation., [UniProtKB, UniProtKB, UniProtKB]; SNPs in JAK2 and STAT5B are associated with mastitis susceptibility in Chinese Holstein cattle, [RefSeq, PubMed]; These results suggested that the SNPs in CD4 and STAT5b may be potential genetic markers for SCS and milk/protein yields selecting and warrant further functional research., [RefSeq, PubMed]; This study suggests that growth hormone inhibits the differentiation of bovine preadipocytes to adipocytes through STAT5b-dependent inhibition of C/EBPalpha and PPARgamma expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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glucocorticoid receptor binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005829 cytosol;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0038162 erythropoietin-mediated signaling pathway;GO:0001779 natural killer cell differentiation;GO:0046543 development of secondary female sexual characteristics;GO:0070669 response to interleukin-2", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140T878-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T879-1", "uniprot_id": [ { "id": "A0A140T879_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T879", "type": "external" } ], "mass": 51668.0, "length": 465, "protein_name": "Chromogranin-A", "gene_name": "CHGA", "organism": 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"go_molecular_function": "GO:0015245 fatty acid transmembrane transporter activity;GO:0042910 xenobiotic transmembrane transporter activity;GO:0015207 adenine transmembrane transporter activity;GO:0015208 guanine transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0035344 hypoxanthine transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T880-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T881-1", "uniprot_id": [ { "id": "A0A140T881_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T881", "type": "external" } ], "mass": 37194.0, "length": 326, "protein_name": "Apolipoprotein E", "gene_name": "APOE", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "APOE", "gene_names_refseq": "", "protein_names_uniprotkb": "Apolipoprotein 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receptor signaling pathway;GO:0008203 cholesterol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T881-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T882-1", "uniprot_id": [ { "id": "A0A140T882_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T882", "type": "external" } ], "mass": 37781.0, "length": 353, "protein_name": "Clathrin binding box of aftiphilin containing 1", "gene_name": "CLBA1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CLBA1", "gene_names_refseq": "", "protein_names_uniprotkb": "Clathrin binding box of aftiphilin containing 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:512628)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030276 clathrin binding", "go_cellular_component": "GO:0032588 trans-Golgi network membrane;GO:0030121 AP-1 adaptor complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T882-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T883-1", "uniprot_id": [ { "id": "A0A140T883_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T883", "type": "external" } ], "mass": 27526.0, "length": 244, "protein_name": "OCIA domain-containing protein 1", "gene_name": "OCIAD1", "organism": "Bovine", "refseq_name": "OCIA domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_005208017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208017", "type": "external" } ], "gene_names_uniprotkb": "OCIAD1", "gene_names_refseq": "Asrij; OCIAD1", "protein_names_uniprotkb": "OCIA domain-containing protein 1", "protein_names_refseq": "OCIA domain-containing protein 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome", "go_biological_process": "GO:2000736 regulation of stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T883-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T885-1", "uniprot_id": [ { "id": "A0A140T885_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T885", "type": "external" } ], "mass": 73417.0, "length": 646, "protein_name": "Secretogranin-1", "gene_name": "CHGB", "organism": "Bovine", "refseq_name": "secretogranin-1 precursor", "refseq_ac": [ { "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349", "type": "external" } ], "gene_names_uniprotkb": "CHGB", "gene_names_refseq": "CHGB", "protein_names_uniprotkb": "Secretogranin-1; Chromogranin-B", "protein_names_refseq": "cgB; chromogranin B (secretogranin 1); secretogranin I; secretogranin-1 precursor; secretogranin-1; sgI", "tax_id": 9913, "disease": "", "pathway": " (bta:281071); (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "14506248;15966749;16140299;18020452", "class_list": "", "function": "CGB may play an important modulatory role in the control of Ca2+ release from the endoplasmic reticulum, [RefSeq, PubMed]; Chromogranin B was found to co-localize with secretogranin II and IP3 receptors in the nucleus, more specifically, in the IP3-sensitive nucleoplasmic Ca2+ store vesicles., [RefSeq, PubMed]; Colocalization of all three inositol 1,4,5-trisphosphate receptor (IP(3)R)isoforms with chromogranin B to the extent that the majority of each IP(3)R isoform-labeling gold particles found in the nucleoplasm, [RefSeq, PubMed]; Determination of the subcellular distribution of chromogranins A and B in chromaffin cells; results suggest that chromogranins are at the center of intracellular Ca(2+) homeostasis in secretory cells, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140T885-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T886-1", "uniprot_id": [ { "id": "A0A140T886_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T886", "type": "external" } ], "mass": 97400.0, "length": 874, "protein_name": "Coatomer subunit gamma", "gene_name": "COPG1", "organism": "Bovine", "refseq_name": "coatomer subunit gamma-1", "refseq_ac": [ { "id": "NP_001032904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032904", "type": "external" } ], "gene_names_uniprotkb": "COPG1", "gene_names_refseq": "COPG1; COPG2; COPG", "protein_names_uniprotkb": "Coatomer subunit gamma", "protein_names_refseq": "coat protein gamma-cop; coatomer protein complex subunit gamma 1; coatomer protein complex, subunit gamma 2; coatomer subunit gamma-1; coatomer subunit gamma; gamma-1-COP; gamma-1-coat protein; gamma-coat protein", "tax_id": 9913, "disease": "", "pathway": " (bta:338055); (R-BTA-6807878); (R-BTA-6811434)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, 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2.1.2.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-196757); (R-BTA-71262)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interconversion of serine and glycine., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004372 glycine hydroxymethyltransferase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005737 cytoplasm;GO:0070013 intracellular organelle lumen", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0046653 tetrahydrofolate metabolic process;GO:0019264 glycine biosynthetic process from serine;GO:0006417 regulation of translation;GO:0051289 protein homotetramerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T896-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T897-1", "uniprot_id": [ { "id": "A0A140T897_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T897", "type": "external" } ], "mass": 69323.0, "length": 607, "protein_name": "Albumin", "gene_name": "ALB", "organism": "Bovine", "refseq_name": "albumin precursor", "refseq_ac": [ { "id": "NP_851335", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851335", "type": "external" } ], "gene_names_uniprotkb": "ALB", "gene_names_refseq": "ALB", "protein_names_uniprotkb": "Albumin", "protein_names_refseq": "BSA; albumin precursor; serum albumin", "tax_id": 9913, "disease": "", "pathway": " (bta:280717); (R-BTA-114608); (R-BTA-159418); (R-BTA-189451); (R-BTA-189483); (R-BTA-2168880); (R-BTA-381426); (R-BTA-8957275); (R-BTA-8964058); (R-BTA-9707564); (R-BTA-9749641); (R-BTA-9757110); (R-BTA-9793528)", "pathway_count": 13, "publication_count": 4, "publication_id_list": "28753530;29126006;29871929;31699587", "class_list": "", "function": "Hese obtained results provide an in-depth understanding of the interaction of the acid azo dye AO10 with serum albumins., [RefSeq, PubMed]; High glucose concentrations inhibited megalin expression and megalin-mediated albumin endocytosis after 48 h of incubation., [RefSeq, PubMed]; The binding constant and quenching constant values suggest that tamoxifen dislodges neratinib from its serum albumin (SA)complex whereas neratinib doesn't affect the interaction between SA and tamoxifen., [RefSeq, PubMed]; The interaction of DRV with bovine serum albumin (BSA), a major carrier protein, has been studied under simulated physiological conditions (pH7.4) by multi-spectroscopic techniques in combination with molecular modeling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005504 fatty acid binding;GO:0015643 toxic substance binding;GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0070062 extracellular exosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0031667 response to nutrient levels;GO:0051902 negative regulation of mitochondrial depolarization;GO:0072732 cellular response to calcium ion starvation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140T897-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T898-1", "uniprot_id": [ { "id": "A0A140T898_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T898", "type": "external" } ], "mass": 25167.0, "length": 224, "protein_name": "Ras-related protein Rab-13", "gene_name": "RAB13", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RAB13", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras-related protein Rab-13; 3.6.5.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8873719); (R-BTA-8876198)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "2.5.1.60", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0055038 recycling endosome membrane;GO:0008021 synaptic vesicle;GO:0030140 trans-Golgi network transport vesicle", "go_biological_process": "GO:0010737 protein kinase A signaling;GO:0015031 protein transport;GO:0006887 exocytosis;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T898-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8A1-1", "uniprot_id": [ { "id": "A0A140T8A1_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8A1", "type": "external" } ], "mass": 22079.0, "length": 209, "protein_name": "Heat shock protein family B (small) member 6", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Heat shock protein family B (small) member 6", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0005212 structural constituent of eye lens;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0045766 positive regulation of angiogenesis;GO:0009408 response to heat;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8A1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8A2-1", "uniprot_id": [ { "id": "A0A140T8A2_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8A2", "type": "external" } ], "mass": 51767.0, "length": 489, "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "DPH2", "organism": "Bovine", "refseq_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "refseq_ac": [ { "id": "NP_001071567", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567", "type": "external" } ], "gene_names_uniprotkb": "DPH2", "gene_names_refseq": "DPH2", "protein_names_uniprotkb": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "protein_names_refseq": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; DPH2 homolog; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2; diphthamide biosynthesis protein 2; diphtheria toxin resistance protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:768224); (R-BTA-5358493)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051536 iron-sulfur cluster binding;GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity", "go_cellular_component": "GO:0120513 2-(3-amino-3-carboxypropyl)histidine synthase complex", "go_biological_process": "GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8A2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8A4-1", "uniprot_id": [ { "id": "A0A140T8A4_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8A4", "type": "external" } ], "mass": 78192.0, "length": 687, "protein_name": "Thimet oligopeptidase", "gene_name": "THOP1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "THOP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Thimet oligopeptidase; 3.4.24.15", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:510889)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"go_molecular_function": "GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0051287 NAD binding;GO:0004450 isocitrate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process;GO:0006103 2-oxoglutarate metabolic process;GO:0006979 response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140T8A5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8A6-1", "uniprot_id": [ { "id": "A0A140T8A6_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8A6", "type": "external" } ], "mass": 30056.0, "length": 273, "protein_name": "Transmembrane ascorbate-dependent reductase CYB561", "gene_name": "CYB561", "organism": "Bovine", "refseq_name": "transmembrane ascorbate-dependent reductase CYB561", "refseq_ac": [ { "id": "NP_777262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777262", "type": "external" } ], "gene_names_uniprotkb": "CYB561", "gene_names_refseq": "CYB561", "protein_names_uniprotkb": "Transmembrane ascorbate-dependent reductase CYB561; Cytochrome b-561; Cytochrome b561", "protein_names_refseq": "chromomembrin B; cytochrome b-561; transmembrane ascorbate-dependent reductase CYB561", "tax_id": 9913, "disease": "", "pathway": " (bta:317663)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12438163;12653566;12768340;16428304;17602662;18501187;21401125", "class_list": "", "function": "A detailed characterization of cyt b561 using electron paramagnetic resonance (EPR) and optical spectroscopy on the wild-type and mutant forms of the cytochrome expressed in insect cells, [RefSeq, PubMed]; Amino-terminal peptide showed that the initial Met residue was acetylated but there was no other posttranslational modification in the amino-terminal region, [RefSeq, PubMed]; Cyb561 from chromaffin cell membranes has high and low potential hemes as demonstrated by electron paramagnetic resonance and circular dichroism., [RefSeq, PubMed]; Importance of the two well-conserved Cys residues near the intravesicular heme center, [RefSeq, PubMed]; The functional and structural roles of the EM3 residues and several adjacent residues (residues 70-85) in the bovine cytochrome, [RefSeq, PubMed]; The pH-induced alteration and the destruction of heme in cytochrome b561 under oxidative conditions may play a significant role in the amplification of oxidative stress in catecholaminergic neurons., [RefSeq, PubMed]; These results indicate that His92 can be considered part of the b(H) heme center, and His110 part of the b(L) heme center, in adrenal cyt b(561)., [RefSeq, PubMed]; Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.1.3", "type": "external" }, { "id": "7.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0140575 transmembrane monodehydroascorbate reductase activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0042584 chromaffin granule membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0140576 ascorbate homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A140T8A6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8A7-1", "uniprot_id": [ { "id": "A0A140T8A7_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8A7", "type": "external" } ], "mass": 41928.0, "length": 376, "protein_name": "Pseudouridylate synthase RPUSD4, mitochondrial", "gene_name": "RPUSD4", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPUSD4", "gene_names_refseq": "", "protein_names_uniprotkb": "Pseudouridylate synthase RPUSD4, mitochondrial; RNA pseudouridylate synthase domain-containing protein 4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. Acts on position 39 in mitochondrial tRNA(Phe). Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.4.99.25", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.25", "type": "external" }, { "id": "5.4.99.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.12", "type": "external" }, { "id": "5.4.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.-", "type": "external" } ], "go_molecular_function": "GO:0000049 tRNA binding;GO:0009982 pseudouridine synthase activity;GO:1990400 mitochondrial ribosomal large subunit rRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005759 mitochondrial matrix;GO:0035770 ribonucleoprotein granule", "go_biological_process": "GO:0031118 rRNA pseudouridine synthesis;GO:1990481 mRNA pseudouridine synthesis;GO:0070131 positive regulation of mitochondrial translation;GO:0070902 mitochondrial tRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8A7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8B4-1", "uniprot_id": [ { "id": "A0A140T8B4_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8B4", "type": "external" } ], "mass": 38960.0, "length": 344, "protein_name": "Zygote arrest 1 like", "gene_name": "ZAR1L", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ZAR1L", "gene_names_refseq": "", "protein_names_uniprotkb": "Zygote arrest 1 like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:616037)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation. Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005737 cytoplasm", "go_biological_process": "GO:0017148 negative regulation of translation;GO:0048477 oogenesis;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8B4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8B9-1", "uniprot_id": [ { "id": "A0A140T8B9_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8B9", "type": "external" } ], "mass": 41031.0, "length": 362, "protein_name": "Prostaglandin F2-alpha receptor", "gene_name": "FP; PTGFR", "organism": "Bovine", "refseq_name": "prostaglandin F2-alpha receptor isoform X1", "refseq_ac": [ { "id": "XP_005204428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204428", "type": "external" } ], "gene_names_uniprotkb": "FP; PTGFR; PTGFR", "gene_names_refseq": "PTGFR", "protein_names_uniprotkb": "Prostaglandin F2-alpha receptor; Prostanoid FP receptor", "protein_names_refseq": "prostaglandin F2-alpha receptor isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-391908); (R-BTA-416476)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004958 prostaglandin F receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8B9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8C0-1", "uniprot_id": [ { "id": "A0A140T8C0_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8C0", "type": "external" } ], "mass": 36241.0, "length": 322, "protein_name": "Interferon regulatory factor", "gene_name": "IRF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IRF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon regulatory factor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:789216)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0043374 CD8-positive, alpha-beta T cell differentiation;GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation;GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8C0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8C3-1", "uniprot_id": [ { "id": "A0A140T8C3_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8C3", "type": "external" } ], "mass": 10442.0, "length": 92, "protein_name": "Selenoprotein K", "gene_name": "SELENOK", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SELENOK", "gene_names_refseq": "", "protein_names_uniprotkb": "Selenoprotein K", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration. Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins. Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation. Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection of cells from ER stress-induced apoptosis. Protects cells from oxidative stress when overexpressed in cardiomyocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0010742 macrophage derived foam cell differentiation;GO:0051223 regulation of protein transport;GO:0006979 response to oxidative stress;GO:2000406 positive regulation of T cell migration;GO:0006816 calcium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8C3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8C5-1", "uniprot_id": [ { "id": "A0A140T8C5_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8C5", "type": "external" } ], "mass": 9861.0, "length": 91, "protein_name": "Uteroglobin", "gene_name": "SCGB1A1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SCGB1A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uteroglobin; Secretoglobin family 1A member 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:767867)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019834 phospholipase A2 inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8C5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8C6-1", "uniprot_id": [ { "id": "A0A140T8C6_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8C6", "type": "external" } ], "mass": 72456.0, "length": 660, "protein_name": "Prosaposin", "gene_name": "PSAP", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PSAP", "gene_names_refseq": "", "protein_names_uniprotkb": "Prosaposin; Proactivator polypeptide", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-375276); (R-BTA-418594); (R-BTA-6798695); (R-BTA-9840310)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling., [UniProtKB, UniProtKB]; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling., [UniProtKB, UniProtKB, UniProtKB]; Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1905573 ganglioside GM1 binding;GO:0002020 protease binding;GO:0005543 phospholipid binding;GO:0042803 protein homodimerization activity;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005764 lysosome;GO:0005770 late endosome;GO:0005576 extracellular region", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0006665 sphingolipid metabolic process;GO:0019216 regulation of lipid metabolic process;GO:0060736 prostate gland growth;GO:0060742 epithelial cell differentiation involved in prostate gland development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8C6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8C8-1", "uniprot_id": [ { "id": "A0A140T8C8_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8C8", "type": "external" } ], "mass": 68039.0, "length": 614, "protein_name": "Thiol proteinase inhibitor", "gene_name": "KNG1", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KNG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Thiol proteinase inhibitor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-140837); (R-BTA-375276); (R-BTA-381426); (R-BTA-416476); (R-BTA-418594); (R-BTA-8957275)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0007162 negative regulation of cell adhesion;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007596 blood coagulation;GO:0042311 vasodilation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8C8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8D2-1", "uniprot_id": [ { "id": "A0A140T8D2_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8D2", "type": "external" } ], "mass": 88562.0, "length": 801, "protein_name": "Integrin beta", "gene_name": "ITGB1", "organism": "Bovine", "refseq_name": "integrin beta-1 isoform X1", "refseq_ac": [ { "id": "XP_005214205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214205", "type": "external" } ], "gene_names_uniprotkb": "ITGB1", "gene_names_refseq": "ITGB1", "protein_names_uniprotkb": "Integrin beta", "protein_names_refseq": "integrin beta-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1566948); (R-BTA-1566977); (R-BTA-198933); (R-BTA-202733); (R-BTA-2129379); (R-BTA-216083); (R-BTA-2173789); (R-BTA-3000170); (R-BTA-3000178); (R-BTA-446343); (R-BTA-8874081); (R-BTA-8875513); (R-BTA-9013404); (R-BTA-9013408); (R-BTA-9013423); (R-BTA-9634597); (R-BTA-9860927)", "pathway_count": 17, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0019901 protein kinase binding;GO:0046872 metal ion binding;GO:0043236 laminin binding;GO:0001968 fibronectin binding", "go_cellular_component": "GO:0035748 myelin sheath abaxonal region;GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0030027 lamellipodium;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0060379 cardiac muscle cell myoblast differentiation;GO:0060912 cardiac cell fate specification;GO:0001701 in utero embryonic development;GO:0007229 integrin-mediated signaling pathway;GO:0008542 visual learning", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8D2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8D3-1", "uniprot_id": [ { "id": "A0A140T8D3_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8D3", "type": "external" } ], "mass": 42806.0, "length": 397, "protein_name": "Ameloblastin", "gene_name": "AMBN", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AMBN", "gene_names_refseq": "", "protein_names_uniprotkb": "Ameloblastin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the mineralization and structural organization of enamel., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0030345 structural constituent of tooth enamel", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007155 cell adhesion;GO:0042475 odontogenesis of dentin-containing tooth;GO:0031214 biomineral tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8D3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8D4-1", "uniprot_id": [ { "id": "A0A140T8D4_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8D4", "type": "external" } ], "mass": 49236.0, "length": 433, "protein_name": "Legumain", "gene_name": "LGMN", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LGMN", "gene_names_refseq": "", "protein_names_uniprotkb": "Legumain; 3.4.22.34; Protease, cysteine 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1679131); (R-BTA-196791); (R-BTA-2132295)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.22.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.34", "type": "external" }, { "id": "3.4.22.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.1", "type": "external" }, { "id": "3.4.22.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.27", "type": "external" }, { "id": "3.4.22.38", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.38", "type": "external" } ], "go_molecular_function": "GO:0061133 endopeptidase activator activity;GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045177 apical part of cell;GO:0048471 perinuclear region of cytoplasm;GO:0005770 late endosome;GO:0043202 lysosomal lumen", "go_biological_process": "GO:2001028 positive regulation of endothelial cell chemotaxis;GO:0007613 memory;GO:0008284 positive regulation of cell population proliferation;GO:0008306 associative learning;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8D4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8D5-1", "uniprot_id": [ { "id": "A0A140T8D5_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A140T8D5", "type": "external" } ], "mass": 9727.0, "length": 85, "protein_name": "Cytochrome c oxidase subunit 7B, mitochondrial", "gene_name": "COX7B", "organism": "Bovine", "refseq_name": "cytochrome c oxidase subunit 7B, mitochondrial precursor", "refseq_ac": [ { "id": "NP_786989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_786989", "type": "external" } ], "gene_names_uniprotkb": "COX7B", "gene_names_refseq": "COX7B; IHQ", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 7B, mitochondrial; Cytochrome c oxidase polypeptide VIIb", "protein_names_refseq": "cytochrome c oxidase polypeptide VIIb; cytochrome c oxidase subunit 7B, mitochondrial precursor; cytochrome c oxidase subunit 7B, mitochondrial; cytochrome c oxidase subunit VIIb", "tax_id": 9913, "disease": "", "pathway": " (bta:100300550)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8D5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8F7-1", "uniprot_id": [ { "id": "A0A140T8F7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A140T8F7", "type": "external" } ], "mass": 26683.0, "length": 239, "protein_name": "Nerve growth factor", "gene_name": "NGF", "organism": "Chicken", "refseq_name": "beta-nerve growth factor precursor", "refseq_ac": [ { "id": "NP_001280037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280037", "type": "external" } ], "gene_names_uniprotkb": "NGF", "gene_names_refseq": "NGFB; NGF; beta-NGF", "protein_names_uniprotkb": "Nerve growth factor", "protein_names_refseq": "beta-nerve growth factor precursor; beta-nerve growth factor; nerve growth factor (beta polypeptide)", "tax_id": 9031, "disease": "", "pathway": " (gga:396466); (R-GGA-1257604); (R-GGA-167060); (R-GGA-170968); (R-GGA-170984); (R-GGA-177504); (R-GGA-187042); (R-GGA-198203); (R-GGA-205017); (R-GGA-205043); (R-GGA-209543); (R-GGA-209560); (R-GGA-209563)", "pathway_count": 13, "publication_count": 4, "publication_id_list": "20018664;22308471;23223289;25846486", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CD217960.1, ERR2286007.72029.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA103992528, SAMEA103992531 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD217960.1, BU337330.1 and BU313448.1. On May 30, 2014 this sequence version replaced XP_003642777.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Data show that endogenous NGF induces DNA replication in a subpopulation of differentiating retinal ganglion cells that express both the neurotrophin receptor p75 and the E2F1 transcription factor, but that lack the retinoblastoma protein., [RefSeq, PubMed]; NGF promotes sensory axon branching through regulation of the actin cytoskeleton using both canonical signaling mechanisms and intra-axonal protein synthesis downstream of PI3K signaling., [RefSeq, PubMed]; Results suggest that NGF differentially affects the phosphorylation of MAP1B within the main axon shaft and the laterally projecting filopodia, [RefSeq, PubMed]; These results reveal a role for NGF in early chicken embryo development., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0030297 transmembrane receptor protein tyrosine kinase activator activity;GO:0005163 nerve growth factor receptor binding;GO:0008191 metalloendopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030424 axon;GO:0030425 dendrite;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0010628 positive regulation of gene expression;GO:0010976 positive regulation of neuron projection development;GO:0051402 neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140T8F7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8F8-1", "uniprot_id": [ { "id": "A0A140T8F8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A140T8F8", "type": "external" } ], "mass": 40905.0, "length": 372, "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase", "gene_name": "RFNG", "organism": "Chicken", "refseq_name": "beta-1,3-N-acetylglucosaminyltransferase radical fringe", "refseq_ac": [ { "id": "NP_990278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990278", "type": "external" } ], "gene_names_uniprotkb": "RFNG", "gene_names_refseq": "RFNG", "protein_names_uniprotkb": "Beta-1,3-N-acetylglucosaminyltransferase; 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "protein_names_refseq": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; beta-1,3-N-acetylglucosaminyltransferase radical fringe", "tax_id": 9031, "disease": "", "pathway": " (gga:395789)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: U91850.1, U82088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000316.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.222", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.222", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0045747 positive regulation of Notch signaling pathway;GO:0007389 pattern specification process;GO:0008593 regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8F8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8G0-1", "uniprot_id": [ { "id": "A0A140T8G0_CHICK", "url": "https://www.uniprot.org/uniprot/A0A140T8G0", "type": "external" } ], "mass": 14212.0, "length": 126, "protein_name": "Liver basic fatty acid binding protein", "gene_name": "LBFABP", "organism": "Chicken", "refseq_name": "fatty acid-binding protein, liver", "refseq_ac": [ { "id": "NP_989965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989965", "type": "external" } ], "gene_names_uniprotkb": "LBFABP", "gene_names_refseq": "FABP10; L-BABP; LB-FABP; LBFABP", "protein_names_uniprotkb": "Liver basic fatty acid binding protein", "protein_names_refseq": "fatty acid-binding protein, liver; liver basic FABP; liver bile acid-binding protein", "tax_id": 9031, "disease": "", "pathway": " (gga:395345)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19540927;24114214", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF380998.1, BG712303.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08016666 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000339.1., [RefSeq]; A high expression level of L-FABP and L-BABP leads to a high lipogenesis rate and, ultimately, to lipid deposition. Publication Status: Online-Only, [RefSeq, PubMed]; Investigation of the gene expression levels of L-FABP and Lb-FABP in relation to the pre-and post-hatching development, diurnal cycle and feeding state in the liver, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005504 fatty acid binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0015908 fatty acid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A140T8G0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8H9-1", "uniprot_id": [ { "id": "A0A140T8H9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A140T8H9", "type": "external" } ], "mass": 55154.0, "length": 469, "protein_name": "Kinetochore protein NUF2", "gene_name": "NUF2", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NUF2", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinetochore protein NUF2; Cell division cycle-associated protein 1; Kinetochore protein Nuf2", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:395135); (R-GGA-141430); (R-GGA-141444); (R-GGA-2467813); (R-GGA-2500257); (R-GGA-5663220); (R-GGA-9648025)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0031262 Ndc80 complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0051383 kinetochore organization;GO:0051301 cell division;GO:0045132 meiotic chromosome segregation;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8H9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8I0-1", "uniprot_id": [ { "id": "A0A140T8I0_CHICK", "url": "https://www.uniprot.org/uniprot/A0A140T8I0", "type": "external" } ], "mass": 14411.0, "length": 131, "protein_name": "Leptin receptor overlapping transcript-like 1", "gene_name": "LEPROTL1", "organism": "Chicken", "refseq_name": "leptin receptor overlapping transcript-like 1", "refseq_ac": [ { "id": "XP_420582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420582", "type": "external" } ], "gene_names_uniprotkb": "LEPROTL1", "gene_names_refseq": "LEPROTL1", "protein_names_uniprotkb": "Leptin receptor overlapping transcript-like 1", "protein_names_refseq": "leptin receptor overlapping transcript-like 1", "tax_id": 9031, "disease": "", "pathway": " (gga:422625)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005768 endosome;GO:0016020 membrane", "go_biological_process": "GO:0060400 negative regulation of growth hormone receptor signaling pathway;GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8I0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140T8I4-1", "uniprot_id": [ { "id": "A0A140T8I4_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A140T8I4", "type": "external" } ], "mass": 26684.0, "length": 237, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Cdc34b", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cdc34b; 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The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1NBV5", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0031788 motilin receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140TAJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140TAJ8-1", "uniprot_id": [ { "id": "A0A140TAJ8_PIG", "url": "https://www.uniprot.org/uniprot/A0A140TAJ8", "type": "external" } ], "mass": 40678.0, "length": 380, "protein_name": "Protein c-Fos", "gene_name": "FOS", "organism": "Pig", "refseq_name": "protein c-Fos", "refseq_ac": [ { "id": "NP_001116585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116585", "type": "external" } ], "gene_names_uniprotkb": "FOS", "gene_names_refseq": "FOS; c-fos", "protein_names_uniprotkb": "Protein c-Fos; Cellular oncogene fos", "protein_names_refseq": "cellular oncogene fos; protein c-Fos; proto-oncogene c-Fos; proto-oncogene protein c-fos; transcription factor AP-1 subunit c-Fos; v-fos FBJ murine osteosarcoma viral oncogene homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144486); (R-SSC-2559580); (R-SSC-2871796); (R-SSC-450341); (R-SSC-9018519)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "23164930", "class_list": "", "function": "Suggest that catecholaminergic and 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"reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0032993 protein-DNA complex;GO:0035976 transcription factor AP-1 complex", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0007179 transforming growth factor beta 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"Pig", "refseq_name": "39S ribosomal protein L3, mitochondrial", "refseq_ac": [ { "id": "XP_001925073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925073", "type": "external" } ], "gene_names_uniprotkb": "MRPL3", "gene_names_refseq": "MRPL3", "protein_names_uniprotkb": "Large ribosomal subunit protein uL3m; 39S ribosomal protein L3, mitochondrial", "protein_names_refseq": "39S ribosomal protein L3, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156322); (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "24362565;30089917;32602580;33878294;37141370", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A140UHW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHW6-1", "uniprot_id": [ { "id": "A0A140UHW6_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHW6", "type": "external" } ], "mass": 72298.0, "length": 663, "protein_name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "gene_name": "Trmt1", "organism": "Rat", "refseq_name": "tRNA (guanine(26)-N(2))-dimethyltransferase isoform X2", "refseq_ac": [ { "id": "XP_006255298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006255298", "type": "external" } ], "gene_names_uniprotkb": "Trmt1", "gene_names_refseq": "RGD1305992; Trmt1", "protein_names_uniprotkb": "tRNA (guanine(26)-N(2))-dimethyltransferase; 2.1.1.216", "protein_names_refseq": "tRNA (guanine(26)-N(2))-dimethyltransferase isoform X2", "tax_id": 10116, "disease": "autosomal recessive intellectual developmental disorder 68 (Disease Ontology:DOID:0081229)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.216", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.216", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000049 tRNA binding;GO:0160104 tRNA (guanine(26)-N2)-dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0002940 tRNA N2-guanine methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140UHW6-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHW9-1", "uniprot_id": [ { "id": "A0A140UHW9_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHW9", "type": "external" } ], "mass": 164320.0, "length": 1423, "protein_name": "Forkhead associated phosphopeptide binding domain 1", "gene_name": "Fhad1", "organism": "Rat", "refseq_name": "forkhead-associated domain-containing protein 1", "refseq_ac": [ { "id": "NP_001037733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001037733", "type": "external" } ], "gene_names_uniprotkb": "Fhad1", "gene_names_refseq": "Fhad1; RGD1563444", "protein_names_uniprotkb": "Forkhead associated phosphopeptide binding domain 1", "protein_names_refseq": "forkhead-associated (FHA) phosphopeptide binding domain 1; forkhead-associated domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036126 sperm flagellum", "go_biological_process": "GO:0007283 spermatogenesis;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140UHW9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHX1-1", "uniprot_id": [ { "id": "A0A140UHX1_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHX1", "type": "external" } ], "mass": 71300.0, "length": 648, "protein_name": "Leucine-rich repeat and WD repeat-containing protein 1", "gene_name": "Lrwd1", "organism": "Rat", "refseq_name": "leucine-rich repeat and WD repeat-containing protein 1", "refseq_ac": [ { "id": "NP_001014003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014003", "type": "external" } ], "gene_names_uniprotkb": "Lrwd1", "gene_names_refseq": "Lrwd1", "protein_names_uniprotkb": "Leucine-rich repeat and WD repeat-containing protein 1; Origin recognition complex-associated protein", "protein_names_refseq": "leucine-rich repeat and WD repeat-containing protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "37551430", "class_list": "", "function": "Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008327 methyl-CpG binding;GO:0061628 histone H3K27me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0006260 DNA replication;GO:0006325 chromatin organization;GO:0071169 establishment of protein localization to chromatin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140UHX1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHX3-1", "uniprot_id": [ { "id": "A0A140UHX3_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHX3", "type": "external" } ], "mass": 168778.0, "length": 1497, "protein_name": "Condensin-2 complex subunit D3", "gene_name": "Ncapd3", "organism": "Rat", "refseq_name": "condensin-2 complex subunit D3 isoform X1", "refseq_ac": [ { "id": "XP_006242797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006242797", "type": "external" } ], "gene_names_uniprotkb": "Ncapd3", "gene_names_refseq": "Ncapd3", "protein_names_uniprotkb": "Condensin-2 complex subunit D3", "protein_names_refseq": "condensin-2 complex subunit D3 isoform X1", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 22 (Disease Ontology:DOID:0051033)", "pathway": " (R-RNO-2299718)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding;GO:0140117 histone H4K20me1 reader activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0000793 condensed chromosome;GO:0000776 kinetochore;GO:0000796 condensin complex", "go_biological_process": "GO:1905820 positive regulation of chromosome separation;GO:0051984 positive regulation of chromosome segregation;GO:0051307 meiotic chromosome separation;GO:0051301 cell division;GO:0007076 mitotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140UHX3-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHX4-1", "uniprot_id": [ { "id": "A0A140UHX4_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHX4", "type": "external" } ], "mass": 63055.0, "length": 567, "protein_name": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "gene_name": "Prkag2", "organism": "Rat", "refseq_name": "5'-AMP-activated protein kinase subunit gamma-2 isoform X5", "refseq_ac": [ { "id": "XP_006236013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006236013", "type": "external" } ], "gene_names_uniprotkb": "Prkag2", "gene_names_refseq": "Prkag2", "protein_names_uniprotkb": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "protein_names_refseq": "5'-AMP-activated protein kinase subunit gamma-2 isoform X5", "tax_id": 10116, "disease": "lethal congenital glycogen storage disease of heart (Disease Ontology:DOID:0090101); hypertrophic cardiomyopathy 6 (Disease Ontology:DOID:0110312); neurodegenerative disease (Disease Ontology:DOID:1289); glycogen storage disease (Disease Ontology:DOID:2747); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384)", "pathway": " (R-RNO-1632852); (R-RNO-163680); (R-RNO-200425); (R-RNO-380972); (R-RNO-5628897); (R-RNO-6804756); (R-RNO-9931269)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0008603 cAMP-dependent protein kinase regulator activity;GO:0008607 phosphorylase kinase regulator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0031588 nucleotide-activated protein kinase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006110 regulation of glycolytic process;GO:0035556 intracellular signal transduction;GO:0005977 glycogen metabolic process;GO:0006633 fatty acid biosynthetic process;GO:0019217 regulation of fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140UHX4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHX9-1", "uniprot_id": [ { "id": "A0A140UHX9_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHX9", "type": "external" } ], "mass": 55597.0, "length": 480, "protein_name": "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated", "gene_name": "Ccz1", "organism": "Rat", "refseq_name": "vacuolar fusion protein CCZ1 homolog isoform 1", "refseq_ac": [ { "id": "NP_001381209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381209", "type": "external" } ], "gene_names_uniprotkb": "Ccz1; Ccz1b", "gene_names_refseq": "Ccz1b; Ccz1; RGD1306410", "protein_names_uniprotkb": "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated", "protein_names_refseq": "CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated; CCZ1 homolog, vacuolar protein trafficking and biogenesis associated B; CCZ1 vacuolar protein trafficking and biogenesis associated homolog; vacuolar fusion protein CCZ1 homolog isoform 1; vacuolar fusion protein CCZ1 homolog", "tax_id": 10116, "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (R-RNO-8876198)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0035658 Mon1-Ccz1 complex", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140UHX9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A142EGP8-1", "uniprot_id": [ { "id": "A0A142EGP8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A142EGP8", "type": "external" } ], "mass": 54536.0, "length": 505, "protein_name": "Monocarboxylate transporter 10", "gene_name": "SLC16A10", "organism": "Chicken", "refseq_name": "monocarboxylate transporter 10", "refseq_ac": [ { "id": "NP_001308665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308665", "type": "external" } ], "gene_names_uniprotkb": "SLC16A10", "gene_names_refseq": "SLC16A10", "protein_names_uniprotkb": "Monocarboxylate transporter 10; Solute carrier family 16 member 10", "protein_names_refseq": "monocarboxylate transporter 10; solute carrier family 16 (aromatic amino acid transporter), member 10; solute carrier family 16, member 10 (aromatic amino acid transporter)", "tax_id": 9031, "disease": "", "pathway": " (gga:421753); (R-GGA-352230)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT876068.1, SRR13267659.198121.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000065.1. On Mar 30, 2016 this sequence version replaced XP_419783.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015196 L-tryptophan transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0015349 thyroid hormone transmembrane transporter activity;GO:0005302 L-tyrosine transmembrane transporter activity;GO:0015192 L-phenylalanine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0030054 cell junction;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "GO:0006590 thyroid hormone generation;GO:0070460 thyroid-stimulating hormone secretion;GO:0070327 thyroid hormone transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A142EGP8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A142EGP9-1", "uniprot_id": [ { "id": "A0A142EGP9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A142EGP9", "type": "external" } ], "mass": 55139.0, "length": 509, "protein_name": "Monocarboxylate transporter 10", "gene_name": "SLC16A2", "organism": "Chicken", "refseq_name": "monocarboxylate transporter 8", "refseq_ac": [ { "id": "NP_001308666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308666", "type": "external" } ], "gene_names_uniprotkb": "SLC16A2", "gene_names_refseq": "SLC16A2", "protein_names_uniprotkb": "Monocarboxylate transporter 10; Solute carrier family 16 member 10", "protein_names_refseq": "monocarboxylate transporter 8; solute carrier family 16, member 2 (monocarboxylic acid transporter 8); solute carrier family 16, member 2 (thyroid hormone transporter)", "tax_id": 9031, "disease": "", "pathway": " (gga:428716); (R-GGA-879518)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01095239.1, KT876069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Mar 30, 2016 this sequence version replaced XP_426274.2., [RefSeq]; Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015196 L-tryptophan transmembrane transporter activity;GO:0042802 identical protein binding;GO:0015349 thyroid hormone transmembrane transporter activity;GO:0005302 L-tyrosine transmembrane transporter activity;GO:0015192 L-phenylalanine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006520 amino acid metabolic process;GO:0042403 thyroid hormone metabolic process;GO:2000178 negative regulation of neural precursor cell proliferation;GO:0070327 thyroid hormone transport;GO:0089718 amino acid import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A142EGP9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A142FJB3-1", "uniprot_id": [ { "id": "A0A142FJB3_PIG", "url": "https://www.uniprot.org/uniprot/A0A142FJB3", "type": "external" } ], "mass": 20200.0, "length": 180, "protein_name": "Interleukin-17B", "gene_name": "IL17B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IL17B", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-17B; Neuronal interleukin-17-related factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:1900017 positive regulation of cytokine production involved in inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A142FJB3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A142J9E8-1", "uniprot_id": [ { "id": "A0A142J9E8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A142J9E8", "type": "external" } ], "mass": 128679.0, "length": 1151, "protein_name": "Voltage-gated delayed rectifier potassium channel KCNH4", "gene_name": "kcnh4a", "organism": "Zebrafish", "refseq_name": "potassium voltage-gated channel subfamily H member 4a", "refseq_ac": [ { "id": "NP_001309362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309362", "type": "external" } ], "gene_names_uniprotkb": "kcnh4a; Kcnh4a; kcnh4; si:ch211-210g13.3", "gene_names_refseq": "kcnh4a; kcnh4; si:ch211-210g13.3", "protein_names_uniprotkb": "Voltage-gated delayed rectifier potassium channel KCNH4; Brain-specific eag-like channel 2; Ether-a-go-go-like potassium channel 1; Potassium voltage-gated channel subfamily H member 4; Voltage-gated potassium channel subunit Kv12.3", "protein_names_refseq": "potassium voltage-gated channel subfamily H member 4a; potassium voltage-gated channel, subfamily H (eag-related), member 4; voltage-gated potassium channel KCNH4a", "tax_id": 7955, "disease": "", "pathway": " (dre:100148126)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23594743;26426478;27189481;32533080;36805134", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KR733682.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN18715637 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KR733682.1. On Apr 12, 2016 this sequence version replaced XP_001920653.3., [RefSeq]; Pore-forming (alpha) subunit of a voltage-gated delayed rectifier. Activates at more negative voltages, exhibits fast prepulse-independent activation kinetics and deactivates much more slowly, but shows no inactivation., [UniProtKB, UniProtKB]; The mutant kcnh4a (kcnh4a(-/-)) larvae showed reduced sleep time and consolidation, specifically during the night, suggesting that Kcnh4a regulates sleep. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A286YA05;A0A8M1P8D7", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005249 voltage-gated potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A142J9E8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A160F7C1-1", "uniprot_id": [ { "id": "A0A160F7C1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A160F7C1", "type": "external" } ], "mass": 47763.0, "length": 425, "protein_name": "Corticosteroid binding globulin; Serpin family A member 1", "gene_name": "SPIA4", "organism": "Chicken", "refseq_name": "serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 precursor", "refseq_ac": [ { "id": "NP_001264421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264421", "type": "external" } ], "gene_names_uniprotkb": "SPIA4", "gene_names_refseq": "SERPINA4; SPIA4", "protein_names_uniprotkb": "Corticosteroid binding globulin; Serpin family A member 1", "protein_names_refseq": "corticosteroid binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 precursor; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4", "tax_id": 9031, "disease": "", "pathway": " (gga:423433); (R-GGA-194002); (R-GGA-9757110)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BX935008.1, SRR13267655.124756.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992428, SAMEA103992604 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On Dec 3, 2021 this sequence version replaced NP_001264421.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A160F7C1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A167VDT2-1", "uniprot_id": [ { "id": "A0A167VDT2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A167VDT2", "type": "external" } ], "mass": 76681.0, "length": 680, "protein_name": "Tumor protein 63 (p63)", "gene_name": "TP63", "organism": "Chicken", "refseq_name": "tumor protein 63 isoform 1", "refseq_ac": [ { "id": "NP_001385322", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385322", "type": "external" } ], "gene_names_uniprotkb": "TP63", "gene_names_refseq": "TAp63alpha; TP63; TP73L; TRP63; deltaNp63; p63", "protein_names_uniprotkb": "Tumor protein 63 (p63)", "protein_names_refseq": "DeltaNp63alpha; transformation related protein 63; tumor protein 63 isoform 1; tumor protein 63", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-6804759)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "25403071;30875434;35196980", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: MH238464.1, KU981085.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Dec 15, 2021 this sequence version replaced XP_015146847.1., [RefSeq]; Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Identifying pathways regulating the oncogenic p53 family member DeltaNp63 provides therapeutic avenues for squamous cell carcinoma. Publication Status: Online-Only, [RefSeq, PubMed]; Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression., [UniProtKB, UniProtKB]; Our analysis identified p63 as the most expressed member of the p53 gene family in areas of programmed cell death and senescence associated with the remodeling of the outflow tract to construct the roots of the great arteries and with septation of the cardiac cavities during the development of the heart in the chicken embryo., [RefSeq, PubMed]; The expression of p63 in nuclei of luminal cells was significantly higher in the infundibulum, compared to the magnum section., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0003684 damaged DNA binding;GO:0050699 WW domain binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:2000648 positive regulation of stem cell proliferation;GO:0045617 negative regulation of keratinocyte differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A167VDT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A172PWX7-1", "uniprot_id": [ { "id": "A0A172PWX7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A172PWX7", "type": "external" } ], "mass": 14585.0, "length": 139, "protein_name": "Neuropeptide W", "gene_name": "NPW", "organism": "Chicken", "refseq_name": "neuropeptide W", "refseq_ac": [ { "id": "XP_015149929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149929", "type": "external" } ], "gene_names_uniprotkb": "NPW", "gene_names_refseq": "NPW", "protein_names_uniprotkb": "Neuropeptide W", "protein_names_refseq": "neuropeptide W", "tax_id": 9031, "disease": "", "pathway": " (gga:101748764); (R-GGA-375276); (R-GGA-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149929.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0007631 feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A172PWX7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A172PWX8-1", "uniprot_id": [ { "id": "A0A172PWX8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A172PWX8", "type": "external" } ], "mass": 12317.0, "length": 119, "protein_name": "Anaphase promoting complex subunit 11; Neuropeptide B", "gene_name": "NPB", "organism": "Chicken", "refseq_name": "neuropeptide B precursor", "refseq_ac": [ { "id": "NP_001361262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001361262", "type": "external" } ], "gene_names_uniprotkb": "NPB; ANAPC11", "gene_names_refseq": "NPB", "protein_names_uniprotkb": "Anaphase promoting complex subunit 11; Neuropeptide B", "protein_names_refseq": "neuropeptide B precursor", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-375276); (R-GGA-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "27399877", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BU234290.1, BU206033.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## bicistronic transcript :: inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1, BX932383.1 and BU234290.1., [RefSeq]; Peptide of 28 amino acids widely expressed in chicken tissues, including hypothalamus, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0007631 feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A172PWX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A173G6H0-1", "uniprot_id": [ { "id": "A0A173G6H0_PIG", "url": "https://www.uniprot.org/uniprot/A0A173G6H0", "type": "external" } ], "mass": 42719.0, "length": 369, "protein_name": "Septin", "gene_name": "SEPTIN5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SEPTIN5", "gene_names_refseq": "", "protein_names_uniprotkb": "Septin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156312)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Filament-forming cytoskeletal GTPase., [UniProtKB, UniProtKB, UniProtKB]; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A1T3", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding;GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005940 septin ring;GO:0005886 plasma membrane;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0051301 cell division;GO:0008104 protein localization;GO:0061640 cytoskeleton-dependent cytokinesis;GO:0017157 regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A173G6H0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000010000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A178U9T0-1", "uniprot_id": [ { "id": "SOP16_ARATH", "url": "https://www.uniprot.org/uniprot/A0A178U9T0", "type": "external" } ], "mass": 8112.0, "length": 74, "protein_name": "Serine rich endogenous peptide 16", "gene_name": "PROSCOOP16", "organism": "Arabidopsis", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001330341", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001330341", "type": "external" } ], "gene_names_uniprotkb": "PROSCOOP16; MLF18; SCOOP16", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine rich endogenous peptide 16; AtSCOOP16; Phytocytokine SCOOP16; Precursor of serine rich endogenous peptide phytocytokine 16", "protein_names_refseq": "uncharacterized protein", "tax_id": 3702, "disease": "", "pathway": " (ath:AT5G36907)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10048488;27862469;30715439;34535661", "class_list": "", "function": "Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1P8BAI7", "ec_number_list": [], "go_molecular_function": "GO:0033612 receptor serine/threonine kinase binding;GO:0030275 LRR domain binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048046 apoplast", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A178U9T0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.1000000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A178UDM7-1", "uniprot_id": [ { "id": "A0A178UDM7_ARATH", "url": "https://www.uniprot.org/uniprot/A0A178UDM7", "type": "external" } ], "mass": 19176.0, "length": 171, "protein_name": "Transcription factor bHLH140-like protein", "gene_name": "ROX", "organism": "Arabidopsis", "refseq_name": "transcription factor bHLH140-like protein", "refseq_ac": [ { "id": "NP_001331183", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001331183", "type": "external" } ], "gene_names_uniprotkb": "ROX", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor bHLH140-like protein", "protein_names_refseq": "transcription factor bHLH140-like protein", "tax_id": 3702, "disease": "", "pathway": " (ath:AT5G01305)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11130714;27862469", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1P8BD33", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0090506 axillary shoot meristem initiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A178UDM7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.1000000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A178UFC4-1", "uniprot_id": [ { "id": "A0A178UFC4_ARATH", "url": "https://www.uniprot.org/uniprot/A0A178UFC4", "type": "external" } ], "mass": 13164.0, "length": 113, "protein_name": "Uncharacterized protein", "gene_name": "", "organism": "Arabidopsis", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001330757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001330757", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 3702, "disease": "", "pathway": " (ath:AT5G65613)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11130714;27862469", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1P8BBT8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A178UFC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.1000000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A178UIE7-1", "uniprot_id": [ { "id": "A0A178UIE7_ARATH", "url": "https://www.uniprot.org/uniprot/A0A178UIE7", "type": "external" } ], "mass": 36427.0, "length": 322, "protein_name": "Histidine-tRNA ligase", "gene_name": "F21E1.10", "organism": "Arabidopsis", "refseq_name": "histidine-tRNA ligase", "refseq_ac": [ { "id": "NP_001331479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001331479", "type": "external" } ], "gene_names_uniprotkb": "F21E1.10", "gene_names_refseq": "F21E1.10", "protein_names_uniprotkb": "Histidine-tRNA ligase", "protein_names_refseq": "histidine-tRNA ligase", "tax_id": 3702, "disease": "", "pathway": " (ath:AT5G04090)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11130714;27862469", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1P8AVS8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A178WKG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.1000000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A181-1", "uniprot_id": [ { "id": "A0A181_DANRE", "url": "https://www.uniprot.org/uniprot/A0A181", "type": "external" } ], "mass": 12678.0, "length": 112, "protein_name": "Somatoliberin", "gene_name": "ghrh", "organism": "Zebrafish", "refseq_name": "somatoliberin precursor", "refseq_ac": [ { "id": "NP_001073561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073561", "type": "external" } ], "gene_names_uniprotkb": "ghrh; GHRH", "gene_names_refseq": "ghrh", "protein_names_uniprotkb": "Somatoliberin; Growth 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"class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DQ832172.1, DQ991246.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505377, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ832172.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1Y2B6", "ec_number_list": [], "go_molecular_function": "GO:0031770 growth hormone-releasing hormone receptor binding;GO:0005184 neuropeptide hormone activity;GO:0051428 peptide hormone receptor binding;GO:0016608 growth hormone-releasing hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043195 terminal bouton;GO:0043204 perikaryon", "go_biological_process": "GO:0007165 signal transduction;GO:0032880 regulation of protein localization;GO:0030252 growth hormone secretion;GO:0141163 positive regulation of cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A181-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A182-1", "uniprot_id": [ { "id": "A0A182_DANRE", "url": "https://www.uniprot.org/uniprot/A0A182", "type": "external" } ], "mass": 51041.0, "length": 445, "protein_name": "Growth hormone-releasing hormone receptor", "gene_name": "ghrhrl", "organism": "Zebrafish", "refseq_name": "growth hormone releasing hormone receptor, like precursor", "refseq_ac": [ { "id": "NP_001075951", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075951", "type": "external" } ], "gene_names_uniprotkb": "ghrhrl; GHRHR; ghrhr", "gene_names_refseq": "ghrhrl; ghrhr", "protein_names_uniprotkb": "Growth hormone-releasing hormone receptor; Growth hormone-releasing factor receptor", "protein_names_refseq": "growth hormone releasing hormone receptor, like precursor; growth hormone-releasing hormone receptor", "tax_id": 7955, "disease": "isolated growth hormone deficiency (Disease Ontology:DOID:0060870); isolated growth hormone deficiency type IB (Disease Ontology:DOID:0060874); sleep disorder (Disease Ontology:DOID:535)", "pathway": " (dre:793334); (R-DRE-420092)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "17283332;18757498;23308232;23594743;25841489", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DQ991247.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505390, SAMEA4476746 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ991247.1. On Mar 11, 2007 this sequence version replaced XP_001333072.1., [RefSeq]; Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019838 growth factor binding;GO:0017046 peptide hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0016520 growth hormone-releasing hormone receptor activity;GO:0004999 vasoactive intestinal polypeptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0032868 response to insulin;GO:0040018 positive regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A182-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A182B7B1-1", "uniprot_id": [ { "id": "A0A182B7B1_PIG", "url": "https://www.uniprot.org/uniprot/A0A182B7B1", "type": "external" } ], "mass": 66558.0, "length": 642, "protein_name": "Transcription factor E2-alpha", "gene_name": "TCF3", "organism": "Pig", "refseq_name": "transcription factor E2-alpha isoform X1", "refseq_ac": [ { "id": "XP_020939882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939882", "type": "external" } ], "gene_names_uniprotkb": "TCF3", "gene_names_refseq": "TCF3", "protein_names_uniprotkb": "Transcription factor E2-alpha; Transcription factor 3", "protein_names_refseq": "transcription factor E2-alpha isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-525793); (R-SSC-8939236)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "30723633", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0033152 immunoglobulin V(D)J recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A182B7B1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A183-1", "uniprot_id": [ { "id": "LCE6A_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A183", "type": "external" } ], "mass": 9022.0, "length": 80, "protein_name": "Late cornified envelope protein 6A", "gene_name": "LCE6A", "organism": "Human", "refseq_name": "late cornified envelope protein 6A", "refseq_ac": [ { "id": "NP_001122072", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122072", "type": "external" } ], "gene_names_uniprotkb": "LCE6A; C1orf44", "gene_names_refseq": "C1orf44; LCE6A", "protein_names_uniprotkb": "Late cornified envelope protein 6A", "protein_names_refseq": "late cornified envelope protein 6A", "tax_id": 9606, "disease": "", "pathway": " (hsa:448835); (R-HSA-6809371)", "pathway_count": 2, "publication_count": 39, "publication_id_list": "10066784;10196183;10231017;10411887;10588656;10771479;11350120;11380615;11590230;12902340;15033990;15337775;15797384;15803139;15854049;16061697;16639001;17515931;17562024;17596512;18843291;19190773;19194479;20179351;20657595;20667819;20940292;21439340;21654840;21997417;23629652;25926655;26390218;37340703;7543090;8824274;8999895;9395522;9565599", "class_list": "", "function": "Describes neighboring LCE family members that are present in the same cluster on chromosome 1q21., [RefSeq, PubMed]; Precursors of the cornified envelope of the stratum corneum., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 4, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0031424 keratinization", "synthesized_glycan_count": 0, "hit_score": 4.3, "record_id": "A0A183-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A191URJ7-1", "uniprot_id": [ { "id": "A0A191URJ7_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A191URJ7", "type": "external" } ], "mass": 39875.0, "length": 360, "protein_name": "KIR2DL protein; Killer cell immunoglobulin-like receptor", "gene_name": "KIR2DL1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KIR2DL1; 3DL2", "gene_names_refseq": "", "protein_names_uniprotkb": "KIR2DL protein; Killer cell immunoglobulin-like receptor", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 2, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002764 immune response-regulating signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A191URJ7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000001000000.0000000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A193GP06-1", "uniprot_id": [ { "id": "A0A193GP06_DANRE", "url": "https://www.uniprot.org/uniprot/A0A193GP06", "type": "external" } ], "mass": 299371.0, "length": 2733, "protein_name": "Thyroglobulin", "gene_name": "tg", "organism": "Zebrafish", "refseq_name": "thyroglobulin precursor", "refseq_ac": [ { "id": "NP_001316794", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316794", "type": "external" } ], "gene_names_uniprotkb": "tg; Tg; cb717", "gene_names_refseq": "cb717; tg", "protein_names_uniprotkb": "Thyroglobulin", "protein_names_refseq": "thyroglobulin precursor", "tax_id": 7955, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); isolated growth hormone deficiency (Disease Ontology:DOID:0060870); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); thyroid dyshormonogenesis 3 (Disease Ontology:DOID:0112187); goiter (Disease Ontology:DOID:12176); Graves' disease (Disease Ontology:DOID:12361); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); hypothyroidism (Disease Ontology:DOID:1459); autoimmune thyroiditis (Disease Ontology:DOID:7188)", "pathway": " (dre:567631)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "16680726;17640903;18498112;19703701;19945756;23594743;27311711;35681818;36150888;36824359;36994096;37600710", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KU662327.1, GDQH01022497.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KU662327.1. On Aug 2, 2016 this sequence version replaced XP_694292.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0042446 hormone biosynthetic process;GO:0006590 thyroid hormone generation;GO:2000609 regulation of thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A193GP06-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A193KX02-1", "uniprot_id": [ { "id": "TOMT_DANRE", "url": "https://www.uniprot.org/uniprot/A0A193KX02", "type": "external" } ], "mass": 29608.0, "length": 259, "protein_name": "Transmembrane O-methyltransferase homolog", "gene_name": "tomt", "organism": "Zebrafish", "refseq_name": "transmembrane O-methyltransferase homolog", "refseq_ac": [ { "id": "NP_001411114", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411114", "type": "external" } ], "gene_names_uniprotkb": "tomt; mercury; mrc", "gene_names_refseq": "mercury; mrc; tomt", "protein_names_uniprotkb": "Transmembrane O-methyltransferase homolog; 2.1.1.6; Protein mercury", "protein_names_refseq": "protein mercury; transmembrane O-methyltransferase homolog", "tax_id": 7955, "disease": "autosomal recessive nonsyndromic deafness 63 (Disease Ontology:DOID:0110515)", "pathway": " (dre:110437932); (R-DRE-379397)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10526320;23594743;28534737;33376159;36161311;9491988", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KX066099.1, SRR32588722.2643588.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476740 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Sep 8, 2023 this sequence version replaced XP_021322195.1., [RefSeq]; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity (PubMed:28534737)., [UniProtKB, PubMed, UniProtKB]; The authors found that Tmc1/2 proteins are specifically excluded from the hair bundle in tomt mutants, whereas other mechanotransduction complex proteins can still localize to the bundle. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0016206 catechol O-methyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0031223 auditory behavior;GO:0006897 endocytosis;GO:0032502 developmental process;GO:0007605 sensory perception of sound;GO:0042417 dopamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A193KX02-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GQX2-1", "uniprot_id": [ { "id": "TUNAR_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A1B0GQX2", "type": "external" } ], "mass": 5288.0, "length": 48, "protein_name": "Protein TUNAR", "gene_name": "Tunar", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tunar", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein TUNAR; BNLN; Beta cell and neural cell-regulin; Tcl1 upstream neural differentiation-associated RNA; pTUNAR", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "35036403", "class_list": "", "function": "In neurons, plays a role in the regulation of intracellular Ca(2+), possibly by acting as an activator of ATP2A2/SERCA2, thus increasing the efficiency with which Ca(2+) is removed from the cytoplasm (PubMed:35036403). Inhibits differentiation of embryonic stem cells into neurons and inhibits neurite outgrowth, likely as a result of its role in intracellular Ca(2+) regulation (PubMed:35036403). In pancreatic beta cells, lowers Ca(2+) levels in the endoplasmic reticulum and enhances glucose-stimulated insulin secretion (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045665 negative regulation of neuron differentiation;GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0048812 neuron projection morphogenesis;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0032469 endoplasmic reticulum calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1B0GQX2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "uniprot_id": [ { "id": "CTXD2_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A1B0GQX3", "type": "external" } ], "mass": 6518.0, "length": 59, "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "organism": "Mouse", "refseq_name": "cortexin domain containing 2", "refseq_ac": [ { "id": "NP_001371119", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001371119", "type": "external" } ], "gene_names_uniprotkb": "Ctxnd2", "gene_names_refseq": "4930558C23Rik; 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Involved in membrane fusion downstream of the lipid mixing step mediated by MYMK (By similarity). Acts by generating membrane stresses via its extracellular C-terminus, leading to drive fusion pore formation. Acts independently of MYMK (By similarity). Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed]; This articles reviews and discusses the latest studies related to Myomaker and Myomixer-Myomerger-Minion, including the discovery, structure, expression pattern, functions of the two proteins. 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Erratum:[Nat Genet. 2022 Jun;54(6):906. doi: 10.1038/s41588-022-01053-8. 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GVQ0-1", "uniprot_id": [ { "id": "SPAR_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A1B0GVQ0", "type": "external" } ], "mass": 9632.0, "length": 90, "protein_name": "Small regulatory polypeptide of amino acid response", "gene_name": "SPAAR", "organism": "Human", "refseq_name": "small regulatory polypeptide of amino acid response", "refseq_ac": [ { "id": "NP_001335036", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335036", "type": "external" } ], "gene_names_uniprotkb": "SPAAR; LINC00961; SPAR", "gene_names_refseq": "LINC00961; SPAAR; SPAR", "protein_names_uniprotkb": "Small regulatory polypeptide of amino acid response", "protein_names_refseq": "long intergenic non-protein coding RNA 961; small regulatory polypeptide of amino acid response; small regulatory polypeptide of amino acids response", "tax_id": 9606, "disease": "", "pathway": " (hsa:158376)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "28024296;29156520;30070327;30367453;31990292;32045135;34946813;35244469;35656895", "class_list": "", "function": "Data provide a mechanism by which mTORC1 activation may be finely regulated in a tissue-specific manner in response to injury, and a paradigm by which lncRNAs encoding small polypeptides like SPAR can modulate general biological pathways and processes to facilitate tissue-specific requirements, consistent with their restricted and highly regulated expression profile, [RefSeq, PubMed]; Decreased LINC00961 might play a key role in non-small cell lung cancer (NSCLC) progression, and may serve as a novel prognostic marker in human NSCLC, [RefSeq, PubMed]; Dysregulated LINC00961 Contributes to the Vitality and Migration of NSCLC Via miR-19a-3p/miR-19b-3p/miR-125b-5p., [RefSeq, PubMed]; Evolutionary Characterization of the Short Protein SPAAR. Publication Status: Online-Only, [RefSeq, PubMed]; LINC00961 inhibits the migration and invasion of colon cancer cells by sponging miR-223-3p and targeting SOX11., [RefSeq, PubMed]; LINC00961 is involved in renal cell carcinoma progression by targeting the epithelial-mesenchymal transition pathway., [RefSeq, PubMed]; LncRNA LINC00961 regulates endothelialmesenchymal transition via the PTENPI3KAKT pathway., [RefSeq, PubMed]; Negative regulator of amino acid sensing and mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels and amino acids (PubMed:28024296). Negatively regulates mTORC1 activation by inhibiting recruitment of mTORC1 to lysosomes upon stimulation with amino acids: acts by promoting the formation of a tightly bound supercomplex composed of the lysosomal V-ATPase, Ragulator and Rag GTPases, preventing recruitment of mTORC1 (PubMed:28024296). Acts as a regulator of muscle regeneration following injury by regulating mTORC1 activation (By similarity)., [UniProtKB, PubMed, UniProtKB]; Overexpression of LINC00961 significantly suppressed glioma cells proliferation, migration, and invasion. 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Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1B0GWG4-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWH4-1", "uniprot_id": [ { "id": "HSFX3_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A1B0GWH4", "type": "external" } ], "mass": 37128.0, "length": 333, "protein_name": "Heat shock transcription factor, X-linked member 3", "gene_name": "HSFX3", "organism": "Human", "refseq_name": "heat shock transcription factor, X-linked member 3", "refseq_ac": [ { "id": "NP_001310008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001310008", "type": "external" } ], "gene_names_uniprotkb": "HSFX3", "gene_names_refseq": "HSFX3", "protein_names_uniprotkb": "Heat shock transcription factor, X-linked member 3", "protein_names_refseq": "heat shock transcription factor, X-linked member 3; heat shock transcription factor, X-linked-like", "tax_id": 9606, "disease": "", "pathway": " (hsa:101928917)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWH4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWH6-1", "uniprot_id": [ { "id": "LSP1N_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A1B0GWH6", "type": "external" } ], "mass": 2949.0, "length": 25, "protein_name": "LASP1 neighbor protein", "gene_name": "LASP1NB", "organism": "Human", "refseq_name": "LASP1 neighbor protein", "refseq_ac": [ { "id": "NP_001401626", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401626", "type": "external" } ], "gene_names_uniprotkb": "LASP1NB; LINC00672", "gene_names_refseq": "LASP1NB; LINC00672", "protein_names_uniprotkb": "LASP1 neighbor protein; Long intergenic non-protein coding RNA 672", "protein_names_refseq": "LASP1 neighbor protein; long intergenic non-protein coding RNA 672", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "28232485;31410210", "class_list": "", "function": "May play a key role in the skin fibroblasts (FBs)-keratinocyte-like cells (KLCs)., [UniProtKB, PubMed]; These findings indicate that LINC00672 can influence LASP1 expression as a locus-restricted cofactor for p53-mediated gene suppression, thus impacting endometrial cancer and chemosensitivity to paclitaxel., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1B0GWH6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWI6-1", "uniprot_id": [ { "id": "A0A1B0GWI6_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A1B0GWI6", "type": "external" } ], "mass": 55104.0, "length": 518, "protein_name": "Uncharacterized protein", "gene_name": "LOC101059915", "organism": "Human", "refseq_name": "uncharacterized protein LOC101059915", "refseq_ac": [ { "id": "NP_001310004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001310004", "type": "external" } ], "gene_names_uniprotkb": "LOC101059915", "gene_names_refseq": "CXorf49C", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "chromosome X open reading frame 49-like; uncharacterized protein CXorf49-like; uncharacterized protein LOC101059915", "tax_id": 9606, "disease": "", "pathway": " (hsa:101059915)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11237011;32938616", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1B0GWI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWK0-1", "uniprot_id": [ { "id": "PVLEF_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A1B0GWK0", "type": "external" } ], "mass": 15275.0, "length": 134, "protein_name": "Parvalbumin-like EF-hand-containing protein", "gene_name": "PVALEF", "organism": "Human", "refseq_name": "parvalbumin-like EF-hand-containing protein", "refseq_ac": [ { "id": "NP_001341568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001341568", "type": "external" } ], "gene_names_uniprotkb": "PVALEF", "gene_names_refseq": "AATK-AS1; PVALEF", "protein_names_uniprotkb": "Parvalbumin-like EF-hand-containing protein", "protein_names_refseq": "AATK antisense RNA 1 (non-protein coding); parvalbumin-like EF-hand-containing protein", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "32938616;35051231", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005861 troponin complex", "go_biological_process": "GO:0003009 skeletal muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1B0GWK0-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWM3-1", "uniprot_id": [ { "id": "A0A1B0GWM3_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWM3", "type": "external" } ], "mass": 366059.0, "length": 3333, "protein_name": "Laminin subunit alpha 3", "gene_name": "Lama3", "organism": "Rat", "refseq_name": "laminin subunit alpha-3 isoform B precursor", "refseq_ac": [ { "id": "NP_001380677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001380677", "type": "external" } ], "gene_names_uniprotkb": "Lama3", "gene_names_refseq": "Lama3", "protein_names_uniprotkb": "Laminin subunit alpha 3", "protein_names_refseq": "laminin 5 alpha 3; laminin subunit alpha-3 isoform B precursor; laminin, alpha 3", "tax_id": 10116, "disease": "junctional epidermolysis bullosa non-Herlitz type (Disease Ontology:DOID:0060738); junctional epidermolysis bullosa (Disease Ontology:DOID:3209); lung small cell carcinoma (Disease Ontology:DOID:5409)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "20039268;20301201", "class_list": "", "function": "Binding sites for alpha3beta1 and alpha6beta4 are closely spaced in the Ln-332 LG domains where they regulate alternative cell functions, namely adhesion/migration or hemidesmosome anchoring., [RefSeq, PubMed]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]; In bladder carcinoma laminin-332 can suppress the number of invadopodia that form by interacting with a3b1 integrin and altering the cellular balance of FAK and Src kinase activity., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0005912 adherens junction;GO:0005604 basement membrane;GO:0030056 hemidesmosome;GO:0005608 laminin-3 complex", "go_biological_process": "GO:0030155 regulation of cell adhesion;GO:0098609 cell-cell adhesion;GO:0030334 regulation of cell migration;GO:0031581 hemidesmosome assembly;GO:0045995 regulation of embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1B0GWM3-1", "record_type": "protein", "filter_code": "0000000.0000110.001000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWP1-1", "uniprot_id": [ { "id": "A0A1B0GWP1_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWP1", "type": "external" } ], "mass": 47306.0, "length": 412, "protein_name": "Elongation of very long chain fatty acids protein 1", "gene_name": "Elovl1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Elovl1; ELOVL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 1; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "adrenoleukodystrophy (Disease Ontology:DOID:10588)", "pathway": " (R-RNO-2046105); (R-RNO-2046106); (R-RNO-75876)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0061436 establishment of skin barrier;GO:0030148 sphingolipid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0019367 fatty acid elongation, saturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWP1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWQ8-1", "uniprot_id": [ { "id": "A0A1B0GWQ8_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWQ8", "type": "external" } ], "mass": 183886.0, "length": 1733, "protein_name": "Methyl-CpG-binding domain protein 5", "gene_name": "Mbd5", "organism": "Rat", "refseq_name": "methyl-CpG-binding domain protein 5 isoform X1", "refseq_ac": [ { "id": "XP_056841390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_056841390", "type": "external" } ], "gene_names_uniprotkb": "Mbd5", "gene_names_refseq": "Mbd5", "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 5; Methyl-CpG-binding protein MBD5", "protein_names_refseq": "methyl-CpG-binding domain protein 5 isoform X1", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal dominant intellectual developmental disorder (Disease Ontology:DOID:0060307); autosomal dominant intellectual developmental disorder 1 (Disease Ontology:DOID:0070031)", "pathway": " (R-RNO-5689603)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-120' (H2AK119ub1). Important for stability of PR-DUB components and stimulating its ubiquitinase activity. As part of the PR-DUB complex, associates with chromatin enriched in histone marks H3K4me1, H3K4me3, and H3K27Ac, but not in H3K27me3. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in cell growth and survivability. MBD5 and MBD6 containing complexes associate with distinct chromatin regions enriched in genes involved in different pathways. Heterochromatin recruitment is not mediated by DNA methylation. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in development, cell communication, signaling, cell proliferation and cell viability., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWR7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWR9-1", "uniprot_id": [ { "id": "A0A1B0GWR9_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWR9", "type": "external" } ], "mass": 135299.0, "length": 1194, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp8b4", "organism": "Rat", "refseq_name": "probable phospholipid-transporting ATPase IM", "refseq_ac": [ { "id": "NP_001417363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417363", "type": "external" } ], "gene_names_uniprotkb": "Atp8b4", "gene_names_refseq": "Atp8b4", "protein_names_uniprotkb": "Phospholipid-transporting 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"external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005802 trans-Golgi network;GO:1990531 phospholipid-translocating ATPase complex", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWR9-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWT2-1", "uniprot_id": [ { "id": "A0A1B0GWT2_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWT2", "type": "external" } ], "mass": 290975.0, "length": 2543, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp9y", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Usp9y", "gene_names_refseq": "", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "", "tax_id": 10116, "disease": "Y-linked spermatogenic failure 2 (Disease Ontology:DOID:0070187); female-restricted syndromic X-linked intellectual disability 99 (Disease Ontology:DOID:0112025); non-syndromic X-linked intellectual disability 99 (Disease Ontology:DOID:0112026)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. 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"0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWT9-1", "uniprot_id": [ { "id": "A0A1B0GWT9_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWT9", "type": "external" } ], "mass": 56038.0, "length": 485, "protein_name": "Tripartite motif containing 68", "gene_name": "Trim68", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase TRIM68", "refseq_ac": [ { "id": "NP_001388433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388433", "type": "external" } ], "gene_names_uniprotkb": "Trim68", "gene_names_refseq": "Trim68", "protein_names_uniprotkb": "Tripartite motif containing 68", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM68", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0090619 meiotic spindle pole;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0051301 cell division;GO:0001822 kidney development;GO:0003281 ventricular septum development;GO:0035904 aorta development;GO:0060976 coronary vasculature development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWU0-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWV7-1", "uniprot_id": [ { "id": "A0A1B0GWV7_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWV7", "type": "external" } ], "mass": 98724.0, "length": 885, "protein_name": "Bardet-Biedl syndrome 9", "gene_name": "Bbs9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bbs9", "gene_names_refseq": "", "protein_names_uniprotkb": "Bardet-Biedl syndrome 9", "protein_names_refseq": "", "tax_id": 10116, "disease": "Bardet-Biedl syndrome 9 (Disease Ontology:DOID:0110131); Bardet-Biedl syndrome (Disease Ontology:DOID:1935); craniosynostosis (Disease Ontology:DOID:2340); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (R-RNO-5620922)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005929 cilium;GO:0016020 membrane;GO:0034451 centriolar satellite;GO:0060170 ciliary membrane;GO:0034464 BBSome", "go_biological_process": "GO:0060271 cilium assembly;GO:0045444 fat cell differentiation;GO:0061512 protein localization to cilium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWV7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWW4-1", "uniprot_id": [ { "id": "A0A1B0GWW4_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWW4", "type": "external" } ], "mass": 126668.0, "length": 1125, "protein_name": "Cytosolic carboxypeptidase 4", "gene_name": "Agbl1", "organism": "Rat", "refseq_name": "AGBL carboxypeptidase 1 isoform 1", "refseq_ac": [ { "id": "NP_001419181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419181", "type": "external" } ], "gene_names_uniprotkb": "Agbl1", "gene_names_refseq": "Agbl1; 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Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.17.24", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.24", "type": "external" }, { "id": "3.4.17.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity;GO:0015631 tubulin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWW4-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWY2-1", "uniprot_id": [ { "id": "A0A1B0GWY2_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWY2", "type": "external" } ], "mass": 91234.0, "length": 803, "protein_name": "Zinc finger protein 1, Y-linked", "gene_name": "Zfy1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfy1", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 1, Y-linked", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043035 chromatin insulator sequence binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007281 germ cell development;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWY2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWY7-1", "uniprot_id": [ { "id": "A0A1B0GWY7_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWY7", "type": "external" } ], "mass": 45316.0, "length": 409, "protein_name": "TNF receptor-associated factor", "gene_name": "Traf1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Traf1", "gene_names_refseq": "", "protein_names_uniprotkb": "TNF receptor-associated factor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5357905); 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Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0031996 thioesterase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009898 cytoplasmic side of plasma membrane;GO:0035631 CD40 receptor complex", "go_biological_process": "GO:0006915 apoptotic process;GO:2001236 regulation of extrinsic apoptotic signaling pathway;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0043122 regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWY7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GX31-1", "uniprot_id": [ { "id": "TVB76_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A1B0GX31", "type": "external" } ], "mass": 12827.0, "length": 115, "protein_name": "T cell receptor beta variable 7-6", "gene_name": "TRBV7-6", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV7-6", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor beta variable 7-6", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A1B0GXF2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B1LZI1-1", "uniprot_id": [ { "id": "A0A1B1LZI1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1B1LZI1", "type": "external" } ], "mass": 158539.0, "length": 1414, "protein_name": "protein-tyrosine-phosphatase", "gene_name": "ptprga", "organism": "Zebrafish", "refseq_name": "receptor-type tyrosine-protein phosphatase gamma precursor", "refseq_ac": [ { "id": "NP_001316793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316793", "type": "external" } ], "gene_names_uniprotkb": "ptprga; R-PTP-gamma", "gene_names_refseq": "R-PTP-gamma; ptprga", "protein_names_uniprotkb": "protein-tyrosine-phosphatase; 3.1.3.48", "protein_names_refseq": "protein tyrosine phosphatase, receptor type, g a; receptor-type tyrosine-protein phosphatase gamma precursor; receptor-type tyrosine-protein phosphatase gamma", "tax_id": 7955, "disease": "", "pathway": " (dre:561197)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "20838449;23594743;23698347;23974070;26469318;28814789", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KU519108.1, GDQH01011151.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476782, SAMEA4476784 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KU519108.1. On Aug 2, 2016 this sequence version replaced XP_009304073.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z044", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NS27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NS34-1", "uniprot_id": [ { "id": "A0A1D5NS34_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NS34", "type": "external" } ], "mass": 90810.0, "length": 809, "protein_name": "RPA-related protein RADX; Si:ch73-71d17.2", "gene_name": "si:ch73-71d17.2", "organism": "Zebrafish", "refseq_name": "RPA-related protein RADX isoform X1", "refseq_ac": [ { "id": "XP_021333418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333418", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-71d17.2", "gene_names_refseq": "si:ch73-71d17.2", "protein_names_uniprotkb": "RPA-related protein RADX; Si:ch73-71d17.2", "protein_names_refseq": "RPA-related protein RADX isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100535117)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q286", "ec_number_list": [], "go_molecular_function": "GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005657 replication fork", "go_biological_process": "GO:0006282 regulation of DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NS34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NS60-1", "uniprot_id": [ { "id": "ZN16L_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NS60", "type": "external" } ], "mass": 58861.0, "length": 528, "protein_name": "Zinc finger protein 16-like", "gene_name": "znf16l", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "znf16l; si:ch211-108m2.2; znf697l", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 16-like; Zinc finger protein 697-like", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:570544)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;26459222", "class_list": "", "function": "Probable transcription factor (Probable). Important for development and migration of oligodendrocyte precursor cells, and normal myelination of axons in the central nervous system (CNS) (PubMed:26459222). Functions autonomously in oligodendrocytes to promote CNS myelination (PubMed:26459222). 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGY3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NS78-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NS95-1", "uniprot_id": [ { "id": "A0A1D5NS95_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NS95", "type": "external" } ], "mass": 63772.0, "length": 552, "protein_name": "Bloodthirsty-related gene family, member 7; E3 ubiquitin-protein ligase TRIM39", "gene_name": "btr07", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase TRIM39 isoform X1", "refseq_ac": [ { "id": "XP_017212469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212469", "type": "external" } ], "gene_names_uniprotkb": "btr07", "gene_names_refseq": "btr07", "protein_names_uniprotkb": "Bloodthirsty-related gene family, member 7; E3 ubiquitin-protein ligase TRIM39", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM39 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:793570); (R-DRE-3232142); (R-DRE-8948751); (R-DRE-983168)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z1N3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NS95-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSA3-1", "uniprot_id": [ { "id": "A0A1D5NSA3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSA3", "type": "external" } ], "mass": 56081.0, "length": 491, "protein_name": "E3 ubiquitin-protein ligase TRIM39; Si:dkey-183c6.9", "gene_name": "si:dkey-183c6.9", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase TRIM62", "refseq_ac": [ { "id": "XP_005172380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172380", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-183c6.9", "gene_names_refseq": "si:dkey-183c6.9", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM39; Si:dkey-183c6.9", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM62", "tax_id": 7955, "disease": "", "pathway": " (dre:101883673)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJN1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSC3-1", "uniprot_id": [ { "id": "A0A1D5NSC3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSC3", "type": "external" } ], "mass": 88145.0, "length": 791, "protein_name": "protein O-GlcNAcase", "gene_name": "si:dkey-183c6.8", "organism": "Zebrafish", "refseq_name": "protein O-GlcNAcase", "refseq_ac": [ { "id": "XP_017212504", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212504", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-183c6.8", "gene_names_refseq": "si:dkey-183c6.8", "protein_names_uniprotkb": "protein O-GlcNAcase; 3.2.1.169; Beta-N-acetylhexosaminidase; Beta-hexosaminidase", "protein_names_refseq": "protein O-GlcNAcase", "tax_id": 7955, "disease": "", "pathway": " (dre:100538182)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z1P7", "ec_number_list": [ { "id": "3.2.1.169", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.169", "type": "external" } ], "go_molecular_function": "GO:0102571 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity;GO:0015929 hexosaminidase activity", "go_cellular_component": "", "go_biological_process": "GO:0009100 glycoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSC5-1", "uniprot_id": [ { "id": "A0A1D5NSC5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSC5", "type": "external" } ], "mass": 121098.0, "length": 1083, "protein_name": "Transcriptional repressor NF-X1", "gene_name": "nfx1", "organism": "Zebrafish", "refseq_name": "transcriptional repressor NF-X1", "refseq_ac": [ { "id": "XP_690559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690559", "type": "external" } ], "gene_names_uniprotkb": "nfx1", "gene_names_refseq": "nfx1", "protein_names_uniprotkb": "Transcriptional repressor NF-X1; Nuclear transcription factor, X box-binding protein 1", "protein_names_refseq": "transcriptional repressor NF-X1", "tax_id": 7955, "disease": "", "pathway": " (dre:562071)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690559.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TB18", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016740 transferase activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSC5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSC9-1", "uniprot_id": [ { "id": "A0A1D5NSC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSC9", "type": "external" } ], "mass": 49365.0, "length": 433, "protein_name": "gamma-butyrobetaine dioxygenase", "gene_name": "bbox1", "organism": "Zebrafish", "refseq_name": "gamma-butyrobetaine dioxygenase isoform X1", "refseq_ac": [ { "id": "XP_005168960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168960", "type": "external" } ], "gene_names_uniprotkb": "bbox1; wu:fj14g08; zgc:112179", "gene_names_refseq": "bbox1; wu:fj14g08; zgc:112179", "protein_names_uniprotkb": "gamma-butyrobetaine dioxygenase; 1.14.11.1; Gamma-butyrobetaine hydroxylase; Gamma-butyrobetaine,2-oxoglutarate dioxygenase", "protein_names_refseq": "gamma-butyrobetaine dioxygenase isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:572649); (R-DRE-71262)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "17196583;23594743;27189481;28102299;29867554;31468037", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of L-carnitine from gamma-butyrobetaine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG71", "ec_number_list": [ { "id": "1.14.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0008336 gamma-butyrobetaine dioxygenase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0045329 carnitine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A1D5NSC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSF9-1", "uniprot_id": [ { "id": "A0A1D5NSF9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSF9", "type": "external" } ], "mass": 19551.0, "length": 171, "protein_name": "Si:dkey-19b23.15; Thialysine N-epsilon-acetyltransferase", "gene_name": "sat2a.1", "organism": "Zebrafish", "refseq_name": "thialysine N-epsilon-acetyltransferase", "refseq_ac": [ { "id": "XP_021333451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333451", "type": "external" } ], "gene_names_uniprotkb": "sat2a.1", "gene_names_refseq": "sat2a.1", "protein_names_uniprotkb": "Si:dkey-19b23.15; Thialysine N-epsilon-acetyltransferase", "protein_names_refseq": "thialysine N-epsilon-acetyltransferase", "tax_id": 7955, "disease": "", "pathway": " (dre:569184)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVL9", "ec_number_list": [], "go_molecular_function": "GO:0008080 N-acetyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0006595 polyamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSJ6-1", "uniprot_id": [ { "id": "A0A1D5NSJ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSJ6", "type": "external" } ], "mass": 43695.0, "length": 393, "protein_name": "Growth arrest-specific 2b; Growth arrest-specific protein 2", "gene_name": "gas2b", "organism": "Zebrafish", "refseq_name": "growth arrest-specific protein 2", "refseq_ac": [ { "id": "XP_002662883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662883", "type": "external" } ], "gene_names_uniprotkb": "gas2b", "gene_names_refseq": "gas2b", "protein_names_uniprotkb": "Growth arrest-specific 2b; Growth arrest-specific protein 2", "protein_names_refseq": "growth arrest-specific protein 2", "tax_id": 7955, "disease": "autosomal recessive nonsyndromic deafness 125 (Disease Ontology:DOID:0061124); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (dre:567205); (R-DRE-264870)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHC3", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005856 cytoskeleton", "go_biological_process": "GO:0051764 actin crosslink formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSJ6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSK0-1", "uniprot_id": [ { "id": "CIROP_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSK0", "type": "external" } ], "mass": 69342.0, "length": 623, "protein_name": "Ciliated left-right organizer metallopeptidase", "gene_name": "cirop", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cirop; si:ch211-216p19.5", "gene_names_refseq": "", "protein_names_uniprotkb": "Ciliated left-right organizer metallopeptidase; 3.4.24.-; Leishmanolysin-like peptidase 2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100331300)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;34903892", "class_list": "", "function": "Plays an essential role for patterning the left-right axis. Requires solely on the left side, downstream of the leftward flow, but upstream of dand5, a nodal inhibitor involved in left-right patterning., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007155 cell adhesion;GO:0061371 determination of heart left/right asymmetry;GO:0061966 establishment of left/right asymmetry;GO:0007368 determination of left/right symmetry", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NSK0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSL4-1", "uniprot_id": [ { "id": "A0A1D5NSL4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSL4", "type": "external" } ], "mass": 57038.0, "length": 517, "protein_name": "Adenosine deaminase domain-containing 2; Adenosine deaminase domain-containing protein 2", "gene_name": "adad2", "organism": "Zebrafish", "refseq_name": "adenosine deaminase domain-containing protein 2", "refseq_ac": [ { "id": "XP_687183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687183", "type": "external" } ], "gene_names_uniprotkb": "adad2", "gene_names_refseq": "adad2", "protein_names_uniprotkb": "Adenosine deaminase domain-containing 2; Adenosine deaminase domain-containing protein 2", "protein_names_refseq": "adenosine deaminase domain-containing protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:558824)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TDG9", "ec_number_list": [], "go_molecular_function": "GO:0008251 tRNA-specific adenosine deaminase activity;GO:0003725 double-stranded RNA binding;GO:0003726 double-stranded RNA adenosine deaminase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006396 RNA processing;GO:0006382 adenosine to inosine editing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSL5-1", "uniprot_id": [ { "id": "A0A1D5NSL5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSL5", "type": "external" } ], "mass": 21888.0, "length": 193, "protein_name": "TRAF-interacting protein with FHA domain-containing protein A", "gene_name": "tifa", "organism": "Zebrafish", "refseq_name": "TRAF-interacting protein with FHA domain-containing protein A", "refseq_ac": [ { "id": "NP_001373475", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373475", "type": "external" } ], "gene_names_uniprotkb": "tifa; si:ch211-15b10.6", "gene_names_refseq": "si:ch211-15b10.6; tifa", "protein_names_uniprotkb": "TRAF-interacting protein with FHA domain-containing protein A", "protein_names_refseq": "TRAF-interacting protein with FHA domain-containing protein A", "tax_id": 7955, "disease": "", "pathway": " (dre:560548)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC086730.1, EH432683.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476810 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2025 this sequence version replaced NP_001373475.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJQ1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NSL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSM8-1", "uniprot_id": [ { "id": "SVEP1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSM8", "type": "external" } ], "mass": 393394.0, "length": 3615, "protein_name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "gene_name": "svep1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "svep1", "gene_names_refseq": "", "protein_names_uniprotkb": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; Polydom", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:567357)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23594743;27892606;28179430;28179432;35312765;37097004", "class_list": "", "function": "Required for embryonic lymphatic vascular development, via promotion of parachordal lymphangioblast development, cell alignment and migration both dorsally and ventrally (PubMed:28179430, PubMed:28179432, PubMed:37097004). Required for the formation of facial lymphatic structures and formation of brain lymphatic endothelial cells (PubMed:37097004). Acts in tandem with vegfa signaling to promote tip cell specification and the stabilization of lumenized vascular connections between neighboring arterial intersegmental vessel sprouts, thereby facilitating dorsal longitudinal anastomotic vessel formation in response to low blood flow (PubMed:35312765). Plays a role in epidermal differentiation, potentially via mediating cell-cell adhesion (PubMed:27892606)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 14, "predicted_n_glycosites": 13, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UV67", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0009913 epidermal cell differentiation;GO:0036303 lymph vessel morphogenesis;GO:0016477 cell migration;GO:0008544 epidermis development;GO:0001945 lymph vessel development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A1D5NSM8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.0000000000000001.0000000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSN1-1", "uniprot_id": [ { "id": "A0A1D5NSN1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSN1", "type": "external" } ], "mass": 11446.0, "length": 102, "protein_name": "Si:ch73-256g18.2; Small integral membrane protein 36", "gene_name": "si:ch73-256g18.2", "organism": "Zebrafish", "refseq_name": "small integral membrane protein 36", "refseq_ac": [ { "id": "XP_021336044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336044", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-256g18.2", "gene_names_refseq": "si:ch73-256g18.2", "protein_names_uniprotkb": "Si:ch73-256g18.2; Small integral membrane protein 36", "protein_names_refseq": "small integral membrane protein 36", "tax_id": 7955, "disease": "", "pathway": " (dre:557975)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QES5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSP6-1", "uniprot_id": [ { "id": "A0A1D5NSP6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSP6", "type": "external" } ], "mass": 17589.0, "length": 158, "protein_name": "Si:dkey-23i12.7; Uncharacterized protein LOC100007087; Uncharacterized protein isoform X1", "gene_name": "batf2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100007087", "refseq_ac": [ { "id": "NP_001373344", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373344", "type": "external" } ], "gene_names_uniprotkb": "batf2; si:dkey-23i12.7", "gene_names_refseq": "batf2; si:dkey-23i12.7", "protein_names_uniprotkb": "Si:dkey-23i12.7; Uncharacterized protein LOC100007087; Uncharacterized protein isoform X1", "protein_names_refseq": "basic leucine zipper transcriptional factor ATF-like; uncharacterized protein LOC100007087", "tax_id": 7955, "disease": "", "pathway": " (dre:100007087)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;31732531;33369805", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC153951.1, CN167505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505388, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PV20", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A1D5NSP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSP9-1", "uniprot_id": [ { "id": "A0A1D5NSP9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSP9", "type": "external" } ], "mass": 36628.0, "length": 334, "protein_name": "Prostaglandin reductase 1", "gene_name": "ptgr1.2", "organism": "Zebrafish", "refseq_name": "prostaglandin reductase 1 isoform X2", "refseq_ac": [ { "id": "XP_695372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695372", "type": "external" } ], "gene_names_uniprotkb": "ptgr1.2", "gene_names_refseq": "ptgr1.2", "protein_names_uniprotkb": "Prostaglandin reductase 1; 1.3.1.48; 1.3.1.74; 15-oxoprostaglandin 13-reductase; Dithiolethione-inducible gene 1 protein; Leukotriene B4 12-hydroxydehydrogenase; NAD(P)H-dependent alkenal/one oxidoreductase", "protein_names_refseq": "prostaglandin reductase 1 isoform X2", "tax_id": 7955, "disease": "hypertension (Disease Ontology:DOID:10763)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_695372.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TEC7", "ec_number_list": [ { "id": "1.3.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.74", "type": "external" }, { "id": "1.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.48", "type": "external" } ], "go_molecular_function": "GO:0032440 2-alkenal reductase [NAD(P)H] activity;GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006693 prostaglandin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NSP9-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSS3-1", "uniprot_id": [ { "id": "A0A1D5NSS3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSS3", "type": "external" } ], "mass": 74095.0, "length": 686, "protein_name": "PHD finger protein 21Aa", "gene_name": "phf21aa", "organism": "Zebrafish", "refseq_name": "PHD finger protein 21Aa isoform X1", "refseq_ac": [ { "id": "XP_009301632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301632", "type": "external" } ], "gene_names_uniprotkb": "phf21aa; im:7138823; si:dkey-23n7.9", "gene_names_refseq": "im:7138823; phf21aa; si:dkey-23n7.9", "protein_names_uniprotkb": "PHD finger protein 21Aa", "protein_names_refseq": "PHD finger protein 21Aa isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:497383); (R-DRE-3214815); (R-DRE-983231)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "23594743;24240475;26469318;30631305;33954026", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AUG0", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0000118 histone deacetylase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A1D5NSS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NSV4-1", "uniprot_id": [ { "id": "A0A1D5NSV4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NSV4", "type": "external" } ], "mass": 68147.0, "length": 593, "protein_name": "Crestin", "gene_name": "crestin", "organism": "Zebrafish", "refseq_name": "crestin", "refseq_ac": [ { "id": "NP_571068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571068", "type": "external" } ], "gene_names_uniprotkb": "crestin", "gene_names_refseq": "crestin", "protein_names_uniprotkb": "Crestin", "protein_names_refseq": "crestin; ctn", "tax_id": 7955, "disease": "", "pathway": " (dre:30186)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10660676;10683174;11543616;12538519;12952905;23594743;36477359;36582821;37107596;37489330;37746814", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: SRR26395062.1033331.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Mar 20, 2015 this sequence version replaced NP_571068.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PAC0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A1D5NSV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NT19-1", "uniprot_id": [ { "id": "A0A1D5NT19_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NT19", "type": "external" } ], "mass": 53463.0, "length": 487, "protein_name": "ACD shelterin complex subunit and telomerase recruitment factor; Adrenocortical dysplasia protein homolog isoform 1", "gene_name": "acd", "organism": "Zebrafish", "refseq_name": "adrenocortical dysplasia protein homolog isoform 1", "refseq_ac": [ { "id": "NP_001417988", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417988", "type": "external" } ], "gene_names_uniprotkb": "acd; tpp1; zgc:193816", "gene_names_refseq": "acd; tpp1; zgc:193816", "protein_names_uniprotkb": "ACD shelterin complex subunit and telomerase recruitment factor; Adrenocortical dysplasia protein homolog isoform 1", "protein_names_refseq": "adrenocortical dysplasia homolog; adrenocortical dysplasia protein homolog isoform 1; zfTPP1", "tax_id": 7955, "disease": "autosomal dominant dyskeratosis congenita 6 (Disease Ontology:DOID:0070023)", "pathway": " (dre:794664); (R-DRE-110330); (R-DRE-110331); (R-DRE-171319); (R-DRE-174430); (R-DRE-174437)", "pathway_count": 6, "publication_count": 8, "publication_id_list": "21311760;23594743;26469318;27189481;28448962;34214617;35150283;35667242", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.194211.1, SRR26395013.192203.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 21, 2024 this sequence version replaced XP_005168971.1., [RefSeq]; Knocking down TPP1 led to multiple abnormalities in zebrafish embryogenesis, including neural death, heart malformation, and caudal defect. Erratum:[PLoS One. 2011;6(2).doi: 10.1371/annotation/21d9bc69-ccac-49b8-82f2-a6303e93618a] Publication Status: Online-Only, [RefSeq, PubMed]; This work shows that the shelterin subunits exhibit distinct spatiotemporal expression patterns, suggesting important tissue-specific functions during development and aging, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG65", "ec_number_list": [], "go_molecular_function": "GO:0042162 telomeric DNA binding", "go_cellular_component": "GO:0070187 shelterin complex;GO:0005697 telomerase holoenzyme complex", "go_biological_process": "GO:0007507 heart development;GO:0043066 negative regulation of apoptotic process;GO:0016233 telomere capping;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0070198 protein localization to chromosome, telomeric region", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A1D5NT19-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NT24-1", "uniprot_id": [ { "id": "A0A1D5NT24_DANRE", "url": "https://www.uniprot.org/uniprot/A0A1D5NT24", "type": "external" } ], "mass": 85700.0, "length": 763, "protein_name": "Disintegrin and metalloproteinase domain-containing protein 10", "gene_name": "adam10a", "organism": "Zebrafish", "refseq_name": "disintegrin and metalloproteinase domain-containing protein 10 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001417916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417916", "type": "external" } ], "gene_names_uniprotkb": "adam10a; adam10; wu:fc03d12", "gene_names_refseq": "adam10a; adam10; wu:fc03d12", "protein_names_uniprotkb": "Disintegrin and metalloproteinase domain-containing protein 10; 3.4.24.81; Kuzbanian protein homolog", "protein_names_refseq": "a disintegrin and metalloprotease domain 10a; disintegrin and metalloproteinase domain-containing protein 10 isoform 1 precursor", "tax_id": 7955, "disease": "reticulate acropigmentation of Kitamura (Disease Ontology:DOID:0060258); Alzheimer's disease 18 (Disease Ontology:DOID:0110050); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dre:566044); (R-DRE-1474228); (R-DRE-381426); (R-DRE-6798695); (R-DRE-8957275)", "pathway_count": 5, "publication_count": 9, "publication_id_list": "17439641;19478994;23594743;26469318;27185351;28252024;28395729;31042481;33273096", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01009843.1, SRR26395017.1109887.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2025 this sequence version replaced NP_001417916.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG63", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "3.1.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.98", "type": "external" }, { "id": "1.14.14.18", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.18", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.4.21.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4", "type": "external" }, { "id": "3.4.21.112", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.112", "type": "external" }, { "id": "3.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.51", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" }, { "id": "3.4.21.69", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.69", "type": "external" } ], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0046872 metal ion binding;GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:0004222 metalloendopeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0097060 synaptic membrane;GO:0016020 membrane", "go_biological_process": "GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A1D5NT24-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NT51-1", "uniprot_id": [ { "id": "A0A1D5NT51_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NT51", "type": "external" } ], "mass": 8757.0, "length": 87, "protein_name": "CD24 molecule", "gene_name": "CD24", "organism": "Chicken", "refseq_name": "signal transducer CD24 precursor", "refseq_ac": [ { "id": "NP_001264664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264664", "type": "external" } ], "gene_names_uniprotkb": "CD24", "gene_names_refseq": "CD24", "protein_names_uniprotkb": "CD24 molecule", "protein_names_refseq": "signal transducer CD24 precursor", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01040326.1, SRR13267661.15681.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000065.1. On Sep 23, 2021 this sequence version replaced NP_001264664.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030296 protein tyrosine kinase activator activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0022407 regulation of cell-cell adhesion;GO:0001775 cell activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NT51-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NT61-1", "uniprot_id": [ { "id": "A0A1D5NT61_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NT61", "type": "external" } ], "mass": 60861.0, "length": 553, "protein_name": "Glutamate dehydrogenase 1, mitochondrial", "gene_name": "GLUD2", "organism": "Chicken", "refseq_name": "glutamate dehydrogenase 1, mitochondrial", "refseq_ac": [ { "id": "NP_001383395", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383395", "type": "external" } ], "gene_names_uniprotkb": "GLUD2", "gene_names_refseq": "GDH 1; GLUD1; GLUD2", "protein_names_uniprotkb": "Glutamate dehydrogenase 1, mitochondrial; 1.4.1.3", "protein_names_refseq": "GLUD2 glutamate; dehydrogenase 2; glutamate dehydrogenase 1, mitochondrial", "tax_id": 9031, "disease": "", "pathway": " (gga:423612); (R-GGA-2151201); (R-GGA-8964539); (R-GGA-9837999)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "23673664;23856561", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CR387697.1, MF415491.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992559 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1 and CR387697.1. On or before Oct 17, 2021 this sequence version replaced XP_015143519.1, XP_040530884.1., [RefSeq]; Analysis of the regulation and expression of chicken glutamate dehydrogenase reveals that it may regulate post-translational modifications of histone H3 by removing the N-terminal residues of the histone, [RefSeq, PubMed]; H3ase activity was only specific to chicken liver as it was not demonstrated in other tissues like heart, muscle and brain of chicken. We assign a novel serine like protease activity to GDH which is specific to histone H3., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "2.7.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.23", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "6.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.1", "type": "external" }, { "id": "6.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.17", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "5.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0004352 glutamate dehydrogenase (NAD+) activity;GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032024 positive regulation of insulin secretion;GO:0006541 glutamine metabolic process;GO:0006538 glutamate catabolic process;GO:0072350 tricarboxylic acid metabolic process;GO:0006520 amino acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NT61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NT70-1", "uniprot_id": [ { "id": "A0A1D5NT70_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NT70", "type": "external" } ], "mass": 25347.0, "length": 221, "protein_name": "glutathione transferase", "gene_name": "LOC395611", "organism": "Chicken", "refseq_name": "glutathione S-transferase isoform X2", "refseq_ac": [ { "id": "XP_015140398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140398", "type": "external" } ], "gene_names_uniprotkb": "LOC395611", "gene_names_refseq": "LOC395611", "protein_names_uniprotkb": "glutathione transferase; 2.5.1.18", "protein_names_refseq": "glutathione S-transferase isoform X2", "tax_id": 9031, "disease": "", "pathway": " (gga:395611); (R-GGA-156590); (R-GGA-9748787)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1D5NZK9", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NT70-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTF4-1", "uniprot_id": [ { "id": "A0A1D5NTF4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTF4", "type": "external" } ], "mass": 42165.0, "length": 376, "protein_name": "Protein Wnt", "gene_name": "WNT2", "organism": "Chicken", "refseq_name": "protein Wnt-2 isoform X1", "refseq_ac": [ { "id": "XP_416013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416013", "type": "external" } ], "gene_names_uniprotkb": "WNT2", "gene_names_refseq": "WNT2", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-2 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:417769); (R-GGA-3238698)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_416013.2. COMPLETENESS: full length., [RefSeq]; Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0005125 cytokine activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0071560 cellular response to transforming growth factor beta stimulus;GO:0048146 positive regulation of fibroblast proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTF4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTI9-1", "uniprot_id": [ { "id": "A0A1D5NTI9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTI9", "type": "external" } ], "mass": 10356.0, "length": 94, "protein_name": "PLAC 9", "gene_name": "PLAC9", "organism": "Chicken", "refseq_name": "placenta-specific protein 9 precursor", "refseq_ac": [ { "id": "NP_001289123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289123", "type": "external" } ], "gene_names_uniprotkb": "PLAC9", "gene_names_refseq": "PLAC9L; PLAC9", "protein_names_uniprotkb": "PLAC 9", "protein_names_refseq": "Placenta-specific 9-like; placenta specific 9; placenta-specific protein 9 precursor; placenta-specific protein 9", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BU404696.1, BX258920.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1. On Sep 23, 2021 this sequence version replaced NP_001289123.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTI9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTJ0-1", "uniprot_id": [ { "id": "A0A1D5NTJ0_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTJ0", "type": "external" } ], "mass": 76203.0, "length": 666, "protein_name": "Frizzled-3", "gene_name": "FZD3", "organism": "Chicken", "refseq_name": "frizzled-3 precursor", "refseq_ac": [ { "id": "NP_001258869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258869", "type": "external" } ], "gene_names_uniprotkb": "FZD3", "gene_names_refseq": "FZ-3; FZD3", "protein_names_uniprotkb": "Frizzled-3", "protein_names_refseq": "frizzled family receptor 3; frizzled homolog 3; frizzled-3 precursor; frizzled-3", "tax_id": 9031, "disease": "", "pathway": " (gga:395572); (R-GGA-4086398); (R-GGA-4608870)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0030165 PDZ domain binding;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0048787 presynaptic active zone membrane;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0097475 motor neuron migration;GO:0042472 inner ear morphogenesis;GO:0001843 neural tube closure;GO:0060070 canonical Wnt signaling pathway;GO:0060071 Wnt signaling pathway, planar cell polarity pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTJ0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTJ6-1", "uniprot_id": [ { "id": "A0A1D5NTJ6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTJ6", "type": "external" } ], "mass": 71702.0, "length": 640, "protein_name": "Uncharacterized protein", "gene_name": "LOC426615", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC426615", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTJ6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTP6-1", "uniprot_id": [ { "id": "A0A1D5NTP6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTP6", "type": "external" } ], "mass": 137202.0, "length": 1245, "protein_name": "Protocadherin 11 X-linked", "gene_name": "PCDH11X", "organism": "Chicken", "refseq_name": "protocadherin-11 X-linked isoform X4", "refseq_ac": [ { "id": "XP_040527821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527821", "type": "external" } ], "gene_names_uniprotkb": "PCDH11X", "gene_names_refseq": "PCDH11X", "protein_names_uniprotkb": "Protocadherin 11 X-linked", "protein_names_refseq": "protocadherin-11 X-linked isoform X4", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Potential calcium-dependent cell-adhesion protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTP6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTR1-1", "uniprot_id": [ { "id": "A0A1D5NTR1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTR1", "type": "external" } ], "mass": 53298.0, "length": 478, "protein_name": "Coiled-coil domain containing 6", "gene_name": "CCDC6", "organism": "Chicken", "refseq_name": "coiled-coil domain-containing protein 6", "refseq_ac": [ { "id": "NP_001026392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026392", "type": "external" } ], "gene_names_uniprotkb": "CCDC6", "gene_names_refseq": "CCDC6", "protein_names_uniprotkb": "Coiled-coil domain containing 6", "protein_names_refseq": "coiled-coil domain-containing protein 6", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ851457.1, HAEK01051086.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000227.1. On Sep 23, 2021 this sequence version replaced NP_001026392.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTR1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTS2-1", "uniprot_id": [ { "id": "A0A1D5NTS2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTS2", "type": "external" } ], "mass": 29723.0, "length": 262, "protein_name": "Carbonic anhydrase", "gene_name": "CA3A", "organism": "Chicken", "refseq_name": "carbonic anhydrase 3A", "refseq_ac": [ { "id": "NP_001264340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264340", "type": "external" } ], "gene_names_uniprotkb": "CA3A", "gene_names_refseq": "CA3A; CA3", "protein_names_uniprotkb": "Carbonic anhydrase; 4.2.1.1", "protein_names_refseq": "carbonic anhydrase 3A; carbonic anhydrase III, muscle specific", "tax_id": 9031, "disease": "", "pathway": " (gga:420208)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BU437187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000044.1. On Apr 6, 2013 this sequence version replaced XP_418319.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Reversible hydration of carbon dioxide., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1", "type": "external" }, { "id": "4.2.1.69", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.69", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTS2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTV7-1", "uniprot_id": [ { "id": "A0A1D5NTV7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTV7", "type": "external" } ], "mass": 49873.0, "length": 438, "protein_name": "Zinc finger and BTB domain containing 26", "gene_name": "ZBTB26", "organism": "Chicken", "refseq_name": "zinc finger and BTB domain-containing protein 26", "refseq_ac": [ { "id": "NP_001264568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264568", "type": "external" } ], "gene_names_uniprotkb": "ZBTB26", "gene_names_refseq": "ZBTB26", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 26", "protein_names_refseq": "zinc finger and BTB domain-containing protein 26", "tax_id": 9031, "disease": "", "pathway": " (gga:417107)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267656.9375.1, SRR13267661.10171.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Apr 13, 2013 this sequence version replaced XP_003642347.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTV7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTX3-1", "uniprot_id": [ { "id": "A0A1D5NTX3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTX3", "type": "external" } ], "mass": 23329.0, "length": 208, "protein_name": "ADP-ribosylation factor-like 8B-like", "gene_name": "ARL8BL", "organism": "Chicken", "refseq_name": "ADP-ribosylation factor-like 8B-like isoform X1", "refseq_ac": [ { "id": "XP_015137488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137488", "type": "external" } ], "gene_names_uniprotkb": "ARL8BL; RCJMB04_11g18", "gene_names_refseq": "ARL8BL", "protein_names_uniprotkb": "ADP-ribosylation factor-like 8B-like", "protein_names_refseq": "ADP-ribosylation factor-like 8B-like isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:769134)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15642098", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0015031 protein transport;GO:0051301 cell division;GO:0008089 anterograde axonal transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NTX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTY5-1", "uniprot_id": [ { "id": "A0A1D5NTY5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTY5", "type": "external" } ], "mass": 89311.0, "length": 806, "protein_name": "Transitional endoplasmic reticulum ATPase", "gene_name": "LOC430766", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC430766", "gene_names_refseq": "", "protein_names_uniprotkb": "Transitional endoplasmic reticulum ATPase; 3.6.4.6; Valosin-containing protein", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008289 lipid binding;GO:0031593 polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006914 autophagy;GO:0097352 autophagosome maturation;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051228 mitotic spindle disassembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTY5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTY7-1", "uniprot_id": [ { "id": "A0A1D5NTY7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTY7", "type": "external" } ], "mass": 43854.0, "length": 380, "protein_name": "Fibromodulin", "gene_name": "FMOD", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FMOD", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibromodulin; Keratan sulfate proteoglycan fibromodulin", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-2022854); (R-GGA-2022857); (R-GGA-6794361)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTY7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NTY9-1", "uniprot_id": [ { "id": "A0A1D5NTY9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NTY9", "type": "external" } ], "mass": 55743.0, "length": 479, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "AKT3", "organism": "Chicken", "refseq_name": "RAC-gamma serine/threonine-protein kinase isoform X1", "refseq_ac": [ { "id": "XP_015139467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139467", "type": "external" } ], "gene_names_uniprotkb": "AKT3", "gene_names_refseq": "AKT3", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "RAC-gamma serine/threonine-protein kinase isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:421497)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1L1RUI3", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:0007165 signal transduction;GO:0045766 positive regulation of angiogenesis;GO:0048873 homeostasis of number of cells within a tissue;GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NTY9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NU20-1", "uniprot_id": [ { "id": "A0A1D5NU20_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NU20", "type": "external" } ], "mass": 74150.0, "length": 671, "protein_name": "Potassium calcium-activated channel subfamily N member 3", "gene_name": "KCNN3", "organism": "Chicken", "refseq_name": "small conductance calcium-activated potassium channel protein 3 isoform X1", "refseq_ac": [ { "id": "XP_015153999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153999", "type": "external" } ], "gene_names_uniprotkb": "KCNN3", "gene_names_refseq": "KCNN3", "protein_names_uniprotkb": "Potassium calcium-activated channel subfamily N member 3", "protein_names_refseq": "small conductance calcium-activated potassium channel protein 3 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:100858107); (R-GGA-1296052)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0016286 small conductance calcium-activated potassium channel activity;GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043025 neuronal cell body;GO:0043005 neuron projection;GO:0030018 Z disc", "go_biological_process": "GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NU20-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NU41-1", "uniprot_id": [ { "id": "A0A1D5NU41_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NU41", "type": "external" } ], "mass": 69144.0, "length": 599, "protein_name": "Glycerophosphodiester phosphodiesterase domain containing 5", "gene_name": "GDPD5", "organism": "Chicken", "refseq_name": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "refseq_ac": [ { "id": "XP_015136462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462", "type": "external" } ], "gene_names_uniprotkb": "GDPD5", "gene_names_refseq": "GDE2; GDPD5", "protein_names_uniprotkb": "Glycerophosphodiester phosphodiesterase domain containing 5", "protein_names_refseq": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008889 glycerophosphodiester phosphodiesterase activity;GO:0008081 phosphoric diester hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0016020 membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0045666 positive regulation of neuron differentiation;GO:0045597 positive regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NU41-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NU45-1", "uniprot_id": [ { "id": "A0A1D5NU45_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NU45", "type": "external" } ], "mass": 28658.0, "length": 267, "protein_name": "Chymotrypsin C", "gene_name": "CTRC", "organism": "Chicken", "refseq_name": "chymotrypsin-C precursor", "refseq_ac": [ { "id": "NP_001264846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846", "type": "external" } ], "gene_names_uniprotkb": "CTRC", "gene_names_refseq": "CTRC", "protein_names_uniprotkb": "Chymotrypsin C", "protein_names_refseq": "chymotrypsin C (caldecrin); chymotrypsin-C precursor", "tax_id": 9031, "disease": "", "pathway": " (gga:430670)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BX935336.1, CR338978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992482, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000329.1. On Apr 28, 2013 this sequence version replaced XP_428223.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0006874 intracellular calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NU45-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NU91-1", "uniprot_id": [ { "id": "A0A1D5NU91_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NU91", "type": "external" } ], "mass": 87607.0, "length": 787, "protein_name": "Solute carrier family 45 member 4", "gene_name": "SLC45A4", "organism": "Chicken", "refseq_name": "solute carrier family 45 member 4", "refseq_ac": [ { "id": "XP_015138722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138722", "type": "external" } ], "gene_names_uniprotkb": "SLC45A4", "gene_names_refseq": "SLC45A4", "protein_names_uniprotkb": "Solute carrier family 45 member 4", "protein_names_refseq": "solute carrier family 45 member 4", "tax_id": 9031, "disease": "", "pathway": " (gga:420308)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proton-associated sucrose transporter. May be able to transport also glucose and fructose., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008506 sucrose:proton symporter activity;GO:0005351 carbohydrate:proton symporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NU91-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NU93-1", "uniprot_id": [ { "id": "A0A1D5NU93_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NU93", "type": "external" } ], "mass": 69144.0, "length": 605, "protein_name": "mRNA-capping enzyme", "gene_name": "RNGTT", "organism": "Chicken", "refseq_name": "mRNA-capping enzyme isoform X1", "refseq_ac": [ { "id": "XP_040522647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040522647", "type": "external" } ], "gene_names_uniprotkb": "RNGTT", "gene_names_refseq": "RNGTT", "protein_names_uniprotkb": "mRNA-capping enzyme; GTP--RNA guanylyltransferase; GTase; mRNA 5'-phosphatase", "protein_names_refseq": "mRNA-capping enzyme isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:421819); (R-GGA-72086); (R-GGA-77075)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.50", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.50", "type": "external" }, { "id": "3.6.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.74", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004721 phosphoprotein phosphatase activity;GO:0004651 polynucleotide 5'-phosphatase activity;GO:0004484 mRNA guanylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006370 7-methylguanosine mRNA capping", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NU93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUC6-1", "uniprot_id": [ { "id": "A0A1D5NUC6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUC6", "type": "external" } ], "mass": 20414.0, "length": 179, "protein_name": "Mediator of RNA polymerase II transcription subunit 30", "gene_name": "MED30", "organism": "Chicken", "refseq_name": "mediator of RNA polymerase II transcription subunit 30", "refseq_ac": [ { "id": "NP_001264365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264365", "type": "external" } ], "gene_names_uniprotkb": "MED30", "gene_names_refseq": "MED30; THRAP6", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 30; Mediator complex subunit 30", "protein_names_refseq": "mediator of RNA polymerase II transcription subunit 30; thyroid hormone receptor associated protein 6", "tax_id": 9031, "disease": "", "pathway": " (gga:420284); (R-GGA-9841922)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BX932068.1, HAEK01132315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On or before Apr 7, 2013 this sequence version replaced XP_418397.1, XP_001232202.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0046966 nuclear thyroid hormone receptor binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0035019 somatic stem cell population maintenance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUC6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUD1-1", "uniprot_id": [ { "id": "A0A1D5NUD1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUD1", "type": "external" } ], "mass": 58810.0, "length": 530, "protein_name": "BTB domain containing 6", "gene_name": "BTBD6", "organism": "Chicken", "refseq_name": "BTB/POZ domain-containing protein 6 isoform X1", "refseq_ac": [ { "id": "XP_004936479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936479", "type": "external" } ], "gene_names_uniprotkb": "BTBD6", "gene_names_refseq": "BTBD6", "protein_names_uniprotkb": "BTB domain containing 6", "protein_names_refseq": "BTB/POZ domain-containing protein 6 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:101752037); (R-GGA-8951664); (R-GGA-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUD1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUG1-1", "uniprot_id": [ { "id": "A0A1D5NUG1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUG1", "type": "external" } ], "mass": 19031.0, "length": 167, "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "CGGBP1", "organism": "Chicken", "refseq_name": "CGG triplet repeat-binding protein 1", "refseq_ac": [ { "id": "XP_004938360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938360", "type": "external" } ], "gene_names_uniprotkb": "CGGBP1", "gene_names_refseq": "CGGBP1", "protein_names_uniprotkb": "CGG triplet repeat binding protein 1", "protein_names_refseq": "CGG triplet repeat-binding protein 1", "tax_id": 9031, "disease": "", "pathway": " (gga:770224)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004938360.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0042802 identical protein binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010468 regulation of gene expression;GO:0040029 epigenetic regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUG1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUH1-1", "uniprot_id": [ { "id": "A0A1D5NUH1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUH1", "type": "external" } ], "mass": 32353.0, "length": 289, "protein_name": "Thioredoxin-like protein 1", "gene_name": "TXNL1", "organism": "Chicken", "refseq_name": "thioredoxin-like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_424463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424463", "type": "external" } ], "gene_names_uniprotkb": "TXNL1", "gene_names_refseq": "TXNL1", "protein_names_uniprotkb": "Thioredoxin-like protein 1", "protein_names_refseq": "thioredoxin-like protein 1 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:426854); (R-GGA-9013418); (R-GGA-9013420); (R-GGA-9013422); (R-GGA-9013424); (R-GGA-9696264); (R-GGA-9696270)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Active thioredoxin with a redox potential of about -250 mV., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUH1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUH3-1", "uniprot_id": [ { "id": "A0A1D5NUH3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUH3", "type": "external" } ], "mass": 52320.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC769000", "organism": "Chicken", "refseq_name": "mothers against decapentaplegic homolog 2 isoform X1", "refseq_ac": [ { "id": "XP_001232181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232181", "type": "external" } ], "gene_names_uniprotkb": "LOC769000", "gene_names_refseq": "LOC769000", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 2 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:769000); (R-GGA-1181150); (R-GGA-1502540); (R-GGA-2173788); (R-GGA-2173789); (R-GGA-2173795); (R-GGA-2173796); (R-GGA-5689880); (R-GGA-9617828)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001232181.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0005634 nucleus", "go_biological_process": "GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUH3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUJ8-1", "uniprot_id": [ { "id": "A0A1D5NUJ8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUJ8", "type": "external" } ], "mass": 33960.0, "length": 312, "protein_name": "Ubiquitin-conjugating enzyme E2Q-like protein 1", "gene_name": "UBE2QL1", "organism": "Chicken", "refseq_name": "ubiquitin-conjugating enzyme E2Q-like protein 1", "refseq_ac": [ { "id": "XP_040519022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519022", "type": "external" } ], "gene_names_uniprotkb": "UBE2QL1", "gene_names_refseq": "UBE2QL1", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2Q-like protein 1; 2.3.2.23; E2Q-like ubiquitin-conjugating enzyme 1", "protein_names_refseq": "ubiquitin-conjugating enzyme E2Q-like protein 1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUJ8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUL1-1", "uniprot_id": [ { "id": "A0A1D5NUL1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUL1", "type": "external" } ], "mass": 145714.0, "length": 1270, "protein_name": "DENN domain-containing protein 3", "gene_name": "DENND3", "organism": "Chicken", "refseq_name": "DENN domain-containing protein 3", "refseq_ac": [ { "id": "XP_418419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418419", "type": "external" } ], "gene_names_uniprotkb": "DENND3", "gene_names_refseq": "DENND3", "protein_names_uniprotkb": "DENN domain-containing protein 3", "protein_names_refseq": "DENN domain-containing protein 3", "tax_id": 9031, "disease": "", "pathway": " (gga:420309); (R-GGA-8876198)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418419.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0005737 cytoplasm", "go_biological_process": "GO:0032483 regulation of Rab protein signal transduction;GO:0008333 endosome to lysosome transport;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUL1-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUM3-1", "uniprot_id": [ { "id": "A0A1D5NUM3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUM3", "type": "external" } ], "mass": 13123.0, "length": 122, "protein_name": "Mth938 domain-containing protein", "gene_name": "AAMDC", "organism": "Chicken", "refseq_name": "mth938 domain-containing protein", "refseq_ac": [ { "id": "NP_001265029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029", "type": "external" } ], "gene_names_uniprotkb": "AAMDC", "gene_names_refseq": "AAMDC; C11orf6; C1H11ORF67; CK067; PTD015", "protein_names_uniprotkb": "Mth938 domain-containing protein", "protein_names_refseq": "UPF0366 protein C11orf67; adipogenesis associated Mth938 domain-containing protein; mth938 domain-containing protein", "tax_id": 9031, "disease": "", "pathway": " (gga:425610)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BX930541.1, HAEL01011812.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000028.1. On or before May 10, 2013 this sequence version replaced XP_003640647.1, XP_003640648.1, XP_424622.1. Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045600 positive regulation of fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUM3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUM5-1", "uniprot_id": [ { "id": "A0A1D5NUM5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUM5", "type": "external" } ], "mass": 47065.0, "length": 418, "protein_name": "AP-3 complex subunit mu-2", "gene_name": "AP3M2", "organism": "Chicken", "refseq_name": "AP-3 complex subunit mu-2 isoform X2", "refseq_ac": [ { "id": "XP_424403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424403", "type": "external" } ], "gene_names_uniprotkb": "AP3M2", "gene_names_refseq": "AP3M2", "protein_names_uniprotkb": "AP-3 complex subunit mu-2", "protein_names_refseq": "AP-3 complex subunit mu-2 isoform X2", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_424403.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005794 Golgi apparatus;GO:0030659 cytoplasmic vesicle membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0048490 anterograde synaptic vesicle transport;GO:0048488 synaptic vesicle endocytosis;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUM5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUP4-1", "uniprot_id": [ { "id": "A0A1D5NUP4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUP4", "type": "external" } ], "mass": 44996.0, "length": 398, "protein_name": "WD repeat domain 86", "gene_name": "WDR86", "organism": "Chicken", "refseq_name": "WD repeat-containing protein 86 isoform X1", "refseq_ac": [ { "id": "XP_001233535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233535", "type": "external" } ], "gene_names_uniprotkb": "WDR86", "gene_names_refseq": "WDR86", "protein_names_uniprotkb": "WD repeat domain 86", "protein_names_refseq": "WD repeat-containing protein 86 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:770203)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233535.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUP4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUQ3-1", "uniprot_id": [ { "id": "A0A1D5NUQ3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUQ3", "type": "external" } ], "mass": 31121.0, "length": 273, "protein_name": "SplA/ryanodine receptor domain and SOCS box containing 4", "gene_name": "SPSB4", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SPSB4", "gene_names_refseq": "", "protein_names_uniprotkb": "SplA/ryanodine receptor domain and SOCS box containing 4", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-8951664); (R-GGA-983168)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0019005 SCF ubiquitin ligase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0042752 regulation of circadian rhythm;GO:1902916 positive regulation of protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUQ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUT3-1", "uniprot_id": [ { "id": "A0A1D5NUT3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUT3", "type": "external" } ], "mass": 34411.0, "length": 298, "protein_name": "Fibrinogen silencer binding protein", "gene_name": "FSBP", "organism": "Chicken", "refseq_name": "fibrinogen silencer-binding protein", "refseq_ac": [ { "id": "XP_001233122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233122", "type": "external" } ], "gene_names_uniprotkb": "FSBP", "gene_names_refseq": "FSBP", "protein_names_uniprotkb": "Fibrinogen silencer binding protein", "protein_names_refseq": "fibrinogen silencer-binding protein", "tax_id": 9031, "disease": "", "pathway": " (gga:770634)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUT3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUT5-1", "uniprot_id": [ { "id": "A0A1D5NUT5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUT5", "type": "external" } ], "mass": 41511.0, "length": 379, "protein_name": "Nuclear receptor subfamily 2 group F member 6", "gene_name": "NR2F6", "organism": "Chicken", "refseq_name": "nuclear receptor subfamily 2 group F member 6 isoform X2", "refseq_ac": [ { "id": "XP_015155582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155582", "type": "external" } ], "gene_names_uniprotkb": "NR2F6", "gene_names_refseq": "NR2F6", "protein_names_uniprotkb": "Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2", "protein_names_refseq": "nuclear receptor subfamily 2 group F member 6 isoform X2", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-383280)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015155582.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0050965 detection of temperature stimulus involved in sensory perception of pain;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUT5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NUY6-1", "uniprot_id": [ { "id": "A0A1D5NUY6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NUY6", "type": "external" } ], "mass": 12774.0, "length": 110, "protein_name": "NADH dehydrogenase [ubiquinone] 1 subunit C2", "gene_name": "NDUFC2", "organism": "Chicken", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 1", "refseq_ac": [ { "id": "NP_001383923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383923", "type": "external" } ], "gene_names_uniprotkb": "NDUFC2", "gene_names_refseq": "NDUFC2", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 subunit C2", "protein_names_refseq": "NADH dehydrogenase B14.5b; NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 1; NADH dehydrogenase [ubiquinone] 1 subunit C2; NADH:ubiquinone oxidoreductase subunit C2", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-611105); (R-GGA-6798695); (R-GGA-6799198)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HAEL01014354.1, HAEK01012600.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000028.1., [RefSeq]; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0006120 mitochondrial electron transport, NADH to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NUY6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NV13-1", "uniprot_id": [ { "id": "A0A1D5NV13_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NV13", "type": "external" } ], "mass": 24886.0, "length": 217, "protein_name": "small monomeric GTPase", "gene_name": "RIT2", "organism": "Chicken", "refseq_name": "GTP-binding protein Rit2 isoform X1", "refseq_ac": [ { "id": "XP_001233997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233997", "type": "external" } ], "gene_names_uniprotkb": "RIT2", "gene_names_refseq": "RIT2", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "GTP-binding protein Rit2 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:770660)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233997.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003682 chromatin binding;GO:0005516 calmodulin binding;GO:0030215 semaphorin receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0097447 dendritic tree;GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0032507 maintenance of protein location in cell;GO:0010976 positive regulation of neuron projection development;GO:0030100 regulation of endocytosis;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NV13-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NV17-1", "uniprot_id": [ { "id": "A0A1D5NV17_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NV17", "type": "external" } ], "mass": 42014.0, "length": 377, "protein_name": "Actin beta like 2", "gene_name": "ACTBL2", "organism": "Chicken", "refseq_name": "actin, alpha skeletal muscle B", "refseq_ac": [ { "id": "XP_424279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424279", "type": "external" } ], "gene_names_uniprotkb": "ACTBL2", "gene_names_refseq": "ACTBL2", "protein_names_uniprotkb": "Actin beta like 2", "protein_names_refseq": "actin, alpha skeletal muscle B", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NV17-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NV46-1", "uniprot_id": [ { "id": "A0A1D5NV46_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NV46", "type": "external" } ], "mass": 61604.0, "length": 561, "protein_name": "glycerol kinase", "gene_name": "GK2", "organism": "Chicken", "refseq_name": "glycerol kinase isoform X1", "refseq_ac": [ { "id": "XP_003640559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640559", "type": "external" } ], "gene_names_uniprotkb": "GK2", "gene_names_refseq": "GK2", "protein_names_uniprotkb": "glycerol kinase; 2.7.1.30; ATP:glycerol 3-phosphotransferase", "protein_names_refseq": "glycerol kinase isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:418589); (R-GGA-75109)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003640559.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.30", "type": "external" } ], "go_molecular_function": "GO:0004370 glycerol kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0006071 glycerol metabolic process;GO:0006072 glycerol-3-phosphate metabolic process;GO:0046167 glycerol-3-phosphate biosynthetic process;GO:0006641 triglyceride metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NV46-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NV75-1", "uniprot_id": [ { "id": "A0A1D5NV75_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NV75", "type": "external" } ], "mass": 33245.0, "length": 295, "protein_name": "NSF attachment protein alpha", "gene_name": "NAPA", "organism": "Chicken", "refseq_name": "alpha-soluble NSF attachment protein", "refseq_ac": [ { "id": "XP_015127972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127972", "type": "external" } ], "gene_names_uniprotkb": "NAPA", "gene_names_refseq": "NAPA", "protein_names_uniprotkb": "NSF attachment protein alpha", "protein_names_refseq": "alpha-soluble NSF attachment protein", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-6807878); (R-GGA-6811434); (R-GGA-6811438); (R-GGA-6811440)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052569.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015127972.1. COMPLETENESS: full length., [RefSeq]; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0005483 soluble NSF attachment protein activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098793 presynapse;GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0016020 membrane", "go_biological_process": "GO:0035494 SNARE complex disassembly;GO:0006886 intracellular protein transport;GO:0035249 synaptic transmission, glutamatergic;GO:0007420 brain development;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NV75-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NV88-1", "uniprot_id": [ { "id": "A0A1D5NV88_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NV88", "type": "external" } ], "mass": 66970.0, "length": 579, "protein_name": "FERM domain-containing protein 3", "gene_name": "FRMD3", "organism": "Chicken", "refseq_name": "FERM domain-containing protein 3 isoform X3", "refseq_ac": [ { "id": "XP_003643086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643086", "type": "external" } ], "gene_names_uniprotkb": "FRMD3", "gene_names_refseq": "FRMD3", "protein_names_uniprotkb": "FERM domain-containing protein 3", "protein_names_refseq": "FERM domain-containing protein 3 isoform X3", "tax_id": 9031, "disease": "", "pathway": " (gga:427452)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008092 cytoskeletal protein binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NV88-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVE2-1", "uniprot_id": [ { "id": "A0A1D5NVE2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVE2", "type": "external" } ], "mass": 44988.0, "length": 408, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "UBE2Q1", "organism": "Chicken", "refseq_name": "ubiquitin-conjugating enzyme E2 Q1", "refseq_ac": [ { "id": "XP_024999232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999232", "type": "external" } ], "gene_names_uniprotkb": "UBE2Q1", "gene_names_refseq": "UBE2Q1", "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 2.3.2.23", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 Q1", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-983168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "6.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" } ], "go_molecular_function": "GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007617 mating behavior;GO:0009566 fertilization;GO:0000209 protein polyubiquitination;GO:0070459 prolactin secretion;GO:0061458 reproductive system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVE2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVI1-1", "uniprot_id": [ { "id": "A0A1D5NVI1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVI1", "type": "external" } ], "mass": 21835.0, "length": 192, "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "RPL9", "organism": "Chicken", "refseq_name": "large ribosomal subunit protein uL6", "refseq_ac": [ { "id": "NP_001244262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244262", "type": "external" } ], "gene_names_uniprotkb": "RPL9", "gene_names_refseq": "RPL9", "protein_names_uniprotkb": "Large ribosomal subunit protein uL6; 60S ribosomal protein L9", "protein_names_refseq": "large ribosomal subunit protein uL6", "tax_id": 9031, "disease": "", "pathway": " (gga:425468); (R-GGA-1799339); (R-GGA-72706); (R-GGA-975956); (R-GGA-975957); (R-GGA-9954709); (R-GGA-9954714); (R-GGA-9954716)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "16879355;38395592", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CF251699.1, BU144270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On Mar 31, 2012 this sequence version replaced XP_003641294.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NVI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVI6-1", "uniprot_id": [ { "id": "A0A1D5NVI6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVI6", "type": "external" } ], "mass": 88435.0, "length": 766, "protein_name": "BMP/retinoic acid inducible neural specific 3", "gene_name": "BRINP3", "organism": "Chicken", "refseq_name": "BMP/retinoic acid-inducible neural-specific protein 3 isoform X1", "refseq_ac": [ { "id": "XP_004943345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943345", "type": "external" } ], "gene_names_uniprotkb": "BRINP3", "gene_names_refseq": "BRINP3", "protein_names_uniprotkb": "BMP/retinoic acid inducible neural specific 3", "protein_names_refseq": "BMP/retinoic acid-inducible neural-specific protein 3 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:429077)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0045666 positive regulation of neuron differentiation;GO:0071300 cellular response to retinoic acid;GO:0035640 exploration behavior;GO:0035264 multicellular organism growth;GO:0045930 negative regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVI6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVK1-1", "uniprot_id": [ { "id": "A0A1D5NVK1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVK1", "type": "external" } ], "mass": 34910.0, "length": 305, "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC7", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ZDHHC7", "gene_names_refseq": "", "protein_names_uniprotkb": "Palmitoyltransferase; 2.3.1.225", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-9009391)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0006612 protein targeting to membrane;GO:0030521 androgen receptor signaling pathway;GO:1903076 regulation of protein localization to plasma membrane;GO:0044381 glucose import in response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVK1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVK9-1", "uniprot_id": [ { "id": "A0A1D5NVK9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVK9", "type": "external" } ], "mass": 40775.0, "length": 350, "protein_name": "Neutrophil cytosol factor 4", "gene_name": "NCF4", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NCF4", "gene_names_refseq": "", "protein_names_uniprotkb": "Neutrophil cytosol factor 4; Neutrophil NADPH oxidase factor 4; p40-phox", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-1222556); (R-GGA-1236973); (R-GGA-3299685); (R-GGA-4420097); (R-GGA-5668599); (R-GGA-9013149); (R-GGA-9013404); (R-GGA-9013423)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0016176 superoxide-generating NADPH oxidase activator activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010008 endosome membrane", "go_biological_process": "GO:0006909 phagocytosis;GO:0045730 respiratory burst;GO:0042554 superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVK9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVP7-1", "uniprot_id": [ { "id": "A0A1D5NVP7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVP7", "type": "external" } ], "mass": 6578.0, "length": 61, "protein_name": "Energy homeostasis associated", "gene_name": "ENHO", "organism": "Chicken", "refseq_name": "adropin", "refseq_ac": [ { "id": "NP_001289120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289120", "type": "external" } ], "gene_names_uniprotkb": "ENHO", "gene_names_refseq": "ENHO", "protein_names_uniprotkb": "Energy homeostasis associated", "protein_names_refseq": "adropin", "tax_id": 9031, "disease": "", "pathway": " (gga:768968)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: BX932108.2 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX932108.2. On Oct 4, 2014 this sequence version replaced XP_001231843.3., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVP7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVP9-1", "uniprot_id": [ { "id": "A0A1D5NVP9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVP9", "type": "external" } ], "mass": 104630.0, "length": 940, "protein_name": "FYVE, RhoGEF and PH domain containing 3", "gene_name": "FGD3", "organism": "Chicken", "refseq_name": "FYVE, RhoGEF and PH domain-containing protein 3 isoform X2", "refseq_ac": [ { "id": "XP_414331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414331", "type": "external" } ], "gene_names_uniprotkb": "FGD3", "gene_names_refseq": "FGD3", "protein_names_uniprotkb": "FYVE, RhoGEF and PH domain containing 3", "protein_names_refseq": "FYVE, RhoGEF and PH domain-containing protein 3 isoform X2", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-193648); (R-GGA-416482); (R-GGA-9013148)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_414331.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0046847 filopodium assembly;GO:0007010 cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVP9-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVQ9-1", "uniprot_id": [ { "id": "A0A1D5NVQ9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVQ9", "type": "external" } ], "mass": 58074.0, "length": 517, "protein_name": "Gamma-1-syntrophin", "gene_name": "SNTG1", "organism": "Chicken", "refseq_name": "gamma-1-syntrophin isoform X1", "refseq_ac": [ { "id": "XP_004939906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939906", "type": "external" } ], "gene_names_uniprotkb": "SNTG1", "gene_names_refseq": "SNTG1", "protein_names_uniprotkb": "Gamma-1-syntrophin; Syntrophin-4", "protein_names_refseq": "gamma-1-syntrophin isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:421113)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016010 dystrophin-associated glycoprotein complex;GO:0005634 nucleus;GO:0032587 ruffle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVQ9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVR2-1", "uniprot_id": [ { "id": "A0A1D5NVR2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVR2", "type": "external" } ], "mass": 72913.0, "length": 646, "protein_name": "Growth hormone receptor", "gene_name": "GHR", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GHR", "gene_names_refseq": "", "protein_names_uniprotkb": "Growth hormone receptor; Somatotropin receptor", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-1170546); (R-GGA-512988); (R-GGA-5673001); (R-GGA-912526); (R-GGA-982772)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0017046 peptide hormone binding;GO:0019955 cytokine binding;GO:0004903 growth hormone receptor activity;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0009897 external side of plasma membrane;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0070195 growth hormone receptor complex", "go_biological_process": "GO:0006897 endocytosis;GO:0008284 positive regulation of cell population proliferation;GO:0042445 hormone metabolic process;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0048009 insulin-like growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVR2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVS3-1", "uniprot_id": [ { "id": "A0A1D5NVS3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVS3", "type": "external" } ], "mass": 23675.0, "length": 199, "protein_name": "Dermatopontin", "gene_name": "DPT", "organism": "Chicken", "refseq_name": "dermatopontin", "refseq_ac": [ { "id": "XP_001231676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231676", "type": "external" } ], "gene_names_uniprotkb": "DPT", "gene_names_refseq": "DPT", "protein_names_uniprotkb": "Dermatopontin", "protein_names_refseq": "dermatopontin", "tax_id": 9031, "disease": "", "pathway": " (gga:768904)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001231676.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVS3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVS8-1", "uniprot_id": [ { "id": "MSL2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVS8", "type": "external" } ], "mass": 62252.0, "length": 579, "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "MSL2", "organism": "Chicken", "refseq_name": "E3 ubiquitin-protein ligase MSL2 isoform X1", "refseq_ac": [ { "id": "XP_426675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426675", "type": "external" } ], "gene_names_uniprotkb": "MSL2", "gene_names_refseq": "MSL2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MSL2; 2.3.2.27; MSL-2; Male-specific lethal-2 homolog", "protein_names_refseq": "E3 ubiquitin-protein ligase MSL2 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-3214847)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15592404;23874665", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426675.1. COMPLETENESS: full length., [RefSeq]; Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction (By similarity). The MSL complex is required for chromosome stability and genome integrity by maintaining homeostatic levels of H4K16ac (By similarity). MSL2 plays a key role in gene dosage by ensuring biallelic expression of a subset of dosage-sensitive genes, including many haploinsufficient genes (By similarity). Acts by promoting promoter-enhancer contacts, thereby preventing DNA methylation of one allele and creating a methylation-free environment for methylation-sensitive transcription factors such as SP1, KANSL1 and KANSL3 (By similarity). Also acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A (By similarity). Also involved in the DNA damage response by mediating ubiquitination of TP53/p53 and TP53BP1 (PubMed:23874665)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0140585 promoter-enhancer loop anchoring activity;GO:0141054 histone H2B ubiquitin ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0072487 MSL complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0045893 positive regulation of DNA-templated transcription;GO:0016567 protein ubiquitination;GO:0040029 epigenetic regulation of gene expression;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NVS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVT2-1", "uniprot_id": [ { "id": "A0A1D5NVT2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVT2", "type": "external" } ], "mass": 47987.0, "length": 427, "protein_name": "Sulfotransferase", "gene_name": "CHST2", "organism": "Chicken", "refseq_name": "carbohydrate sulfotransferase 2", "refseq_ac": [ { "id": "XP_040535583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535583", "type": "external" } ], "gene_names_uniprotkb": "CHST2", "gene_names_refseq": "CHST2", "protein_names_uniprotkb": "Sulfotransferase; 2.8.2.-", "protein_names_refseq": "carbohydrate sulfotransferase 2", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-2022854)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052581.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040535583.1. COMPLETENESS: full length., [RefSeq]; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.-", "type": "external" } ], "go_molecular_function": "GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006044 N-acetylglucosamine metabolic process;GO:1903238 positive regulation of leukocyte tethering or rolling;GO:0006954 inflammatory response;GO:0005975 carbohydrate metabolic process;GO:0006790 sulfur compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVT2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NVV7-1", "uniprot_id": [ { "id": "A0A1D5NVV7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NVV7", "type": "external" } ], "mass": 72462.0, "length": 658, "protein_name": "Syntabulin", "gene_name": "SYBU", "organism": "Chicken", "refseq_name": "syntabulin isoform X1", "refseq_ac": [ { "id": "XP_015138500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138500", "type": "external" } ], "gene_names_uniprotkb": "SYBU", "gene_names_refseq": "SYBU", "protein_names_uniprotkb": "Syntabulin", "protein_names_refseq": "syntabulin isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:420277)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0043231 intracellular membrane-bounded organelle;GO:0031982 vesicle;GO:1904115 axon cytoplasm;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0060074 synapse maturation;GO:0019896 axonal transport of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NVV7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NW01-1", "uniprot_id": [ { "id": "A0A1D5NW01_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NW01", "type": "external" } ], "mass": 145491.0, "length": 1272, "protein_name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "gene_name": "KDM2A", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KDM2A", "gene_names_refseq": "", "protein_names_uniprotkb": "[histone H3]-dimethyl-L-lysine(36) demethylase; 1.14.11.27", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:425999)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.27", "type": "external" }, { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" }, { "id": "1.14.11.79", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.79", "type": "external" } ], "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity;GO:0032452 histone demethylase activity;GO:0045322 unmethylated CpG binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0042752 regulation of circadian rhythm;GO:0010944 negative regulation of transcription by competitive promoter binding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NW01-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NW22-1", "uniprot_id": [ { "id": "A0A1D5NW22_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NW22", "type": "external" } ], "mass": 59812.0, "length": 521, "protein_name": "TNFAIP3-interacting protein 2", "gene_name": "TNIP2", "organism": "Chicken", "refseq_name": "TNFAIP3-interacting protein 2", "refseq_ac": [ { "id": "NP_001026337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026337", "type": "external" } ], "gene_names_uniprotkb": "TNIP2", "gene_names_refseq": "TNIP2", "protein_names_uniprotkb": "TNFAIP3-interacting protein 2; A20-binding inhibitor of NF-kappa-B activation 2", "protein_names_refseq": "TNFAIP3-interacting protein 2", "tax_id": 9031, "disease": "", "pathway": " (gga:422884); (R-GGA-5684264); (R-GGA-5689896)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ851742.1, SRR13267659.213969.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On Mar 12, 2015 this sequence version replaced NP_001026337.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0070498 interleukin-1-mediated signaling pathway;GO:0023035 CD40 signaling pathway;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NW22-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NW85-1", "uniprot_id": [ { "id": "A0A1D5NW85_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NW85", "type": "external" } ], "mass": 20187.0, "length": 178, "protein_name": "Extracellular fatty acid-binding protein", "gene_name": "EXFABP", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "EXFABP", "gene_names_refseq": "", "protein_names_uniprotkb": "Extracellular fatty acid-binding protein", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-804914)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070538 oleic acid binding;GO:0050544 arachidonate binding;GO:0070539 linoleic acid binding;GO:0070540 stearic acid binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0006954 inflammatory response;GO:0007507 heart development;GO:0008284 positive regulation of cell population proliferation;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NW85-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NW93-1", "uniprot_id": [ { "id": "A0A1D5NW93_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NW93", "type": "external" } ], "mass": 16817.0, "length": 161, "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "ATP5D", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ATP5D", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP synthase F(1) complex subunit delta, mitochondrial; ATP synthase F1 subunit delta; F-ATPase delta subunit", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-163210); (R-GGA-8949613)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. With the central stalk subunit gamma, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:0042776 proton motive force-driven mitochondrial ATP synthesis;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NW93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWE1-1", "uniprot_id": [ { "id": "A0A1D5NWE1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWE1", "type": "external" } ], "mass": 35669.0, "length": 319, "protein_name": "peptidylprolyl isomerase", "gene_name": "FKBP6", "organism": "Chicken", "refseq_name": "inactive peptidyl-prolyl cis-trans isomerase FKBP6", "refseq_ac": [ { "id": "XP_015151391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151391", "type": "external" } ], "gene_names_uniprotkb": "FKBP6", "gene_names_refseq": "FKBP6", "protein_names_uniprotkb": "peptidylprolyl isomerase; 5.2.1.8", "protein_names_refseq": "inactive peptidyl-prolyl cis-trans isomerase FKBP6", "tax_id": 9031, "disease": "", "pathway": " (gga:417460)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051879 Hsp90 protein binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0001650 fibrillar center;GO:0015630 microtubule cytoskeleton;GO:0045171 intercellular bridge", "go_biological_process": "GO:0007283 spermatogenesis;GO:0006457 protein folding;GO:0034587 piRNA processing;GO:0051321 meiotic cell cycle;GO:0045070 positive regulation of viral genome replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWE1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWF7-1", "uniprot_id": [ { "id": "A0A1D5NWF7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWF7", "type": "external" } ], "mass": 30683.0, "length": 278, "protein_name": "Distal-less homeobox 3", "gene_name": "DLX3", "organism": "Chicken", "refseq_name": "homeobox protein DLX-3", "refseq_ac": [ { "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135", "type": "external" } ], "gene_names_uniprotkb": "DLX3", "gene_names_refseq": "DLX3", "protein_names_uniprotkb": "Distal-less homeobox 3", "protein_names_refseq": "DLX3 homeodomain containing protein; homeobox protein DLX-3", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "15672396;16323080;26598618", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992484, SAMEA103992527 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000735.1. On Mar 13, 2018 this sequence version replaced NP_990135.1., [RefSeq]; Dlx3 gene expression is described in the forebrain of chicken embryos; this constitutes the first documented evidence of expression of either Dlx3 or Dlx4 in the vertebrate central nervous system, [RefSeq, PubMed]; Inner ear expression patterns of Dlx3, Dlx5, and Dlx6 were examined during the first 7 days of chicken embryonic development., [RefSeq, PubMed]; KDM4B plays a critical role during inner ear invagination via modulating histone methylation of the direct target Dlx3., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030855 epithelial cell differentiation;GO:0048706 embryonic skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A1D5NWF7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWM8-1", "uniprot_id": [ { "id": "A0A1D5NWM8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWM8", "type": "external" } ], "mass": 37366.0, "length": 324, "protein_name": "Ras association domain family member 2", "gene_name": "RASSF2", "organism": "Chicken", "refseq_name": "ras association domain-containing protein 2", "refseq_ac": [ { "id": "NP_001026055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026055", "type": "external" } ], "gene_names_uniprotkb": "RASSF2", "gene_names_refseq": "RASSF2", "protein_names_uniprotkb": "Ras association domain family member 2", "protein_names_refseq": "Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; ras association domain-containing protein 2", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "25185950", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01000504.1, AJ719372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000331.1. On Sep 23, 2021 this sequence version replaced NP_001026055.1., [RefSeq]; The expression of piRNA-linked gene RASSF2 was higher in the chicken primordial germ cells than that of stage X blastoderms, gonadal stromal cells and embryonic fibroblasts. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0046330 positive regulation of JNK cascade;GO:0001501 skeletal system development;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NWM8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWN1-1", "uniprot_id": [ { "id": "A0A1D5NWN1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWN1", "type": "external" } ], "mass": 41983.0, "length": 380, "protein_name": "E3 ubiquitin-protein ligase KCMF1", "gene_name": "LOC431003", "organism": "Chicken", "refseq_name": "E3 ubiquitin-protein ligase KCMF1 isoform X1", "refseq_ac": [ { "id": "XP_025000351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000351", "type": "external" } ], "gene_names_uniprotkb": "LOC431003", "gene_names_refseq": "LOC431003", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase KCMF1; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase KCMF1 isoform X1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1D5P0W9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0005764 lysosome;GO:0005770 late endosome", "go_biological_process": "GO:0099536 synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWN1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWN7-1", "uniprot_id": [ { "id": "A0A1D5NWN7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWN7", "type": "external" } ], "mass": 30074.0, "length": 272, "protein_name": "Transmembrane protein 106C", "gene_name": "TMEM106C", "organism": "Chicken", "refseq_name": "transmembrane protein 106C isoform X1", "refseq_ac": [ { "id": "XP_015128097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128097", "type": "external" } ], "gene_names_uniprotkb": "TMEM106C", "gene_names_refseq": "TMEM106C", "protein_names_uniprotkb": "Transmembrane protein 106C", "protein_names_refseq": "transmembrane protein 106C isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:426186)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWN7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWN8-1", "uniprot_id": [ { "id": "A0A1D5NWN8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWN8", "type": "external" } ], "mass": 51968.0, "length": 465, "protein_name": "GDNF family receptor alpha-2", "gene_name": "GFRA2", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GFRA2", "gene_names_refseq": "", "protein_names_uniprotkb": "GDNF family receptor alpha-2; GDNF receptor alpha-2", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-5673001); (R-GGA-8853659)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons. NRTN-binding leads to autophosphorylation and activation of the RET receptor. 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in the turnover of nuclear polyadenylated (pA+) RNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWP6-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWQ1-1", "uniprot_id": [ { "id": "A0A1D5NWQ1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWQ1", "type": "external" } ], "mass": 35068.0, "length": 338, "protein_name": "Solute carrier family 25 member 34", "gene_name": "SLC25A34", "organism": "Chicken", "refseq_name": "solute carrier family 25 member 34", "refseq_ac": [ { "id": "XP_015152658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152658", "type": "external" } ], "gene_names_uniprotkb": "SLC25A34", "gene_names_refseq": "SLC25A34", "protein_names_uniprotkb": "Solute carrier family 25 member 34", "protein_names_refseq": "solute carrier family 25 member 34", "tax_id": 9031, "disease": "", "pathway": " (gga:107054933)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWQ1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWQ4-1", "uniprot_id": [ { "id": "A0A1D5NWQ4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWQ4", "type": "external" } ], "mass": 72733.0, "length": 675, "protein_name": "Sodium-dependent phosphate transport protein 2A", "gene_name": "SLC34A1", "organism": "Chicken", "refseq_name": "sodium-dependent phosphate transport protein 2A isoform X2", "refseq_ac": [ { "id": "XP_015149331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149331", "type": "external" } ], "gene_names_uniprotkb": "SLC34A1", "gene_names_refseq": "SLC34A1", "protein_names_uniprotkb": "Sodium-dependent phosphate transport protein 2A; Na(+)-dependent phosphate cotransporter 2A; Sodium/phosphate cotransporter 2A; Solute carrier family 34 member 1", "protein_names_refseq": "sodium-dependent phosphate transport protein 2A isoform X2", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-427589); (R-GGA-5683826)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. The cotransport has a Na(+):Pi stoichiometry of 3:1 and is electrogenic., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005436 sodium:phosphate symporter activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005903 brush border;GO:0016607 nuclear speck;GO:0016324 apical plasma membrane;GO:0031982 vesicle", "go_biological_process": "GO:0010288 response to lead ion;GO:0046686 response to cadmium ion;GO:0046689 response to mercury ion;GO:0030643 intracellular phosphate ion homeostasis;GO:0044341 sodium-dependent phosphate transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWQ4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWR5-1", "uniprot_id": [ { "id": "A0A1D5NWR5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWR5", "type": "external" } ], "mass": 40675.0, "length": 370, "protein_name": "Protein FAM110B", "gene_name": "FAM110B", "organism": "Chicken", "refseq_name": "protein FAM110B isoform X1", "refseq_ac": [ { "id": "XP_004939923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939923", "type": "external" } ], "gene_names_uniprotkb": "FAM110B", "gene_names_refseq": "FAM110B", "protein_names_uniprotkb": "Protein FAM110B", "protein_names_refseq": "protein FAM110B isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:421134)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWR5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWT4-1", "uniprot_id": [ { "id": "A0A1D5NWT4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWT4", "type": "external" } ], "mass": 83609.0, "length": 740, "protein_name": "Ribosomal protein S6 kinase", "gene_name": "RPS6KA3", "organism": "Chicken", "refseq_name": "ribosomal protein S6 kinase alpha-3 isoform X1", "refseq_ac": [ { "id": "XP_015128149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128149", "type": "external" } ], "gene_names_uniprotkb": "RPS6KA3", "gene_names_refseq": "RPS6KA3", "protein_names_uniprotkb": "Ribosomal protein S6 kinase; 2.7.11.1", "protein_names_refseq": "ribosomal protein S6 kinase alpha-3 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-198753); (R-GGA-199920); (R-GGA-2559582); (R-GGA-442742); (R-GGA-444257); (R-GGA-881907)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015128149.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" } ], "go_molecular_function": "GO:0004711 ribosomal protein S6 kinase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0032496 response to lipopolysaccharide;GO:0043066 negative regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0038202 TORC1 signaling;GO:0002224 toll-like receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWT4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWT9-1", "uniprot_id": [ { "id": "A0A1D5NWT9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWT9", "type": "external" } ], "mass": 13716.0, "length": 123, "protein_name": "Piercer of microtubule wall 1", "gene_name": "C9orf116", "organism": "Chicken", "refseq_name": "UPF0691 protein C9orf116 homolog isoform X1", "refseq_ac": [ { "id": "XP_024997291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997291", "type": "external" } ], "gene_names_uniprotkb": "C9orf116", "gene_names_refseq": "C9orf116", "protein_names_uniprotkb": "Piercer of microtubule wall 1", "protein_names_refseq": "UPF0691 protein C9orf116 homolog isoform X1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0036126 sperm flagellum;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0006974 DNA damage response;GO:0010468 regulation of gene expression;GO:0035082 axoneme assembly;GO:0071494 cellular response to UV-C", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWT9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWW5-1", "uniprot_id": [ { "id": "A0A1D5NWW5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWW5", "type": "external" } ], "mass": 43471.0, "length": 396, "protein_name": "KLF transcription factor 12", "gene_name": "KLF12", "organism": "Chicken", "refseq_name": "Krueppel-like factor 12 isoform X1", "refseq_ac": [ { "id": "XP_003640604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640604", "type": "external" } ], "gene_names_uniprotkb": "KLF12", "gene_names_refseq": "KLF12", "protein_names_uniprotkb": "KLF transcription factor 12", "protein_names_refseq": "Krueppel-like factor 12 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:418817)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWW5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWX3-1", "uniprot_id": [ { "id": "A0A1D5NWX3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWX3", "type": "external" } ], "mass": 34472.0, "length": 299, "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GGPS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Geranylgeranyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.10; 2.5.1.1; 2.5.1.29; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranyltranstransferase", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:427092); (R-GGA-9969896)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1D5NTV1", "ec_number_list": [ { "id": "2.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.1", "type": "external" }, { "id": "2.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.10", "type": "external" }, { "id": "2.5.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.29", "type": "external" } ], "go_molecular_function": "GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0004311 geranylgeranyl diphosphate synthase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0030018 Z disc", "go_biological_process": "GO:0008299 isoprenoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWX3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWY4-1", "uniprot_id": [ { "id": "A0A1D5NWY4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWY4", "type": "external" } ], "mass": 66265.0, "length": 580, "protein_name": "Kelch like family member 38", "gene_name": "KLHL38", "organism": "Chicken", "refseq_name": "kelch-like protein 38", "refseq_ac": [ { "id": "NP_001376390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376390", "type": "external" } ], "gene_names_uniprotkb": "KLHL38", "gene_names_refseq": "KLHL38", "protein_names_uniprotkb": "Kelch like family member 38", "protein_names_refseq": "kelch-like 38; kelch-like protein 38", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## CDS exon combination :: SRR12888538.69114.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000044.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWY4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NWZ6-1", "uniprot_id": [ { "id": "A0A1D5NWZ6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NWZ6", "type": "external" } ], "mass": 39125.0, "length": 343, "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "organism": "Chicken", "refseq_name": "ganglioside-induced differentiation-associated protein 1 isoform X1", "refseq_ac": [ { "id": "XP_418303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418303", "type": "external" } ], "gene_names_uniprotkb": "GDAP1", "gene_names_refseq": "GDAP1", "protein_names_uniprotkb": "Ganglioside-induced differentiation-associated protein 1", "protein_names_refseq": "ganglioside-induced differentiation-associated protein 1 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-9603798)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418303.2. COMPLETENESS: full length., [RefSeq]; Regulates the mitochondrial network by promoting mitochondrial fission., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol", "go_biological_process": "GO:0032526 response to retinoic acid;GO:0006626 protein targeting to mitochondrion;GO:0008053 mitochondrial fusion;GO:0000266 mitochondrial fission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NWZ6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX23-1", "uniprot_id": [ { "id": "A0A1D5NX23_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX23", "type": "external" } ], "mass": 104882.0, "length": 935, "protein_name": "Zinc finger protein 280D", "gene_name": "ZNF280D", "organism": "Chicken", "refseq_name": "zinc finger protein 280D isoform X1", "refseq_ac": [ { "id": "XP_004943836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943836", "type": "external" } ], "gene_names_uniprotkb": "ZNF280D", "gene_names_refseq": "ZNF280D", "protein_names_uniprotkb": "Zinc finger protein 280D", "protein_names_refseq": "zinc finger protein 280D isoform X1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_004943836.2. COMPLETENESS: full length., [RefSeq]; May function as a transcription factor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX23-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX31-1", "uniprot_id": [ { "id": "A0A1D5NX31_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX31", "type": "external" } ], "mass": 29154.0, "length": 258, "protein_name": "Carbonic anhydrase", "gene_name": "CA13", "organism": "Chicken", "refseq_name": "carbonic anhydrase 13", "refseq_ac": [ { "id": "XP_003640859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640859", "type": "external" } ], "gene_names_uniprotkb": "CA13", "gene_names_refseq": "CA13", "protein_names_uniprotkb": "Carbonic anhydrase; 4.2.1.1", "protein_names_refseq": "carbonic anhydrase 13", "tax_id": 9031, "disease": "", "pathway": " (gga:100858989); (R-GGA-1475029)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Reversible hydration of carbon dioxide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1", "type": "external" }, { "id": "4.2.1.69", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.69", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0043209 myelin sheath;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX31-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX62-1", "uniprot_id": [ { "id": "A0A1D5NX62_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX62", "type": "external" } ], "mass": 47239.0, "length": 438, "protein_name": "Forkhead box A2", "gene_name": "FOXA2", "organism": "Chicken", "refseq_name": "hepatocyte nuclear factor 3-beta", "refseq_ac": [ { "id": "NP_990101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990101", "type": "external" } ], "gene_names_uniprotkb": "FOXA2", "gene_names_refseq": "FOXA2; HNF-3BETA", "protein_names_uniprotkb": "Forkhead box A2", "protein_names_refseq": "hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3beta; transcription factor Foxa2", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "20849957;22750257;24401371", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.162574.1, AF150749.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992527 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000060.1. On Oct 1, 2021 this sequence version replaced NP_990101.1., [RefSeq]; Data suggest that Nato3 is a direct target of Foxa2, a transcription activator and effector of Sonic hedgehog, the hallmark regulator of neural tube floor plate induction and spinal cord development., [RefSeq, PubMed]; Nato3 induces ectopic Foxa2-positive cells and indirectly downregulates Nkx2.2 expression., [RefSeq, PubMed]; The transcription factor FOXA2 can execute the full midbrain and spinal cord floor plate program via HH-independent and dependent mechanisms., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0030054 cell junction", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0031018 endocrine pancreas development;GO:0030193 regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A1D5NX62-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX74-1", "uniprot_id": [ { "id": "A0A1D5NX74_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX74", "type": "external" } ], "mass": 158905.0, "length": 1420, "protein_name": "Family with sequence similarity 135 member B", "gene_name": "FAM135B", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FAM135B", "gene_names_refseq": "", "protein_names_uniprotkb": "Family with sequence similarity 135 member B", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX74-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX83-1", "uniprot_id": [ { "id": "A0A1D5NX83_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX83", "type": "external" } ], "mass": 55843.0, "length": 492, "protein_name": "PHD finger protein 10", "gene_name": "PHF10", "organism": "Chicken", "refseq_name": "PHD finger protein 10 isoform X1", "refseq_ac": [ { "id": "XP_015139860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139860", "type": "external" } ], "gene_names_uniprotkb": "PHF10", "gene_names_refseq": "PHF10", "protein_names_uniprotkb": "PHD finger protein 10", "protein_names_refseq": "PHD finger protein 10 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:100857350); (R-GGA-9933939); (R-GGA-9933946); (R-GGA-9934037)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity;GO:0004402 histone acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0071564 npBAF complex;GO:0000785 chromatin", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX83-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX84-1", "uniprot_id": [ { "id": "A0A1D5NX84_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX84", "type": "external" } ], "mass": 42998.0, "length": 386, "protein_name": "TraB domain containing", "gene_name": "TRABD", "organism": "Chicken", "refseq_name": "traB domain-containing protein isoform X1", "refseq_ac": [ { "id": "XP_046763094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763094", "type": "external" } ], "gene_names_uniprotkb": "TRABD", "gene_names_refseq": "TRABD", "protein_names_uniprotkb": "TraB domain containing", "protein_names_refseq": "traB domain-containing protein isoform X1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0160204 mitochondrion-mitochondrion outer membrane tether activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0008053 mitochondrial fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX84-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX87-1", "uniprot_id": [ { "id": "A0A1D5NX87_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX87", "type": "external" } ], "mass": 30266.0, "length": 261, "protein_name": "tRNA selenocysteine-associated protein 1", "gene_name": "C2H6orf52", "organism": "Chicken", "refseq_name": "tRNA selenocysteine 1-associated protein 1 isoform 2", "refseq_ac": [ { "id": "NP_001238944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001238944", "type": "external" } ], "gene_names_uniprotkb": "C2H6orf52", "gene_names_refseq": "C2H6orf52; TRNAU1AP", "protein_names_uniprotkb": "tRNA selenocysteine-associated protein 1", "protein_names_refseq": "tRNA selenocysteine 1-associated protein 1 isoform 2; tRNA selenocysteine 1-associated protein 1", "tax_id": 9031, "disease": "", "pathway": " (gga:420849)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01018777.1, HAEL01003831.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000040.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX87-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NX91-1", "uniprot_id": [ { "id": "A0A1D5NX91_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NX91", "type": "external" } ], "mass": 76514.0, "length": 741, "protein_name": "Interferon regulatory factor 2 binding protein like", "gene_name": "C5H14orf4", "organism": "Chicken", "refseq_name": "probable E3 ubiquitin-protein ligase IRF2BPL", "refseq_ac": [ { "id": "XP_015143203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143203", "type": "external" } ], "gene_names_uniprotkb": "C5H14orf4", "gene_names_refseq": "C5H14orf4", "protein_names_uniprotkb": "Interferon regulatory factor 2 binding protein like", "protein_names_refseq": "probable E3 ubiquitin-protein ligase IRF2BPL", "tax_id": 9031, "disease": "", "pathway": " (gga:429422)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NX91-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXA5-1", "uniprot_id": [ { "id": "A0A1D5NXA5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXA5", "type": "external" } ], "mass": 61149.0, "length": 548, "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "SVOP", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SVOP", "gene_names_refseq": "", "protein_names_uniprotkb": "Synaptic vesicle 2-related protein", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:416895)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0030672 synaptic vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXA5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXC6-1", "uniprot_id": [ { "id": "A0A1D5NXC6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXC6", "type": "external" } ], "mass": 52230.0, "length": 476, "protein_name": "Sec61 translocon alpha 2 subunit", "gene_name": "SEC61A2", "organism": "Chicken", "refseq_name": "protein transport protein Sec61 subunit alpha", "refseq_ac": [ { "id": "NP_001308549", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308549", "type": "external" } ], "gene_names_uniprotkb": "SEC61A2", "gene_names_refseq": "SEC61A2", "protein_names_uniprotkb": "Sec61 translocon alpha 2 subunit", "protein_names_refseq": "Sec61 alpha 2 subunit; 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The reference sequence was derived from JAENSK010000011.1. On Mar 29, 2016 this sequence version replaced XP_015153366.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005048 signal sequence binding;GO:0043022 ribosome binding;GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005784 Sec61 translocon complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation;GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXC6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXF3-1", "uniprot_id": [ { "id": "A0A1D5NXF3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXF3", "type": "external" } ], "mass": 78059.0, "length": 732, "protein_name": "T-box transcription factor 3", "gene_name": "TBX3", "organism": "Chicken", "refseq_name": "T-box transcription factor TBX3", "refseq_ac": [ { "id": "NP_001257807", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257807", "type": "external" } ], "gene_names_uniprotkb": "TBX3", "gene_names_refseq": "TBX3", "protein_names_uniprotkb": "T-box transcription factor 3", "protein_names_refseq": "T-Box protein 3; T-box 3; T-box transcription factor TBX3", "tax_id": 9031, "disease": "", "pathway": " (gga:374202)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14723846", "class_list": "", "function": "Misexpression of Tbx2 and Tbx3 induced posterior homeotic transformation of digit III to digit IV and digit II to digit III, respectively. Erratum:[Dev Cell. 2005 Jun;8(6):971-2], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005929 cilium;GO:0000785 chromatin", "go_biological_process": "GO:0061017 hepatoblast differentiation;GO:0001708 cell fate specification;GO:0032275 luteinizing hormone secretion;GO:0046884 follicle-stimulating hormone secretion;GO:0030540 female genitalia development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NXF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXI7-1", "uniprot_id": [ { "id": "A0A1D5NXI7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXI7", "type": "external" } ], "mass": 70119.0, "length": 645, "protein_name": "Eyes absent homolog", "gene_name": "EYA4", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "EYA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-5693565)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair;GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXI7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXK4-1", "uniprot_id": [ { "id": "A0A1D5NXK4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXK4", "type": "external" } ], "mass": 61973.0, "length": 549, "protein_name": "Family with sequence similarity 124 member A", "gene_name": "FAM124A", "organism": "Chicken", "refseq_name": "protein FAM124A", "refseq_ac": [ { "id": "XP_001233732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233732", "type": "external" } ], "gene_names_uniprotkb": "FAM124A", "gene_names_refseq": "FAM124A", "protein_names_uniprotkb": "Family with sequence similarity 124 member A", "protein_names_refseq": "protein FAM124A", "tax_id": 9031, "disease": "", "pathway": " (gga:770395)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_001233732.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXK4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXK6-1", "uniprot_id": [ { "id": "A0A1D5NXK6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXK6", "type": "external" } ], "mass": 111160.0, "length": 1017, "protein_name": "DNA damage inducible 1 homolog 2", "gene_name": "DDI2", "organism": "Chicken", "refseq_name": "regulatory solute carrier protein family 1 member 1 isoform X1", "refseq_ac": [ { "id": "XP_015152776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152776", "type": "external" } ], "gene_names_uniprotkb": "DDI2", "gene_names_refseq": "DDI2", "protein_names_uniprotkb": "DNA damage inducible 1 homolog 2", "protein_names_refseq": "regulatory solute carrier protein family 1 member 1 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:425541)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0097752 regulation of DNA stability;GO:0051603 proteolysis involved in protein catabolic process;GO:0072711 cellular response to hydroxyurea", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXK6-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXK7-1", "uniprot_id": [ { "id": "A0A1D5NXK7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXK7", "type": "external" } ], "mass": 17259.0, "length": 155, "protein_name": "Prefoldin subunit 5", "gene_name": "PFDN5", "organism": "Chicken", "refseq_name": "prefoldin subunit 5", "refseq_ac": [ { "id": "XP_003643470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643470", "type": "external" } ], "gene_names_uniprotkb": "PFDN5", "gene_names_refseq": "PFDN5", "protein_names_uniprotkb": "Prefoldin subunit 5", "protein_names_refseq": "prefoldin subunit 5", "tax_id": 9031, "disease": "", "pathway": " (gga:100859376)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0045111 intermediate filament cytoskeleton;GO:0016272 prefoldin complex", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0045892 negative regulation of DNA-templated transcription;GO:0006457 protein folding;GO:1905907 negative regulation of amyloid fibril formation;GO:1990114 RNA polymerase II core complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXK7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXL9-1", "uniprot_id": [ { "id": "A0A1D5NXL9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXL9", "type": "external" } ], "mass": 43458.0, "length": 399, "protein_name": "Homeobox B3", "gene_name": "HOXB3", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HOXB3", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeobox B3", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:395502)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A1D5NYH9;A0A1D5PBV1", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0030878 thyroid gland development;GO:0021546 rhombomere development;GO:0021615 glossopharyngeal nerve morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXL9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXQ2-1", "uniprot_id": [ { "id": "A0A1D5NXQ2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXQ2", "type": "external" } ], "mass": 64300.0, "length": 590, "protein_name": "Protein phosphatase, Mg2+/Mn2+ dependent 1D", "gene_name": "PPM1D", "organism": "Chicken", "refseq_name": "protein phosphatase 1D", "refseq_ac": [ { "id": "XP_415890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415890", "type": "external" } ], "gene_names_uniprotkb": "PPM1D", "gene_names_refseq": "PPM1D", "protein_names_uniprotkb": "Protein phosphatase, Mg2+/Mn2+ dependent 1D", "protein_names_refseq": "protein phosphatase 1D", "tax_id": 9031, "disease": "", "pathway": " (gga:417644); (R-GGA-8878166)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_415890.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051019 mitogen-activated protein kinase binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:0000086 G2/M transition of mitotic cell cycle;GO:0009617 response to bacterium;GO:1902531 regulation of intracellular signal transduction;GO:0045814 negative regulation of gene expression, epigenetic;GO:0030330 DNA damage response, signal transduction by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXQ2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXS5-1", "uniprot_id": [ { "id": "A0A1D5NXS5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXS5", "type": "external" } ], "mass": 76950.0, "length": 692, "protein_name": "protein-glutamine gamma-glutamyltransferase", "gene_name": "TGM3", "organism": "Chicken", "refseq_name": "protein-glutamine gamma-glutamyltransferase E isoform X1", "refseq_ac": [ { "id": "XP_417392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417392", "type": "external" } ], "gene_names_uniprotkb": "TGM3", "gene_names_refseq": "TGM3", "protein_names_uniprotkb": "protein-glutamine gamma-glutamyltransferase; 2.3.2.13", "protein_names_refseq": "protein-glutamine gamma-glutamyltransferase E isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:419215)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_417392.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.13", "type": "external" }, { "id": "3.5.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.44", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0005509 calcium ion binding;GO:0003810 protein-glutamine gamma-glutamyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0030216 keratinocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXS5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NXS8-1", "uniprot_id": [ { "id": "A0A1D5NXS8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NXS8", "type": "external" } ], "mass": 71475.0, "length": 641, "protein_name": "Influenza virus NS1A binding protein", "gene_name": "IVNS1ABP", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IVNS1ABP", "gene_names_refseq": "", "protein_names_uniprotkb": "Influenza virus NS1A binding protein", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:426862)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1L1RZJ3", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0009615 response to virus;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008380 RNA splicing;GO:0097193 intrinsic apoptotic signaling pathway;GO:0031397 negative regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NXS8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY06-1", "uniprot_id": [ { "id": "A0A1D5NY06_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY06", "type": "external" } ], "mass": 33509.0, "length": 294, "protein_name": "Spermidine synthase", "gene_name": "SRM", "organism": "Chicken", "refseq_name": "spermidine synthase isoform X1", "refseq_ac": [ { "id": "XP_015152659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152659", "type": "external" } ], "gene_names_uniprotkb": "SRM", "gene_names_refseq": "SRM", "protein_names_uniprotkb": "Spermidine synthase; 2.5.1.16; Putrescine aminopropyltransferase", "protein_names_refseq": "spermidine synthase isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:771447); (R-GGA-351202)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.16", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0004766 spermidine synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:1990830 cellular response to leukemia inhibitory factor;GO:0008295 spermidine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NY06-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY14-1", "uniprot_id": [ { "id": "A0A1D5NY14_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY14", "type": "external" } ], "mass": 67064.0, "length": 584, "protein_name": "DENN domain containing 6A", "gene_name": "DENND6A", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DENND6A", "gene_names_refseq": "", "protein_names_uniprotkb": "DENN domain containing 6A", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0055037 recycling endosome", "go_biological_process": "GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NY14-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY17-1", "uniprot_id": [ { "id": "TM182_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY17", "type": "external" } ], "mass": 26287.0, "length": 233, "protein_name": "Transmembrane protein 182", "gene_name": "TMEM182", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TMEM182", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protein 182", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "15592404;34427057", "class_list": "", "function": "Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (PubMed:34427057). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (PubMed:34427057)., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:1901740 negative regulation of myoblast fusion;GO:0007517 muscle organ development;GO:0045662 negative regulation of myoblast differentiation;GO:0014908 myotube differentiation involved in skeletal muscle regeneration;GO:0014906 myotube cell development involved in skeletal muscle regeneration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NY17-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY46-1", "uniprot_id": [ { "id": "A0A1D5NY46_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY46", "type": "external" } ], "mass": 40415.0, "length": 363, "protein_name": "POU domain protein", "gene_name": "POU1F1", "organism": "Chicken", "refseq_name": "pituitary-specific positive transcription factor 1 isoform 1", "refseq_ac": [ { "id": "NP_001383031", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383031", "type": "external" } ], "gene_names_uniprotkb": "POU1F1", "gene_names_refseq": "GHF-1; PIT-1; PIT1; POU1F1; Pit-1*", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1); Pit-1/GHF-1; pituitary specific transcription factor-1; pituitary specific transcription factor; pituitary-specific positive transcription factor 1 isoform 1; pituitary-specific positive transcription factor 1 variant alpha", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "14967913;15595273;18304318;22499861;22581457", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ236856.1 [ECO:0000332] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000019.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Analysis of differential abilities of chicken Pit1 isoforms to regulate the GH promoter, [RefSeq, PubMed]; Our study found that polymorphisms of PIT1 gene and their haplotypes were associated with chicken growth traits and not with carcass and fatty traits Publication Status: Online-Only, [RefSeq, PubMed]; Pit-1 has a role in mediating the stimulatory effects of TRH on pituitary hormones like GH., [RefSeq, PubMed]; Pit-1 protein induction occurs in 6 types of glandular cells, suggesting that Pit-1 may regulate hormone synthesis in each glandular cell in the anterior pituitary., [RefSeq, PubMed]; The Pit-1 gene is polymorphic and has a significant effect on growth traits in chickens., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A1D5NY46-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY75-1", "uniprot_id": [ { "id": "A0A1D5NY75_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY75", "type": "external" } ], "mass": 48640.0, "length": 450, "protein_name": "One cut domain family member", "gene_name": "ONECUT1", "organism": "Chicken", "refseq_name": "hepatocyte nuclear factor 6 isoform X2", "refseq_ac": [ { "id": "XP_015147374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147374", "type": "external" } ], "gene_names_uniprotkb": "ONECUT1", "gene_names_refseq": "ONECUT1", "protein_names_uniprotkb": "One cut domain family member", "protein_names_refseq": "hepatocyte nuclear factor 6 isoform X2", "tax_id": 9031, "disease": "", "pathway": " (gga:107054176)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0001889 liver development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007219 Notch signaling pathway;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NY75-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY81-1", "uniprot_id": [ { "id": "A0A1D5NY81_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY81", "type": "external" } ], "mass": 42775.0, "length": 384, "protein_name": "Proton-coupled zinc antiporter SLC30A8", "gene_name": "SLC30A8", "organism": "Chicken", "refseq_name": "zinc transporter 8 isoform X1", "refseq_ac": [ { "id": "XP_025003910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003910", "type": "external" } ], "gene_names_uniprotkb": "SLC30A8", "gene_names_refseq": "SLC30A8", "protein_names_uniprotkb": "Proton-coupled zinc antiporter SLC30A8; Solute carrier family 30 member 8; Zinc transporter 8", "protein_names_refseq": "zinc transporter 8 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-264876); (R-GGA-435368)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0140826 zinc:proton antiporter activity;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030658 transport vesicle membrane;GO:0030667 secretory granule membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0010043 response to zinc ion;GO:0009749 response to glucose;GO:0030073 insulin secretion;GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NY81-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NY89-1", "uniprot_id": [ { "id": "A0A1D5NY89_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NY89", "type": "external" } ], "mass": 73823.0, "length": 650, "protein_name": "FAS-associated factor 1", "gene_name": "FAF1", "organism": "Chicken", "refseq_name": "FAS-associated factor 1 isoform X1", "refseq_ac": [ { "id": "XP_015146711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146711", "type": "external" } ], "gene_names_uniprotkb": "FAF1", "gene_names_refseq": "FAF1", "protein_names_uniprotkb": "FAS-associated factor 1", "protein_names_refseq": "FAS-associated factor 1 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:424629)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0031072 heat shock protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0051059 NF-kappaB binding", "go_cellular_component": "GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0030155 regulation of cell adhesion;GO:0006915 apoptotic process;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0045732 positive regulation of protein catabolic process;GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NY89-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYE8-1", "uniprot_id": [ { "id": "A0A1D5NYE8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYE8", "type": "external" } ], "mass": 85480.0, "length": 781, "protein_name": "Catenin beta 1", "gene_name": "CTNNB1", "organism": "Chicken", "refseq_name": "catenin beta-1", "refseq_ac": [ { "id": "NP_990412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990412", "type": "external" } ], "gene_names_uniprotkb": "CTNNB1", "gene_names_refseq": "CHBCAT; CTNNB1; beta-catenin", "protein_names_uniprotkb": "Catenin beta 1", "protein_names_refseq": "beta catenin; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-195253); (R-GGA-196299); (R-GGA-201681); (R-GGA-201722); (R-GGA-3134973); (R-GGA-351906); (R-GGA-3769402); (R-GGA-4086398); (R-GGA-418990); (R-GGA-5218920); (R-GGA-525793); (R-GGA-8951430); (R-GGA-9762292); (R-GGA-9764561); (R-GGA-9766229); (R-GGA-9768727); (R-GGA-9825892)", "pathway_count": 17, "publication_count": 6, "publication_id_list": "11290326;14991726;27218451;27664768;28842809;30009960", "class_list": "", "function": "Beta-catenin may be involved in regulating adhesive properties of cells during chick gastrulation, [RefSeq, PubMed]; Beta-catenin role in the cardiomyocyte differentiation during chick cardiogenesis., [RefSeq, PubMed]; CTNNB1 signaling is required for embryonic forelimb and hindlimb development and this WNT/CTNNB1 pathway is triggered by different WNT factors at different axial levels, [RefSeq, PubMed]; Cytoplasmic NOTCH and membrane-derived beta-catenin link cell fate choice to epithelial-mesenchymal transition during myogenesis. Publication Status: Online-Only, [RefSeq, PubMed]; We demonstrate that the balance of Ecad and Ncad is dependent upon the availability of beta-catenin proteins, and that alteration of either classical cadherin modifies the proportions of the neural crest and neuroectodermal cells that are specified, [RefSeq, PubMed]; We show that b-catenin is expressed during the pre-patterning of the epithelium prior to papilla induction and second that b-catenin, Ednrb and Inhba are expressed during the induction and patterning of the conjunctival papillae. Furthermore, we identified two genes, b-catenin and Prox1, that may be involved in the induction of the underlying scleral bones, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1L1RRU8", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098831 presynaptic active zone cytoplasmic component;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0090279 regulation of calcium ion import;GO:0030316 osteoclast differentiation;GO:0030997 regulation of centriole-centriole cohesion;GO:1904888 cranial skeletal system development;GO:0001708 cell fate specification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A1D5NYE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYE9-1", "uniprot_id": [ { "id": "A0A1D5NYE9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYE9", "type": "external" } ], "mass": 90068.0, "length": 799, "protein_name": "Dystrobrevin alpha", "gene_name": "DTNA", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DTNA", "gene_names_refseq": "", "protein_names_uniprotkb": "Dystrobrevin alpha", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-9913351)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0045202 synapse;GO:0005654 nucleoplasm;GO:0045111 intermediate filament cytoskeleton", "go_biological_process": "GO:0099536 synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYE9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYF3-1", "uniprot_id": [ { "id": "A0A1D5NYF3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYF3", "type": "external" } ], "mass": 14921.0, "length": 132, "protein_name": "Fatty acid binding protein 4", "gene_name": "FABP4", "organism": "Chicken", "refseq_name": "fatty acid-binding protein, adipocyte", "refseq_ac": [ { "id": "NP_989621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989621", "type": "external" } ], "gene_names_uniprotkb": "FABP4", "gene_names_refseq": "A-FABP; AFABP; FABP4; FABP", "protein_names_uniprotkb": "Fatty acid binding protein 4", "protein_names_refseq": "adipocyte fatty acid binding protein; adipocyte-type fatty acid binding protein; fatty acid binding protein 4, adipocyte; fatty acid-binding protein, adipocyte", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-163560)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "15595698;16553271;18607791;19595785;20024783;20075270;21377972;21489952;31276245", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CF252119.1, BU414318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000044.1. On Sep 23, 2021 this sequence version replaced NP_989621.1., [RefSeq]; A-FABP gene polymorphisms were associated with muscle stomach weight but no significant effect on any other trait., [RefSeq, PubMed]; A-FABP knockdown might lead to decreased lipid accumulation and upregulated expression of PPAR-gamma in chicken adipocytes., [RefSeq, PubMed]; Cloning and characterization of the gene and its homology with other species., [RefSeq, PubMed]; Increased mRNA expression of A-FABP is directly correlated with intramuscular fat percentage, and mRNA levels increase with age., [RefSeq, PubMed]; Results indicated that an A-FABP gene polymorphism was associated with abdominal fat weight and percentage of abdominal fat, and the A-FABP gene could be a candidate locus or linked to a major gene(s) that affects abdominal fat content in the chicken, [RefSeq, PubMed]; SNPs identified with genetic potential to produce more desirable muscle with higher intramuscular fat in Beijing-You chickens, [RefSeq, PubMed]; Ser89Asn polymorphism may influence chicken adipocyte fatty acid-binding protein function and ultimately lipid deposition through changing the ligand-binding activity., [RefSeq, PubMed]; These findings provide fundamental data that might be useful in further study of the role of the A-FABP gene in IMF content and fatty metabolism in chickens., [RefSeq, PubMed]; These results suggested that chicken A-FABP might affect abdominal fat deposition through changing its expression level., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0036041 long-chain fatty acid binding;GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005504 fatty acid binding;GO:0051427 hormone receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0050872 white fat cell differentiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0009617 response to bacterium;GO:0015908 fatty acid transport;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A1D5NYF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYF8-1", "uniprot_id": [ { "id": "A0A1D5NYF8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYF8", "type": "external" } ], "mass": 35180.0, "length": 320, "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "organism": "Chicken", "refseq_name": "protein SEC13 homolog", "refseq_ac": [ { "id": "NP_001264770", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264770", "type": "external" } ], "gene_names_uniprotkb": "SEC13", "gene_names_refseq": "SEC13L1; SEC13", "protein_names_uniprotkb": "Protein SEC13 homolog; GATOR2 complex protein SEC13; SEC13-like protein 1", "protein_names_refseq": "SEC13-like 1; protein SEC13 homolog", "tax_id": 9031, "disease": "", "pathway": " (gga:416119); (R-GGA-141430); (R-GGA-141444); (R-GGA-159227); (R-GGA-159230); (R-GGA-159231); (R-GGA-159236); (R-GGA-191859); (R-GGA-204005); (R-GGA-2467813); (R-GGA-2500257); (R-GGA-3108214); (R-GGA-3232142); (R-GGA-3301854); (R-GGA-4085377); (R-GGA-4551638); (R-GGA-5663220); (R-GGA-9615933); (R-GGA-9639288); (R-GGA-9648025); (R-GGA-983170)", "pathway_count": 21, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01012439.1, HAEL01000134.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. On Apr 24, 2013 this sequence version replaced XP_414450.3., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005765 lysosomal membrane;GO:0031080 nuclear pore outer ring;GO:0005654 nucleoplasm;GO:0000776 kinetochore", "go_biological_process": "GO:0015031 protein transport;GO:0051028 mRNA transport;GO:1904263 positive regulation of TORC1 signaling;GO:0090110 COPII-coated vesicle cargo loading;GO:0031669 cellular response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYF8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYG3-1", "uniprot_id": [ { "id": "A0A1D5NYG3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYG3", "type": "external" } ], "mass": 283981.0, "length": 2652, "protein_name": "Filamin B", "gene_name": "FLNB", "organism": "Chicken", "refseq_name": "filamin-B isoform X3", "refseq_ac": [ { "id": "XP_015148423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423", "type": "external" } ], "gene_names_uniprotkb": "FLNB", "gene_names_refseq": "FLNB; filamin-B", "protein_names_uniprotkb": "Filamin B", "protein_names_refseq": "filamin-B isoform X3", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYG3-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYI1-1", "uniprot_id": [ { "id": "A0A1D5NYI1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYI1", "type": "external" } ], "mass": 20076.0, "length": 173, "protein_name": "Uncharacterized protein", "gene_name": "LOC768589", "organism": "Chicken", "refseq_name": "baculoviral IAP repeat-containing protein 5.1", "refseq_ac": [ { "id": "XP_001231345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231345", "type": "external" } ], "gene_names_uniprotkb": "LOC768589", "gene_names_refseq": "LOC768589", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "baculoviral IAP repeat-containing protein 5.1", "tax_id": 9031, "disease": "", "pathway": " (gga:768589)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_001231345.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0051233 spindle midzone;GO:0000776 kinetochore;GO:0032133 chromosome passenger complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0043066 negative regulation of apoptotic process;GO:0000281 mitotic cytokinesis;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYI1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYI4-1", "uniprot_id": [ { "id": "A0A1D5NYI4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYI4", "type": "external" } ], "mass": 88865.0, "length": 797, "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "gene_name": "HHIPL1", "organism": "Chicken", "refseq_name": "HHIP-like protein 1", "refseq_ac": [ { "id": "XP_421358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421358", "type": "external" } ], "gene_names_uniprotkb": "HHIPL1", "gene_names_refseq": "HHIPL1", "protein_names_uniprotkb": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "protein_names_refseq": "HHIP-like protein 1", "tax_id": 9031, "disease": "", "pathway": " (gga:423448)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_421358.4. COMPLETENESS: full length., [RefSeq]; Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYI4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYJ2-1", "uniprot_id": [ { "id": "A0A1D5NYJ2_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYJ2", "type": "external" } ], "mass": 103646.0, "length": 932, "protein_name": "Lon protease homolog, mitochondrial", "gene_name": "LONP1", "organism": "Chicken", "refseq_name": "lon protease homolog, mitochondrial", "refseq_ac": [ { "id": "XP_001232112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232112", "type": "external" } ], "gene_names_uniprotkb": "LONP1", "gene_names_refseq": "LONP1", "protein_names_uniprotkb": "Lon protease homolog, mitochondrial; 3.4.21.53", "protein_names_refseq": "lon protease homolog, mitochondrial", "tax_id": 9031, "disease": "", "pathway": " (gga:768942); (R-GGA-9837999)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001232112.2. COMPLETENESS: full length., [RefSeq]; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "2.7.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.23", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "1.1.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.2.4", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "5.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0043531 ADP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0001666 response to hypoxia;GO:0034599 cellular response to oxidative stress;GO:0007005 mitochondrion organization;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0051131 chaperone-mediated protein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYJ2-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYK7-1", "uniprot_id": [ { "id": "A0A1D5NYK7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYK7", "type": "external" } ], "mass": 68371.0, "length": 580, "protein_name": "Moesin", "gene_name": "MSN", "organism": "Chicken", "refseq_name": "moesin", "refseq_ac": [ { "id": "NP_001376296", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376296", "type": "external" } ], "gene_names_uniprotkb": "MSN", "gene_names_refseq": "MSN", "protein_names_uniprotkb": "Moesin", "protein_names_refseq": "moesin", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-437239)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22219290", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.2558.1, SRR13267658.19149.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1., [RefSeq]; Ezrin/radixin/moesin proteins organize actin filaments in sensory neuron growth cones and are crucial for neurotrophin-induced remodeling of F-actin and redistribution of adhesion receptors., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding;GO:0050839 cell adhesion molecule binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:1902966 positive regulation of protein localization to early endosome;GO:0022614 membrane to membrane docking;GO:0061028 establishment of endothelial barrier;GO:1902115 regulation of organelle assembly;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NYK7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYL4-1", "uniprot_id": [ { "id": "A0A1D5NYL4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYL4", "type": "external" } ], "mass": 62945.0, "length": 570, "protein_name": "Myocyte enhancer factor 2D", "gene_name": "MEF2D", "organism": "Chicken", "refseq_name": "myocyte-specific enhancer factor 2D isoform X2", "refseq_ac": [ { "id": "XP_040508313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508313", "type": "external" } ], "gene_names_uniprotkb": "MEF2D", "gene_names_refseq": "MEF2D", "protein_names_uniprotkb": "Myocyte enhancer factor 2D", "protein_names_refseq": "myocyte-specific enhancer factor 2D isoform X2", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0042826 histone deacetylase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0007507 heart development;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation;GO:0007512 adult heart development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYL4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYL9-1", "uniprot_id": [ { "id": "A0A1D5NYL9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYL9", "type": "external" } ], "mass": 39373.0, "length": 344, "protein_name": "Leucine zipper protein 2", "gene_name": "LUZP2", "organism": "Chicken", "refseq_name": "leucine zipper protein 2", "refseq_ac": [ { "id": "NP_001186450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186450", "type": "external" } ], "gene_names_uniprotkb": "LUZP2", "gene_names_refseq": "LUZP2", "protein_names_uniprotkb": "Leucine zipper protein 2", "protein_names_refseq": "leucine zipper protein 2", "tax_id": 9031, "disease": "", "pathway": " (gga:423001)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## CDS exon combination :: HAEK01001471.1, HAEK01040797.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN08016554, SAMN08016668 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Dec 9, 2010 this sequence version replaced XP_420933.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYL9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYN9-1", "uniprot_id": [ { "id": "A0A1D5NYN9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYN9", "type": "external" } ], "mass": 22862.0, "length": 206, "protein_name": "Testis development related protein", "gene_name": "TDRP", "organism": "Chicken", "refseq_name": "testis development-related protein isoform X1", "refseq_ac": [ { "id": "XP_015140414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140414", "type": "external" } ], "gene_names_uniprotkb": "TDRP", "gene_names_refseq": "TDRP", "protein_names_uniprotkb": "Testis development related protein", "protein_names_refseq": "testis development-related protein isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:421905)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYN9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYP8-1", "uniprot_id": [ { "id": "A0A1D5NYP8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYP8", "type": "external" } ], "mass": 67555.0, "length": 626, "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "organism": "Chicken", "refseq_name": "SHC-transforming protein 1 isoform a", "refseq_ac": [ { "id": "NP_001280209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280209", "type": "external" } ], "gene_names_uniprotkb": "SHC1", "gene_names_refseq": "SHC1; SHC", "protein_names_uniprotkb": "SHC-transforming protein 1; Src homology 2 domain-containing-transforming protein C1", "protein_names_refseq": "SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 1 isoform a; adaptor protein SHC", "tax_id": 9031, "disease": "", "pathway": " (gga:395934); (R-GGA-1250196); (R-GGA-1250347); (R-GGA-167044); (R-GGA-180336); (R-GGA-201556); (R-GGA-210993); (R-GGA-2424491); (R-GGA-2428933); (R-GGA-2730905); (R-GGA-2871796); (R-GGA-2871809); (R-GGA-354192); (R-GGA-512988); (R-GGA-5654688); (R-GGA-5654699); (R-GGA-5654704); (R-GGA-5654719); (R-GGA-5673001); (R-GGA-74749); (R-GGA-74751); (R-GGA-8851805); (R-GGA-8853659); (R-GGA-8983432); (R-GGA-9009391); (R-GGA-912526); (R-GGA-9634597); (R-GGA-9842663)", "pathway_count": 28, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.179913.1, SRR13267655.229537.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000351.1. On Jun 6, 2014 this sequence version replaced XP_004948322.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005158 insulin receptor binding;GO:0046875 ephrin receptor binding;GO:0005159 insulin-like growth factor receptor binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007507 heart development;GO:0035556 intracellular signal transduction;GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYP8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYR7-1", "uniprot_id": [ { "id": "A0A1D5NYR7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYR7", "type": "external" } ], "mass": 84846.0, "length": 767, "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "organism": "Chicken", "refseq_name": "cyclin-D-binding Myb-like transcription factor 1", "refseq_ac": [ { "id": "NP_001074332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074332", "type": "external" } ], "gene_names_uniprotkb": "DMTF1; RCJMB04_9c4", "gene_names_refseq": "DMTF1", "protein_names_uniprotkb": "Cyclin-D-binding Myb-like transcription factor 1", "protein_names_refseq": "cyclin-D-binding Myb-like transcription factor 1", "tax_id": 9031, "disease": "", "pathway": " (gga:418646)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15642098", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.14846.1, SRR13267658.7970.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000011.1. On Aug 10, 2010 this sequence version replaced NP_001074332.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1D5NYR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYU5-1", "uniprot_id": [ { "id": "A0A1D5NYU5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYU5", "type": "external" } ], "mass": 12336.0, "length": 104, "protein_name": "SRA stem-loop interacting RNA binding protein", "gene_name": "SLIRP", "organism": "Chicken", "refseq_name": "SRA stem-loop-interacting RNA-binding protein, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_001235249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235249", "type": "external" } ], "gene_names_uniprotkb": "SLIRP", "gene_names_refseq": "SLIRP", "protein_names_uniprotkb": "SRA stem-loop interacting RNA binding protein", "protein_names_refseq": "SRA stem-loop-interacting RNA-binding protein, mitochondrial isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:772054)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0048471 perinuclear region of cytoplasm;GO:0001669 acrosomal vesicle;GO:0036126 sperm flagellum;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0007286 spermatid development;GO:0007338 single fertilization;GO:0007005 mitochondrion organization;GO:0000961 negative regulation of mitochondrial RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYU5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NYZ9-1", "uniprot_id": [ { "id": "A0A1D5NYZ9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NYZ9", "type": "external" } ], "mass": 38982.0, "length": 354, "protein_name": "Acrosin", "gene_name": "ACR", "organism": "Chicken", "refseq_name": "acrosin", "refseq_ac": [ { "id": "XP_003640366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640366", "type": "external" } ], "gene_names_uniprotkb": "ACR", "gene_names_refseq": "ACR", "protein_names_uniprotkb": "Acrosin", "protein_names_refseq": "acrosin", "tax_id": 9031, "disease": "", "pathway": " (gga:426864)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_003640366.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1L7NQ82", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0007340 acrosome reaction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NYZ9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ00-1", "uniprot_id": [ { "id": "A0A1D5NZ00_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ00", "type": "external" } ], "mass": 69806.0, "length": 652, "protein_name": "Sec1 family domain containing 2", "gene_name": "SCFD2", "organism": "Chicken", "refseq_name": "sec1 family domain-containing protein 2 isoform X1", "refseq_ac": [ { "id": "XP_001233406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233406", "type": "external" } ], "gene_names_uniprotkb": "SCFD2", "gene_names_refseq": "SCFD2", "protein_names_uniprotkb": "Sec1 family domain containing 2", "protein_names_refseq": "sec1 family domain-containing protein 2 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:770088)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001233406.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZ00-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ09-1", "uniprot_id": [ { "id": "A0A1D5NZ09_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ09", "type": "external" } ], "mass": 86954.0, "length": 800, "protein_name": "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "gene_name": "PNPT1", "organism": "Chicken", "refseq_name": "polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_419282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419282", "type": "external" } ], "gene_names_uniprotkb": "PNPT1", "gene_names_refseq": "PNPT1", "protein_names_uniprotkb": "Polyribonucleotide nucleotidyltransferase 1, mitochondrial; 2.7.7.8; Polynucleotide phosphorylase 1", "protein_names_refseq": "polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:421206)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_419282.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0035198 miRNA binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0004654 polyribonucleotide nucleotidyltransferase activity;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0043457 regulation of cellular respiration;GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process;GO:0000964 mitochondrial RNA 5'-end processing;GO:0006397 mRNA processing;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZ09-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ26-1", "uniprot_id": [ { "id": "A0A1D5NZ26_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ26", "type": "external" } ], "mass": 72703.0, "length": 638, "protein_name": "Grainyhead like transcription factor 1", "gene_name": "GRHL1", "organism": "Chicken", "refseq_name": "grainyhead-like protein 1 homolog isoform X1", "refseq_ac": [ { "id": "XP_015131563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131563", "type": "external" } ], "gene_names_uniprotkb": "GRHL1", "gene_names_refseq": "GRHL1", "protein_names_uniprotkb": "Grainyhead like transcription factor 1", "protein_names_refseq": "grainyhead-like protein 1 homolog isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:428651)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0031490 chromatin DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0061436 establishment of skin barrier;GO:0045616 regulation of keratinocyte differentiation;GO:0002934 desmosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZ26-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ72-1", "uniprot_id": [ { "id": "A0A1D5NZ72_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ72", "type": "external" } ], "mass": 65264.0, "length": 582, "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "TRAFD1", "organism": "Chicken", "refseq_name": "TRAF-type zinc finger domain-containing protein 1", "refseq_ac": [ { "id": "NP_001006191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006191", "type": "external" } ], "gene_names_uniprotkb": "TRAFD1", "gene_names_refseq": "TRAFD1", "protein_names_uniprotkb": "TRAF-type zinc finger domain-containing protein 1", "protein_names_refseq": "TRAF-type zinc finger domain-containing protein 1", "tax_id": 9031, "disease": "", "pathway": " (gga:416884)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ719409.1, SRR13267649.9659.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Mar 18, 2015 this sequence version replaced NP_001006191.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0045824 negative regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZ72-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ79-1", "uniprot_id": [ { "id": "A0A1D5NZ79_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ79", "type": "external" } ], "mass": 19453.0, "length": 178, "protein_name": "Ornithine decarboxylase antizyme 2", "gene_name": "OAZ2", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "OAZ2", "gene_names_refseq": "", "protein_names_uniprotkb": "Ornithine decarboxylase antizyme 2", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-350562); (R-GGA-351202)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008073 ornithine decarboxylase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:1902268 negative regulation of polyamine transmembrane transport;GO:0090316 positive regulation of intracellular protein transport;GO:0045732 positive regulation of protein catabolic process;GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZ79-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ82-1", "uniprot_id": [ { "id": "A0A1D5NZ82_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ82", "type": "external" } ], "mass": 123937.0, "length": 1109, "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif, 10", "gene_name": "ADAMTS10", "organism": "Chicken", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor", "refseq_ac": [ { "id": "NP_001376576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376576", "type": "external" } ], "gene_names_uniprotkb": "ADAMTS10", "gene_names_refseq": "ADAMTS10", "protein_names_uniprotkb": "ADAM metallopeptidase with thrombospondin type 1 motif, 10", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-5173214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000375.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZ82-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZ94-1", "uniprot_id": [ { "id": "A0A1D5NZ94_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZ94", "type": "external" } ], "mass": 60314.0, "length": 543, "protein_name": "Photopigment melanopsin-like", "gene_name": "OPN4-1", "organism": "Chicken", "refseq_name": "photopigment melanopsin-like", "refseq_ac": [ { "id": "NP_001384890", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384890", "type": "external" } ], "gene_names_uniprotkb": "OPN4-1", "gene_names_refseq": "OPN4-1S; OPN4-1; OPN4x; cOPN4-1L; cOPN4-1S", "protein_names_uniprotkb": "Photopigment melanopsin-like", "protein_names_refseq": "melanopsin 1; photopigment melanopsin-like; putative photopigment melanopsin", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16217736;17977531", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992482, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Dec 6, 2021 this sequence version replaced XP_040554628.1., [RefSeq]; Two types of melanopsin transcripts are expressed in the developing chicken retina, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008020 G protein-coupled photoreceptor activity;GO:0004930 G protein-coupled receptor activity;GO:0009881 photoreceptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007601 visual perception;GO:0007602 phototransduction;GO:0071482 cellular response to light stimulus;GO:0016037 light absorption", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A1D5NZ94-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZC4-1", "uniprot_id": [ { "id": "A0A1D5NZC4_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZC4", "type": "external" } ], "mass": 41527.0, "length": 385, "protein_name": "E3 ubiquitin-protein ligase RNF126", "gene_name": "RNF126", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RNF126", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF126; 2.3.2.27; RING finger protein 126", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005154 epidermal growth factor receptor binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0042147 retrograde transport, endosome to Golgi;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZC4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZD1-1", "uniprot_id": [ { "id": "A0A1D5NZD1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZD1", "type": "external" } ], "mass": 27446.0, "length": 244, "protein_name": "Transmembrane protein 136 family member 1", "gene_name": "TMEM136-1", "organism": "Chicken", "refseq_name": "transmembrane protein 136 family member 1", "refseq_ac": [ { "id": "NP_001304665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304665", "type": "external" } ], "gene_names_uniprotkb": "TMEM136-1", "gene_names_refseq": "TMEM136-1; TMEM136", "protein_names_uniprotkb": "Transmembrane protein 136 family member 1", "protein_names_refseq": "transmembrane protein 136 family member 1", "tax_id": 9031, "disease": "", "pathway": " (gga:419753)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.118761.1, BM440371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738216, SAMN02738218 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000341.1. On Dec 5, 2015 this sequence version replaced XP_417891.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZD1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZE1-1", "uniprot_id": [ { "id": "A0A1D5NZE1_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZE1", "type": "external" } ], "mass": 55755.0, "length": 495, "protein_name": "Cytidine and dCMP deaminase domain-containing protein 1", "gene_name": "CDADC1", "organism": "Chicken", "refseq_name": "cytidine and dCMP deaminase domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_417059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417059", "type": "external" } ], "gene_names_uniprotkb": "CDADC1", "gene_names_refseq": "CDADC1", "protein_names_uniprotkb": "Cytidine and dCMP deaminase domain-containing protein 1; 3.5.4.12; 3.5.4.5; Cytidine deaminase; dCMP deaminase", "protein_names_refseq": "cytidine and dCMP deaminase domain-containing protein 1 isoform X1", "tax_id": 9031, "disease": "", "pathway": " (gga:418864)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.5.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.12", "type": "external" } ], "go_molecular_function": "GO:0061676 importin-alpha family protein binding;GO:0004126 cytidine deaminase activity;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0004132 dCMP deaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070383 DNA cytosine deamination;GO:0009165 nucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZE1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1D5NZH5-1", "uniprot_id": [ { "id": "A0A1D5NZH5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A1D5NZH5", "type": "external" } ], "mass": 88186.0, "length": 777, "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "FHIP2A", "organism": "Chicken", "refseq_name": "FHF complex subunit HOOK interacting protein 2A isoform X2", "refseq_ac": [ { "id": "XP_015144419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144419", "type": "external" } ], "gene_names_uniprotkb": "FHIP2A", "gene_names_refseq": "FHIP2A", "protein_names_uniprotkb": "FHF complex subunit HOOK interacting protein 2A", "protein_names_refseq": "FHF complex subunit HOOK interacting protein 2A isoform X2", "tax_id": 9031, "disease": "", "pathway": " (gga:423912)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1D5NZH5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true } ]