[ { "uniprot_canonical_ac": "A0A0G2K1A9-1", "uniprot_id": [ { "id": "A0A0G2K1A9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A9", "type": "external" } ], "mass": 80916.0, "length": 723, "protein_name": "Nucleolar protein 11", "gene_name": "Nol11", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nol11", "gene_names_refseq": "", "protein_names_uniprotkb": "Nucleolar protein 11", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6791226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0034455 t-UTP complex", "go_biological_process": "GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1A9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1B1-1", "uniprot_id": [ { "id": "A0A0G2K1B1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1B1", "type": "external" } ], "mass": 19145.0, "length": 177, "protein_name": "Zinc finger protein 428", "gene_name": "Zfp428", "organism": "Rat", "refseq_name": "zinc finger protein 428 isoform b", "refseq_ac": [ { "id": "NP_001101946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101946", "type": "external" } ], "gene_names_uniprotkb": "Zfp428", "gene_names_refseq": "RGD1564862; Zfp428", "protein_names_uniprotkb": "Zinc finger protein 428", "protein_names_refseq": "zinc finger protein 428 isoform b", "tax_id": 10116, "disease": "", "pathway": " (rno:361519)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1B1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1B7-1", "uniprot_id": [ { "id": "A0A0G2K1B7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1B7", "type": "external" } ], "mass": 39899.0, "length": 355, "protein_name": "NEDD4 binding protein 2-like 1", "gene_name": "N4bp2l1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "N4bp2l1", "gene_names_refseq": "", "protein_names_uniprotkb": "NEDD4 binding protein 2-like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1B7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1C4-1", "uniprot_id": [ { "id": "A0A0G2K1C4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1C4", "type": "external" } ], "mass": 75093.0, "length": 649, "protein_name": "Zinc finger protein 799", "gene_name": "Zfp799", "organism": "Rat", "refseq_name": "zinc finger protein 799", "refseq_ac": [ { "id": "NP_001009537", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009537", "type": "external" } ], "gene_names_uniprotkb": "Zfp799", "gene_names_refseq": "Zfp799; Zpf799", "protein_names_uniprotkb": "Zinc finger protein 799", "protein_names_refseq": "zinc finger protein 799", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-212436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1C4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1D2-1", "uniprot_id": [ { "id": "A0A0G2K1D2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1D2", "type": "external" } ], "mass": 65945.0, "length": 607, "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1", "gene_name": "Rap1gds1", "organism": "Rat", "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1 isoform 1", "refseq_ac": [ { "id": "NP_001401991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401991", "type": "external" } ], "gene_names_uniprotkb": "Rap1gds1", "gene_names_refseq": "Rap1gds1", "protein_names_uniprotkb": "Rap1 GTPase-GDP dissociation stimulator 1", "protein_names_refseq": "RAP1, GTP-GDP dissociation stimulator 1; rap1 GTPase-GDP dissociation stimulator 1 isoform 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "16954223;18348285;18683930;20190816;23155002", "class_list": "", "function": "ALK activation of Rap1 via the Rap1-specific GEF C3Gmay contribute to cell proliferation and oncogenesis of neuroblastoma., [RefSeq, PubMed]; Acts as a GEF (guanine nucleotide exchange factor) for prenylated RHOA. Acts as a GEF for RHOC. Chaperones the downstream trafficking and/or processing of small newly prenylated GTPases. Escorts RAC1 to the nucleus., [UniProtKB, UniProtKB]; Acts as a GEF (guanine nucleotide exchange factor) for the Rho family of small GTP-binding proteins (G proteins) that stimulates the dissociation of GDP to enable subsequent binding of GTP. Additionally, appears to chaperone the processing and/or trafficking of small GTPases containing a C-terminal polybasic region independently of GEF activity. Targets include RAP1A/RAP1B, RHOA, RHOB, RHOC, RAC1 and KRAS. Regulates mitochondrial dynamics by controlling RHOT function to promote mitochondrial fission during high calcium conditions. Able to promote the Ca(2+) release from the endoplasmic reticulum via both inositol trisphosphate (Ins3P) and ryanodine sensitive receptors leading to a enhanced mitochondrial Ca(2+) uptake., [UniProtKB, UniProtKB]; BetaPak-interacting exchange factor-mediated Rac1 activation requires smgGDS guanine nucleotide exchange factor in basic fibroblast growth factor-induced neurite outgrowth, [RefSeq, PubMed]; SmgGDS, a novel Ras regulator, suppresses Ras-BPGAP1-induced Ras/ERK activation., [RefSeq, PubMed]; These results identify SmgGDS as a novel regulator of myosin organization and contraction in vascular smooth muscle cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0086098 angiotensin-activated signaling pathway involved in heart process;GO:0031034 myosin filament assembly;GO:0003300 cardiac muscle hypertrophy;GO:0014829 vascular associated smooth muscle contraction;GO:0034504 protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0G2K1D2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1E3-1", "uniprot_id": [ { "id": "A0A0G2K1E3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1E3", "type": "external" } ], "mass": 294918.0, "length": 2714, "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "Kmt2b", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase 2B", "refseq_ac": [ { "id": "NP_001414070", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414070", "type": "external" } ], "gene_names_uniprotkb": "Kmt2b", "gene_names_refseq": "Kmt2b; Mll4; RGD1308331; Wbp7", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase 2B; 2.1.1.364; Trithorax homolog 2; WW domain-binding protein 7", "protein_names_refseq": "WW domain binding protein 7; histone-lysine N-methyltransferase 2B-like; histone-lysine N-methyltransferase 2B; lysine (K)-specific methyltransferase 2B; myeloid/lymphoid or mixed-lineage leukemia 4", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); dystonia 28, childhood-onset (Disease Ontology:DOID:0060936); autosomal dominant intellectual developmental disorder 68 (Disease Ontology:DOID:0061041); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (R-RNO-201722); (R-RNO-3214841); (R-RNO-3769402); (R-RNO-8936459); (R-RNO-9772755)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "22673903;36162497;38876442", "class_list": "", "function": "Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress., [RefSeq, PubMed]; Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2C in enriching H3K4me1 marks on primed and active enhancer elements. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation., [UniProtKB, UniProtKB, UniProtKB]; KMT2B-dependent RFK transcription activates the TNF-alpha/NOX2 pathway and enhances ferroptosis caused by myocardial ischemia-reperfusion., [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" }, { "id": "2.1.1.371", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.371", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.85", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" }, { "id": "1.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0045322 unmethylated CpG binding;GO:0140999 histone H3K4 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035097 histone methyltransferase complex;GO:0044665 MLL1/2 complex", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription;GO:0001541 ovarian follicle development;GO:0032259 methylation;GO:0048599 oocyte development;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K1E3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1E5-1", "uniprot_id": [ { "id": "A0A0G2K1E5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1E5", "type": "external" } ], "mass": 154865.0, "length": 1398, "protein_name": "Symplekin", "gene_name": "Sympk", "organism": "Rat", "refseq_name": "symplekin", "refseq_ac": [ { "id": "NP_001402715", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402715", "type": "external" } ], "gene_names_uniprotkb": "Sympk", "gene_names_refseq": "Hfn3g; Sympk", "protein_names_uniprotkb": "Symplekin", "protein_names_refseq": "hepatocyte nuclear factor 3 gamma; symplekin", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-159231); (R-RNO-73856); (R-RNO-77595); (R-RNO-9770562)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0097165 nuclear stress granule;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006397 mRNA processing;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K1E5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1F7-1", "uniprot_id": [ { "id": "A0A0G2K1F7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7", "type": "external" } ], "mass": 395569.0, "length": 3512, "protein_name": "Unconventional myosin-XV", "gene_name": "Myo15a", "organism": "Rat", "refseq_name": "unconventional myosin-XV", "refseq_ac": [ { "id": "NP_001414755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414755", "type": "external" } ], "gene_names_uniprotkb": "Myo15a", "gene_names_refseq": "Myo15a; Myo15; RGD1561873", "protein_names_uniprotkb": "Unconventional myosin-XV; Unconventional myosin-15", "protein_names_refseq": "myosin XV; unconventional myosin-XV-like; unconventional myosin-XV", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 3 (Disease Ontology:DOID:0110488); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "14629112;21479269", "class_list": "", "function": "Mutations in binding domains of myosin XV do not only cause non-syndromic hearing loss but can also lead to syndromic disorders including retinal dysfunction. Publication Status: Online-Only, [RefSeq, PubMed]; Myo15 and Kcnj12 can be regarded as candidate genes for the deafblind phenotype of the LEW-ci2 rat., [RefSeq, PubMed]; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032421 stereocilium bundle;GO:0032420 stereocilium;GO:0016459 myosin complex;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0007626 locomotory behavior;GO:0042472 inner ear morphogenesis;GO:0007605 sensory perception of sound;GO:0009416 response to light stimulus;GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K1F7-1", "record_type": "protein", "filter_code": "0000000.0000110.001000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1F8-1", "uniprot_id": [ { "id": "A0A0G2K1F8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F8", "type": "external" } ], "mass": 24503.0, "length": 225, "protein_name": "Membrane spanning 4-domains A7", "gene_name": "Ms4a7", "organism": "Rat", "refseq_name": "membrane-spanning 4-domains subfamily A member 7", "refseq_ac": [ { "id": "NP_001397220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001397220", "type": "external" } ], "gene_names_uniprotkb": "Ms4a7", "gene_names_refseq": "Ms4a7", "protein_names_uniprotkb": "Membrane spanning 4-domains A7", "protein_names_refseq": "membrane-spanning 4-domains subfamily A member 7; membrane-spanning 4-domains, subfamily A, member 7", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005802 trans-Golgi network", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1F8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1G4-1", "uniprot_id": [ { "id": "A0A0G2K1G4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1G4", "type": "external" } ], "mass": 64341.0, "length": 576, "protein_name": "Ring finger and SPRY domain containing 1", "gene_name": "Rspry1", "organism": "Rat", "refseq_name": "RING finger and SPRY domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_038953925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038953925", "type": "external" } ], "gene_names_uniprotkb": "Rspry1", "gene_names_refseq": "RGD1308847; Rspry1", "protein_names_uniprotkb": "Ring finger and SPRY domain containing 1", "protein_names_refseq": "RING finger and SPRY domain-containing protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1G4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1G6-1", "uniprot_id": [ { "id": "A0A0G2K1G6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1G6", "type": "external" } ], "mass": 20308.0, "length": 176, "protein_name": "Ferritin", "gene_name": "Fthl17b", "organism": "Rat", "refseq_name": "ferritin, heavy polypeptide-like 17, member B", "refseq_ac": [ { "id": "NP_001103837", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103837", "type": "external" } ], "gene_names_uniprotkb": "Fthl17b; Fthl17cl1; LOC120099271; LOC691895", "gene_names_refseq": "Fthl17b", "protein_names_uniprotkb": "Ferritin", "protein_names_refseq": "ferritin, heavy polypeptide-like 17, member B", "tax_id": 10116, "disease": "candidiasis (Disease Ontology:DOID:1508)", "pathway": " (rno:691895)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0008199 ferric iron binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1G6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1H6-1", "uniprot_id": [ { "id": "A0A0G2K1H6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1H6", "type": "external" } ], "mass": 65211.0, "length": 556, "protein_name": "Zinc finger protein 939", "gene_name": "Zfp939", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp939", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 939", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:690136)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1H6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1I1-1", "uniprot_id": [ { "id": "A0A0G2K1I1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1I1", "type": "external" } ], "mass": 64697.0, "length": 572, "protein_name": "WSC domain containing 2", "gene_name": "Wscd2", "organism": "Rat", "refseq_name": "sialate:O-sulfotransferase 2", "refseq_ac": [ { "id": "NP_001258107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258107", "type": "external" } ], "gene_names_uniprotkb": "Wscd2", "gene_names_refseq": "Wscd2-ps1; 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1N7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1P3-1", "uniprot_id": [ { "id": "A0A0G2K1P3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1P3", "type": "external" } ], "mass": 38323.0, "length": 331, "protein_name": "BCL2 interacting protein 2", "gene_name": "Bnip2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bnip2", "gene_names_refseq": "", "protein_names_uniprotkb": "BCL2 interacting protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-525793)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005814 centriole", "go_biological_process": "GO:0001824 blastocyst development;GO:0051057 positive regulation of small GTPase mediated signal transduction;GO:0043410 positive regulation of MAPK cascade;GO:0045666 positive regulation of neuron differentiation;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K1P3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1Q0-1", "uniprot_id": [ { "id": "A0A0G2K1Q0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1Q0", "type": "external" } ], "mass": 184533.0, "length": 1633, "protein_name": "Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta", "gene_name": "Pik3c2b", "organism": "Rat", "refseq_name": "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform 1", "refseq_ac": [ { "id": "NP_001423992", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423992", "type": "external" } ], "gene_names_uniprotkb": "Pik3c2b", "gene_names_refseq": "Pik3c2b", "protein_names_uniprotkb": "Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta", "protein_names_refseq": "nuclear cap binding protein subunit 2; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform 1; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; phosphoinositide-3-kinase, class 2, beta polypeptide", "tax_id": 10116, "disease": "", "pathway": " (rno:289021); (R-RNO-1660499)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "16857245;29393594;29492791", "class_list": "", "function": "Activated during compensatory liver growth, which clearly demonstrates that different class II PI3K enzymes have different subnuclear localization., [RefSeq, PubMed]; Missense single-nucleotide polymorphism in the Pik3c2b gene associated with autophagy regulation in in the progression of Age-related macular degeneration was found., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" } ], "go_molecular_function": "GO:0001727 lipid kinase activity;GO:0005524 ATP binding;GO:0035091 phosphatidylinositol binding;GO:0016303 1-phosphatidylinositol-3-kinase activity;GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0030139 endocytic vesicle;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0016236 macroautophagy;GO:0009267 cellular response to starvation;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:1905037 autophagosome organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K1Q0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1Q8-1", "uniprot_id": [ { "id": "ABCA3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1Q8", "type": "external" } ], "mass": 191767.0, "length": 1704, "protein_name": "Phospholipid-transporting ATPase ABCA3", "gene_name": "Abca3", "organism": "Rat", "refseq_name": "phospholipid-transporting ATPase ABCA3", "refseq_ac": [ { "id": "NP_001382963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382963", "type": "external" } ], "gene_names_uniprotkb": "Abca3", "gene_names_refseq": "Abca3", "protein_names_uniprotkb": "Phospholipid-transporting ATPase ABCA3; 7.6.2.1; 7.6.2.2; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3", "protein_names_refseq": "ATP-binding cassette sub-family A member 3; ATP-binding cassette, sub-family A (ABC1), member 3; ATP-binding cassette, subfamily A (ABC1), member 3; phospholipid-transporting ATPase ABCA3; xenobiotic-transporting ATPase ABCA3", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); neonatal respiratory failure (Disease Ontology:DOID:11161); respiratory failure (Disease Ontology:DOID:11162); pulmonary alveolar proteinosis (Disease Ontology:DOID:12120); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); interstitial lung disease (Disease Ontology:DOID:3082); lung disease (Disease Ontology:DOID:850)", "pathway": " (R-RNO-1369062); (R-RNO-5683826)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "11940594;15369786;38843836", "class_list": "", "function": "Catalyzes the ATP-dependent transport of phospholipids such as phosphatidylcholine and phosphoglycerol from the cytoplasm into the lumen side of lamellar bodies, in turn participates in the lamellar bodies biogenesis and homeostasis of pulmonary surfactant. Transports preferentially phosphatidylcholine containing short acyl chains. In addition plays a role as an efflux transporter of miltefosine across macrophage membranes and free cholesterol (FC) through intralumenal vesicles by removing FC from the cell as a component of surfactant and protects cells from free cholesterol toxicity., [UniProtKB, UniProtKB]; Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3., [RefSeq, PubMed]; These findings demonstrate that glucocorticoid-induced up-regulation of ABCA3 expression in vivo is mediated by transcriptional activation through the GRE in the promoter., [RefSeq, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 8, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043231 intracellular membrane-bounded organelle;GO:0005765 lysosomal membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0005770 late endosome", "go_biological_process": "GO:0032368 regulation of lipid transport;GO:0006869 lipid transport;GO:0010875 positive regulation of cholesterol efflux;GO:0043129 surfactant homeostasis;GO:0030324 lung development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K1Q8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0100000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1R0-1", "uniprot_id": [ { "id": "A0A0G2K1R0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1R0", "type": "external" } ], "mass": 125874.0, "length": 1094, "protein_name": "Axonemal dynein light chain domain containing 1", "gene_name": "Axdnd1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Axdnd1", "gene_names_refseq": "", "protein_names_uniprotkb": "Axonemal dynein light chain domain containing 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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0.1, "record_id": "A0A0G2K1R0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1R2-1", "uniprot_id": [ { "id": "A0A0G2K1R2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1R2", "type": "external" } ], "mass": 33545.0, "length": 305, "protein_name": "B-cell CLL/lymphoma 7 protein family member A", "gene_name": "Bcl7a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bcl7a", "gene_names_refseq": "", "protein_names_uniprotkb": "B-cell CLL/lymphoma 7 protein family member A", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-9933937); (R-RNO-9933939); (R-RNO-9933946); (R-RNO-9933947); (R-RNO-9934037)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016514 SWI/SNF complex", "go_biological_process": "GO:0140058 neuron projection arborization;GO:0061744 motor behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1R2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1R3-1", "uniprot_id": [ { "id": "A0A0G2K1R3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1R3", "type": "external" } ], "mass": 103093.0, "length": 929, "protein_name": "Scaffold protein involved in DNA repair", "gene_name": "Spidr", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Spidr; RGD1566036", "gene_names_refseq": "", "protein_names_uniprotkb": "Scaffold protein involved in DNA repair", "protein_names_refseq": "", "tax_id": 10116, "disease": "ovarian dysgenesis 9 (Disease 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"external" } ], "mass": 58037.0, "length": 531, "protein_name": "Eyes absent homolog", "gene_name": "Eya2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Eya2", "gene_names_refseq": "", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "", "tax_id": 10116, "disease": "branchiootorenal syndrome (Disease Ontology:DOID:14702); eye disease (Disease Ontology:DOID:5614)", "pathway": " (R-RNO-5693565)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004725 protein tyrosine phosphatase activity;GO:0140793 histone H2AXY142 phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0014706 striated muscle tissue development;GO:0006281 DNA repair;GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair;GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1T5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1T7-1", "uniprot_id": [ { "id": "A0A0G2K1T7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1T7", "type": "external" } ], "mass": 69063.0, "length": 625, "protein_name": "Basic helix-loop-helix ARNT like 2", "gene_name": "Bmal2", "organism": "Rat", "refseq_name": "basic helix-loop-helix ARNT-like protein 2 isoform X2", "refseq_ac": [ { "id": "XP_038963873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038963873", "type": "external" } ], "gene_names_uniprotkb": "Bmal2; Arntl2", "gene_names_refseq": "Arnt4; Arntl2; Bmal2", "protein_names_uniprotkb": "Basic helix-loop-helix ARNT like 2", "protein_names_refseq": "basic helix-loop-helix ARNT-like protein 2 isoform X2", "tax_id": 10116, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); hypertension (Disease Ontology:DOID:10763); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1V3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1V7-1", "uniprot_id": [ { "id": "A0A0G2K1V7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1V7", "type": "external" } ], "mass": 38988.0, "length": 354, "protein_name": "Beta-sarcoglycan", "gene_name": "Sgcb", "organism": "Rat", "refseq_name": "beta-sarcoglycan isoform X1", "refseq_ac": [ { "id": "XP_063129669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063129669", "type": "external" } ], "gene_names_uniprotkb": "Sgcb", "gene_names_refseq": "Sgcb", "protein_names_uniprotkb": "Beta-sarcoglycan", "protein_names_refseq": "beta-sarcoglycan isoform X1", "tax_id": 10116, "disease": "autosomal recessive limb-girdle muscular dystrophy type 2E (Disease Ontology:DOID:0110279); 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DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella. 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dry eye syndrome (Disease Ontology:DOID:10140); otitis media (Disease Ontology:DOID:10754); gastric ulcer (Disease Ontology:DOID:10808); Sjogren's syndrome (Disease Ontology:DOID:12894); angle-closure glaucoma (Disease Ontology:DOID:13550); cystic fibrosis (Disease Ontology:DOID:1485); cystitis (Disease Ontology:DOID:1679); glaucoma (Disease Ontology:DOID:1686); pancreatic cancer (Disease Ontology:DOID:1793); asthma (Disease Ontology:DOID:2841); mucinous adenocarcinoma (Disease Ontology:DOID:3030); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); pulmonary fibrosis (Disease Ontology:DOID:3770); allergic rhinitis (Disease Ontology:DOID:4481); rhinitis (Disease Ontology:DOID:4483); common bile duct neoplasm (Disease Ontology:DOID:4608); cholangiocarcinoma (Disease Ontology:DOID:4947); stomach disease (Disease Ontology:DOID:76); corneal ulcer (Disease Ontology:DOID:8463); keratoconjunctivitis (Disease Ontology:DOID:9368)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0070701 mucus layer;GO:0005615 extracellular space", "go_biological_process": "GO:0010477 response to sulfur dioxide;GO:0030855 epithelial cell differentiation;GO:0032496 response to lipopolysaccharide;GO:0071300 cellular response to retinoic acid;GO:0033189 response to vitamin A", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1Y4-1", "record_type": "protein", "filter_code": "0000000.1000010.001000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1Y9-1", "uniprot_id": [ { "id": "A0A0G2K1Y9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1Y9", "type": "external" } ], "mass": 144291.0, "length": 1312, "protein_name": "ALF transcription elongation factor 2", "gene_name": "Aff2", "organism": "Rat", "refseq_name": "AF4/FMR2 family member 2", "refseq_ac": [ { "id": "NP_001414217", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414217", "type": "external" } ], "gene_names_uniprotkb": "Aff2", "gene_names_refseq": "Aff2; 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Or8g4", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1321; olfactory receptor Olr1321; olfactory receptor gene Olr1321", "tax_id": 10116, "disease": "", "pathway": " (rno:405076)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1Z4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K222-1", "uniprot_id": [ { "id": "A0A0G2K222_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K222", "type": "external" } ], "mass": 78737.0, "length": 702, "protein_name": "mRNA export factor GLE1", "gene_name": "Gle1-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gle1-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "mRNA export factor GLE1; GLE1 RNA export mediator; GLE1-like protein; Nucleoporin GLE1", "protein_names_refseq": "", "tax_id": 10116, "disease": "lethal congenital contracture syndrome 1 (Disease Ontology:DOID:0060559)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0000822 inositol hexakisphosphate binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0044614 nuclear pore cytoplasmic filaments", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K222-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K228-1", "uniprot_id": [ { "id": "A0A0G2K228_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K228", "type": "external" } ], "mass": 49771.0, "length": 448, "protein_name": "Zinc finger and BTB domain containing 25", "gene_name": "Zbtb25", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zbtb25", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 25", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:314245)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K228-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K230-1", "uniprot_id": [ { "id": "A0A0G2K230_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K230", "type": "external" } ], "mass": 100721.0, "length": 900, "protein_name": "Desmocollin 3", "gene_name": "Dsc3", "organism": "Rat", "refseq_name": "desmocollin-3", "refseq_ac": [ { "id": "NP_001100872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100872", "type": "external" } ], "gene_names_uniprotkb": "Dsc3", "gene_names_refseq": "Dsc3", "protein_names_uniprotkb": "Desmocollin 3", "protein_names_refseq": "desmocollin-3", "tax_id": 10116, "disease": "arrhythmogenic right ventricular cardiomyopathy (Disease Ontology:DOID:0050431)", "pathway": " (rno:307563); (R-RNO-6805567); (R-RNO-6809371)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZZI6", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:1990782 protein tyrosine kinase binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030057 desmosome", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0001701 in utero embryonic development;GO:0098609 cell-cell adhesion;GO:0007416 synapse assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K230-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K247-1", "uniprot_id": [ { "id": "A0A0G2K247_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K247", "type": "external" } ], "mass": 51068.0, "length": 451, "protein_name": "Protein kinase cAMP-dependent X-linked catalytic subunit", "gene_name": "Prkx", "organism": "Rat", "refseq_name": "cAMP-dependent protein kinase catalytic subunit PRKX", "refseq_ac": [ { "id": "NP_001029135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029135", "type": "external" } ], "gene_names_uniprotkb": "Prkx", "gene_names_refseq": "Prkx", "protein_names_uniprotkb": "Protein kinase cAMP-dependent X-linked catalytic subunit", "protein_names_refseq": "cAMP-dependent protein kinase catalytic subunit PRKX; protein kinase, X-linked; serine/threonine-protein kinase PRKX", "tax_id": 10116, "disease": "", "pathway": " (rno:501563)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "GO:0060562 epithelial tube morphogenesis;GO:2000696 regulation of epithelial cell differentiation involved in kidney development;GO:0060993 kidney morphogenesis;GO:0001525 angiogenesis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K247-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K254-1", "uniprot_id": [ { "id": "A0A0G2K254_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K254", "type": "external" } ], "mass": 73605.0, "length": 641, "protein_name": "Kinetochore protein NDC80", "gene_name": "Ndc80", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ndc80", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinetochore protein NDC80", "protein_names_refseq": "", "tax_id": 10116, "disease": "stomach cancer (Disease Ontology:DOID:10534); cancer (Disease Ontology:DOID:162); lung non-small cell carcinoma (Disease Ontology:DOID:3908); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (R-RNO-141430); (R-RNO-141444); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-5663220); (R-RNO-68877); (R-RNO-9648025)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0030332 cyclin binding;GO:0140483 kinetochore adaptor activity", "go_cellular_component": "GO:0031262 Ndc80 complex;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0051310 metaphase chromosome alignment;GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0051383 kinetochore organization;GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K254-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K261-1", "uniprot_id": [ { "id": "A0A0G2K261_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K261", "type": "external" } ], "mass": 109987.0, "length": 986, "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "Iars2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Iars2", "gene_names_refseq": "", "protein_names_uniprotkb": "Isoleucine--tRNA ligase, mitochondrial; 6.1.1.5; Isoleucyl-tRNA synthetase", "protein_names_refseq": "", "tax_id": 10116, "disease": "mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (R-RNO-9837999)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile))., [UniProtKB, UniProtKB]", "predicted_glycosites": 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "5.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7", "type": "external" }, { "id": "2.7.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.23", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "2.7.11.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.2", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004822 isoleucine-tRNA ligase activity;GO:0005524 ATP binding;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006428 isoleucyl-tRNA aminoacylation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K261-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K269-1", "uniprot_id": [ { "id": "A0A0G2K269_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K269", "type": "external" } ], "mass": 49816.0, "length": 452, "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "gene_name": "Dph1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dph1", "gene_names_refseq": "", "protein_names_uniprotkb": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; 2.5.1.108; Diphthamide biosynthesis protein 1; Diphtheria toxin resistance protein 1; Ovarian cancer-associated gene 1 protein homolog; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Miller-Dieker lissencephaly syndrome (Disease Ontology:DOID:0060469); diphthamide deficiency syndrome (Disease Ontology:DOID:0070476); diphthamide deficiency syndrome 1 (Disease Ontology:DOID:0070477)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.108", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051536 iron-sulfur cluster binding;GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0030054 cell junction;GO:0032991 protein-containing complex", "go_biological_process": "GO:0032526 response to retinoic acid;GO:0048144 fibroblast proliferation;GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K269-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K283-1", "uniprot_id": [ { "id": "A0A0G2K283_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K283", "type": "external" } ], "mass": 142576.0, "length": 1244, "protein_name": "ATP-dependent RNA helicase DHX8", "gene_name": "Dhx8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dhx8", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-dependent RNA helicase DHX8; 3.6.4.13; DEAH box protein 8", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-72163)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0042802 identical protein binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016604 nuclear body;GO:0071013 catalytic step 2 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K283-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K287-1", "uniprot_id": [ { "id": "A0A0G2K287_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K287", "type": "external" } ], "mass": 37753.0, "length": 329, "protein_name": "LIM domain binding 2", "gene_name": "Ldb2", "organism": "Rat", "refseq_name": "LIM domain-binding protein 2 isoform X4", "refseq_ac": [ { "id": "XP_017454598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017454598", "type": "external" } ], "gene_names_uniprotkb": "Ldb2", "gene_names_refseq": "Ldb2", "protein_names_uniprotkb": "LIM domain binding 2", "protein_names_refseq": "LIM domain-binding protein 2 isoform X4", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031252 cell leading edge;GO:0005667 transcription regulator complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030334 regulation of cell migration;GO:0001942 hair follicle development;GO:0035019 somatic stem cell population maintenance;GO:0010669 epithelial structure maintenance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K287-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K295-1", "uniprot_id": [ { "id": "A0A0G2K295_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K295", "type": "external" } ], "mass": 79095.0, "length": 705, "protein_name": "Angiogenic factor with G patch and FHA domains 1", "gene_name": "Aggf1", "organism": "Rat", "refseq_name": "angiogenic factor with G patch and FHA domains 1", "refseq_ac": [ { "id": "NP_001414708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414708", "type": "external" } ], "gene_names_uniprotkb": "Aggf1", "gene_names_refseq": "Aggf1; RGD1310888", "protein_names_uniprotkb": "Angiogenic factor with G patch and FHA domains 1; Angiogenic factor VG5Q", "protein_names_refseq": "angiogenic factor with G patch and FHA domains 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "26850475;28153879", "class_list": "", "function": "Aggf1 has a role in regulating vascular injury., [RefSeq, PubMed]; Aggf1 over-expression blocks liver fibrosis and Hepatic stellate cells (HSCs) activation. Aggf1 interacts with SMAD7 to suppress TGF signaling. DNA methylation regulates liver fibrosis and HSC activation by targeting Aggf1., [RefSeq, PubMed]; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0030154 cell differentiation;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K295-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2A4-1", "uniprot_id": [ { "id": "A0A0G2K2A4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2A4", "type": "external" } ], "mass": 83636.0, "length": 747, "protein_name": "MYB proto-oncogene, transcription factor", "gene_name": "Myb", "organism": "Rat", "refseq_name": "transcriptional activator Myb", "refseq_ac": [ { "id": "NP_001414338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414338", "type": "external" } ], "gene_names_uniprotkb": "Myb", "gene_names_refseq": "Myb; RGD1560020", "protein_names_uniprotkb": "MYB proto-oncogene, transcription factor", "protein_names_refseq": "transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog", "tax_id": 10116, "disease": "adult T-cell leukemia/lymphoma (Disease Ontology:DOID:0050523); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); essential thrombocythemia (Disease Ontology:DOID:2224); transient cerebral ischemia (Disease Ontology:DOID:224); myelofibrosis (Disease Ontology:DOID:4971)", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "22673903;31210326;33804806", "class_list": "", "function": "Embryonic-Derived Myb(-) Macrophages Enhance Bacterial Clearance and Improve Survival in Rat Sepsis. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2G2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2H0-1", "uniprot_id": [ { "id": "A0A0G2K2H0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2H0", "type": "external" } ], "mass": 97191.0, "length": 879, "protein_name": "Tyrosine-protein kinase receptor UFO", "gene_name": "Axl", "organism": "Rat", "refseq_name": "tyrosine-protein kinase receptor UFO isoform 2 precursor", "refseq_ac": [ { "id": "NP_001013165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013165", "type": "external" } ], "gene_names_uniprotkb": "Axl", "gene_names_refseq": "Axl", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor UFO; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase receptor UFO isoform 2 precursor; tyrosine-protein kinase receptor UFO", "tax_id": 10116, "disease": "glomerulonephritis (Disease Ontology:DOID:2921); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (R-RNO-4420097)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "28386842;29196212;31181097;31884887;34678434", "class_list": "", "function": "AXL signaling in primary sensory neurons contributes to chronic compression of dorsal root ganglion-induced neuropathic pain in rats., [RefSeq, PubMed]; Activation of Axl by recombinant Growth-arrest-specific protein 6 (rGas6) attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-kappaB pathway after middle cerebral artery occlusion (MCAO) in rats, [RefSeq, PubMed]; Axl expression pattern suggests a role in the early progression of LV remodeling in HF but not in the later systolic dysfunction. Publication Status: Online-Only, [RefSeq, PubMed]; The Gas6/Axl interaction was inhibited by R428, which abolished the preventive effect of VK2 on CaCl2- and beta-GP-induced apoptosis and calcification. These results suggest that Gas6 is critical in VK2-mediated functions that attenuate CaCl2- and beta-GP-induced VSMC calcification by blocking apoptosis., [RefSeq, PubMed]; Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl pathway., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, 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"type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0046872 metal ion binding;GO:0001618 virus receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001779 natural killer cell differentiation;GO:0035457 cellular response to interferon-alpha;GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:2000669 negative regulation of dendritic cell apoptotic process;GO:0046649 lymphocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K2H0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2H3-1", "uniprot_id": [ { "id": "A0A0G2K2H3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2H3", "type": "external" } ], "mass": 28693.0, "length": 253, "protein_name": "Chondrolectin", "gene_name": "Chodl", "organism": "Rat", "refseq_name": "chondrolectin isoform X1", "refseq_ac": [ { "id": "XP_006248066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248066", "type": "external" } ], "gene_names_uniprotkb": "Chodl", "gene_names_refseq": "Chodl", "protein_names_uniprotkb": "Chondrolectin", "protein_names_refseq": "chondrolectin isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0050772 positive regulation of axonogenesis;GO:0010975 regulation of neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2H3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2H4-1", "uniprot_id": [ { "id": "A0A0G2K2H4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "type": "external" } ], "mass": 110151.0, "length": 977, "protein_name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "gene_name": "Ern1", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase/endoribonuclease IRE1 precursor", "refseq_ac": [ { "id": "XP_006247696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247696", "type": "external" } ], "gene_names_uniprotkb": "Ern1", "gene_names_refseq": "Ern1; RGD1559716", "protein_names_uniprotkb": "Serine/threonine-protein kinase/endoribonuclease IRE1; 2.7.11.1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; Ire1-alpha", "protein_names_refseq": "endoplasmic reticulum (ER) to nucleus signalling 1; serine/threonine-protein kinase/endoribonuclease IRE1 precursor; serine/threonine-protein kinase/endoribonuclease IRE1", "tax_id": 10116, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684); oropharynx cancer (Disease Ontology:DOID:8557)", "pathway": " (rno:498013); (R-RNO-381070)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:1990604 IRE1-TRAF2-ASK1 complex;GO:1990630 IRE1-RACK1-PP2A complex;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0070054 mRNA splicing, via endonucleolytic cleavage and ligation;GO:1901142 insulin metabolic process;GO:0010629 negative regulation of gene expression;GO:0036498 IRE1-mediated unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2H4-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2H9-1", "uniprot_id": [ { "id": "A0A0G2K2H9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2H9", "type": "external" } ], "mass": 136423.0, "length": 1241, "protein_name": "Transcriptional regulating factor 1", "gene_name": "Trerf1", "organism": "Rat", "refseq_name": "transcriptional-regulating factor 1 isoform 1", "refseq_ac": [ { "id": "NP_001419757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419757", "type": "external" } ], "gene_names_uniprotkb": "Trerf1", "gene_names_refseq": "Trerf1", "protein_names_uniprotkb": "Transcriptional regulating factor 1", "protein_names_refseq": "transcriptional-regulating factor 1 isoform 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", 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"external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" } ], "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding;GO:0003712 transcription coregulator activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0001946 lymphangiogenesis;GO:0046825 regulation of protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K2N0-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2N3-1", "uniprot_id": [ { "id": "A0A0G2K2N3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2N3", "type": "external" } ], "mass": 50661.0, "length": 451, "protein_name": "TEA 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DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0140552 TEAD-YAP complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:1902459 positive regulation of stem cell population maintenance;GO:0007507 heart development;GO:0030307 positive regulation of cell growth;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K2N3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2P4-1", "uniprot_id": [ { "id": "A0A0G2K2P4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2P4", "type": "external" } ], "mass": 56224.0, "length": 497, "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2t1", "organism": "Rat", "refseq_name": "cytochrome P450, family 2, subfamily t, polypeptide 1", "refseq_ac": [ { "id": "NP_599196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_599196", "type": "external" } ], "gene_names_uniprotkb": "Cyp2t1", "gene_names_refseq": "Cyp2t1", "protein_names_uniprotkb": "unspecific monooxygenase; 1.14.14.1", "protein_names_refseq": "cytochrome P450 monooxygenase CYP2T1; cytochrome P450, family 2, subfamily t, polypeptide 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity;GO:0019825 oxygen binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2P4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2P5-1", "uniprot_id": [ { "id": "ZO1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "type": "external" } ], "mass": 197148.0, "length": 1765, "protein_name": "Tight junction protein ZO-1", "gene_name": "Tjp1", "organism": "Rat", "refseq_name": "tight junction protein ZO-1 isoform 1", "refseq_ac": [ { "id": "XP_063140420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063140420", "type": "external" } ], "gene_names_uniprotkb": "Tjp1", "gene_names_refseq": "Tjp1; ZO-1", "protein_names_uniprotkb": "Tight junction protein ZO-1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1", "protein_names_refseq": "tight junction protein ZO-1 isoform 1; tight junction protein ZO-1; zona occludens 1; zona occludens protein 1; zonula occludens protein 1", "tax_id": 10116, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); uveitis (Disease Ontology:DOID:13141); cholestasis (Disease Ontology:DOID:13580); peptic esophagitis (Disease Ontology:DOID:13976); brain ischemia (Disease Ontology:DOID:2316); bile duct cancer (Disease Ontology:DOID:4606); gallbladder carcinoma (Disease Ontology:DOID:4948); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); brain disease (Disease Ontology:DOID:936)", "pathway": " (R-RNO-191650); (R-RNO-2028269); (R-RNO-351906)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "16641100;22673903;3528172;9707407", "class_list": "", "function": "TjpP1, Tjp2, and Tjp3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:9707407). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Necessary for lumenogenesis, and particularly efficient epithelial polarization and barrier formation (By similarity). Plays a role in the regulation of cell migration by targeting Cdc42bpb to the leading edge of migrating cells (By similarity). Plays an important role in podosome formation and associated function, thus regulating cell adhesion and matrix remodeling (By similarity). With Tjp2 and Tjp3, participates in the junctional retention and stability of the transcription factor Dbpa, but is not involved in its shuttling to the nucleus (By similarity). May play a role in mediating cell morphology changes during ameloblast differentiation via its role in tight junctions (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 46, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071253 connexin binding;GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0044325 transmembrane transporter binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005912 adherens junction", "go_biological_process": "GO:1903672 positive regulation of sprouting angiogenesis;GO:0150105 protein localization to cell-cell junction;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K2P5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001001.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2Q2-1", "uniprot_id": [ { "id": "A0A0G2K2Q2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2Q2", "type": "external" } ], "mass": 46542.0, "length": 425, "protein_name": "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "gene_name": "Gcat", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gcat", "gene_names_refseq": "", "protein_names_uniprotkb": "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; 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Exophilin-7", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8854214)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0042470 melanosome;GO:0070382 exocytic vesicle;GO:0012505 endomembrane system", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K2R4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2S6-1", "uniprot_id": [ { "id": "A0A0G2K2S6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2S6", "type": "external" } ], "mass": 34821.0, "length": 311, "protein_name": "Olfactory receptor family 10 subfamily G member 9", "gene_name": "Or10g9", "organism": "Rat", "refseq_name": "olfactory receptor Olr1334", "refseq_ac": [ { "id": "NP_001000478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000478", "type": "external" } ], "gene_names_uniprotkb": "Or10g9", "gene_names_refseq": "Olr1334; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030659 cytoplasmic vesicle membrane;GO:0005802 trans-Golgi network;GO:0030123 AP-3 adaptor complex;GO:1904115 axon cytoplasm;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0008089 anterograde axonal transport;GO:0048490 anterograde synaptic vesicle transport;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K302-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K309-1", "uniprot_id": [ { "id": "ORNT1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K309", "type": "external" } ], "mass": 32797.0, "length": 301, "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Slc25a15", "organism": "Rat", "refseq_name": "mitochondrial ornithine transporter 1 isoform X1", "refseq_ac": [ { "id": "XP_006253412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253412", "type": "external" } ], "gene_names_uniprotkb": "Slc25a15", "gene_names_refseq": "Ab1-114; Ornt1; Slc25a15", "protein_names_uniprotkb": "Mitochondrial ornithine transporter 1; Solute carrier family 25 member 15", "protein_names_refseq": "mitochondrial ornithine transporter 1 isoform X1", "tax_id": 10116, "disease": "ornithine translocase deficiency (Disease Ontology:DOID:0050720); amino acid metabolic disorder (Disease Ontology:DOID:9252); citrullinemia (Disease Ontology:DOID:9273)", "pathway": " (rno:306574); (R-RNO-70635)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10417335;9359400", "class_list": "", "function": "Mitochondrial ornithine-citrulline antiporter. Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle (PubMed:10417335, PubMed:9359400). Lysine and arginine are also transported by the antiport mechanism (By similarity). In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane (PubMed:10417335)., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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"0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K313-1", "uniprot_id": [ { "id": "A0A0G2K313_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K313", "type": "external" } ], "mass": 88996.0, "length": 798, "protein_name": "LON peptidase N-terminal domain and RING finger protein 1", "gene_name": "Lonrf1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lonrf1", "gene_names_refseq": "", "protein_names_uniprotkb": "LON peptidase N-terminal domain and RING finger protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-983168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K313-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K314-1", "uniprot_id": [ { "id": "A0A0G2K314_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K314", "type": "external" } ], "mass": 25925.0, "length": 225, "protein_name": "Killer cell lectin-like receptor subfamily H, member 1", "gene_name": "Klrh1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Klrh1", "gene_names_refseq": "", "protein_names_uniprotkb": "Killer cell lectin-like receptor subfamily H, member 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, 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"Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cep170", "gene_names_refseq": "", "protein_names_uniprotkb": "Centrosomal protein 170", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "Plays a role in microtubule organization. Required for centriole subdistal appendage assembly., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0120103 centriolar subdistal appendage", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K315-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K320-1", "uniprot_id": [ { "id": "A0A0G2K320_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K320", "type": "external" } ], "mass": 183373.0, "length": 1700, "protein_name": "Sialoadhesin", "gene_name": "Siglec1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Siglec1", "gene_names_refseq": "", "protein_names_uniprotkb": "Sialoadhesin; Sialic acid-binding Ig-like lectin 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:311426); (R-RNO-198933)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0046790 virion binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005770 late endosome;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0007155 cell adhesion;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0046718 symbiont entry into host cell;GO:0072583 clathrin-dependent endocytosis;GO:0050765 negative regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K320-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K325-1", "uniprot_id": [ { "id": "A0A0G2K325_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K325", "type": "external" } ], "mass": 34324.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "Or4x5", "organism": "Rat", "refseq_name": "olfactory receptor Olr735", "refseq_ac": [ { "id": "NP_001000922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000922", "type": "external" } ], "gene_names_uniprotkb": "Or4x5", "gene_names_refseq": "Olr735; Or4x5", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 735; olfactory receptor Olr735; olfactory receptor gene Olr735", "tax_id": 10116, "disease": "", "pathway": " (rno:405238)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K325-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K332-1", "uniprot_id": [ { "id": "A0A0G2K332_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K332", "type": "external" } ], "mass": 11024.0, "length": 104, "protein_name": "Ig-like domain-containing protein", "gene_name": "AABR07034729.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07034729.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K332-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K344-1", "uniprot_id": [ { "id": "PK3CA_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K344", "type": "external" } ], "mass": 124354.0, "length": 1068, "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "Pik3ca", "organism": "Rat", "refseq_name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "refseq_ac": [ { "id": "NP_596890", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_596890", "type": "external" } ], "gene_names_uniprotkb": "Pik3ca", "gene_names_refseq": "Pik3ca", "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; 2.7.1.137; 2.7.1.153; 2.7.11.1; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; PtdIns-3-kinase subunit alpha; PtdIns-3-kinase subunit p110-alpha; Serine/threonine protein kinase PIK3CA; p110alpha", "protein_names_refseq": "PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; p110alpha; phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphoinositide-3-kinase catalytic alpha polypeptide; ptdIns-3-kinase subunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine protein kinase PIK3CA", "tax_id": 10116, "disease": "estrogen-receptor positive breast cancer (Disease Ontology:DOID:0060075); cerebral cavernous malformation (Disease Ontology:DOID:0060669); colorectal carcinoma (Disease Ontology:DOID:0080199); CLOVES syndrome (Disease Ontology:DOID:0080351); Cowden syndrome 5 (Disease Ontology:DOID:0081001); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); epidermal nevus (Disease Ontology:DOID:0111162); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); rectal benign neoplasm (Disease Ontology:DOID:1984); colon adenocarcinoma (Disease Ontology:DOID:234); ovarian cancer (Disease Ontology:DOID:2394); cutaneous Paget's disease (Disease Ontology:DOID:3450); breast angiosarcoma (Disease Ontology:DOID:4511); esophageal cancer (Disease Ontology:DOID:5041); seborrheic keratosis (Disease Ontology:DOID:6498); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:170911); (R-RNO-109704); (R-RNO-112399); (R-RNO-114604); (R-RNO-1250342); (R-RNO-1257604); (R-RNO-1433557); (R-RNO-1660499); (R-RNO-180292); (R-RNO-186763); (R-RNO-1963642); (R-RNO-198203); (R-RNO-201556); (R-RNO-202424); (R-RNO-2029485); (R-RNO-210993); (R-RNO-2424491); (R-RNO-2730905); (R-RNO-389357); (R-RNO-416476); (R-RNO-4420097); (R-RNO-512988); (R-RNO-5654689); (R-RNO-5654695); (R-RNO-5654710); (R-RNO-5654720); (R-RNO-5673001); (R-RNO-6811558); (R-RNO-8851907); (R-RNO-8853659); (R-RNO-9009391); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9027276); (R-RNO-912526); (R-RNO-912631); (R-RNO-9607240); (R-RNO-9842663); (R-RNO-9927354)", "pathway_count": 39, "publication_count": 3, "publication_id_list": "12220227;20236230;34129205", "class_list": "", "function": "Losartan Protects Podocytes against High Glucose-induced Injury by Inhibiting B7-1 Expression., [RefSeq, PubMed]; PI 3-kinase feedback control of signalling by the insulin receptor and IRS proteins is multifaceted and reciprocal, [RefSeq, PubMed]; Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides. Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins (PubMed:20236230). Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity. Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF. Regulates invadopodia formation through the PDPK1-AKT1 pathway. Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway. Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway. In addition to its lipid kinase activity, it displays a serine-protein kinase activity that results in the autophosphorylation of the p85alpha regulatory subunit as well as phosphorylation of other proteins such as 4EBP1, H-Ras, the IL-3 beta c receptor and possibly others (By similarity). Plays a role in the positive regulation of phagocytosis and pinocytosis (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "1.6.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.-", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.-.-", "type": "external" }, { "id": "2.7.1.151", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.151", "type": "external" }, { "id": "2.7.1.140", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.140", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030295 protein kinase activator activity;GO:0043560 insulin receptor substrate binding;GO:0016303 1-phosphatidylinositol-3-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0014704 intercalated disc", "go_biological_process": "GO:0030835 negative regulation of actin filament depolymerization;GO:0043457 regulation of cellular respiration;GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0086003 cardiac muscle cell contraction;GO:0014870 response to muscle inactivity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K344-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K347-1", "uniprot_id": [ { "id": "A0A0G2K347_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K347", "type": "external" } ], "mass": 76159.0, "length": 651, "protein_name": "Cilia and flagella associated protein 99", "gene_name": "Cfap99", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cfap99", "gene_names_refseq": "", "protein_names_uniprotkb": "Cilia and flagella associated protein 99", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K347-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K351-1", "uniprot_id": [ { "id": "A0A0G2K351_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K351", "type": "external" } ], "mass": 26750.0, "length": 237, "protein_name": "Malectin", "gene_name": "Unc119b", "organism": "Rat", "refseq_name": "protein unc-119 homolog B", "refseq_ac": [ { "id": "NP_001099404", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099404", "type": "external" } ], "gene_names_uniprotkb": "Unc119b", "gene_names_refseq": "RGD1309359; Unc119b", "protein_names_uniprotkb": "Malectin", "protein_names_refseq": "protein unc-119 homolog B; unc-119 homolog B", 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May link the complex to the actin core bundle of microvilli., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity;GO:0003779 actin binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005903 brush border;GO:0015629 actin cytoskeleton;GO:0016020 membrane;GO:0005902 microvillus", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030154 cell differentiation;GO:0030048 actin filament-based movement;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K3A7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K3B6-1", "uniprot_id": [ { "id": "A0A0G2K3B6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K3B6", "type": "external" } ], "mass": 58854.0, "length": 511, "protein_name": "Cyclic nucleotide binding domain containing 1", "gene_name": "Cnbd1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cnbd1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclic nucleotide binding domain containing 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K3B6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K3B7-1", "uniprot_id": [ { "id": "A0A0G2K3B7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "type": "external" } ], "mass": 39336.0, "length": 353, "protein_name": "Protein Wnt", "gene_name": "Wnt7b", "organism": "Rat", "refseq_name": "protein Wnt-7b isoform 2", "refseq_ac": [ { "id": "NP_001399539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001399539", "type": "external" } ], "gene_names_uniprotkb": "Wnt7b", "gene_names_refseq": "Wnt7b", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-7b isoform 2; 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Required for normal fusion of the chorion and the allantois during placenta development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation., [UniProtKB, UniProtKB, UniProtKB]; LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/beta-catenin pathway., [RefSeq, PubMed]; Wnt7b/beta-catenin signaling may play an important role infetal rat alveolar epithelial type II cells (fAEC2) transdifferentiation., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0048018 receptor ligand activity;GO:1902379 chemoattractant activity involved in axon guidance", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0060535 trachea cartilage morphogenesis;GO:0016332 establishment or maintenance of polarity of embryonic epithelium;GO:0032536 regulation of cell projection size;GO:0060482 lobar bronchus development;GO:0072060 outer medullary collecting duct development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K3B7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K3C3-1", "uniprot_id": [ { "id": "A0A0G2K3C3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K3C3", "type": "external" } ], "mass": 64026.0, "length": 595, "protein_name": "Endosomal transmembrane epsin interactor 1", "gene_name": "Entrep1", "organism": "Rat", "refseq_name": "endosomal transmembrane epsin interactor 1", "refseq_ac": [ { "id": "NP_001387747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387747", "type": "external" } ], "gene_names_uniprotkb": "Entrep1; 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May activate transcription by interacting directly with the X-box. May activate transcription from CX3CL1 promoter through the X-box during brain development. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Prdx1l1", "protein_names_uniprotkb": "Peroxiredoxin-1; 1.11.1.24", "protein_names_refseq": "peroxiredoxin 1-like 1; peroxiredoxin-1-like", "tax_id": 10116, "disease": "methylmalonic aciduria and homocystinuria type cblC (Disease Ontology:DOID:0050715)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "34502162", "class_list": "", "function": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" } ], "go_molecular_function": "GO:0008379 thioredoxin peroxidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0045454 cell redox homeostasis;GO:0019430 removal of superoxide radicals;GO:0042744 hydrogen peroxide catabolic process;GO:0045321 leukocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K3Z9-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K402-1", "uniprot_id": [ { "id": "A0A0G2K402_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K402", "type": "external" } ], "mass": 63350.0, "length": 591, "protein_name": "Myelin expression factor 2", "gene_name": "Myef2; Slc24a5", "organism": "Rat", "refseq_name": "myelin expression factor 2", "refseq_ac": [ { "id": "NP_001013223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013223", "type": "external" } ], "gene_names_uniprotkb": "Myef2; Slc24a5; Myef2", "gene_names_refseq": "Myef2", "protein_names_uniprotkb": "Myelin expression factor 2", "protein_names_refseq": "myelin basic protein expression factor 2, repressor; myelin expression factor 2", "tax_id": 10116, "disease": "ocular albinism 1 (Disease Ontology:DOID:0050633); oculocutaneous albinism type VI (Disease Ontology:DOID:0080614)", "pathway": " (rno:679712); (R-RNO-425561)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes., [UniProtKB, UniProtKB, UniProtKB]; Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0015293 symporter activity;GO:0008273 calcium, potassium:sodium antiporter activity;GO:0015085 calcium ion transmembrane transporter activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0016020 membrane;GO:0042470 melanosome;GO:0005802 trans-Golgi network;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0048022 negative regulation of melanin biosynthetic process;GO:0006874 intracellular calcium ion homeostasis;GO:0034220 monoatomic ion transmembrane transport;GO:0070588 calcium ion transmembrane transport;GO:0042438 melanin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K402-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K408-1", "uniprot_id": [ { "id": "A0A0G2K408_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K408", "type": "external" } ], "mass": 34967.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or2ah1", "organism": "Rat", "refseq_name": "olfactory receptor Olr461", "refseq_ac": [ { "id": "NP_001000294", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000294", "type": "external" } ], "gene_names_uniprotkb": "Or2ah1", "gene_names_refseq": "Olr461; Or2ah1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 461; olfactory receptor Olr461; olfactory receptor gene Olr461", "tax_id": 10116, "disease": "", "pathway": " (rno:295730)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. 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180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2", "protein_names_refseq": "collagen alpha-1(XVII) chain isoform 1; collagen alpha-1(XVII) chain; collagen, type XVII, alpha 1; procollagen, type XVII, alpha 1", "tax_id": 10116, "disease": "junctional epidermolysis bullosa non-Herlitz type (Disease Ontology:DOID:0060738); epithelial recurrent erosion dystrophy (Disease Ontology:DOID:0070337); junctional epidermolysis bullosa (Disease Ontology:DOID:3209)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "39265891", "class_list": "", "function": "Junctional Epidermolysis Bullosa in Sprague Dawley Rats Caused by a Frameshift Mutation of Col17a1 Gene., [RefSeq, PubMed]; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0005604 basement membrane;GO:0005581 collagen trimer;GO:0030056 hemidesmosome", "go_biological_process": "GO:0031581 hemidesmosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K449-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K452-1", "uniprot_id": [ { "id": "A0A0G2K452_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K452", "type": "external" } ], "mass": 25463.0, "length": 229, "protein_name": "ascorbate ferrireductase (transmembrane)", "gene_name": "Cyb561d1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cyb561d1", "gene_names_refseq": "", "protein_names_uniprotkb": "ascorbate ferrireductase (transmembrane); 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Or7g34", "organism": "Rat", "refseq_name": "olfactory receptor Olr1149", "refseq_ac": [ { "id": "NP_001000874", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000874", "type": "external" } ], "gene_names_uniprotkb": "Or7g34b; Or7g34; Or7g34", "gene_names_refseq": "Olr1149; Or7g34", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1149; olfactory receptor Olr1149; olfactory receptor gene Olr1149", "tax_id": 10116, "disease": "", "pathway": " (rno:405172)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K469-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K470-1", "uniprot_id": [ { "id": "A0A0G2K470_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K470", "type": "external" } ], "mass": 128839.0, "length": 1178, "protein_name": "Integrin alpha-2", "gene_name": "Itga2", "organism": "Rat", "refseq_name": "integrin alpha-2 precursor", "refseq_ac": [ { "id": "NP_001414220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414220", "type": "external" } ], "gene_names_uniprotkb": "Itga2", "gene_names_refseq": "CD49B; GPIa; HPA-5; Itga2", "protein_names_uniprotkb": "Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; VLA-2 subunit alpha", "protein_names_refseq": "integrin alpha 2; integrin alpha-2 precursor; platelet glycoprotein Ia", "tax_id": 10116, "disease": "von Willebrand's disease 1 (Disease Ontology:DOID:0060573); von Willebrand's disease 2 (Disease Ontology:DOID:0060574); thrombosis (Disease Ontology:DOID:0060903); sensorineural hearing loss (Disease Ontology:DOID:10003); iron deficiency anemia (Disease Ontology:DOID:11758); Behcet's disease (Disease Ontology:DOID:13241); thrombocytopenia (Disease Ontology:DOID:1588); retinal vein occlusion (Disease Ontology:DOID:1727); Glanzmann's thrombasthenia (Disease Ontology:DOID:2219); arteriosclerosis (Disease Ontology:DOID:2349); placental insufficiency (Disease Ontology:DOID:3891); myocardial infarction (Disease Ontology:DOID:5844); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (R-RNO-216083); (R-RNO-3000170); (R-RNO-3000178); (R-RNO-8874081)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "27169768;27827993;29023021;31964805", "class_list": "", "function": "Bone marrow-mesenchymal stem cell treatment was able to accelerate the healing process of burns by increasing the thickness of the collagen and the percentage of integrin alpha2beta1, thus accelerating the cell migration involved during wound healing., [RefSeq, PubMed]; Ca(2+) waves coordinate purinergic receptor-evoked integrin activation and polarization. Publication Status: Online-Only, [RefSeq, PubMed]; Hydrostatic mechanical force enhances the viability and decreases the apoptosis of condylar chondrocytes through integrin-FAK-ERK/PI3K pathway. Publication Status: Online-Only, [RefSeq, PubMed]; The interaction of alpha2beta1 integrin to collagen I in the cellular microenvironment can regulate expression of LOX., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 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"0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K490-1", "uniprot_id": [ { "id": "A0A0G2K490_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K490", "type": "external" } ], "mass": 154971.0, "length": 1360, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Tnik", "organism": "Rat", "refseq_name": "TRAF2 and NCK-interacting protein kinase isoform 2", "refseq_ac": [ { "id": "XP_017446219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017446219", "type": "external" } ], "gene_names_uniprotkb": "Tnik", "gene_names_refseq": "RGD1561817; Tnik", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "TRAF2 and NCK-interacting protein kinase isoform 2; TRAF2 and NCK-interacting protein kinase", "tax_id": 10116, "disease": "autosomal recessive intellectual developmental disorder 54 (Disease Ontology:DOID:0081216); epilepsy (Disease 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"https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0030033 microvillus assembly;GO:0035556 intracellular signal transduction;GO:0046330 positive regulation of JNK cascade;GO:0048814 regulation of dendrite morphogenesis;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K490-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4A0-1", "uniprot_id": [ { "id": "A0A0G2K4A0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4A0", "type": "external" } ], "mass": 69989.0, "length": 648, "protein_name": "Rab11 family-interacting protein 5", "gene_name": "Rab11fip5", "organism": "Rat", "refseq_name": "rab11 family-interacting protein 5", "refseq_ac": [ { "id": "NP_001386477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386477", "type": "external" } ], "gene_names_uniprotkb": "Rab11fip5", "gene_names_refseq": "Rab11fip5", "protein_names_uniprotkb": "Rab11 family-interacting protein 5; Rab11-interacting protein Rip11", "protein_names_refseq": "RAB11 family interacting protein 5 (class I); rab11 family-interacting protein 5", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005741 mitochondrial outer membrane;GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0070164 negative regulation of adiponectin secretion;GO:0098884 postsynaptic neurotransmitter receptor internalization;GO:0045055 regulated exocytosis;GO:0071346 cellular response to type II interferon;GO:0071468 cellular response to acidic pH", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K4A0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4A8-1", "uniprot_id": [ { "id": "A0A0G2K4A8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4A8", "type": "external" } ], "mass": 115364.0, "length": 1042, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Lats2", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase LATS2", "refseq_ac": [ { "id": "NP_001100737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100737", "type": "external" } ], "gene_names_uniprotkb": "Lats2", "gene_names_refseq": "Lats2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "large tumor suppressor 2; large tumor suppressor, homolog 2; serine/threonine-protein kinase LATS2", "tax_id": 10116, "disease": "benign neoplasm (Disease Ontology:DOID:0060072); neurodegenerative disease (Disease Ontology:DOID:1289); cancer (Disease Ontology:DOID:162); kidney cancer (Disease Ontology:DOID:263); carcinoma (Disease Ontology:DOID:305); peripheral nerve sheath neoplasm (Disease Ontology:DOID:3193); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:305922); (R-RNO-2028269)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "31829064;32054526;32375631", "class_list": "", "function": "Exosomal miR-135a derived from human amnion mesenchymal stem cells promotes cutaneous wound healing in rats and fibroblast migration by directly inhibiting LATS2 expression. Publication Status: Online-Only, [RefSeq, PubMed]; The overexpression of LATS2 induces mitochondrial stress by repressing protective mitophagy in a manner dependent on Prx3-Mfn2 pathways, thus reducing the survival of H9C2 cells., [RefSeq, PubMed]; Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in developing neurons by targeting LATS2. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, 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"external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0034451 centriolar satellite", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0051301 cell division;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K4A8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4B0-1", "uniprot_id": [ { "id": "A0A0G2K4B0_RAT", 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"2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0060090 molecular adaptor activity;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0090734 site of DNA damage;GO:0016604 nuclear body", "go_biological_process": "GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0034644 cellular response to UV", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4L7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": 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"binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016790 thiolester hydrolase activity;GO:0047617 fatty acyl-CoA hydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006637 acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4M8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4N0-1", "uniprot_id": [ { "id": "A0A0G2K4N0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4N0", "type": "external" } ], "mass": 12702.0, "length": 117, "protein_name": "Uncharacterized protein", "gene_name": "AABR07016640.3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07016640.3", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": 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"reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4N0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4Q5-1", "uniprot_id": [ { "id": "A0A0G2K4Q5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4Q5", "type": "external" } ], "mass": 24121.0, "length": 210, "protein_name": "Glutathione S-transferase", "gene_name": "Gstp3", "organism": "Rat", "refseq_name": "Glutathione S-transferase P-like isoform 1", "refseq_ac": [ { "id": "NP_001385709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385709", "type": "external" } ], "gene_names_uniprotkb": "Gstp3; RGD1307603", "gene_names_refseq": "Gstp3; RGD1307603", "protein_names_uniprotkb": "Glutathione S-transferase; 2.5.1.18; GST class-pi", "protein_names_refseq": "Glutathione S-transferase P-like isoform 1; Glutathione S-transferase P-like", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:293656)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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"id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "7.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.4.2.-", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4Q5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4Q7-1", "uniprot_id": [ { "id": "A0A0G2K4Q7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4Q7", "type": "external" } ], "mass": 239375.0, "length": 2176, "protein_name": "Polycystin-1-like protein 3", "gene_name": "Pkd1l3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pkd1l3", "gene_names_refseq": "", "protein_names_uniprotkb": "Polycystin-1-like protein 3; PC1-like 3 protein; Polycystic kidney disease protein 1-like 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pore-forming subunit of a heterotetrameric, non-selective cation channel that is permeable to Ca(2+). Also shows permeability towards NA(1+), K(+) and Mg(2+). Heterotetrameric complex channel is activated by external low pH and Ca(2+), but opens only when the extracellular pH rises again and after the removal of acid stimulus. May act as a sour taste receptor in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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monoatomic cation transport;GO:0070588 calcium ion transmembrane transport;GO:0050915 sensory perception of sour taste;GO:0071468 cellular response to acidic pH", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4Q7-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4R1-1", "uniprot_id": [ { "id": "A0A0G2K4R1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4R1", "type": "external" } ], "mass": 84766.0, "length": 784, "protein_name": "Protein phosphatase 1 regulatory subunit", "gene_name": "Ppp1r12c", "organism": "Rat", "refseq_name": "protein phosphatase 1 regulatory subunit 12C", "refseq_ac": [ { "id": "NP_001178875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178875", "type": "external" } ], "gene_names_uniprotkb": "Ppp1r12c", "gene_names_refseq": "Ppp1r12c", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit", 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"0000000.0000101.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4R2-1", "uniprot_id": [ { "id": "A0A0G2K4R2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4R2", "type": "external" } ], "mass": 54885.0, "length": 479, "protein_name": "glucuronosyltransferase", "gene_name": "Ugt3a1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ugt3a1; Ugt3a2", "gene_names_refseq": "", "protein_names_uniprotkb": "glucuronosyltransferase; 2.4.1.17", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-156588); (R-RNO-9749641)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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"go_molecular_function": "GO:0008194 UDP-glycosyltransferase activity;GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0043541 UDP-N-acetylglucosamine transferase complex", "go_biological_process": "GO:0071412 cellular response to genistein", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4R2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4R3-1", "uniprot_id": [ { "id": "A0A0G2K4R3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4R3", "type": "external" } ], "mass": 55112.0, "length": 468, "protein_name": "Zinc finger protein 933", "gene_name": "Zfp933", "organism": "Rat", "refseq_name": "similar to Zinc finger protein 180 (HHZ168)", "refseq_ac": [ { "id": "NP_001396210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001396210", "type": "external" } ], "gene_names_uniprotkb": "Zfp933; LOC691280", "gene_names_refseq": "Zfp933", "protein_names_uniprotkb": "Zinc finger protein 933", "protein_names_refseq": "similar to Zinc finger protein 180 (HHZ168); zinc finger protein 431", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4R3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4S0-1", "uniprot_id": [ { "id": "A0A0G2K4S0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4S0", "type": "external" } ], "mass": 62511.0, "length": 558, "protein_name": "Schlafen family member 4 like 1", "gene_name": "Slfn4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slfn4; Slfn4l1", "gene_names_refseq": "", "protein_names_uniprotkb": "Schlafen family member 4 like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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"GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0048286 lung alveolus development;GO:0097190 apoptotic signaling pathway;GO:0009617 response to bacterium;GO:0016075 rRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4S0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4S4-1", "uniprot_id": [ { "id": "A0A0G2K4S4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4S4", "type": "external" } ], "mass": 75697.0, "length": 687, "protein_name": "ATP-dependent RNA helicase", "gene_name": "Ddx51", "organism": "Rat", "refseq_name": "ATP-dependent RNA helicase DDX51", "refseq_ac": [ { "id": "XP_006249623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249623", "type": "external" } ], "gene_names_uniprotkb": "Ddx51", "gene_names_refseq": "Ddx51", "protein_names_uniprotkb": "ATP-dependent RNA helicase; 3.6.4.13", "protein_names_refseq": "ATP-dependent RNA helicase DDX51; DEAD (Asp-Glu-Ala-Asp) box polypeptide 51", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits., [UniProtKB, UniProtKB, UniProtKB]; RNA helicase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4S4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4S7-1", "uniprot_id": [ { "id": "A0A0G2K4S7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4S7", "type": "external" } ], "mass": 90346.0, "length": 812, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp45", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 45", "refseq_ac": [ { "id": "NP_001382490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382490", "type": "external" } ], "gene_names_uniprotkb": "Usp45", "gene_names_refseq": "Usp45", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 45; ubiquitin specific petidase 45; ubiquitin specific protease 45", "tax_id": 10116, "disease": "Leber congenital amaurosis 19 (Disease Ontology:DOID:0081169)", "pathway": " (R-RNO-5696395)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. 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Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR)., [UniProtKB, UniProtKB]; 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. 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0.1, "record_id": "A0A0G2K574-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K583-1", "uniprot_id": [ { "id": "A0A0G2K583_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K583", "type": "external" } ], "mass": 31089.0, "length": 283, "protein_name": "S-methyl-5'-thioadenosine phosphorylase", "gene_name": "Mtap", "organism": "Rat", "refseq_name": "S-methyl-5'-thioadenosine phosphorylase", "refseq_ac": [ { "id": "NP_001380978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001380978", "type": "external" } ], "gene_names_uniprotkb": "Mtap; MTAP; Mtap_predicted", "gene_names_refseq": "Cc1-6; Mtap", "protein_names_uniprotkb": "S-methyl-5'-thioadenosine phosphorylase; 2.4.2.28; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAPase; MTAP", "protein_names_refseq": "5'-methylthioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase", "tax_id": 10116, "disease": "biliary tract benign neoplasm (Disease Ontology:DOID:0050625); diaphyseal medullary stenosis with malignant fibrous histiocytoma (Disease Ontology:DOID:0080664); pancreatic cancer (Disease Ontology:DOID:1793); common bile duct neoplasm (Disease Ontology:DOID:4608)", "pathway": " (R-RNO-1237112)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27748820", "class_list": "", "function": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates., [UniProtKB, HAMAP, UniProtKB, UniProtKB]; These protein profiles, and their interacting protein network, may facilitate the elucidation of the molecular mechanisms underlying the antiinflammatory effects of CC16., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.28", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.28", "type": "external" }, { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" } ], "go_molecular_function": "GO:0017061 S-methyl-5-thioadenosine phosphorylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006166 purine ribonucleoside salvage;GO:0032259 methylation;GO:0019509 L-methionine salvage from methylthioadenosine;GO:0033574 response to testosterone", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K583-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K598-1", "uniprot_id": [ { "id": "A0A0G2K598_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K598", "type": "external" } ], "mass": 304690.0, "length": 2874, "protein_name": "Transforming, acidic coiled-coil containing protein 2", "gene_name": "Tacc2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tacc2", "gene_names_refseq": "", "protein_names_uniprotkb": "Transforming, acidic coiled-coil containing protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0021987 cerebral cortex development;GO:0032886 regulation of microtubule-based process;GO:0000226 microtubule cytoskeleton organization;GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K598-1", "record_type": "protein", "filter_code": "0000000.0000100.001000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5B0-1", "uniprot_id": [ { "id": "A0A0G2K5B0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5B0", "type": "external" } ], "mass": 63410.0, "length": 562, "protein_name": "TBC1 domain family member 24", "gene_name": "Tbc1d24", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tbc1d24", "gene_names_refseq": "", "protein_names_uniprotkb": "TBC1 domain family member 24", "protein_names_refseq": "", "tax_id": 10116, "disease": "nonsyndromic deafness (Disease Ontology:DOID:0050563); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); developmental and epileptic encephalopathy 16 (Disease Ontology:DOID:0080449); autosomal recessive nonsyndromic deafness 86 (Disease Ontology:DOID:0110532); autosomal dominant nonsyndromic deafness 65 (Disease Ontology:DOID:0110586); DOORS syndrome (Disease Ontology:DOID:0111627); Rolandic epilepsy-paroxysmal exercise-induced dystonia-writer's cramp syndrome (Disease Ontology:DOID:0111645); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (rno:287110); (R-RNO-8854214)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. Involved in the regulation of synaptic vesicle trafficking., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0042995 cell projection;GO:0098793 presynapse", "go_biological_process": "GO:0016358 dendrite development;GO:0031175 neuron projection development;GO:2000463 positive regulation of excitatory postsynaptic potential;GO:0034599 cellular response to oxidative stress;GO:0050775 positive regulation of dendrite morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5B0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5B5-1", "uniprot_id": [ { "id": "A0A0G2K5B5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5B5", "type": "external" } ], "mass": 92861.0, "length": 810, "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "ENSRNOG00000068544", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000068544; Vmn2r65", "gene_names_refseq": "", "protein_names_uniprotkb": "G-protein coupled receptors family 3 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5B5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5D7-1", "uniprot_id": [ { "id": "A0A0G2K5D7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5D7", "type": "external" } ], "mass": 117359.0, "length": 1058, "protein_name": "Sperm antigen with calponin homology and coiled-coil domains 1", "gene_name": "Specc1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Specc1; Cytsb; RGD1309718", "gene_names_refseq": "", "protein_names_uniprotkb": "Sperm antigen with calponin homology and coiled-coil domains 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:303208)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045177 apical part of cell;GO:0005815 microtubule organizing center;GO:0031941 filamentous actin", "go_biological_process": "GO:0008306 associative learning;GO:0030036 actin cytoskeleton organization;GO:0001824 blastocyst development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5D7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5E4-1", "uniprot_id": [ { "id": "A0A0G2K5E4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5E4", "type": "external" } ], "mass": 52403.0, "length": 480, "protein_name": "DnaJ homolog subfamily A member 3, mitochondrial", "gene_name": "Dnaja3", "organism": "Rat", "refseq_name": "dnaJ homolog subfamily A member 3, mitochondrial isoform 1", "refseq_ac": [ { "id": "NP_001033684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033684", "type": "external" } ], "gene_names_uniprotkb": "Dnaja3", "gene_names_refseq": "Dnaja3; Tid-1", "protein_names_uniprotkb": "DnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Tumorous imaginal discs protein Tid56 homolog", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily A, member 3; dnaJ homolog subfamily A member 3, mitochondrial isoform 1; dnaJ homolog subfamily A member 3, mitochondrial", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "22016808;31081962;38843836", "class_list": "", "function": "Changes in cellular TID1 are a factor in the pathogenesis of Parkinson's disease, [RefSeq, PubMed]; Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway., [UniProtKB, UniProtKB, UniProtKB]; Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005133 type II interferon receptor binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007528 neuromuscular junction development;GO:0008285 negative regulation of cell population proliferation;GO:0006915 apoptotic process;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K5E4-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5F6-1", "uniprot_id": [ { "id": "A0A0G2K5F6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5F6", "type": "external" } ], "mass": 37082.0, "length": 333, "protein_name": "SLAM family member 7", "gene_name": "Slamf7", "organism": "Rat", "refseq_name": "SLAM family member 7 precursor", "refseq_ac": [ { "id": "NP_001399756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001399756", "type": "external" } ], "gene_names_uniprotkb": "Slamf7", "gene_names_refseq": "RGD1560190; Slamf7", "protein_names_uniprotkb": "SLAM family member 7", "protein_names_refseq": "SLAM family member 7 precursor", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-198933)", "pathway_count": 1, 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0042110 T cell activation;GO:0032814 regulation of natural killer cell activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5F6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5F7-1", "uniprot_id": [ { "id": "A0A0G2K5F7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5F7", "type": "external" } ], "mass": 17520.0, "length": 154, "protein_name": "Zinc finger, HIT-type containing 1", "gene_name": "Znhit1", "organism": "Rat", "refseq_name": "zinc finger HIT domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_006249153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249153", "type": "external" } ], "gene_names_uniprotkb": "Znhit1", "gene_names_refseq": "Znhit1", "protein_names_uniprotkb": "Zinc finger, HIT-type containing 1", "protein_names_refseq": "zinc finger HIT domain-containing protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0070317 negative regulation of G0 to G1 transition;GO:0045815 transcription initiation-coupled chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5F7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5G5-1", "uniprot_id": [ { "id": "A0A0G2K5G5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5G5", "type": "external" } ], "mass": 32214.0, "length": 287, "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "Alkbh2", "organism": "Rat", "refseq_name": "DNA oxidative demethylase ALKBH2 isoform X1", "refseq_ac": [ { "id": "XP_006249560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249560", "type": "external" } ], "gene_names_uniprotkb": "Alkbh2", "gene_names_refseq": "Alkbh2; RGD1306377", "protein_names_uniprotkb": "DNA oxidative demethylase ALKBH2; 1.14.11.33; Alkylated DNA repair protein alkB homolog 2; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2", "protein_names_refseq": "DNA oxidative demethylase ALKBH2 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"https://www.rhea-db.org/rhea/?query=ec:1.14.11.54", "type": "external" } ], "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0016706 2-oxoglutarate-dependent dioxygenase activity;GO:0051747 cytosine C-5 DNA demethylase activity;GO:0000182 rDNA binding;GO:0035516 broad specificity oxidative DNA demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006307 DNA alkylation repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5G5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5L1-1", "uniprot_id": [ { "id": "A0A0G2K5L1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L1", "type": "external" } ], "mass": 507345.0, "length": 4601, "protein_name": "FAT atypical cadherin 1", "gene_name": "Fat1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fat1", "gene_names_refseq": "", "protein_names_uniprotkb": "FAT atypical cadherin 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727); nephrotic syndrome (Disease Ontology:DOID:1184); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung small cell carcinoma (Disease Ontology:DOID:5409); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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membrane;GO:0005911 cell-cell junction;GO:0030027 lamellipodium", "go_biological_process": "GO:1904385 cellular response to angiotensin;GO:0007015 actin filament organization;GO:0001764 neuron migration;GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K5L1-1", "record_type": "protein", "filter_code": "0000000.0000110.000100.0000000000001000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5L2-1", "uniprot_id": [ { "id": "GHC1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L2", "type": "external" } ], "mass": 34662.0, "length": 323, "protein_name": "Mitochondrial glutamate carrier 1", "gene_name": "Slc25a22", "organism": "Rat", "refseq_name": "mitochondrial glutamate carrier 1 isoform 3", "refseq_ac": [ { "id": "NP_001014049", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014049", "type": "external" } ], "gene_names_uniprotkb": "Slc25a22; Gc1", "gene_names_refseq": "GC-1; GC1; RGD1307826; Slc25a22", "protein_names_uniprotkb": "Mitochondrial glutamate carrier 1; GC-1; Glutamate/H(+) symporter 1; Solute carrier family 25 member 22", "protein_names_refseq": "glutamate/H(+) symporter 1; mitochondrial glutamate carrier 1 isoform 3; mitochondrial glutamate carrier 1-like; mitochondrial glutamate carrier 1; solute carrier family 25 (mitochondrial carrier, glutamate), member 22", "tax_id": 10116, "disease": "developmental and epileptic encephalopathy 3 (Disease Ontology:DOID:0080440)", "pathway": " (rno:309111); (R-RNO-442660); (R-RNO-9856872)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "19584051;38843836", "class_list": "", "function": "Insulin-secreting cells depend on GC1 for maximal glucose response., [RefSeq, PubMed]; Mitochondrial glutamate/H(+) symporter (By similarity). Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (Probable). Plays a role in the control of glucose-stimulated insulin secretion (PubMed:19584051)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZRF5;Q5FVG4", "ec_number_list": [], "go_molecular_function": "GO:0005280 amino acid:proton symporter activity;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0050796 regulation of insulin secretion;GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K5L2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5L3-1", "uniprot_id": [ { "id": "A0A0G2K5L3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3", "type": "external" } ], "mass": 65185.0, "length": 566, "protein_name": "Serine/threonine-protein kinase RIO1", "gene_name": "Riok1", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase RIO1", "refseq_ac": [ { "id": "NP_001093981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093981", "type": "external" } ], "gene_names_uniprotkb": "Riok1", "gene_names_refseq": "Riok1", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIO1; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase RIO1", "tax_id": 10116, "disease": "colon cancer (Disease Ontology:DOID:219)", "pathway": " (rno:291061); (R-RNO-6791226)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity;GO:0140002 histone H3K4me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000228 nuclear chromosome;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0043923 positive regulation by host of viral transcription;GO:0034728 nucleosome organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5T4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5U3-1", "uniprot_id": [ { "id": "A0A0G2K5U3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5U3", "type": "external" } ], "mass": 36926.0, "length": 334, "protein_name": "Endonuclease V", "gene_name": "Endov", "organism": "Rat", "refseq_name": "endonuclease V", "refseq_ac": [ { "id": "NP_001388992", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388992", "type": "external" } ], "gene_names_uniprotkb": "Endov; LOC498029", "gene_names_refseq": "Endov", "protein_names_uniprotkb": "Endonuclease V", "protein_names_refseq": "endonuclease V", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Active against both single-stranded and double-stranded RNAs. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003677 DNA binding;GO:0003727 single-stranded RNA binding;GO:0016888 DNA endonuclease activity, producing 5'-phosphomonoesters;GO:0016891 RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5U3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5V0-1", "uniprot_id": [ { "id": "A0A0G2K5V0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5V0", "type": "external" } ], "mass": 21502.0, "length": 185, "protein_name": "CKLF-like MARVEL transmembrane domain containing 2B", "gene_name": "Cmtm2b", "organism": "Rat", "refseq_name": "CKLF-like MARVEL transmembrane domain-containing protein 2B-like", "refseq_ac": [ { "id": "NP_001406615", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406615", "type": "external" } ], "gene_names_uniprotkb": "Cmtm2b; LOC102554842", "gene_names_refseq": "Cmtm2b", "protein_names_uniprotkb": "CKLF-like MARVEL transmembrane domain containing 2B", "protein_names_refseq": "CKLF-like MARVEL transmembrane domain-containing protein 2B-like; CKLF-like MARVEL transmembrane domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5V0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5V2-1", "uniprot_id": [ { "id": "A0A0G2K5V2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5V2", "type": "external" } ], "mass": 27282.0, "length": 238, "protein_name": "Y-linked testis-specific protein 1-like", "gene_name": "LOC134486221", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC134486221; LOC134478817; LOC134480940; LOC134481117", "gene_names_refseq": "", "protein_names_uniprotkb": "Y-linked testis-specific protein 1-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5V2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5V4-1", "uniprot_id": [ { "id": "A0A0G2K5V4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5V4", "type": "external" } ], "mass": 429286.0, "length": 3813, "protein_name": "Lysosomal-trafficking regulator", "gene_name": "AABR07028902.1; Lyst", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07028902.1; Lyst; AABR07028902.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysosomal-trafficking regulator", "protein_names_refseq": "", "tax_id": 10116, "disease": "exfoliation syndrome (Disease Ontology:DOID:13641); platelet storage pool deficiency (Disease Ontology:DOID:2223); Chediak-Higashi syndrome (Disease Ontology:DOID:2935)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Adapter protein that regulates and/or fission of intracellular vesicles such as lysosomes. Might regulate trafficking of effectors involved in exocytosis. In cytotoxic T-cells and natural killer (NK) cells, has role in the regulation of size, number and exocytosis of lytic granules. In macrophages and dendritic cells, regulates phagosome maturation by controlling the conversion of early phagosomal compartments into late phagosomes. In macrophages and dendritic cells, specifically involved in TLR3- and TLR4-induced production of pro-inflammatory cytokines by regulating the endosomal TLR3- TICAM1/TRIF and TLR4- TICAM1/TRIF signaling pathways., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0051607 defense response to virus;GO:0002446 neutrophil mediated immunity;GO:0006909 phagocytosis;GO:0007596 blood coagulation;GO:0055091 phospholipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5V4-1", "record_type": "protein", "filter_code": "0000000.0000110.001000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5W1-1", "uniprot_id": [ { "id": "A0A0G2K5W1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5W1", "type": "external" } ], "mass": 146763.0, "length": 1405, "protein_name": "NCK-associated protein 5-like", "gene_name": "Nckap5l", "organism": "Rat", "refseq_name": "nck-associated protein 5-like", "refseq_ac": [ { "id": "NP_001258298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258298", "type": "external" } ], "gene_names_uniprotkb": "Nckap5l", "gene_names_refseq": "Nckap5l; RGD1561571", "protein_names_uniprotkb": "NCK-associated protein 5-like", "protein_names_refseq": "nck-associated protein 5-like", "tax_id": 10116, "disease": "", "pathway": " (rno:315297)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0007019 microtubule depolymerization;GO:0001578 microtubule bundle formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5W1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5W4-1", "uniprot_id": [ { "id": "A0A0G2K5W4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5W4", "type": "external" } ], "mass": 72460.0, "length": 640, "protein_name": "CREB3 regulatory factor", "gene_name": "Crebrf", "organism": "Rat", "refseq_name": "CREB3 regulatory factor", "refseq_ac": [ { "id": "NP_001264086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264086", "type": "external" } ], "gene_names_uniprotkb": "Crebrf", "gene_names_refseq": "Crebrf; RGD1310862", "protein_names_uniprotkb": "CREB3 regulatory factor", "protein_names_refseq": "CREB3 regulatory factor", "tax_id": 10116, "disease": "", "pathway": " (rno:303016); (R-RNO-8874211)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0016604 nuclear body;GO:0005634 nucleus", "go_biological_process": "GO:1902213 positive regulation of prolactin signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006986 response to unfolded protein;GO:0042711 maternal behavior;GO:2000323 negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5W4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5X2-1", "uniprot_id": [ { "id": "A0A0G2K5X2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5X2", "type": "external" } ], "mass": 123563.0, "length": 1105, "protein_name": "General transcription factor II-I repeat domain-containing protein 1", "gene_name": "Gtf2ird1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gtf2ird1", "gene_names_refseq": "", "protein_names_uniprotkb": "General transcription factor II-I repeat domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Williams-Beuren syndrome (Disease Ontology:DOID:1928)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0014886 transition between slow and fast fiber", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5X2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5X7-1", "uniprot_id": [ { "id": "A0A0G2K5X7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5X7", "type": "external" } ], "mass": 15087.0, "length": 136, "protein_name": "Histone H3", "gene_name": "H3f3al3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "H3f3al3; RGD1564447", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone H3", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:367254)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5X7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5Y3-1", "uniprot_id": [ { "id": "A0A0G2K5Y3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5Y3", "type": "external" } ], "mass": 48949.0, "length": 431, "protein_name": "Testis expressed 9", "gene_name": "Tex9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tex9", "gene_names_refseq": "", "protein_names_uniprotkb": "Testis expressed 9", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0034451 centriolar satellite", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5Y3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5Z6-1", "uniprot_id": [ { "id": "A0A0G2K5Z6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5Z6", "type": "external" } ], "mass": 58828.0, "length": 543, "protein_name": "BEN domain containing 4", "gene_name": "Bend4", "organism": "Rat", "refseq_name": "BEN domain-containing protein 4 isoform X1", "refseq_ac": [ { "id": "XP_006251044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006251044", "type": "external" } ], "gene_names_uniprotkb": "Bend4", "gene_names_refseq": "Bend4", "protein_names_uniprotkb": "BEN domain containing 4", "protein_names_refseq": "BEN domain-containing protein 4 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5Z6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K602-1", "uniprot_id": [ { "id": "A0A0G2K602_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K602", "type": "external" } ], "mass": 77504.0, "length": 694, "protein_name": "Nitric oxide associated 1", "gene_name": "Noa1", "organism": "Rat", "refseq_name": "nitric oxide-associated protein 1 isoform 1", "refseq_ac": [ { "id": "NP_001388376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388376", "type": "external" } ], "gene_names_uniprotkb": "Noa1; RGD1359460", "gene_names_refseq": "Noa1; RGD1359460", "protein_names_uniprotkb": "Nitric oxide associated 1", "protein_names_refseq": "MMR_HSR1 domain containing protein RGD1359460; nitric oxide-associated protein 1 isoform 1; nitric oxide-associated protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:289562)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0099617 matrix side of mitochondrial inner membrane", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0061668 mitochondrial ribosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K602-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K603-1", "uniprot_id": [ { "id": "A0A0G2K603_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K603", "type": "external" } ], "mass": 56440.0, "length": 490, "protein_name": "Angiopoietin-like 1", "gene_name": "Angptl1", "organism": "Rat", "refseq_name": "angiopoietin-related protein 1 precursor", "refseq_ac": [ { "id": "NP_001389285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001389285", "type": "external" } ], "gene_names_uniprotkb": "Angptl1", "gene_names_refseq": "Angptl1", "protein_names_uniprotkb": "Angiopoietin-like 1", "protein_names_refseq": "angiopoietin-related protein 1 precursor; angiopoietin-related protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "19786610", "class_list": "", "function": "No gross E2 effect on the ependymal pattern of Angpt1 or cerebral Angpt1 protein content is observed., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007596 blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K603-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K604-1", "uniprot_id": [ { "id": "A0A0G2K604_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K604", "type": "external" } ], "mass": 30778.0, "length": 268, "protein_name": "RING-type domain-containing protein", "gene_name": "AABR07045341.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07045341.1", "gene_names_refseq": "", "protein_names_uniprotkb": "RING-type domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K604-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K606-1", "uniprot_id": [ { "id": "A0A0G2K606_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K606", "type": "external" } ], "mass": 7934.0, "length": 71, "protein_name": "General transcription and DNA repair factor IIH subunit TFB5", "gene_name": "LOC120103497", "organism": "Rat", "refseq_name": "general transcription factor IIH subunit 5-like", "refseq_ac": [ { "id": "XP_038969029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038969029", "type": "external" } ], "gene_names_uniprotkb": "LOC120103497", "gene_names_refseq": "LOC120103497", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH subunit TFB5", "protein_names_refseq": "general transcription factor IIH subunit 5-like", "tax_id": 10116, "disease": "trichothiodystrophy (Disease Ontology:DOID:0111866); photosensitive trichothiodystrophy 3 (Disease Ontology:DOID:0111871)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell., [UniProtKB, UniProtKB]; In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005675 transcription factor TFIIH holo complex;GO:0000439 transcription factor TFIIH core complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006294 nucleotide-excision repair, preincision complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K606-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K610-1", "uniprot_id": [ { "id": "A0A0G2K610_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K610", "type": "external" } ], "mass": 44225.0, "length": 402, "protein_name": "KLF transcription factor 12", "gene_name": "Klf12", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Klf12", "gene_names_refseq": "", "protein_names_uniprotkb": "KLF transcription factor 12", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:1901653 cellular response to peptide", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K610-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K612-1", "uniprot_id": [ { "id": "A0A0G2K612_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K612", "type": "external" } ], "mass": 86104.0, "length": 757, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Smurf1", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase SMURF1 isoform X4", "refseq_ac": [ { "id": "XP_006248944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248944", "type": "external" } ], "gene_names_uniprotkb": "Smurf1", "gene_names_refseq": "RGD1309707; Smurf1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase SMURF1 isoform X4", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-201451); (R-RNO-2173791); (R-RNO-4608870); (R-RNO-5632684); (R-RNO-8941858); (R-RNO-983168)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0005160 transforming growth factor beta receptor binding;GO:0046332 SMAD binding;GO:0004842 ubiquitin-protein transferase activity;GO:0070412 R-SMAD binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0030424 axon;GO:0043025 neuronal cell body", "go_biological_process": "GO:1903861 positive regulation of dendrite extension;GO:0030154 cell differentiation;GO:0051607 defense response to virus;GO:0072659 protein localization to plasma membrane;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K612-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K615-1", "uniprot_id": [ { "id": "A0A0G2K615_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K615", "type": "external" } ], "mass": 25936.0, "length": 237, "protein_name": "Opa interacting protein 5", "gene_name": "Oip5", "organism": "Rat", "refseq_name": "protein Mis18-beta", "refseq_ac": [ { "id": "NP_001333352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333352", "type": "external" } ], "gene_names_uniprotkb": "Oip5", "gene_names_refseq": "Oip5; RGD1564263", "protein_names_uniprotkb": "Opa interacting protein 5", "protein_names_refseq": "protein Mis18-beta", "tax_id": 10116, "disease": "", "pathway": " (rno:499873); (R-RNO-606279)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "34229010", "class_list": "", "function": "Raf1 interacts with OIP5 to participate in oxaliplatin-induced neuropathic pain., [RefSeq, PubMed]; Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin;GO:0015030 Cajal body", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0034080 CENP-A containing chromatin assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K615-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K618-1", "uniprot_id": [ { "id": "A0A0G2K618_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K618", "type": "external" } ], "mass": 87980.0, "length": 756, "protein_name": "LARGE xylosyl- and glucuronyltransferase 1", "gene_name": "Large1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Large1", "gene_names_refseq": "", "protein_names_uniprotkb": "LARGE xylosyl- and glucuronyltransferase 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); muscular dystrophy-dystroglycanopathy type B6 (Disease Ontology:DOID:0110637); congenital muscular dystrophy-dystroglycanopathy type A6 (Disease Ontology:DOID:0111242); facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727)", "pathway": " (R-RNO-9939291)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.4.-.-", "type": "external" } ], "go_molecular_function": "GO:0042285 xylosyltransferase activity;GO:0030145 manganese ion binding;GO:0016757 glycosyltransferase activity;GO:0015020 glucuronosyltransferase activity;GO:0016758 hexosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0032991 protein-containing complex", "go_biological_process": "GO:0043403 skeletal muscle tissue regeneration;GO:0060538 skeletal muscle organ development;GO:0048708 astrocyte differentiation;GO:0006486 protein glycosylation;GO:0007009 plasma membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K618-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K619-1", "uniprot_id": [ { "id": "A0A0G2K619_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K619", "type": "external" } ], "mass": 97560.0, "length": 846, "protein_name": "Tubulin tyrosine ligase like 13", "gene_name": "Ttll13", "organism": "Rat", "refseq_name": "tubulin polyglutamylase TTLL13 isoform X2", "refseq_ac": [ { "id": "XP_063118736", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063118736", "type": "external" } ], "gene_names_uniprotkb": "Ttll13", "gene_names_refseq": "RGD1310399; Ttll13", "protein_names_uniprotkb": "Tubulin tyrosine ligase like 13", "protein_names_refseq": "tubulin polyglutamylase TTLL13 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8955332)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070740 tubulin-glutamic acid ligase activity;GO:0005524 ATP binding;GO:0015631 tubulin binding", "go_cellular_component": "GO:0005874 microtubule;GO:0036064 ciliary basal body", "go_biological_process": "GO:0001578 microtubule bundle formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K619-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K620-1", "uniprot_id": [ { "id": "A0A0G2K620_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K620", "type": "external" } ], "mass": 34912.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or9g4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or9g4", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D4AA86", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K620-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K622-1", "uniprot_id": [ { "id": "A0A0G2K622_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K622", "type": "external" } ], "mass": 19739.0, "length": 169, "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "organism": "Rat", "refseq_name": "uncharacterized protein LOC100363294 isoform 1", "refseq_ac": [ { "id": "NP_001257345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257345", "type": "external" } ], "gene_names_uniprotkb": "Slbpl; LOC100363294", "gene_names_refseq": "SLBP2; Slbpl", "protein_names_uniprotkb": "Histone RNA hairpin-binding protein; Histone stem-loop-binding protein", "protein_names_refseq": "stem loop binding protein 2; uncharacterized protein LOC100363294 isoform 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071207 histone pre-mRNA stem-loop binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0071204 histone pre-mRNA 3'end processing complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K622-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K628-1", "uniprot_id": [ { "id": "A0A0G2K628_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K628", "type": "external" } ], "mass": 80316.0, "length": 727, "protein_name": "Ski oncogene", "gene_name": "Ski", "organism": "Rat", "refseq_name": "ski oncogene", "refseq_ac": [ { "id": "NP_001094185", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094185", "type": "external" } ], "gene_names_uniprotkb": "Ski", "gene_names_refseq": "RGD1565591; Ski; c-ski", "protein_names_uniprotkb": "Ski oncogene; Proto-oncogene c-Ski", "protein_names_refseq": "Sloan-Kettering viral oncogene homolog; ski oncogene; ski sarcoma viral oncogene homolog; v-ski avian sarcoma viral oncogene homolog", "tax_id": 10116, "disease": "craniosynostosis (Disease Ontology:DOID:2340)", "pathway": " (R-RNO-201451); (R-RNO-2173795)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "22673903;30488595;33349993;33847835;35007896;35339646", "class_list": "", "function": "SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation. Publication Status: Online-Only, [RefSeq, PubMed]; Ski Regulates the Inflammatory Response of Reactive Astrocytes Induced by Oxygen Glucose Deprivation/Reoxygenation (OGD/R) Through the NF-kappaB Pathway., [RefSeq, PubMed]; Ski overexpression elevates expression and extracellular secretion/release of MMP-9 in primary cardiac myofibroblasts., [RefSeq, PubMed]; Ski promotes proliferation and inhibits apoptosis in fibroblasts under high-glucose conditions via the FoxO1 pathway., [RefSeq, PubMed]; Ski regulates proliferation and migration of reactive astrocytes induced by lipopolysaccharide (LPS) through PI3K/Akt pathway., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046811 histone deacetylase inhibitor activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0017053 transcription repressor complex;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0043585 nose morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030326 embryonic limb morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0G2K628-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K634-1", "uniprot_id": [ { "id": "A0A0G2K634_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K634", "type": "external" } ], "mass": 36928.0, "length": 339, "protein_name": "RAD51 associated protein 1", "gene_name": "Rad51ap1", "organism": "Rat", "refseq_name": "RAD51-associated protein 1 isoform 2", "refseq_ac": [ { "id": "NP_001073179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073179", "type": "external" } ], "gene_names_uniprotkb": "Rad51ap1", "gene_names_refseq": "Rad51ap1", "protein_names_uniprotkb": "RAD51 associated protein 1", "protein_names_refseq": "RAD51-associated protein 1 isoform 2", "tax_id": 10116, "disease": "", "pathway": " (rno:689055); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693568); (R-RNO-5693579)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0000217 DNA secondary structure binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005694 chromosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination;GO:0071479 cellular response to ionizing radiation;GO:0036297 interstrand cross-link repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K634-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K644-1", "uniprot_id": [ { "id": "A0A0G2K644_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K644", "type": "external" } ], "mass": 71528.0, "length": 644, "protein_name": "Synaptotagmin 16", "gene_name": "Syt16", "organism": "Rat", "refseq_name": "synaptotagmin 16 isoform 1", "refseq_ac": [ { "id": "NP_001415561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415561", "type": "external" } ], "gene_names_uniprotkb": "Syt16", "gene_names_refseq": "RGD1564654; Syt16", "protein_names_uniprotkb": "Synaptotagmin 16", "protein_names_refseq": "synaptotagmin 16 isoform 1; synaptotagmin XVI", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042802 identical protein binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K644-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K652-1", "uniprot_id": [ { "id": "A0A0G2K652_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K652", "type": "external" } ], "mass": 283665.0, "length": 2541, "protein_name": "Cullin-9", "gene_name": "Cul9", "organism": "Rat", "refseq_name": "cullin-9 isoform X1", "refseq_ac": [ { "id": "XP_038939436", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038939436", "type": "external" } ], "gene_names_uniprotkb": "Cul9", "gene_names_refseq": "Cul9; Parc; RGD1562008", "protein_names_uniprotkb": "Cullin-9; p53-associated parkin-like cytoplasmic protein", "protein_names_refseq": "cullin-9 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8951664)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0016740 transferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0031461 cullin-RING ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0000226 microtubule cytoskeleton organization;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0007088 regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K652-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K654-1", "uniprot_id": [ { "id": "A0A0G2K654_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K654", "type": "external" } ], "mass": 21317.0, "length": 212, "protein_name": "H1.2 linker histone, cluster member", "gene_name": "H1f2", "organism": "Rat", "refseq_name": "H1.2 linker histone, cluster member", "refseq_ac": [ { "id": "NP_001395696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395696", "type": "external" } ], "gene_names_uniprotkb": "H1f2", "gene_names_refseq": "H1f2; 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Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0002039 p53 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005764 lysosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045087 innate immune response;GO:1900181 negative regulation of protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K659-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K665-1", "uniprot_id": [ { "id": "A0A0G2K665_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K665", "type": "external" } ], "mass": 157602.0, "length": 1387, "protein_name": "GTPase activating protein testicular GAP1", "gene_name": "Tgap1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tgap1; 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Or5b116b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 354; olfactory receptor Olr354; olfactory receptor gene Olr354", "tax_id": 10116, "disease": "", "pathway": " (rno:405931)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6B8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6D1-1", "uniprot_id": [ { "id": "A0A0G2K6D1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6D1", "type": "external" } ], "mass": 133659.0, "length": 1179, "protein_name": "Protein phosphatase 2, regulatory subunit B'', alpha", "gene_name": "Ppp2r3a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ppp2r3a", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein phosphatase 2, regulatory subunit B'', alpha", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:363122)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:0007525 somatic muscle development;GO:0090249 regulation of cell migration involved in somitogenic axis elongation;GO:0001756 somitogenesis;GO:0060828 regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6D1-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6D5-1", "uniprot_id": [ { "id": "A0A0G2K6D5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6D5", "type": "external" } ], "mass": 117421.0, "length": 1035, "protein_name": "Presequence protease, mitochondrial", "gene_name": "Pitrm1", "organism": "Rat", "refseq_name": "presequence protease, mitochondrial isoform 2", "refseq_ac": [ { "id": "NP_001402089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402089", "type": "external" } ], "gene_names_uniprotkb": "Pitrm1", "gene_names_refseq": "Pitrm1", "protein_names_uniprotkb": "Presequence protease, mitochondrial; Pitrilysin metalloproteinase 1", "protein_names_refseq": "pitrilysin metallepetidase 1; pitrilysin metalloprotease 1; presequence protease, mitochondrial isoform 2; presequence protease, mitochondrial", "tax_id": 10116, "disease": "hereditary ataxia (Disease Ontology:DOID:0050951); autosomal recessive spinocerebellar ataxia 30 (Disease Ontology:DOID:0070411); Alzheimer's disease (Disease Ontology:DOID:10652); primary cerebellar degeneration (Disease Ontology:DOID:9277)", "pathway": " (rno:307081); (R-RNO-1268020)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage. Also degrades other unstructured peptides. It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion. It is a highly efficient protease, at least toward amyloid-beta protein 40. Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently. It is also able to degrade amyloid-beta protein 42., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008237 metallopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6D5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6D6-1", "uniprot_id": [ { "id": "A0A0G2K6D6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6D6", "type": "external" } ], "mass": 56921.0, "length": 496, "protein_name": "Origin recognition complex subunit 5", "gene_name": "Orc5", "organism": "Rat", "refseq_name": "origin recognition complex subunit 5 isoform X1", "refseq_ac": [ { "id": "XP_006236009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006236009", "type": "external" } ], "gene_names_uniprotkb": "Orc5; Orc5l", "gene_names_refseq": "Orc5l; Orc5", "protein_names_uniprotkb": "Origin recognition complex subunit 5", "protein_names_refseq": "origin recognition complex subunit 5 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:362304)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0005664 nuclear origin of replication recognition complex;GO:0000808 origin recognition complex", "go_biological_process": "GO:0006275 regulation of DNA replication;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6D6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6D8-1", "uniprot_id": [ { "id": "A0A0G2K6D8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6D8", "type": "external" } ], "mass": 36028.0, "length": 319, "protein_name": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial", "gene_name": "Sirt4", "organism": "Rat", "refseq_name": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial", "refseq_ac": [ { "id": "NP_001100617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100617", "type": "external" } ], "gene_names_uniprotkb": "Sirt4; SIRT4", "gene_names_refseq": "Sirt4", "protein_names_uniprotkb": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; 2.3.1.-; 2.3.1.286; 2.4.2.-; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein biotinylase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; Regulatory protein SIR2 homolog 4; SIR2-like protein 4", "protein_names_refseq": "NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial", "tax_id": 10116, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208)", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "30661205;32865007;33636397", "class_list": "", "function": "Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion., [UniProtKB, HAMAP]; Physiological profile regulation during weight gain and loss by ovariectomized females: importance of SIRT1 and SIRT4., [RefSeq, PubMed]; SIRT4 regulates rat dental papilla cell differentiation by promoting mitochondrial functions., [RefSeq, PubMed]; The association between recovery of olfactory function and the increase in bulbar SIRT1 and SIRT4 expression, is reported., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070403 NAD+ binding;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity;GO:0061690 lipoamidase activity;GO:0034979 NAD-dependent protein lysine deacetylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0046322 negative regulation of fatty acid oxidation;GO:0046889 positive regulation of lipid biosynthetic process;GO:0071456 cellular response to hypoxia;GO:0006974 DNA damage response;GO:0046676 negative regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K6D8-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6E3-1", "uniprot_id": [ { "id": "A0A0G2K6E3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6E3", "type": "external" } ], "mass": 116698.0, "length": 1018, "protein_name": "Myosin IG", "gene_name": "Myo1g", "organism": "Rat", "refseq_name": "unconventional myosin-Ig", "refseq_ac": [ { "id": "NP_001423969", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423969", "type": "external" } ], "gene_names_uniprotkb": "Myo1g", "gene_names_refseq": "Myo1g", "protein_names_uniprotkb": "Myosin IG", "protein_names_refseq": "myosin-Ig; unconventional myosin-Ig", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0030175 filopodium;GO:0031256 leading edge membrane", "go_biological_process": "GO:0006909 phagocytosis;GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006887 exocytosis;GO:0031589 cell-substrate adhesion;GO:0051649 establishment of localization in cell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K6E3-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "uniprot_id": [ { "id": "A0A0G2K6E6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6E6", "type": "external" } ], "mass": 93982.0, "length": 835, "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC120093152", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho GTPase-activating protein 20-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0007283 spermatogenesis;GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6P0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6P4-1", "uniprot_id": [ { "id": "A0A0G2K6P4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6P4", "type": "external" } ], "mass": 24790.0, "length": 214, "protein_name": "High mobility group box 1 like 5", "gene_name": "Hmgb1l1; Hmgb1l5; LOC108350839; LOC134485624", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Hmgb1l1; Hmgb1l5; LOC108350839; LOC134485624; AABR07029613.1; ENSRNOG00000063632; Hmgb1l3; Hmgb1l5; LOC108348989; LOC108350839; LOC134478941; LOC134485624; RGD1563668", "gene_names_refseq": "", "protein_names_uniprotkb": "High mobility group box 1 like 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); Kawasaki disease (Disease Ontology:DOID:13378); alcohol use disorder (Disease Ontology:DOID:1574); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); cerebral infarction (Disease Ontology:DOID:3526); systemic scleroderma (Disease Ontology:DOID:418); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (R-RNO-140342); (R-RNO-3000471); (R-RNO-445989); (R-RNO-5620971); (R-RNO-5686938); (R-RNO-6798695); (R-RNO-879415); (R-RNO-933542)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the cytoplasm proposed to dissociate the BECN1:BCL2 complex via competitive interaction with BECN1 leading to autophagy activation. Can protect BECN1 and ATG5 from calpain-mediated cleavage and thus proposed to control their proautophagic and proapoptotic functions and to regulate the extent and severity of inflammation-associated cellular injury. In myeloid cells has a protective role against endotoxemia and bacterial infection by promoting autophagy. 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subserous uterine fibroid (Disease Ontology:DOID:13560)", "pathway": " (R-RNO-426496)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005654 nucleoplasm;GO:0000932 P-body", "go_biological_process": "GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0035195 miRNA-mediated post-transcriptional gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K6R0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6T6-1", "uniprot_id": [ { "id": "A0A0G2K6T6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6T6", "type": "external" } ], "mass": 186496.0, "length": 1717, "protein_name": "[histone H3]-lysine(4) N-methyltransferase", "gene_name": "Setd1a", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "refseq_ac": [ { "id": "NP_001414023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414023", "type": "external" } ], "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "RGD1311624; Setd1a", "protein_names_uniprotkb": "[histone H3]-lysine(4) N-methyltransferase; 2.1.1.364", "protein_names_refseq": "histone-lysine N-methyltransferase SETD1A", "tax_id": 10116, "disease": "neurodevelopmental disorder with speech impairment and dysmorphic facies (Disease Ontology:DOID:0070417); early-onset epilepsy 2 (Disease Ontology:DOID:0070471); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (R-RNO-3214841); (R-RNO-8936459); (R-RNO-9772755)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" }, { "id": "2.1.1.371", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.371", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.85", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0008013 beta-catenin binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0042800 histone H3K4 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0000785 chromatin;GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:2000648 positive regulation of stem cell proliferation;GO:0010628 positive regulation of gene expression;GO:0007420 brain development;GO:1902036 regulation of hematopoietic stem cell differentiation;GO:0019827 stem cell population maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K6T6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6U0-1", "uniprot_id": [ { "id": "A0A0G2K6U0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6U0", "type": "external" } ], "mass": 34970.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or4c116", "organism": "Rat", "refseq_name": "olfactory receptor Olr678", "refseq_ac": [ { "id": "NP_001000353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000353", "type": "external" } ], "gene_names_uniprotkb": "Or4c116", "gene_names_refseq": "Olr678; Or4c116; ratchr3-73313679-73312744_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 678; olfactory receptor Olr678; olfactory receptor gene Olr678; ratchr3- 73313679-73312744_ORF", "tax_id": 10116, "disease": "", "pathway": " (rno:295884)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6U0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6U7-1", "uniprot_id": [ { "id": "A0A0G2K6U7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6U7", "type": "external" } ], "mass": 80948.0, "length": 743, "protein_name": "NF-kappa-B inhibitor zeta", "gene_name": "Nfkbiz", "organism": "Rat", "refseq_name": "NF-kappa-B inhibitor zeta", "refseq_ac": [ { "id": "NP_001388359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388359", "type": "external" } ], "gene_names_uniprotkb": "Nfkbiz", "gene_names_refseq": "Mail; Nfkbiz; RGD1310834", "protein_names_uniprotkb": "NF-kappa-B inhibitor zeta; I-kappa-B-zeta; IL-1 inducible nuclear ankyrin-repeat protein; Molecule possessing ankyrin repeats induced by lipopolysaccharide", "protein_names_refseq": "IkappaB-zeta; NF-kappa-B inhibitor zeta; molecule possessing ankyrin-repeats induced by lipopolysaccharide; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta", "tax_id": 10116, "disease": "Stevens-Johnson syndrome (Disease Ontology:DOID:0050426); atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "28099916", "class_list": "", "function": "Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Also seems to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR)., [UniProtKB, UniProtKB]; Suggest role for NF-kappaBIZ in age-associated progressive renal fibrosis via cytokine signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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"record_id": "A0A0G2K6U7-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6V2-1", "uniprot_id": [ { "id": "A0A0G2K6V2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V2", "type": "external" } ], "mass": 178330.0, "length": 1560, "protein_name": "[histone H3]-trimethyl-L-lysine(4) demethylase", "gene_name": "Kdm5d", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kdm5d", "gene_names_refseq": "", "protein_names_uniprotkb": "[histone H3]-trimethyl-L-lysine(4) demethylase; 1.14.11.67", "protein_names_refseq": "", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); autism spectrum disorder (Disease Ontology:DOID:0060041); syndromic X-linked intellectual disability Claes-Jensen type (Disease Ontology:DOID:0060809); intellectual disability (Disease Ontology:DOID:1059); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.67", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.67", "type": "external" } ], "go_molecular_function": "GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0032453 histone H3K4 demethylase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0050681 nuclear androgen receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0002457 T cell antigen processing and presentation;GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0060765 regulation of androgen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6V2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "uniprot_id": [ { "id": "A0A0G2K6V9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9", "type": "external" } ], "mass": 55372.0, "length": 493, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2; Smokwl3", "organism": "Rat", "refseq_name": "putative sperm motility kinase W isoform X1", "refseq_ac": [ { "id": "XP_038936382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038936382", "type": "external" } ], "gene_names_uniprotkb": "Smokwl2; Smokwl3; ENSRNOG00000065103; ENSRNOG00000068522; LOC134479633; LOC134479831; RGD1564409; RGD1565071; Smokwl3; Smokwl7", "gene_names_refseq": "Smokwl2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "putative sperm motility kinase W isoform X1", "tax_id": 10116, "disease": "", 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0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", 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Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. 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Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005814 centriole;GO:0032991 protein-containing complex", "go_biological_process": "GO:0046599 regulation of centriole replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K779-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K791-1", "uniprot_id": [ { "id": "A0A0G2K791_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K791", "type": "external" } ], "mass": 7579.0, "length": 64, "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "Mrpl33", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mrpl33", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein bL33m; 39S ribosomal protein L33, mitochondrial", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9937383)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K791-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7A1-1", "uniprot_id": [ { "id": "A0A0G2K7A1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7A1", "type": "external" } ], "mass": 5352.0, "length": 45, "protein_name": "Thymosin beta", "gene_name": "Tmsb15a", "organism": "Rat", "refseq_name": "thymosin beta-15A", "refseq_ac": [ { "id": "NP_001388144", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388144", "type": "external" } ], "gene_names_uniprotkb": "Tmsb15a", "gene_names_refseq": "Tmsb15a", "protein_names_uniprotkb": "Thymosin beta", "protein_names_refseq": "thymosin beta-15A; thymosin-like 8-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003785 actin monomer binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031941 filamentous actin", "go_biological_process": "GO:0007015 actin filament organization;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7A1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7A5-1", "uniprot_id": [ { "id": "A0A0G2K7A5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7A5", "type": "external" } ], "mass": 66647.0, "length": 680, "protein_name": "Collagen type X alpha 1 chain", "gene_name": "Col10a1", "organism": "Rat", "refseq_name": "collagen alpha-1(X) chain precursor", "refseq_ac": [ { "id": "NP_037272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037272", "type": "external" } ], "gene_names_uniprotkb": "Col10a1", "gene_names_refseq": "Col10a1", "protein_names_uniprotkb": "Collagen type X alpha 1 chain", "protein_names_refseq": "collagen alpha-1(X) chain precursor; collagen alpha-1(X) chain; collagen, type X, alpha 1; procollagen, type X, alpha 1", "tax_id": 10116, "disease": "Schmid metaphyseal chondrodysplasia (Disease Ontology:DOID:0080021); osteochondrodysplasia (Disease Ontology:DOID:2256); lung adenocarcinoma (Disease Ontology:DOID:3910); degenerative disc disease (Disease Ontology:DOID:90)", "pathway": " (R-RNO-1442490); (R-RNO-1650814); (R-RNO-2022090); (R-RNO-3000171); (R-RNO-8948216)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030020 extracellular matrix structural constituent conferring tensile strength", "go_cellular_component": "GO:0005576 extracellular region;GO:0005938 cell cortex;GO:0031012 extracellular matrix;GO:0005581 collagen trimer;GO:0005599 collagen type X trimer", "go_biological_process": "GO:0051216 cartilage development;GO:0001958 endochondral ossification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7A5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7D0-1", "uniprot_id": [ { "id": "A0A0G2K7D0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7D0", "type": "external" } ], "mass": 31599.0, "length": 281, "protein_name": "Coiled coil domain containing 28B", "gene_name": "Ccdc28b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ccdc28b", "gene_names_refseq": "", "protein_names_uniprotkb": "Coiled coil domain containing 28B", "protein_names_refseq": "", "tax_id": 10116, "disease": "Bardet-Biedl syndrome 1 (Disease Ontology:DOID:0110123); Bardet-Biedl syndrome (Disease Ontology:DOID:1935)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome", "go_biological_process": "GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7D0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7E7-1", "uniprot_id": [ { "id": "A0A0G2K7E7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7E7", "type": "external" } ], "mass": 7493.0, "length": 68, "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "Sec61gl2", "organism": "Rat", "refseq_name": "protein transport protein Sec61 subunit gamma-like", "refseq_ac": [ { "id": "XP_038952383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038952383", "type": "external" } ], "gene_names_uniprotkb": "Sec61gl2; AABR07028668.1; LOC108348617", "gene_names_refseq": "Sec61gl2", "protein_names_uniprotkb": "Protein transport protein Sec61 subunit gamma", "protein_names_refseq": "protein transport protein Sec61 subunit gamma-like", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0071261 Ssh1 translocon complex", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7E7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7F0-1", "uniprot_id": [ { "id": "A0A0G2K7F0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7F0", "type": "external" } ], "mass": 225106.0, "length": 2017, "protein_name": "RNA helicase", "gene_name": "Fancm", "organism": "Rat", "refseq_name": "Fanconi anemia group M protein", "refseq_ac": [ { "id": "NP_001414592", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414592", "type": "external" } ], "gene_names_uniprotkb": "Fancm", "gene_names_refseq": "Fancm; RGD1307897", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13; ATP-dependent RNA helicase FANCM", "protein_names_refseq": "Fanconi anemia group M protein; Fanconi anemia, complementation group M", "tax_id": 10116, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); primary ovarian insufficiency 15 (Disease Ontology:DOID:0080872); spermatogenic failure 28 (Disease Ontology:DOID:0111916); Fanconi anemia (Disease Ontology:DOID:13636)", "pathway": " (R-RNO-6783310); (R-RNO-9833482)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. This activity is strongly stimulated in the presence of CENPS and CENPX. In complex with FAAP24, efficiently binds to single-strand DNA (ssDNA), splayed-arm DNA, and 3'-flap substrates. In vitro, on its own, strongly binds ssDNA oligomers and weakly fsDNA, but does not bind to dsDNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M0R3Y7", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0031508 pericentric heterochromatin formation;GO:0006338 chromatin remodeling;GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division;GO:0001822 kidney development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K7M6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7N9-1", "uniprot_id": [ { "id": "A0A0G2K7N9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7N9", "type": "external" } ], "mass": 172163.0, "length": 1502, "protein_name": "Rho GTPase-activating protein 5", "gene_name": "Arhgap5", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 5 isoform X2", "refseq_ac": [ { "id": "XP_038967900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038967900", "type": "external" } ], "gene_names_uniprotkb": "Arhgap5", "gene_names_refseq": "Arhgap5; LRRGT00098", "protein_names_uniprotkb": "Rho GTPase-activating protein 5; Rho-type GTPase-activating protein 5; p190-B", "protein_names_refseq": "rho GTPase-activating protein 5 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106); (R-RNO-9013148); (R-RNO-9013149); (R-RNO-9013406); (R-RNO-9013408); (R-RNO-9013409); (R-RNO-9013423); (R-RNO-9035034); (R-RNO-9696264); (R-RNO-9696270); (R-RNO-9696273)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "GTPase-activating protein for Rho family members., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0042169 SH2 domain binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0010631 epithelial cell migration;GO:0016477 cell migration;GO:0007266 Rho protein signal transduction;GO:0010634 positive regulation of epithelial cell migration;GO:0030879 mammary gland development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K7N9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7P2-1", "uniprot_id": [ { "id": "A0A0G2K7P2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7P2", "type": "external" } ], "mass": 107008.0, "length": 950, "protein_name": "PHD finger protein 14", "gene_name": "Phf14", "organism": "Rat", "refseq_name": "PHD finger protein 14 isoform 1", "refseq_ac": [ { "id": "NP_001385837", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385837", "type": "external" } ], "gene_names_uniprotkb": "Phf14", "gene_names_refseq": "Phf14; RGD1563764", "protein_names_uniprotkb": "PHD finger protein 14", "protein_names_refseq": "PHD finger protein 14 isoform 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone-binding protein. Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trimethylated at 'Lys-27' (H3K27me3). Represses PDGFRA expression, thus playing a role in regulation of mesenchymal cell proliferation. Suppresses the expression of CDKN1A/p21 by reducing the level of trimethylation of histone H3 'Lys-4', leading to enhanced proliferation of germinal center B cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0048286 lung alveolus development;GO:0002314 germinal center B cell differentiation;GO:2000584 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K7P2-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7P4-1", "uniprot_id": [ { "id": "A0A0G2K7P4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7P4", "type": "external" } ], "mass": 35268.0, "length": 314, "protein_name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "gene_name": "Naa12; Txnl4a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Naa12; Txnl4a; Naa12; RGD1560212; Txnl4a", "gene_names_refseq": "", "protein_names_uniprotkb": "N-terminal amino-acid N(alpha)-acetyltransferase NatA; 2.3.1.255", "protein_names_refseq": "", "tax_id": 10116, "disease": "Ogden syndrome (Disease Ontology:DOID:0050781); Burn-McKeown syndrome (Disease Ontology:DOID:0080695)", "pathway": " (rno:100911462); (rno:498890)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex)., [UniProtKB, UniProtKB]; Plays role in pre-mRNA splicing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.255", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.255", "type": "external" } ], "go_molecular_function": "GO:1990189 protein N-terminal-serine acetyltransferase activity;GO:1990190 protein-N-terminal-glutamate acetyltransferase activity;GO:0004596 protein-N-terminal amino-acid acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0046540 U4/U6 x U5 tri-snRNP complex;GO:0031415 NatA complex;GO:0071005 U2-type precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7P4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7R4-1", "uniprot_id": [ { "id": "A0A0G2K7R4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7R4", "type": "external" } ], "mass": 34210.0, "length": 304, "protein_name": "Olfactory receptor", "gene_name": "Or9g19", "organism": "Rat", "refseq_name": "olfactory receptor Olr456", "refseq_ac": [ { "id": "NP_001000687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000687", "type": "external" } ], "gene_names_uniprotkb": "Or9g19", "gene_names_refseq": "Olr456; Or9g19", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 456; olfactory receptor Olr456; olfactory receptor gene Olr456", "tax_id": 10116, "disease": "", "pathway": " (rno:404892)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7R4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7S5-1", "uniprot_id": [ { "id": "A0A0G2K7S5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7S5", "type": "external" } ], "mass": 7990.0, "length": 67, "protein_name": "KRAB domain-containing protein", "gene_name": "ENSRNOG00000062563", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000062563", "gene_names_refseq": "", "protein_names_uniprotkb": "KRAB domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7S5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7T0-1", "uniprot_id": [ { "id": "A0A0G2K7T0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7T0", "type": "external" } ], "mass": 45095.0, "length": 423, "protein_name": "Runt-related transcription factor", "gene_name": "Runx3", "organism": "Rat", "refseq_name": "runt-related transcription factor 3 isoform 1", "refseq_ac": [ { "id": "NP_569109", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569109", "type": "external" } ], "gene_names_uniprotkb": "Runx3", "gene_names_refseq": "Runx3", "protein_names_uniprotkb": "Runt-related transcription factor", "protein_names_refseq": "Runt related transcription factor 3; runt-related transcription factor 3 isoform 1; runt-related transcription factor 3", "tax_id": 10116, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); developmental disorder of mental health (Disease Ontology:DOID:0060037); idiopathic scoliosis (Disease Ontology:DOID:0060250); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovary epithelial cancer (Disease Ontology:DOID:2152); ovarian cancer (Disease Ontology:DOID:2394); asthma (Disease Ontology:DOID:2841); endometrial carcinoma (Disease Ontology:DOID:2871); invasive ductal carcinoma (Disease Ontology:DOID:3008); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); papillary thyroid carcinoma (Disease Ontology:DOID:3969); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (R-RNO-8941855); (R-RNO-8941856); (R-RNO-8941858); (R-RNO-8951430); (R-RNO-8951671); (R-RNO-8951936)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "31298391;31603252;32681471;36690210", "class_list": "", "function": "Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX., [UniProtKB, UniProtKB]; RUNX3 protects against acute lung injury by inhibiting the JAK2/STAT3 pathway in rats with severe acute pancreatitis., [RefSeq, PubMed]; RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury., [RefSeq, PubMed]; Runt-related transcription factor 3, mediated by DNA-methyltransferase 1, regulated Schwann cell proliferation and myelination during peripheral nerve regeneration via JAK/STAT signaling pathway., [RefSeq, PubMed]; Sphingosine-1-phosphate receptor 2 modulates pain sensitivity by suppressing the ROS-RUNX3 pathway in a rat model of neuropathy., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", 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"A0A0G2K7T0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7V2-1", "uniprot_id": [ { "id": "A0A0G2K7V2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7V2", "type": "external" } ], "mass": 52005.0, "length": 472, "protein_name": "Gasdermin D like 1", "gene_name": "Gsdmdl1", "organism": "Rat", "refseq_name": "gasdermin D like 1 isoform 1", "refseq_ac": [ { "id": "NP_001424903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424903", "type": "external" } ], "gene_names_uniprotkb": "Gsdmdl1; RGD1359449", "gene_names_refseq": "Gsdmdl1; RGD1359449", "protein_names_uniprotkb": "Gasdermin D like 1", "protein_names_refseq": "gasdermin D like 1 isoform 1; gasdermin domain containing protein RGD1359449", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", 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Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. 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Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "1.14.14.18", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.18", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.94", "type": "external" }, { "id": "6.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0031625 ubiquitin protein ligase binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0085020 protein K6-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K8C5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K8D1-1", "uniprot_id": [ { "id": "A0A0G2K8D1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K8D1", "type": "external" } ], "mass": 59743.0, "length": 518, "protein_name": "Motile sperm domain-containing protein 2", "gene_name": "Mospd2", "organism": "Rat", "refseq_name": "motile sperm domain-containing protein 2", "refseq_ac": [ { "id": "NP_001385656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385656", "type": "external" } ], "gene_names_uniprotkb": "Mospd2", "gene_names_refseq": "Mospd2; RGD1563952", "protein_names_uniprotkb": "Motile sperm domain-containing protein 2", "protein_names_refseq": "motile sperm domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6798695)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. 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Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. 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"protein_name": "TBC1 domain family member 8B", "gene_name": "Tbc1d8b", "organism": "Rat", "refseq_name": "TBC1 domain family member 8B", "refseq_ac": [ { "id": "NP_001388066", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388066", "type": "external" } ], "gene_names_uniprotkb": "Tbc1d8b", "gene_names_refseq": "RGD1563084; Tbc1d8b", "protein_names_uniprotkb": "TBC1 domain family member 8B", "protein_names_refseq": "TBC1 domain family member 8B; TBC1 domain family, member 8B (with GRAM domain)", "tax_id": 10116, "disease": "nephrotic syndrome type 20 (Disease Ontology:DOID:0070357)", "pathway": " (R-RNO-432722)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in vesicular recycling, probably as a RAB11B GTPase-activating protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0003094 glomerular filtration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9M5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9N3-1", "uniprot_id": [ { "id": "A0A0G2K9N3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N3", "type": "external" } ], "mass": 73225.0, "length": 653, "protein_name": "RNA helicase", "gene_name": "Ddx3y", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ddx3y", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "", "tax_id": 10116, "disease": "Sertoli cell-only syndrome (Disease Ontology:DOID:0050457); childhood medulloblastoma (Disease Ontology:DOID:3869)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016020 membrane;GO:0043186 P granule", "go_biological_process": "GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9N3-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9R1-1", "uniprot_id": [ { "id": "A0A0G2K9R1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9R1", "type": "external" } ], "mass": 61294.0, "length": 526, "protein_name": "Zinc finger protein 545", "gene_name": "Zfp82", "organism": "Rat", "refseq_name": "zinc finger protein 82 isoform X3", "refseq_ac": [ { "id": "XP_038949717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038949717", "type": "external" } ], "gene_names_uniprotkb": "Zfp82", "gene_names_refseq": "Zfp82", "protein_names_uniprotkb": "Zinc finger protein 545", "protein_names_refseq": "zinc finger protein 82 isoform X3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9R1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9R2-1", "uniprot_id": [ { "id": "A0A0G2K9R2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9R2", "type": "external" } ], "mass": 73434.0, "length": 643, "protein_name": "Zinc finger protein 202", "gene_name": "Zfp202", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp202", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 202", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0016604 nuclear body;GO:0005694 chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9R2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9R9-1", "uniprot_id": [ { "id": "A0A0G2K9R9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9R9", "type": "external" } ], "mass": 211185.0, "length": 1843, "protein_name": "Proteasome activator complex subunit 4", "gene_name": "Psme4", "organism": "Rat", "refseq_name": "proteasome activator complex subunit 4", "refseq_ac": [ { "id": "NP_001020311", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020311", "type": "external" } ], "gene_names_uniprotkb": "Psme4", "gene_names_refseq": "Psme4", "protein_names_uniprotkb": "Proteasome activator complex subunit 4; Proteasome activator PA200; Protein BLM10 homolog", "protein_names_refseq": "proteasome (prosome, macropain) activator subunit 4; proteasome activator complex subunit 4", "tax_id": 10116, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545)", "pathway": " (rno:498433)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K9R9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9S1-1", "uniprot_id": [ { "id": "A0A0G2K9S1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9S1", "type": "external" } ], "mass": 69093.0, "length": 642, "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "Socs7", "organism": "Rat", "refseq_name": "suppressor of cytokine signaling 7", "refseq_ac": [ { "id": "NP_001413938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001413938", "type": "external" } ], "gene_names_uniprotkb": "Socs7", "gene_names_refseq": "Socs7", "protein_names_uniprotkb": "Suppressor of cytokine signaling 7", "protein_names_refseq": "suppressor of cytokine signaling 7", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0140031 phosphorylation-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031466 Cul5-RING ubiquitin ligase complex", "go_biological_process": "GO:0021799 cerebral cortex radially oriented cell migration;GO:0035556 intracellular signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0045444 fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9S1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9T1-1", "uniprot_id": [ { "id": "A0A0G2K9T1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9T1", "type": "external" } ], "mass": 98793.0, "length": 864, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Itch", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase Itchy homolog", "refseq_ac": [ { "id": "NP_001005887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005887", "type": "external" } ], "gene_names_uniprotkb": "Itch", "gene_names_refseq": "Itch", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase Itchy homolog; itch E3 ubiquitin ligase; itchy E3 ubiquitin protein ligase homolog", "tax_id": 10116, "disease": "Liddle syndrome (Disease Ontology:DOID:0050477)", "pathway": " (R-RNO-1253288); (R-RNO-168638); (R-RNO-2122948); (R-RNO-5610780); (R-RNO-5632684); (R-RNO-5675482); (R-RNO-8939236); (R-RNO-983168)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "26796253;37306338", "class_list": "", "function": "Bone marrow mesenchymal stem cell-derived exosomes carrying E3 ubiquitin ligase ITCH attenuated cardiomyocyte apoptosis by mediating apoptosis signal-regulated kinase-1., [RefSeq, PubMed]; ITCH targets TXNIP for ubiquitin-proteasome degradation in cardiomyocytes and ameliorates reactive oxygen species-induced cardiotoxicity through the thioredoxin system. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" } ], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:1990763 arrestin family protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0034450 ubiquitin-ubiquitin ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:2000646 positive regulation of receptor catabolic process;GO:0031623 receptor internalization;GO:0043066 negative regulation of apoptotic process;GO:0045087 innate immune response;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K9T1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9U0-1", "uniprot_id": [ { "id": "A0A0G2K9U0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9U0", "type": "external" } ], "mass": 35037.0, "length": 311, "protein_name": "Coiled-coil domain containing 24", "gene_name": "Ccdc24", "organism": "Rat", "refseq_name": "coiled-coil domain-containing protein 24 isoform X4", "refseq_ac": [ { "id": "XP_006238772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006238772", "type": "external" } ], "gene_names_uniprotkb": "Ccdc24", "gene_names_refseq": "Ccdc24; RGD1562911", "protein_names_uniprotkb": "Coiled-coil domain containing 24", "protein_names_refseq": "coiled-coil domain-containing protein 24 isoform X4", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0001835 blastocyst hatching", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9U0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9X2-1", "uniprot_id": [ { "id": "A0A0G2K9X2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9X2", "type": "external" } ], "mass": 46284.0, "length": 412, "protein_name": "43 kDa receptor-associated protein of the synapse", "gene_name": "Rapsn", "organism": "Rat", "refseq_name": "43 kDa receptor-associated protein of the synapse isoform 1", "refseq_ac": [ { "id": "NP_001386657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386657", "type": "external" } ], "gene_names_uniprotkb": "Rapsn", "gene_names_refseq": "Rapsn; rapsyn", "protein_names_uniprotkb": "43 kDa receptor-associated protein of the synapse; 43 kDa postsynaptic protein; Acetylcholine receptor-associated 43 kDa protein", "protein_names_refseq": "43 kDa receptor-associated protein of the synapse isoform 1; 43 kDa receptor-associated protein of the synapse; nicotinic acetylcholine receptor-associated 46K protein; receptor-associated protein of the synapse, 43 kDa", "tax_id": 10116, "disease": "congenital myasthenic syndrome 11 (Disease Ontology:DOID:0110675); fetal akinesia deformation sequence syndrome 2 (Disease Ontology:DOID:0111378)", "pathway": " (rno:362161)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12486121", "class_list": "", "function": "Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin., [UniProtKB, UniProtKB]; Rapsyn binds to acetylcholine receptor at the cell surface, and its recruitment is induced by agrin GeneRIF: rapsyn binds to AChR at the cell surface, and its recruitment is induced by agrin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0033130 acetylcholine receptor binding;GO:0043495 membrane-membrane adaptor activity;GO:0035255 ionotropic glutamate receptor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031594 neuromuscular junction;GO:0045202 synapse", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0007528 neuromuscular junction development;GO:0097049 motor neuron apoptotic process;GO:0071340 skeletal muscle acetylcholine-gated channel clustering;GO:1900075 positive regulation of neuromuscular synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K9X2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9X4-1", "uniprot_id": [ { "id": "A0A0G2K9X4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9X4", "type": "external" } ], "mass": 35105.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "Or5h27", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or5h27", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9X4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9Y3-1", "uniprot_id": [ { "id": "A0A0G2K9Y3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9Y3", "type": "external" } ], "mass": 504195.0, "length": 4582, "protein_name": "StAR-related lipid transfer protein 9", "gene_name": "Stard9", "organism": "Rat", "refseq_name": "stAR-related lipid transfer protein 9", "refseq_ac": [ { "id": "NP_001414759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414759", "type": "external" } ], "gene_names_uniprotkb": "Stard9; LOC691920", "gene_names_refseq": "RGD1310448; Stard9", "protein_names_uniprotkb": "StAR-related lipid transfer protein 9; START domain-containing protein 9", "protein_names_refseq": "START domain containing 9-like; StAR-related lipid transfer (START) domain containing 9; stAR-related lipid transfer protein 9", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008289 lipid binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005814 centriole", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0051225 spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K9Y3-1", "record_type": "protein", "filter_code": "0000000.0000100.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9Z9-1", "uniprot_id": [ { "id": "A0A0G2K9Z9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9Z9", "type": "external" } ], "mass": 43036.0, "length": 365, "protein_name": "Killer cell lectin-like receptor subfamily A, member 12-like", "gene_name": "LOC124459649; 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"reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KA19-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KA21-1", "uniprot_id": [ { "id": "A0A0G2KA21_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21", "type": "external" } ], "mass": 48664.0, "length": 457, "protein_name": "One cut domain family member", "gene_name": "Onecut2", "organism": "Rat", "refseq_name": "one cut domain family member 2", "refseq_ac": [ { "id": "NP_001387562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387562", "type": "external" } ], "gene_names_uniprotkb": "Onecut2", "gene_names_refseq": "Onecut2; RGD1564677", "protein_names_uniprotkb": "One cut domain family member", "protein_names_refseq": "one cut domain family member 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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} ], "mass": 35314.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or8k32", "organism": "Rat", "refseq_name": "olfactory receptor Olr507", "refseq_ac": [ { "id": "NP_001000678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000678", "type": "external" } ], "gene_names_uniprotkb": "Or8k32", "gene_names_refseq": "Olr507; Or8k32", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 507; olfactory receptor Olr507; olfactory receptor gene Olr507", "tax_id": 10116, "disease": "", "pathway": " (rno:404881)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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"url": "https://www.uniprot.org/uniprot/A0A0G2KAE3", "type": "external" } ], "mass": 46695.0, "length": 406, "protein_name": "Kelch domain-containing protein 1", "gene_name": "ENSRNOG00000066035; Klhdc1", "organism": "Rat", "refseq_name": "kelch domain-containing protein 1 isoform 1", "refseq_ac": [ { "id": "NP_001401856", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401856", "type": "external" } ], "gene_names_uniprotkb": "ENSRNOG00000066035; Klhdc1; Klhdc1", "gene_names_refseq": "Klhdc1", "protein_names_uniprotkb": "Kelch domain-containing protein 1", "protein_names_refseq": "kelch domain-containing protein 1 isoform 1; kelch domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Substrate-recognition component of a Cul5-RING (CRL5) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. The CRL5(KLHDC1) complex mediates ubiquitination and degradation of truncated SELENOS selenoprotein produced by failed UGA/Sec decoding, which ends with a glycine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031466 Cul5-RING ubiquitin ligase complex", "go_biological_process": "GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAE3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAE6-1", "uniprot_id": [ { "id": "A0A0G2KAE6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAE6", "type": "external" } ], "mass": 65660.0, "length": 593, "protein_name": "Mitoguardin 2", "gene_name": "Miga2", "organism": "Rat", "refseq_name": "mitoguardin 2 isoform 1", "refseq_ac": [ { "id": "NP_001386255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386255", "type": "external" } ], "gene_names_uniprotkb": "Miga2", "gene_names_refseq": "Fam73b; Miga2; RGD1310887", "protein_names_uniprotkb": "Mitoguardin 2; Protein FAM73B", "protein_names_refseq": "family with sequence similarity 73, member B; mitoguardin 2 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:296623); (R-RNO-1483166)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0060348 bone development;GO:0008053 mitochondrial fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAE9-1", "uniprot_id": [ { "id": "A0A0G2KAE9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAE9", "type": "external" } ], "mass": 73975.0, "length": 645, "protein_name": "Outer dynein arm-docking complex subunit 4", "gene_name": "Odad4", "organism": "Rat", "refseq_name": "outer dynein arm-docking complex subunit 4", "refseq_ac": [ { "id": "NP_001100519", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100519", "type": "external" } ], "gene_names_uniprotkb": "Odad4; Ttc25", "gene_names_refseq": "Odad4; RGD1311859; Ttc25", "protein_names_uniprotkb": "Outer dynein arm-docking complex subunit 4; Tetratricopeptide repeat protein 25", "protein_names_refseq": "outer dynein arm-docking complex subunit 4; tetratricopeptide repeat domain 25; tetratricopeptide repeat protein 25", "tax_id": 10116, "disease": "primary ciliary dyskinesia 35 (Disease Ontology:DOID:0110620)", "pathway": " (rno:303534)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Plays an essential role for the assembly of ODA-DC and for the docking of ODA in ciliary axoneme., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005930 axoneme;GO:0097729 9+2 motile cilium;GO:0097728 9+0 motile cilium;GO:0120228 outer dynein arm docking complex", "go_biological_process": "GO:0007507 heart development;GO:0030324 lung development;GO:0007420 brain development;GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAE9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAG4-1", "uniprot_id": [ { "id": "A0A0G2KAG4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAG4", "type": "external" } ], "mass": 21022.0, "length": 187, "protein_name": "FAM3 metabolism regulating signaling molecule B", "gene_name": "Fam3b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fam3b", "gene_names_refseq": "", "protein_names_uniprotkb": "FAM3 metabolism regulating signaling molecule B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0005615 extracellular space", "go_biological_process": "GO:0030073 insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAG4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAH3-1", "uniprot_id": [ { "id": "A0A0G2KAH3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH3", "type": "external" } ], "mass": 49163.0, "length": 446, "protein_name": "T-box transcription factor TBX20", "gene_name": "Tbx20", "organism": "Rat", "refseq_name": "T-box transcription factor TBX20 isoform 1", "refseq_ac": [ { "id": "NP_001388019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388019", "type": "external" } ], "gene_names_uniprotkb": "Tbx20", "gene_names_refseq": "Tbx20", "protein_names_uniprotkb": "T-box transcription factor TBX20", "protein_names_refseq": "T-box 20; T-box transcription factor TBX20 isoform 1; T-box transcription factor TBX20", "tax_id": 10116, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); atrial heart septal defect 4 (Disease Ontology:DOID:0110109); dilated cardiomyopathy (Disease Ontology:DOID:12930); ventricular septal defect (Disease Ontology:DOID:1657); congenital heart disease (Disease Ontology:DOID:1682); atrial heart septal defect (Disease Ontology:DOID:1882); tetralogy of Fallot (Disease Ontology:DOID:6419)", "pathway": " (rno:315497)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26895318;27572266", "class_list": "", "function": "Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart., [UniProtKB, UniProtKB, UniProtKB]; Cardiac TBX20 expression showed a negative correlation with LVEF and a positive correlation with left ventricular end-systolic volume. No significant difference in TBX20 CNVs and promoter methylation was observed between IDCM patients and control group, [RefSeq, PubMed]; Silencing of TBX20 in rat myocardial and human embryonic kidney cells significantly inhibited cell proliferation, induced cell apoptosis and led to G2/M cell cycle arrest., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0001708 cell fate specification;GO:0036302 atrioventricular canal development;GO:0003171 atrioventricular valve development;GO:0060577 pulmonary vein morphogenesis;GO:0003175 tricuspid valve development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KAH3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAH4-1", "uniprot_id": [ { "id": "A0A0G2KAH4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH4", "type": "external" } ], "mass": 233427.0, "length": 2082, "protein_name": "Dedicator of cytokinesis 6", "gene_name": "Dock6", "organism": "Rat", "refseq_name": "dedicator of cytokinesis protein 6 isoform 2", "refseq_ac": [ { "id": "NP_001400840", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400840", "type": "external" } ], "gene_names_uniprotkb": "Dock6", "gene_names_refseq": "Dock6", "protein_names_uniprotkb": "Dedicator of cytokinesis 6", "protein_names_refseq": "dedicator of cytokinesis protein 6 isoform 2; dedicator of cytokinesis protein 6", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Adams-Oliver syndrome (Disease Ontology:DOID:0060227); stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (R-RNO-9013148); (R-RNO-9013149); (R-RNO-983231)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAH4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAH6-1", "uniprot_id": [ { "id": "A0A0G2KAH6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6", "type": "external" } ], "mass": 65326.0, "length": 592, "protein_name": "SRSF protein kinase 3", "gene_name": "Srpk3", "organism": "Rat", "refseq_name": "SRSF protein kinase 3", "refseq_ac": [ { "id": "XP_006229623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229623", "type": "external" } ], "gene_names_uniprotkb": "Srpk3", "gene_names_refseq": "Mssk1; Srpk3; Stk23", "protein_names_uniprotkb": "SRSF protein kinase 3; 2.7.11.1; Muscle-specific serine kinase 1; Serine/arginine-rich protein-specific kinase 3; Serine/threonine-protein kinase 23", "protein_names_refseq": "MSSK1; SFRS protein kinase 3; SRSF protein kinase 3; muscle-specific serine kinase 1; serine arginine rich protein-specific kinase 3; serine/threonine kinase 23; serine/threonine-protein kinase SRPK3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0000245 spliceosomal complex assembly;GO:0060537 muscle tissue development;GO:0007519 skeletal muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAH6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAH7-1", "uniprot_id": [ { "id": "A0A0G2KAH7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7", "type": "external" } ], "mass": 90179.0, "length": 791, "protein_name": "Exostosin-2", "gene_name": "Ext2", "organism": "Rat", "refseq_name": "exostosin-2 isoform 1", "refseq_ac": [ { "id": "NP_001386435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386435", "type": "external" } ], "gene_names_uniprotkb": "Ext2", "gene_names_refseq": "Ext2", "protein_names_uniprotkb": "Exostosin-2; 2.4.1.224; Exostosin glycosyltransferase 2; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "protein_names_refseq": "exostoses (multiple) 2; exostosin 2; exostosin-2 isoform 1", "tax_id": 10116, "disease": "hereditary multiple exostoses (Disease Ontology:DOID:206)", "pathway": " (rno:311215); (R-RNO-2022928)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22339633", "class_list": "", "function": "Ext2 gene is involved in heparan sulfate proteoglycans metabolism., [RefSeq, PubMed]; Glycosyltransferase forming with EXT1 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.224", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.224", "type": "external" }, { "id": "2.4.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.225", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0008375 acetylglucosaminyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0043541 UDP-N-acetylglucosamine transferase complex;GO:1902494 catalytic complex", "go_biological_process": "GO:0051923 sulfation;GO:0000271 polysaccharide biosynthetic process;GO:0008217 regulation of blood pressure;GO:0042311 vasodilation;GO:0060047 heart contraction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAH7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAI3-1", "uniprot_id": [ { "id": "A0A0G2KAI3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAI3", "type": "external" } ], "mass": 54599.0, "length": 492, "protein_name": "Cytochrome P450 2W1", "gene_name": "Cyp2w1", "organism": "Rat", "refseq_name": "cytochrome P450, family 2, subfamily w, polypeptide 1", "refseq_ac": [ { "id": "NP_001414598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414598", "type": "external" } ], "gene_names_uniprotkb": "Cyp2w1", "gene_names_refseq": "Cyp2w1", "protein_names_uniprotkb": "Cytochrome P450 2W1", "protein_names_refseq": "cytochrome P450 2W1; cytochrome P450, family 2, subfamily w, polypeptide 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-211958); (R-RNO-211981)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16426568", "class_list": "", "function": "CYP2W1 is expressed human colonic and adrenal gland neoplasms, but not normal tissue, and is expressed in rat fetal and adult colon, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.13.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.-", "type": "external" } ], "go_molecular_function": "GO:0008401 retinoic acid 4-hydroxylase activity;GO:0005506 iron ion binding;GO:0005503 all-trans retinal binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005788 endoplasmic reticulum lumen;GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006644 phospholipid metabolic process;GO:0006082 organic acid metabolic process;GO:0034653 retinoic acid catabolic process;GO:0046222 aflatoxin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAI4-1", "uniprot_id": [ { "id": "A0A0G2KAI4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAI4", "type": "external" } ], "mass": 34717.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5p78c", "organism": "Rat", "refseq_name": "olfactory receptor Olr268", "refseq_ac": [ { "id": "NP_001000733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000733", "type": "external" } ], "gene_names_uniprotkb": "Or5p78c", "gene_names_refseq": "Olr268; Or5p78c", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 268; olfactory receptor Olr268; olfactory receptor gene Olr268", "tax_id": 10116, "disease": "", "pathway": " (rno:404989)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAI4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAI8-1", "uniprot_id": [ { "id": "A0A0G2KAI8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAI8", "type": "external" } ], "mass": 40371.0, "length": 364, "protein_name": "Developmentally regulated GTP binding protein 2", "gene_name": "Drg2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Drg2", "gene_names_refseq": "", "protein_names_uniprotkb": "Developmentally regulated GTP binding protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAI8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAI9-1", "uniprot_id": [ { "id": "A0A0G2KAI9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAI9", "type": "external" } ], "mass": 32091.0, "length": 284, "protein_name": "Radial spoke head protein 9 homolog", "gene_name": "Rsph9", "organism": "Rat", "refseq_name": "radial spoke head protein 9 homolog", "refseq_ac": [ { "id": "NP_001101675", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101675", "type": "external" } ], "gene_names_uniprotkb": "Rsph9", "gene_names_refseq": "RGD1310693; Rsph9", "protein_names_uniprotkb": "Radial spoke head protein 9 homolog", "protein_names_refseq": "radial spoke head 9 homolog; radial spoke head protein 9 homolog", "tax_id": 10116, "disease": "primary ciliary dyskinesia 12 (Disease Ontology:DOID:0110601)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001534 radial spoke;GO:0031514 motile cilium;GO:0036126 sperm flagellum;GO:0005930 axoneme;GO:0060091 kinocilium", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:1904158 axonemal central apparatus assembly;GO:0044458 motile cilium assembly;GO:0003341 cilium movement;GO:0035082 axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAI9-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAK5-1", "uniprot_id": [ { "id": "A0A0G2KAK5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAK5", "type": "external" } ], "mass": 34769.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5p81", "organism": "Rat", "refseq_name": "olfactory receptor Olr276", "refseq_ac": [ { "id": "NP_001000227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000227", "type": "external" } ], "gene_names_uniprotkb": "Or5p81", "gene_names_refseq": "Olr276; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"https://www.uniprot.org/uniprot/A0A0G2KAX2", "type": "external" } ], "mass": 62821.0, "length": 580, "protein_name": "Trafficking protein particle complex subunit 14", "gene_name": "Trappc14", "organism": "Rat", "refseq_name": "trafficking protein particle complex subunit 14", "refseq_ac": [ { "id": "NP_001020140", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020140", "type": "external" } ], "gene_names_uniprotkb": "Trappc14; RGD1305455", "gene_names_refseq": "Map11; RGD1305455; Trappc14", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 14", "protein_names_refseq": "microtubule associated protein 11; trafficking protein particle complex 14; trafficking protein particle complex subunit 14; uncharacterized protein C7orf43 homolog", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 25 (Disease Ontology:DOID:0051036)", "pathway": " (rno:288545)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", 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"0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAY6-1", "uniprot_id": [ { "id": "A0A0G2KAY6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAY6", "type": "external" } ], "mass": 17914.0, "length": 153, "protein_name": "Rhombotin-2", "gene_name": "Lmo2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lmo2", "gene_names_refseq": "", "protein_names_uniprotkb": "Rhombotin-2; Cysteine-rich protein TTG-2; LIM domain only protein 2; T-cell translocation protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:362176); (R-RNO-8939236)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0046872 metal ion binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0043425 bHLH transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0035162 embryonic hemopoiesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045647 negative regulation of erythrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAY6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB00-1", "uniprot_id": [ { "id": "A0A0G2KB00_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00", "type": "external" } ], "mass": 242570.0, "length": 2167, "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Frem1", "gene_names_refseq": "", "protein_names_uniprotkb": "FRAS1-related extracellular matrix protein 1; Protein QBRICK", "protein_names_refseq": "", "tax_id": 10116, "disease": "chromosome 9p deletion syndrome (Disease Ontology:DOID:0060732); Fraser syndrome (Disease Ontology:DOID:0090001); congenital diaphragmatic hernia (Disease Ontology:DOID:3827)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0005604 basement membrane", "go_biological_process": "GO:0097094 craniofacial suture morphogenesis;GO:0007160 cell-matrix adhesion;GO:0007154 cell communication;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KB00-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB06-1", "uniprot_id": [ { "id": "A0A0G2KB06_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB06", "type": "external" } ], "mass": 44217.0, "length": 391, "protein_name": "mitogen-activated protein kinase", "gene_name": "Mapk11", "organism": "Rat", "refseq_name": "mitogen-activated protein kinase 11", "refseq_ac": [ { "id": "NP_001103002", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103002", "type": "external" } ], "gene_names_uniprotkb": "Mapk11", "gene_names_refseq": "Mapk11; p38beta", "protein_names_uniprotkb": "mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 11", "tax_id": 10116, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (rno:689314); (R-RNO-168638); (R-RNO-171007); (R-RNO-198753); (R-RNO-2559580); (R-RNO-4420097); (R-RNO-450302); (R-RNO-450341); (R-RNO-525793); (R-RNO-5668599); (R-RNO-6804756); (R-RNO-69601)", "pathway_count": 12, "publication_count": 4, "publication_id_list": "17069850;22157753;24465521;34814904", "class_list": "", "function": "Data indicate a functionally active mitochondrial pool of p38beta mitogen activated protein kinase (p38beta MAPK), and that this kinase phosphorylates manganese superoxide dismutase (MnSOD) in an 17beta-estradiol (E2)-dependent manner. Publication Status: Online-Only, [RefSeq, PubMed]; Overexpression of p38beta or Rac1 significantly enhanced (1.9- and 3.9-fold, respectively), the tRA-stimulated NIS expression in MCF-7 cells., [RefSeq, PubMed]; The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas. Publication Status: Online-Only, [RefSeq, PubMed]; Unique ceramide signaling in ischemic and preconditioned hearts involving lipid rafts, which generated a survival signal by differentially associating the p38MAPKalpha and p38MAPKbeta with the caveolin-1 and caveoli-3, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, 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"2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:0010628 positive regulation of gene expression;GO:0035556 intracellular signal transduction;GO:0000165 MAPK cascade;GO:0060348 bone development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2KB06-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB09-1", "uniprot_id": [ { "id": "A0A0G2KB09_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB09", "type": "external" } ], "mass": 41701.0, "length": 365, "protein_name": "Parvin, beta", "gene_name": "Parvb", "organism": "Rat", "refseq_name": "beta-parvin", "refseq_ac": [ { "id": "NP_001128252", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128252", "type": "external" } ], "gene_names_uniprotkb": "Parvb", "gene_names_refseq": "Parvb", "protein_names_uniprotkb": "Parvin, beta", 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"reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0006405 RNA export from nucleus;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KB27-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB30-1", "uniprot_id": [ { "id": "A0A0G2KB30_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB30", "type": "external" } ], "mass": 81073.0, "length": 739, "protein_name": "F-box/LRR-repeat protein 19", 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Mediates RHOA ubiquitination and degradation in a ERK2-dependent manner. Induces RAC1 and RAC3 degradation by the proteasome system and thereby regulates TGFB1-induced E-cadherin down-regulation and cell migration. Also mediates ubiquitination and degradation of IL-33-induced receptor IL1RL1 and subsequently blocks IL-33-mediated apoptosis. Within the nucleus, binds to DNA containing unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Recruits CDK-mediator to chromatin and targets CDK8 to promoters of silent developmental genes leading to induction of these genes during cell differentiation. 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"go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KBC6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "uniprot_id": [ { "id": "LRB3L_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KBC9", "type": "external" } ], "mass": 84944.0, "length": 761, "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "ENSRNOG00000064524; Lilrb1; Lilrb3l; Pira2; Pirb", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000064524; Lilrb1; Lilrb3l; Pira2; Pirb; Lilrb1; Lilrb3l; Pir-A1; Pirb", "gene_names_refseq": "", "protein_names_uniprotkb": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100912456)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10586026", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A2JHX5;A2JHX6", "ec_number_list": [], "go_molecular_function": "GO:0032396 inhibitory MHC class I receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0019221 cytokine-mediated signaling pathway;GO:0002764 immune response-regulating signaling pathway;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KBC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KCH4-1", "uniprot_id": [ { "id": "A0A0G2KCH4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KCH4", "type": "external" } ], "mass": 66012.0, "length": 589, "protein_name": "Kelch-like protein 25", "gene_name": "enc2", "organism": "Zebrafish", "refseq_name": "kelch-like protein 25 isoform X2", "refseq_ac": [ { "id": "XP_009296128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296128", "type": "external" } ], "gene_names_uniprotkb": "enc2", "gene_names_refseq": "enc2", "protein_names_uniprotkb": "Kelch-like protein 25", "protein_names_refseq": "kelch-like protein 25 isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:556885)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3APK6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0016567 protein ubiquitination;GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KCH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KCJ6-1", "uniprot_id": [ { "id": "A0A0G2KCJ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KCJ6", "type": "external" } ], "mass": 60367.0, "length": 564, "protein_name": "BTB (POZ) domain-containing 2b; BTB/POZ domain-containing protein 2", "gene_name": "btbd2b", "organism": "Zebrafish", "refseq_name": "BTB/POZ domain-containing protein 2 isoform X3", "refseq_ac": [ { "id": "XP_005168501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168501", "type": "external" } ], "gene_names_uniprotkb": "btbd2b; LOC555499", "gene_names_refseq": "btbd2b", "protein_names_uniprotkb": "BTB (POZ) domain-containing 2b; BTB/POZ domain-containing protein 2", "protein_names_refseq": "BTB/POZ domain-containing protein 2 isoform X3", "tax_id": 7955, "disease": "", "pathway": " (dre:555499); (R-DRE-8951664); (R-DRE-983168)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGD7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KCJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KCZ7-1", "uniprot_id": [ { "id": "A0A0G2KCZ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KCZ7", "type": "external" } ], "mass": 54220.0, "length": 467, "protein_name": "5-hydroxytryptamine receptor 3A isoform X1; 5-hydroxytryptamine receptor 3A-like", "gene_name": "LOC100334841", "organism": "Zebrafish", "refseq_name": "5-hydroxytryptamine receptor 3A isoform X1", "refseq_ac": [ { "id": "XP_009294780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294780", "type": "external" } ], "gene_names_uniprotkb": "LOC100334841", "gene_names_refseq": "LOC100334841", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 3A isoform X1; 5-hydroxytryptamine receptor 3A-like", "protein_names_refseq": "5-hydroxytryptamine receptor 3A isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334841)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AMI3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0022850 serotonin-gated monoatomic cation channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity;GO:0004888 transmembrane signaling receptor activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection;GO:1902495 transmembrane transporter complex", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport;GO:0140227 serotonin-gated cation-selective signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KCZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KD19-1", "uniprot_id": [ { "id": "A0A0G2KD19_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KD19", "type": "external" } ], "mass": 34780.0, "length": 305, "protein_name": "P2Y purinoceptor 14", "gene_name": "LOC793750", "organism": "Zebrafish", "refseq_name": "P2Y purinoceptor 14", "refseq_ac": [ { "id": "XP_009289706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289706", "type": "external" } ], "gene_names_uniprotkb": "LOC793750", "gene_names_refseq": "LOC793750", "protein_names_uniprotkb": "P2Y purinoceptor 14", "protein_names_refseq": "P2Y purinoceptor 14", "tax_id": 7955, "disease": "", "pathway": " (dre:793750); (R-DRE-417957); (R-DRE-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_009289706.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AI81", "ec_number_list": [], "go_molecular_function": "GO:0045028 G protein-coupled purinergic nucleotide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KD19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KDJ5-1", "uniprot_id": [ { "id": "A0A0G2KDJ5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KDJ5", "type": "external" } ], "mass": 82056.0, "length": 749, "protein_name": "Cartilage oligomeric matrix protein", "gene_name": "comp", "organism": "Zebrafish", "refseq_name": "cartilage oligomeric matrix protein isoform 1 precursor", "refseq_ac": [ { "id": "NP_001313279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313279", "type": "external" } ], "gene_names_uniprotkb": "comp; Tsp-4b; im:7154332; si:ch211-43f4.1; thbs5; wu:fb78h09", "gene_names_refseq": "Tsp-4b; comp; im:7154332; si:ch211-43f4.1; thbs5; wu:fb78h09", "protein_names_uniprotkb": "Cartilage oligomeric matrix protein", "protein_names_refseq": "cartilage oligomeric matrix protein isoform 1 precursor; thrombospondin 5", "tax_id": 7955, "disease": "multiple epiphyseal dysplasia 1 (Disease Ontology:DOID:0070303); carpal tunnel syndrome 2 (Disease Ontology:DOID:0070467); pseudoachondroplasia (Disease Ontology:DOID:0080047); multiple epiphyseal dysplasia (Disease Ontology:DOID:12721); osteochondrodysplasia (Disease Ontology:DOID:2256)", "pathway": " (dre:100318854); (R-DRE-216083)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "16620379;23594743;24905975;27189481;36452329;36755921", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588734.2825607.1, SRR32588733.1338036.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 25, 2025 this sequence version replaced NP_001313279.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8H9", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007155 cell adhesion;GO:1903053 regulation of extracellular matrix organization;GO:0035989 tendon development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0G2KDJ5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KDL6-1", "uniprot_id": [ { "id": "A0A0G2KDL6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KDL6", "type": "external" } ], "mass": 123402.0, "length": 1122, "protein_name": "Photoreceptor cilium actin regulator", "gene_name": "pcare1", "organism": "Zebrafish", "refseq_name": "photoreceptor cilium actin regulator", "refseq_ac": [ { "id": "XP_003200429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200429", "type": "external" } ], "gene_names_uniprotkb": "pcare1", "gene_names_refseq": "pcare1", "protein_names_uniprotkb": "Photoreceptor cilium actin regulator", "protein_names_refseq": "photoreceptor cilium actin regulator", "tax_id": 7955, "disease": "retinitis pigmentosa 54 (Disease Ontology:DOID:0110364)", "pathway": " (dre:100537793)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200429.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RJ77", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0060041 retina development in camera-type eye;GO:0042461 photoreceptor cell development;GO:0021549 cerebellum development;GO:0050908 detection of light stimulus involved in visual perception;GO:0060026 convergent extension", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KDL6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KDN7-1", "uniprot_id": [ { "id": "A0A0G2KDN7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KDN7", "type": "external" } ], "mass": 15150.0, "length": 139, "protein_name": "Cold shock domain containing C2, RNA binding b; Cold shock domain-containing protein C2", "gene_name": "csdc2b", "organism": "Zebrafish", "refseq_name": "cold shock domain-containing protein C2", "refseq_ac": [ { "id": "XP_005170841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170841", "type": "external" } ], "gene_names_uniprotkb": "csdc2b", "gene_names_refseq": "csdc2b", "protein_names_uniprotkb": "Cold shock domain containing C2, RNA binding b; Cold shock domain-containing protein C2", "protein_names_refseq": "cold shock domain-containing protein C2", "tax_id": 7955, "disease": "", "pathway": " (dre:557375)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_005170841.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BI40", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0043488 regulation of mRNA stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KDN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KE12-1", "uniprot_id": [ { "id": "A0A0G2KE12_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KE12", "type": "external" } ], "mass": 40479.0, "length": 356, "protein_name": "Oocyte zinc finger protein XlCOF26-like; Zinc finger protein OZF", "gene_name": "LOC100332787", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_002660733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660733", "type": "external" } ], "gene_names_uniprotkb": "LOC100332787", "gene_names_refseq": "LOC100332787", "protein_names_uniprotkb": "Oocyte zinc finger protein XlCOF26-like; Zinc finger protein OZF", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002660733.2. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDA9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KE12-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KEG5-1", "uniprot_id": [ { "id": "A0A0G2KEG5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KEG5", "type": "external" } ], "mass": 36099.0, "length": 312, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "parp11", "organism": "Zebrafish", "refseq_name": "protein mono-ADP-ribosyltransferase PARP11", "refseq_ac": [ { "id": "XP_009299254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299254", "type": "external" } ], "gene_names_uniprotkb": "parp11; LOC103910991", "gene_names_refseq": "parp11", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "protein mono-ADP-ribosyltransferase PARP11", "tax_id": 7955, "disease": "", "pathway": " (dre:103910991)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AZ38", "ec_number_list": [], "go_molecular_function": "GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KEG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KF98-1", "uniprot_id": [ { "id": "A0A0G2KF98_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KF98", "type": "external" } ], "mass": 36852.0, "length": 318, "protein_name": "Zinc finger protein 239-like; Zinc finger protein 570", "gene_name": "LOC101883087", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_005174664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174664", "type": "external" } ], "gene_names_uniprotkb": "LOC101883087", "gene_names_refseq": "LOC101883087", "protein_names_uniprotkb": "Zinc finger protein 239-like; Zinc finger protein 570", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:101883087)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLT5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KF98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KFP7-1", "uniprot_id": [ { "id": "A0A0G2KFP7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KFP7", "type": "external" } ], "mass": 80257.0, "length": 749, "protein_name": "Metal regulatory transcription factor 1", "gene_name": "mtf1", "organism": "Zebrafish", "refseq_name": "metal regulatory transcription factor 1 isoform X1", "refseq_ac": [ { "id": "XP_021322285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322285", "type": "external" } ], "gene_names_uniprotkb": "mtf1; MTF-1", "gene_names_refseq": "MTF-1; mtf1", "protein_names_uniprotkb": "Metal regulatory transcription factor 1; MRE-binding transcription factor; Transcription factor MTF-1", "protein_names_refseq": "metal regulatory transcription factor 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:195821)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11007174;11866436;17269467;18186356;18639347;19021535;23594743;24751692;30690405;30904762;31158555;37001786;37407555", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Zinc-dependent transcriptional regulator of cellular adaption to conditions of exposure to heavy metals. Binds to metal responsive elements (MRE) in promoters and activates the transcription of metallothionein genes like metallothionein-2/MT2A. Also regulates the expression of metalloproteases in response to intracellular zinc and functions as a catabolic regulator of cartilages., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PM66", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0010043 response to zinc ion;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046686 response to cadmium ion;GO:0071276 cellular response to cadmium ion;GO:0071294 cellular response to zinc ion", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "A0A0G2KFP7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KG91-1", "uniprot_id": [ { "id": "A0A0G2KG91_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KG91", "type": "external" } ], "mass": 24735.0, "length": 230, "protein_name": "Linker for activation of T cells; Linker for activation of T-cells family member 1", "gene_name": "lat", "organism": "Zebrafish", "refseq_name": "linker for activation of T-cells family member 1", "refseq_ac": [ { "id": "NP_001137156", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137156", "type": "external" } ], "gene_names_uniprotkb": "lat", "gene_names_refseq": "lat", "protein_names_uniprotkb": "Linker for activation of T cells; Linker for activation of T-cells family member 1", "protein_names_refseq": "linker for activation of T-cells family member 1", "tax_id": 7955, "disease": "IgG4-related disease (Disease Ontology:DOID:0080356); immunodeficiency 52 (Disease Ontology:DOID:0111983)", "pathway": " (dre:100233211)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;28965845;30111845", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CN501380.1, CO927778.1 and EH459415.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NST8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KG91-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KGF4-1", "uniprot_id": [ { "id": "A0A0G2KGF4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KGF4", "type": "external" } ], "mass": 128435.0, "length": 1168, "protein_name": "Transmembrane protein 132C; Transmembrane protein 132D", "gene_name": "LOC100332191", "organism": "Zebrafish", "refseq_name": "transmembrane protein 132D", "refseq_ac": [ { "id": "XP_021334148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334148", "type": "external" } ], "gene_names_uniprotkb": "LOC100332191", "gene_names_refseq": "LOC100332191", "protein_names_uniprotkb": "Transmembrane protein 132C; Transmembrane protein 132D", "protein_names_refseq": "transmembrane protein 132D", "tax_id": 7955, "disease": "", "pathway": " (dre:100332191)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q401", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KGF4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KGX6-1", "uniprot_id": [ { "id": "A0A0G2KGX6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KGX6", "type": "external" } ], "mass": 48237.0, "length": 420, "protein_name": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein 1040", "gene_name": "znf1040", "organism": "Zebrafish", "refseq_name": "uncharacterized protein znf1040", "refseq_ac": [ { "id": "XP_017211075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211075", "type": "external" } ], "gene_names_uniprotkb": "znf1040", "gene_names_refseq": "znf1040", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein 1040", "protein_names_refseq": "uncharacterized protein znf1040", "tax_id": 7955, "disease": "", "pathway": " (dre:101884948)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z6D2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KGX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KH00-1", "uniprot_id": [ { "id": "A0A0G2KH00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KH00", "type": "external" } ], "mass": 47851.0, "length": 421, "protein_name": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein ZFP2", "gene_name": "LOC572670", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_021324621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324621", "type": "external" } ], "gene_names_uniprotkb": "LOC572670", "gene_names_refseq": "LOC572670", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein ZFP2", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:572670)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PQQ9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KH00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KH34-1", "uniprot_id": [ { "id": "A0A0G2KH34_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KH34", "type": "external" } ], "mass": 28320.0, "length": 251, "protein_name": "T-cell leukemia homeobox protein 3", "gene_name": "tlx3a", "organism": "Zebrafish", "refseq_name": "T-cell leukemia homeobox protein 3", "refseq_ac": [ { "id": "XP_003199819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199819", "type": "external" } ], "gene_names_uniprotkb": "tlx3a; LOC100008066", "gene_names_refseq": "tlx3a", "protein_names_uniprotkb": "T-cell leukemia homeobox protein 3", "protein_names_refseq": "T-cell leukemia homeobox protein 3", "tax_id": 7955, "disease": "", "pathway": " (dre:100008066)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFB9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KH34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KHZ9-1", "uniprot_id": [ { "id": "A0A0G2KHZ9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KHZ9", "type": "external" } ], "mass": 32147.0, "length": 277, "protein_name": "Ceramide synthase; TLC domain-containing 3A", "gene_name": "tlcd3a", "organism": "Zebrafish", "refseq_name": "ceramide synthase", "refseq_ac": [ { "id": "XP_005172081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172081", "type": "external" } ], "gene_names_uniprotkb": "tlcd3a", "gene_names_refseq": "tlcd3a", "protein_names_uniprotkb": "Ceramide synthase; TLC domain-containing 3A", "protein_names_refseq": "ceramide synthase", "tax_id": 7955, "disease": "", "pathway": " (dre:100002814)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_005172081.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJV5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KHZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KI21-1", "uniprot_id": [ { "id": "A0A0G2KI21_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KI21", "type": "external" } ], "mass": 33768.0, "length": 292, "protein_name": "Uncharacterized LOC567472; Uncharacterized protein LOC567472", "gene_name": "LOC567472", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC567472", "refseq_ac": [ { "id": "NP_001122013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122013", "type": "external" } ], "gene_names_uniprotkb": "LOC567472", "gene_names_refseq": "LOC567472", "protein_names_uniprotkb": "Uncharacterized LOC567472; Uncharacterized protein LOC567472", "protein_names_refseq": "uncharacterized protein LOC567472", "tax_id": 7955, "disease": "", "pathway": " (dre:567472)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DV591120.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from AL935065.8. On Jul 31, 2008 this sequence version replaced XP_706411.3., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NHN8", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007259 cell surface receptor signaling pathway via JAK-STAT", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KI21-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "uniprot_id": [ { "id": "A0A0G2KIH5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KIH5", "type": "external" } ], "mass": 39240.0, "length": 346, "protein_name": "Major histocompatibility complex class I LLA", "gene_name": "mhc1lla", "organism": "Zebrafish", "refseq_name": "major histocompatibility complex class I LLA precursor", "refseq_ac": [ { "id": "NP_001314818", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314818", "type": "external" } ], "gene_names_uniprotkb": "mhc1lla; si:dkey-52p2.4", "gene_names_refseq": "mhc1lla; si:dkey-52p2.4", "protein_names_uniprotkb": "Major histocompatibility complex class I LLA", "protein_names_refseq": "major histocompatibility complex class I LLA precursor; zinc-alpha-2-glycoprotein-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100536492); (R-DRE-1236974); (R-DRE-1236977); (R-DRE-6798695); (R-DRE-917977); (R-DRE-983170)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "23594743;24631581;30290758", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.26644087.1, SRR32588722.18234906.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA708836, SAMN06350655 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On May 27, 2016 this sequence version replaced XP_009296130.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8G2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KIH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KIJ4-1", "uniprot_id": [ { "id": "A0A0G2KIJ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KIJ4", "type": "external" } ], "mass": 63891.0, "length": 557, "protein_name": "Uncharacterized protein LOC795664 precursor; Wu:fa56d06", "gene_name": "fa56d06", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC795664 precursor", "refseq_ac": [ { "id": "NP_001275704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001275704", "type": "external" } ], "gene_names_uniprotkb": "fa56d06; wu:fa56d06", "gene_names_refseq": "fa56d06; wu:fa56d06", "protein_names_uniprotkb": "Uncharacterized protein LOC795664 precursor; Wu:fa56d06", "protein_names_refseq": "uncharacterized protein LOC795664 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:795664)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH497702.1, EH498242.1, EB878173.1, EB877062.1 and EH506357.1. On Jan 4, 2014 this sequence version replaced XP_001335916.3., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P0F1", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KIJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KIM8-1", "uniprot_id": [ { "id": "A0A0G2KIM8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KIM8", "type": "external" } ], "mass": 96694.0, "length": 870, "protein_name": "Basonuclin 1; Zinc finger protein basonuclin-1 isoform X1", "gene_name": "bnc1", "organism": "Zebrafish", "refseq_name": "zinc finger protein basonuclin-1 isoform X1", "refseq_ac": [ { "id": "XP_009299269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299269", "type": "external" } ], "gene_names_uniprotkb": "bnc1", "gene_names_refseq": "bnc1", "protein_names_uniprotkb": "Basonuclin 1; Zinc finger protein basonuclin-1 isoform X1", "protein_names_refseq": "zinc finger protein basonuclin-1 isoform X1", "tax_id": 7955, "disease": "primary ovarian insufficiency 16 (Disease Ontology:DOID:0080873)", "pathway": " (dre:568786)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ARZ4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006356 regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KIM8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KIS6-1", "uniprot_id": [ { "id": "A0A0G2KIS6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KIS6", "type": "external" } ], "mass": 50733.0, "length": 455, "protein_name": "Histamine H3 receptor", "gene_name": "LOC100334962", "organism": "Zebrafish", "refseq_name": "histamine H3 receptor", "refseq_ac": [ { "id": "XP_003200969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200969", "type": "external" } ], "gene_names_uniprotkb": "LOC100334962", "gene_names_refseq": "LOC100334962", "protein_names_uniprotkb": "Histamine H3 receptor", "protein_names_refseq": "histamine H3 receptor", "tax_id": 7955, "disease": "", "pathway": " (dre:100334962); (R-DRE-390650); (R-DRE-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RP71", "ec_number_list": [], "go_molecular_function": "GO:0030594 neurotransmitter receptor activity;GO:0004969 histamine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KIS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KIZ8-1", "uniprot_id": [ { "id": "DNAI3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KIZ8", "type": "external" } ], "mass": 110941.0, "length": 968, "protein_name": "Dynein axonemal intermediate chain 3", "gene_name": "dnai3", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "dnai3; wdr63", "gene_names_refseq": "", "protein_names_uniprotkb": "Dynein axonemal intermediate chain 3; WD repeat domain 63", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23594743;29285825", "class_list": "", "function": "May be involved in the regulation of cilia function., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0036156 inner dynein arm", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0003341 cilium movement;GO:0036159 inner dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KIZ8-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KJ86-1", "uniprot_id": [ { "id": "A0A0G2KJ86_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KJ86", "type": "external" } ], "mass": 25064.0, "length": 230, "protein_name": "Clarin-3", "gene_name": "clrn3", "organism": "Zebrafish", "refseq_name": "clarin-3", "refseq_ac": [ { "id": "XP_001340685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340685", "type": "external" } ], "gene_names_uniprotkb": "clrn3", "gene_names_refseq": "clrn3", "protein_names_uniprotkb": "Clarin-3", "protein_names_refseq": "clarin-3", "tax_id": 7955, "disease": "", "pathway": " (dre:100000502)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q7K0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KJ86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KJW7-1", "uniprot_id": [ { "id": "A0A0G2KJW7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KJW7", "type": "external" } ], "mass": 35425.0, "length": 317, "protein_name": "folate gamma-glutamyl hydrolase", "gene_name": "LOC553228", "organism": "Zebrafish", "refseq_name": "gamma-glutamyl hydrolase precursor", "refseq_ac": [ { "id": "NP_001243151", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243151", "type": "external" } ], "gene_names_uniprotkb": "LOC553228", "gene_names_refseq": "LOC553228", "protein_names_uniprotkb": "folate gamma-glutamyl hydrolase; 3.4.19.9", "protein_names_refseq": "gamma-glutamyl hydrolase precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:553228)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC076459.1, BC124118.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505381, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076459.1. On Jan 14, 2012 this sequence version replaced XP_002663735.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NYZ6", "ec_number_list": [ { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" } ], "go_molecular_function": "GO:0034722 gamma-glutamyl-peptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005773 vacuole", "go_biological_process": "GO:0046900 tetrahydrofolylpolyglutamate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KJW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KKC2-1", "uniprot_id": [ { "id": "A0A0G2KKC2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KKC2", "type": "external" } ], "mass": 100203.0, "length": 890, "protein_name": "Metal transporter", "gene_name": "cnnm1", "organism": "Zebrafish", "refseq_name": "metal transporter CNNM1 precursor", "refseq_ac": [ { "id": "NP_001315457", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315457", "type": "external" } ], "gene_names_uniprotkb": "cnnm1; si:dkeyp-22h2.1", "gene_names_refseq": "cnnm1; si:dkeyp-22h2.1", "protein_names_uniprotkb": "Metal transporter", "protein_names_refseq": "metal transporter CNNM1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:562504)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01023543.1, SRR32588718.43655692.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 25, 2025 this sequence version replaced NP_001315457.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Metal transporter., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P517", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0010960 magnesium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KKC2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KKG9-1", "uniprot_id": [ { "id": "A0A0G2KKG9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KKG9", "type": "external" } ], "mass": 40971.0, "length": 365, "protein_name": "Bone morphogenetic protein 7; Growth/differentiation factor 6-A-like", "gene_name": "LOC101885590", "organism": "Zebrafish", "refseq_name": "bone morphogenetic protein 7", "refseq_ac": [ { "id": "XP_005172423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172423", "type": "external" } ], "gene_names_uniprotkb": "LOC101885590", "gene_names_refseq": "LOC101885590", "protein_names_uniprotkb": "Bone morphogenetic protein 7; Growth/differentiation factor 6-A-like", "protein_names_refseq": "bone morphogenetic protein 7", "tax_id": 7955, "disease": "", "pathway": " (dre:101885590)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJR0", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KKG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KL77-1", "uniprot_id": [ { "id": "A0A0G2KL77_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KL77", "type": "external" } ], "mass": 41832.0, "length": 365, "protein_name": "Major histocompatibility complex class I-related gene protein", "gene_name": "LOC108181672", "organism": "Zebrafish", "refseq_name": "major histocompatibility complex class I-related gene protein isoform X2", "refseq_ac": [ { "id": "XP_017209800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209800", "type": "external" } ], "gene_names_uniprotkb": "LOC108181672", "gene_names_refseq": "LOC108181672", "protein_names_uniprotkb": "Major histocompatibility complex class I-related gene protein", "protein_names_refseq": "major histocompatibility complex class I-related gene protein isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:108181672)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YYM3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KL77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KLD8-1", "uniprot_id": [ { "id": "A0A0G2KLD8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KLD8", "type": "external" } ], "mass": 31172.0, "length": 277, "protein_name": "Biphenyl hydrolase like; Valacyclovir hydrolase", "gene_name": "bphl", "organism": "Zebrafish", "refseq_name": "valacyclovir hydrolase", "refseq_ac": [ { "id": "NP_001268390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268390", "type": "external" } ], "gene_names_uniprotkb": "bphl", "gene_names_refseq": "bphl", "protein_names_uniprotkb": "Biphenyl hydrolase like; Valacyclovir hydrolase", "protein_names_refseq": "biphenyl hydrolase-like (serine hydrolase); valacyclovir hydrolase", "tax_id": 7955, "disease": "", "pathway": " (dre:402804)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH537883.1, EH538522.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH537883.1, EH538522.1 and EH559743.1. On Aug 31, 2013 this sequence version replaced XP_005174600.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NZX1", "ec_number_list": [], "go_molecular_function": "GO:0017171 serine hydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KLD8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KLK6-1", "uniprot_id": [ { "id": "A0A0G2KLK6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KLK6", "type": "external" } ], "mass": 166885.0, "length": 1551, "protein_name": "DNA-binding protein RFX7 isoform X1; Regulatory factor X7b", "gene_name": "rfx7b", "organism": "Zebrafish", "refseq_name": "DNA-binding protein RFX7 isoform X1", "refseq_ac": [ { "id": "XP_003201650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201650", "type": "external" } ], "gene_names_uniprotkb": "rfx7b; LOC100538179", "gene_names_refseq": "rfx7b", "protein_names_uniprotkb": "DNA-binding protein RFX7 isoform X1; Regulatory factor X7b", "protein_names_refseq": "DNA-binding protein RFX7 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100538179)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003201650.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RJN6", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KLK6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KLM8-1", "uniprot_id": [ { "id": "A0A0G2KLM8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KLM8", "type": "external" } ], "mass": 33776.0, "length": 293, "protein_name": "Zinc finger protein 1117", "gene_name": "znf1117", "organism": "Zebrafish", "refseq_name": "zinc finger protein 1117", "refseq_ac": [ { "id": "NP_001314925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314925", "type": "external" } ], "gene_names_uniprotkb": "znf1117; si:dkey-238o14.9", "gene_names_refseq": "si:dkey-238o14.9; znf1117", "protein_names_uniprotkb": "Zinc finger protein 1117", "protein_names_refseq": "zinc finger protein 1117", "tax_id": 7955, "disease": "", "pathway": " (dre:565962); (R-DRE-9843940)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155233.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505382, SAMEA3505387 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX088547.12. On Jun 2, 2016 this sequence version replaced XP_005168111.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9Q9;E7F4X1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KLM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KLU8-1", "uniprot_id": [ { "id": "A0A0G2KLU8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KLU8", "type": "external" } ], "mass": 33091.0, "length": 301, "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "slc25a29", "organism": "Zebrafish", "refseq_name": "mitochondrial basic amino acids transporter", "refseq_ac": [ { "id": "XP_002665132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665132", "type": "external" } ], "gene_names_uniprotkb": "slc25a29; LOC100329459", "gene_names_refseq": "slc25a29l", "protein_names_uniprotkb": "Mitochondrial basic amino acids transporter; Carnitine/acylcarnitine translocase-like; Mitochondrial carnitine/acylcarnitine carrier protein CACL; Mitochondrial ornithine transporter 3; Solute carrier family 25 member 29", "protein_names_refseq": "mitochondrial basic amino acids transporter", "tax_id": 7955, "disease": "", "pathway": " (dre:100329459)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002665132.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RRK0", "ec_number_list": [], "go_molecular_function": "GO:0005289 high-affinity L-arginine transmembrane transporter activity;GO:0005292 high-affinity lysine transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1990575 mitochondrial L-ornithine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KLU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KM47-1", "uniprot_id": [ { "id": "A0A0G2KM47_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KM47", "type": "external" } ], "mass": 10511.0, "length": 96, "protein_name": "C-X-C motif chemokine 11-6-like", "gene_name": "cxcl11.4", "organism": "Zebrafish", "refseq_name": "C-X-C motif chemokine 11-6-like", "refseq_ac": [ { "id": "XP_696046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696046", "type": "external" } ], "gene_names_uniprotkb": "cxcl11.4; LOC567656", "gene_names_refseq": "cxcl11.4", "protein_names_uniprotkb": "C-X-C motif chemokine 11-6-like", "protein_names_refseq": "C-X-C motif chemokine 11-6-like", "tax_id": 7955, "disease": "pulmonary sarcoidosis (Disease Ontology:DOID:13406); bronchiolitis obliterans (Disease Ontology:DOID:2799); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (dre:567656)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UTC7", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006952 defense response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KM47-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KM96-1", "uniprot_id": [ { "id": "A0A0G2KM96_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KM96", "type": "external" } ], "mass": 45693.0, "length": 413, "protein_name": "ATP-sensitive inward rectifier potassium channel 10", "gene_name": "kcnj10b", "organism": "Zebrafish", "refseq_name": "ATP-sensitive inward rectifier potassium channel 10", "refseq_ac": [ { "id": "XP_009297229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297229", "type": "external" } ], "gene_names_uniprotkb": "kcnj10b; LOC100329607", "gene_names_refseq": "kcnj10b", "protein_names_uniprotkb": "ATP-sensitive inward rectifier potassium channel 10", "protein_names_refseq": "ATP-sensitive inward rectifier potassium channel 10", "tax_id": 7955, "disease": "", "pathway": " (dre:100329607)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A286Y987;A0A8M3AXM2", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0007399 nervous system development;GO:0034765 regulation of monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane;GO:0043009 chordate embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KM96-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KMQ4-1", "uniprot_id": [ { "id": "A0A0G2KMQ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KMQ4", "type": "external" } ], "mass": 45533.0, "length": 393, "protein_name": "Gastrula zinc finger protein XlCGF57.1; Zinc finger protein 239-like", "gene_name": "LOC557537", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_068073909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073909", "type": "external" } ], "gene_names_uniprotkb": "LOC557537", "gene_names_refseq": "LOC557537", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1; Zinc finger protein 239-like", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:557537)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B4I8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KMQ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KN81-1", "uniprot_id": [ { "id": "A0A0G2KN81_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KN81", "type": "external" } ], "mass": 57847.0, "length": 511, "protein_name": "Serine/threonine-protein kinase receptor", "gene_name": "acvr2bb", "organism": "Zebrafish", "refseq_name": "activin receptor type-2B", "refseq_ac": [ { "id": "XP_002667626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667626", "type": "external" } ], "gene_names_uniprotkb": "acvr2bb; LOC100331938", "gene_names_refseq": "acvr2bb", "protein_names_uniprotkb": "Serine/threonine-protein kinase receptor; 2.7.11.30", "protein_names_refseq": "activin receptor type-2B", "tax_id": 7955, "disease": "", "pathway": " (dre:100331938)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RN24", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0048185 activin binding;GO:0017002 activin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048179 activin receptor complex", "go_biological_process": "GO:0071363 cellular response to growth factor stimulus;GO:0032924 activin receptor signaling pathway;GO:0007389 pattern specification process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KN81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KNS1-1", "uniprot_id": [ { "id": "A0A0G2KNS1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KNS1", "type": "external" } ], "mass": 17787.0, "length": 158, "protein_name": "2.8.1.1; Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1", "gene_name": "LOC561325", "organism": "Zebrafish", "refseq_name": "thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 precursor", "refseq_ac": [ { "id": "NP_001313378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313378", "type": "external" } ], "gene_names_uniprotkb": "LOC561325", "gene_names_refseq": "LOC561325", "protein_names_uniprotkb": "2.8.1.1; Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1", "protein_names_refseq": "thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:561325)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC159243.1, GDQQ01008280.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and BC159243.1. On May 18, 2016 this sequence version replaced XP_005168660.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2N7", "ec_number_list": [], "go_molecular_function": "GO:0004792 thiosulfate-cyanide sulfurtransferase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KNS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KNT1-1", "uniprot_id": [ { "id": "A0A0G2KNT1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KNT1", "type": "external" } ], "mass": 26604.0, "length": 236, "protein_name": "DPY30 domain-containing 2", "gene_name": "dydc2", "organism": "Zebrafish", "refseq_name": "DPY30 domain containing 2", "refseq_ac": [ { "id": "NP_001314939", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314939", "type": "external" } ], "gene_names_uniprotkb": "dydc2", "gene_names_refseq": "dydc2", "protein_names_uniprotkb": "DPY30 domain-containing 2", "protein_names_refseq": "DPY30 domain containing 2; DPY30 domain-containing protein 1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100000753)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH468492.1, ERR6511330.1096912.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505383 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1, EH442612.1 and EH468492.1. On Jun 2, 2016 this sequence version replaced XP_001340896.4., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9R3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KNT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KPB1-1", "uniprot_id": [ { "id": "A0A0G2KPB1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KPB1", "type": "external" } ], "mass": 37262.0, "length": 329, "protein_name": "GTPase IMAP family member 8", "gene_name": "LOC571582", "organism": "Zebrafish", "refseq_name": "GTPase IMAP family member 7", "refseq_ac": [ { "id": "XP_005171679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171679", "type": "external" } ], "gene_names_uniprotkb": "LOC571582", "gene_names_refseq": "LOC571582", "protein_names_uniprotkb": "GTPase IMAP family member 8; Immune-associated nucleotide-binding protein 9", "protein_names_refseq": "GTPase IMAP family member 7", "tax_id": 7955, "disease": "", "pathway": " (dre:571582)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BIY0", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KPB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KPL0-1", "uniprot_id": [ { "id": "A0A0G2KPL0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KPL0", "type": "external" } ], "mass": 50462.0, "length": 436, "protein_name": "Galactose-3-O-sulfotransferase 2 isoform X1; Galactose-3-O-sulfotransferase 2-like", "gene_name": "LOC101884228", "organism": "Zebrafish", "refseq_name": "galactose-3-O-sulfotransferase 2 isoform X1", "refseq_ac": [ { "id": "XP_009302113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302113", "type": "external" } ], "gene_names_uniprotkb": "LOC101884228", "gene_names_refseq": "LOC101884228", "protein_names_uniprotkb": "Galactose-3-O-sulfotransferase 2 isoform X1; Galactose-3-O-sulfotransferase 2-like", "protein_names_refseq": "galactose-3-O-sulfotransferase 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101884228)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BBN5", "ec_number_list": [], "go_molecular_function": "GO:0050694 galactose 3-O-sulfotransferase activity;GO:0001733 galactosylceramide sulfotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0009247 glycolipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KPL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KQA6-1", "uniprot_id": [ { "id": "A0A0G2KQA6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KQA6", "type": "external" } ], "mass": 48579.0, "length": 420, "protein_name": "Septin", "gene_name": "sept4b", "organism": "Zebrafish", "refseq_name": "septin 4b", "refseq_ac": [ { "id": "NP_001315432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315432", "type": "external" } ], "gene_names_uniprotkb": "sept4b; septin4b", "gene_names_refseq": "sept4b; septin4b", "protein_names_uniprotkb": "Septin", "protein_names_refseq": "septin 4b", "tax_id": 7955, "disease": "", "pathway": " (dre:100003446)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17967425;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505380 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001315432.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4Z5", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KQA6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KQY6-1", "uniprot_id": [ { "id": "S39AE_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KQY6", "type": "external" } ], "mass": 53266.0, "length": 494, "protein_name": "Metal cation symporter ZIP14", "gene_name": "slc39a14", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "slc39a14; ZIP-14; ZIP14; sb:cb823; zip14", "gene_names_refseq": "", "protein_names_uniprotkb": "Metal cation symporter ZIP14; Solute carrier family 39 member 14; ZIP-14; Zrt- and Irt-like protein 14", "protein_names_refseq": "", "tax_id": 7955, "disease": "hypermanganesemia with dystonia 2 (Disease Ontology:DOID:0080537)", "pathway": " (dre:799782); (R-DRE-442380)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;27231142", "class_list": "", "function": "Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron., [UniProtKB, PubMed]; Electroneutral transporter of the plasma membrane mediating the cellular uptake of the divalent metal cations zinc, manganese and iron that are important for tissue homeostasis, metabolism, development and immunity (PubMed:27231142). Functions as an energy-dependent symporter, transporting through the membranes an electroneutral complex composed of a divalent metal cation and two bicarbonate anions (By similarity). Beside these endogenous cellular substrates, can also import cadmium a non-essential metal which is cytotoxic and carcinogenic (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0005384 manganese ion transmembrane transporter activity;GO:0015086 cadmium ion transmembrane transporter activity;GO:0005381 iron ion transmembrane transporter activity;GO:0015296 monoatomic anion:monoatomic cation symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0006829 zinc ion transport;GO:0034755 iron ion transmembrane transport;GO:0098662 inorganic cation transmembrane transport;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KQY6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KR69-1", "uniprot_id": [ { "id": "A0A0G2KR69_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KR69", "type": "external" } ], "mass": 103863.0, "length": 990, "protein_name": "Embryonal Fyn-associated substrate", "gene_name": "efs", "organism": "Zebrafish", "refseq_name": "embryonal Fyn-associated substrate", "refseq_ac": [ { "id": "NP_001311337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001311337", "type": "external" } ], "gene_names_uniprotkb": "efs; fb77c11; wu:fb77c11", "gene_names_refseq": "efs; fb77c11; wu:fb77c11", "protein_names_uniprotkb": "Embryonal Fyn-associated substrate", "protein_names_refseq": "embryonal Fyn-associated substrate", "tax_id": 7955, "disease": "Crohn's disease (Disease Ontology:DOID:8778)", "pathway": " (dre:100333297)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;34903892", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01017534.1, SRR26395062.553041.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 4, 2016 this sequence version replaced XP_002662876.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P344", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007155 cell adhesion;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2KR69-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KRG9-1", "uniprot_id": [ { "id": "A0A0G2KRG9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KRG9", "type": "external" } ], "mass": 61098.0, "length": 533, "protein_name": "2.3.2.27; E3 ubiquitin-protein ligase TRIM39; Si:ch211-216p19.6", "gene_name": "si:ch211-216p19.6", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase TRIM39", "refseq_ac": [ { "id": "NP_001373742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373742", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-216p19.6", "gene_names_refseq": "si:ch211-216p19.6", "protein_names_uniprotkb": "2.3.2.27; E3 ubiquitin-protein ligase TRIM39; Si:ch211-216p19.6", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM39", "tax_id": 7955, "disease": "", "pathway": " (dre:100006636); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.13559084.1, SRR32588727.1399194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Sep 5, 2020 this sequence version replaced XP_005172385.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJQ3", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KRG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KRK2-1", "uniprot_id": [ { "id": "A0A0G2KRK2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KRK2", "type": "external" } ], "mass": 20586.0, "length": 179, "protein_name": "Gametocyte-specific factor 1", "gene_name": "LOC100535654", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100535654", "gene_names_refseq": "", "protein_names_uniprotkb": "Gametocyte-specific factor 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100535654)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z1U6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KRK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KRU2-1", "uniprot_id": [ { "id": "A0A0G2KRU2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KRU2", "type": "external" } ], "mass": 60073.0, "length": 530, "protein_name": "Lipoprotein lipase", "gene_name": "LOC101884800", "organism": "Zebrafish", "refseq_name": "lipoprotein lipase", "refseq_ac": [ { "id": "XP_005174466", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174466", "type": "external" } ], "gene_names_uniprotkb": "LOC101884800", "gene_names_refseq": "LOC101884800", "protein_names_uniprotkb": "Lipoprotein lipase; 3.1.1.34", "protein_names_refseq": "lipoprotein lipase", "tax_id": 7955, "disease": "", "pathway": " (dre:101884800)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLP2", "ec_number_list": [ { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0008201 heparin binding;GO:0034185 apolipoprotein binding;GO:0046872 metal ion binding;GO:0008970 phospholipase A1 activity;GO:0004465 lipoprotein lipase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0034375 high-density lipoprotein particle remodeling;GO:0042632 cholesterol homeostasis;GO:0019433 triglyceride catabolic process;GO:0034372 very-low-density lipoprotein particle remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KRU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KSF3-1", "uniprot_id": [ { "id": "A0A0G2KSF3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KSF3", "type": "external" } ], "mass": 38569.0, "length": 334, "protein_name": "Uncharacterized LOC103911589", "gene_name": "LOC103911589", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_009302657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302657", "type": "external" } ], "gene_names_uniprotkb": "LOC103911589", "gene_names_refseq": "LOC103911589", "protein_names_uniprotkb": "Uncharacterized LOC103911589", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:103911589)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B2D1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KSF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KT77-1", "uniprot_id": [ { "id": "A0A0G2KT77_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KT77", "type": "external" } ], "mass": 32859.0, "length": 302, "protein_name": "Chymotrypsinogen A; Serine protease 27-like", "gene_name": "LOC100004427", "organism": "Zebrafish", "refseq_name": "chymotrypsinogen A", "refseq_ac": [ { "id": "XP_005163955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163955", "type": "external" } ], "gene_names_uniprotkb": "LOC100004427", "gene_names_refseq": "LOC100004427", "protein_names_uniprotkb": "Chymotrypsinogen A; Serine protease 27-like", "protein_names_refseq": "chymotrypsinogen A", "tax_id": 7955, "disease": "", "pathway": " (dre:100004427)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BB59", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KT77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KT98-1", "uniprot_id": [ { "id": "A0A0G2KT98_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KT98", "type": "external" } ], "mass": 61625.0, "length": 527, "protein_name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1; Si:ch73-236c18.9", "gene_name": "si:ch73-236c18.9; zgc:174928", "organism": "Zebrafish", "refseq_name": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1", "refseq_ac": [ { "id": "XP_009294116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294116", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-236c18.9; zgc:174928; LOC793232; zgc:172007", "gene_names_refseq": "LOC793232", "protein_names_uniprotkb": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1; Si:ch73-236c18.9", "protein_names_refseq": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:792701); (dre:793232)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AXD7", "ec_number_list": [], "go_molecular_function": "GO:0008832 dGTPase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0051607 defense response to virus;GO:0006203 dGTP catabolic process;GO:0045088 regulation of innate immune response;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KT98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KTI4-1", "uniprot_id": [ { "id": "S12A2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KTI4", "type": "external" } ], "mass": 124112.0, "length": 1136, "protein_name": "Solute carrier family 12 member 2", "gene_name": "slc12a2", "organism": "Zebrafish", "refseq_name": "solute carrier family 12 member 2 isoform 1", "refseq_ac": [ { "id": "NP_001002080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002080", "type": "external" } ], "gene_names_uniprotkb": "slc12a2; BSC2; NKCC1; nkcc1; slc12a4; zgc:85961", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 12 member 2; BSC2; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; NKCC1; Na-K-Cl cotransporter 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "autosomal dominant nonsyndromic deafness 78 (Disease Ontology:DOID:0112159); sensorineural hearing loss (Disease Ontology:DOID:10003); hypertension (Disease Ontology:DOID:10763); epilepsy (Disease Ontology:DOID:1826); transient cerebral ischemia (Disease Ontology:DOID:224); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (dre:415170); (R-DRE-426117)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "19633174;23594743;31367042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC071283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC071283.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:31367042). Plays a vital role in the regulation of ionic balance and cell volume (PubMed:31367042). Important for maintenance of endolymph volume in the otic vesicle, probably by regulating ion homeostasis (PubMed:19633174). Also plays a role in normal development of the swim bladder (PubMed:19633174)., [UniProtKB, PubMed, PubMed]; Results show that zebrafish little ears (lte) mutations correspond to lesions in Nkcc1., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2KGS0;C7EA90;Q6IQW8", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0008519 ammonium channel activity;GO:0008511 sodium:potassium:chloride symporter activity;GO:0015377 chloride:monoatomic cation symporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0042472 inner ear morphogenesis;GO:0006884 cell volume homeostasis;GO:1902476 chloride transmembrane transport;GO:0035725 sodium ion transmembrane transport;GO:0055075 potassium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KTI4-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.0000000000000001.0000000011001.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KU24-1", "uniprot_id": [ { "id": "A0A0G2KU24_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KU24", "type": "external" } ], "mass": 39472.0, "length": 349, "protein_name": "Methyltransferase-like protein 24", "gene_name": "LOC101883617", "organism": "Zebrafish", "refseq_name": "probable methyltransferase-like protein 24", "refseq_ac": [ { "id": "XP_005159833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159833", "type": "external" } ], "gene_names_uniprotkb": "LOC101883617", "gene_names_refseq": "LOC101883617", "protein_names_uniprotkb": "Methyltransferase-like protein 24", "protein_names_refseq": "probable methyltransferase-like protein 24", "tax_id": 7955, "disease": "", "pathway": " (dre:101883617)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6N9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KU24-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KUB4-1", "uniprot_id": [ { "id": "A0A0G2KUB4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KUB4", "type": "external" } ], "mass": 41212.0, "length": 358, "protein_name": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein 995", "gene_name": "LOC103910762; si:dkey-22h13.1; znf995", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_009299025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299025", "type": "external" } ], "gene_names_uniprotkb": "LOC103910762; si:dkey-22h13.1; znf995; znf995", "gene_names_refseq": "LOC103910762", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein 995", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:103910762); (dre:108183708); (dre:563697)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_009299025.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B1Y7", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KUB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KUB6-1", "uniprot_id": [ { "id": "A0A0G2KUB6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KUB6", "type": "external" } ], "mass": 8850.0, "length": 76, "protein_name": "Uncharacterized protein LOC335475 precursor; Wu:fj16a03", "gene_name": "fj16a03", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC335475 precursor", "refseq_ac": [ { "id": "NP_001295483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295483", "type": "external" } ], "gene_names_uniprotkb": "fj16a03; wu:fj16a03", "gene_names_refseq": "fj16a03; wu:fj16a03", "protein_names_uniprotkb": "Uncharacterized protein LOC335475 precursor; Wu:fj16a03", "protein_names_refseq": "uncharacterized protein LOC335475 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:335475)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23559145;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH451757.1, EH530291.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1, EH533724.1 and EH442605.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6H2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KUB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KV12-1", "uniprot_id": [ { "id": "A0A0G2KV12_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KV12", "type": "external" } ], "mass": 41794.0, "length": 359, "protein_name": "Gastrula zinc finger protein XlCGF57.1-like; Gastrula zinc finger protein XlCGF8.2DB-like", "gene_name": "LOC108184006", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_017211284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211284", "type": "external" } ], "gene_names_uniprotkb": "LOC108184006", "gene_names_refseq": "LOC108184006", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1-like; Gastrula zinc finger protein XlCGF8.2DB-like", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:108184006)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YXV4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KV12-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KV16-1", "uniprot_id": [ { "id": "A0A0G2KV16_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KV16", "type": "external" } ], "mass": 120320.0, "length": 1038, "protein_name": "Interferon-induced protein with tetratricopeptide repeats 5", "gene_name": "LOC572297", "organism": "Zebrafish", "refseq_name": "interferon-induced protein with tetratricopeptide repeats 5", "refseq_ac": [ { "id": "NP_001289169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289169", "type": "external" } ], "gene_names_uniprotkb": "LOC572297; IFIT5A", "gene_names_refseq": "IFIT5A; LOC572297", "protein_names_uniprotkb": "Interferon-induced protein with tetratricopeptide repeats 5", "protein_names_refseq": "interferon-induced protein with tetratricopeptide repeats 5", "tax_id": 7955, "disease": "", "pathway": " (dre:572297)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;24950240", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01023943.1, SRR26395062.1311893.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Mar 4, 2017 this sequence version replaced XP_701096.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P612", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0051607 defense response to virus;GO:0042981 regulation of apoptotic process;GO:0051707 response to other organism", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KV16-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KWX9-1", "uniprot_id": [ { "id": "A0A0G2KWX9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KWX9", "type": "external" } ], "mass": 90944.0, "length": 824, "protein_name": "Low density lipoprotein receptor-related protein 3; Low-density lipoprotein receptor-related protein 3 precursor", "gene_name": "lrp3", "organism": "Zebrafish", "refseq_name": "low-density lipoprotein receptor-related protein 3 precursor", "refseq_ac": [ { "id": "NP_001124106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001124106", "type": "external" } ], "gene_names_uniprotkb": "lrp3; zgc:195027", "gene_names_refseq": "lrp3; zgc:195027", "protein_names_uniprotkb": "Low density lipoprotein receptor-related protein 3; Low-density lipoprotein receptor-related protein 3 precursor", "protein_names_refseq": "low-density lipoprotein receptor-related protein 3 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100170796)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;34338990", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC163507.1, SRR32588731.1397900.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476757, SAMEA4476762 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 21, 2024 this sequence version replaced NP_001124106.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B476", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2KWX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KWZ2-1", "uniprot_id": [ { "id": "A0A0G2KWZ2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KWZ2", "type": "external" } ], "mass": 12962.0, "length": 121, "protein_name": "C-X-C motif chemokine 11-6-like", "gene_name": "cxcl11.3", "organism": "Zebrafish", "refseq_name": "C-X-C motif chemokine 11-6-like", "refseq_ac": [ { "id": "XP_002662102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662102", "type": "external" } ], "gene_names_uniprotkb": "cxcl11.3; LOC100334604", "gene_names_refseq": "cxcl11.3", "protein_names_uniprotkb": "C-X-C motif chemokine 11-6-like", "protein_names_refseq": "C-X-C motif chemokine 11-6-like", "tax_id": 7955, "disease": "pulmonary sarcoidosis (Disease Ontology:DOID:13406); bronchiolitis obliterans (Disease Ontology:DOID:2799); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (dre:100334604)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002662102.2. COMPLETENESS: full length., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDH8", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006952 defense response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KWZ2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KXF2-1", "uniprot_id": [ { "id": "A0A0G2KXF2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KXF2", "type": "external" } ], "mass": 61300.0, "length": 541, "protein_name": "Zinc finger protein 513", "gene_name": "znf513b", "organism": "Zebrafish", "refseq_name": "zinc finger protein 513", "refseq_ac": [ { "id": "XP_697406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697406", "type": "external" } ], "gene_names_uniprotkb": "znf513b; LOC568955", "gene_names_refseq": "znf513b", "protein_names_uniprotkb": "Zinc finger protein 513", "protein_names_refseq": "zinc finger protein 513", "tax_id": 7955, "disease": "", "pathway": " (dre:568955)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_697406.3. COMPLETENESS: full length., [RefSeq]; Transcriptional regulator that plays a role in retinal development and maintenance., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVL3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KXF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KXF6-1", "uniprot_id": [ { "id": "A0A0G2KXF6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KXF6", "type": "external" } ], "mass": 42749.0, "length": 385, "protein_name": "Aristaless-related homeobox b; Aristaless-related homeobox protein", "gene_name": "arxb", "organism": "Zebrafish", "refseq_name": "aristaless-related homeobox protein", "refseq_ac": [ { "id": "XP_002667096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667096", "type": "external" } ], "gene_names_uniprotkb": "arxb", "gene_names_refseq": "arxb", "protein_names_uniprotkb": "Aristaless-related homeobox b; Aristaless-related homeobox protein", "protein_names_refseq": "aristaless-related homeobox protein", "tax_id": 7955, "disease": "lissencephaly (Disease Ontology:DOID:0050453); early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); syndromic X-linked intellectual disability Hedera type (Disease Ontology:DOID:0060806); developmental and epileptic encephalopathy 1 (Disease Ontology:DOID:0080468); non-syndromic X-linked intellectual disability ARX-related (Disease Ontology:DOID:0112021); corpus callosum agenesis-abnormal genitalia syndrome (Disease Ontology:DOID:0112151); X-linked lissencephaly 2 (Disease Ontology:DOID:0112238); Partington syndrome (Disease Ontology:DOID:14744)", "pathway": " (dre:100329907)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1REJ1", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KXF6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KYC0-1", "uniprot_id": [ { "id": "A0A0G2KYC0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KYC0", "type": "external" } ], "mass": 80263.0, "length": 726, "protein_name": "Cytoplasmic polyadenylation element-binding protein 4b", "gene_name": "cpeb4b", "organism": "Zebrafish", "refseq_name": "cytoplasmic polyadenylation element-binding protein 4b", "refseq_ac": [ { "id": "NP_001338642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338642", "type": "external" } ], "gene_names_uniprotkb": "cpeb4b", "gene_names_refseq": "cpeb4b", "protein_names_uniprotkb": "Cytoplasmic polyadenylation element-binding protein 4b", "protein_names_refseq": "cytoplasmic polyadenylation element binding protein 4-like; cytoplasmic polyadenylation element-binding protein 4b", "tax_id": 7955, "disease": "portal hypertension (Disease Ontology:DOID:10762); primary biliary cholangitis (Disease Ontology:DOID:12236); liver cirrhosis (Disease Ontology:DOID:5082)", "pathway": " (dre:100333151)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01018658.1, SRR32588728.3642639.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1, EH436310.1, EH454853.1, EH435528.1, EH580807.1 and EH455067.1. On May 23, 2017 this sequence version replaced XP_009293951.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PAR7", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0008135 translation factor activity, RNA binding;GO:0043022 ribosome binding;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045202 synapse;GO:0043005 neuron projection", "go_biological_process": "GO:2000766 negative regulation of cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KYC0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KYH9-1", "uniprot_id": [ { "id": "A0A0G2KYH9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KYH9", "type": "external" } ], "mass": 11002.0, "length": 98, "protein_name": "Chemokine (C-X-C motif) ligand 8a; Interleukin-8 isoform X1", "gene_name": "cxcl8a", "organism": "Zebrafish", "refseq_name": "growth-regulated alpha protein isoform X1", "refseq_ac": [ { "id": "XP_001342606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001342606", "type": "external" } ], "gene_names_uniprotkb": "cxcl8a", "gene_names_refseq": "cxcl8a", "protein_names_uniprotkb": "Chemokine (C-X-C motif) ligand 8a; Interleukin-8 isoform X1", "protein_names_refseq": "growth-regulated alpha protein isoform X1", "tax_id": 7955, "disease": "autoimmune uveitis (Disease Ontology:DOID:0040088); chikungunya (Disease Ontology:DOID:0050012); extrapulmonary tuberculosis (Disease Ontology:DOID:0050598); COVID-19 (Disease Ontology:DOID:0080600); urinary tract infection (Disease Ontology:DOID:0080784); acute asthma (Disease Ontology:DOID:0080810); vitamin D-dependent rickets (Disease Ontology:DOID:0080883); trypanosomiasis (Disease Ontology:DOID:10113); leprosy (Disease Ontology:DOID:1024); common cold (Disease Ontology:DOID:10459); brucellosis (Disease Ontology:DOID:11077); trachoma (Disease Ontology:DOID:11265); adult respiratory distress syndrome (Disease Ontology:DOID:11394); primary biliary cholangitis (Disease Ontology:DOID:12236); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); eumycotic mycetoma (Disease Ontology:DOID:13078); biliary atresia (Disease Ontology:DOID:13608); cystic fibrosis (Disease Ontology:DOID:1485); intrahepatic cholestasis (Disease Ontology:DOID:1852); hepatitis C (Disease Ontology:DOID:1883); vulvovaginal candidiasis (Disease Ontology:DOID:2272); multiple sclerosis (Disease Ontology:DOID:2377); Mycobacterium avium complex disease (Disease Ontology:DOID:2755); endometriosis (Disease Ontology:DOID:289); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); pulmonary fibrosis (Disease Ontology:DOID:3770); tuberculosis (Disease Ontology:DOID:399); gastritis (Disease Ontology:DOID:4029); bacterial gastritis (Disease Ontology:DOID:4033); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); stomach carcinoma (Disease Ontology:DOID:5517); acute pyelonephritis (Disease Ontology:DOID:559); viral encephalitis (Disease Ontology:DOID:646); hepatocellular carcinoma (Disease Ontology:DOID:684); visceral leishmaniasis (Disease Ontology:DOID:9146)", "pathway": " (dre:100002946); (R-DRE-114608); (R-DRE-380108); (R-DRE-418594); (R-DRE-6798695)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001342606.1. COMPLETENESS: full length., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 39, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q7Q0", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity;GO:0045236 CXCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001525 angiogenesis;GO:0001570 vasculogenesis;GO:0006954 inflammatory response;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0060218 hematopoietic stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KYH9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KYR2-1", "uniprot_id": [ { "id": "A0A0G2KYR2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KYR2", "type": "external" } ], "mass": 56998.0, "length": 501, "protein_name": "Lymphocyte specific protein 1 b isoform 1; Lymphocyte-specific protein 1 b", "gene_name": "lsp1b", "organism": "Zebrafish", "refseq_name": "lymphocyte specific protein 1 b isoform 1", "refseq_ac": [ { "id": "NP_001410761", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410761", "type": "external" } ], "gene_names_uniprotkb": "lsp1b; si: ch211-223l2.4; si:ch211-223l2.4", "gene_names_refseq": "lsp1b; si: ch211-223l2.4; si:ch211-223l2.4", "protein_names_uniprotkb": "Lymphocyte specific protein 1 b isoform 1; Lymphocyte-specific protein 1 b", "protein_names_refseq": "caldesmon, smooth muscle-like; lymphocyte specific protein 1 b isoform 1", "tax_id": 7955, "disease": "breast cancer (Disease Ontology:DOID:1612)", "pathway": " (dre:100002400)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;29180615", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.1689772.1, SRR26395014.329489.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 16, 2023 this sequence version replaced XP_001338671.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PZ90", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0017022 myosin binding", "go_cellular_component": "", "go_biological_process": "GO:0006936 muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KYR2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KZ26-1", "uniprot_id": [ { "id": "A0A0G2KZ26_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KZ26", "type": "external" } ], "mass": 30690.0, "length": 277, "protein_name": "Single-strand-selective monofunctional uracil-DNA glycosylase 1", "gene_name": "smug1", "organism": "Zebrafish", "refseq_name": "single-strand selective monofunctional uracil DNA glycosylase", "refseq_ac": [ { "id": "NP_001373273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373273", "type": "external" } ], "gene_names_uniprotkb": "smug1; fj81c12; wu:fj81c12", "gene_names_refseq": "LOC570901", "protein_names_uniprotkb": "Single-strand-selective monofunctional uracil-DNA glycosylase 1", "protein_names_refseq": "single-strand selective monofunctional uracil DNA glycosylase", "tax_id": 7955, "disease": "", "pathway": " (dre:570901); (R-DRE-110329); (R-DRE-110357)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505371, SAMEA4476752 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Aug 21, 2020 this sequence version replaced XP_017213755.1. Sequence Note:., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z3B3", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0004844 uracil DNA N-glycosylase activity;GO:0017065 single-strand selective uracil DNA N-glycosylase activity;GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2KZ26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KZN8-1", "uniprot_id": [ { "id": "A0A0G2KZN8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2KZN8", "type": "external" } ], "mass": 31766.0, "length": 276, "protein_name": "Gastrula zinc finger protein XlCGF8.2DB-like", "gene_name": "LOC100007471", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_021326585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326585", "type": "external" } ], "gene_names_uniprotkb": "LOC100007471", "gene_names_refseq": "LOC100007471", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF8.2DB-like", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:100007471)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PZP7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KZN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L033-1", "uniprot_id": [ { "id": "A0A0G2L033_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L033", "type": "external" } ], "mass": 42895.0, "length": 380, "protein_name": "Organic solute carrier partner 1b; Protein OSCP1", "gene_name": "oscp1b", "organism": "Zebrafish", "refseq_name": "protein OSCP1", "refseq_ac": [ { "id": "XP_002667777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667777", "type": "external" } ], "gene_names_uniprotkb": "oscp1b", "gene_names_refseq": "oscp1b", "protein_names_uniprotkb": "Organic solute carrier partner 1b; Protein OSCP1", "protein_names_refseq": "protein OSCP1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334608)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1REP6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L033-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L0E2-1", "uniprot_id": [ { "id": "A0A0G2L0E2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L0E2", "type": "external" } ], "mass": 53238.0, "length": 466, "protein_name": "Zinc-binding protein A33", "gene_name": "LOC100536643", "organism": "Zebrafish", "refseq_name": "zinc-binding protein A33 isoform X1", "refseq_ac": [ { "id": "XP_003198215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198215", "type": "external" } ], "gene_names_uniprotkb": "LOC100536643", "gene_names_refseq": "LOC100536643", "protein_names_uniprotkb": "Zinc-binding protein A33", "protein_names_refseq": "zinc-binding protein A33 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100536643)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003198215.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RNB8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L0E2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L0J2-1", "uniprot_id": [ { "id": "A0A0G2L0J2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L0J2", "type": "external" } ], "mass": 22901.0, "length": 199, "protein_name": "5-formyltetrahydrofolate cyclo-ligase", "gene_name": "mthfs", "organism": "Zebrafish", "refseq_name": "5-formyltetrahydrofolate cyclo-ligase", "refseq_ac": [ { "id": "NP_001373342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373342", "type": "external" } ], "gene_names_uniprotkb": "mthfs", "gene_names_refseq": "mthfs", "protein_names_uniprotkb": "5-formyltetrahydrofolate cyclo-ligase; 6.3.3.2", "protein_names_refseq": "5-formyltetrahydrofolate cyclo-ligase", "tax_id": 7955, "disease": "", "pathway": " (dre:100332843); (R-DRE-196757)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01017407.1, GDQH01022239.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505380, SAMEA4476736 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 21, 2020 this sequence version replaced XP_002662791.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z7S3", "ec_number_list": [ { "id": "6.3.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.3.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0009396 folic acid-containing compound biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L0J2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L0Q2-1", "uniprot_id": [ { "id": "A0A0G2L0Q2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L0Q2", "type": "external" } ], "mass": 28394.0, "length": 242, "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "gene_name": "hacd1", "organism": "Zebrafish", "refseq_name": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "refseq_ac": [ { "id": "NP_001314793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314793", "type": "external" } ], "gene_names_uniprotkb": "hacd1; ptpla", "gene_names_refseq": "hacd1; ptpla", "protein_names_uniprotkb": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; 4.2.1.134", "protein_names_refseq": "protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A; protein tyrosine phosphatase-like, member A; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "tax_id": 7955, "disease": "congenital myopathy (Disease Ontology:DOID:0081337)", "pathway": " (dre:553326); (R-DRE-75876)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "12477932;21873635;23594743;34016526", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH591206.1, EL646435.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 27, 2016 this sequence version replaced XP_699783.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9G1", "ec_number_list": [ { "id": "4.2.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.134", "type": "external" } ], "go_molecular_function": "GO:0018812 3-hydroxyacyl-CoA dehydratase activity;GO:0102158 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0030497 fatty acid elongation;GO:0042761 very long-chain fatty acid biosynthetic process;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2L0Q2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L0R2-1", "uniprot_id": [ { "id": "A0A0G2L0R2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L0R2", "type": "external" } ], "mass": 36740.0, "length": 333, "protein_name": "G-protein coupled receptor 6", "gene_name": "gpr6", "organism": "Zebrafish", "refseq_name": "G-protein coupled receptor 6", "refseq_ac": [ { "id": "XP_003200829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200829", "type": "external" } ], "gene_names_uniprotkb": "gpr6", "gene_names_refseq": "gpr6", "protein_names_uniprotkb": "G-protein coupled receptor 6", "protein_names_refseq": "G-protein coupled receptor 6", "tax_id": 7955, "disease": "", "pathway": " (dre:100538060)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;33801713", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8E7UDD7", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L0R2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L199-1", "uniprot_id": [ { "id": "A0A0G2L199_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L199", "type": "external" } ], "mass": 37686.0, "length": 326, "protein_name": "Si:cabz01069013.3; Uncharacterized protein LOC796738", "gene_name": "si:cabz01069013.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC796738", "refseq_ac": [ { "id": "NP_001314850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314850", "type": "external" } ], "gene_names_uniprotkb": "si:cabz01069013.3; si:cabz01069013", "gene_names_refseq": "si:cabz01069013.3; si:cabz01069013", "protein_names_uniprotkb": "Si:cabz01069013.3; Uncharacterized protein LOC796738", "protein_names_refseq": "uncharacterized protein LOC796738", "tax_id": 7955, "disease": "", "pathway": " (dre:796738)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588725.44886358.1, SRR32588731.1649134.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350655 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On or before Jul 30, 2025 this sequence version replaced XP_073802813.1, NP_001314850.2. Sequence Note:., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2L601;A0A8M1P9K1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L199-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L1F4-1", "uniprot_id": [ { "id": "A0A0G2L1F4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L1F4", "type": "external" } ], "mass": 17861.0, "length": 157, "protein_name": "Dr1-associated corepressor", "gene_name": "LOC100535468", "organism": "Zebrafish", "refseq_name": "dr1-associated corepressor isoform X1", "refseq_ac": [ { "id": "XP_003200419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200419", "type": "external" } ], "gene_names_uniprotkb": "LOC100535468", "gene_names_refseq": "LOC100535468", "protein_names_uniprotkb": "Dr1-associated corepressor; Dr1-associated protein 1; Negative cofactor 2-alpha", "protein_names_refseq": "dr1-associated corepressor isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100535468)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200419.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFI4", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0001046 core promoter sequence-specific DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017054 negative cofactor 2 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L1F4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L1H9-1", "uniprot_id": [ { "id": "A0A0G2L1H9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L1H9", "type": "external" } ], "mass": 22139.0, "length": 198, "protein_name": "Sperm-associated antigen 8", "gene_name": "spag8", "organism": "Zebrafish", "refseq_name": "sperm-associated antigen 8", "refseq_ac": [ { "id": "NP_001373667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373667", "type": "external" } ], "gene_names_uniprotkb": "spag8", "gene_names_refseq": "spag8", "protein_names_uniprotkb": "Sperm-associated antigen 8", "protein_names_refseq": "sperm-associated antigen 8", "tax_id": 7955, "disease": "", "pathway": " (dre:571789)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;29051429", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01000383.1, GDQH01035143.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505380 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and BC154807.1. On Jun 13, 2025 this sequence version replaced NP_001373667.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFK2", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2L1H9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L264-1", "uniprot_id": [ { "id": "A0A0G2L264_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L264", "type": "external" } ], "mass": 22146.0, "length": 195, "protein_name": "Ras-related protein Rab-35", "gene_name": "rab35a", "organism": "Zebrafish", "refseq_name": "ras-related protein Rab-35", "refseq_ac": [ { "id": "NP_001373674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373674", "type": "external" } ], "gene_names_uniprotkb": "rab35a; rab35", "gene_names_refseq": "rab35a; rab35", "protein_names_uniprotkb": "Ras-related protein Rab-35; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-35", "tax_id": 7955, "disease": "", "pathway": " (dre:796454)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;25556858;28396820;37186603", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH511180.1, EH484739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Sep 3, 2020 this sequence version replaced XP_001334079.5., [RefSeq]; Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PRX4", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0042470 melanosome;GO:0010008 endosome membrane;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2L264-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L2I4-1", "uniprot_id": [ { "id": "A0A0G2L2I4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L2I4", "type": "external" } ], "mass": 10569.0, "length": 93, "protein_name": "C-C motif chemokine", "gene_name": "ccl36.1", "organism": "Zebrafish", "refseq_name": "C-C motif chemokine 36.1 precursor", "refseq_ac": [ { "id": "NP_001373675", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373675", "type": "external" } ], "gene_names_uniprotkb": "ccl36.1; CCL-CUi; CCL-chr7a; CCL36ab", "gene_names_refseq": "CCL-CUi; CCL-chr7a; CCL36ab; ccl36.1", "protein_names_uniprotkb": "C-C motif chemokine", "protein_names_refseq": "C-C motif chemokine 36.1 precursor; chemokine CCL-CUi", "tax_id": 7955, "disease": "", "pathway": " (dre:100537088); (R-DRE-380108); (R-DRE-416476); (R-DRE-418594); (R-DRE-444473)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "16365434;18482437;23145839;23594743;29760055;32605167", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01016940.1, EH487952.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Aug 8, 2023 this sequence version replaced NP_001108569.1, XP_003199028.1., [RefSeq]; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RSN7", "ec_number_list": [], "go_molecular_function": "GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0G2L2I4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L2I7-1", "uniprot_id": [ { "id": "A0A0G2L2I7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L2I7", "type": "external" } ], "mass": 73877.0, "length": 669, "protein_name": "C2 calcium-dependent domain-containing 2; C2 domain-containing protein 2 isoform X1", "gene_name": "c2cd2", "organism": "Zebrafish", "refseq_name": "C2 domain-containing protein 2 isoform X1", "refseq_ac": [ { "id": "XP_009303774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303774", "type": "external" } ], "gene_names_uniprotkb": "c2cd2", "gene_names_refseq": "c2cd2", "protein_names_uniprotkb": "C2 calcium-dependent domain-containing 2; C2 domain-containing protein 2 isoform X1", "protein_names_refseq": "C2 domain-containing protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100332559)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BD78", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L2I7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L2K4-1", "uniprot_id": [ { "id": "A0A0G2L2K4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L2K4", "type": "external" } ], "mass": 45729.0, "length": 410, "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7d", "organism": "Zebrafish", "refseq_name": "5-hydroxytryptamine receptor 7", "refseq_ac": [ { "id": "XP_003199632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199632", "type": "external" } ], "gene_names_uniprotkb": "htr7d; htr7", "gene_names_refseq": "htr7", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 7; Serotonin receptor 7", "protein_names_refseq": "5-hydroxytryptamine receptor 7", "tax_id": 7955, "disease": "", "pathway": " (dre:100536080)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003199632.1. COMPLETENESS: full length., [RefSeq]; G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RIZ1", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0004938 alpha2-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L2K4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L2Q2-1", "uniprot_id": [ { "id": "A0A0G2L2Q2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L2Q2", "type": "external" } ], "mass": 7222.0, "length": 62, "protein_name": "Complex III subunit 9", "gene_name": "uqcr10", "organism": "Zebrafish", "refseq_name": "cytochrome b-c1 complex subunit 9", "refseq_ac": [ { "id": "NP_001289407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289407", "type": "external" } ], "gene_names_uniprotkb": "uqcr10", "gene_names_refseq": "uqcr10", "protein_names_uniprotkb": "Complex III subunit 9", "protein_names_refseq": "TCONS_00052125; cytochrome b-c1 complex subunit 9", "tax_id": 7955, "disease": "", "pathway": " (dre:100333064); (R-DRE-611105); (R-DRE-9865881)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "23594743;28252024;28455512;33548715;34141984;36317480", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH435283.1, EH503399.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH435283.1 and EH490607.1. On Oct 22, 2014 this sequence version replaced XP_003200865.1., [RefSeq]; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6L2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0G2L2Q2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L2X0-1", "uniprot_id": [ { "id": "A0A0G2L2X0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L2X0", "type": "external" } ], "mass": 40474.0, "length": 354, "protein_name": "Gastrula zinc finger protein XlCGF8.2DB-like; Zinc finger protein OZF", "gene_name": "LOC110437819", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_021324630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324630", "type": "external" } ], "gene_names_uniprotkb": "LOC110437819", "gene_names_refseq": "LOC110437819", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF8.2DB-like; Zinc finger protein OZF", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:110437819)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PU81", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0032502 developmental process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L2X0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L2X8-1", "uniprot_id": [ { "id": "A0A0G2L2X8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L2X8", "type": "external" } ], "mass": 19844.0, "length": 167, "protein_name": "Expressed sequence EH456644; UPF0686 protein C11orf1 homolog", "gene_name": "cfap68", "organism": "Zebrafish", "refseq_name": "cilia- and flagella-associated protein 68", "refseq_ac": [ { "id": "NP_001313533", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313533", "type": "external" } ], "gene_names_uniprotkb": "cfap68; c5h11orf1; gb:eh456644", "gene_names_refseq": "c5h11orf1; cfap68; gb:eh456644", "protein_names_uniprotkb": "Expressed sequence EH456644; UPF0686 protein C11orf1 homolog", "protein_names_refseq": "UPF0686 protein C11orf1 homolog; cilia- and flagella-associated protein 68", "tax_id": 7955, "disease": "", "pathway": " (dre:797203)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025100.1, EB836158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1, EH455520.1 and EH482375.1. On May 21, 2016 this sequence version replaced XP_001334782.3., [RefSeq]; Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2V3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005930 axoneme", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L2X8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L3K9-1", "uniprot_id": [ { "id": "A0A0G2L3K9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L3K9", "type": "external" } ], "mass": 55611.0, "length": 483, "protein_name": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein 431", "gene_name": "LOC101886047", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_005171139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171139", "type": "external" } ], "gene_names_uniprotkb": "LOC101886047", "gene_names_refseq": "LOC101886047", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1-like; Zinc finger protein 431", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:101886047)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BIC8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L3K9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L4D1-1", "uniprot_id": [ { "id": "A0A0G2L4D1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L4D1", "type": "external" } ], "mass": 29514.0, "length": 277, "protein_name": "Aquaporin-14; Aquaporin-4", "gene_name": "LOC101885864", "organism": "Zebrafish", "refseq_name": "aquaporin-4", "refseq_ac": [ { "id": "XP_005174182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174182", "type": "external" } ], "gene_names_uniprotkb": "LOC101885864; Aqp14", "gene_names_refseq": "LOC101885864", "protein_names_uniprotkb": "Aquaporin-14; Aquaporin-4", "protein_names_refseq": "aquaporin-4", "tax_id": 7955, "disease": "", "pathway": " (dre:101885864)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;31840107", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A6B9KBC7", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006833 water transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L4D1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L4S8-1", "uniprot_id": [ { "id": "A0A0G2L4S8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L4S8", "type": "external" } ], "mass": 34589.0, "length": 315, "protein_name": "Aerolysin-like protein; Jacalin 3", "gene_name": "jac3", "organism": "Zebrafish", "refseq_name": "aerolysin-like protein isoform X1", "refseq_ac": [ { "id": "XP_001920106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920106", "type": "external" } ], "gene_names_uniprotkb": "jac3", "gene_names_refseq": "jac3", "protein_names_uniprotkb": "Aerolysin-like protein; Jacalin 3", "protein_names_refseq": "aerolysin-like protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:797839)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QKE2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L4S8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L4V3-1", "uniprot_id": [ { "id": "A0A0G2L4V3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L4V3", "type": "external" } ], "mass": 49859.0, "length": 444, "protein_name": "SH3 domain-binding protein 5", "gene_name": "sh3bp5a", "organism": "Zebrafish", "refseq_name": "SH3 domain-binding protein 5", "refseq_ac": [ { "id": "XP_682769", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_682769", "type": "external" } ], "gene_names_uniprotkb": "sh3bp5a", "gene_names_refseq": "sh3bp5a", "protein_names_uniprotkb": "SH3 domain-binding protein 5; SH3BP-5", "protein_names_refseq": "SH3 domain-binding protein 5", "tax_id": 7955, "disease": "", "pathway": " (dre:555222)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_682769.4. COMPLETENESS: full length., [RefSeq]; Functions as guanine nucleotide exchange factor (GEF) for RAB11A., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVJ1", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0004860 protein kinase inhibitor activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L4V3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L574-1", "uniprot_id": [ { "id": "A0A0G2L574_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L574", "type": "external" } ], "mass": 50082.0, "length": 452, "protein_name": "SLAM family member 5; Uncharacterized LOC100538136", "gene_name": "LOC100538136", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_009294245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294245", "type": "external" } ], "gene_names_uniprotkb": "LOC100538136", "gene_names_refseq": "LOC100538136", "protein_names_uniprotkb": "SLAM family member 5; Uncharacterized LOC100538136", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:100538136)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AXG1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L574-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L648-1", "uniprot_id": [ { "id": "A0A0G2L648_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L648", "type": "external" } ], "mass": 39265.0, "length": 348, "protein_name": "PHD finger protein 13", "gene_name": "phf13", "organism": "Zebrafish", "refseq_name": "PHD finger protein 13", "refseq_ac": [ { "id": "XP_003201700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201700", "type": "external" } ], "gene_names_uniprotkb": "phf13", "gene_names_refseq": "phf13", "protein_names_uniprotkb": "PHD finger protein 13", "protein_names_refseq": "PHD finger protein 13", "tax_id": 7955, "disease": "", "pathway": " (dre:100537300)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Modulates chromatin structure and DNA damage response by regulating key determinants of chromatin compaction and DNA damage response. Binds H3K4me3-containing chromatin and promotes DNA condensation by recruiting corepressors such as TRIM28 and H3K9 methyltransferase SETDB1. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis. Increases both chromatin-associated levels and activity of H3K9 methyltransferases, such as SETDB1, thus enhancing H3K9 trimethylation. Essential for testicular stem-cell differentiation and sustained spermatogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RTN3", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0051301 cell division;GO:0007076 mitotic chromosome condensation;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L648-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L677-1", "uniprot_id": [ { "id": "A0A0G2L677_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L677", "type": "external" } ], "mass": 7438.0, "length": 65, "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "mrpl33", "organism": "Zebrafish", "refseq_name": "large ribosomal subunit protein bL33m", "refseq_ac": [ { "id": "NP_001290051", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290051", "type": "external" } ], "gene_names_uniprotkb": "mrpl33; im:6911600", "gene_names_refseq": "im:6911600; mrpl33", "protein_names_uniprotkb": "Large ribosomal subunit protein bL33m; 39S ribosomal protein L33, mitochondrial", "protein_names_refseq": "large ribosomal subunit protein bL33m", "tax_id": 7955, "disease": "", "pathway": " (dre:100536515); (R-DRE-5389840); (R-DRE-5419276); (R-DRE-9937383)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "21873635;23594743;36077499", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH557056.1, EH490154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH557056.1 and EH465531.1. On Dec 17, 2014 this sequence version replaced XP_003200410.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the protein., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P663", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2L677-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L6W9-1", "uniprot_id": [ { "id": "A0A0G2L6W9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L6W9", "type": "external" } ], "mass": 7434.0, "length": 68, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "gng10", "organism": "Zebrafish", "refseq_name": "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "refseq_ac": [ { "id": "NP_001191955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191955", "type": "external" } ], "gene_names_uniprotkb": "gng10", "gene_names_refseq": "gng10", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "G protein subunit gamma 10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "tax_id": 7955, "disease": "", "pathway": " (dre:796780); (R-DRE-202040); (R-DRE-381676); (R-DRE-392170); (R-DRE-400042); (R-DRE-416476); (R-DRE-418594); (R-DRE-418597); (R-DRE-420092); (R-DRE-428930); (R-DRE-432040); (R-DRE-456926); (R-DRE-9856530)", "pathway_count": 13, "publication_count": 3, "publication_id_list": "19786091;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011697.1, EH571040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Apr 16, 2011 this sequence version replaced XP_001923216.1., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1V0", "ec_number_list": [], "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2L6W9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L765-1", "uniprot_id": [ { "id": "A0A0G2L765_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L765", "type": "external" } ], "mass": 7211.0, "length": 62, "protein_name": "Uncharacterized LOC797202; Uncharacterized protein LOC797202", "gene_name": "LOC797202", "organism": "Zebrafish", "refseq_name": "salivary gland specific protein SAGSIN1", "refseq_ac": [ { "id": "NP_001156915", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156915", "type": "external" } ], "gene_names_uniprotkb": "LOC797202", "gene_names_refseq": "smim10l3", "protein_names_uniprotkb": "Uncharacterized LOC797202; Uncharacterized protein LOC797202", "protein_names_refseq": "salivary gland specific protein SAGSIN1", "tax_id": 7955, "disease": "", "pathway": " (dre:797202)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122141.1, BI846208.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA4476760 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122141.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NRY1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L765-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L7C5-1", "uniprot_id": [ { "id": "A0A0G2L7C5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L7C5", "type": "external" } ], "mass": 281682.0, "length": 2384, "protein_name": "Leucine-rich repeat-containing protein DDB_G0290503; Si:dkey-185m8.2", "gene_name": "si:dkey-185m8.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-185m8.2", "refseq_ac": [ { "id": "XP_005166414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166414", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-185m8.2", "gene_names_refseq": "si:dkey-185m8.2", "protein_names_uniprotkb": "Leucine-rich repeat-containing protein DDB_G0290503; Si:dkey-185m8.2", "protein_names_refseq": "uncharacterized protein si:dkey-185m8.2", "tax_id": 7955, "disease": "", "pathway": " (dre:101885702)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDU5", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L7C5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L7I0-1", "uniprot_id": [ { "id": "SPRTN_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L7I0", "type": "external" } ], "mass": 70224.0, "length": 636, "protein_name": "DNA-dependent metalloprotease SPRTN", "gene_name": "sprtn", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "sprtn", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA-dependent metalloprotease SPRTN; 3.4.24.-; Protein with SprT-like domain at the N terminus; Spartan", "protein_names_refseq": "", "tax_id": 7955, "disease": "Ruijs-Aalfs syndrome (Disease Ontology:DOID:0111264)", "pathway": " (dre:101886162); (R-DRE-110320)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "23594743;25261934;33514542;37788708", "class_list": "", "function": "DNA-dependent metalloendopeptidase that mediates the proteolytic cleavage of covalent DNA-protein cross-links (DPCs) during DNA synthesis, thereby playing a key role in maintaining genomic integrity. DPCs are highly toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription, and which are induced by reactive agents, such as UV light or formaldehyde. Associates with the DNA replication machinery and specifically removes DPCs during DNA synthesis. Catalyzes proteolytic cleavage of the hmces DNA-protein cross-link following unfolding by the brip1/fancj helicase. Acts as a pleiotropic protease for DNA-binding proteins cross-linked with DNA, such as top1, top2a, histones H3 and H4. Mediates degradation of DPCs that are not ubiquitinated, while it is not able to degrade ubiquitinated DPCs. SPRTN activation requires polymerase collision with DPCs followed by helicase bypass of DPCs. May also act as a 'reader' of ubiquitinated pcna: facilitates chromatin association of rad18 and is required for efficient pcna monoubiquitination, promoting a feed-forward loop to enhance pcna ubiquitination and translesion DNA synthesis. Acts as a regulator of translesion DNA synthesis by recruiting vcp/p97 to sites of DNA damage., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" } ], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005694 chromosome", "go_biological_process": "GO:0006508 proteolysis;GO:0006974 DNA damage response;GO:0016540 protein autoprocessing;GO:0106300 protein-DNA covalent cross-linking repair;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2L7I0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L7P5-1", "uniprot_id": [ { "id": "A0A0G2L7P5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L7P5", "type": "external" } ], "mass": 14060.0, "length": 127, "protein_name": "Heterogeneous nuclear ribonucleoprotein A1-like", "gene_name": "LOC101883902", "organism": "Zebrafish", "refseq_name": "heterogeneous nuclear ribonucleoprotein A1-like 3", "refseq_ac": [ { "id": "XP_005171710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171710", "type": "external" } ], "gene_names_uniprotkb": "LOC101883902", "gene_names_refseq": "LOC101883902", "protein_names_uniprotkb": "Heterogeneous nuclear ribonucleoprotein A1-like", "protein_names_refseq": "heterogeneous nuclear ribonucleoprotein A1-like 3", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_005171710.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJ01", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005681 spliceosomal complex", "go_biological_process": "GO:0048026 positive regulation of mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L7P5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L866-1", "uniprot_id": [ { "id": "A0A0G2L866_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L866", "type": "external" } ], "mass": 89418.0, "length": 793, "protein_name": "Inactive dipeptidyl peptidase 10 isoform X1; Inactive dipeptidyl peptidase 10-like", "gene_name": "LOC101886435", "organism": "Zebrafish", "refseq_name": "inactive dipeptidyl peptidase 10 isoform X1", "refseq_ac": [ { "id": "XP_009295302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295302", "type": "external" } ], "gene_names_uniprotkb": "LOC101886435", "gene_names_refseq": "LOC101886435", "protein_names_uniprotkb": "Inactive dipeptidyl peptidase 10 isoform X1; Inactive dipeptidyl peptidase 10-like", "protein_names_refseq": "inactive dipeptidyl peptidase 10 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101886435)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AVM3", "ec_number_list": [], "go_molecular_function": "GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L866-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L8H6-1", "uniprot_id": [ { "id": "A0A0G2L8H6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L8H6", "type": "external" } ], "mass": 45008.0, "length": 392, "protein_name": "Gastrula zinc finger protein XlCGF8.2DB-like; Uncharacterized protein LOC100150619", "gene_name": "LOC100150619", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100150619", "refseq_ac": [ { "id": "NP_001314928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314928", "type": "external" } ], "gene_names_uniprotkb": "LOC100150619", "gene_names_refseq": "LOC100150619", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF8.2DB-like; Uncharacterized protein LOC100150619", "protein_names_refseq": "uncharacterized protein LOC100150619", "tax_id": 7955, "disease": "", "pathway": " (dre:100150619)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC159216.1, SRR26395012.1610342.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476771, SAMEA4476779 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jun 2, 2016 this sequence version replaced XP_001923943.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P460", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L8H6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L9C2-1", "uniprot_id": [ { "id": "A0A0G2L9C2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L9C2", "type": "external" } ], "mass": 24247.0, "length": 215, "protein_name": "Lysosomal protein transmembrane 5; Mtp family protein", "gene_name": "laptm5", "organism": "Zebrafish", "refseq_name": "Mtp family protein", "refseq_ac": [ { "id": "NP_001155999", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155999", "type": "external" } ], "gene_names_uniprotkb": "laptm5; LOC100151049", "gene_names_refseq": "laptm5", "protein_names_uniprotkb": "Lysosomal protein transmembrane 5; Mtp family protein", "protein_names_refseq": "Mtp family protein", "tax_id": 7955, "disease": "", "pathway": " (dre:100151049)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH483628.1 and EH467735.1. On Jun 27, 2009 this sequence version replaced XP_001923185.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUW5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2L9C2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2L9Z2-1", "uniprot_id": [ { "id": "A0A0G2L9Z2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2L9Z2", "type": "external" } ], "mass": 34924.0, "length": 307, "protein_name": "Leucine-rich repeat-containing protein 30", "gene_name": "lrrc30b", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_003198027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198027", "type": "external" } ], "gene_names_uniprotkb": "lrrc30b; LOC100534875", "gene_names_refseq": "LOC100534875", "protein_names_uniprotkb": "Leucine-rich repeat-containing protein 30", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003198027.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RN87", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2L9Z2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2LAE2-1", "uniprot_id": [ { "id": "A0A0G2LAE2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2LAE2", "type": "external" } ], "mass": 39624.0, "length": 334, "protein_name": "Zinc finger protein 239-like", "gene_name": "LOC100148620", "organism": "Zebrafish", "refseq_name": "zinc finger protein 239-like isoform 1", "refseq_ac": [ { "id": "NP_001373196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373196", "type": "external" } ], "gene_names_uniprotkb": "LOC100148620", "gene_names_refseq": "LOC100148620", "protein_names_uniprotkb": "Zinc finger protein 239-like", "protein_names_refseq": "zinc finger protein 239-like isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:100148620)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01015828.1, CK698711.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001373196.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QQV2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2LAE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2LAF7-1", "uniprot_id": [ { "id": "A0A0G2LAF7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2LAF7", "type": "external" } ], "mass": 39243.0, "length": 358, "protein_name": "Si:ch73-170d6.3", "gene_name": "si:ch73-170d6.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-170d6.3", "refseq_ac": [ { "id": "XP_002662199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662199", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-170d6.3", "gene_names_refseq": "si:ch73-170d6.3", "protein_names_uniprotkb": "Si:ch73-170d6.3", "protein_names_refseq": "uncharacterized protein si:ch73-170d6.3", "tax_id": 7955, "disease": "", "pathway": " (dre:100334140)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_002662199.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDI0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2LAF7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2LAJ1-1", "uniprot_id": [ { "id": "A0A0G2LAJ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2LAJ1", "type": "external" } ], "mass": 62198.0, "length": 540, "protein_name": "Tripartite motif-containing protein 16", "gene_name": "LOC100006839", "organism": "Zebrafish", "refseq_name": "tripartite motif-containing protein 16 isoform X2", "refseq_ac": [ { "id": "XP_002666648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002666648", "type": "external" } ], "gene_names_uniprotkb": "LOC100006839", "gene_names_refseq": "LOC100006839", "protein_names_uniprotkb": "Tripartite motif-containing protein 16", "protein_names_refseq": "tripartite motif-containing protein 16 isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:100006839); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RRY0", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2LAJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2LAJ5-1", "uniprot_id": [ { "id": "A0A0G2LAJ5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2LAJ5", "type": "external" } ], "mass": 135527.0, "length": 1189, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "atp8b5b", "organism": "Zebrafish", "refseq_name": "phospholipid-transporting ATPase ID", "refseq_ac": [ { "id": "XP_691903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691903", "type": "external" } ], "gene_names_uniprotkb": "atp8b5b", "gene_names_refseq": "atp8b5b", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "phospholipid-transporting ATPase ID", "tax_id": 7955, "disease": "", "pathway": " (dre:563450)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_691903.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7T2", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity;GO:0140345 phosphatidylcholine flippase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2LAJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2LAU9-1", "uniprot_id": [ { "id": "A0A0G2LAU9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0G2LAU9", "type": "external" } ], "mass": 41005.0, "length": 355, "protein_name": "Guanine nucleotide binding protein (G protein), alpha z polypeptide; Guanine nucleotide-binding protein G(Z) subunit alpha", "gene_name": "gnaz", "organism": "Zebrafish", "refseq_name": "guanine nucleotide-binding protein G(z) subunit alpha", "refseq_ac": [ { "id": "XP_005155690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155690", "type": "external" } ], "gene_names_uniprotkb": "gnaz", "gene_names_refseq": "gnaz", "protein_names_uniprotkb": "Guanine nucleotide binding protein (G protein), alpha z polypeptide; Guanine nucleotide-binding protein G(Z) subunit alpha", "protein_names_refseq": "guanine nucleotide-binding protein G(z) subunit alpha", "tax_id": 7955, "disease": "", "pathway": " (dre:564915); (R-DRE-418597)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_005155690.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B1R3", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2LAU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2LB96-1", "uniprot_id": [ { "id": "A0A0G2LB96_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0G2LB96", "type": "external" } ], "mass": 13078.0, "length": 114, "protein_name": "T cell receptor beta variable 29", "gene_name": "Trbv29", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Trbv29; Trbv28", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor beta variable 29", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "21606376;21750661;35999236", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2LB96-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC03-1", "uniprot_id": [ { "id": "A0A0G2QC03_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC03", "type": "external" } ], "mass": 71509.0, "length": 642, "protein_name": "Influenza virus NS1A binding protein", "gene_name": "Ivns1abp", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ivns1abp", "gene_names_refseq": "", "protein_names_uniprotkb": "Influenza virus NS1A binding protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "immunodeficiency 70 (Disease Ontology:DOID:0112005)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", 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"external" } ], "gene_names_uniprotkb": "Pls1", "gene_names_refseq": "Pls1", "protein_names_uniprotkb": "Plastin 1", "protein_names_refseq": "plastin-1", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 76 (Disease Ontology:DOID:0112167); Huntington's disease (Disease Ontology:DOID:12858)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, 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protein localization to plasma membrane;GO:0051639 actin filament network formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2QC04-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC08-1", "uniprot_id": [ { "id": "A0A0G2QC08_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC08", "type": "external" } ], "mass": 31370.0, "length": 296, "protein_name": "C1q and TNF related 7", "gene_name": "C1qtnf7", "organism": "Rat", "refseq_name": "complement C1q tumor necrosis factor-related protein 7 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001423759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423759", "type": "external" } ], "gene_names_uniprotkb": "C1qtnf7", "gene_names_refseq": "Adig; C1qtnf7; Ctrp7", "protein_names_uniprotkb": "C1q and TNF related 7", "protein_names_refseq": "C1q and tumor necrosis factor related protein 7; adiponectin g; complement C1q tumor necrosis factor-related protein 7 isoform 2 precursor; complement C1q tumor necrosis factor-related protein 7", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "17716811;36514218", "class_list": "", "function": "Deletion of large-conductance calcium-activated potassium channels promotes vascular remodelling through the CTRP7-mediated PI3K/Akt signaling pathway., [RefSeq, PubMed]; The purpose of the current study was to investigate age-dependent effects of caloric restriction on the release of adiponectin, expression and activation of adiponectin-related signaling and on parameters of altered insulin sensitivity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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space;GO:0005581 collagen trimer", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2QC08-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC13-1", "uniprot_id": [ { "id": "A0A0G2QC13_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC13", "type": "external" } ], "mass": 57751.0, "length": 497, "protein_name": "Zinc finger protein 709-like 1", "gene_name": "Zfp709l1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp709l1; LOC100912823; Zfp790l3", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 709-like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2QC13-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC19-1", "uniprot_id": [ { "id": "A0A0G2QC19_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC19", "type": "external" } ], "mass": 70812.0, "length": 613, "protein_name": "DnaJ homolog subfamily C member 21", "gene_name": "Dnajc21", "organism": "Rat", "refseq_name": "dnaJ homolog subfamily C member 21", "refseq_ac": [ { "id": "NP_620211", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620211", "type": "external" } ], "gene_names_uniprotkb": "Dnajc21", "gene_names_refseq": "Dnaja5; Dnajc21", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 21", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily C, member 21; DnaJ homology subfamily A member 5; dnaJ homolog subfamily C member 21; putative regulation protein GS3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S rRNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2QC19-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC22-1", "uniprot_id": [ { "id": "A0A0G2QC22_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC22", "type": "external" } ], "mass": 24239.0, "length": 225, "protein_name": "PAXX, non-homologous end joining factor", "gene_name": "Paxx", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Paxx; RGD1306215", "gene_names_refseq": "", "protein_names_uniprotkb": "PAXX, non-homologous end joining factor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042803 protein homodimerization activity;GO:0070182 DNA polymerase binding", "go_cellular_component": "GO:0070419 nonhomologous end joining complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0035861 site of double-strand break;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2QC22-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC27-1", "uniprot_id": [ { "id": "A0A0G2QC27_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC27", "type": "external" } ], "mass": 128069.0, "length": 1146, "protein_name": "Nucleolar protein 6", "gene_name": "Nol6", "organism": "Rat", "refseq_name": "nucleolar protein 6", "refseq_ac": [ { "id": "NP_001414130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414130", "type": "external" } ], "gene_names_uniprotkb": "Nol6", "gene_names_refseq": "Nol6", "protein_names_uniprotkb": "Nucleolar protein 6", "protein_names_refseq": "nucleolar protein 6 (RNA-associated); nucleolar protein 6; nucleolar protein family 6 (RNA-associated)", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6791226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005730 nucleolus;GO:0032040 small-subunit processome;GO:0032545 CURI complex;GO:0034456 UTP-C complex", "go_biological_process": "GO:0042274 ribosomal small subunit biogenesis;GO:0006409 tRNA export from nucleus;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2QC27-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC33-1", "uniprot_id": [ { "id": "ATG4B_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC33", "type": "external" } ], "mass": 44364.0, "length": 393, "protein_name": "Cysteine protease ATG4B", "gene_name": "Atg4b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Atg4b", "gene_names_refseq": "", "protein_names_uniprotkb": "Cysteine protease ATG4B; 3.4.22.-; Autophagy-related protein 4 homolog B", "protein_names_refseq": "", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (R-RNO-1632852)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;28633005", "class_list": "", "function": "Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3. In addition to the protease activity, also mediates delipidation of ATG8 family proteins. Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy. Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, by catalyzing delipidation of ATG8 proteins conjugated to phosphatidylserine (PS). Compared to other members of the family (ATG4A, ATG4C or ATG4C), constitutes the major protein for proteolytic activation of ATG8 proteins, while it displays weaker delipidation activity than other ATG4 paralogs. Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, 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transferase", "gene_name": "Mkrn1", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase makorin-1 isoform 1", "refseq_ac": [ { "id": "NP_001385662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385662", "type": "external" } ], "gene_names_uniprotkb": "Mkrn1", "gene_names_refseq": "Mkrn1", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27; RING-type E3 ubiquitin transferase makorin-1", "protein_names_refseq": "E3 ubiquitin-protein ligase makorin-1 isoform 1; E3 ubiquitin-protein ligase makorin-1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-198323); (R-RNO-8948751); (R-RNO-983168)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "22128154;33647316", "class_list": "", "function": "Identification of MKRN1 as a second E3 ligase for Eag1 potassium channels reveals regulation via differential degradation., [RefSeq, PubMed]; In mammalian neurons MKRN1-short interacts with PABP to locally control the translation of dendritic mRNAs at synapses., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "", "go_biological_process": "GO:1990830 cellular response to leukemia inhibitory factor;GO:0000209 protein polyubiquitination;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2QC40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC43-1", "uniprot_id": [ { "id": "A0A0G2QC43_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC43", "type": "external" } ], "mass": 29922.0, "length": 260, "protein_name": "Regulator of G-protein signaling like 2 homolog (mouse)", "gene_name": "Rgsl2h", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rgsl2h", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulator of G-protein signaling like 2 homolog (mouse)", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2QC43-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC52-1", "uniprot_id": [ { "id": "A0A0G2QC52_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "type": "external" } ], "mass": 28558.0, "length": 250, "protein_name": "RAB, member of RAS oncogene family like 2", "gene_name": "Rabl2", "organism": "Rat", "refseq_name": "rab-like protein 2B isoform X1", "refseq_ac": [ { "id": "XP_006242287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006242287", "type": "external" } ], "gene_names_uniprotkb": "Rabl2; Rabl2a", "gene_names_refseq": "Rabl2a; Rabl2b; Rabl2", "protein_names_uniprotkb": "RAB, member of RAS oncogene family like 2", "protein_names_refseq": "rab-like protein 2B isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, 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"type": "external" } ], "mass": 28445.0, "length": 263, "protein_name": "TPD52 like 3", "gene_name": "Tpd52l3", "organism": "Rat", "refseq_name": "tumor protein D55 isoform 2", "refseq_ac": [ { "id": "NP_001424473", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424473", "type": "external" } ], "gene_names_uniprotkb": "Tpd52l3", "gene_names_refseq": "RGD1309391; Tpd52l3; Trpd52l3", "protein_names_uniprotkb": "TPD52 like 3", "protein_names_refseq": "tumor protein D52-like 3; tumor protein D55 isoform 2; tumor protein D55-like; tumor protein D55", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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"hit_score": 0.2, "record_id": "A0A0G2QC54-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC55-1", "uniprot_id": [ { "id": "A0A0G2QC55_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55", "type": "external" } ], "mass": 32697.0, "length": 292, "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "Tssk4", "organism": "Rat", "refseq_name": "testis-specific serine/threonine-protein kinase 4 isoform 1", "refseq_ac": [ { "id": "NP_001258254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258254", "type": "external" } ], "gene_names_uniprotkb": "Tssk4", "gene_names_refseq": "RGD1560814; Tssk4", "protein_names_uniprotkb": "Testis-specific serine/threonine-protein kinase 4; 2.7.11.1", "protein_names_refseq": "testis-specific serine/threonine-protein kinase 4 isoform 1; testis-specific serine/threonine-protein kinase 4", "tax_id": 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May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. 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"Vomeronasal type-1 receptor", "protein_names_refseq": "vomeronasal type-1 receptor 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100738814)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 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"https://www.uniprot.org/uniprot/A0A0G3Y3D1", "type": "external" } ], "mass": 80153.0, "length": 742, "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "slco4a1", "organism": "Zebrafish", "refseq_name": "solute carrier organic anion transporter family member 4A1", "refseq_ac": [ { "id": "NP_001297061", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297061", "type": "external" } ], "gene_names_uniprotkb": "slco4a1", "gene_names_refseq": "slco4a1", "protein_names_uniprotkb": "Solute carrier organic anion transporter family member", "protein_names_refseq": "Oatp4a1; solute carrier anion transporting family member 4a1; solute carrier organic anion transporter family member 4A1; zOatp4a2", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-879518)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "16648940;19931635;23594743;24113777;25253178;26055554;26469318;27189481;28143724", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KP294322.1, KP294323.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KP294323.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015347 sodium-independent organic anion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0043252 sodium-independent organic anion transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0G3Y3D1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H2UHJ3-1", "uniprot_id": [ { "id": "A0A0H2UHJ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0H2UHJ3", "type": "external" } ], "mass": 11561.0, "length": 113, "protein_name": "Large ribosomal subunit protein P1", "gene_name": "Rplp1l1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rplp1l1; RGD1564744", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein P1; 60S acidic ribosomal protein P1", "protein_names_refseq": "", "tax_id": 10116, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (rno:314652)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the elongation step of protein synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:0030295 protein kinase activator activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006417 regulation of translation;GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0H2UHJ3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H2UHL4-1", "uniprot_id": [ { "id": "A0A0H2UHL4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0H2UHL4", "type": "external" } ], "mass": 37061.0, "length": 331, "protein_name": "MAS related GPR family member X3", "gene_name": "Mrgprx3", "organism": "Rat", "refseq_name": "mas-related G-protein coupled receptor member A", "refseq_ac": [ { "id": "NP_665730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_665730", "type": "external" } ], "gene_names_uniprotkb": "Mrgprx3", "gene_names_refseq": "Mgrg1; MrgA; Mrga10; Mrgpra; Mrgprx3", "protein_names_uniprotkb": "MAS related GPR family member X3", "protein_names_refseq": "G-protein coupled receptor; MAS-related G-protein coupled receptor, member A; MAS-related GPR, member X3; Mas-related G protein-coupled receptor g1; Mas-related gene A; adenine receptor; mas-related G-protein coupled receptor member A; nuclear receptor MrgA10 RF-amide G protein-coupled receptor; rc 56.1.3", "tax_id": 10116, "disease": "", "pathway": " (rno:252960)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15604413;17728165;35770633", "class_list": "", "function": "Kinetics of adenine binding to the adenine receptor of the rat brain cortex., [RefSeq, PubMed]; Results validate the predicted structure for MrgA and should be useful for seeking other small molecule agonists and antagonists., [RefSeq, PubMed]; [The distribution of Mas-related G protein-coupled receptor A in cerebrospinal fluid-contacting nucleus of normal rats and its up-regulation in neuropathic pain]., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005525 GTP binding;GO:0008188 neuropeptide receptor activity;GO:0031409 pigment binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:1905237 response to cyclosporin A;GO:1901652 response to peptide;GO:0160025 sensory perception of itch", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0H2UHL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H2UI11-1", "uniprot_id": [ { "id": "A0A0H2UI11_RAT", "url": "https://www.uniprot.org/uniprot/A0A0H2UI11", "type": "external" } ], "mass": 6254.0, "length": 51, "protein_name": "Uncharacterized protein", "gene_name": "Rpl39l2", "organism": "Rat", "refseq_name": "large ribosomal subunit protein eL39-like", "refseq_ac": [ { "id": "XP_038956522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038956522", "type": "external" } ], "gene_names_uniprotkb": "Rpl39l2; LOC103690889", "gene_names_refseq": "Rpl39l2", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "large ribosomal subunit protein eL39-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0H2UI11-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H2UJB2-1", "uniprot_id": [ { "id": "A0A0H2UJB2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0H2UJB2", "type": "external" } ], "mass": 102179.0, "length": 926, "protein_name": "Protein inturned", "gene_name": "intu", "organism": "Zebrafish", "refseq_name": "protein inturned", "refseq_ac": [ { "id": "NP_001340861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001340861", "type": "external" } ], "gene_names_uniprotkb": "intu", "gene_names_refseq": "intu", "protein_names_uniprotkb": "Protein inturned; Inturned planar cell polarity effector homolog", "protein_names_refseq": "inturned planar cell polarity effector homolog; protein inturned", "tax_id": 7955, "disease": "asphyxiating thoracic dystrophy (Disease Ontology:DOID:0050592); orofaciodigital syndrome XVII (Disease Ontology:DOID:0080289)", "pathway": " (dre:100007575)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01021186.1, GFIL01013445.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jul 29, 2017 this sequence version replaced XP_001345998.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0009986 cell surface", "go_biological_process": "GO:0060271 cilium assembly;GO:0016192 vesicle-mediated transport;GO:0001736 establishment of planar polarity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0H2UJB2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H2UKU4-1", "uniprot_id": [ { "id": "A0A0H2UKU4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0H2UKU4", "type": "external" } ], "mass": 135934.0, "length": 1242, "protein_name": "Protocadherin-7b", "gene_name": "pcdh7b", "organism": "Zebrafish", "refseq_name": "protocadherin-7b", "refseq_ac": [ { "id": "NP_001352582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352582", "type": "external" } ], "gene_names_uniprotkb": "pcdh7b; sb:eu592; si:dkey-104n16.1", "gene_names_refseq": "pcdh7b; sb:eu592; si:dkey-104n16.1", "protein_names_uniprotkb": "Protocadherin-7b", "protein_names_refseq": "novel protocadherin protein; protocadherin 7; protocadherin-7b", "tax_id": 7955, "disease": "", "pathway": " (dre:555504); (R-DRE-114608); (R-DRE-8980692); (R-DRE-9013026)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "22001682;23457027;23594743;25931248;26469318;27189481;29576475;34650032;35514229;36936789;37272628", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01029662.1, SRR32588727.2566978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Sep 12, 2018 this sequence version replaced XP_683121.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TCQ2", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0H2UKU4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H2UKW6-1", "uniprot_id": [ { "id": "A0A0H2UKW6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0H2UKW6", "type": "external" } ], "mass": 69465.0, "length": 645, "protein_name": "A kinase (PRKA) anchor protein 8-like; A-kinase anchor protein 8-like", "gene_name": "akap8l", "organism": "Zebrafish", "refseq_name": "A-kinase anchor protein 8-like", "refseq_ac": [ { "id": "NP_998384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998384", "type": "external" } ], "gene_names_uniprotkb": "akap8l; wu:fc52f04; wu:fe38d08; wu:fm58f09; zgc:85966", "gene_names_refseq": "akap8l; wu:fc52f04; wu:fe38d08; wu:fm58f09; zgc:85966", "protein_names_uniprotkb": "A kinase (PRKA) anchor protein 8-like; A-kinase anchor protein 8-like", "protein_names_refseq": "A-kinase anchor protein 8-like", "tax_id": 7955, "disease": "", "pathway": " (dre:406500)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16109975;23594743;25503746;27189481;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC068435.1, SRR26395014.1398863.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On May 17, 2016 this sequence version replaced NP_998384.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PET4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007076 mitotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0H2UKW6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H5ANC0-1", "uniprot_id": [ { "id": "A0A0H5ANC0_PIG", "url": "https://www.uniprot.org/uniprot/A0A0H5ANC0", "type": "external" } ], "mass": 33986.0, "length": 298, "protein_name": "Mimecan", "gene_name": "OGN", "organism": "Pig", "refseq_name": "mimecan precursor", "refseq_ac": [ { "id": "NP_001302657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001302657", "type": "external" } ], "gene_names_uniprotkb": "OGN", "gene_names_refseq": "OGN", "protein_names_uniprotkb": "Mimecan; Osteoglycin", "protein_names_refseq": "mimecan precursor; osteoglycin/mimecan", "tax_id": 9823, "disease": "", "pathway": " (ssc:106509723); (R-SSC-2022854); (R-SSC-2022857)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16879361;28958189", "class_list": "", "function": "Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2., [UniProtKB, UniProtKB]; Mapping of the OGN and ASPN genes and association with growth and carcass traits., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TYW8", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0060348 bone development;GO:0061975 articular cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0H5ANC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0H5AX08-1", "uniprot_id": [ { "id": "A0A0H5AX08_PIG", "url": "https://www.uniprot.org/uniprot/A0A0H5AX08", "type": "external" } ], "mass": 61904.0, "length": 534, "protein_name": "CARD9; Caspase recruitment domain family member 9; Caspase recruitment domain family, member 9", "gene_name": "CARD9", "organism": "Pig", "refseq_name": "caspase recruitment domain-containing protein 9 isoform X5", "refseq_ac": [ { "id": "XP_020936810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936810", "type": "external" } ], "gene_names_uniprotkb": "CARD9", "gene_names_refseq": "CARD9", "protein_names_uniprotkb": "CARD9; Caspase recruitment domain family member 9; Caspase recruitment domain family, member 9", "protein_names_refseq": "caspase recruitment domain-containing protein 9 isoform X5", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5607764)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BEN6", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0035591 signaling adaptor activity;GO:0050700 CARD domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032449 CBM complex", "go_biological_process": "GO:0032740 positive regulation of interleukin-17 production;GO:0046330 positive regulation of JNK cascade;GO:0050830 defense response to Gram-positive bacterium;GO:0051260 protein homooligomerization;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0H5AX08-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0J9YJ57-1", "uniprot_id": [ { "id": "A0A0J9YJ57_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0J9YJ57", "type": "external" } ], "mass": 99615.0, "length": 880, "protein_name": "PPFIA-binding protein 1a; Uncharacterized protein isoform X1", "gene_name": "ppfibp1a", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_005164718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164718", "type": "external" } ], "gene_names_uniprotkb": "ppfibp1a; si:dkey-207j16.2", "gene_names_refseq": "ppfibp1a; si:dkey-207j16.2", "protein_names_uniprotkb": "PPFIA-binding protein 1a; Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:565020)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;25601102;25630924;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBT4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0048786 presynaptic active zone", "go_biological_process": "GO:0007528 neuromuscular junction development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0J9YJ57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0J9YJ98-1", "uniprot_id": [ { "id": "A0A0J9YJ98_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0J9YJ98", "type": "external" } ], "mass": 10810.0, "length": 99, "protein_name": "Essential MCU regulator, mitochondrial", "gene_name": "smdt1b", "organism": "Zebrafish", "refseq_name": "single-pass membrane protein with aspartate-rich tail 1b", "refseq_ac": [ { "id": "NP_001313451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313451", "type": "external" } ], "gene_names_uniprotkb": "smdt1b; si:ch211-133l11.4", "gene_names_refseq": "si:ch211-133l11.4; smdt1b", "protein_names_uniprotkb": "Essential MCU regulator, mitochondrial; Single-pass membrane protein with aspartate-rich tail 1, mitochondrial", "protein_names_refseq": "single-pass membrane protein with aspartate-rich tail 1b", "tax_id": 7955, "disease": "", "pathway": " (dre:100000862); (R-DRE-8949215); (R-DRE-8949664); (R-DRE-9837999)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH505644.1, EH566783.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505379 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH545643.1 and EH505644.1. On May 20, 2016 this sequence version replaced XP_001340971.1., [RefSeq]; Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A075B6M6;A0A0A6YYM7;A0A5A0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0K0K1E9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0K0K1G6-1", "uniprot_id": [ { "id": "TVBJ3_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0K0K1G6", "type": "external" } ], "mass": 13035.0, "length": 114, "protein_name": "T cell receptor beta variable 10-3", "gene_name": "TRBV10-3", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV10-3", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor beta variable 10-3", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A087WV87;A0A5A5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0K0K1G6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0K0K1G8-1", "uniprot_id": [ { "id": "TVBJ2_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0K0K1G8", "type": "external" } ], "mass": 13045.0, "length": 114, "protein_name": "T cell receptor beta variable 10-2", "gene_name": "TRBV10-2", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV10-2", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor beta variable 10-2", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The reference sequence was derived from KT023307.1. On Aug 4, 2015 this sequence version replaced XP_009293151.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1U2", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0031708 endothelin B receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045987 positive regulation of smooth muscle contraction;GO:0006874 intracellular calcium ion homeostasis;GO:0019229 regulation of vasoconstriction;GO:0003100 regulation of systemic arterial blood pressure by endothelin;GO:0014826 vein smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0K0WSQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0K1H345-1", "uniprot_id": [ { "id": "A0A0K1H345_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0K1H345", "type": "external" } ], "mass": 16267.0, "length": 141, "protein_name": "NK-lysin tandem duplicate 2; Nk-lysin", "gene_name": "nkl.2", "organism": "Zebrafish", "refseq_name": "NK-lysin tandem duplicate 2 precursor", "refseq_ac": [ { "id": "NP_001298721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001298721", "type": "external" } ], "gene_names_uniprotkb": "nkl.2; Nk-lysin; nklb", "gene_names_refseq": "Nk-lysin; nkl.2; nklb", "protein_names_uniprotkb": "NK-lysin tandem duplicate 2; Nk-lysin", "protein_names_refseq": "NK-lysin tandem duplicate 2 precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "23594743;25813149;28087841;28878000;31001250;35588359;36995466", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KP100116.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. 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The reference sequence was derived from KP100115.1. On Aug 12, 2015 this sequence version replaced XP_009291115.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0K1H367-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0K1SB73-1", "uniprot_id": [ { "id": "A0A0K1SB73_PIG", "url": "https://www.uniprot.org/uniprot/A0A0K1SB73", "type": "external" } ], "mass": 100361.0, "length": 911, "protein_name": "Inner nuclear membrane protein Man1", "gene_name": "LEMD3", "organism": "Pig", "refseq_name": "inner nuclear membrane protein Man1", "refseq_ac": [ { "id": "NP_001302526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001302526", "type": "external" } ], "gene_names_uniprotkb": "LEMD3", "gene_names_refseq": "LEMD3", "protein_names_uniprotkb": "Inner nuclear membrane protein Man1; LEM domain-containing protein 3", "protein_names_refseq": "inner nuclear membrane protein Man1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511508)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "25006967;30587124;30723633", "class_list": "", "function": "Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Genome-wide analysis combined with linkage results revealed LEMD3 and WIF1 as the candidates for porcine ear size. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0030514 negative regulation of BMP signaling pathway;GO:0032926 negative regulation of activin receptor signaling pathway;GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006998 nuclear envelope organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0K1SB73-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000010000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0K2S4Q6-1", "uniprot_id": [ { "id": "CD3CH_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0K2S4Q6", "type": "external" } ], "mass": 21806.0, "length": 201, "protein_name": "Protein CD300H", "gene_name": "CD300H", "organism": "Human", "refseq_name": "protein CD300H isoform 1 precursor", "refseq_ac": [ { "id": "NP_001311002", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001311002", "type": "external" } ], "gene_names_uniprotkb": "CD300H", "gene_names_refseq": "CD300Hs; CD300H", "protein_names_uniprotkb": "Protein CD300H; CD300 antigen-like family member H", "protein_names_refseq": "CD300 antigen-like family member H; CD300c molecule-like; protein CD300H isoform 1 precursor; protein CD300H", "tax_id": 9606, "disease": "", "pathway": " (hsa:100130520)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26221034", "class_list": "", "function": "May play an important role in innate immunity by mediating a signal for the production of a neutrophil chemoattractant., [UniProtKB, PubMed]; Results suggest that CD300H may play an important role in innate immunity., [RefSeq, PubMed]; This gene belongs to the CD300 gene family, which in turn, belongs to the immunoglobulin (Ig) superfamily. This gene is located within a CD300 cluster on chromosome 17. The encoded protein may be involved in innate immunity as well as autoimmune response. A G>A mutation, represented by the single nucleotide polymorphism (SNP) rs905709, at the splice donor site of the 5' terminal exon may be associated with lack of expression of this gene in homozygous (AA) individuals. The human reference assembly (GRCh38.p2) represents the 'A' allele at this SNP. [provided by RefSeq, Apr 2016]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 3, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0K2S5L2;A0A286YF48", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0045088 regulation of innate immune response;GO:0030593 neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0K2S4Q6-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M3HER8-1", "uniprot_id": [ { "id": "A0A0M3HER8_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0M3HER8", "type": "external" } ], "mass": 62799.0, "length": 536, "protein_name": "Golgin A6 family like 10", "gene_name": "GOLGA6L10", "organism": "Human", "refseq_name": "golgin subfamily A member 6-like protein 10 isoform 2", "refseq_ac": [ { "id": "NP_001309329", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309329", "type": "external" } ], "gene_names_uniprotkb": "GOLGA6L10", "gene_names_refseq": "GOLGA6L10; GOLGA6L18", "protein_names_uniprotkb": "Golgin A6 family like 10", "protein_names_refseq": "golgi autoantigen, golgin subfamily a, 6-like 10; golgin A6 family-like 18; golgin subfamily A member 6-like protein 10 isoform 2; putative golgin subfamily A member 6-like protein 10", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0M3HER8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M3KL53-1", "uniprot_id": [ { "id": "A0A0M3KL53_PIG", "url": "https://www.uniprot.org/uniprot/A0A0M3KL53", "type": "external" } ], "mass": 15092.0, "length": 128, "protein_name": "28S ribosomal protein S14, mitochondrial", "gene_name": "MRPS14", "organism": "Pig", "refseq_name": "28S ribosomal protein S14, mitochondrial", "refseq_ac": [ { "id": "XP_013845079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845079", "type": "external" } ], "gene_names_uniprotkb": "MRPS14", "gene_names_refseq": "MRPS14", "protein_names_uniprotkb": "28S ribosomal protein S14, mitochondrial", "protein_names_refseq": "28S ribosomal protein S14, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "25837512;30089917;30723633;32602580;33878294;37141370", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UDB0", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0031965 nuclear membrane;GO:0005737 cytoplasm;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0M3KL53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M3KL54-1", "uniprot_id": [ { "id": "A0A0M3KL54_PIG", "url": "https://www.uniprot.org/uniprot/A0A0M3KL54", "type": "external" } ], "mass": 16185.0, "length": 143, "protein_name": "Small ribosomal subunit protein bS18m", "gene_name": "MRPS18C", "organism": "Pig", "refseq_name": "28S ribosomal protein S18c, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_003129404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129404", "type": "external" } ], "gene_names_uniprotkb": "MRPS18C", "gene_names_refseq": "MRPS18C", "protein_names_uniprotkb": "Small ribosomal subunit protein bS18m; 28S ribosomal protein S18-1, mitochondrial; 28S ribosomal protein S18c, mitochondrial", "protein_names_refseq": "28S ribosomal protein S18c, mitochondrial isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "25837512;30089917;30723633;32602580;33878294;37141370", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AA83", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0070181 small ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0M3KL54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M3KL55-1", "uniprot_id": [ { "id": "A0A0M3KL55_PIG", "url": "https://www.uniprot.org/uniprot/A0A0M3KL55", "type": "external" } ], "mass": 19924.0, "length": 173, "protein_name": "Small ribosomal subunit protein mS25", "gene_name": "MRPS25", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MRPS25", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein mS25; 28S ribosomal protein S25, mitochondrial", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "25837512;30089917;30723633;32602580;33878294;37141370", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0M3KL55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M3KL56-1", "uniprot_id": [ { "id": "A0A0M3KL56_PIG", "url": "https://www.uniprot.org/uniprot/A0A0M3KL56", "type": "external" } ], "mass": 20979.0, "length": 188, "protein_name": "28S ribosomal protein S28, mitochondrial; Mitochondrial ribosomal protein S28; Mitoribosomal protein ms28, mrps28", "gene_name": "MRPS28", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MRPS28", "gene_names_refseq": "", "protein_names_uniprotkb": "28S ribosomal protein S28, mitochondrial; Mitochondrial ribosomal protein S28; Mitoribosomal protein ms28, mrps28", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "25837512;30089917;30723633;32602580;33878294;37141370", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UDQ5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0M3KL56-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M3U1B0-1", "uniprot_id": [ { "id": "SYC2L_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0M3U1B0", "type": "external" } ], "mass": 96055.0, "length": 842, "protein_name": "Synaptonemal complex protein 2-like", "gene_name": "Sycp2l", "organism": "Mouse", "refseq_name": "synaptonemal complex protein 2-like", "refseq_ac": [ { "id": "NP_001311454", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001311454", "type": "external" } ], "gene_names_uniprotkb": "Sycp2l", "gene_names_refseq": "EG621792; Gm268; Gm40956; Sycp2l", "protein_names_uniprotkb": "Synaptonemal complex protein 2-like; SCP-2-like", "protein_names_refseq": "SCP-2-like; synaptonemal complex protein 2-like", "tax_id": 10090, "disease": "", "pathway": " (mmu:637277)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21750661;26362258", "class_list": "", "function": "Oocyte-specific protein that localizes to centromeres at the dictyate stage and regulates the survival of primordial oocytes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3YWV8;F6RWL8;F6ZC70", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000779 condensed chromosome, centromeric region;GO:0000800 lateral element;GO:0001674 female germ cell nucleus", "go_biological_process": "GO:0043069 negative regulation of programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0M3U1B0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M6L0J6-1", "uniprot_id": [ { "id": "A0A0M6L0J6_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0M6L0J6", "type": "external" } ], "mass": 25532.0, "length": 224, "protein_name": "Growth hormone d6; Prolactin family 3, subfamily d, member 3", "gene_name": "Prl3d3", "organism": "Mouse", "refseq_name": "prolactin family 3, subfamily d, member 3 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001348026", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001348026", "type": "external" } ], "gene_names_uniprotkb": "Prl3d3; Ghd6; Plig", "gene_names_refseq": "Ghd6; PL-Ig; Plig; Prl3d3", "protein_names_uniprotkb": "Growth hormone d6; Prolactin family 3, subfamily d, member 3", "protein_names_refseq": "PL-1 gamma; growth hormone d6; placental lactogen I gamma; prolactin family 3, subfamily d, member 3 isoform 2 precursor", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "12488360;21750661;23963683;26697363;26862561", "class_list": "", "function": "Results show that endogenous levels of Pkig reciprocally regulate osteoblast and adipocyte differentiation and that this reciprocal regulation is mediated in part by LIF., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005148 prolactin receptor binding;GO:0046872 metal ion binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0031667 response to nutrient levels;GO:0007565 female pregnancy;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0030879 mammary gland development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0M6L0J6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M6L0P8-1", "uniprot_id": [ { "id": "A0A0M6L0P8_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A0M6L0P8", "type": "external" } ], "mass": 31984.0, "length": 278, "protein_name": "Growth hormone E5; Prolactin-related protein VII", "gene_name": "GHE5", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GHE5; PRP-VII", "gene_names_refseq": "", "protein_names_uniprotkb": "Growth hormone E5; Prolactin-related protein VII", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "26697363;26862561", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005148 prolactin receptor binding;GO:0046872 metal ion binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0031667 response to nutrient levels;GO:0007565 female pregnancy;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0030879 mammary gland development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0M6L0P8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0M6L0Q6-1", "uniprot_id": [ { "id": "A0A0M6L0Q6_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A0M6L0Q6", "type": "external" } ], "mass": 27414.0, "length": 238, "protein_name": "Growth hormone E4", "gene_name": "GHE4; LOC100298767", "organism": "Bovine", "refseq_name": "chorionic somatomammotropin hormone 2 precursor", "refseq_ac": [ { "id": "NP_001306814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001306814", "type": "external" } ], "gene_names_uniprotkb": "GHE4; LOC100298767; LOC100298767", "gene_names_refseq": "GHE4; LOC100298767", "protein_names_uniprotkb": "Growth hormone E4", "protein_names_refseq": "chorionic somatomammotropin hormone 2 precursor; growth hormone E4", "tax_id": 9913, "disease": "", "pathway": " (bta:100298767)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26697363;26862561", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005148 prolactin receptor binding;GO:0046872 metal ion binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0031667 response to nutrient levels;GO:0007565 female pregnancy;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0030879 mammary gland development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0M6L0Q6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4STX9-1", "uniprot_id": [ { "id": "A0A0N4STX9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N4STX9", "type": "external" } ], "mass": 57871.0, "length": 524, "protein_name": "AT-rich interactive domain-containing protein 3", "gene_name": "arid3a", "organism": "Zebrafish", "refseq_name": "AT-rich interactive domain-containing protein 3A", "refseq_ac": [ { "id": "XP_009304080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304080", "type": "external" } ], "gene_names_uniprotkb": "arid3a", "gene_names_refseq": "arid3a", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 3; ARID domain-containing protein", "protein_names_refseq": "AT-rich interactive domain-containing protein 3A", "tax_id": 7955, "disease": "", "pathway": " (dre:562799)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B3V9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4STX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SU37-1", "uniprot_id": [ { "id": "A0A0N4SU37_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N4SU37", "type": "external" } ], "mass": 64533.0, "length": 588, "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "slco1f3", "organism": "Zebrafish", "refseq_name": "solute carrier organic anion transporter family, member 1F3", "refseq_ac": [ { "id": "NP_001129156", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129156", "type": "external" } ], "gene_names_uniprotkb": "slco1f3; zgc:175035", "gene_names_refseq": "slco1f3; zgc:175035", "protein_names_uniprotkb": "Solute carrier organic anion transporter family member", "protein_names_refseq": "Oatp1f3; solute carrier anion transporting family member 1f3; solute carrier organic anion transporter family, member 1F3", "tax_id": 7955, "disease": "", "pathway": " (dre:100190900); (R-DRE-159418); (R-DRE-879518); (R-DRE-9793528)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "19931635;23594743;24113777;26055554;26308493;30965663", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155311.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from LO018370.1. On Sep 30, 2011 this sequence version replaced NP_001129156.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NIQ7", "ec_number_list": [], "go_molecular_function": "GO:0015347 sodium-independent organic anion transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0043252 sodium-independent organic anion transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0N4SU37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SU47-1", "uniprot_id": [ { "id": "A0A0N4SU47_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N4SU47", "type": "external" } ], "mass": 57952.0, "length": 501, "protein_name": "Cholesterol 24-hydroxylase", "gene_name": "cyp46a1.5", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC641477 isoform 1", "refseq_ac": [ { "id": "NP_001417768", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417768", "type": "external" } ], "gene_names_uniprotkb": "cyp46a1.5; zgc:123299", "gene_names_refseq": "cyp46a1.5; zgc:123299", "protein_names_uniprotkb": "Cholesterol 24-hydroxylase; 1.14.14.25; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; Cytochrome P450 46A1", "protein_names_refseq": "uncharacterized protein LOC641477 isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:641477)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;34356784", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.28860724.1, SRR32588729.29345535.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jun 25, 2025 this sequence version replaced NP_001417768.1., [RefSeq]; P450 monooxygenase that plays a major role in cholesterol homeostasis in the brain. Primarily catalyzes the hydroxylation (with S stereochemistry) at C-24 of cholesterol side chain, triggering cholesterol diffusion out of neurons and its further degradation. By promoting constant cholesterol elimination in neurons, may activate the mevalonate pathway and coordinate the synthesis of new cholesterol and nonsterol isoprenoids involved in synaptic activity and learning. Further hydroxylates cholesterol derivatives and hormone steroids on both the ring and side chain of these molecules, converting them into active oxysterols involved in lipid signaling and biosynthesis. Acts as an epoxidase converting cholesta-5,24-dien-3beta-ol/desmosterol into (24S),25-epoxycholesterol, an abundant lipid ligand of nuclear NR1H2 and NR1H3 receptors shown to promote neurogenesis in developing brain. May also catalyze the oxidative metabolism of xenobiotics, such as clotrimazole., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PSY7", "ec_number_list": [ { "id": "1.14.14.25", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.25", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0033781 cholesterol 24-hydroxylase activity", "go_cellular_component": "GO:0030425 dendrite;GO:0005789 endoplasmic reticulum membrane;GO:0098794 postsynapse;GO:0098793 presynapse", "go_biological_process": "GO:0006707 cholesterol catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0N4SU47-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SU70-1", "uniprot_id": [ { "id": "A0A0N4SU70_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N4SU70", "type": "external" } ], "mass": 44158.0, "length": 403, "protein_name": "Si:ch211-142b24.8", "gene_name": "si:ch211-142b24.8", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-142b24.8 isoform X1", "refseq_ac": [ { "id": "XP_005168078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168078", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-142b24.8", "gene_names_refseq": "si:ch211-142b24.8", "protein_names_uniprotkb": "Si:ch211-142b24.8", "protein_names_refseq": "uncharacterized protein si:ch211-142b24.8 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101886195)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BFH3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SU70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SUA6-1", "uniprot_id": [ { "id": "A0A0N4SUA6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N4SUA6", "type": "external" } ], "mass": 169182.0, "length": 1530, "protein_name": "Protein TOPAZ1", "gene_name": "topaz1", "organism": "Zebrafish", "refseq_name": "protein TOPAZ1 isoform X1", "refseq_ac": [ { "id": "XP_009292759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292759", "type": "external" } ], "gene_names_uniprotkb": "topaz1", "gene_names_refseq": "topaz1", "protein_names_uniprotkb": "Protein TOPAZ1; Testis- and ovary-specific PAZ domain-containing protein 1", "protein_names_refseq": "protein TOPAZ1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101883830)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AVW5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0030154 cell differentiation;GO:0048137 spermatocyte division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SUA6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SUG9-1", "uniprot_id": [ { "id": "A0A0N4SUG9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N4SUG9", "type": "external" } ], "mass": 40563.0, "length": 355, "protein_name": "P2Y purinoceptor 1", "gene_name": "p2ry1", "organism": "Zebrafish", "refseq_name": "P2Y purinoceptor 1", "refseq_ac": [ { "id": "XP_001343355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001343355", "type": "external" } ], "gene_names_uniprotkb": "p2ry1", "gene_names_refseq": "p2ry1", "protein_names_uniprotkb": "P2Y purinoceptor 1; Purinergic receptor", "protein_names_refseq": "P2Y purinoceptor 1", "tax_id": 7955, "disease": "impotence (Disease Ontology:DOID:1875)", "pathway": " (dre:100003922); (R-DRE-416476); (R-DRE-417957); (R-DRE-418592)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PV70", "ec_number_list": [], "go_molecular_function": "GO:0001621 G protein-coupled ADP receptor activity;GO:0031686 A1 adenosine receptor binding;GO:0045031 G protein-coupled ATP receptor activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0090075 relaxation of muscle;GO:0030168 platelet activation;GO:0002250 adaptive immune response;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SUG9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SUH6-1", "uniprot_id": [ { "id": "A0A0N4SUH6_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0N4SUH6", "type": "external" } ], "mass": 19889.0, "length": 174, "protein_name": "RNA-binding protein 8A", "gene_name": "Rbm8a2", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rbm8a2", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding protein 8A", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0035145 exon-exon junction complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SUH6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SUI7-1", "uniprot_id": [ { "id": "A0A0N4SUI7_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0N4SUI7", "type": "external" } ], "mass": 7026.0, "length": 68, "protein_name": "Negative regulator of P-body association", "gene_name": "Nbdy", "organism": "Mouse", "refseq_name": "T helper cell-induced peptide 5", "refseq_ac": [ { "id": "NP_001423324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423324", "type": "external" } ], "gene_names_uniprotkb": "Nbdy; 2210013O21Rik", "gene_names_refseq": "2210013O21Rik; Nbdy; Thp5", "protein_names_uniprotkb": "Negative regulator of P-body association", "protein_names_refseq": "T helper cell-induced peptide 5", "tax_id": 10090, "disease": "", "pathway": " (mmu:70123)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21750661;22130674", "class_list": "", "function": "CD4+ T cell-derived novel peptide Thp5 induces interleukin-4 production in CD4+ T cells to direct T helper 2 cell differentiation., [RefSeq, PubMed]; The protein encoded by this gene is a 68 aa peptide produced by early activated CD4+ T cells. The encoded protein helps regulate the differentiation of these cells into T helper 2 (Th2) cells. 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 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While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0004866 endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SVU1-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SW15-1", "uniprot_id": [ { "id": "A0A0N4SW15_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0N4SW15", "type": "external" } ], "mass": 27118.0, "length": 236, "protein_name": "Spindlin family, member 2G", "gene_name": "Spin2g", "organism": "Mouse", "refseq_name": "spindlin-2A-like", "refseq_ac": [ { "id": "XP_017174162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017174162", "type": "external" } ], "gene_names_uniprotkb": "Spin2g", "gene_names_refseq": "Spin2g", "protein_names_uniprotkb": "Spindlin family, member 2G", "protein_names_refseq": "spindlin-2A-like", "tax_id": 10090, "disease": "", "pathway": " (mmu:108168468)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SW15-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N4SW31-1", "uniprot_id": [ { "id": "A0A0N4SW31_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0N4SW31", "type": "external" } ], "mass": 5381.0, "length": 51, "protein_name": "Matrix metallopeptidase 24 opposite strand transcript 1", "gene_name": "Mmp24os1", "organism": "Mouse", "refseq_name": "protein MMP24OS", "refseq_ac": [ { "id": "NP_001371098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001371098", "type": "external" } ], "gene_names_uniprotkb": "Mmp24os1; BC029722", "gene_names_refseq": "Mmp24os1", "protein_names_uniprotkb": "Matrix metallopeptidase 24 opposite strand transcript 1", "protein_names_refseq": "protein MMP24OS", "tax_id": 10090, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N4SW31-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N5E8A0-1", "uniprot_id": [ { "id": "A0A0N5E8A0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N5E8A0", "type": "external" } ], "mass": 103999.0, "length": 930, "protein_name": "Rubicon autophagy regulator; Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "gene_name": "rubcn", "organism": "Zebrafish", "refseq_name": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "refseq_ac": [ { "id": "XP_005174116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174116", "type": "external" } ], "gene_names_uniprotkb": "rubcn", "gene_names_refseq": "rubcn", "protein_names_uniprotkb": "Rubicon autophagy regulator; Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "protein_names_refseq": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "tax_id": 7955, "disease": "autosomal recessive spinocerebellar ataxia 15 (Disease Ontology:DOID:0080057)", "pathway": " (dre:100000896)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLQ4", "ec_number_list": [], "go_molecular_function": "GO:1901981 phosphatidylinositol phosphate binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005770 late endosome", "go_biological_process": "GO:1901097 negative regulation of autophagosome maturation;GO:0045806 negative regulation of endocytosis;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0N5E8A0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N9E2K8-1", "uniprot_id": [ { "id": "MMP21_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N9E2K8", "type": "external" } ], "mass": 68911.0, "length": 599, "protein_name": "Matrix metallopeptidase-21", "gene_name": "mmp21", "organism": "Zebrafish", "refseq_name": "matrix metallopeptidase-21 precursor", "refseq_ac": [ { "id": "NP_001304682", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304682", "type": "external" } ], "gene_names_uniprotkb": "mmp21", "gene_names_refseq": "MMP-21; mmp21", "protein_names_uniprotkb": "Matrix metallopeptidase-21; 3.4.24.-; MMP-21", "protein_names_refseq": "matrix metallopeptidase-21 precursor; matrix metalloproteinase-21", "tax_id": 7955, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); visceral heterotaxy 7 (Disease Ontology:DOID:0051021)", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "23594743;26429889;26437028", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT207790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN18715708 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KT207790.1. On Dec 8, 2015 this sequence version replaced XP_001342721.4., [RefSeq]; Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0060971 embryonic heart tube left/right pattern formation;GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0007368 determination of left/right symmetry;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0N9E2K8-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000000001.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0N9NUD7-1", "uniprot_id": [ { "id": "A0A0N9NUD7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0N9NUD7", "type": "external" } ], "mass": 37504.0, "length": 341, "protein_name": "Parapinopsin a; Parapinopsin-1", "gene_name": "parapinopsina", "organism": "Zebrafish", "refseq_name": "parapinopsin a", "refseq_ac": [ { "id": "NP_001304685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304685", "type": "external" } ], "gene_names_uniprotkb": "parapinopsina; pp1; uvpp", "gene_names_refseq": "parapinopsina; pp1; uvpp", "protein_names_uniprotkb": "Parapinopsin a; Parapinopsin-1", "protein_names_refseq": "UV sensitive parapinopsin; parapinopsin a; parapinopsin-1", "tax_id": 7955, "disease": "", "pathway": " (dre:100331083)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "20886157;23594743;26370232;26450929;26492337;30322939;32922310;33579376;34526036;34785668", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT008404.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KT008404.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P255", "ec_number_list": [], "go_molecular_function": "GO:0008020 G protein-coupled photoreceptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0016038 absorption of visible light;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007601 visual perception;GO:0007603 phototransduction, visible light;GO:0007602 phototransduction", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0N9NUD7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0P0CP42-1", "uniprot_id": [ { "id": "A0A0P0CP42_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0P0CP42", "type": "external" } ], "mass": 152915.0, "length": 1384, "protein_name": "CARMIL3; Capping protein regulator and myosin 1 linker 3; Capping protein, Arp2/3 and myosin-I linker protein 3", "gene_name": "carmil3", "organism": "Zebrafish", "refseq_name": "capping protein, Arp2/3 and myosin-I linker protein 3", "refseq_ac": [ { "id": "NP_001304694", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304694", "type": "external" } ], "gene_names_uniprotkb": "carmil3; lrrc16b; si:ch211-204d18.1", "gene_names_refseq": "carmil3; lrrc16b; si:ch211-204d18.1", "protein_names_uniprotkb": "CARMIL3; Capping protein regulator and myosin 1 linker 3; Capping protein, Arp2/3 and myosin-I linker protein 3", "protein_names_refseq": "capping protein, Arp2/3 and myosin-I linker protein 3; leucine rich repeat containing 16B", "tax_id": 7955, "disease": "", "pathway": " (dre:100537031)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23594743;26426389;27189481;28252024;34599906", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KR912200.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476739, SAMEA4476740 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KR912200.1., [RefSeq]; CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7B6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:0016477 cell migration;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation;GO:0070121 Kupffer's vesicle development;GO:0061371 determination of heart left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0P0CP42-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9C9-1", "uniprot_id": [ { "id": "A0A0R4I9C9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9C9", "type": "external" } ], "mass": 50528.0, "length": 459, "protein_name": "Dual specificity protein phosphatase 10", "gene_name": "dusp10", "organism": "Zebrafish", "refseq_name": "dual specificity protein phosphatase 10", "refseq_ac": [ { "id": "XP_003200822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200822", "type": "external" } ], "gene_names_uniprotkb": "dusp10", "gene_names_refseq": "dusp10", "protein_names_uniprotkb": "Dual specificity protein phosphatase 10; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 10", "tax_id": 7955, "disease": "", "pathway": " (dre:100034609); (R-DRE-112409); (R-DRE-5675221)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RTC2", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0002682 regulation of immune system process;GO:0046329 negative regulation of JNK cascade;GO:0060284 regulation of cell development;GO:0051239 regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4I9C9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9D6-1", "uniprot_id": [ { "id": "A0A0R4I9D6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9D6", "type": "external" } ], "mass": 139826.0, "length": 1248, "protein_name": "Symplekin", "gene_name": "sympk", "organism": "Zebrafish", "refseq_name": "symplekin isoform X1", "refseq_ac": [ { "id": "XP_699475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699475", "type": "external" } ], "gene_names_uniprotkb": "sympk", "gene_names_refseq": "sympk", "protein_names_uniprotkb": "Symplekin", "protein_names_refseq": "symplekin isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:570858); (R-DRE-73856); (R-DRE-77595); (R-DRE-9770562)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_699475.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVD6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005847 mRNA cleavage and polyadenylation specificity factor complex;GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4I9D6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9E8-1", "uniprot_id": [ { "id": "A0A0R4I9E8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9E8", "type": "external" } ], "mass": 92780.0, "length": 829, "protein_name": "procollagen-proline 3-dioxygenase", "gene_name": "p3h1", "organism": "Zebrafish", "refseq_name": "prolyl 3-hydroxylase 1 isoform X1", "refseq_ac": [ { "id": "XP_002663865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663865", "type": "external" } ], "gene_names_uniprotkb": "p3h1", "gene_names_refseq": "p3h1", "protein_names_uniprotkb": "procollagen-proline 3-dioxygenase; 1.14.11.7", "protein_names_refseq": "prolyl 3-hydroxylase 1 isoform X1", "tax_id": 7955, "disease": "osteogenesis imperfecta type 8 (Disease Ontology:DOID:0110336)", "pathway": " (dre:553321); (R-DRE-1650814)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHI8", "ec_number_list": [ { "id": "1.14.11.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.7", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0031418 L-ascorbic acid binding;GO:0019797 procollagen-proline 3-dioxygenase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0032963 collagen metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4I9E8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9I2-1", "uniprot_id": [ { "id": "A0A0R4I9I2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9I2", "type": "external" } ], "mass": 53205.0, "length": 508, "protein_name": "Cleavage stimulation factor subunit 2 isoform X1; Cleavage stimulation factor, 3' pre-RNA, subunit 2", "gene_name": "cstf2", "organism": "Zebrafish", "refseq_name": "cleavage stimulation factor subunit 2 isoform X1", "refseq_ac": [ { "id": "XP_009289373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289373", "type": "external" } ], "gene_names_uniprotkb": "cstf2; CstF-64; fb11e07; wu:fb11e07; zgc:56346; zgc:77730", "gene_names_refseq": "CstF-64; cstf2; fb11e07; wu:fb11e07; zgc:56346; zgc:77730", "protein_names_uniprotkb": "Cleavage stimulation factor subunit 2 isoform X1; Cleavage stimulation factor, 3' pre-RNA, subunit 2", "protein_names_refseq": "cleavage stimulation factor subunit 2 isoform X1", "tax_id": 7955, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776)", "pathway": " (dre:386806); (R-DRE-73856); (R-DRE-77595); (R-DRE-9770562)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "16542450;18565225;20603019;23594743;26469318;28381614", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AHX3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005847 mRNA cleavage and polyadenylation specificity factor complex;GO:0005634 nucleus", "go_biological_process": "GO:0031124 mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4I9I2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9L6-1", "uniprot_id": [ { "id": "A0A0R4I9L6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9L6", "type": "external" } ], "mass": 93481.0, "length": 837, "protein_name": "Olfactory receptor C family, g3; Olfactory receptor CG3 precursor", "gene_name": "olfcg3", "organism": "Zebrafish", "refseq_name": "olfactory receptor CG3 precursor", "refseq_ac": [ { "id": "NP_001103412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103412", "type": "external" } ], "gene_names_uniprotkb": "olfcg3; si:dkey-245i2.7", "gene_names_refseq": "olfcg3; si:dkey-245i2.7", "protein_names_uniprotkb": "Olfactory receptor C family, g3; Olfactory receptor CG3 precursor", "protein_names_refseq": "A05; Dr9-3; olfactory receptor CG3 precursor; sub 9_9; v2ra5", "tax_id": 7955, "disease": "", "pathway": " (dre:100004682)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.25864253.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Oct 14, 2007 this sequence version replaced XP_001343926.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NEX5", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4I9L6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9L7-1", "uniprot_id": [ { "id": "A0A0R4I9L7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9L7", "type": "external" } ], "mass": 121112.0, "length": 1139, "protein_name": "Sal-like protein 2; Si:ch211-212k18.5", "gene_name": "si:ch211-212k18.5", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-212k18.5", "refseq_ac": [ { "id": "XP_021333427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333427", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-212k18.5", "gene_names_refseq": "si:ch211-212k18.5", "protein_names_uniprotkb": "Sal-like protein 2; Si:ch211-212k18.5", "protein_names_refseq": "uncharacterized protein si:ch211-212k18.5", "tax_id": 7955, "disease": "", "pathway": " (dre:562900)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TB39", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4I9L7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9N0-1", "uniprot_id": [ { "id": "A0A0R4I9N0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9N0", "type": "external" } ], "mass": 31357.0, "length": 279, "protein_name": "Purine-rich element-binding protein Ab; Transcriptional activator protein Pur-alpha", "gene_name": "purab", "organism": "Zebrafish", "refseq_name": "transcriptional activator protein Pur-alpha", "refseq_ac": [ { "id": "XP_005157218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157218", "type": "external" } ], "gene_names_uniprotkb": "purab", "gene_names_refseq": "purab", "protein_names_uniprotkb": "Purine-rich element-binding protein Ab; Transcriptional activator protein Pur-alpha", "protein_names_refseq": "transcriptional activator protein Pur-alpha", "tax_id": 7955, "disease": "autosomal dominant intellectual developmental disorder 31 (Disease Ontology:DOID:0070061)", "pathway": " (dre:557266)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B418", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0032422 purine-rich negative regulatory element binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4I9N0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9N1-1", "uniprot_id": [ { "id": "A0A0R4I9N1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9N1", "type": "external" } ], "mass": 104755.0, "length": 950, "protein_name": "Thrombospondin 4a; Thrombospondin-4a precursor", "gene_name": "thbs4a", "organism": "Zebrafish", "refseq_name": "thrombospondin-4a precursor", "refseq_ac": [ { "id": "NP_001107896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107896", "type": "external" } ], "gene_names_uniprotkb": "thbs4a; zgc:175276", "gene_names_refseq": "thbs4a; zgc:175276", "protein_names_uniprotkb": "Thrombospondin 4a; Thrombospondin-4a precursor", "protein_names_refseq": "thrombospondin-4a precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:563429)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23594743;27189481;35013168;35127702;36452329;37726321", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01040769.1, GDQH01017949.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476750, SAMEA4476752 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Sep 3, 2015 this sequence version replaced NP_001107896.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NHG5", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4I9N1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9S5-1", "uniprot_id": [ { "id": "A0A0R4I9S5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9S5", "type": "external" } ], "mass": 100819.0, "length": 865, "protein_name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit b", "gene_name": "naa15b", "organism": "Zebrafish", "refseq_name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit b", "refseq_ac": [ { "id": "NP_976066", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_976066", "type": "external" } ], "gene_names_uniprotkb": "naa15b; fi31d06; narg1b; wu:fi31d06", "gene_names_refseq": "fi31d06; naa15b; narg1b; wu:fi31d06", "protein_names_uniprotkb": "N-alpha-acetyltransferase 15, NatA auxiliary subunit b", "protein_names_refseq": "N-alpha-acetyltransferase 15, NatA auxiliary subunit b; NMDA receptor-regulated gene 1b; transcriptional coactivator tubedown-100", "tax_id": 7955, "disease": "autosomal dominant intellectual developmental disorder 50 (Disease Ontology:DOID:0080233)", "pathway": " (dre:334099)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15520368;23594743;26469318;27189481;27503704;30502388;30755680", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY391464.1, GFIL01027589.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On or before Jun 11, 2015 this sequence version replaced XP_009291037.1, NP_976066.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PEL4", "ec_number_list": [], "go_molecular_function": "GO:0010698 acetyltransferase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031415 NatA complex", "go_biological_process": "GO:0061055 myotome development", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4I9S5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9W5-1", "uniprot_id": [ { "id": "A0A0R4I9W5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9W5", "type": "external" } ], "mass": 20216.0, "length": 180, "protein_name": "MADF domain-containing protein; Si:ch73-59f11.3", "gene_name": "si:ch73-59f11.3", "organism": "Zebrafish", "refseq_name": "MADF domain-containing protein", "refseq_ac": [ { "id": "NP_001315046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315046", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-59f11.3", "gene_names_refseq": "si:ch73-59f11.3", "protein_names_uniprotkb": "MADF domain-containing protein; Si:ch73-59f11.3", "protein_names_refseq": "MADF domain-containing protein", "tax_id": 7955, "disease": "", "pathway": " (dre:107988036)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CN327033.1, EH529860.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4E0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4I9W5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4I9Y1-1", "uniprot_id": [ { "id": "R213B_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4I9Y1", "type": "external" } ], "mass": 577550.0, "length": 5061, "protein_name": "E3 ubiquitin-protein ligase rnf213-beta", "gene_name": "rnf213b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rnf213b", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase rnf213-beta; 2.3.2.-; 2.3.2.27; 3.6.4.-; E3 ubiquitin-lipopolysaccharide ligase rnf213-beta; Mysterin-B; Mysterin-beta; RING finger protein 213-B; RING finger protein 213-beta", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "21799892;23594743;26530008", "class_list": "", "function": "Atypical E3 ubiquitin ligase that can catalyze ubiquitination of both proteins and lipids, and which is involved in various processes, such as lipid metabolism, angiogenesis and cell-autonomous immunity. Acts as a key immune sensor by catalyzing ubiquitination of the lipid A moiety of bacterial lipopolysaccharide (LPS) via its RZ-type zinc-finger: restricts the proliferation of cytosolic bacteria, such as Salmonella, by generating the bacterial ubiquitin coat through the ubiquitination of LPS. Ubiquitination of LPS triggers cell-autonomous immunity, such as antibacterial autophagy, leading to degradation of the microbial invader (By similarity). Involved in lipid metabolism by regulating fat storage and lipid droplet formation; act by inhibiting the lipolytic process (By similarity). Also regulates lipotoxicity by inhibiting desaturation of fatty acids. Also acts as an E3 ubiquitin-protein ligase via its RING-type zinc finger. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of proteins downstream of rspo3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity; ATPase activity is required for ubiquitination of LPS (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005811 lipid droplet;GO:0005829 cytosol", "go_biological_process": "GO:0019216 regulation of lipid metabolic process;GO:0098792 xenophagy;GO:0042742 defense response to bacterium;GO:0002040 sprouting angiogenesis;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4I9Y1-1", "record_type": "protein", "filter_code": "0000000.0000100.000100.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IA74-1", "uniprot_id": [ { "id": "A0A0R4IA74_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IA74", "type": "external" } ], "mass": 29339.0, "length": 257, "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "utp23", "organism": "Zebrafish", "refseq_name": "rRNA-processing protein UTP23 homolog isoform X1", "refseq_ac": [ { "id": "XP_068071228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071228", "type": "external" } ], "gene_names_uniprotkb": "utp23; fc04b12; wu:fc04b12; zgc:110214", "gene_names_refseq": "fc04b12; utp23; wu:fc04b12; zgc:110214", "protein_names_uniprotkb": "rRNA-processing protein UTP23 homolog", "protein_names_refseq": "rRNA-processing protein UTP23 homolog isoform X1", "tax_id": 7955, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861)", "pathway": " (dre:550514)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in rRNA-processing and ribosome biogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B3U5", "ec_number_list": [], "go_molecular_function": "GO:0070181 small ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IA74-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IA89-1", "uniprot_id": [ { "id": "A0A0R4IA89_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IA89", "type": "external" } ], "mass": 119466.0, "length": 1048, "protein_name": "NLR family CARD domain-containing protein 3; Si:dkey-27n6.1", "gene_name": "si:ch211-203c5.3; si:dkey-27n6.1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:ch211-203c5.3; si:dkey-27n6.1; LOC796962; si:dkey-27n6.1", "gene_names_refseq": "", "protein_names_uniprotkb": "NLR family CARD domain-containing protein 3; Si:dkey-27n6.1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100034375); (dre:110439605); (dre:796962)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q268", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IA89-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAC3-1", "uniprot_id": [ { "id": "A0A0R4IAC3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAC3", "type": "external" } ], "mass": 46651.0, "length": 405, "protein_name": "SEC14-like lipid-binding 7; SEC14-like protein 2", "gene_name": "sec14l7", "organism": "Zebrafish", "refseq_name": "SEC14-like protein 2", "refseq_ac": [ { "id": "XP_009303977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303977", "type": "external" } ], "gene_names_uniprotkb": "sec14l7", "gene_names_refseq": "sec14l7", "protein_names_uniprotkb": "SEC14-like lipid-binding 7; SEC14-like protein 2", "protein_names_refseq": "SEC14-like protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:566865)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B6M1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IAC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAD0-1", "uniprot_id": [ { "id": "A0A0R4IAD0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAD0", "type": "external" } ], "mass": 48785.0, "length": 425, "protein_name": "G protein-activated inward rectifier potassium channel 4; Potassium inwardly rectifying channel subfamily J member 5", "gene_name": "kcnj5", "organism": "Zebrafish", "refseq_name": "G protein-activated inward rectifier potassium channel 4", "refseq_ac": [ { "id": "XP_700619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700619", "type": "external" } ], "gene_names_uniprotkb": "kcnj5", "gene_names_refseq": "kcnj5", "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 4; Potassium inwardly rectifying channel subfamily J member 5", "protein_names_refseq": "G protein-activated inward rectifier potassium channel 4", "tax_id": 7955, "disease": "atrial fibrillation (Disease Ontology:DOID:0060224); long QT syndrome 13 (Disease Ontology:DOID:0110654); primary hyperaldosteronism (Disease Ontology:DOID:446)", "pathway": " (dre:571888)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_700619.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UW41", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0007399 nervous system development;GO:0034765 regulation of monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IAD0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAE2-1", "uniprot_id": [ { "id": "A0A0R4IAE2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAE2", "type": "external" } ], "mass": 123944.0, "length": 1094, "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3", "gene_name": "srgap3", "organism": "Zebrafish", "refseq_name": "SLIT-ROBO Rho GTPase-activating protein 3 isoform X1", "refseq_ac": [ { "id": "XP_005166172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166172", "type": "external" } ], "gene_names_uniprotkb": "srgap3", "gene_names_refseq": "srgap3", "protein_names_uniprotkb": "SLIT-ROBO Rho GTPase-activating protein 3; Rho GTPase-activating protein 14; WAVE-associated Rac GTPase-activating protein", "protein_names_refseq": "SLIT-ROBO Rho GTPase-activating protein 3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:561567); (R-DRE-9013148); (R-DRE-9013149)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDL4", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0045202 synapse", "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0030336 negative regulation of cell migration;GO:0051963 regulation of synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IAE2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAF6-1", "uniprot_id": [ { "id": "A0A0R4IAF6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAF6", "type": "external" } ], "mass": 216009.0, "length": 1876, "protein_name": "Proteasome activator complex subunit 4A", "gene_name": "psme4a", "organism": "Zebrafish", "refseq_name": "proteasome activator complex subunit 4A", "refseq_ac": [ { "id": "NP_001410925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410925", "type": "external" } ], "gene_names_uniprotkb": "psme4a; si:ch73-101f17.1", "gene_names_refseq": "psme4a; si:ch73-101f17.1", "protein_names_uniprotkb": "Proteasome activator complex subunit 4A", "protein_names_refseq": "proteasome (prosome, macropain) activator subunit 4a; proteasome activator PA200-A; proteasome activator complex subunit 4A", "tax_id": 7955, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545)", "pathway": " (dre:793897)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;26271038;32651405;36768797", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01018484.1, SRR32588733.1803133.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476757 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Aug 28, 2023 this sequence version replaced XP_009305766.1., [RefSeq]; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AZD7", "ec_number_list": [], "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0000502 proteasome complex", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IAF6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAH0-1", "uniprot_id": [ { "id": "A0A0R4IAH0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAH0", "type": "external" } ], "mass": 116426.0, "length": 1052, "protein_name": "Histone deacetylase", "gene_name": "hdac4", "organism": "Zebrafish", "refseq_name": "histone deacetylase 4 isoform X1", "refseq_ac": [ { "id": "XP_005172586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172586", "type": "external" } ], "gene_names_uniprotkb": "hdac4; wu:fa96d08; wu:fc56f08; zgc:152701", "gene_names_refseq": "hdac4; wu:fa96d08; wu:fc56f08; zgc:152701", "protein_names_uniprotkb": "Histone deacetylase; 3.5.1.98", "protein_names_refseq": "histone deacetylase 4 isoform X1", "tax_id": 7955, "disease": "ataxia telangiectasia (Disease Ontology:DOID:12704); impotence (Disease Ontology:DOID:1875); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); aortic aneurysm (Disease Ontology:DOID:3627); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); retinal degeneration (Disease Ontology:DOID:8466); eating disorder (Disease Ontology:DOID:8670); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:568877); (R-DRE-4090294); (R-DRE-4551638); (R-DRE-8951936)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "21773810;22676467;23594743;24240475;25189256;25603810;31792261;32240749;32344037;32380281;33499374", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJV4", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" }, { "id": "3.4.13.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.9", "type": "external" }, { "id": "3.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.-", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004407 histone deacetylase activity;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000118 histone deacetylase complex;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001755 neural crest cell migration;GO:0048701 embryonic cranial skeleton morphogenesis;GO:0040029 epigenetic regulation of gene expression;GO:0036073 perichondral ossification", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IAH0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAN7-1", "uniprot_id": [ { "id": "A0A0R4IAN7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAN7", "type": "external" } ], "mass": 33636.0, "length": 301, "protein_name": "Uncharacterized protein isoform X1; Zgc:174863", "gene_name": "zgc:174863", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_005166230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166230", "type": "external" } ], "gene_names_uniprotkb": "zgc:174863", "gene_names_refseq": "zgc:174863", "protein_names_uniprotkb": "Uncharacterized protein isoform X1; Zgc:174863", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100136852)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27409813;33287696", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDR4", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IAN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAP0-1", "uniprot_id": [ { "id": "A0A0R4IAP0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAP0", "type": "external" } ], "mass": 62824.0, "length": 560, "protein_name": "alpha-1,2-Mannosidase", "gene_name": "edem2", "organism": "Zebrafish", "refseq_name": "ER degradation-enhancing alpha-mannosidase-like protein 2 precursor", "refseq_ac": [ { "id": "NP_001292543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292543", "type": "external" } ], "gene_names_uniprotkb": "edem2", "gene_names_refseq": "edem2", "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-", "protein_names_refseq": "ER degradation-enhancing alpha-mannosidase-like protein 2 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:402801)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23594743;25253178;26469318;29778665;36768797", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01009155.1, BC055547.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2. Seems to recognize and bind to exposed hydrophobic regions in target proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1W0", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0044322 endoplasmic reticulum quality control compartment", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0030968 endoplasmic reticulum unfolded protein response;GO:1904380 endoplasmic reticulum mannose trimming;GO:1904154 positive regulation of retrograde protein transport, ER to cytosol;GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IAP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAR1-1", "uniprot_id": [ { "id": "A0A0R4IAR1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAR1", "type": "external" } ], "mass": 21045.0, "length": 198, "protein_name": "Lymphocyte antigen 6 family member M2", "gene_name": "ly6m2", "organism": "Zebrafish", "refseq_name": "lymphocyte antigen 6 family member M2 precursor", "refseq_ac": [ { "id": "NP_001373263", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373263", "type": "external" } ], "gene_names_uniprotkb": "ly6m2; ly21.2; si:ch211-134a4.1", "gene_names_refseq": "ly21.2; ly6m2; si:ch211-134a4.1", "protein_names_uniprotkb": "Lymphocyte antigen 6 family member M2", "protein_names_refseq": "lymphocyte antigen 6 family member M2 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100333489)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22415300;23594743;26113395;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01017572.1, SRR32588718.1119710.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 21, 2020 this sequence version replaced XP_002665293.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHT4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IAR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAR3-1", "uniprot_id": [ { "id": "A0A0R4IAR3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAR3", "type": "external" } ], "mass": 24904.0, "length": 218, "protein_name": "RAB42, member RAS oncogene family; Ras-related protein Rab-42b", "gene_name": "rab42b", "organism": "Zebrafish", "refseq_name": "ras-related protein Rab-42b", "refseq_ac": [ { "id": "NP_001017683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017683", "type": "external" } ], "gene_names_uniprotkb": "rab42b; zgc:112009", "gene_names_refseq": "rab42b; zgc:112009", "protein_names_uniprotkb": "RAB42, member RAS oncogene family; Ras-related protein Rab-42b", "protein_names_refseq": "ras-related protein Rab-42b", "tax_id": 7955, "disease": "", "pathway": " (dre:550378)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;27189481;28396820;28626217", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155736.1, BC093158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC155736.1. On Sep 30, 2011 this sequence version replaced NP_001017683.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N550", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IAR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAS2-1", "uniprot_id": [ { "id": "A0A0R4IAS2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAS2", "type": "external" } ], "mass": 207025.0, "length": 1754, "protein_name": "Periplakin", "gene_name": "ppl", "organism": "Zebrafish", "refseq_name": "periplakin isoform X2", "refseq_ac": [ { "id": "XP_005164160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164160", "type": "external" } ], "gene_names_uniprotkb": "ppl; cb180; im:7140067; im:7149519; sb:cb180", "gene_names_refseq": "cb180; im:7140067; im:7149519; ppl; sb:cb180", "protein_names_uniprotkb": "Periplakin", "protein_names_refseq": "periplakin isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:449936); (R-DRE-6809371)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "22931925;23594743;26469318;31683705;32031521;32894222;35325106", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBC1", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0001533 cornified envelope;GO:0030057 desmosome", "go_biological_process": "GO:0031424 keratinization;GO:0042060 wound healing;GO:0045104 intermediate filament cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IAS2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAT4-1", "uniprot_id": [ { "id": "A0A0R4IAT4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAT4", "type": "external" } ], "mass": 50520.0, "length": 459, "protein_name": "NOP2/Sun RNA methyltransferase 6; tRNA (Cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1", "gene_name": "nsun6", "organism": "Zebrafish", "refseq_name": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1", "refseq_ac": [ { "id": "XP_005169112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169112", "type": "external" } ], "gene_names_uniprotkb": "nsun6", "gene_names_refseq": "nsun6", "protein_names_uniprotkb": "NOP2/Sun RNA methyltransferase 6; tRNA (Cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1", "protein_names_refseq": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1", "tax_id": 7955, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); autosomal recessive intellectual developmental disorder 82 (Disease Ontology:DOID:0060947)", "pathway": " (dre:100149557)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGC6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008173 RNA methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0001510 RNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IAT4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAV9-1", "uniprot_id": [ { "id": "A0A0R4IAV9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAV9", "type": "external" } ], "mass": 148833.0, "length": 1351, "protein_name": "SUN domain-containing ossification factor", "gene_name": "suco", "organism": "Zebrafish", "refseq_name": "SUN domain-containing ossification factor isoform X1", "refseq_ac": [ { "id": "XP_005160501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160501", "type": "external" } ], "gene_names_uniprotkb": "suco", "gene_names_refseq": "suco", "protein_names_uniprotkb": "SUN domain-containing ossification factor; Membrane protein CH1; SUN-like protein 1", "protein_names_refseq": "SUN domain-containing ossification factor isoform X1", "tax_id": 7955, "disease": "osteogenesis imperfecta type 5 (Disease Ontology:DOID:0110344)", "pathway": " (dre:558218)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B794", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030867 rough endoplasmic reticulum membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001503 ossification;GO:0046850 regulation of bone remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IAV9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAX4-1", "uniprot_id": [ { "id": "A0A0R4IAX4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAX4", "type": "external" } ], "mass": 16550.0, "length": 153, "protein_name": "Transmembrane protein 42a", "gene_name": "tmem42a", "organism": "Zebrafish", "refseq_name": "transmembrane protein 42a precursor", "refseq_ac": [ { "id": "NP_001373334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373334", "type": "external" } ], "gene_names_uniprotkb": "tmem42a; im:7153990; si:dkey-99n20.7", "gene_names_refseq": "im:7153990; si:dkey-99n20.7; tmem42a", "protein_names_uniprotkb": "Transmembrane protein 42a", "protein_names_refseq": "transmembrane protein 42a precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100329298)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01016446.1, GDQQ01029393.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476732, SAMEA4476769 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR925805.15. On Aug 21, 2020 this sequence version replaced XP_002665001.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RRJ1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IAX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAX5-1", "uniprot_id": [ { "id": "A0A0R4IAX5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAX5", "type": "external" } ], "mass": 62486.0, "length": 549, "protein_name": "malate synthase", "gene_name": "ugl", "organism": "Zebrafish", "refseq_name": "malate synthase-like", "refseq_ac": [ { "id": "NP_001188337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188337", "type": "external" } ], "gene_names_uniprotkb": "ugl; mlsl; zmp:0000000758", "gene_names_refseq": "mlsl; ugl; zmp:0000000758", "protein_names_uniprotkb": "malate synthase; 2.3.3.9", "protein_names_refseq": "malate synthase-like", "tax_id": 7955, "disease": "", "pathway": " (dre:564844)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23594743;26469318;27189481;27941970;35295584", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122227.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH433561.1, EH488762.1, EH537783.1 and EH515288.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3F0", "ec_number_list": [ { "id": "2.3.3.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.9", "type": "external" }, { "id": "4.1.3.25", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.25", "type": "external" }, { "id": "3.1.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.30", "type": "external" } ], "go_molecular_function": "GO:0004474 malate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006097 glyoxylate cycle", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IAX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IAZ1-1", "uniprot_id": [ { "id": "A0A0R4IAZ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IAZ1", "type": "external" } ], "mass": 30225.0, "length": 260, "protein_name": "SLX1 homolog B, structure-specific endonuclease subunit; Structure-specific endonuclease subunit SLX1", "gene_name": "slx1b", "organism": "Zebrafish", "refseq_name": "structure-specific endonuclease subunit SLX1", "refseq_ac": [ { "id": "NP_001314786", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314786", "type": "external" } ], "gene_names_uniprotkb": "slx1b", "gene_names_refseq": "slx1b", "protein_names_uniprotkb": "SLX1 homolog B, structure-specific endonuclease subunit; Structure-specific endonuclease subunit SLX1", "protein_names_refseq": "SLX1 structure-specific endonuclease subunit homolog B; structure-specific endonuclease subunit SLX1; zmp:0000000823", "tax_id": 7955, "disease": "Fanconi-like syndrome (Disease Ontology:DOID:0090066)", "pathway": " (dre:100001845); (R-DRE-5693568); (R-DRE-6783310)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;34390914", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019200.1, GFIL01014801.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 27, 2016 this sequence version replaced XP_001337124.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P343", "ec_number_list": [], "go_molecular_function": "GO:0008821 crossover junction DNA endonuclease activity;GO:0017108 5'-flap endonuclease activity", "go_cellular_component": "GO:0033557 Slx1-Slx4 complex", "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IAZ1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB00-1", "uniprot_id": [ { "id": "A0A0R4IB00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB00", "type": "external" } ], "mass": 68960.0, "length": 613, "protein_name": "Matrix metallopeptidase 17b; Matrix metalloproteinase-17b isoform 1 precursor", "gene_name": "mmp17b", "organism": "Zebrafish", "refseq_name": "matrix metalloproteinase-17b isoform 1 precursor", "refseq_ac": [ { "id": "NP_001352431", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352431", "type": "external" } ], "gene_names_uniprotkb": "mmp17b; mmpl2; sb:eu434; si:ch211-199b20.1", "gene_names_refseq": "mmp17b; mmpl2; sb:eu434; si:ch211-199b20.1", "protein_names_uniprotkb": "Matrix metallopeptidase 17b; Matrix metalloproteinase-17b isoform 1 precursor", "protein_names_refseq": "MMPLd; matrix metallopeptidase like 2; matrix metalloproteinase-17b isoform 1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100322027); (R-DRE-1592389); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "17439641;19929220;23594743;24098510;26908177;27189481;28837622;30405119;33554855;33951474;37426341", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588714.37648867.1, SRR32588733.1469454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505390, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 30, 2018 this sequence version replaced XP_002664536.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Mmp17b is essential for proper neural crest cell migration in vivo. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RRF6", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0001755 neural crest cell migration;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IB00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB08-1", "uniprot_id": [ { "id": "A0A0R4IB08_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB08", "type": "external" } ], "mass": 85814.0, "length": 759, "protein_name": "C-Jun-amino-terminal kinase-interacting protein 1a; Mitogen-activated protein kinase 8-interacting protein 1a", "gene_name": "mapk8ip1a", "organism": "Zebrafish", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 1a", "refseq_ac": [ { "id": "NP_001338595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338595", "type": "external" } ], "gene_names_uniprotkb": "mapk8ip1a; mapk8ip1", "gene_names_refseq": "mapk8ip1a; mapk8ip1", "protein_names_uniprotkb": "C-Jun-amino-terminal kinase-interacting protein 1a; Mitogen-activated protein kinase 8-interacting protein 1a", "protein_names_refseq": "C-Jun-amino-terminal kinase-interacting protein 1a; mitogen-activated protein kinase 8 interacting protein 1", "tax_id": 7955, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:100537717)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;27614751", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.861492.1, SRR32588717.20249067.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 25, 2025 this sequence version replaced NP_001338595.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PAR0", "ec_number_list": [], "go_molecular_function": "GO:0005078 MAP-kinase scaffold activity;GO:0016301 kinase activity;GO:0008432 JUN kinase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007254 JNK cascade;GO:0046328 regulation of JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IB08-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB13-1", "uniprot_id": [ { "id": "A0A0R4IB13_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB13", "type": "external" } ], "mass": 81884.0, "length": 727, "protein_name": "X-ray repair cross-complementing protein 5", "gene_name": "xrcc5", "organism": "Zebrafish", "refseq_name": "X-ray repair cross-complementing protein 5", "refseq_ac": [ { "id": "NP_001017360", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017360", "type": "external" } ], "gene_names_uniprotkb": "xrcc5; Ku80; im:7137560; si:ch211-239d11.4", "gene_names_refseq": "Ku80; im:7137560; si:ch211-239d11.4; xrcc5", "protein_names_uniprotkb": "X-ray repair cross-complementing protein 5; 3.6.4.-", "protein_names_refseq": "DNA binding protein; X-ray repair cross-complementing protein 5", "tax_id": 7955, "disease": "squamous cell carcinoma (Disease Ontology:DOID:1749); rectum cancer (Disease Ontology:DOID:1993); basal cell carcinoma (Disease Ontology:DOID:2513); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (dre:449848); (R-DRE-5693571); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "15914672;17638406;18764902;19328561;20047468;23594743;30955321;31043511;31462198;33598573;34798058", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY877316.1, GDQH01005405.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR339053.18 and CR392344.9. On Jun 13, 2015 this sequence version replaced NP_001017360.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Single-stranded DNA-dependent ATP-dependent helicase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N4T7", "ec_number_list": [ { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.1.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "5.3.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.2.1", "type": "external" }, { "id": "5.3.3.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.12", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "4.1.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.4", "type": "external" }, { "id": "3.4.21.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.46", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0042162 telomeric DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0043066 negative regulation of apoptotic process;GO:0000723 telomere maintenance;GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IB13-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB27-1", "uniprot_id": [ { "id": "A0A0R4IB27_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB27", "type": "external" } ], "mass": 35635.0, "length": 308, "protein_name": "Si:dkey-31c13.1; Uncharacterized protein LOC100002197 isoform 1", "gene_name": "si:dkey-31c13.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100002197 isoform 1", "refseq_ac": [ { "id": "NP_001373190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373190", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-31c13.1", "gene_names_refseq": "si:dkey-31c13.1", "protein_names_uniprotkb": "Si:dkey-31c13.1; Uncharacterized protein LOC100002197 isoform 1", "protein_names_refseq": "uncharacterized protein LOC100002197 isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:100002197)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01031164.1, EH451769.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 15, 2020 this sequence version replaced XP_009289800.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ASJ2", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IB27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB28-1", "uniprot_id": [ { "id": "A0A0R4IB28_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB28", "type": "external" } ], "mass": 69455.0, "length": 619, "protein_name": "Hypoxia inducible factor 1 subunit alpha, like isoform X1; Hypoxia-inducible factor 1 subunit alpha,-like", "gene_name": "hif1al", "organism": "Zebrafish", "refseq_name": "hypoxia inducible factor 1 subunit alpha, like isoform X1", "refseq_ac": [ { "id": "XP_005157629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157629", "type": "external" } ], "gene_names_uniprotkb": "hif1al; Hif-3alpha; zgc:63965", "gene_names_refseq": "Hif-3alpha; hif1al; zgc:63965", "protein_names_uniprotkb": "Hypoxia inducible factor 1 subunit alpha, like isoform X1; Hypoxia-inducible factor 1 subunit alpha,-like", "protein_names_refseq": "hypoxia inducible factor 1 subunit alpha, like isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:393376)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "19123687;19449054;20571107;21343420;23034716;23594743;34439993;34749790;35269817;36846912;37002435", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_005157629.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3Q6", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0000976 transcription cis-regulatory region binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990907 beta-catenin-TCF complex", "go_biological_process": "GO:0051402 neuron apoptotic process;GO:0001666 response to hypoxia;GO:0006355 regulation of DNA-templated transcription;GO:0014823 response to activity;GO:0048821 erythrocyte development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IB28-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB47-1", "uniprot_id": [ { "id": "A0A0R4IB47_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB47", "type": "external" } ], "mass": 17522.0, "length": 159, "protein_name": "Dispanin subfamily A member 2b-like; Si:ch73-343g19.4", "gene_name": "si:ch73-343g19.4", "organism": "Zebrafish", "refseq_name": "dispanin subfamily A member 2b-like", "refseq_ac": [ { "id": "NP_001373338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373338", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-343g19.4", "gene_names_refseq": "si:ch73-343g19.4", "protein_names_uniprotkb": "Dispanin subfamily A member 2b-like; Si:ch73-343g19.4", "protein_names_refseq": "dispanin subfamily A member 2b-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100535926)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH472544.1, EH446691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Aug 21, 2020 this sequence version replaced XP_009290909.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AQZ9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IB47-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB49-1", "uniprot_id": [ { "id": "A0A0R4IB49_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB49", "type": "external" } ], "mass": 67553.0, "length": 594, "protein_name": "Si:ch211-166e11.5; Sterile alpha motif domain-containing protein 3", "gene_name": "si:ch211-166e11.5", "organism": "Zebrafish", "refseq_name": "sterile alpha motif domain-containing protein 3", "refseq_ac": [ { "id": "XP_002663322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663322", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-166e11.5", "gene_names_refseq": "si:ch211-166e11.5", "protein_names_uniprotkb": "Si:ch211-166e11.5; Sterile alpha motif domain-containing protein 3", "protein_names_refseq": "sterile alpha motif domain-containing protein 3", "tax_id": 7955, "disease": "", "pathway": " (dre:100334858)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RR65", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IB49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB64-1", "uniprot_id": [ { "id": "A0A0R4IB64_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB64", "type": "external" } ], "mass": 34566.0, "length": 292, "protein_name": "Si:ch211-197h24.8", "gene_name": "si:ch211-197h24.8", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-197h24.8", "refseq_ac": [ { "id": "XP_003200245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200245", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-197h24.8", "gene_names_refseq": "si:ch211-197h24.8", "protein_names_uniprotkb": "Si:ch211-197h24.8", "protein_names_refseq": "uncharacterized protein si:ch211-197h24.8", "tax_id": 7955, "disease": "", "pathway": " (dre:100534935)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RNW6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IB64-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB81-1", "uniprot_id": [ { "id": "A0A0R4IB81_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB81", "type": "external" } ], "mass": 33533.0, "length": 300, "protein_name": "Uncharacterized protein LOC503764 precursor; Zgc:112964", "gene_name": "fb93d07", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC503764 precursor", "refseq_ac": [ { "id": "NP_001314798", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314798", "type": "external" } ], "gene_names_uniprotkb": "fb93d07; si:ch73-329n5.4; wu:fb93d07; zgc:112964", "gene_names_refseq": "fb93d07; si:ch73-329n5.4; wu:fb93d07; zgc:112964", "protein_names_uniprotkb": "Uncharacterized protein LOC503764 precursor; Zgc:112964", "protein_names_refseq": "uncharacterized protein LOC503764 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:503764)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC090736.1, SRR32588723.2758514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMEA898401 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1 and AI722397.1. On May 27, 2016 this sequence version replaced XP_005156477.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P350", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007160 cell-matrix adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IB81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB86-1", "uniprot_id": [ { "id": "A0A0R4IB86_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB86", "type": "external" } ], "mass": 28202.0, "length": 244, "protein_name": "Si:dkeyp-53d3.3; Uncharacterized protein LOC562337", "gene_name": "si:dkeyp-53d3.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC562337", "refseq_ac": [ { "id": "NP_001082865", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082865", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-53d3.3", "gene_names_refseq": "si:dkeyp-53d3.3", "protein_names_uniprotkb": "Si:dkeyp-53d3.3; Uncharacterized protein LOC562337", "protein_names_refseq": "uncharacterized protein LOC562337", "tax_id": 7955, "disease": "", "pathway": " (dre:562337)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH508472.1, BC135079.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476731, SAMEA4476739 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH543780.1 and EH508472.1. On Jan 21, 2011 this sequence version replaced NP_001082865.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NE79", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IB86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB87-1", "uniprot_id": [ { "id": "A0A0R4IB87_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB87", "type": "external" } ], "mass": 28465.0, "length": 262, "protein_name": "Si:ch211-155m12.1; Uncharacterized protein LOC567653 precursor", "gene_name": "si:ch211-155m12.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC567653 precursor", "refseq_ac": [ { "id": "NP_001082885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082885", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-155m12.1", "gene_names_refseq": "si:ch211-155m12.1", "protein_names_uniprotkb": "Si:ch211-155m12.1; Uncharacterized protein LOC567653 precursor", "protein_names_refseq": "uncharacterized protein LOC567653 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:567653)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007172.1, BI876486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476764, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On May 24, 2007 this sequence version replaced XP_706417.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NCZ3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IB87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IB93-1", "uniprot_id": [ { "id": "UBP48_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IB93", "type": "external" } ], "mass": 120405.0, "length": 1047, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48", "gene_name": "usp48", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "usp48", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 48; 3.4.19.12; Ubiquitin specific peptidase 48", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100332674); (R-DRE-5689880)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;34059922", "class_list": "", "function": "Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BK68", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0010996 response to auditory stimulus;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IB93-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBA4-1", "uniprot_id": [ { "id": "A0A0R4IBA4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBA4", "type": "external" } ], "mass": 46622.0, "length": 419, "protein_name": "Kynurenine--oxoglutarate transaminase 3", "gene_name": "kyat3.1", "organism": "Zebrafish", "refseq_name": "kynurenine--oxoglutarate transaminase 3", "refseq_ac": [ { "id": "XP_699860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699860", "type": "external" } ], "gene_names_uniprotkb": "kyat3.1", "gene_names_refseq": "kyat3.1", "protein_names_uniprotkb": "Kynurenine--oxoglutarate transaminase 3; 2.6.1.63; 2.6.1.7; 4.4.1.13; Cysteine-S-conjugate beta-lyase 2; Kynurenine aminotransferase 3; Kynurenine aminotransferase III; Kynurenine--glyoxylate transaminase; Kynurenine--oxoglutarate transaminase III", "protein_names_refseq": "kynurenine--oxoglutarate transaminase 3", "tax_id": 7955, "disease": "", "pathway": " (dre:571201)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_699860.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFT2", "ec_number_list": [ { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.63", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.63", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0047315 kynurenine-glyoxylate transaminase activity;GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0047804 cysteine-S-conjugate beta-lyase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0097053 L-kynurenine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IBA4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBA6-1", "uniprot_id": [ { "id": "A0A0R4IBA6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBA6", "type": "external" } ], "mass": 25495.0, "length": 227, "protein_name": "Si:zfos-741a10.3; Uncharacterized protein LOC796591 precursor; Uncharacterized protein isoform X1", "gene_name": "si:zfos-741a10.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC796591 precursor", "refseq_ac": [ { "id": "NP_001373246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373246", "type": "external" } ], "gene_names_uniprotkb": "si:zfos-741a10.3", "gene_names_refseq": "si:zfos-741a10.3", "protein_names_uniprotkb": "Si:zfos-741a10.3; Uncharacterized protein LOC796591 precursor; Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein LOC796591 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:796591)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01024065.1, GFIL01025061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 19, 2020 this sequence version replaced XP_001334154.3., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PUA2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0006955 immune response;GO:0046847 filopodium assembly;GO:1904891 positive regulation of excitatory synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IBA6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBE2-1", "uniprot_id": [ { "id": "A0A0R4IBE2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBE2", "type": "external" } ], "mass": 111513.0, "length": 1024, "protein_name": "Proline-rich transmembrane protein 4; Si:dkey-31f5.11", "gene_name": "prrt4b", "organism": "Zebrafish", "refseq_name": "proline-rich transmembrane protein 4", "refseq_ac": [ { "id": "XP_005164842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164842", "type": "external" } ], "gene_names_uniprotkb": "prrt4b", "gene_names_refseq": "prrt4b", "protein_names_uniprotkb": "Proline-rich transmembrane protein 4; Si:dkey-31f5.11", "protein_names_refseq": "proline-rich transmembrane protein 4", "tax_id": 7955, "disease": "", "pathway": " (dre:335883)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBY6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IBE2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBI5-1", "uniprot_id": [ { "id": "A0A0R4IBI5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBI5", "type": "external" } ], "mass": 12383.0, "length": 110, "protein_name": "Si:dkey-247k7.2; Uncharacterized protein LOC797677 precursor", "gene_name": "si:dkey-247k7.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC797677 precursor", "refseq_ac": [ { "id": "NP_001373287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373287", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-247k7.2; fk35f04; wu:fk35f04", "gene_names_refseq": "fk35f04; si:dkey-247k7.2; wu:fk35f04", "protein_names_uniprotkb": "Si:dkey-247k7.2; Uncharacterized protein LOC797677 precursor", "protein_names_refseq": "uncharacterized protein LOC797677 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:797677)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "20181659;22273551;23458150;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DT075677.1, GDQH01003196.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476815 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Aug 21, 2020 this sequence version replaced XP_001338145.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q1N1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IBI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBJ2-1", "uniprot_id": [ { "id": "A0A0R4IBJ2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBJ2", "type": "external" } ], "mass": 44014.0, "length": 383, "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "bxdc2", "organism": "Zebrafish", "refseq_name": "ribosome biogenesis protein BRX1 homolog", "refseq_ac": [ { "id": "NP_001166027", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166027", "type": "external" } ], "gene_names_uniprotkb": "bxdc2", "gene_names_refseq": "bxdc2", "protein_names_uniprotkb": "Ribosome biogenesis protein BRX1 homolog; Brix domain-containing protein 2", "protein_names_refseq": "ribosome biogenesis protein BRX1 homolog", "tax_id": 7955, "disease": "", "pathway": " (dre:402823)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;24198278;26566657;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC056279.1, EH497128.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EG567403.1, EH513454.1 and BC056279.1. On Apr 26, 2010 this sequence version replaced XP_001921138.2., [RefSeq]; Required for biogenesis of the 60S ribosomal subunit., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NVZ7", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0006364 rRNA processing;GO:0000027 ribosomal large subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IBJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBK5-1", "uniprot_id": [ { "id": "R213A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBK5", "type": "external" } ], "mass": 596751.0, "length": 5209, "protein_name": "E3 ubiquitin-protein ligase rnf213-alpha", "gene_name": "rnf213a", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase rnf213-alpha", "refseq_ac": [ { "id": "NP_001340764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001340764", "type": "external" } ], "gene_names_uniprotkb": "rnf213a; rnf213; wu:fm55d09", "gene_names_refseq": "rnf213a; rnf213; wu:fm55d09", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase rnf213-alpha; 2.3.2.-; 2.3.2.27; 3.6.4.-; E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha; Mysterin-A; Mysterin-alpha; RING finger protein 213-A; RING finger protein 213-alpha", "protein_names_refseq": "E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha; E3 ubiquitin-protein ligase rnf213-alpha; RING finger protein 213-A; RING finger protein 213-alpha; RING-type E3 ubiquitin transferase rnf213-alpha; RNF213 alpha; mysterin-A; mysterin-alpha; protein ALO17; ring finger protein 213", "tax_id": 7955, "disease": "cerebral cavernous malformation (Disease Ontology:DOID:0060669); Moyamoya disease (Disease Ontology:DOID:13099)", "pathway": " (dre:503775); (R-DRE-983168)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "16109975;21799892;23594743;24683187;26530008;27125596;27189481;30705059;32248732", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01020168.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. Sequence Note:., [RefSeq]; Atypical E3 ubiquitin ligase that can catalyze ubiquitination of both proteins and lipids, and which is involved in various processes, such as lipid metabolism, angiogenesis and cell-autonomous immunity (By similarity). Acts as a key immune sensor by catalyzing ubiquitination of the lipid A moiety of bacterial lipopolysaccharide (LPS) via its RZ-type zinc-finger: restricts the proliferation of cytosolic bacteria, such as Salmonella, by generating the bacterial ubiquitin coat through the ubiquitination of LPS (By similarity). Ubiquitination of LPS triggers cell-autonomous immunity, such as antibacterial autophagy, leading to degradation of the microbial invader (By similarity). Involved in lipid metabolism by regulating fat storage and lipid droplet formation; act by inhibiting the lipolytic process (PubMed:30705059). Also regulates lipotoxicity by inhibiting desaturation of fatty acids (By similarity). Also acts as an E3 ubiquitin-protein ligase via its RING-type zinc finger (By similarity). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of proteins downstream of rspo3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (By similarity). Also has ATPase activity; ATPase activity is required for ubiquitination of LPS (By similarity). Also involved in neuromuscular regulation (PubMed:26530008)., [UniProtKB, UniProtKB, PubMed, PubMed]; Mutations of RNF213 are responsible for sporadic cerebral cavernous malformation and lead to a mulberry-like cluster in zebrafish., [RefSeq, PubMed]; Rnf213a mutant zebrafish developed abnormal angiogenesis in intersegmental vessels and cranial secondary vessels. Endothelial cells exhibited the defects in morphogenesis and formation of vascular tubes despite normal cell to cell contacts., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "6.3.2.19", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.19", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005811 lipid droplet;GO:0005829 cytosol", "go_biological_process": "GO:0008015 blood circulation;GO:0019216 regulation of lipid metabolic process;GO:0098792 xenophagy;GO:0042742 defense response to bacterium;GO:0002040 sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IBK5-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBL7-1", "uniprot_id": [ { "id": "HTF4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBL7", "type": "external" } ], "mass": 77512.0, "length": 726, "protein_name": "Transcription factor 12", "gene_name": "tcf12", "organism": "Zebrafish", "refseq_name": "transcription factor 12", "refseq_ac": [ { "id": "NP_999981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999981", "type": "external" } ], "gene_names_uniprotkb": "tcf12; SO:0001217; TCF-12; wu:fb74g05; wu:fc43e06; zgc:110341; zgc:85956", "gene_names_refseq": "TCF-12; tcf12; wu:fb74g05; wu:fc43e06; zgc:110341; zgc:85956", "protein_names_uniprotkb": "Transcription factor 12; TCF-12", "protein_names_refseq": "TF12; transcription factor 12", "tax_id": 7955, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); Pitt-Hopkins syndrome (Disease Ontology:DOID:0060488); craniosynostosis 3 (Disease Ontology:DOID:0061011); hypogonadotropic hypogonadism (Disease Ontology:DOID:0090070); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:407985); (R-DRE-8939236)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "23594743;30375332;32620954", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC070024.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC070024.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci., [RefSeq, PubMed]; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity). May be involved in the functional network that regulates the development of the GnRH axis (PubMed:32620954)., [UniProtKB, PubMed, UniProtKB]; We show that combinatorial loss of TCF12 and TWIST1 homologs in zebrafish also results in specific loss of the coronal suture Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PFS7;E9QDA6;Q6NSM7", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0031175 neuron projection development;GO:0043010 camera-type eye development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IBL7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBM0-1", "uniprot_id": [ { "id": "A0A0R4IBM0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBM0", "type": "external" } ], "mass": 79740.0, "length": 730, "protein_name": "Neuregulin 1; Pro-neuregulin-1, membrane-bound isoform isoform IIb12", "gene_name": "nrg1", "organism": "Zebrafish", "refseq_name": "pro-neuregulin-1, membrane-bound isoform isoform IIb12", "refseq_ac": [ { "id": "NP_001264015", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264015", "type": "external" } ], "gene_names_uniprotkb": "nrg1; wu:fm70e01", "gene_names_refseq": "nrg1; wu:fm70e01", "protein_names_uniprotkb": "Neuregulin 1; Pro-neuregulin-1, membrane-bound isoform isoform IIb12", "protein_names_refseq": "neuregulin 1 type I isoform; neuregulin 1 type II isoform; neuregulin 1 type III isoform; neuregulin1; pro-neuregulin-1, membrane-bound isoform isoform IIb12", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); obstructive sleep apnea (Disease Ontology:DOID:0050848); schizophrenia 6 (Disease Ontology:DOID:0070082); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); Alzheimer's disease (Disease Ontology:DOID:10652); dementia (Disease Ontology:DOID:1307); cerebral malaria (Disease Ontology:DOID:14069); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); cannabis dependence (Disease Ontology:DOID:1849); transient cerebral ischemia (Disease Ontology:DOID:224); ovarian cancer (Disease Ontology:DOID:2394); psychotic disorder (Disease Ontology:DOID:2468); substance abuse (Disease Ontology:DOID:302); bipolar disorder (Disease Ontology:DOID:3312); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); middle cerebral artery infarction (Disease Ontology:DOID:3525); tuberculosis (Disease Ontology:DOID:399); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); cannabis abuse (Disease Ontology:DOID:9505)", "pathway": " (dre:796461); (R-DRE-1227986); (R-DRE-1236394); (R-DRE-1250196); (R-DRE-1250342); (R-DRE-1250347); (R-DRE-1257604); (R-DRE-1358803); (R-DRE-1963640); (R-DRE-1963642); (R-DRE-5673001); (R-DRE-6785631); (R-DRE-6811558); (R-DRE-8847993); (R-DRE-8863795)", "pathway_count": 15, "publication_count": 11, "publication_id_list": "16481353;16873582;18599505;18996920;19133254;23594743;36417527;36513650;36823429;36846912;37484916", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: FJ593488.1, SRR32588719.4060736.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. Transcript Variant: This variant (4) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting protein (isoform IIb12) is longer and has a distinct N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Disc1 and nrg1 function in controlling development of oligodendrocytes and neurones from olig2-expressing precursor cells., [RefSeq, PubMed]; ErbB3 signaling is required for normal migration of trunk, but not cranial, neural crest cells Erratum:[Development. 2008 Sep;135(17):2993], [RefSeq, PubMed]; NRG1 and PI3K functionally interact with ErbB2 and ErbB3 during regeneration, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P469", "ec_number_list": [], "go_molecular_function": "GO:0030296 protein tyrosine kinase activator activity;GO:0008083 growth factor activity;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0048484 enteric nervous system development;GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0007420 brain development;GO:0001755 neural crest cell migration", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IBM0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBM4-1", "uniprot_id": [ { "id": "A0A0R4IBM4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBM4", "type": "external" } ], "mass": 26157.0, "length": 231, "protein_name": "Si:ch73-345f18.3", "gene_name": "si:ch73-345f18.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-345f18.3 isoform X1", "refseq_ac": [ { "id": "XP_002664081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664081", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-345f18.3", "gene_names_refseq": "si:ch73-345f18.3", "protein_names_uniprotkb": "Si:ch73-345f18.3", "protein_names_refseq": "uncharacterized protein si:ch73-345f18.3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334727)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002664081.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RKK0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IBM4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBN4-1", "uniprot_id": [ { "id": "A0A0R4IBN4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBN4", "type": "external" } ], "mass": 56949.0, "length": 510, "protein_name": "UTP--glucose-1-phosphate uridylyltransferase", "gene_name": "ugp2b", "organism": "Zebrafish", "refseq_name": "UDP-glucose pyrophosphorylase 2b isoform X2", "refseq_ac": [ { "id": "XP_005158553", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158553", "type": "external" } ], "gene_names_uniprotkb": "ugp2b; Ugp2; fi53h10; wu:fi53h10; zgc:85662", "gene_names_refseq": "Ugp2; fi53h10; ugp2b; wu:fi53h10; zgc:85662", "protein_names_uniprotkb": "UTP--glucose-1-phosphate uridylyltransferase; 2.7.7.9", "protein_names_refseq": "UDP-glucose pyrophosphorylase 2b isoform X2", "tax_id": 7955, "disease": "developmental and epileptic encephalopathy 83 (Disease Ontology:DOID:0112218); cancer (Disease Ontology:DOID:162)", "pathway": " (dre:334420)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23594743;27189481;28252024;31820119;38803914;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B4X0", "ec_number_list": [ { "id": "2.7.7.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.9", "type": "external" } ], "go_molecular_function": "GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0005978 glycogen biosynthetic process;GO:0006011 UDP-alpha-D-glucose metabolic process;GO:0008345 larval locomotory behavior;GO:0005977 glycogen metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IBN4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBQ5-1", "uniprot_id": [ { "id": "A0A0R4IBQ5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBQ5", "type": "external" } ], "mass": 92647.0, "length": 833, "protein_name": "Protocadherin-20", "gene_name": "pcdh20l", "organism": "Zebrafish", "refseq_name": "protocadherin-20 precursor", "refseq_ac": [ { "id": "NP_001338645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338645", "type": "external" } ], "gene_names_uniprotkb": "pcdh20l; pcdh20; si:dkey-27i16.3", "gene_names_refseq": "pcdh20l; si:dkey-27i16.3", "protein_names_uniprotkb": "Protocadherin-20", "protein_names_refseq": "protocadherin-20 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:568796)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23559552;23594743;32173538", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01013787.1, GFIL01037406.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On May 23, 2017 this sequence version replaced XP_697243.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PAJ2", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IBQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBS8-1", "uniprot_id": [ { "id": "A0A0R4IBS8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBS8", "type": "external" } ], "mass": 54139.0, "length": 469, "protein_name": "Sorting nexin 7; Sorting nexin-7 isoform X1", "gene_name": "snx7", "organism": "Zebrafish", "refseq_name": "sorting nexin-7 isoform X1", "refseq_ac": [ { "id": "XP_005162901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162901", "type": "external" } ], "gene_names_uniprotkb": "snx7; zgc:92458", "gene_names_refseq": "snx7; zgc:92458", "protein_names_uniprotkb": "Sorting nexin 7; Sorting nexin-7 isoform X1", "protein_names_refseq": "sorting nexin-7 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:431776)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22213104;23594743;23897685;31680844", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9U9", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005769 early endosome;GO:0000407 phagophore assembly site;GO:0005737 cytoplasm", "go_biological_process": "GO:0001889 liver development;GO:0015031 protein transport;GO:0043066 negative regulation of apoptotic process;GO:0000423 mitophagy;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IBS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBT0-1", "uniprot_id": [ { "id": "A0A0R4IBT0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBT0", "type": "external" } ], "mass": 70837.0, "length": 663, "protein_name": "Branchpoint-bridging protein", "gene_name": "sf1", "organism": "Zebrafish", "refseq_name": "splicing factor 1 isoform X1", "refseq_ac": [ { "id": "XP_009301350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301350", "type": "external" } ], "gene_names_uniprotkb": "sf1; SF1; wu:fc09f06; znf162", "gene_names_refseq": "sf1; wu:fc09f06; znf162", "protein_names_uniprotkb": "Branchpoint-bridging protein", "protein_names_refseq": "splicing factor 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:572785)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11116086;15520368;15716491;16109975;18307296;23594743;23637638;27156127;27189481;27317806;28575219;30290758;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BAW2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0045131 pre-mRNA branch point binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005681 spliceosomal complex;GO:0005634 nucleus", "go_biological_process": "GO:0060041 retina development in camera-type eye;GO:0000398 mRNA splicing, via spliceosome;GO:0080090 regulation of primary metabolic process;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "A0A0R4IBT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IBX9-1", "uniprot_id": [ { "id": "A0A0R4IBX9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IBX9", "type": "external" } ], "mass": 9647.0, "length": 87, "protein_name": "Non-histone chromosomal protein HMG-like; Si:ch73-1a9.3", "gene_name": "hmgn1b", "organism": "Zebrafish", "refseq_name": "non-histone chromosomal protein HMG-like", "refseq_ac": [ { "id": "NP_001373649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373649", "type": "external" } ], "gene_names_uniprotkb": "hmgn1b; linc-mipep; lnc_rps25; lncrps25; si:ch73-1a9.3", "gene_names_refseq": "hmgn1b; im:7159173; linc-mipep; lnc_rps25; lncrps25; si:ch73-1a9.3", "protein_names_uniprotkb": "Non-histone chromosomal protein HMG-like; Si:ch73-1a9.3", "protein_names_refseq": "TCONS_00009015; non-histone chromosomal protein HMG-17; non-histone chromosomal protein HMG-like", "tax_id": 7955, "disease": "", "pathway": " (dre:556254)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23594743;24705786;27189481;28455512;31549395;37191016", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1227665.1, GFIL01022837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Sep 2, 2020 this sequence version replaced XP_005169261.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGK7", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0031492 nucleosomal DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0007409 axonogenesis;GO:0006325 chromatin organization;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IBX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IC00-1", "uniprot_id": [ { "id": "A0A0R4IC00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IC00", "type": "external" } ], "mass": 93760.0, "length": 853, "protein_name": "Olfactory receptor C family, h1; Olfactory receptor CH1 precursor", "gene_name": "olfch1", "organism": "Zebrafish", "refseq_name": "olfactory receptor CH1", "refseq_ac": [ { "id": "NP_001103760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103760", "type": "external" } ], "gene_names_uniprotkb": "olfch1; si:dkey-245i2.4", "gene_names_refseq": "olfch1; si:dkey-245i2.4", "protein_names_uniprotkb": "Olfactory receptor C family, h1; Olfactory receptor CH1 precursor", "protein_names_refseq": "B01; Dr10-1; olfactory receptor CH1; pheromone receptor-like; putative pheromone receptor; sub 10-1; v2rb1", "tax_id": 7955, "disease": "", "pathway": " (dre:100004933)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.16031221.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Nov 16, 2007 this sequence version replaced XP_001344111.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NGH5", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IC00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IC20-1", "uniprot_id": [ { "id": "A0A0R4IC20_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IC20", "type": "external" } ], "mass": 18522.0, "length": 167, "protein_name": "Si:ch211-276i12.9; Uncharacterized protein LOC103908774", "gene_name": "si:ch211-276i12.9", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC103908774", "refseq_ac": [ { "id": "NP_001373575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373575", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-276i12.9", "gene_names_refseq": "si:ch211-276i12.9", "protein_names_uniprotkb": "Si:ch211-276i12.9; Uncharacterized protein LOC103908774", "protein_names_refseq": "uncharacterized protein LOC103908774", "tax_id": 7955, "disease": "", "pathway": " (dre:103908774)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: EH436639.1, EH563511.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_009289536.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AS92", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IC20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IC31-1", "uniprot_id": [ { "id": "A0A0R4IC31_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IC31", "type": "external" } ], "mass": 172154.0, "length": 1596, "protein_name": "A kinase (PRKA) anchor protein 12b; A-kinase anchor protein 12b isoform 1", "gene_name": "akap12b", "organism": "Zebrafish", "refseq_name": "A-kinase anchor protein 12b isoform 1", "refseq_ac": [ { "id": "NP_001268717", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268717", "type": "external" } ], "gene_names_uniprotkb": "akap12b; akap12; cb27; esr1; fb72g12; id:ibd1202; sb:cb27; si:ch73-192g21.1; wu:fb72g12; wu:fc21c03", "gene_names_refseq": "akap12b; akap12; cb27; esr1; fb72g12; id:ibd1202; sb:cb27; si:ch73-192g21.1; wu:fb72g12; wu:fc21c03", "protein_names_uniprotkb": "A kinase (PRKA) anchor protein 12b; A-kinase anchor protein 12b isoform 1", "protein_names_refseq": "A kinase (PRKA) anchor protein (gravin) 12b; A kinase (PRKA) anchor protein (gravin) 12; A-kinase anchor protein 12b isoform 1; gravin", "tax_id": 7955, "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); colorectal carcinoma (Disease Ontology:DOID:0080199); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (dre:567365); (R-DRE-9035034)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "17575056;18725198;22192928;23594743;25534553;26700682;28252024;28855284;31383248", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01000772.1, SRR26395062.409196.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB766946.1 and JBMGRA010000020.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Gravin is required for the conversion of mesodermal cells from a highly migratory behavior to the medio-laterally intercalative behavior required for body axis extension., [RefSeq, PubMed]; Loss of akap12 function causes severe defects in locomotor activity in zebrafish embryos., [RefSeq, PubMed]; The findings provide the first experimental evidence that akap12beta regulates heart laterality via cadherin1., [RefSeq, PubMed]; These results provide an important step forward in understanding the mechanism of Gravin function in cell shape regulation and provide valuable insight into how Gravin acts as a cytoskeletal regulator., [RefSeq, PubMed]; Zebrafish embryos depleted of akap12 (akap12 morphants) exhibited severe hemorrhages., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4X8", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0051018 protein kinase A binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0010739 positive regulation of protein kinase A signaling;GO:0000902 cell morphogenesis;GO:0009887 animal organ morphogenesis;GO:0010738 regulation of protein kinase A signaling", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IC31-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IC37-1", "uniprot_id": [ { "id": "CPSF1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IC37", "type": "external" } ], "mass": 163195.0, "length": 1451, "protein_name": "Cleavage and polyadenylation specificity factor subunit 1", "gene_name": "cpsf1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cpsf1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 1; Cleavage and polyadenylation specific factor 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-73856); (R-DRE-77595); (R-DRE-9770562)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;30689892", "class_list": "", "function": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). Plays a role in eye morphogenesis and the development of retinal ganglion cell projections to the tectum (PubMed:30689892)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IC37-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICA2-1", "uniprot_id": [ { "id": "A0A0R4ICA2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICA2", "type": "external" } ], "mass": 104492.0, "length": 939, "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "toporsb", "organism": "Zebrafish", "refseq_name": "uncharacterized protein toporsb isoform X1", "refseq_ac": [ { "id": "XP_003201680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201680", "type": "external" } ], "gene_names_uniprotkb": "toporsb", "gene_names_refseq": "toporsb", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Topors; 2.3.2.27; RING-type E3 ubiquitin transferase Topors; SUMO1-protein E3 ligase Topors; Topoisomerase I-binding RING finger protein; Topoisomerase I-binding arginine/serine-rich protein; Tumor suppressor p53-binding protein 3", "protein_names_refseq": "uncharacterized protein toporsb isoform X1", "tax_id": 7955, "disease": "retinitis pigmentosa 31 (Disease Ontology:DOID:0110391)", "pathway": " (dre:796087)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RPD6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0032391 photoreceptor connecting cilium", "go_biological_process": "GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000209 protein polyubiquitination;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICA2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICA5-1", "uniprot_id": [ { "id": "A0A0R4ICA5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICA5", "type": "external" } ], "mass": 63338.0, "length": 578, "protein_name": "Solute carrier family 15 member 4", "gene_name": "slc15a4", "organism": "Zebrafish", "refseq_name": "solute carrier family 15 member 4", "refseq_ac": [ { "id": "NP_001307458", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307458", "type": "external" } ], "gene_names_uniprotkb": "slc15a4; bZ1L10.1; zgc:56484; zgc:63767", "gene_names_refseq": "bZ1L10.1; slc15a4; zgc:56484; zgc:63767", "protein_names_uniprotkb": "Solute carrier family 15 member 4", "protein_names_refseq": "bZ1L10.1 (novel peptide transporter); solute carrier family 15 (oligopeptide transporter), member 4; solute carrier family 15 member 4", "tax_id": 7955, "disease": "", "pathway": " (dre:393932); (R-DRE-427975); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;28694436", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01038254.1, GDQQ01004094.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Feb 27, 2016 this sequence version replaced XP_005167300.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and orthologous alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8Q5", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity;GO:0005290 L-histidine transmembrane transporter activity;GO:0071916 dipeptide transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0005765 lysosomal membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0045087 innate immune response;GO:0140206 dipeptide import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ICA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICC1-1", "uniprot_id": [ { "id": "A0A0R4ICC1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICC1", "type": "external" } ], "mass": 82033.0, "length": 728, "protein_name": "Twinkle mtDNA helicase", "gene_name": "twnk", "organism": "Zebrafish", "refseq_name": "twinkle mtDNA helicase", "refseq_ac": [ { "id": "NP_001264527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264527", "type": "external" } ], "gene_names_uniprotkb": "twnk; fi04d09; peo1; wu:fi04d09", "gene_names_refseq": "fi04d09; peo1; twnk; wu:fi04d09", "protein_names_uniprotkb": "Twinkle mtDNA helicase; 5.6.2.3; Twinkle protein, mitochondrial", "protein_names_refseq": "progressive external ophthalmoplegia 1; twinkle mtDNA helicase; twinkle protein, mitochondrial-like", "tax_id": 7955, "disease": "Perrault syndrome (Disease Ontology:DOID:0050857); mitochondrial DNA depletion syndrome (Disease Ontology:DOID:0070329); mitochondrial DNA depletion syndrome 7 (Disease Ontology:DOID:0080126); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5 (Disease Ontology:DOID:0111518); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3 (Disease Ontology:DOID:0111520); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dre:100330448); (R-DRE-9837999); (R-DRE-9913635)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "18335061;22465854;23516612;23594743;25771346;27189481;27924917;28535465;32806454", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01006689.1, SRR26395014.1082722.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1 and EV561328.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Mitochondrial helicase involved in mtDNA replication and repair. Might have a role in mtDNA repair. Has DNA strand separation activity needed to form a processive replication fork for leading strand synthesis which is catalyzed by the formation of a replisome complex with POLG and mtSDB. Preferentially unwinds DNA substrates with pre-existing 5'-and 3'- single-stranded tails but is also active on a 5'- flap substrate. Can dissociate the invading strand of immobile or mobile D-loop DNA structures irrespective of the single strand polarity of the third strand. In addition to its DNA strand separation activity, also has DNA strand annealing, DNA strand-exchange and DNA branch migration activities., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P494", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "5.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0008289 lipid binding;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0006264 mitochondrial DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4ICC1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICG0-1", "uniprot_id": [ { "id": "A0A0R4ICG0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICG0", "type": "external" } ], "mass": 149844.0, "length": 1387, "protein_name": "Period circadian clock 1a; Period circadian protein homolog 1a isoform X1", "gene_name": "per1a", "organism": "Zebrafish", "refseq_name": "period circadian protein homolog 1a isoform X1", "refseq_ac": [ { "id": "XP_005172682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172682", "type": "external" } ], "gene_names_uniprotkb": "per1a; per1; si:ch211-237l4.4; zC237L4.4", "gene_names_refseq": "per1a; per1; si:ch211-237l4.4; zC237L4.4", "protein_names_uniprotkb": "Period circadian clock 1a; Period circadian protein homolog 1a isoform X1", "protein_names_refseq": "period circadian protein homolog 1a isoform X1", "tax_id": 7955, "disease": "attention deficit hyperactivity disorder (Disease Ontology:DOID:1094)", "pathway": " (dre:563926)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11517315;12001265;12111534;14653994;17785416;23594743;34329618;34769181;34925060;35233929;37075492", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJV3", "ec_number_list": [], "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0001222 transcription corepressor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042542 response to hydrogen peroxide;GO:0032922 circadian regulation of gene expression;GO:0043153 entrainment of circadian clock by photoperiod;GO:0009648 photoperiodism", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4ICG0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICG8-1", "uniprot_id": [ { "id": "A0A0R4ICG8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICG8", "type": "external" } ], "mass": 15519.0, "length": 134, "protein_name": "Coiled-coil domain-containing protein 18; Si:ch73-389b16.1", "gene_name": "si:ch73-389b16.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-389b16.1", "refseq_ac": [ { "id": "XP_002662467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662467", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-389b16.1", "gene_names_refseq": "si:ch73-389b16.1", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 18; Si:ch73-389b16.1", "protein_names_refseq": "uncharacterized protein si:ch73-389b16.1", "tax_id": 7955, "disease": "", "pathway": " (dre:100331788)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RR00", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICG8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICH7-1", "uniprot_id": [ { "id": "A0A0R4ICH7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICH7", "type": "external" } ], "mass": 71172.0, "length": 647, "protein_name": "Cardiomyopathy-associated protein 5; Si:ch1073-398f15.1", "gene_name": "si:ch1073-398f15.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch1073-398f15.1", "refseq_ac": [ { "id": "XP_005170298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170298", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-398f15.1", "gene_names_refseq": "si:ch1073-398f15.1", "protein_names_uniprotkb": "Cardiomyopathy-associated protein 5; Si:ch1073-398f15.1", "protein_names_refseq": "uncharacterized protein si:ch1073-398f15.1", "tax_id": 7955, "disease": "", "pathway": " (dre:101884664)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BHN2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICH9-1", "uniprot_id": [ { "id": "A0A0R4ICH9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICH9", "type": "external" } ], "mass": 49954.0, "length": 437, "protein_name": "ATP-sensitive inward rectifier potassium channel 12; Potassium inwardly rectifying channel subfamily J member 12a", "gene_name": "kcnj12a", "organism": "Zebrafish", "refseq_name": "ATP-sensitive inward rectifier potassium channel 12", "refseq_ac": [ { "id": "XP_005162964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162964", "type": "external" } ], "gene_names_uniprotkb": "kcnj12a", "gene_names_refseq": "kcnj12a", "protein_names_uniprotkb": "ATP-sensitive inward rectifier potassium channel 12; Potassium inwardly rectifying channel subfamily J member 12a", "protein_names_refseq": "ATP-sensitive inward rectifier potassium channel 12", "tax_id": 7955, "disease": "", "pathway": " (dre:569146); (R-DRE-1296053); (R-DRE-5576886)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9Y4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0007399 nervous system development;GO:0034765 regulation of monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICI5-1", "uniprot_id": [ { "id": "A0A0R4ICI5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICI5", "type": "external" } ], "mass": 68762.0, "length": 612, "protein_name": "RNA polymerase I-specific transcription initiation factor RRN3; RRN3 homolog, RNA polymerase I transcription factor", "gene_name": "rrn3", "organism": "Zebrafish", "refseq_name": "RNA polymerase I-specific transcription initiation factor RRN3", "refseq_ac": [ { "id": "XP_005164166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164166", "type": "external" } ], "gene_names_uniprotkb": "rrn3", "gene_names_refseq": "rrn3", "protein_names_uniprotkb": "RNA polymerase I-specific transcription initiation factor RRN3; RRN3 homolog, RNA polymerase I transcription factor", "protein_names_refseq": "RNA polymerase I-specific transcription initiation factor RRN3", "tax_id": 7955, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dre:558718); (R-DRE-73762); (R-DRE-73772)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UW46", "ec_number_list": [], "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0001181 RNA polymerase I general transcription initiation factor activity;GO:0001042 RNA polymerase I core binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006361 transcription initiation at RNA polymerase I promoter", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICI5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICJ7-1", "uniprot_id": [ { "id": "A0A0R4ICJ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICJ7", "type": "external" } ], "mass": 40525.0, "length": 353, "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "b4galt4", "organism": "Zebrafish", "refseq_name": "beta-1,4-galactosyltransferase 4", "refseq_ac": [ { "id": "NP_001007402", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007402", "type": "external" } ], "gene_names_uniprotkb": "b4galt4; CH1073-177A15.1; wu:fb08f09; zgc:101780", "gene_names_refseq": "CH1073-177A15.1; b4galt4; wu:fb08f09; zgc:101780", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase; 2.4.1.-; Beta-1,4-GalTase", "protein_names_refseq": "beta-1,4-galactosyltransferase 4", "tax_id": 7955, "disease": "", "pathway": " (dre:492760); (R-DRE-2022854); (R-DRE-975577)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588720.145178.1, SRR32588714.15580721.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Oct 18, 2018 this sequence version replaced NP_001007402.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BA11", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.274", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.274", "type": "external" } ], "go_molecular_function": "GO:0008378 galactosyltransferase activity;GO:0046872 metal ion binding;GO:0003945 N-acetyllactosamine synthase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ICJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICK0-1", "uniprot_id": [ { "id": "A0A0R4ICK0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICK0", "type": "external" } ], "mass": 24597.0, "length": 226, "protein_name": "Complement C1q-like protein 4; Si:dkeyp-110c7.4", "gene_name": "si:dkeyp-110c7.4", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:dkeyp-110c7.4", "gene_names_refseq": "", "protein_names_uniprotkb": "Complement C1q-like protein 4; Si:dkeyp-110c7.4", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:568625)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T8E7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0045202 synapse", "go_biological_process": "GO:0099558 maintenance of synapse structure", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICK5-1", "uniprot_id": [ { "id": "A0A0R4ICK5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICK5", "type": "external" } ], "mass": 19359.0, "length": 174, "protein_name": "Ensconsin; Si:ch73-281i18.3", "gene_name": "si:ch73-281i18.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-281i18.3 isoform X2", "refseq_ac": [ { "id": "XP_002661057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661057", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-281i18.3", "gene_names_refseq": "si:ch73-281i18.3", "protein_names_uniprotkb": "Ensconsin; Si:ch73-281i18.3", "protein_names_refseq": "uncharacterized protein si:ch73-281i18.3 isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:100330519)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RQU3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICK5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICL0-1", "uniprot_id": [ { "id": "A0A0R4ICL0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICL0", "type": "external" } ], "mass": 163186.0, "length": 1476, "protein_name": "Family with sequence similarity 193 member A; Protein FAM193A", "gene_name": "fam193a", "organism": "Zebrafish", "refseq_name": "protein FAM193A", "refseq_ac": [ { "id": "NP_001315324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315324", "type": "external" } ], "gene_names_uniprotkb": "fam193a; im:7155132", "gene_names_refseq": "fam193a; im:7155132", "protein_names_uniprotkb": "Family with sequence similarity 193 member A; Protein FAM193A", "protein_names_refseq": "protein FAM193A", "tax_id": 7955, "disease": "", "pathway": " (dre:564207)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01010192.1, GDQH01007393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476731, SAMEA4476734 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 25, 2025 this sequence version replaced NP_001315324.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4R5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ICL0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICM6-1", "uniprot_id": [ { "id": "A0A0R4ICM6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICM6", "type": "external" } ], "mass": 173179.0, "length": 1578, "protein_name": "Mitogen-activated protein kinase-binding protein 1", "gene_name": "mapkbp1", "organism": "Zebrafish", "refseq_name": "mitogen-activated protein kinase-binding protein 1 isoform X5", "refseq_ac": [ { "id": "XP_009291133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291133", "type": "external" } ], "gene_names_uniprotkb": "mapkbp1", "gene_names_refseq": "mapkbp1", "protein_names_uniprotkb": "Mitogen-activated protein kinase-binding protein 1", "protein_names_refseq": "mitogen-activated protein kinase-binding protein 1 isoform X5", "tax_id": 7955, "disease": "nephronophthisis 20 (Disease Ontology:DOID:0111127)", "pathway": " (dre:100535386)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AR60", "ec_number_list": [], "go_molecular_function": "GO:0016301 kinase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046330 positive regulation of JNK cascade;GO:0043124 negative regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICM6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICN6-1", "uniprot_id": [ { "id": "A0A0R4ICN6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICN6", "type": "external" } ], "mass": 99066.0, "length": 922, "protein_name": "Family with sequence similarity 193 member B; Protein FAM193B", "gene_name": "fam193b", "organism": "Zebrafish", "refseq_name": "protein FAM193B", "refseq_ac": [ { "id": "XP_697699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697699", "type": "external" } ], "gene_names_uniprotkb": "fam193b", "gene_names_refseq": "fam193b", "protein_names_uniprotkb": "Family with sequence similarity 193 member B; Protein FAM193B", "protein_names_refseq": "protein FAM193B", "tax_id": 7955, "disease": "", "pathway": " (dre:569234)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_697699.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TE05", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICN6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICP4-1", "uniprot_id": [ { "id": "A0A0R4ICP4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICP4", "type": "external" } ], "mass": 19790.0, "length": 177, "protein_name": "Si:ch73-347e22.8; Tropomyosin", "gene_name": "si:ch73-347e22.8", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-347e22.8", "refseq_ac": [ { "id": "XP_005173816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173816", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-347e22.8", "gene_names_refseq": "si:ch73-347e22.8", "protein_names_uniprotkb": "Si:ch73-347e22.8; Tropomyosin", "protein_names_refseq": "uncharacterized protein si:ch73-347e22.8", "tax_id": 7955, "disease": "", "pathway": " (dre:100000389)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BL41", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICP4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICP9-1", "uniprot_id": [ { "id": "A0A0R4ICP9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICP9", "type": "external" } ], "mass": 13498.0, "length": 120, "protein_name": "Protein FAM174C precursor; Si:ch211-262i1.6", "gene_name": "fam174c", "organism": "Zebrafish", "refseq_name": "protein FAM174C precursor", "refseq_ac": [ { "id": "NP_001295480", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295480", "type": "external" } ], "gene_names_uniprotkb": "fam174c; fi40b06; si:ch211-262i1.6; wu:fd58f02; wu:fi40b06", "gene_names_refseq": "fam174c; fi40b06; si:ch211-262i1.6; wu:fd58f02; wu:fi40b06", "protein_names_uniprotkb": "Protein FAM174C precursor; Si:ch211-262i1.6", "protein_names_refseq": "protein FAM174C precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:334310)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01004614.1, GDQH01006391.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1, DN771102.1 and EH512740.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7H7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ICP9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICQ4-1", "uniprot_id": [ { "id": "A0A0R4ICQ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICQ4", "type": "external" } ], "mass": 37360.0, "length": 325, "protein_name": "Gastrula zinc finger protein XlCGF57.1-like; Gastrula zinc finger protein XlCGF8.2DB-like; Si:ch211-212k5.4", "gene_name": "si:ch211-212k5.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-212k5.4", "refseq_ac": [ { "id": "XP_017211232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211232", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-212k5.4", "gene_names_refseq": "si:ch211-212k5.4", "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF57.1-like; Gastrula zinc finger protein XlCGF8.2DB-like; Si:ch211-212k5.4", "protein_names_refseq": "uncharacterized protein si:ch211-212k5.4", "tax_id": 7955, "disease": "", "pathway": " (dre:108183932)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z083", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICQ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICR1-1", "uniprot_id": [ { "id": "A0A0R4ICR1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICR1", "type": "external" } ], "mass": 62898.0, "length": 570, "protein_name": "Nectin cell adhesion molecule 4b; Nectin-4", "gene_name": "nectin4b", "organism": "Zebrafish", "refseq_name": "nectin-4", "refseq_ac": [ { "id": "XP_001334985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334985", "type": "external" } ], "gene_names_uniprotkb": "nectin4b", "gene_names_refseq": "nectin4b", "protein_names_uniprotkb": "Nectin cell adhesion molecule 4b; Nectin-4", "protein_names_refseq": "nectin-4", "tax_id": 7955, "disease": "", "pathway": " (dre:794920); (R-DRE-418990); (R-DRE-420597)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_001334985.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PUD3", "ec_number_list": [], "go_molecular_function": "GO:0098631 cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICR8-1", "uniprot_id": [ { "id": "A0A0R4ICR8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICR8", "type": "external" } ], "mass": 43957.0, "length": 392, "protein_name": "Basigin", "gene_name": "bsg", "organism": "Zebrafish", "refseq_name": "basigin isoform 1 precursor", "refseq_ac": [ { "id": "NP_937785", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_937785", "type": "external" } ], "gene_names_uniprotkb": "bsg; wu:fb26a05; wu:fo98e12", "gene_names_refseq": "bsg; wu:fb26a05; wu:fo98e12", "protein_names_uniprotkb": "Basigin", "protein_names_refseq": "5A11/Basigin-2; basigin isoform 1 precursor; cd147", "tax_id": 7955, "disease": "transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial carcinoma (Disease Ontology:DOID:2871); breast ductal carcinoma (Disease Ontology:DOID:3007); lung squamous cell carcinoma (Disease Ontology:DOID:3907); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); ovary serous adenocarcinoma (Disease Ontology:DOID:5744)", "pathway": " (dre:337692); (R-DRE-1474228); (R-DRE-210991); (R-DRE-216083); (R-DRE-433692); (R-DRE-9749641)", "pathway_count": 6, "publication_count": 12, "publication_id_list": "12939332;15520368;16109975;21729873;23594743;25840431;26908177;27294876;28252024;31468037;34046029;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.407213.1, SRR26395062.363575.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1, DT058336.1, EH536274.1, CK356411.1, EH563077.1 and EH520368.1. On Aug 20, 2015 this sequence version replaced NP_937785.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 7, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PDN1", "ec_number_list": [], "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0030424 axon;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411 axon guidance;GO:0070593 dendrite self-avoidance", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0R4ICR8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICS1-1", "uniprot_id": [ { "id": "A0A0R4ICS1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICS1", "type": "external" } ], "mass": 113228.0, "length": 1018, "protein_name": "Integrin alpha-4", "gene_name": "itga4", "organism": "Zebrafish", "refseq_name": "integrin alpha-4 isoform X1", "refseq_ac": [ { "id": "XP_068079775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079775", "type": "external" } ], "gene_names_uniprotkb": "itga4", "gene_names_refseq": "itga4", "protein_names_uniprotkb": "Integrin alpha-4", "protein_names_refseq": "integrin alpha-4 isoform X1", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); intellectual disability (Disease Ontology:DOID:1059); pre-eclampsia (Disease Ontology:DOID:10591); nephritis (Disease Ontology:DOID:10952); pancreatic cancer (Disease Ontology:DOID:1793); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); pneumonia (Disease Ontology:DOID:552); diabetic retinopathy (Disease Ontology:DOID:8947)", "pathway": " (dre:100331333); (R-DRE-198933); (R-DRE-202733); (R-DRE-216083)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AWB6", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0034668 integrin alpha4-beta1 complex;GO:0034669 integrin alpha4-beta7 complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0098609 cell-cell adhesion;GO:0001568 blood vessel development;GO:0043114 regulation of vascular permeability;GO:0060956 endocardial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICS1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICX4-1", "uniprot_id": [ { "id": "A0A0R4ICX4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICX4", "type": "external" } ], "mass": 22787.0, "length": 193, "protein_name": "Regulator of G-protein signaling 21; Si:ch211-117l17.6", "gene_name": "si:ch211-117l17.6", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:ch211-117l17.6", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulator of G-protein signaling 21; Si:ch211-117l17.6", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100151245); (R-DRE-416476); (R-DRE-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PK79", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICY6-1", "uniprot_id": [ { "id": "A0A0R4ICY6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICY6", "type": "external" } ], "mass": 35613.0, "length": 316, "protein_name": "Uncharacterized protein LOC555931; Zgc:171686", "gene_name": "zgc:171686", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC555931 precursor", "refseq_ac": [ { "id": "NP_001104623", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104623", "type": "external" } ], "gene_names_uniprotkb": "zgc:171686", "gene_names_refseq": "zgc:171686", "protein_names_uniprotkb": "Uncharacterized protein LOC555931; Zgc:171686", "protein_names_refseq": "SLAM family member; uncharacterized protein LOC555931 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:555931)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC153995.1, SRR32588728.22447609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Aug 19, 2010 this sequence version replaced NP_001104623.1. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFJ0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ICY6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICZ3-1", "uniprot_id": [ { "id": "A0A0R4ICZ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICZ3", "type": "external" } ], "mass": 88588.0, "length": 796, "protein_name": "Enhancer of polycomb homolog", "gene_name": "epc1a", "organism": "Zebrafish", "refseq_name": "enhancer of polycomb homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_695062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695062", "type": "external" } ], "gene_names_uniprotkb": "epc1a", "gene_names_refseq": "epc1a", "protein_names_uniprotkb": "Enhancer of polycomb homolog", "protein_names_refseq": "enhancer of polycomb homolog 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_695062.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T863", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0032777 piccolo histone acetyltransferase complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ICZ3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ICZ4-1", "uniprot_id": [ { "id": "A0A0R4ICZ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ICZ4", "type": "external" } ], "mass": 21284.0, "length": 208, "protein_name": "Si:ch73-359m17.9; Uncharacterized protein LOC100000433 precursor", "gene_name": "si:ch73-359m17.9", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100000433 precursor", "refseq_ac": [ { "id": "NP_001229574", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229574", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-359m17.9", "gene_names_refseq": "si:ch73-359m17.9", "protein_names_uniprotkb": "Si:ch73-359m17.9; Uncharacterized protein LOC100000433 precursor", "protein_names_refseq": "uncharacterized protein LOC100000433 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100000433)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH492515.1, BC121723.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Jun 19, 2011 this sequence version replaced XP_002665658.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1Y1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ICZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ID09-1", "uniprot_id": [ { "id": "A0A0R4ID09_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ID09", "type": "external" } ], "mass": 82670.0, "length": 733, "protein_name": "Ribosomal protein S6 kinase", "gene_name": "rps6ka3a", "organism": "Zebrafish", "refseq_name": "ribosomal protein S6 kinase alpha-1 isoform X1", "refseq_ac": [ { "id": "XP_005165175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165175", "type": "external" } ], "gene_names_uniprotkb": "rps6ka3a; id:ibd1103; rps6ka3; si:ch211-114c12.12; wu:fk86e02; zgc:56006", "gene_names_refseq": "id:ibd1103; rps6ka3a; rps6ka3; si:ch211-114c12.12; wu:fk86e02; zgc:56006", "protein_names_uniprotkb": "Ribosomal protein S6 kinase; 2.7.11.1", "protein_names_refseq": "ribosomal protein S6 kinase alpha-1 isoform X1", "tax_id": 7955, "disease": "non-syndromic X-linked intellectual disability 19 (Disease Ontology:DOID:0112019); intellectual disability (Disease Ontology:DOID:1059); Coffin-Lowry syndrome (Disease Ontology:DOID:3783)", "pathway": " (dre:338219); (R-DRE-198753); (R-DRE-199920); (R-DRE-2559582); (R-DRE-442742); (R-DRE-444257); (R-DRE-881907)", "pathway_count": 7, "publication_count": 10, "publication_id_list": "11731487;16109975;16517001;17222402;18550893;19500364;23594743;24240475;28252024;34165081", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BCC5", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004711 ribosomal protein S6 kinase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0043588 skin development;GO:0038202 TORC1 signaling;GO:0048565 digestive tract development;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0R4ID09-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ID68-1", "uniprot_id": [ { "id": "A0A0R4ID68_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ID68", "type": "external" } ], "mass": 85020.0, "length": 779, "protein_name": "ATP-dependent 6-phosphofructokinase", "gene_name": "pfklb", "organism": "Zebrafish", "refseq_name": "phosphofructokinase, liver b", "refseq_ac": [ { "id": "NP_001315318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315318", "type": "external" } ], "gene_names_uniprotkb": "pfklb; zgc:110298", "gene_names_refseq": "pfklb; zgc:110298", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase; 2.7.1.11; ATP-PFK; Phosphofructokinase; Phosphohexokinase", "protein_names_refseq": "phosphofructokinase, liver b", "tax_id": 7955, "disease": "", "pathway": " (dre:550259); (R-DRE-6798695); (R-DRE-70171)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "23341543;23594743;27292639;28005350;28102299;28217809;32818036;34278746;35685883;36408747;36535130", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01024352.1, SRR32588715.755871.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 16, 2016 this sequence version replaced XP_009304613.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3T0", "ec_number_list": [ { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.4.17.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.3", "type": "external" }, { "id": "3.1.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "5.3.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.2.1", "type": "external" }, { "id": "5.3.3.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.12", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.1.6.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.14", "type": "external" }, { "id": "3.4.22.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.27", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "4.1.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.4", "type": "external" }, { "id": "3.4.21.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.46", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" }, { "id": "3.5.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.23", "type": "external" }, { "id": "3.4.22.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.1", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.24.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.35", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "3.4.22.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.52", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" } ], "go_molecular_function": "GO:0070095 fructose-6-phosphate binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003872 6-phosphofructokinase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005945 6-phosphofructokinase complex", "go_biological_process": "GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4ID68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ID76-1", "uniprot_id": [ { "id": "A0A0R4ID76_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ID76", "type": "external" } ], "mass": 29727.0, "length": 263, "protein_name": "CD79b molecule, immunoglobulin-associated beta; Uncharacterized protein cd79b", "gene_name": "cd79b", "organism": "Zebrafish", "refseq_name": "uncharacterized protein cd79b isoform X1", "refseq_ac": [ { "id": "XP_021335890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335890", "type": "external" } ], "gene_names_uniprotkb": "cd79b", "gene_names_refseq": "cd79b", "protein_names_uniprotkb": "CD79b molecule, immunoglobulin-associated beta; Uncharacterized protein cd79b", "protein_names_refseq": "uncharacterized protein cd79b isoform X1", "tax_id": 7955, "disease": "diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); mantle cell lymphoma (Disease Ontology:DOID:0050746); splenic marginal zone lymphoma (Disease Ontology:DOID:0050750); follicular lymphoma (Disease Ontology:DOID:0050873); non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); agammaglobulinemia 6 (Disease Ontology:DOID:0081138); chronic lymphocytic leukemia (Disease Ontology:DOID:1040); central nervous system lymphoma (Disease Ontology:DOID:3234); Burkitt lymphoma (Disease Ontology:DOID:8584); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dre:100329481)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QMR2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0019815 B cell receptor complex", "go_biological_process": "GO:0050853 B cell receptor signaling pathway;GO:0030183 B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ID76-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ID77-1", "uniprot_id": [ { "id": "A0A0R4ID77_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ID77", "type": "external" } ], "mass": 99442.0, "length": 968, "protein_name": "Uncharacterized protein LOC556628 precursor; Zgc:111868", "gene_name": "wu:fd14f12", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC556628 precursor", "refseq_ac": [ { "id": "NP_001410464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410464", "type": "external" } ], "gene_names_uniprotkb": "wu:fd14f12; fd14f12; si:ch73-207h17.1; zgc:111868", "gene_names_refseq": "fd14f12; si:ch73-207h17.1; wu:fd14f12; zgc:111868", "protein_names_uniprotkb": "Uncharacterized protein LOC556628 precursor; Zgc:111868", "protein_names_refseq": "uncharacterized protein LOC556628 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:556628)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.500572.1, SRR26395063.981679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jul 28, 2023 this sequence version replaced XP_005156475.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B2I6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ID77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ID81-1", "uniprot_id": [ { "id": "A0A0R4ID81_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ID81", "type": "external" } ], "mass": 53796.0, "length": 478, "protein_name": "Rab11 family-interacting protein 2", "gene_name": "rab11fip2", "organism": "Zebrafish", "refseq_name": "rab11 family-interacting protein 2 isoform X1", "refseq_ac": [ { "id": "XP_009305544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305544", "type": "external" } ], "gene_names_uniprotkb": "rab11fip2", "gene_names_refseq": "rab11fip2", "protein_names_uniprotkb": "Rab11 family-interacting protein 2", "protein_names_refseq": "rab11 family-interacting protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334729)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B7Z5", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005768 endosome;GO:0055038 recycling endosome membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0015031 protein transport;GO:0045055 regulated exocytosis;GO:0001755 neural crest cell migration;GO:0007154 cell communication;GO:0023052 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ID81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ID82-1", "uniprot_id": [ { "id": "A0A0R4ID82_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ID82", "type": "external" } ], "mass": 68103.0, "length": 599, "protein_name": "Vacuolar protein sorting-associated protein 33A", "gene_name": "vps33a", "organism": "Zebrafish", "refseq_name": "vacuolar protein sorting-associated protein 33A", "refseq_ac": [ { "id": "NP_001093443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093443", "type": "external" } ], "gene_names_uniprotkb": "vps33a; im:7136893; wu:fc08g01; wu:fc26c10", "gene_names_refseq": "im:7136893; vps33a; wu:fc08g01; wu:fc26c10", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 33A", "protein_names_refseq": "vacuolar protein sorting 33 homolog A; vacuolar protein sorting 33A; vacuolar protein sorting-associated protein 33A", "tax_id": 7955, "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dre:448942)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16284120;23594743;23639161;28252024;31495570", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095344.1, GDQH01008230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jul 26, 2007 this sequence version replaced XP_683201.2., [RefSeq]; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS16 but not VIPAS39. The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NDX2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005769 early endosome;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4ID82-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDA9-1", "uniprot_id": [ { "id": "A0A0R4IDA9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDA9", "type": "external" } ], "mass": 14234.0, "length": 134, "protein_name": "Si:ch211-113d22.2", "gene_name": "si:ch211-113d22.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-113d22.2 isoform X1", "refseq_ac": [ { "id": "XP_002663578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663578", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-113d22.2", "gene_names_refseq": "si:ch211-113d22.2", "protein_names_uniprotkb": "Si:ch211-113d22.2", "protein_names_refseq": "uncharacterized protein si:ch211-113d22.2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:565641)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDT2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDC4-1", "uniprot_id": [ { "id": "A0A0R4IDC4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDC4", "type": "external" } ], "mass": 8149.0, "length": 73, "protein_name": "Si:ch211-195b11.3; Uncharacterized protein LOC100334344 precursor", "gene_name": "si:ch211-195b11.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100334344 precursor", "refseq_ac": [ { "id": "NP_001278829", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278829", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-195b11.3", "gene_names_refseq": "si:ch211-195b11.3", "protein_names_uniprotkb": "Si:ch211-195b11.3; Uncharacterized protein LOC100334344 precursor", "protein_names_refseq": "pancreatic secretory trypsin inhibitor-like; uncharacterized protein LOC100334344 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100334344)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;23594743;32528955", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH451329.1, EH452886.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB842398.1, EB769236.1, EB766055.1 and EH441449.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P0S0", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IDC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDC9-1", "uniprot_id": [ { "id": "A0A0R4IDC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDC9", "type": "external" } ], "mass": 31324.0, "length": 289, "protein_name": "CXXC-type zinc finger protein 4", "gene_name": "cxxc4", "organism": "Zebrafish", "refseq_name": "CXXC-type zinc finger protein 4", "refseq_ac": [ { "id": "XP_001345418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345418", "type": "external" } ], "gene_names_uniprotkb": "cxxc4", "gene_names_refseq": "cxxc4", "protein_names_uniprotkb": "CXXC-type zinc finger protein 4", "protein_names_refseq": "CXXC-type zinc finger protein 4", "tax_id": 7955, "disease": "", "pathway": " (dre:100006754)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001345418.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q7Z2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDF2-1", "uniprot_id": [ { "id": "A0A0R4IDF2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDF2", "type": "external" } ], "mass": 26151.0, "length": 223, "protein_name": "Si:ch1073-67j19.1; Uncharacterized protein LOC100332348 precursor", "gene_name": "teni.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100332348 precursor", "refseq_ac": [ { "id": "NP_001314821", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314821", "type": "external" } ], "gene_names_uniprotkb": "teni.1; si:ch1073-67j19.1", "gene_names_refseq": "si:ch1073-67j19.1; teni.1", "protein_names_uniprotkb": "Si:ch1073-67j19.1; Uncharacterized protein LOC100332348 precursor", "protein_names_refseq": "uncharacterized protein LOC100332348 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100332348)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;36639393", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01018054.1, SRR32588727.3328961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196788 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On May 27, 2016 this sequence version replaced XP_009298356.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P360", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IDF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDF5-1", "uniprot_id": [ { "id": "A0A0R4IDF5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDF5", "type": "external" } ], "mass": 43556.0, "length": 388, "protein_name": "Si:rp71-36a1.2", "gene_name": "si:rp71-36a1.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:rp71-36a1.2", "refseq_ac": [ { "id": "XP_003201020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201020", "type": "external" } ], "gene_names_uniprotkb": "si:rp71-36a1.2", "gene_names_refseq": "si:rp71-36a1.2", "protein_names_uniprotkb": "Si:rp71-36a1.2", "protein_names_refseq": "uncharacterized protein si:rp71-36a1.2", "tax_id": 7955, "disease": "", "pathway": " (dre:100034566)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003201020.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFS8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDJ7-1", "uniprot_id": [ { "id": "A0A0R4IDJ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDJ7", "type": "external" } ], "mass": 25671.0, "length": 228, "protein_name": "Si:ch211-225h24.2; Uncharacterized protein LOC564539", "gene_name": "si:ch211-225h24.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC564539", "refseq_ac": [ { "id": "NP_001373431", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373431", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-225h24.2; fb75c07; wu:fb75c07", "gene_names_refseq": "fb75c07; si:ch211-225h24.2; wu:fb75c07", "protein_names_uniprotkb": "Si:ch211-225h24.2; Uncharacterized protein LOC564539", "protein_names_refseq": "uncharacterized protein LOC564539", "tax_id": 7955, "disease": "", "pathway": " (dre:564539)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12618376;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588732.4467121.1, EH560133.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505382, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Aug 24, 2020 this sequence version replaced XP_692960.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UV11", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IDJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDK5-1", "uniprot_id": [ { "id": "A0A0R4IDK5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDK5", "type": "external" } ], "mass": 49391.0, "length": 436, "protein_name": "Serine/threonine-protein kinase 40", "gene_name": "stk40", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "stk40", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase 40; 2.7.11.1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:564859)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "May be a negative regulator of NF-kappa-B and p53-mediated gene transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UV17", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDK5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDN5-1", "uniprot_id": [ { "id": "A0A0R4IDN5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDN5", "type": "external" } ], "mass": 47215.0, "length": 418, "protein_name": "Sorting nexin 8b; Sorting nexin-8 isoform X1", "gene_name": "snx8b", "organism": "Zebrafish", "refseq_name": "sorting nexin-8 isoform X1", "refseq_ac": [ { "id": "XP_009304805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304805", "type": "external" } ], "gene_names_uniprotkb": "snx8b", "gene_names_refseq": "snx8b", "protein_names_uniprotkb": "Sorting nexin 8b; Sorting nexin-8 isoform X1", "protein_names_refseq": "sorting nexin-8 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:799225)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AY83", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031901 early endosome membrane;GO:0016020 membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034498 early endosome to Golgi transport;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDN5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDP3-1", "uniprot_id": [ { "id": "ZH15A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDP3", "type": "external" } ], "mass": 37352.0, "length": 328, "protein_name": "Palmitoyltransferase ZDHHC15A", "gene_name": "zdhhc15a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "zdhhc15a", "gene_names_refseq": "", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC15A; 2.3.1.-; 2.3.1.225; Acyltransferase ZDHHC15A; Zinc finger DHHC domain-containing protein 15A", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (By similarity). Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). May thereby regulate target proteins association and localization to membranes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0019705 protein-cysteine S-myristoyltransferase activity;GO:0140439 protein-cysteine S-stearoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0014069 postsynaptic density", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0072657 protein localization to membrane;GO:0016188 synaptic vesicle maturation;GO:0140450 protein targeting to Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDP3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDV7-1", "uniprot_id": [ { "id": "A0A0R4IDV7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDV7", "type": "external" } ], "mass": 29717.0, "length": 265, "protein_name": "Neurexophilin", "gene_name": "nxph2b", "organism": "Zebrafish", "refseq_name": "neurexophilin-2b precursor", "refseq_ac": [ { "id": "NP_001313335", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313335", "type": "external" } ], "gene_names_uniprotkb": "nxph2b", "gene_names_refseq": "nxph2b", "protein_names_uniprotkb": "Neurexophilin", "protein_names_refseq": "neurexophilin-2b precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:797297)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH591562.1, EH589911.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476755, SAMEA4476758 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 17, 2016 this sequence version replaced XP_001337769.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May be signaling molecules that resemble neuropeptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7X2", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IDV7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDX8-1", "uniprot_id": [ { "id": "A0A0R4IDX8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDX8", "type": "external" } ], "mass": 43964.0, "length": 382, "protein_name": "Uncharacterized protein isoform X1; Zgc:174703", "gene_name": "si:dkey-122c11.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_017211186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211186", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-122c11.4; zgc:174703", "gene_names_refseq": "si:dkey-122c11.4; zgc:174703", "protein_names_uniprotkb": "Uncharacterized protein isoform X1; Zgc:174703", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100533191)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;32296464", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YYN5;E7F6G1", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IDX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDX9-1", "uniprot_id": [ { "id": "NINJ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDX9", "type": "external" } ], "mass": 16131.0, "length": 146, "protein_name": "Ninjurin-1", "gene_name": "ninj1", "organism": "Zebrafish", "refseq_name": "ninjurin-1", "refseq_ac": [ { "id": "NP_001410993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410993", "type": "external" } ], "gene_names_uniprotkb": "ninj1; si:ch1073-278o19.1", "gene_names_refseq": "ninj1; si:ch1073-278o19.1", "protein_names_uniprotkb": "Ninjurin-1; Nerve injury-induced protein 1", "protein_names_refseq": "nerve injury-induced protein 1; ninjurin-1", "tax_id": 7955, "disease": "", "pathway": " (dre:100150223)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;31091274", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1717606.1, GFIL01016067.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476750, SAMEA4476758 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000011.1. On Aug 31, 2023 this sequence version replaced XP_001919024.1., [RefSeq]; Effector of various programmed cell death, such as pyroptosis and necroptosis, which mediates plasma membrane rupture (cytolysis) (By similarity). Oligomerizes in response to death stimuli and forms ring-like structures on the plasma membrane: acts by cutting and shedding membrane disks, like a cookie cutter, leading to membrane damage and loss that cannot be repaired by the cell (By similarity). Plasma membrane rupture leads to release intracellular molecules named damage-associated molecular patterns (DAMPs) that propagate the inflammatory response (By similarity). Mechanistically, mediates plasma membrane rupture by introducing hydrophilic faces of 2 alpha helices into the hydrophobic membrane (By similarity). Induces plasma membrane rupture downstream of Gasdermin (GSDMA, GSDMB, GSDMC, GSDMD, or GSDME) or MLKL during pyroptosis or necroptosis, respectively (By similarity). Also acts as an effector of PANoptosis and ferroptosis (By similarity). Induces plasma membrane rupture in response to cell swelling caused by osmotic stress (By similarity). Acts as a regulator of Toll-like receptor 4 (TLR4) signaling triggered by lipopolysaccharide (LPS) during systemic inflammation; directly binds LPS (By similarity). Involved in leukocyte migration during inflammation by promoting transendothelial migration of macrophages via homotypic binding (By similarity). Promotes the migration of monocytes across the brain endothelium to central nervous system inflammatory lesions (By similarity). Also acts as a homophilic transmembrane adhesion molecule involved in various processes such as axonal growth, cell chemotaxis and angiogenesis (By similarity). Promotes cell adhesion by mediating homophilic interactions via its extracellular N-terminal adhesion motif (N-NAM) (By similarity). Also involved in striated muscle growth and differentiation (PubMed:31091274)., [UniProtKB, UniProtKB, PubMed, UniProtKB]; We assessed the physiological role of ninjurin1 in zebrafish during heart and skeletal muscle development...Reduced levels of ninjurin1 impaired cardiac and skeletal muscle development in zebrafish Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001530 lipopolysaccharide binding;GO:0098631 cell adhesion mediator activity;GO:0140912 membrane destabilizing activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0097060 synaptic membrane;GO:0016020 membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0007507 heart development;GO:0050729 positive regulation of inflammatory response;GO:0042246 tissue regeneration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IDX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDY5-1", "uniprot_id": [ { "id": "A0A0R4IDY5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDY5", "type": "external" } ], "mass": 27643.0, "length": 260, "protein_name": "chymotrypsin", "gene_name": "zgc:171592", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100003031 precursor", "refseq_ac": [ { "id": "NP_001104713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104713", "type": "external" } ], "gene_names_uniprotkb": "zgc:171592", "gene_names_refseq": "zgc:171592", "protein_names_uniprotkb": "chymotrypsin; 3.4.21.1", "protein_names_refseq": "uncharacterized protein LOC100003031 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100003031)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC153984.1, EH446092.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1 and EH446092.1. On or before Mar 13, 2018 this sequence version replaced XP_017206707.1, NP_001104713.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YTB3", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IDY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDY8-1", "uniprot_id": [ { "id": "A0A0R4IDY8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDY8", "type": "external" } ], "mass": 46246.0, "length": 399, "protein_name": "Butyrophilin subfamily 3 member A1-like; Si:ch73-364h19.2", "gene_name": "si:ch73-364h19.2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:ch73-364h19.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Butyrophilin subfamily 3 member A1-like; Si:ch73-364h19.2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100537438)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1REX5", "ec_number_list": [], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IDY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IDZ4-1", "uniprot_id": [ { "id": "A0A0R4IDZ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IDZ4", "type": "external" } ], "mass": 93827.0, "length": 835, "protein_name": "Olfactory receptor C family, g2; Olfactory receptor CG2 precursor", "gene_name": "olfcg2", "organism": "Zebrafish", "refseq_name": "olfactory receptor CG2", "refseq_ac": [ { "id": "NP_001103759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103759", "type": "external" } ], "gene_names_uniprotkb": "olfcg2; si:dkey-245i2.8", "gene_names_refseq": "olfcg2; si:dkey-245i2.8", "protein_names_uniprotkb": "Olfactory receptor C family, g2; Olfactory receptor CG2 precursor", "protein_names_refseq": "A04; Dr9-2; olfactory receptor CG2; pheromone receptor-like; putative pheromone receptor; sub 9_5; v2ra4", "tax_id": 7955, "disease": "", "pathway": " (dre:100004628)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Nov 16, 2007 this sequence version replaced XP_001343881.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NGA9", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IDZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IE17-1", "uniprot_id": [ { "id": "A0A0R4IE17_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IE17", "type": "external" } ], "mass": 102590.0, "length": 930, "protein_name": "LIF receptor subunit alpha a", "gene_name": "lifra", "organism": "Zebrafish", "refseq_name": "LIF receptor subunit alpha a precursor", "refseq_ac": [ { "id": "NP_001014328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014328", "type": "external" } ], "gene_names_uniprotkb": "lifra; lifr.a; zgc:112989", "gene_names_refseq": "lifr.a; lifra; zgc:112989", "protein_names_uniprotkb": "LIF receptor subunit alpha a", "protein_names_refseq": "LIF receptor subunit alpha a precursor; leukemia inhibitory factor receptor alpha a; leukemia inhibitory factor receptor.a", "tax_id": 7955, "disease": "CAKUT (Disease Ontology:DOID:0080205); primary localized cutaneous amyloidosis 1 (Disease Ontology:DOID:0080930); osteochondrodysplasia (Disease Ontology:DOID:2256)", "pathway": " (dre:541493); (R-DRE-6788467)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "17640376;23594743;23901114;25162623;25263554;27189481;30267687;33527896;35134499", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC091862.1, GDQH01000961.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR318610.8. On Aug 19, 2015 this sequence version replaced NP_001014328.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IC29;A0A8M1N4U6", "ec_number_list": [], "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019221 cytokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IE17-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IE30-1", "uniprot_id": [ { "id": "A0A0R4IE30_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IE30", "type": "external" } ], "mass": 11330.0, "length": 104, "protein_name": "Regulator of cell cycle RGCC-like; Si:dkey-27i16.2", "gene_name": "si:dkey-27i16.2", "organism": "Zebrafish", "refseq_name": "regulator of cell cycle RGCC-like", "refseq_ac": [ { "id": "NP_001373406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373406", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-27i16.2; cb124; sb:cb124", "gene_names_refseq": "cb124; sb:cb124; si:dkey-27i16.2", "protein_names_uniprotkb": "Regulator of cell cycle RGCC-like; Si:dkey-27i16.2", "protein_names_refseq": "regulator of cell cycle RGCC-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100005903)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01037405.1, GDQH01017612.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 24, 2020 this sequence version replaced XP_001344817.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1Q296", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IE30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IE38-1", "uniprot_id": [ { "id": "A0A0R4IE38_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IE38", "type": "external" } ], "mass": 10685.0, "length": 94, "protein_name": "Small ubiquitin-related modifier", "gene_name": "sumo2a", "organism": "Zebrafish", "refseq_name": "small ubiquitin like modifier 2a", "refseq_ac": [ { "id": "NP_001373345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373345", "type": "external" } ], "gene_names_uniprotkb": "sumo2a; si:ch211-108p22.3", "gene_names_refseq": "si:ch211-108p22.3; sumo2a", "protein_names_uniprotkb": "Small ubiquitin-related modifier; SUMO", "protein_names_refseq": "SMT3 suppressor of mif two 3 homolog 2a; small ubiquitin like modifier 2a", "tax_id": 7955, "disease": "", "pathway": " (dre:100334083)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395017.944115.1, SRR26395039.401284.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Aug 22, 2020 this sequence version replaced XP_002662402.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RH96", "ec_number_list": [], "go_molecular_function": "GO:0044389 ubiquitin-like protein ligase binding;GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0016925 protein sumoylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IE38-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IE49-1", "uniprot_id": [ { "id": "A0A0R4IE49_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IE49", "type": "external" } ], "mass": 25180.0, "length": 228, "protein_name": "SPRY domain-containing SOCS box protein 3; Si:dkey-23n7.10", "gene_name": "si:dkey-23n7.10", "organism": "Zebrafish", "refseq_name": "SPRY domain-containing SOCS box protein 3", "refseq_ac": [ { "id": "XP_002662894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662894", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-23n7.10", "gene_names_refseq": "si:dkey-23n7.10", "protein_names_uniprotkb": "SPRY domain-containing SOCS box protein 3; Si:dkey-23n7.10", "protein_names_refseq": "SPRY domain-containing SOCS box protein 3", "tax_id": 7955, "disease": "", "pathway": " (dre:100333689)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002662894.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RLX9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IE49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IE73-1", "uniprot_id": [ { "id": "A0A0R4IE73_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IE73", "type": "external" } ], "mass": 41546.0, "length": 374, "protein_name": "Dual specificity protein phosphatase", "gene_name": "dusp7", "organism": "Zebrafish", "refseq_name": "dual specificity protein phosphatase 7", "refseq_ac": [ { "id": "NP_956068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956068", "type": "external" } ], "gene_names_uniprotkb": "dusp7; fd19d04; wu:fd19d04; zgc:55957; zgc:77211", "gene_names_refseq": "dusp7; fd19d04; wu:fd19d04; zgc:55957; zgc:77211", "protein_names_uniprotkb": "Dual specificity protein phosphatase; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity phosphatase 6; dual specificity protein phosphatase 7", "tax_id": 7955, "disease": "", "pathway": " (dre:327246); (R-DRE-112409); (R-DRE-202670); (R-DRE-5675221)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "19445916;23594743;27189481;31787979", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC066600.1, SRR26395028.670763.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA4476743 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jan 29, 2016 this sequence version replaced NP_956068.2. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PEJ2", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IE73-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IE87-1", "uniprot_id": [ { "id": "A0A0R4IE87_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IE87", "type": "external" } ], "mass": 6674.0, "length": 63, "protein_name": "Metallothionein", "gene_name": "mtbl", "organism": "Zebrafish", "refseq_name": "metallothionein-B-like", "refseq_ac": [ { "id": "NP_001188398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188398", "type": "external" } ], "gene_names_uniprotkb": "mtbl; mt-b", "gene_names_refseq": "mt-b; mtbl", "protein_names_uniprotkb": "Metallothionein", "protein_names_refseq": "metallothionein-B-like; smtB", "tax_id": 7955, "disease": "", "pathway": " (dre:569445)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "18579444;21147257;22387671;23594743;26025641;26198291;27329524;28315003;28617195;31839624;33407100", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH488466.1, EH503413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH488466.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Metallothioneins have a high content of cysteine residues that bind various heavy metals., [UniProtKB, UniProtKB, UniProtKB]; Report expression of similar to metallothionein-B(smt-B) upon cadmium exposure and cold shock in zebrafish (Danio rerio)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NYX3", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IE87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEA1-1", "uniprot_id": [ { "id": "A0A0R4IEA1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEA1", "type": "external" } ], "mass": 8126.0, "length": 76, "protein_name": "Ovomucoid; Serine peptidase inhibitor, Kazal type 2, tandem duplicate 3", "gene_name": "spink2.3", "organism": "Zebrafish", "refseq_name": "ovomucoid", "refseq_ac": [ { "id": "XP_005157264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157264", "type": "external" } ], "gene_names_uniprotkb": "spink2.3", "gene_names_refseq": "spink2.3", "protein_names_uniprotkb": "Ovomucoid; Serine peptidase inhibitor, Kazal type 2, tandem duplicate 3", "protein_names_refseq": "ovomucoid", "tax_id": 7955, "disease": "spermatogenic failure 29 (Disease Ontology:DOID:0111930)", "pathway": " (dre:101882741)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3K0", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IEA1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEA6-1", "uniprot_id": [ { "id": "A0A0R4IEA6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEA6", "type": "external" } ], "mass": 51585.0, "length": 443, "protein_name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "gene_name": "ppp2r2bb", "organism": "Zebrafish", "refseq_name": "protein phosphatase 2, regulatory subunit B, beta b", "refseq_ac": [ { "id": "NP_001025293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025293", "type": "external" } ], "gene_names_uniprotkb": "ppp2r2bb; ppp2r2b; zgc:101861", "gene_names_refseq": "ppp2r2bb; ppp2r2b; zgc:101861", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "protein_names_refseq": "protein phosphatase 2, regulatory subunit B, beta b", "tax_id": 7955, "disease": "spinocerebellar ataxia type 12 (Disease Ontology:DOID:0050962); Alzheimer's disease (Disease Ontology:DOID:10652); breast cancer (Disease Ontology:DOID:1612); systemic lupus erythematosus (Disease Ontology:DOID:9074); brain disease (Disease Ontology:DOID:936)", "pathway": " (dre:558810)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27296292;33015043", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031237.1, SRR32588718.25569338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Nov 1, 2008 this sequence version replaced NP_001025293.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N7E1", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IEA6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IED7-1", "uniprot_id": [ { "id": "A0A0R4IED7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IED7", "type": "external" } ], "mass": 49838.0, "length": 441, "protein_name": "Rab GDP dissociation inhibitor", "gene_name": "zgc:112334", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC619199", "refseq_ac": [ { "id": "NP_001307001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307001", "type": "external" } ], "gene_names_uniprotkb": "zgc:112334", "gene_names_refseq": "zgc:112334", "protein_names_uniprotkb": "Rab GDP dissociation inhibitor", "protein_names_refseq": "uncharacterized protein LOC619199", "tax_id": 7955, "disease": "", "pathway": " (dre:619199)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12477932;23594743;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.1255960.1, SRR32588729.7368899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476739 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments, RNA-seq data and orthologous data., [RefSeq]; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP., [UniProtKB, UniProtKB]; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8K7", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005093 Rab GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0015031 protein transport;GO:0007264 small GTPase-mediated signal transduction;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IED7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEE2-1", "uniprot_id": [ { "id": "A0A0R4IEE2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEE2", "type": "external" } ], "mass": 40429.0, "length": 353, "protein_name": "Trace amine-associated receptor 13c-like; Trace amine-associated receptor 19d", "gene_name": "taar19d", "organism": "Zebrafish", "refseq_name": "trace amine-associated receptor 13c-like", "refseq_ac": [ { "id": "XP_001921516", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921516", "type": "external" } ], "gene_names_uniprotkb": "taar19d", "gene_names_refseq": "taar19d", "protein_names_uniprotkb": "Trace amine-associated receptor 13c-like; Trace amine-associated receptor 19d", "protein_names_refseq": "trace amine-associated receptor 13c-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100149675); (R-DRE-375280)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_001921516.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QLE7", "ec_number_list": [], "go_molecular_function": "GO:0001594 trace-amine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IEE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEE5-1", "uniprot_id": [ { "id": "A0A0R4IEE5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEE5", "type": "external" } ], "mass": 167628.0, "length": 1481, "protein_name": "Si:ch211-261d7.6; Zinc finger protein 721", "gene_name": "si:ch211-261d7.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-261d7.6", "refseq_ac": [ { "id": "XP_017206987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206987", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-261d7.6", "gene_names_refseq": "si:ch211-261d7.6", "protein_names_uniprotkb": "Si:ch211-261d7.6; Zinc finger protein 721", "protein_names_refseq": "uncharacterized protein si:ch211-261d7.6", "tax_id": 7955, "disease": "", "pathway": " (dre:108179605)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YTM6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IEE5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEG0-1", "uniprot_id": [ { "id": "A0A0R4IEG0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEG0", "type": "external" } ], "mass": 57462.0, "length": 521, "protein_name": "Novopsin-10; Opsin 9", "gene_name": "opn9", "organism": "Zebrafish", "refseq_name": "opsin 9", "refseq_ac": [ { "id": "NP_001304680", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304680", "type": "external" } ], "gene_names_uniprotkb": "opn9; Opn5m2; si:dkey-260g12.4", "gene_names_refseq": "Opn5m2; opn9; si:dkey-260g12.4", "protein_names_uniprotkb": "Novopsin-10; Opsin 9", "protein_names_refseq": "novopsin-10; opsin 9", "tax_id": 7955, "disease": "", "pathway": " (dre:101882119)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23594743;26450929;27167972;32922310;33011634;34509581", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KT008424.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KT008424.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A2R8RHR0", "ec_number_list": [], "go_molecular_function": "GO:0008020 G protein-coupled photoreceptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007602 phototransduction;GO:0071482 cellular response to light stimulus", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IEG0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEH4-1", "uniprot_id": [ { "id": "A0A0R4IEH4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEH4", "type": "external" } ], "mass": 106731.0, "length": 967, "protein_name": "Netrin receptor UNC5", "gene_name": "unc5da", "organism": "Zebrafish", "refseq_name": "unc-5 netrin receptor Da precursor", "refseq_ac": [ { "id": "NP_001315278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315278", "type": "external" } ], "gene_names_uniprotkb": "unc5da; unc5d", "gene_names_refseq": "unc5da; unc5d", "protein_names_uniprotkb": "Netrin receptor UNC5", "protein_names_refseq": "unc-5 homolog Da; unc-5 homolog D; unc-5 netrin receptor Da precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:566274)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;23806443;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01042735.1, SRR32588730.10812539.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_001315278.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and RNA-seq and orthologous data., [RefSeq]; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4P1", "ec_number_list": [], "go_molecular_function": "GO:0005042 netrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IEH4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEH8-1", "uniprot_id": [ { "id": "A0A0R4IEH8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEH8", "type": "external" } ], "mass": 63659.0, "length": 549, "protein_name": "E3 ubiquitin-protein ligase TRIM39; Zgc:173581", "gene_name": "zgc:173581", "organism": "Zebrafish", "refseq_name": "zgc:173581", "refseq_ac": [ { "id": "NP_001410659", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410659", "type": "external" } ], "gene_names_uniprotkb": "zgc:173581", "gene_names_refseq": "zgc:173581", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM39; Zgc:173581", "protein_names_refseq": "zgc:173581", "tax_id": 7955, "disease": "", "pathway": " (dre:100137104); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588716.12982189.1, SRR32588728.33541701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476744, SAMEA4476798 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Sep 19, 2024 this sequence version replaced XP_017207880.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YUP7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IEH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEK2-1", "uniprot_id": [ { "id": "A0A0R4IEK2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEK2", "type": "external" } ], "mass": 42007.0, "length": 373, "protein_name": "G protein-coupled receptor 132b; Probable G-protein coupled receptor 132b", "gene_name": "gpr132b", "organism": "Zebrafish", "refseq_name": "probable G-protein coupled receptor 132b", "refseq_ac": [ { "id": "NP_001020718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020718", "type": "external" } ], "gene_names_uniprotkb": "gpr132b; si:ch211-20b12.2; zgc:136260", "gene_names_refseq": "gpr132b; si:ch211-20b12.2; zgc:136260", "protein_names_uniprotkb": "G protein-coupled receptor 132b; Probable G-protein coupled receptor 132b", "protein_names_refseq": "G protein-coupled receptor -like; probable G-protein coupled receptor 132b", "tax_id": 7955, "disease": "autoimmune disease (Disease Ontology:DOID:417)", "pathway": " (dre:566903); (R-DRE-373076); (R-DRE-416476)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "23594743;26614909;27424497;30139917;33785593;36122226", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC116473.1, GDQH01021230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Nov 26, 2014 this sequence version replaced NP_001020718.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; GPR132 responds to a select panel of oxygenated polyunsaturated fatty acids to enhance both embryonic and adult hematopoiesis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N701", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0010447 response to acidic pH;GO:0010972 negative regulation of G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IEK2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "uniprot_id": [ { "id": "A0A0R4IEQ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEQ0", "type": "external" } ], "mass": 47017.0, "length": 400, "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "organism": "Zebrafish", "refseq_name": "guanine nucleotide-binding protein subunit alpha-11a", "refseq_ac": [ { "id": "NP_001038501", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038501", "type": "external" } ], "gene_names_uniprotkb": "gna11a; gna11; si:dkey-42p8.2", "gene_names_refseq": "gna11a; gna11; si:dkey-42p8.2", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit alpha", "protein_names_refseq": "G11-2; Galpha 11b; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide-binding protein subunit alpha-11a", "tax_id": 7955, "disease": "familial hypocalciuric hypercalcemia 2 (Disease Ontology:DOID:0060701); autosomal dominant hypocalcemia 2 (Disease Ontology:DOID:0090108)", "pathway": " (dre:563953)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "15520368;19164534;20333216;21242316;21452212;23594743;25184495;28252024;34816109;35255436;35816398", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On Sep 1, 2006 this sequence version replaced XP_692405.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1YX09", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IEQ0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEQ1-1", "uniprot_id": [ { "id": "A0A0R4IEQ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEQ1", "type": "external" } ], "mass": 28153.0, "length": 245, "protein_name": "Si:dkey-30e9.6; Uncharacterized protein LOC564083 isoform 1", "gene_name": "si:dkey-30e9.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC564083 isoform 1", "refseq_ac": [ { "id": "NP_001373152", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373152", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-30e9.6", "gene_names_refseq": "si:dkey-30e9.6", "protein_names_uniprotkb": "Si:dkey-30e9.6; Uncharacterized protein LOC564083 isoform 1", "protein_names_refseq": "uncharacterized protein LOC564083 isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:564083)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01034451.1, EH440509.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 15, 2020 this sequence version replaced XP_706281.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFM3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IEQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEQ2-1", "uniprot_id": [ { "id": "A0A0R4IEQ2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEQ2", "type": "external" } ], "mass": 41358.0, "length": 385, "protein_name": "Solute carrier family 30 member 10; Zinc transporter 10", "gene_name": "slc30a10", "organism": "Zebrafish", "refseq_name": "calcium/manganese antiporter SLC30A10", "refseq_ac": [ { "id": "NP_001121706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121706", "type": "external" } ], "gene_names_uniprotkb": "slc30a10; ZnT10", "gene_names_refseq": "ZnT10; slc30a10", "protein_names_uniprotkb": "Solute carrier family 30 member 10; Zinc transporter 10", "protein_names_refseq": "calcium/manganese antiporter SLC30A10; solute carrier family 30 (zinc transporter), member 10", "tax_id": 7955, "disease": "hypermanganesemia with dystonia 1 (Disease Ontology:DOID:0080536)", "pathway": " (dre:555724); (R-DRE-425410)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "11698295;16689696;23594743;27411634;28692648;35429189;36044573", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.54654022.1, SRR32588728.28588260.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Apr 20, 2018 this sequence version replaced XP_009305899.1, NP_001121706.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Xpressing either wild-type or mutant forms of SLC30A10 was sufficient to inhibit the effect of ATP2C1 in response to Mn challenge in both zebrafish embryos and HeLa cells. These findings suggest that either activating ATP2C1 or restoring the Mn-induced trafficking of ATP2C1 can reduce Mn accumulation, providing a possible target for treating HMDPC. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AZG9", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0010312 detoxification of zinc ion;GO:0071577 zinc ion transmembrane transport;GO:0006882 intracellular zinc ion homeostasis;GO:0006828 manganese ion transport;GO:0055071 manganese ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IEQ2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IES2-1", "uniprot_id": [ { "id": "A0A0R4IES2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IES2", "type": "external" } ], "mass": 8413.0, "length": 78, "protein_name": "Si:dkey-203a12.5; Uncharacterized protein LOC100537943 precursor", "gene_name": "spink2.8", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100537943 precursor", "refseq_ac": [ { "id": "NP_001373478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373478", "type": "external" } ], "gene_names_uniprotkb": "spink2.8; si:dkey-203a12.5", "gene_names_refseq": "si:dkey-203a12.5; spink2.8", "protein_names_uniprotkb": "Si:dkey-203a12.5; Uncharacterized protein LOC100537943 precursor", "protein_names_refseq": "uncharacterized protein LOC100537943 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100537943)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH479302.1, BM181484.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_003199923.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RSZ7", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IES2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IES7-1", "uniprot_id": [ { "id": "BLTP1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IES7", "type": "external" } ], "mass": 545451.0, "length": 4923, "protein_name": "Bridge-like lipid transfer protein family member 1", "gene_name": "bltp1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "bltp1; si:ch211-233a24.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Bridge-like lipid transfer protein family member 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23594743;29290337", "class_list": "", "function": "Bridge-like lipid transfer protein that functions as molecular bridges between endoplasmic reticulum and the membranes targeted for lipid delivery (By similarity). Forms a tunnel with multiple beta-grooves that allows the transport of phospholipids (By similarity). Plays a role in endosomal trafficking and endosome recycling (By similarity). Also involved in the actin cytoskeleton and cilia structural dynamics (By similarity). Acts as a regulator of phagocytosis (By similarity). Required for the formation of endoplasmic reticulum-plasma membrane junctions which are critical for lipid exchange (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1904121 phosphatidylethanolamine transfer activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane;GO:0098793 presynapse;GO:0140268 endoplasmic reticulum-plasma membrane contact site", "go_biological_process": "GO:0006909 phagocytosis;GO:0016197 endosomal transport;GO:0032456 endocytic recycling;GO:0120009 intermembrane lipid transfer;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IES7-1", "record_type": "protein", "filter_code": "0000000.0000100.000100.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEU4-1", "uniprot_id": [ { "id": "A0A0R4IEU4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEU4", "type": "external" } ], "mass": 111375.0, "length": 979, "protein_name": "ELKS/RAB6-interacting/CAST family member 1a; ELKS/Rab6-interacting/CAST family member 1 isoform X1", "gene_name": "erc1a", "organism": "Zebrafish", "refseq_name": "ELKS/Rab6-interacting/CAST family member 1a isoform X1", "refseq_ac": [ { "id": "XP_009296278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296278", "type": "external" } ], "gene_names_uniprotkb": "erc1a; LOC548606; zgc:198416", "gene_names_refseq": "erc1a; zgc:198416", "protein_names_uniprotkb": "ELKS/RAB6-interacting/CAST family member 1a; ELKS/Rab6-interacting/CAST family member 1 isoform X1", "protein_names_refseq": "ELKS/Rab6-interacting/CAST family member 1a isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:548606)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3APQ9", "ec_number_list": [], "go_molecular_function": "GO:0098882 structural constituent of presynaptic active zone", "go_cellular_component": "GO:0098831 presynaptic active zone cytoplasmic component;GO:0005856 cytoskeleton;GO:0030424 axon;GO:0098793 presynapse", "go_biological_process": "GO:0048790 maintenance of presynaptic active zone structure", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IEU4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEV6-1", "uniprot_id": [ { "id": "A0A0R4IEV6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEV6", "type": "external" } ], "mass": 12027.0, "length": 107, "protein_name": "Si:ch211-202f5.3", "gene_name": "si:ch211-202f5.3", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "si:ch211-202f5.3", "gene_names_refseq": "", "protein_names_uniprotkb": "Si:ch211-202f5.3", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:795321)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QEW8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IEV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IEW8-1", "uniprot_id": [ { "id": "ELAV4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IEW8", "type": "external" } ], "mass": 45258.0, "length": 411, "protein_name": "ELAV-like protein 4", "gene_name": "elavl4", "organism": "Zebrafish", "refseq_name": "ELAV-like protein 4 isoform 1", "refseq_ac": [ { "id": "NP_001231529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231529", "type": "external" } ], "gene_names_uniprotkb": "elavl4; elrd; hud; wu:fc24h01", "gene_names_refseq": "elavl4; elrd; hud; wu:fc24h01", "protein_names_uniprotkb": "ELAV-like protein 4; Protein elrD", "protein_names_refseq": "ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV-like protein 4 isoform 1; ELAV-like protein 4; elav-related D; embryonic lethal, abnormal vision-related D; protein elrD", "tax_id": 7955, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446); hypothyroidism (Disease Ontology:DOID:1459); status epilepticus (Disease Ontology:DOID:1824); learning disability (Disease Ontology:DOID:8927)", "pathway": " (dre:30737)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;29061699;7753842", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01009546.1, SRR32588727.2737415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On or before Aug 1, 2025 this sequence version replaced XP_073765205.1, NP_001231529.1. Sequence Note:. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs (By similarity). Plays a role in the regulation of mRNA stability, alternative splicing and translation (By similarity). Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Mainly plays a role in neuron-specific RNA processing (By similarity). Required for the maturation of motor neuron axonal branches and dendrites (PubMed:29061699)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q6NZU5;Q90409", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030424 axon;GO:0030425 dendrite;GO:0030426 growth cone;GO:0043204 perikaryon", "go_biological_process": "GO:0006397 mRNA processing;GO:0007409 axonogenesis;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IEW8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IF19-1", "uniprot_id": [ { "id": "A0A0R4IF19_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IF19", "type": "external" } ], "mass": 8513.0, "length": 76, "protein_name": "Serine peptidase inhibitor, Kazal type 2, tandem duplicate 5", "gene_name": "spink2.5", "organism": "Zebrafish", "refseq_name": "serine peptidase inhibitor, Kazal type 2, tandem duplicate 5 precursor", "refseq_ac": [ { "id": "NP_001373551", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373551", "type": "external" } ], "gene_names_uniprotkb": "spink2.5; si:dkey-203a12.8", "gene_names_refseq": "si:dkey-203a12.8; spink2.5", "protein_names_uniprotkb": "Serine peptidase inhibitor, Kazal type 2, tandem duplicate 5", "protein_names_refseq": "serine peptidase inhibitor, Kazal type 2, tandem duplicate 5 precursor", "tax_id": 7955, "disease": "spermatogenic failure 29 (Disease Ontology:DOID:0111930)", "pathway": " (dre:100538065)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH440396.1, EH476902.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708829, SAMEA708835 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 29, 2020 this sequence version replaced XP_003199926.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RJ21", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IF19-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IF32-1", "uniprot_id": [ { "id": "A0A0R4IF32_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IF32", "type": "external" } ], "mass": 62198.0, "length": 553, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "si:dkey-192d15.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC557558", "refseq_ac": [ { "id": "NP_001314756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314756", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-192d15.2", "gene_names_refseq": "si:dkey-192d15.1; si:dkey-192d15.2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "uncharacterized protein LOC557558", "tax_id": 7955, "disease": "", "pathway": " (dre:141375244); (R-DRE-381426); (R-DRE-8957275)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX005456.6. On May 26, 2016 this sequence version replaced XP_009301118.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8C4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "3.1.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.98", "type": "external" }, { "id": "3.4.21.112", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.112", "type": "external" }, { "id": "3.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.51", "type": "external" }, { "id": "3.4.21.69", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.69", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IF32-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IF61-1", "uniprot_id": [ { "id": "A0A0R4IF61_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IF61", "type": "external" } ], "mass": 65232.0, "length": 598, "protein_name": "Amino acid transporter", "gene_name": "slc1a8a", "organism": "Zebrafish", "refseq_name": "excitatory amino acid transporter 5 isoform X1", "refseq_ac": [ { "id": "XP_699303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699303", "type": "external" } ], "gene_names_uniprotkb": "slc1a8a", "gene_names_refseq": "slc1a8a", "protein_names_uniprotkb": "Amino acid transporter", "protein_names_refseq": "excitatory amino acid transporter 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_699303.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UW35", "ec_number_list": [], "go_molecular_function": "GO:0015175 neutral L-amino acid transmembrane transporter activity;GO:0015501 glutamate:sodium symporter activity;GO:0005313 L-glutamate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0015813 L-glutamate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IF61-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IF65-1", "uniprot_id": [ { "id": "A0A0R4IF65_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IF65", "type": "external" } ], "mass": 100048.0, "length": 889, "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "organism": "Zebrafish", "refseq_name": "DNA replication licensing factor MCM2", "refseq_ac": [ { "id": "NP_775364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775364", "type": "external" } ], "gene_names_uniprotkb": "mcm2; cb737; chunp6905", "gene_names_refseq": "cb737; chunp6905; mcm2", "protein_names_uniprotkb": "DNA replication licensing factor MCM2; 3.6.4.12; DNA replication licensing factor mcm2", "protein_names_refseq": "DNA replication licensing factor MCM2; MCM2 minichromosome maintenance deficient 2, mitotin", "tax_id": 7955, "disease": "autosomal dominant nonsyndromic deafness 70 (Disease Ontology:DOID:0110592); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (dre:192338); (R-DRE-68867); (R-DRE-68949); (R-DRE-68962); (R-DRE-69052)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "15716491;16373575;16714409;18974873;23213226;23594743;32331249;32367800;33763998;34162866;36644807", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01006067.1, BC066422.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1 and EH588242.1. On Jun 25, 2015 this sequence version replaced NP_775364.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; The foxn1-mcm2 axis plays a central role in the genetic regulatory network controlling thymus development in zebrafish, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PE13", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000228 nuclear chromosome;GO:0042555 MCM complex", "go_biological_process": "GO:0060041 retina development in camera-type eye;GO:0048538 thymus development;GO:1902017 regulation of cilium assembly;GO:1902975 mitotic DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IF65-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IF73-1", "uniprot_id": [ { "id": "A0A0R4IF73_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IF73", "type": "external" } ], "mass": 15127.0, "length": 142, "protein_name": "Protein C19orf12 homolog; Si:ch211-260e23.7", "gene_name": "si:ch211-260e23.7", "organism": "Zebrafish", "refseq_name": "protein C19orf12 homolog", "refseq_ac": [ { "id": "XP_001343826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001343826", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-260e23.7", "gene_names_refseq": "si:ch211-260e23.7", "protein_names_uniprotkb": "Protein C19orf12 homolog; Si:ch211-260e23.7", "protein_names_refseq": "protein C19orf12 homolog", "tax_id": 7955, "disease": "neurodegeneration with brain iron accumulation 4 (Disease Ontology:DOID:0110738); hereditary spastic paraplegia 43 (Disease Ontology:DOID:0110795)", "pathway": " (dre:100004554)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QHZ3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IF73-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IF99-1", "uniprot_id": [ { "id": "ZD16B_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IF99", "type": "external" } ], "mass": 44693.0, "length": 382, "protein_name": "Palmitoyltransferase ZDHHC16B", "gene_name": "zdhhc16b", "organism": "Zebrafish", "refseq_name": "palmitoyltransferase ZDHHC16B", "refseq_ac": [ { "id": "NP_001314728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314728", "type": "external" } ], "gene_names_uniprotkb": "zdhhc16b", "gene_names_refseq": "DHHC-16B; zdhhc16b; zgc:63934", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC16B; 2.3.1.225; DHHC-16B; Zinc finger DHHC domain-containing protein 16B", "protein_names_refseq": "palmitoyltransferase ZDHHC16B; probable palmitoyltransferase ZDHHC16; zinc finger DHHC domain-containing protein 16B; zinc finger DHHC-type containing 16b; zinc finger DHHC-type palmitoyltransferase 16b; zinc finger, DHHC domain containing 16b", "tax_id": 7955, "disease": "", "pathway": " (dre:393316)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395039.120516.1, SRR26395012.866180.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On May 26, 2016 this sequence version replaced XP_005156038.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Palmitoyl acyltransferase that mediates palmitoylation of proteins and is required during embryonic heart development. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IX74;F1R4N0;R4GEX6", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007507 heart development;GO:0006974 DNA damage response;GO:0021899 fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IF99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFD2-1", "uniprot_id": [ { "id": "A0A0R4IFD2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFD2", "type": "external" } ], "mass": 8086.0, "length": 75, "protein_name": "Serine peptidase inhibitor, Kazal type 2, tandem duplicate 2", "gene_name": "spink2.2", "organism": "Zebrafish", "refseq_name": "serine peptidase inhibitor, Kazal type 2, tandem duplicate 2 precursor", "refseq_ac": [ { "id": "NP_001373436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373436", "type": "external" } ], "gene_names_uniprotkb": "spink2.2; si:dkey-77g12.1", "gene_names_refseq": "si:dkey-77g12.1; spink2.2", "protein_names_uniprotkb": "Serine peptidase inhibitor, Kazal type 2, tandem duplicate 2", "protein_names_refseq": "serine peptidase inhibitor, Kazal type 2, tandem duplicate 2 precursor", "tax_id": 7955, "disease": "spermatogenic failure 29 (Disease Ontology:DOID:0111930)", "pathway": " (dre:100537783)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH533265.1, EH520185.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476744, SAMEA4476750 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 27, 2020 this sequence version replaced XP_003199919.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RMG7", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IFD2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFD5-1", "uniprot_id": [ { "id": "A0A0R4IFD5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFD5", "type": "external" } ], "mass": 127598.0, "length": 1144, "protein_name": "Ras-associating and dilute domain-containing protein-like; Si:ch73-281f12.4", "gene_name": "radil2a", "organism": "Zebrafish", "refseq_name": "Ras-associating and dilute domain-containing protein-like", "refseq_ac": [ { "id": "NP_001272317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272317", "type": "external" } ], "gene_names_uniprotkb": "radil2a; radil-b; si:ch73-281f12.4; zmp:0000000679", "gene_names_refseq": "radil-b; radil2a; si:ch73-281f12.4; zmp:0000000679", "protein_names_uniprotkb": "Ras-associating and dilute domain-containing protein-like; Si:ch73-281f12.4", "protein_names_refseq": "Ras-associated forkhead-associated dilute domain protein; Ras-associating and dilute domain-containing protein-like", "tax_id": 7955, "disease": "", "pathway": " (dre:102216267)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;34383884", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: JF519851.1, GDQH01020808.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced NP_001272317.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P667", "ec_number_list": [], "go_molecular_function": "GO:0051020 GTPase binding", "go_cellular_component": "GO:0005911 cell-cell junction", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0035024 negative regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IFD5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFG3-1", "uniprot_id": [ { "id": "A0A0R4IFG3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFG3", "type": "external" } ], "mass": 127151.0, "length": 1145, "protein_name": "Transcription termination factor 2", "gene_name": "ttf2", "organism": "Zebrafish", "refseq_name": "transcription termination factor 2", "refseq_ac": [ { "id": "XP_005168676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168676", "type": "external" } ], "gene_names_uniprotkb": "ttf2", "gene_names_refseq": "ttf2", "protein_names_uniprotkb": "Transcription termination factor 2; RNA polymerase II termination factor; Transcription release factor 2", "protein_names_refseq": "transcription termination factor 2", "tax_id": 7955, "disease": "", "pathway": " (dre:555382)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BFW3", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0006353 DNA-templated transcription termination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IFG3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFG5-1", "uniprot_id": [ { "id": "CFA53_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFG5", "type": "external" } ], "mass": 63183.0, "length": 519, "protein_name": "Cilia- and flagella-associated protein 53", "gene_name": "cfap53", "organism": "Zebrafish", "refseq_name": "cilia- and flagella-associated protein 53", "refseq_ac": [ { "id": "NP_001038595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038595", "type": "external" } ], "gene_names_uniprotkb": "cfap53; ccdc11", "gene_names_refseq": "ccdc11; cfap53; si:ch211-257i19.2; zgc:153145", "protein_names_uniprotkb": "Cilia- and flagella-associated protein 53; Coiled-coil domain-containing protein 11", "protein_names_refseq": "cilia- and flagella-associated protein 53; coiled-coil domain containing 11; coiled-coil domain-containing protein 11", "tax_id": 7955, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); visceral heterotaxy 6 (Disease Ontology:DOID:0051020)", "pathway": " (dre:567344)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;25504577;26531781;26538025", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124260.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124260.1. On Jun 3, 2007 this sequence version replaced NP_001038595.1., [RefSeq]; Cfap53 is a conserved regulator of organ laterality in both humans and zebrafish., [RefSeq, PubMed]; Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity). Regulates motility patterns of both 9+0 and 9+2 motile cilia through differential localization and recruitment of axonemal dynein components (By similarity). Required for cilium motility within the spinal canal and Kuppfer's vesicle and is involved in the establishment of left-right symmetry during embryogenesis (PubMed:25504577, PubMed:26531781, PubMed:26538025)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed, UniProtKB]; Through functional evaluation of the zebrafish homolog of the gene, study identify a critical role for the CCDC11 protein in regulating the motility of cilia within the left-right asymmetry organizer during embryogenesis., [RefSeq, PubMed]; To determine the role of CCDC11 during vertebrate development, we generated mutant alleles in zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q08CF5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005930 axoneme;GO:0005879 axonemal microtubule;GO:0097546 ciliary base", "go_biological_process": "GO:0060271 cilium assembly;GO:0007368 determination of left/right symmetry;GO:0003341 cilium movement;GO:0035082 axoneme assembly;GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IFG5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFI0-1", "uniprot_id": [ { "id": "A0A0R4IFI0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFI0", "type": "external" } ], "mass": 152557.0, "length": 1363, "protein_name": "Regulatory-associated protein of mTOR", "gene_name": "rptor", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rptor", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein", "protein_names_refseq": "", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742)", "pathway": " (dre:560455); (R-DRE-1632852); (R-DRE-165159); (R-DRE-166208); (R-DRE-3371571); (R-DRE-380972); (R-DRE-5628897); (R-DRE-8943724); (R-DRE-9639288)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3N3", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005764 lysosome;GO:0031931 TORC1 complex", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0030307 positive regulation of cell growth;GO:0006914 autophagy;GO:0009267 cellular response to starvation;GO:0038202 TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IFI0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFJ1-1", "uniprot_id": [ { "id": "A0A0R4IFJ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFJ1", "type": "external" } ], "mass": 59580.0, "length": 522, "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "dnajc7", "organism": "Zebrafish", "refseq_name": "dnaJ homolog subfamily C member 7 isoform 2", "refseq_ac": [ { "id": "NP_001428577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428577", "type": "external" } ], "gene_names_uniprotkb": "dnajc7; fj58b08; wu:fj58b08; zgc:85806", "gene_names_refseq": "dnajc7; fj58b08; wu:fj58b08; zgc:85806", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 7", "protein_names_refseq": "dnaJ homolog subfamily C member 7 isoform 2", "tax_id": 7955, "disease": "", "pathway": " (dre:406579)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15979371;21468032;23594743;24106212;26469318;27189481;28252024;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395064.1679060.1, SRR32588735.3444226.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced XP_009297610.1., [RefSeq]; Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B873", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0R4IFJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFJ3-1", "uniprot_id": [ { "id": "A0A0R4IFJ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFJ3", "type": "external" } ], "mass": 56927.0, "length": 523, "protein_name": "Large neutral amino acids transporter small subunit 1; Solute carrier family 7 member 5", "gene_name": "slc7a5", "organism": "Zebrafish", "refseq_name": "large neutral amino acids transporter small subunit 1", "refseq_ac": [ { "id": "NP_001121830", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121830", "type": "external" } ], "gene_names_uniprotkb": "slc7a5; LAT1", "gene_names_refseq": "LAT1; slc7a5", "protein_names_uniprotkb": "Large neutral amino acids transporter small subunit 1; Solute carrier family 7 member 5", "protein_names_refseq": "large neutral amino acids transporter small subunit 1; solute carrier family 7 (amino acid transporter light chain, L system), member 5", "tax_id": 7955, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); large cell neuroendocrine carcinoma (Disease Ontology:DOID:0050872); autism spectrum disorder (Disease Ontology:DOID:0060041); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); stomach cancer (Disease Ontology:DOID:10534); esophageal carcinoma (Disease Ontology:DOID:1107); esophagitis (Disease Ontology:DOID:11963); rectum adenocarcinoma (Disease Ontology:DOID:1996); colon cancer (Disease Ontology:DOID:219); glioblastoma (Disease Ontology:DOID:3068); malignant astrocytoma (Disease Ontology:DOID:3069); extrahepatic bile duct adenocarcinoma (Disease Ontology:DOID:3495); gastric adenocarcinoma (Disease Ontology:DOID:3717); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); bile duct adenocarcinoma (Disease Ontology:DOID:4896); bile duct carcinoma (Disease Ontology:DOID:4897); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); malignant pleural mesothelioma (Disease Ontology:DOID:7474); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dre:797250); (R-DRE-210991); (R-DRE-352230); (R-DRE-71240)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "23594743;25051050;25872869;26469318;27189481;28694436;30995231;31513589;32831172;33330465;33745965", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01032991.1, GFIL01025102.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000025.1. On Jul 31, 2008 this sequence version replaced XP_001919407.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 26, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NHX4", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0015175 neutral L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0015804 neutral amino acid transport;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IFJ3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFJ4-1", "uniprot_id": [ { "id": "A0A0R4IFJ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFJ4", "type": "external" } ], "mass": 129868.0, "length": 1181, "protein_name": "Pyruvate carboxylase", "gene_name": "pcxa", "organism": "Zebrafish", "refseq_name": "pyruvate carboxylase a", "refseq_ac": [ { "id": "NP_001315285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315285", "type": "external" } ], "gene_names_uniprotkb": "pcxa; PYCa; pcl; zgc:123047", "gene_names_refseq": "", "protein_names_uniprotkb": "Pyruvate carboxylase; 6.4.1.1", "protein_names_refseq": "", "tax_id": 7955, "disease": "pyruvate decarboxylase deficiency (Disease Ontology:DOID:3649); pyruvate carboxylase deficiency disease (Disease Ontology:DOID:3651)", "pathway": " (dre:553283); (R-DRE-196780); (R-DRE-70263); (R-DRE-70268)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "19500364;23594743;24611545;25754827;27189481;32849832", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01029598.1, GDQH01000183.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_001315285.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments, and RNA-seq and orthologous data., [RefSeq]; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second., [UniProtKB, UniProtKB]; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3R3", "ec_number_list": [ { "id": "6.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.1", "type": "external" }, { "id": "6.4.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.4", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004736 pyruvate carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0046959 habituation;GO:0006629 lipid metabolic process;GO:0006094 gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IFJ4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFJ7-1", "uniprot_id": [ { "id": "A0A0R4IFJ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFJ7", "type": "external" } ], "mass": 46804.0, "length": 417, "protein_name": "Creatine kinase S-type, mitochondrial", "gene_name": "ckmt2a", "organism": "Zebrafish", "refseq_name": "creatine kinase, mitochondrial 2a (sarcomeric) isoform 2", "refseq_ac": [ { "id": "NP_001295538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295538", "type": "external" } ], "gene_names_uniprotkb": "ckmt2a; fi14g08; wu:fi14g08; zgc:56085", "gene_names_refseq": "ckmt2a; fi14g08; wu:fi14g08; zgc:56085", "protein_names_uniprotkb": "Creatine kinase S-type, mitochondrial; 2.7.3.2; Sarcomeric mitochondrial creatine kinase", "protein_names_refseq": "creatine kinase, mitochondrial 2a (sarcomeric) isoform 2", "tax_id": 7955, "disease": "", "pathway": " (dre:327506); (R-DRE-71288)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "19482995;23594743;26046835;26469318;27189481;28138518;29762122;31195116;33105605;33857482", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.41835775.1, SRR32588729.29474114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH439325.1, EH115450.1, EH461171.1, JBMGRA010000010.1 and EH612110.1. Transcript Variant: This variant (2) uses an alternate internal exon compared to variant 1. The encoded isoform is the same length but differs in amino acid sequence compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P728", "ec_number_list": [ { "id": "2.7.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.3.2", "type": "external" } ], "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0R4IFJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFM9-1", "uniprot_id": [ { "id": "A0A0R4IFM9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFM9", "type": "external" } ], "mass": 57209.0, "length": 512, "protein_name": "Si:ch211-207i20.2; Uncharacterized protein LOC568537", "gene_name": "si:ch211-207i20.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC568537", "refseq_ac": [ { "id": "NP_001314833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314833", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-207i20.2", "gene_names_refseq": "si:ch211-207i20.2", "protein_names_uniprotkb": "Si:ch211-207i20.2; Uncharacterized protein LOC568537", "protein_names_refseq": "uncharacterized protein LOC568537", "tax_id": 7955, "disease": "", "pathway": " (dre:568537)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01024536.1, SRR26395028.1557442.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505387, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1, EH556516.1 and EH588984.1. On May 28, 2016 this sequence version replaced XP_003199628.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9J1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0045596 negative regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IFM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFS8-1", "uniprot_id": [ { "id": "A0A0R4IFS8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFS8", "type": "external" } ], "mass": 34722.0, "length": 308, "protein_name": "Si:dkey-182g1.10", "gene_name": "si:dkey-182g1.10", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-182g1.10", "refseq_ac": [ { "id": "XP_005161714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161714", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-182g1.10", "gene_names_refseq": "si:dkey-182g1.10", "protein_names_uniprotkb": "Si:dkey-182g1.10", "protein_names_refseq": "uncharacterized protein si:dkey-182g1.10", "tax_id": 7955, "disease": "", "pathway": " (dre:101886233)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B8I4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IFS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFY3-1", "uniprot_id": [ { "id": "A0A0R4IFY3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFY3", "type": "external" } ], "mass": 39743.0, "length": 345, "protein_name": "5-hydroxytryptamine (serotonin) receptor 5A, Genome duplicate A", "gene_name": "htr5aa", "organism": "Zebrafish", "refseq_name": "5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a", "refseq_ac": [ { "id": "NP_001119882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119882", "type": "external" } ], "gene_names_uniprotkb": "htr5aa; htr5a; si:dkey-265a7.5", "gene_names_refseq": "htr5aa; htr5a; si:dkey-265a7.5", "protein_names_uniprotkb": "5-hydroxytryptamine (serotonin) receptor 5A, Genome duplicate A", "protein_names_refseq": "5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a", "tax_id": 7955, "disease": "intracranial hypertension (Disease Ontology:DOID:9428)", "pathway": " (dre:100038775); (R-DRE-390666); (R-DRE-418594)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "23594743;26565906;26822114;27424782;27703173;28837927;32209227;32892009;33171223", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.15483633.1, SRR32588729.6873066.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476767, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On or before May 28, 2009 this sequence version replaced NP_001083024.1, NP_001119882.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NJ85", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0004938 alpha2-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IFY3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFY6-1", "uniprot_id": [ { "id": "A0A0R4IFY6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFY6", "type": "external" } ], "mass": 36943.0, "length": 321, "protein_name": "Si:dkey-57k17.1; Uncharacterized protein LOC100150830", "gene_name": "si:dkey-57k17.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100150830", "refseq_ac": [ { "id": "NP_001314815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314815", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-57k17.1", "gene_names_refseq": "si:dkey-57k17.1", "protein_names_uniprotkb": "Si:dkey-57k17.1; Uncharacterized protein LOC100150830", "protein_names_refseq": "uncharacterized protein LOC100150830", "tax_id": 7955, "disease": "", "pathway": " (dre:100150830); (R-DRE-9843940)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12477932;21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155761.1, SRR32588732.12593740.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On May 27, 2016 this sequence version replaced XP_005157313.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P968", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IFY6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IFY9-1", "uniprot_id": [ { "id": "A0A0R4IFY9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IFY9", "type": "external" } ], "mass": 41638.0, "length": 377, "protein_name": "Sterile alpha motif domain-containing 1a", "gene_name": "samd1a", "organism": "Zebrafish", "refseq_name": "sterile alpha motif domain containing 1a", "refseq_ac": [ { "id": "NP_001303918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303918", "type": "external" } ], "gene_names_uniprotkb": "samd1a; zgc:153652", "gene_names_refseq": "samd1a; zgc:153652", "protein_names_uniprotkb": "Sterile alpha motif domain-containing 1a", "protein_names_refseq": "sterile alpha motif domain containing 1a", "tax_id": 7955, "disease": "", "pathway": " (dre:768149)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;34315984", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01034409.1, GDQH01023895.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced NP_001303918.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2M5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IFY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IG09-1", "uniprot_id": [ { "id": "A0A0R4IG09_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IG09", "type": "external" } ], "mass": 28005.0, "length": 262, "protein_name": "Eukaryotic translation initiation factor 4H", "gene_name": "eif4h", "organism": "Zebrafish", "refseq_name": "eukaryotic translation initiation factor 4H isoform 1", "refseq_ac": [ { "id": "NP_001184257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184257", "type": "external" } ], "gene_names_uniprotkb": "eif4h; wbscr1; zgc:77282", "gene_names_refseq": "eif4h; wbscr1; zgc:77282", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4H", "protein_names_refseq": "Williams-Beuren syndrome chromosome region 1; eukaryotic translation initiation factor 4H isoform 1", "tax_id": 7955, "disease": "Williams-Beuren syndrome (Disease Ontology:DOID:1928)", "pathway": " (dre:402996); (R-DRE-156827); (R-DRE-72649); (R-DRE-72662); (R-DRE-72702)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "11517306;21468032;23594743;26469318;28252024;31017557;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC065640.1, SRR26395062.610911.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, FP141411.1, EH552521.1 and EH515860.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUW6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity;GO:0043024 ribosomal small subunit binding;GO:0034057 RNA strand-exchange activity;GO:0033592 RNA strand annealing activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0097010 eukaryotic translation initiation factor 4F complex assembly;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IG09-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IG59-1", "uniprot_id": [ { "id": "A0A0R4IG59_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IG59", "type": "external" } ], "mass": 26546.0, "length": 232, "protein_name": "BCL2-interacting protein 1b; Vesicle transport protein SEC20", "gene_name": "bnip1b", "organism": "Zebrafish", "refseq_name": "vesicle transport protein SEC20", "refseq_ac": [ { "id": "XP_001333725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333725", "type": "external" } ], "gene_names_uniprotkb": "bnip1b", "gene_names_refseq": "bnip1b", "protein_names_uniprotkb": "BCL2-interacting protein 1b; Vesicle transport protein SEC20", "protein_names_refseq": "vesicle transport protein SEC20", "tax_id": 7955, "disease": "Down syndrome (Disease Ontology:DOID:14250)", "pathway": " (dre:795732); (R-DRE-6811434)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_001333725.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PRW9", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0031201 SNARE complex", "go_biological_process": "GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IG59-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGE6-1", "uniprot_id": [ { "id": "A0A0R4IGE6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGE6", "type": "external" } ], "mass": 41768.0, "length": 367, "protein_name": "Endophilin-A2", "gene_name": "sh3gl1b", "organism": "Zebrafish", "refseq_name": "SH3-domain GRB2-like 1b isoform X1", "refseq_ac": [ { "id": "XP_021333879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333879", "type": "external" } ], "gene_names_uniprotkb": "sh3gl1b; cb831; sh3gl1", "gene_names_refseq": "cb831; sh3gl1b; sh3gl1", "protein_names_uniprotkb": "Endophilin-A2; Endophilin-2", "protein_names_refseq": "SH3-domain GRB2-like 1b isoform X1", "tax_id": 7955, "disease": "high grade glioma (Disease Ontology:DOID:3070); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (dre:378838)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "18413315;23539215;23594743;27189481;28252024;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Implicated in endocytosis. May recruit other proteins to membranes with high curvature., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q9K3", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0002102 podosome;GO:0031901 early endosome membrane;GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0098793 presynapse", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IGE6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGE7-1", "uniprot_id": [ { "id": "A0A0R4IGE7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGE7", "type": "external" } ], "mass": 50377.0, "length": 460, "protein_name": "Ectodysplasin A receptor; Tumor necrosis factor receptor superfamily member EDAR precursor", "gene_name": "edar", "organism": "Zebrafish", "refseq_name": "tumor necrosis factor receptor superfamily member EDAR precursor", "refseq_ac": [ { "id": "NP_001108536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108536", "type": "external" } ], "gene_names_uniprotkb": "edar; fls", "gene_names_refseq": "edar; fls", "protein_names_uniprotkb": "Ectodysplasin A receptor; Tumor necrosis factor receptor superfamily member EDAR precursor", "protein_names_refseq": "ectodysplasin receptor; finless; tumor necrosis factor receptor superfamily member EDAR precursor", "tax_id": 7955, "disease": "ectodermal dysplasia 10A (Disease Ontology:DOID:0111663); ectodermal dysplasia 10B (Disease Ontology:DOID:0111665); hypohidrotic ectodermal dysplasia (Disease Ontology:DOID:14793)", "pathway": " (dre:796370); (R-DRE-5669034)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "18833299;23594743;24173565;24821783;26134525;27504894;28835471;30014845;32398375;32647268;32703943", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588714.35892423.1, SRR32588728.21990920.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898404, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Jun 18, 2025 this sequence version replaced NP_001108536.2., [RefSeq]; Eda and edar are not required for early development but are specific for the development of adult skeletal and dental structures. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UYT0", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0046330 positive regulation of JNK cascade;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0007631 feeding behavior;GO:0060348 bone development;GO:0033333 fin development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IGE7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGF8-1", "uniprot_id": [ { "id": "A0A0R4IGF8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGF8", "type": "external" } ], "mass": 13059.0, "length": 122, "protein_name": "Lymphocyte antigen 6 family member pge", "gene_name": "ly6pge", "organism": "Zebrafish", "refseq_name": "lymphocyte antigen 6 family member pge precursor", "refseq_ac": [ { "id": "NP_001314767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314767", "type": "external" } ], "gene_names_uniprotkb": "ly6pge; si:ch73-28h20.1", "gene_names_refseq": "ly6pge; si:ch73-28h20.1", "protein_names_uniprotkb": "Lymphocyte antigen 6 family member pge", "protein_names_refseq": "lymphocyte antigen 6 family member pge precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:569792)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22415300;23594743;29196253", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH476061.1, CN513300.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1, EH450257.1 and EH476061.1. On May 26, 2016 this sequence version replaced XP_698291.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9E6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IGF8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGG5-1", "uniprot_id": [ { "id": "A0A0R4IGG5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGG5", "type": "external" } ], "mass": 44345.0, "length": 398, "protein_name": "exo-alpha-sialidase", "gene_name": "neu3.5", "organism": "Zebrafish", "refseq_name": "sialidase 3 (membrane sialidase), tandem duplicate 5 isoform X1", "refseq_ac": [ { "id": "XP_005161185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161185", "type": "external" } ], "gene_names_uniprotkb": "neu3.5; si:dkey-11j5.6", "gene_names_refseq": "neu3.5; si:dkey-11j5.6", "protein_names_uniprotkb": "exo-alpha-sialidase; 3.2.1.18", "protein_names_refseq": "sialidase 3 (membrane sialidase), tandem duplicate 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100000684)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "17708749;23032629;23594743;26469318;27189481;28252024;30405127;32686823;32980954", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B816", "ec_number_list": [], "go_molecular_function": "GO:0004308 exo-alpha-sialidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005764 lysosome", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0009313 oligosaccharide catabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IGG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGK4-1", "uniprot_id": [ { "id": "A0A0R4IGK4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGK4", "type": "external" } ], "mass": 34051.0, "length": 305, "protein_name": "Stomatin", "gene_name": "stom", "organism": "Zebrafish", "refseq_name": "stomatin isoform X1", "refseq_ac": [ { "id": "XP_017208322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208322", "type": "external" } ], "gene_names_uniprotkb": "stom; band7.2; band72; epb72; zgc:110814", "gene_names_refseq": "band7.2; band72; epb72; stom; zgc:110814", "protein_names_uniprotkb": "Stomatin", "protein_names_refseq": "stomatin isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:81534); (R-DRE-2672351); (R-DRE-6798695); (R-DRE-8980692); (R-DRE-9013026); (R-DRE-9013106); (R-DRE-9013148); (R-DRE-9013406); (R-DRE-9013407)", "pathway_count": 9, "publication_count": 8, "publication_id_list": "10207156;16109975;16466575;23594743;27189481;28252024;35226401;9537416", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z3Q4", "ec_number_list": [], "go_molecular_function": "GO:0008200 ion channel inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IGK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGK8-1", "uniprot_id": [ { "id": "A0A0R4IGK8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGK8", "type": "external" } ], "mass": 76021.0, "length": 685, "protein_name": "protein-glutamine gamma-glutamyltransferase", "gene_name": "tgm5l", "organism": "Zebrafish", "refseq_name": "transglutaminase 5, like", "refseq_ac": [ { "id": "NP_001313420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313420", "type": "external" } ], "gene_names_uniprotkb": "tgm5l; si:ch1073-277p6.1", "gene_names_refseq": "si:ch1073-277p6.1; tgm5l", "protein_names_uniprotkb": "protein-glutamine gamma-glutamyltransferase; 2.3.2.13", "protein_names_refseq": "TG-84; transglutaminase 5, like", "tax_id": 7955, "disease": "", "pathway": " (dre:565984)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21809079;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155563.1, GFIL01040757.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On May 19, 2016 this sequence version replaced XP_009300366.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P812", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003810 protein-glutamine gamma-glutamyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0007399 nervous system development;GO:0043065 positive regulation of apoptotic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IGK8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGL5-1", "uniprot_id": [ { "id": "A0A0R4IGL5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGL5", "type": "external" } ], "mass": 82017.0, "length": 732, "protein_name": "Protein zyg-11 homolog isoform X1; Si:ch1073-82l19.1", "gene_name": "zyg11l", "organism": "Zebrafish", "refseq_name": "protein zyg-11 homolog isoform X1", "refseq_ac": [ { "id": "XP_695816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695816", "type": "external" } ], "gene_names_uniprotkb": "zyg11l; si:ch1073-82l19.1", "gene_names_refseq": "zyg11l", "protein_names_uniprotkb": "Protein zyg-11 homolog isoform X1; Si:ch1073-82l19.1", "protein_names_refseq": "protein zyg-11 homolog isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:567429)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_695816.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TEE8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031462 Cul2-RING ubiquitin ligase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IGL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGL9-1", "uniprot_id": [ { "id": "A0A0R4IGL9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGL9", "type": "external" } ], "mass": 66458.0, "length": 597, "protein_name": "PWWP domain-containing 2B; PWWP domain-containing protein 2B", "gene_name": "pwwp2b", "organism": "Zebrafish", "refseq_name": "PWWP domain-containing protein 2B", "refseq_ac": [ { "id": "XP_001920864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920864", "type": "external" } ], "gene_names_uniprotkb": "pwwp2b", "gene_names_refseq": "pwwp2b", "protein_names_uniprotkb": "PWWP domain-containing 2B; PWWP domain-containing protein 2B", "protein_names_refseq": "PWWP domain-containing protein 2B", "tax_id": 7955, "disease": "", "pathway": " (dre:561643)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_001920864.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QUX5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IGL9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGP6-1", "uniprot_id": [ { "id": "A0A0R4IGP6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGP6", "type": "external" } ], "mass": 58114.0, "length": 532, "protein_name": "Pyruvate kinase", "gene_name": "pkma", "organism": "Zebrafish", "refseq_name": "pyruvate kinase PKM isoform X3", "refseq_ac": [ { "id": "XP_009291639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291639", "type": "external" } ], "gene_names_uniprotkb": "pkma; cb1029; fj33f03; pkm2a; pkm2; wu:fj33f03", "gene_names_refseq": "cb1029; fj33f03; pkm2a; pkm2; pkma; wu:fj33f03", "protein_names_uniprotkb": "Pyruvate kinase; 2.7.1.40", "protein_names_refseq": "pyruvate kinase PKM isoform X3", "tax_id": 7955, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); hypertension (Disease Ontology:DOID:10763)", "pathway": " (dre:335817); (R-DRE-6798695); (R-DRE-70171); (R-DRE-70268); (R-DRE-9861718)", "pathway_count": 5, "publication_count": 12, "publication_id_list": "17013923;21468032;23594743;24123299;24476500;24611545;34240779;35401113;35993337;36408747;36509839;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ARR1", "ec_number_list": [ { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.4.17.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.3", "type": "external" }, { "id": "3.1.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "5.3.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.2.1", "type": "external" }, { "id": "5.3.3.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.12", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.1.6.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.14", "type": "external" }, { "id": "3.4.22.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.27", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "4.1.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.4", "type": "external" }, { "id": "3.4.21.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.46", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" }, { "id": "3.5.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.23", "type": "external" }, { "id": "3.4.22.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.1", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.24.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.35", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "3.4.22.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.52", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0030955 potassium ion binding;GO:0004743 pyruvate kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032869 cellular response to insulin stimulus;GO:0002040 sprouting angiogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0R4IGP6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGP9-1", "uniprot_id": [ { "id": "A0A0R4IGP9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGP9", "type": "external" } ], "mass": 126416.0, "length": 1131, "protein_name": "Myosin binding protein Ca isoform X1; Myosin-binding protein Ca", "gene_name": "mybpc2a", "organism": "Zebrafish", "refseq_name": "myosin binding protein Ca isoform X1", "refseq_ac": [ { "id": "XP_021327155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327155", "type": "external" } ], "gene_names_uniprotkb": "mybpc2a; zgc:136545; zgc:136820", "gene_names_refseq": "mybpc2a; zgc:136545; zgc:136820", "protein_names_uniprotkb": "Myosin binding protein Ca isoform X1; Myosin-binding protein Ca", "protein_names_refseq": "myosin binding protein Ca isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:751793); (R-DRE-390522)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "23594743;27022191;27189481;30685453;33789631;36012114;36827861", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q188", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0032982 myosin filament;GO:0031430 M band", "go_biological_process": "GO:0007155 cell adhesion;GO:0045214 sarcomere organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IGP9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGR0-1", "uniprot_id": [ { "id": "A0A0R4IGR0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGR0", "type": "external" } ], "mass": 19986.0, "length": 179, "protein_name": "Ornithine decarboxylase antizyme 2a", "gene_name": "oaz2a", "organism": "Zebrafish", "refseq_name": "ornithine decarboxylase antizyme 2a", "refseq_ac": [ { "id": "NP_001291285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291285", "type": "external" } ], "gene_names_uniprotkb": "oaz2a; si:dkey-275p19.6", "gene_names_refseq": "oaz2a; si:dkey-275p19.6", "protein_names_uniprotkb": "Ornithine decarboxylase antizyme 2a", "protein_names_refseq": "ornithine decarboxylase antizyme 2a", "tax_id": 7955, "disease": "", "pathway": " (dre:100002007); (R-DRE-350562); (R-DRE-351202)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "15520368;17049757;17332016;23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH508038.1, EH456742.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## ribosomal slippage :: inferred from conservation ##RefSeq-Attributes-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EB781174.1, EB960288.1, EB885700.1 and CD602255.1. The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. Several antizyme paralogs have been described in zebrafish. This protein shares highest similarity with antizyme 2 orthologs in other species. [provided by RefSeq, Jan 2015]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6R5", "ec_number_list": [], "go_molecular_function": "GO:0008073 ornithine decarboxylase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IGR0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGS2-1", "uniprot_id": [ { "id": "A0A0R4IGS2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGS2", "type": "external" } ], "mass": 62021.0, "length": 548, "protein_name": "Si:ch73-55i23.1; Uncharacterized protein LOC100148818; Uncharacterized protein isoform X1", "gene_name": "si:ch73-55i23.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100148818", "refseq_ac": [ { "id": "NP_001191237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191237", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-55i23.1; zmp:0000001078", "gene_names_refseq": "si:ch73-55i23.1; zmp:0000001078", "protein_names_uniprotkb": "Si:ch73-55i23.1; Uncharacterized protein LOC100148818; Uncharacterized protein isoform X1", "protein_names_refseq": "phospholipase A2, group IVC (cytosolic, calcium-independent)-like; uncharacterized protein LOC100148818", "tax_id": 7955, "disease": "", "pathway": " (dre:100148818)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588716.9434689.1, SRR32588722.24759868.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Nov 25, 2014 this sequence version replaced NP_001191237.1. Sequence Note:., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1U7", "ec_number_list": [], "go_molecular_function": "GO:0047498 calcium-dependent phospholipase A2 activity;GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046475 glycerophospholipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IGS2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGT8-1", "uniprot_id": [ { "id": "A0A0R4IGT8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGT8", "type": "external" } ], "mass": 148438.0, "length": 1355, "protein_name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3", "gene_name": "magi3a", "organism": "Zebrafish", "refseq_name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform 1", "refseq_ac": [ { "id": "NP_001352122", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352122", "type": "external" } ], "gene_names_uniprotkb": "magi3a; magi3; si:ch211-139k15.1; wu:fi36a10", "gene_names_refseq": "magi3a; magi3; si:ch211-139k15.1; wu:fi36a10", "protein_names_uniprotkb": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Membrane-associated guanylate kinase inverted 3", "protein_names_refseq": "membrane associated guanylate kinase, WW and PDZ domain containing 3; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:561689)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15520368;23594743;35649360", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025754.1, SRR26395013.471502.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001352122.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9B8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IGT8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGU0-1", "uniprot_id": [ { "id": "A0A0R4IGU0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGU0", "type": "external" } ], "mass": 33209.0, "length": 296, "protein_name": "Calponin", "gene_name": "cnn1b", "organism": "Zebrafish", "refseq_name": "calponin-1 isoform X1", "refseq_ac": [ { "id": "XP_701038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_701038", "type": "external" } ], "gene_names_uniprotkb": "cnn1b", "gene_names_refseq": "cnn1b", "protein_names_uniprotkb": "Calponin", "protein_names_refseq": "calponin-1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:572250)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_701038.4. COMPLETENESS: full length., [RefSeq]; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVF7", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0051015 actin filament binding;GO:0003779 actin binding", "go_cellular_component": "GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0007015 actin filament organization;GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IGU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGU3-1", "uniprot_id": [ { "id": "A0A0R4IGU3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGU3", "type": "external" } ], "mass": 48271.0, "length": 420, "protein_name": "Uncharacterized protein KIAA0930 homolog; Zgc:172139", "gene_name": "kiaa0930", "organism": "Zebrafish", "refseq_name": "uncharacterized protein KIAA0930 homolog", "refseq_ac": [ { "id": "NP_001314712", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314712", "type": "external" } ], "gene_names_uniprotkb": "kiaa0930; si:ch73-347c12.3; zgc:172139", "gene_names_refseq": "kiaa0930; si:ch73-347c12.3; zgc:172139", "protein_names_uniprotkb": "Uncharacterized protein KIAA0930 homolog; Zgc:172139", "protein_names_refseq": "uncharacterized protein KIAA0930 homolog", "tax_id": 7955, "disease": "", "pathway": " (dre:100003412)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01022238.1, SRR26395012.1282344.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476728, SAMEA4476731 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On May 24, 2016 this sequence version replaced XP_005168637.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3Q8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IGU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGV0-1", "uniprot_id": [ { "id": "A0A0R4IGV0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGV0", "type": "external" } ], "mass": 54811.0, "length": 518, "protein_name": "INO80 complex subunit E; Uncharacterized protein LOC107988037 precursor", "gene_name": "ino80e; si:ch73-54f23.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC107988037 precursor", "refseq_ac": [ { "id": "NP_001315052", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315052", "type": "external" } ], "gene_names_uniprotkb": "ino80e; si:ch73-54f23.2; si:ch73-54f23.2; zgc:77312", "gene_names_refseq": "si:ch73-54f23.2", "protein_names_uniprotkb": "INO80 complex subunit E; Uncharacterized protein LOC107988037 precursor", "protein_names_refseq": "uncharacterized protein LOC107988037 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:107988037); (dre:402932); (R-DRE-114608)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "18442396;22566537;23594743;27189481;28934389;32196499", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01030284.1, GFIL01018157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_001315052.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9Y8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031011 Ino80 complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IGV0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IGV4-1", "uniprot_id": [ { "id": "JAM2A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IGV4", "type": "external" } ], "mass": 34651.0, "length": 307, "protein_name": "Junctional adhesion molecule 2A", "gene_name": "jam2a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "jam2a; jamb", "gene_names_refseq": "", "protein_names_uniprotkb": "Junctional adhesion molecule 2A; JAM-B; Jam2a; Junctional adhesion molecule B", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-202733); (R-DRE-216083)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22180726;23594743", "class_list": "", "function": "Junctional adhesion protein that mediates heterotypic cell-cell interactions to regulate different cellular processes (By similarity). During myogenesis, it is involved in myocyte fusion through the binding of jam3b on neighboring myocytes (PubMed:22180726)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0009986 cell surface;GO:0098636 protein complex involved in cell adhesion;GO:0070160 tight junction", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0007159 leukocyte cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IGV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH20-1", "uniprot_id": [ { "id": "A0A0R4IH20_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH20", "type": "external" } ], "mass": 46212.0, "length": 395, "protein_name": "Cytohesin 4b", "gene_name": "cyth4b", "organism": "Zebrafish", "refseq_name": "cytohesin 4b isoform 1", "refseq_ac": [ { "id": "NP_001108375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108375", "type": "external" } ], "gene_names_uniprotkb": "cyth4b; zgc:175224", "gene_names_refseq": "cyth4b; zgc:175224", "protein_names_uniprotkb": "Cytohesin 4b", "protein_names_refseq": "cytohesin 4b isoform 1", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-6811438)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23072875;23594743;27189481;28252024;31053140;34329618", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.10732002.1, GFIL01008037.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476798, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On or before Jun 26, 2025 this sequence version replaced XP_073808532.1, NP_001108375.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFX7", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "", "go_biological_process": "GO:0032012 regulation of ARF protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IH20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH22-1", "uniprot_id": [ { "id": "A0A0R4IH22_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH22", "type": "external" } ], "mass": 139932.0, "length": 1310, "protein_name": "Nuclear protein, ataxia-telangiectasia locus; Protein NPAT", "gene_name": "npat", "organism": "Zebrafish", "refseq_name": "protein NPAT isoform X1", "refseq_ac": [ { "id": "XP_690976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690976", "type": "external" } ], "gene_names_uniprotkb": "npat", "gene_names_refseq": "npat", "protein_names_uniprotkb": "Nuclear protein, ataxia-telangiectasia locus; Protein NPAT", "protein_names_refseq": "protein NPAT isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_690976.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TB69", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IH22-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH35-1", "uniprot_id": [ { "id": "A0A0R4IH35_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH35", "type": "external" } ], "mass": 78020.0, "length": 711, "protein_name": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "gene_name": "mccc1", "organism": "Zebrafish", "refseq_name": "methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "refseq_ac": [ { "id": "NP_001038380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038380", "type": "external" } ], "gene_names_uniprotkb": "mccc1; si:dkey-37m8.6; zgc:154106", "gene_names_refseq": "mccc1; si:dkey-37m8.6; zgc:154106", "protein_names_uniprotkb": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; 6.4.1.4", "protein_names_refseq": "methylcrotonoyl-CoA carboxylase 1 (alpha); methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)", "tax_id": 7955, "disease": "3-methylcrotonyl-CoA carboxylase 1 deficiency (Disease Ontology:DOID:0080579)", "pathway": " (dre:777632); (R-DRE-196780); (R-DRE-70895)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "16530355;21839851;23594743;27189481;32344036", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC125958.1, GDQQ01003777.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On Jun 25, 2025 this sequence version replaced NP_001038380.1., [RefSeq]; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9L7", "ec_number_list": [ { "id": "6.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.1", "type": "external" }, { "id": "6.4.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.4", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004485 methylcrotonoyl-CoA carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IH35-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH70-1", "uniprot_id": [ { "id": "A0A0R4IH70_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH70", "type": "external" } ], "mass": 52326.0, "length": 483, "protein_name": "GC-rich promoter-binding protein 1-like 1; Vasculin-like protein 1", "gene_name": "gpbp1l1", "organism": "Zebrafish", "refseq_name": "vasculin-like protein 1", "refseq_ac": [ { "id": "XP_021332858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332858", "type": "external" } ], "gene_names_uniprotkb": "gpbp1l1", "gene_names_refseq": "gpbp1l1", "protein_names_uniprotkb": "GC-rich promoter-binding protein 1-like 1; Vasculin-like protein 1", "protein_names_refseq": "vasculin-like protein 1", "tax_id": 7955, "disease": "", "pathway": " (dre:799876)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q0P7", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IH70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH76-1", "uniprot_id": [ { "id": "A0A0R4IH76_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH76", "type": "external" } ], "mass": 280477.0, "length": 2450, "protein_name": "Nuclear mitotic apparatus protein 1; Wu:fb44b02", "gene_name": "numa1", "organism": "Zebrafish", "refseq_name": "nuclear mitotic apparatus protein 1", "refseq_ac": [ { "id": "NP_001316910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316910", "type": "external" } ], "gene_names_uniprotkb": "numa1; NuMA; fb44b02; wu:fb44b02", "gene_names_refseq": "NuMA; fb44b02; numa1; wu:fb44b02", "protein_names_uniprotkb": "Nuclear mitotic apparatus protein 1; Wu:fb44b02", "protein_names_refseq": "nuclear mitotic apparatus protein 1", "tax_id": 7955, "disease": "", "pathway": " (dre:572344)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21074723;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01026284.1, SRR26395062.297272.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001316910.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P5E1", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005938 cell cortex", "go_biological_process": "GO:0000132 establishment of mitotic spindle orientation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IH76-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH79-1", "uniprot_id": [ { "id": "A0A0R4IH79_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH79", "type": "external" } ], "mass": 107788.0, "length": 966, "protein_name": "Lon protease homolog, mitochondrial", "gene_name": "lonp1", "organism": "Zebrafish", "refseq_name": "lon protease homolog, mitochondrial", "refseq_ac": [ { "id": "XP_691712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691712", "type": "external" } ], "gene_names_uniprotkb": "lonp1; LONP1", "gene_names_refseq": "lonp1", "protein_names_uniprotkb": "Lon protease homolog, mitochondrial; 3.4.21.53", "protein_names_refseq": "lon protease homolog, mitochondrial", "tax_id": 7955, "disease": "CODAS syndrome (Disease Ontology:DOID:0111274)", "pathway": " (dre:563257); (R-DRE-9837999)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_691712.3. COMPLETENESS: full length., [RefSeq]; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7A0", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "1.1.98.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.98.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "5.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043565 sequence-specific DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0007005 mitochondrion organization;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0009653 anatomical structure morphogenesis;GO:0051131 chaperone-mediated protein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IH79-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IH97-1", "uniprot_id": [ { "id": "A0A0R4IH97_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IH97", "type": "external" } ], "mass": 69195.0, "length": 631, "protein_name": "Aryl hydrocarbon receptor nuclear translocator-like 2; Aryl hydrocarbon receptor nuclear translocator-like protein 2", "gene_name": "bmal2", "organism": "Zebrafish", "refseq_name": "aryl hydrocarbon receptor nuclear translocator-like protein 2", "refseq_ac": [ { "id": "NP_571653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571653", "type": "external" } ], "gene_names_uniprotkb": "bmal2; arntl2; wu:fj90c09", "gene_names_refseq": "arntl2; bmal2; wu:fj90c09", "protein_names_uniprotkb": "Aryl hydrocarbon receptor nuclear translocator-like 2; Aryl hydrocarbon receptor nuclear translocator-like protein 2", "protein_names_refseq": "aryl hydrocarbon receptor nuclear translocator-like 2; aryl hydrocarbon receptor nuclear translocator-like protein 2; bmal2a; brain and muscle ARNT-like 2", "tax_id": 7955, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); hypertension (Disease Ontology:DOID:10763); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:58099)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14653994;15657039;17785416;18602103;18850331;23594743;32168317;32186706;33508534;34769181;34925060", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC128806.1, GDQH01023007.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Jun 25, 2025 this sequence version replaced NP_571653.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PBM1", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034751 aryl hydrocarbon receptor complex;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007623 circadian rhythm;GO:0009416 response to light stimulus;GO:0048513 animal organ development;GO:0009648 photoperiodism", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IH97-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHA3-1", "uniprot_id": [ { "id": "A0A0R4IHA3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHA3", "type": "external" } ], "mass": 94980.0, "length": 857, "protein_name": "Olfactory receptor C family, j1; Olfactory receptor CJ1 precursor", "gene_name": "olfcj1", "organism": "Zebrafish", "refseq_name": "olfactory receptor CJ1 precursor", "refseq_ac": [ { "id": "NP_001103761", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103761", "type": "external" } ], "gene_names_uniprotkb": "olfcj1; si:dkey-245i2.3", "gene_names_refseq": "olfcj1; si:dkey-245i2.3", "protein_names_uniprotkb": "Olfactory receptor C family, j1; Olfactory receptor CJ1 precursor", "protein_names_refseq": "Dr7-1; K01; olfactory receptor CJ1 precursor; sub 7_1; v2rk1", "tax_id": 7955, "disease": "", "pathway": " (dre:100005028)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16226854;17014738;17156446;22038944;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.1705235.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NF74", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IHA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHC6-1", "uniprot_id": [ { "id": "A0A0R4IHC6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHC6", "type": "external" } ], "mass": 85518.0, "length": 758, "protein_name": "TLR4 interactor with leucine rich repeats", "gene_name": "tril", "organism": "Zebrafish", "refseq_name": "TLR4 interactor with leucine rich repeats", "refseq_ac": [ { "id": "XP_009292463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292463", "type": "external" } ], "gene_names_uniprotkb": "tril", "gene_names_refseq": "tril", "protein_names_uniprotkb": "TLR4 interactor with leucine rich repeats", "protein_names_refseq": "TLR4 interactor with leucine rich repeats", "tax_id": 7955, "disease": "", "pathway": " (dre:448885)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AVH3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHC6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHD8-1", "uniprot_id": [ { "id": "A0A0R4IHD8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHD8", "type": "external" } ], "mass": 27845.0, "length": 256, "protein_name": "Claudin 23b; Claudin-23", "gene_name": "cldn23.2", "organism": "Zebrafish", "refseq_name": "claudin-23", "refseq_ac": [ { "id": "XP_068080024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080024", "type": "external" } ], "gene_names_uniprotkb": "cldn23.2", "gene_names_refseq": "cldn23.2", "protein_names_uniprotkb": "Claudin 23b; Claudin-23", "protein_names_refseq": "claudin-23", "tax_id": 7955, "disease": "atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": " (dre:567620)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B1T1", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0007155 cell adhesion;GO:0070830 bicellular tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHD8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHF0-1", "uniprot_id": [ { "id": "A0A0R4IHF0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHF0", "type": "external" } ], "mass": 56216.0, "length": 491, "protein_name": "Protein kinase C and casein kinase substrate in neurons 2; Protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "gene_name": "pacsin2", "organism": "Zebrafish", "refseq_name": "protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "refseq_ac": [ { "id": "XP_005168648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168648", "type": "external" } ], "gene_names_uniprotkb": "pacsin2; zgc:77519", "gene_names_refseq": "pacsin2; zgc:77519", "protein_names_uniprotkb": "Protein kinase C and casein kinase substrate in neurons 2; Protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "protein_names_refseq": "protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:404601)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16466575;19997509;23594743;26469318;27189481;30683896;35150283;35616009", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BFX2", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0030100 regulation of endocytosis;GO:0030036 actin cytoskeleton organization;GO:0007010 cytoskeleton organization;GO:0060271 cilium assembly;GO:0097320 plasma membrane tubulation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IHF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHF7-1", "uniprot_id": [ { "id": "A0A0R4IHF7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHF7", "type": "external" } ], "mass": 35876.0, "length": 321, "protein_name": "Uncharacterized protein LOC780838; Uncharacterized protein isoform X1; Zgc:158417", "gene_name": "zgc:158417", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC780838", "refseq_ac": [ { "id": "NP_001073127", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073127", "type": "external" } ], "gene_names_uniprotkb": "zgc:158417", "gene_names_refseq": "zgc:158417", "protein_names_uniprotkb": "Uncharacterized protein LOC780838; Uncharacterized protein isoform X1; Zgc:158417", "protein_names_refseq": "uncharacterized protein LOC780838", "tax_id": 7955, "disease": "", "pathway": " (dre:780838)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC127595.1, SRR32588717.45342749.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505386, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jul 18, 2012 this sequence version replaced NP_001073127.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UYG3", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IHF7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHM6-1", "uniprot_id": [ { "id": "A0A0R4IHM6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHM6", "type": "external" } ], "mass": 8159.0, "length": 72, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "gng12b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "gng12b; si:dkey-44g17.6", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "", "tax_id": 7955, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:100331581)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QFZ7", "ec_number_list": [], "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHM6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHS7-1", "uniprot_id": [ { "id": "A0A0R4IHS7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHS7", "type": "external" } ], "mass": 105308.0, "length": 928, "protein_name": "Mitotic interactor and substrate of PLK1 isoform X1; Si:ch211-262i1.3", "gene_name": "misp", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "misp", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitotic interactor and substrate of PLK1 isoform X1; Si:ch211-262i1.3", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:567688)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PVV0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHS7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHS8-1", "uniprot_id": [ { "id": "A0A0R4IHS8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHS8", "type": "external" } ], "mass": 47974.0, "length": 412, "protein_name": "Differentially expressed in FDCP 8 homolog", "gene_name": "def8", "organism": "Zebrafish", "refseq_name": "differentially expressed in FDCP 8 homolog", "refseq_ac": [ { "id": "NP_001315135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315135", "type": "external" } ], "gene_names_uniprotkb": "def8; zgc:101815", "gene_names_refseq": "def8; zgc:101815", "protein_names_uniprotkb": "Differentially expressed in FDCP 8 homolog", "protein_names_refseq": "differentially expressed in FDCP 8 homolog", "tax_id": 7955, "disease": "", "pathway": " (dre:492523)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588721.5622848.1, SRR32588735.1754521.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Jun 9, 2016 this sequence version replaced XP_009291925.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9P0", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IHS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHT5-1", "uniprot_id": [ { "id": "A0A0R4IHT5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHT5", "type": "external" } ], "mass": 69023.0, "length": 603, "protein_name": "USP6 N-terminal-like protein", "gene_name": "si:ch211-288d18.1", "organism": "Zebrafish", "refseq_name": "USP6 N-terminal-like protein", "refseq_ac": [ { "id": "XP_686696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686696", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-288d18.1", "gene_names_refseq": "si:ch211-288d18.1", "protein_names_uniprotkb": "USP6 N-terminal-like protein", "protein_names_refseq": "USP6 N-terminal-like protein", "tax_id": 7955, "disease": "", "pathway": " (dre:558401); (R-DRE-8854214)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_686696.1. COMPLETENESS: full length., [RefSeq]; Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UVQ5", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0031410 cytoplasmic vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHT5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHV2-1", "uniprot_id": [ { "id": "A0A0R4IHV2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHV2", "type": "external" } ], "mass": 63458.0, "length": 591, "protein_name": "Nucleus accumbens-associated 1, BEN and BTB (POZ) domain-containing b; Nucleus accumbens-associated protein 1 isoform X1", "gene_name": "nacc1b", "organism": "Zebrafish", "refseq_name": "nucleus accumbens-associated protein 1 isoform X4", "refseq_ac": [ { "id": "XP_001922147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922147", "type": "external" } ], "gene_names_uniprotkb": "nacc1b", "gene_names_refseq": "nacc1b", "protein_names_uniprotkb": "Nucleus accumbens-associated 1, BEN and BTB (POZ) domain-containing b; Nucleus accumbens-associated protein 1 isoform X1", "protein_names_refseq": "nucleus accumbens-associated protein 1 isoform X4", "tax_id": 7955, "disease": "", "pathway": " (dre:572093)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001922147.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QR14", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0031981 nuclear lumen", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0042127 regulation of cell population proliferation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHV2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHX2-1", "uniprot_id": [ { "id": "A0A0R4IHX2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHX2", "type": "external" } ], "mass": 65998.0, "length": 585, "protein_name": "Kelch domain-containing 4; Kelch domain-containing protein 4", "gene_name": "klhdc4", "organism": "Zebrafish", "refseq_name": "kelch domain-containing protein 4", "refseq_ac": [ { "id": "NP_001119902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119902", "type": "external" } ], "gene_names_uniprotkb": "klhdc4; fb95f04; wu:fb95f04", "gene_names_refseq": "fb95f04; klhdc4; wu:fb95f04", "protein_names_uniprotkb": "Kelch domain-containing 4; Kelch domain-containing protein 4", "protein_names_refseq": "kelch domain-containing protein 4", "tax_id": 7955, "disease": "", "pathway": " (dre:569887)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395017.408869.1, SRR26395017.751640.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 10, 2025 this sequence version replaced NP_001119902.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NGR3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHX2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHX8-1", "uniprot_id": [ { "id": "A0A0R4IHX8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHX8", "type": "external" } ], "mass": 19634.0, "length": 171, "protein_name": "2.3.1.57; Diamine acetyltransferase 2b isoform 1; Diamine acetyltransferase 2b isoform X1; Spermidine/spermine N1-acetyltransferase family member 2b", "gene_name": "sat2b", "organism": "Zebrafish", "refseq_name": "diamine acetyltransferase 2b isoform 1", "refseq_ac": [ { "id": "NP_001002554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002554", "type": "external" } ], "gene_names_uniprotkb": "sat2b; SSAT-2; zgc:92773", "gene_names_refseq": "SSAT-2; sat2b; zgc:92773", "protein_names_uniprotkb": "2.3.1.57; Diamine acetyltransferase 2b isoform 1; Diamine acetyltransferase 2b isoform X1; Spermidine/spermine N1-acetyltransferase family member 2b", "protein_names_refseq": "diamine acetyltransferase 2b isoform 1; spermidine/spermine N1-acetyltransferase 2", "tax_id": 7955, "disease": "", "pathway": " (dre:436827)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12803540;23326562;23594743;24240475;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH524328.1, EH498050.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and EH498050.1. On or before Apr 18, 2018 this sequence version replaced XP_005165549.1, NP_001002554.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Our data revealed some correlations between the sequences and functions of the zebrafish family of Ssat1 proteins, which may provide valuable information for studies of their translational regulatory mechanism, protein stability, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BCS4", "ec_number_list": [], "go_molecular_function": "GO:0004145 diamine N-acetyltransferase activity;GO:0008080 N-acetyltransferase activity;GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups", "go_cellular_component": "", "go_biological_process": "GO:0006595 polyamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IHX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHZ3-1", "uniprot_id": [ { "id": "A0A0R4IHZ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHZ3", "type": "external" } ], "mass": 27824.0, "length": 243, "protein_name": "Sb:cb1058; Uncharacterized protein LOC394209", "gene_name": "sb:cb1058", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC394209", "refseq_ac": [ { "id": "NP_001373652", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373652", "type": "external" } ], "gene_names_uniprotkb": "sb:cb1058", "gene_names_refseq": "sb:cb1058", "protein_names_uniprotkb": "Sb:cb1058; Uncharacterized protein LOC394209", "protein_names_refseq": "uncharacterized protein LOC394209", "tax_id": 7955, "disease": "", "pathway": " (dre:394209)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EE308714.1, CK870256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Sep 2, 2020 this sequence version replaced XP_002662873.1, XP_021333476.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RKA1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHZ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IHZ4-1", "uniprot_id": [ { "id": "A0A0R4IHZ4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IHZ4", "type": "external" } ], "mass": 44973.0, "length": 400, "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7c", "organism": "Zebrafish", "refseq_name": "5-hydroxytryptamine receptor 7", "refseq_ac": [ { "id": "XP_002662019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662019", "type": "external" } ], "gene_names_uniprotkb": "htr7c", "gene_names_refseq": "htr7c", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 7; Serotonin receptor 7", "protein_names_refseq": "5-hydroxytryptamine receptor 7", "tax_id": 7955, "disease": "", "pathway": " (dre:572143)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_002662019.4. COMPLETENESS: full length., [RefSeq]; G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RQY0", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0004938 alpha2-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IHZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4II06-1", "uniprot_id": [ { "id": "A0A0R4II06_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4II06", "type": "external" } ], "mass": 286382.0, "length": 2601, "protein_name": "Si:dkey-151j17.4; Uncharacterized protein lgals4 isoform X1", "gene_name": "lgals4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein lgals4 isoform X1", "refseq_ac": [ { "id": "XP_005173755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173755", "type": "external" } ], "gene_names_uniprotkb": "lgals4", "gene_names_refseq": "lgals4", "protein_names_uniprotkb": "Si:dkey-151j17.4; Uncharacterized protein lgals4 isoform X1", "protein_names_refseq": "uncharacterized protein lgals4 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:567193)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLB8", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4II06-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4II16-1", "uniprot_id": [ { "id": "A0A0R4II16_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4II16", "type": "external" } ], "mass": 29747.0, "length": 272, "protein_name": "Proteasome inhibitor PI31 subunit", "gene_name": "psmf1", "organism": "Zebrafish", "refseq_name": "proteasome inhibitor PI31 subunit", "refseq_ac": [ { "id": "NP_001002547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002547", "type": "external" } ], "gene_names_uniprotkb": "psmf1; zgc:92785", "gene_names_refseq": "psmf1; zgc:92785", "protein_names_uniprotkb": "Proteasome inhibitor PI31 subunit", "protein_names_refseq": "proteasome (prosome, macropain) inhibitor subunit 1; proteasome inhibitor PI31 subunit", "tax_id": 7955, "disease": "", "pathway": " (dre:436820)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15520368;22805612;23594743;23748566;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031653.1, EH473760.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505377, SAMEA3505378 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1, EH484771.1 and CD604800.1. On Jul 20, 2010 this sequence version replaced NP_001002547.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N0P9", "ec_number_list": [], "go_molecular_function": "GO:0004866 endopeptidase inhibitor activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000502 proteasome complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4II16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4II19-1", "uniprot_id": [ { "id": "A0A0R4II19_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4II19", "type": "external" } ], "mass": 64130.0, "length": 545, "protein_name": "Si:ch73-376l24.3; Transcription termination factor 1 isoform X1", "gene_name": "ttf1.4", "organism": "Zebrafish", "refseq_name": "transcription termination factor 1 isoform X1", "refseq_ac": [ { "id": "XP_017211868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211868", "type": "external" } ], "gene_names_uniprotkb": "ttf1.4; LOC108179110", "gene_names_refseq": "ttf1.4", "protein_names_uniprotkb": "Si:ch73-376l24.3; Transcription termination factor 1 isoform X1", "protein_names_refseq": "transcription termination factor 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:108179110)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z0Y0", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0006363 termination of RNA polymerase I transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4II19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4II42-1", "uniprot_id": [ { "id": "A0A0R4II42_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4II42", "type": "external" } ], "mass": 16222.0, "length": 140, "protein_name": "Protein CCSMST1-like; Si:ch211-231f6.6", "gene_name": "uqcc4", "organism": "Zebrafish", "refseq_name": "ubiquinol-cytochrome c reductase complex assembly factor 4", "refseq_ac": [ { "id": "NP_001373511", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373511", "type": "external" } ], "gene_names_uniprotkb": "uqcc4; c24h16orf91; si:ch211-231f6.6", "gene_names_refseq": "c24h16orf91; si:ch211-231f6.6; uqcc4", "protein_names_uniprotkb": "Protein CCSMST1-like; Si:ch211-231f6.6", "protein_names_refseq": "ubiquinol-cytochrome c reductase complex assembly factor 4", "tax_id": 7955, "disease": "", "pathway": " (dre:101882877)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01020675.1, EH528425.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476737, SAMEA4476748 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jun 25, 2025 this sequence version replaced NP_001373511.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9U8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0034551 mitochondrial respiratory chain complex III assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4II42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4II71-1", "uniprot_id": [ { "id": "A0A0R4II71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4II71", "type": "external" } ], "mass": 62815.0, "length": 538, "protein_name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1; Si:ch73-236c18.8", "gene_name": "si:ch73-236c18.8", "organism": "Zebrafish", "refseq_name": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1", "refseq_ac": [ { "id": "XP_009294109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294109", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-236c18.8; si:ch211-233g6.2", "gene_names_refseq": "si:ch211-233g6.2", "protein_names_uniprotkb": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1; Si:ch73-236c18.8", "protein_names_refseq": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100333959)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AMQ5", "ec_number_list": [], "go_molecular_function": "GO:0008832 dGTPase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0051607 defense response to virus;GO:0006203 dGTP catabolic process;GO:0045088 regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4II71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4II90-1", "uniprot_id": [ { "id": "A0A0R4II90_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4II90", "type": "external" } ], "mass": 39363.0, "length": 350, "protein_name": "Trace amine-associated receptor 13c-like; Trace amine-associated receptor 20q", "gene_name": "taar20q", "organism": "Zebrafish", "refseq_name": "trace amine-associated receptor 13c-like", "refseq_ac": [ { "id": "XP_009303902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303902", "type": "external" } ], "gene_names_uniprotkb": "taar20q", "gene_names_refseq": "taar20q", "protein_names_uniprotkb": "Trace amine-associated receptor 13c-like; Trace amine-associated receptor 20q", "protein_names_refseq": "trace amine-associated receptor 13c-like", "tax_id": 7955, "disease": "", "pathway": " (dre:101887012); (R-DRE-375280)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_009303902.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AX43", "ec_number_list": [], "go_molecular_function": "GO:0001594 trace-amine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4II90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIB7-1", "uniprot_id": [ { "id": "A0A0R4IIB7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIB7", "type": "external" } ], "mass": 56048.0, "length": 522, "protein_name": "Succinate-semialdehyde dehydrogenase", "gene_name": "aldh5a1", "organism": "Zebrafish", "refseq_name": "succinate-semialdehyde dehydrogenase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_009290813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290813", "type": "external" } ], "gene_names_uniprotkb": "aldh5a1", "gene_names_refseq": "aldh5a1", "protein_names_uniprotkb": "Succinate-semialdehyde dehydrogenase; 1.2.1.24", "protein_names_refseq": "succinate-semialdehyde dehydrogenase, mitochondrial isoform X1", "tax_id": 7955, "disease": "succinic semialdehyde dehydrogenase deficiency (Disease Ontology:DOID:0060175); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (dre:565235); (R-DRE-916853)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "18803863;20927131;22840776;23594743;28252024;31217350;32980661;35485397;38963759", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AQW4", "ec_number_list": [ { "id": "1.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.24", "type": "external" } ], "go_molecular_function": "GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009450 gamma-aminobutyric acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IIB7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIC5-1", "uniprot_id": [ { "id": "A0A0R4IIC5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIC5", "type": "external" } ], "mass": 50341.0, "length": 447, "protein_name": "Family with sequence similarity 83 member Fb; Uncharacterized protein LOC492354", "gene_name": "fam83fb", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC492354", "refseq_ac": [ { "id": "NP_001007321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007321", "type": "external" } ], "gene_names_uniprotkb": "fam83fb; zgc:92122", "gene_names_refseq": "fam83fb; zgc:92122", "protein_names_uniprotkb": "Family with sequence similarity 83 member Fb; Uncharacterized protein LOC492354", "protein_names_refseq": "uncharacterized protein LOC492354", "tax_id": 7955, "disease": "", "pathway": " (dre:492354)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC085639.1, GDQH01000911.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1, EH506757.1 and BC085639.1. On Oct 5, 2011 this sequence version replaced NP_001007321.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N373", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IIC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIC7-1", "uniprot_id": [ { "id": "A0A0R4IIC7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIC7", "type": "external" } ], "mass": 55507.0, "length": 499, "protein_name": "IKAROS family zinc finger 2; Zinc finger protein Helios isoform X1", "gene_name": "ikzf2", "organism": "Zebrafish", "refseq_name": "zinc finger protein Helios isoform X5", "refseq_ac": [ { "id": "XP_017213106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213106", "type": "external" } ], "gene_names_uniprotkb": "ikzf2; helios; si:zfos-1425h8.1", "gene_names_refseq": "ikzf2; si:zfos-1425h8.1", "protein_names_uniprotkb": "IKAROS family zinc finger 2; Zinc finger protein Helios isoform X1", "protein_names_refseq": "zinc finger protein Helios isoform X5", "tax_id": 7955, "disease": "lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dre:100150224)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "19342657;23594743;25556858;26469318;29257949", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z2F7", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IIC7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IID4-1", "uniprot_id": [ { "id": "A0A0R4IID4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IID4", "type": "external" } ], "mass": 20878.0, "length": 183, "protein_name": "Si:dkey-34d22.2; Uncharacterized protein LOC100005807", "gene_name": "si:dkey-34d22.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100005807", "refseq_ac": [ { "id": "NP_001186990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186990", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-34d22.2", "gene_names_refseq": "si:dkey-34d22.2", "protein_names_uniprotkb": "Si:dkey-34d22.2; Uncharacterized protein LOC100005807", "protein_names_refseq": "Ras-related protein Rab-39A-like; uncharacterized protein LOC100005807", "tax_id": 7955, "disease": "", "pathway": " (dre:100005807)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC154525.1, SRR32588722.13196986.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1 and BC154525.1. On or before Nov 18, 2014 this sequence version replaced XP_009290782.1, NP_001186990.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NV81", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IID4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIH3-1", "uniprot_id": [ { "id": "A0A0R4IIH3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIH3", "type": "external" } ], "mass": 51628.0, "length": 449, "protein_name": "Glycoprotein A33 (transmembrane), paralog a", "gene_name": "gpa33a", "organism": "Zebrafish", "refseq_name": "glycoprotein A33 (transmembrane), paralog a precursor", "refseq_ac": [ { "id": "NP_001108577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108577", "type": "external" } ], "gene_names_uniprotkb": "gpa33a; sc:d0144; si:zfos-1011f11.1", "gene_names_refseq": "gpa33a; sc:d0144; si:zfos-1011f11.1", "protein_names_uniprotkb": "Glycoprotein A33 (transmembrane), paralog a", "protein_names_refseq": "glycoprotein A33 (transmembrane), paralog a precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:407680)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;33829511", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC129153.1, GDQH01010484.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1 and BC067681.1. On or before Jun 11, 2015 this sequence version replaced XP_005168347.1, NP_001108577.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NG43", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IIH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIJ3-1", "uniprot_id": [ { "id": "A0A0R4IIJ3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIJ3", "type": "external" } ], "mass": 52063.0, "length": 451, "protein_name": "Tripartite motif-containing 35-23", "gene_name": "trim35-23", "organism": "Zebrafish", "refseq_name": "tripartite motif containing 35-23", "refseq_ac": [ { "id": "NP_001038426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038426", "type": "external" } ], "gene_names_uniprotkb": "trim35-23; si:ch211-175l6.4", "gene_names_refseq": "si:ch211-175l6.4; trim35-23", "protein_names_uniprotkb": "Tripartite motif-containing 35-23", "protein_names_refseq": "nuclear factor 7, ovary-like; tripartite motif containing 35-23", "tax_id": 7955, "disease": "", "pathway": " (dre:561453)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21789205;23594743;28603526", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.31189476.1, SRR32588719.10622830.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505376, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000003.1. On Sep 1, 2006 this sequence version replaced XP_689949.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9N0", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IIJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIK0-1", "uniprot_id": [ { "id": "A0A0R4IIK0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIK0", "type": "external" } ], "mass": 54972.0, "length": 506, "protein_name": "Transmembrane protease serine 13a; Transmembrane serine protease 13a", "gene_name": "tmprss13a", "organism": "Zebrafish", "refseq_name": "transmembrane protease serine 13a", "refseq_ac": [ { "id": "NP_001152984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984", "type": "external" } ], "gene_names_uniprotkb": "tmprss13a", "gene_names_refseq": "tmprss13a", "protein_names_uniprotkb": "Transmembrane protease serine 13a; Transmembrane serine protease 13a", "protein_names_refseq": "transmembrane protease serine 13a; transmembrane protease, serine 13a", "tax_id": 7955, "disease": "", "pathway": " (dre:559754)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "21906622;22922822;23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01008250.1, GFIL01041325.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001152984.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NRD3", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IIK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIL3-1", "uniprot_id": [ { "id": "A0A0R4IIL3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIL3", "type": "external" } ], "mass": 29737.0, "length": 275, "protein_name": "Aquaporin", "gene_name": "aqp11", "organism": "Zebrafish", "refseq_name": "aquaporin-11", "refseq_ac": [ { "id": "NP_001314822", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314822", "type": "external" } ], "gene_names_uniprotkb": "aqp11", "gene_names_refseq": "aqp11", "protein_names_uniprotkb": "Aquaporin", "protein_names_refseq": "aqp11b; aquaporin-11", "tax_id": 7955, "disease": "", "pathway": " (dre:553476); (R-DRE-432047)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "20149227;21118806;23594743;27189481;27935978;30951885", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01001349.1, GDQH01004656.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9I6", "ec_number_list": [], "go_molecular_function": "GO:0015267 channel activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IIL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIN5-1", "uniprot_id": [ { "id": "A0A0R4IIN5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIN5", "type": "external" } ], "mass": 71779.0, "length": 632, "protein_name": "Complement factor H like 3 isoform X1; Complement factor H-like 3", "gene_name": "cfhl3", "organism": "Zebrafish", "refseq_name": "complement factor H like 3 isoform X3", "refseq_ac": [ { "id": "XP_068072350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072350", "type": "external" } ], "gene_names_uniprotkb": "cfhl3; si:ch211-207o17.4", "gene_names_refseq": "cfhl3; si:ch211-207o17.4", "protein_names_uniprotkb": "Complement factor H like 3 isoform X1; Complement factor H-like 3", "protein_names_refseq": "complement factor H like 3 isoform X3", "tax_id": 7955, "disease": "", "pathway": " (dre:100526816); (R-DRE-977606)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "20668901;22252228;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9P476", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IIN5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIR6-1", "uniprot_id": [ { "id": "A0A0R4IIR6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIR6", "type": "external" } ], "mass": 8445.0, "length": 77, "protein_name": "Serine peptidase inhibitor, Kazal type 2, tandem duplicate 1; Serine protease inhibitor Kazal-type 2.1 precursor", "gene_name": "spink2.1", "organism": "Zebrafish", "refseq_name": "serine protease inhibitor Kazal-type 2.1 precursor", "refseq_ac": [ { "id": "NP_001185680", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185680", "type": "external" } ], "gene_names_uniprotkb": "spink2.1; zgc:158852", "gene_names_refseq": "spink2.1; zgc:158852", "protein_names_uniprotkb": "Serine peptidase inhibitor, Kazal type 2, tandem duplicate 1; Serine protease inhibitor Kazal-type 2.1 precursor", "protein_names_refseq": "serine protease inhibitor Kazal-type 2.1 precursor; serine protease inhibitor Kazal-type 2", "tax_id": 7955, "disease": "spermatogenic failure 29 (Disease Ontology:DOID:0111930)", "pathway": " (dre:565497)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EB879999.1, EH572792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1, EH553231.1 and EH572792.1. On Nov 10, 2010 this sequence version replaced XP_002664393.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUY1", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IIR6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIR8-1", "uniprot_id": [ { "id": "A0A0R4IIR8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIR8", "type": "external" } ], "mass": 73904.0, "length": 632, "protein_name": "Exocyst complex component 3-like protein 2; Si:dkey-45k15.1", "gene_name": "si:dkey-45k15.1", "organism": "Zebrafish", "refseq_name": "exocyst complex component 3 isoform X1", "refseq_ac": [ { "id": "XP_021336390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336390", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-45k15.1", "gene_names_refseq": "si:dkey-45k15.1", "protein_names_uniprotkb": "Exocyst complex component 3-like protein 2; Si:dkey-45k15.1", "protein_names_refseq": "exocyst complex component 3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101882842)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QNL3", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding", "go_cellular_component": "GO:0000145 exocyst", "go_biological_process": "GO:0051601 exocyst localization;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IIR8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIT7-1", "uniprot_id": [ { "id": "A0A0R4IIT7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIT7", "type": "external" } ], "mass": 27205.0, "length": 234, "protein_name": "Si:ch73-138e16.2; Uncharacterized protein LOC100005958; Uncharacterized protein isoform X1", "gene_name": "znf1186", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100005958", "refseq_ac": [ { "id": "NP_001093566", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093566", "type": "external" } ], "gene_names_uniprotkb": "znf1186; si:ch73-138e16.2", "gene_names_refseq": "si:ch73-138e16.2; znf1186", "protein_names_uniprotkb": "Si:ch73-138e16.2; Uncharacterized protein LOC100005958; Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein LOC100005958; zinc finger protein 347-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100005958)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;31307377", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DN598755.1, SRR32588716.1942148.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jul 26, 2007 this sequence version replaced XP_001344852.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NE54", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IIT7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIV9-1", "uniprot_id": [ { "id": "A0A0R4IIV9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIV9", "type": "external" } ], "mass": 38248.0, "length": 343, "protein_name": "THUMP domain-containing protein 1", "gene_name": "thumpd1", "organism": "Zebrafish", "refseq_name": "THUMP domain-containing protein 1", "refseq_ac": [ { "id": "NP_991220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991220", "type": "external" } ], "gene_names_uniprotkb": "thumpd1; zgc:77221", "gene_names_refseq": "thumpd1; zgc:77221", "protein_names_uniprotkb": "THUMP domain-containing protein 1", "protein_names_refseq": "THUMP domain-containing protein 1", "tax_id": 7955, "disease": "", "pathway": " (dre:402955)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12477932;21873635;23594743;31053140", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01020502.1, DT869836.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1, EH494342.1 and EH520668.1. On Jun 16, 2015 this sequence version replaced NP_991220.1., [RefSeq]; Functions as a tRNA-binding adapter to mediate NAT10-dependent tRNA acetylation modifying cytidine to N4-acetylcytidine (ac4C)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PEU6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "", "go_biological_process": "GO:0006400 tRNA modification", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IIV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IIY6-1", "uniprot_id": [ { "id": "A0A0R4IIY6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IIY6", "type": "external" } ], "mass": 58863.0, "length": 510, "protein_name": "Si:ch73-221f6.1; Zinc finger protein 883", "gene_name": "si:ch73-221f6.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-221f6.1 isoform X1", "refseq_ac": [ { "id": "XP_009294177", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294177", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-221f6.1", "gene_names_refseq": "si:ch73-221f6.1", "protein_names_uniprotkb": "Si:ch73-221f6.1; Zinc finger protein 883", "protein_names_refseq": "uncharacterized protein si:ch73-221f6.1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:103909514)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AMR9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IIY6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJ07-1", "uniprot_id": [ { "id": "A0A0R4IJ07_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJ07", "type": "external" } ], "mass": 147177.0, "length": 1311, "protein_name": "Elongator complex protein 1", "gene_name": "elp1", "organism": "Zebrafish", "refseq_name": "elongator complex protein 1 isoform X1", "refseq_ac": [ { "id": "XP_689534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689534", "type": "external" } ], "gene_names_uniprotkb": "elp1", "gene_names_refseq": "elp1", "protein_names_uniprotkb": "Elongator complex protein 1", "protein_names_refseq": "elongator complex protein 1 isoform X1", "tax_id": 7955, "disease": "hemophagocytic lymphohistiocytosis (Disease Ontology:DOID:0050120); medulloblastoma (Disease Ontology:DOID:0050902); scoliosis (Disease Ontology:DOID:0060249); Riley-Day syndrome (Disease Ontology:DOID:11589); asthma (Disease Ontology:DOID:2841); kyphosis (Disease Ontology:DOID:4667)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_689534.4. COMPLETENESS: full length., [RefSeq]; Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TER5", "ec_number_list": [], "go_molecular_function": "GO:0000049 tRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0033588 elongator holoenzyme complex", "go_biological_process": "GO:0048484 enteric nervous system development;GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJ07-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJ50-1", "uniprot_id": [ { "id": "A0A0R4IJ50_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJ50", "type": "external" } ], "mass": 50233.0, "length": 447, "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "hdhd5", "organism": "Zebrafish", "refseq_name": "haloacid dehalogenase-like hydrolase domain-containing 5", "refseq_ac": [ { "id": "NP_001315451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315451", "type": "external" } ], "gene_names_uniprotkb": "hdhd5; cecr5; zgc:175154", "gene_names_refseq": "cecr5; hdhd5; zgc:175154", "protein_names_uniprotkb": "Haloacid dehalogenase-like hydrolase domain-containing 5", "protein_names_refseq": "cat eye syndrome chromosome region, candidate 5; haloacid dehalogenase-like hydrolase domain-containing 5", "tax_id": 7955, "disease": "", "pathway": " (dre:100137610)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007236.1, GDQQ01011690.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505378, SAMEA4476735 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 25, 2025 this sequence version replaced NP_001315451.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9A5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0046474 glycerophospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IJ50-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJ62-1", "uniprot_id": [ { "id": "A0A0R4IJ62_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJ62", "type": "external" } ], "mass": 94159.0, "length": 840, "protein_name": "Olfactory receptor C family, g1; Olfactory receptor CG1 precursor", "gene_name": "olfcg1", "organism": "Zebrafish", "refseq_name": "olfactory receptor CG1", "refseq_ac": [ { "id": "NP_001153312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153312", "type": "external" } ], "gene_names_uniprotkb": "olfcg1; si:dkey-245i2.13", "gene_names_refseq": "olfcg1; si:dkey-245i2.13", "protein_names_uniprotkb": "Olfactory receptor C family, g1; Olfactory receptor CG1 precursor", "protein_names_refseq": "7 transmembrane receptor (metabotropic glutamate family) protein; A03; Dr9-6; olfactory receptor CG1; sub 9_12; sub 9_4; sub 9_8; v2ra3", "tax_id": 7955, "disease": "", "pathway": " (dre:100147940)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16226854;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505380, SAMEA3505383 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On May 8, 2009 this sequence version replaced XP_001919205.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NRE7", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IJ62-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJ94-1", "uniprot_id": [ { "id": "A0A0R4IJ94_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJ94", "type": "external" } ], "mass": 47671.0, "length": 424, "protein_name": "FinTRIM family, member 67", "gene_name": "ftr67", "organism": "Zebrafish", "refseq_name": "finTRIM family, member 67", "refseq_ac": [ { "id": "NP_001034808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034808", "type": "external" } ], "gene_names_uniprotkb": "ftr67; wu:fb13h06; zgc:136688", "gene_names_refseq": "ftr67; wu:fb13h06; zgc:136688", "protein_names_uniprotkb": "FinTRIM family, member 67", "protein_names_refseq": "finTRIM family, member 67", "tax_id": 7955, "disease": "", "pathway": " (dre:336567); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "19196451;21789205;23594743;28461211;28476675;30550990;32334126;36801427", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC114247.1, GDQH01013375.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505379 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Jun 25, 2025 this sequence version replaced NP_001034808.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; FTR67, a member of the fish-specific finTRIM family, triggers IFN pathway and against spring viremia of carp virus., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N8D6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IJ94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJB6-1", "uniprot_id": [ { "id": "A0A0R4IJB6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJB6", "type": "external" } ], "mass": 24237.0, "length": 208, "protein_name": "Leukemia NUP98 fusion partner 1; Si:ch73-29l19.1", "gene_name": "si:ch73-29l19.1", "organism": "Zebrafish", "refseq_name": "leukemia NUP98 fusion partner 1 isoform X1", "refseq_ac": [ { "id": "XP_001923860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923860", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-29l19.1", "gene_names_refseq": "si:ch73-29l19.1", "protein_names_uniprotkb": "Leukemia NUP98 fusion partner 1; Si:ch73-29l19.1", "protein_names_refseq": "leukemia NUP98 fusion partner 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100148308)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QLU4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJB7-1", "uniprot_id": [ { "id": "A0A0R4IJB7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJB7", "type": "external" } ], "mass": 21295.0, "length": 183, "protein_name": "Regulator of G-protein signaling 21; Si:ch211-117l17.5", "gene_name": "rgs13b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rgs13b; si:ch211-117l17.5", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulator of G-protein signaling 21; Si:ch211-117l17.5", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:792554); (R-DRE-416476); (R-DRE-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PEJ4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0009968 negative regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJC7-1", "uniprot_id": [ { "id": "A0A0R4IJC7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJC7", "type": "external" } ], "mass": 79330.0, "length": 715, "protein_name": "ATP-dependent zinc metalloprotease YME1L1", "gene_name": "yme1l1b", "organism": "Zebrafish", "refseq_name": "ATP-dependent zinc metalloprotease YME1L1b", "refseq_ac": [ { "id": "NP_001317997", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001317997", "type": "external" } ], "gene_names_uniprotkb": "yme1l1b; ftsh1; yme1l1; zgc:162158", "gene_names_refseq": "ftsh1; yme1l1b; yme1l1; zgc:162158", "protein_names_uniprotkb": "ATP-dependent zinc metalloprotease YME1L1; ATP-dependent metalloprotease FtsH1; YME1-like protein 1", "protein_names_refseq": "ATP-dependent metalloprotease FtsH1; ATP-dependent zinc metalloprotease YME1L1b", "tax_id": 7955, "disease": "optic atrophy 11 (Disease Ontology:DOID:0111436)", "pathway": " (dre:557907); (R-DRE-8949664); (R-DRE-9840373)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10843804;23594743;26039894", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1717953.1, SRR26395014.1531560.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Sep 8, 2016 this sequence version replaced XP_009295158.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Characterization of the human YME1-like 1 ortholog., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P496", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0010636 positive regulation of mitochondrial fusion;GO:0007005 mitochondrion organization;GO:0034982 mitochondrial protein processing;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IJC7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJE4-1", "uniprot_id": [ { "id": "A0A0R4IJE4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJE4", "type": "external" } ], "mass": 38843.0, "length": 347, "protein_name": "Caspase-8", "gene_name": "casp20", "organism": "Zebrafish", "refseq_name": "caspase 20, apoptosis-related cysteine peptidase", "refseq_ac": [ { "id": "NP_001129724", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129724", "type": "external" } ], "gene_names_uniprotkb": "casp20; caspxa; zgc:194469", "gene_names_refseq": "casp20; caspxa; zgc:194469", "protein_names_uniprotkb": "Caspase-8; 3.4.22.61", "protein_names_refseq": "caspase 20, apoptosis-related cysteine peptidase; caspase Xa", "tax_id": 7955, "disease": "", "pathway": " (dre:100192215); (R-DRE-111465); (R-DRE-264870); (R-DRE-3371378); (R-DRE-5218900); (R-DRE-5357905); (R-DRE-5675482); (R-DRE-69416); (R-DRE-75108); (R-DRE-75153); (R-DRE-75158); (R-DRE-9758274)", "pathway_count": 12, "publication_count": 4, "publication_id_list": "16888647;23594743;27189481;29791492", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01046811.1, SRR26395062.1673317.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On or before Aug 18, 2023 this sequence version replaced NP_001077331.1, XP_009300496.1, NP_001129724.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AT65", "ec_number_list": [ { "id": "3.4.22.61", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.61", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" } ], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031265 CD95 death-inducing signaling complex", "go_biological_process": "GO:0006508 proteolysis;GO:0006915 apoptotic process;GO:0043525 positive regulation of neuron apoptotic process;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IJE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJJ1-1", "uniprot_id": [ { "id": "A0A0R4IJJ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJJ1", "type": "external" } ], "mass": 77956.0, "length": 678, "protein_name": "procollagen-proline 3-dioxygenase", "gene_name": "p3h2", "organism": "Zebrafish", "refseq_name": "prolyl 3-hydroxylase 2 isoform X1", "refseq_ac": [ { "id": "XP_003201113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201113", "type": "external" } ], "gene_names_uniprotkb": "p3h2", "gene_names_refseq": "p3h2", "protein_names_uniprotkb": "procollagen-proline 3-dioxygenase; 1.14.11.7", "protein_names_refseq": "prolyl 3-hydroxylase 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:566697); (R-DRE-1650814)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFU2", "ec_number_list": [ { "id": "1.14.11.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.7", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0031418 L-ascorbic acid binding;GO:0019797 procollagen-proline 3-dioxygenase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0032963 collagen metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJK4-1", "uniprot_id": [ { "id": "A0A0R4IJK4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJK4", "type": "external" } ], "mass": 26323.0, "length": 222, "protein_name": "RP9 pre-mRNA-splicing factor; Retinitis pigmentosa 9 protein isoform X1", "gene_name": "rp9", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rp9; im:7137386; zgc:103448", "gene_names_refseq": "", "protein_names_uniprotkb": "RP9 pre-mRNA-splicing factor; Retinitis pigmentosa 9 protein isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "retinitis pigmentosa 9 (Disease Ontology:DOID:0110387)", "pathway": " (dre:492481)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27189481;28694436", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B3M1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IJK4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJK6-1", "uniprot_id": [ { "id": "A0A0R4IJK6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJK6", "type": "external" } ], "mass": 51058.0, "length": 459, "protein_name": "Hepatocyte nuclear factor 4, gamma; Hepatocyte nuclear factor 4-gamma isoform X1", "gene_name": "hnf4g", "organism": "Zebrafish", "refseq_name": "hepatocyte nuclear factor 4-gamma isoform X1", "refseq_ac": [ { "id": "XP_021325864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325864", "type": "external" } ], "gene_names_uniprotkb": "hnf4g; hnf4gamma; zgc:153265", "gene_names_refseq": "hnf4gamma; hnf4g; zgc:153265", "protein_names_uniprotkb": "Hepatocyte nuclear factor 4, gamma; Hepatocyte nuclear factor 4-gamma isoform X1", "protein_names_refseq": "hepatocyte nuclear factor 4-gamma isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:557104); (R-DRE-383280)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "17997606;23594743;25711679;26469318;28385711;36218393", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PLU8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003707 nuclear steroid receptor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IJK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJK7-1", "uniprot_id": [ { "id": "A0A0R4IJK7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJK7", "type": "external" } ], "mass": 21141.0, "length": 191, "protein_name": "Lysozyme g", "gene_name": "lygl2", "organism": "Zebrafish", "refseq_name": "lysozyme g-like 2", "refseq_ac": [ { "id": "NP_001373416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373416", "type": "external" } ], "gene_names_uniprotkb": "lygl2", "gene_names_refseq": "lygl2", "protein_names_uniprotkb": "Lysozyme g; 3.2.1.17", "protein_names_refseq": "lysozyme g-like 2", "tax_id": 7955, "disease": "", "pathway": " (dre:100322265)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "19504456;22438865;22737090;23594743;27189481;36551460", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025598.1, EB903512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476742, SAMEA4476745 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 25, 2025 this sequence version replaced NP_001373416.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHM5", "ec_number_list": [], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0050830 defense response to Gram-positive bacterium;GO:0031640 killing of cells of another organism;GO:0009253 peptidoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4IJK7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJL2-1", "uniprot_id": [ { "id": "A0A0R4IJL2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJL2", "type": "external" } ], "mass": 49320.0, "length": 437, "protein_name": "Alpha-galactosidase", "gene_name": "naga", "organism": "Zebrafish", "refseq_name": "alpha-N-acetylgalactosaminidase precursor", "refseq_ac": [ { "id": "NP_001032465", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032465", "type": "external" } ], "gene_names_uniprotkb": "naga; zgc:123333", "gene_names_refseq": "naga; zgc:123333", "protein_names_uniprotkb": "Alpha-galactosidase; 3.2.1.-", "protein_names_refseq": "alpha-N-acetylgalactosaminidase precursor", "tax_id": 7955, "disease": "Schindler disease type 1 (Disease Ontology:DOID:0112318); Kanzaki disease (Disease Ontology:DOID:0112319); Fabry disease (Disease Ontology:DOID:14499); neuroaxonal dystrophy (Disease Ontology:DOID:2367); angiokeratoma (Disease Ontology:DOID:479)", "pathway": " (dre:560778)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23570992;23594743;26469318;27189481;31299224", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01006628.1, BC108078.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1, EH453970.1, EH434772.1 and EH479732.1. On Jul 20, 2010 this sequence version replaced NP_001032465.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N7Y2", "ec_number_list": [], "go_molecular_function": "GO:0004557 alpha-galactosidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005764 lysosome", "go_biological_process": "GO:0019377 glycolipid catabolic process;GO:0009311 oligosaccharide metabolic process;GO:0016139 glycoside catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IJL2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJL5-1", "uniprot_id": [ { "id": "A0A0R4IJL5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJL5", "type": "external" } ], "mass": 56503.0, "length": 498, "protein_name": "Lysophospholipid acyltransferase 2b; Membrane-bound O-acyltransferase domain-containing 2b", "gene_name": "mboat2b", "organism": "Zebrafish", "refseq_name": "lysophospholipid acyltransferase 2b", "refseq_ac": [ { "id": "NP_001265531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265531", "type": "external" } ], "gene_names_uniprotkb": "mboat2b; si:ch211-195d17.1; zgc:136552", "gene_names_refseq": "mboat2b; si:ch211-195d17.1; zgc:136552", "protein_names_uniprotkb": "Lysophospholipid acyltransferase 2b; Membrane-bound O-acyltransferase domain-containing 2b", "protein_names_refseq": "lysophospholipid acyltransferase 2b", "tax_id": 7955, "disease": "", "pathway": " (dre:692278); (R-DRE-1482788); (R-DRE-1482839)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "23594743;26469318;27189481;28252024;33757938", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.1332424.1, SRR26395039.1024364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jun 30, 2013 this sequence version replaced NP_001038716.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4D5", "ec_number_list": [], "go_molecular_function": "GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0036152 phosphatidylethanolamine acyl-chain remodeling;GO:0036151 phosphatidylcholine acyl-chain remodeling;GO:0030258 lipid modification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4IJL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJP4-1", "uniprot_id": [ { "id": "A0A0R4IJP4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJP4", "type": "external" } ], "mass": 93567.0, "length": 833, "protein_name": "Olfactory receptor C family, g5; Olfactory receptor CG5 precursor", "gene_name": "olfcg5", "organism": "Zebrafish", "refseq_name": "olfactory receptor CG5 precursor", "refseq_ac": [ { "id": "NP_001103413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103413", "type": "external" } ], "gene_names_uniprotkb": "olfcg5; si:dkey-245i2.5", "gene_names_refseq": "olfcg5; si:dkey-245i2.5", "protein_names_uniprotkb": "Olfactory receptor C family, g5; Olfactory receptor CG5 precursor", "protein_names_refseq": "A07; Dr9-5; olfactory receptor CG5 precursor; sub 9_6; v2ra7", "tax_id": 7955, "disease": "", "pathway": " (dre:100004890)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16226854;17014738;17156446;23594743;26108469;29792162;31263779", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.6644250.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Oct 14, 2007 this sequence version replaced XP_001344079.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NG47", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4IJP4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJP6-1", "uniprot_id": [ { "id": "A0A0R4IJP6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJP6", "type": "external" } ], "mass": 86888.0, "length": 750, "protein_name": "IQ motif and ubiquitin domain-containing; IQ motif and ubiquitin-like domain-containing protein isoform X1", "gene_name": "iqub", "organism": "Zebrafish", "refseq_name": "IQ motif and ubiquitin-like domain-containing protein isoform X1", "refseq_ac": [ { "id": "XP_002666923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002666923", "type": "external" } ], "gene_names_uniprotkb": "iqub", "gene_names_refseq": "iqub", "protein_names_uniprotkb": "IQ motif and ubiquitin domain-containing; IQ motif and ubiquitin-like domain-containing protein isoform X1", "protein_names_refseq": "IQ motif and ubiquitin-like domain-containing protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334576)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RS07", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031514 motile cilium;GO:0001669 acrosomal vesicle", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJS9-1", "uniprot_id": [ { "id": "A0A0R4IJS9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9", "type": "external" } ], "mass": 34725.0, "length": 312, "protein_name": "Forkhead box Q1a; Forkhead box protein Q1a", "gene_name": "foxq1a", "organism": "Zebrafish", "refseq_name": "forkhead box protein Q1a", "refseq_ac": [ { "id": "NP_001230273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273", "type": "external" } ], "gene_names_uniprotkb": "foxq1a; foxq1l; zgc:162905", "gene_names_refseq": "foxq1a; foxq1l; zgc:162905", "protein_names_uniprotkb": "Forkhead box Q1a; Forkhead box protein Q1a", "protein_names_refseq": "forkhead box protein Q1a", "tax_id": 7955, "disease": "", "pathway": " (dre:100537750)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "20055451;23594743;26469318;27829009;29534099;31917260;33530637;33809683;33944782;34613771;36284357", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: GDQH01022231.1, BC093302.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1, EH435319.1 and EH461319.1. On Aug 12, 2011 this sequence version replaced XP_003197856.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; This study provides the first genetic mutant analyses of zebrafish foxq1a and foxq1b. Foxq1a, but not foxq1b, was transcriptionally regulated during a bacterial response, while the expression of foxq1a was detected in sorted macrophages and upregulated in foxq1a-deficient mutants. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3Z1", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0009410 response to xenobiotic stimulus;GO:0009888 tissue development;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IJS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJU5-1", "uniprot_id": [ { "id": "A0A0R4IJU5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJU5", "type": "external" } ], "mass": 75392.0, "length": 695, "protein_name": "Synapsin-1", "gene_name": "syn2b", "organism": "Zebrafish", "refseq_name": "synapsin-2b", "refseq_ac": [ { "id": "NP_001314700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314700", "type": "external" } ], "gene_names_uniprotkb": "syn2b; zgc:123199", "gene_names_refseq": "syn2b; zgc:123199", "protein_names_uniprotkb": "Synapsin-1; Synapsin I", "protein_names_refseq": "synapsin-2b", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); epilepsy (Disease Ontology:DOID:1826); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dre:641578)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "20097902;23594743;23602570;24218366;25239370;26959078;27189481;29454044;30824836;35205114", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01040253.1, SRR32588727.637734.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 25, 2025 this sequence version replaced NP_001314700.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P900", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0097091 synaptic vesicle clustering;GO:0050808 synapse organization;GO:0007269 neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0R4IJU5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJV5-1", "uniprot_id": [ { "id": "A0A0R4IJV5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJV5", "type": "external" } ], "mass": 68512.0, "length": 608, "protein_name": "ATP-dependent RNA helicase", "gene_name": "ddx52", "organism": "Zebrafish", "refseq_name": "probable ATP-dependent RNA helicase DDX52", "refseq_ac": [ { "id": "NP_001037780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001037780", "type": "external" } ], "gene_names_uniprotkb": "ddx52", "gene_names_refseq": "ddx52", "protein_names_uniprotkb": "ATP-dependent RNA helicase; 3.6.4.13", "protein_names_refseq": "probable ATP-dependent RNA helicase DDX52", "tax_id": 7955, "disease": "", "pathway": " (dre:407696)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;27189481;34323273;34463754", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC085394.1, GDQH01019906.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1, EH493950.1, EH580775.1, CT716534.2 and CT698434.2. On Aug 22, 2015 this sequence version replaced NP_001037780.1., [RefSeq]; RNA helicase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N8X8", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0040008 regulation of growth;GO:0030490 maturation of SSU-rRNA;GO:0031101 fin regeneration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IJV5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJW4-1", "uniprot_id": [ { "id": "A0A0R4IJW4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJW4", "type": "external" } ], "mass": 80360.0, "length": 717, "protein_name": "CREB3 regulatory factor", "gene_name": "crebrf", "organism": "Zebrafish", "refseq_name": "CREB3 regulatory factor", "refseq_ac": [ { "id": "XP_005170343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170343", "type": "external" } ], "gene_names_uniprotkb": "crebrf", "gene_names_refseq": "crebrf", "protein_names_uniprotkb": "CREB3 regulatory factor", "protein_names_refseq": "CREB3 regulatory factor", "tax_id": 7955, "disease": "", "pathway": " (dre:100149876)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BHM9", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJX1-1", "uniprot_id": [ { "id": "A0A0R4IJX1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJX1", "type": "external" } ], "mass": 73424.0, "length": 653, "protein_name": "FAST kinase domain-containing protein 3, mitochondrial; FAST kinase domains 3", "gene_name": "fastkd3", "organism": "Zebrafish", "refseq_name": "FAST kinase domain-containing protein 3, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_001338251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338251", "type": "external" } ], "gene_names_uniprotkb": "fastkd3", "gene_names_refseq": "fastkd3", "protein_names_uniprotkb": "FAST kinase domain-containing protein 3, mitochondrial; FAST kinase domains 3", "protein_names_refseq": "FAST kinase domain-containing protein 3, mitochondrial isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100003734)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PS97", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0035770 ribonucleoprotein granule", "go_biological_process": "GO:0000963 mitochondrial RNA processing;GO:0044528 regulation of mitochondrial mRNA stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJX9-1", "uniprot_id": [ { "id": "A0A0R4IJX9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJX9", "type": "external" } ], "mass": 55561.0, "length": 498, "protein_name": "Peptidoglycan recognition protein 6", "gene_name": "pglyrp6", "organism": "Zebrafish", "refseq_name": "peptidoglycan recognition protein 6", "refseq_ac": [ { "id": "NP_001038687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038687", "type": "external" } ], "gene_names_uniprotkb": "pglyrp6", "gene_names_refseq": "pglyrp6", "protein_names_uniprotkb": "Peptidoglycan recognition protein 6", "protein_names_refseq": "peptidoglycan recognition protein 6; zfPGRP6", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "16930467;17296228;17892854;18495251;20045065;23594743;25536407;28592872;30612570;31336107;36042265", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC171349.1, DQ447204.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476813, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC171349.1 and JBMGRA010000003.1. On Sep 2, 2015 this sequence version replaced NP_001038687.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; We identified and cloned three zebrafish Peptidoglycan recognition proteins, PGLYRP-2, PGLYRP-5, and PGLYRP-6, and showed that they are highly expressed in eggs, developing embryos, and adult tissues that contact external environment, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NA85", "ec_number_list": [], "go_molecular_function": "GO:0008745 N-acetylmuramoyl-L-alanine amidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0006955 immune response;GO:0042742 defense response to bacterium;GO:0009253 peptidoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IJX9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJY0-1", "uniprot_id": [ { "id": "A0A0R4IJY0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJY0", "type": "external" } ], "mass": 53379.0, "length": 464, "protein_name": "Ribosome assembly protein METTL17, mitochondrial", "gene_name": "mettl17", "organism": "Zebrafish", "refseq_name": "ribosome assembly protein METTL17, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_009296945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296945", "type": "external" } ], "gene_names_uniprotkb": "mettl17", "gene_names_refseq": "mettl17", "protein_names_uniprotkb": "Ribosome assembly protein METTL17, mitochondrial; Methyltransferase-like protein 17", "protein_names_refseq": "ribosome assembly protein METTL17, mitochondrial isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:386901)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AXF5", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006412 translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJY0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IJZ0-1", "uniprot_id": [ { "id": "A0A0R4IJZ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IJZ0", "type": "external" } ], "mass": 110346.0, "length": 970, "protein_name": "protein kinase C", "gene_name": "pkn2a", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase N2-like", "refseq_ac": [ { "id": "XP_700704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700704", "type": "external" } ], "gene_names_uniprotkb": "pkn2a", "gene_names_refseq": "pkn2a", "protein_names_uniprotkb": "protein kinase C; 2.7.11.13", "protein_names_refseq": "serine/threonine-protein kinase N2-like", "tax_id": 7955, "disease": "", "pathway": " (dre:571965); (R-DRE-5625740); (R-DRE-8980692); (R-DRE-9013026); (R-DRE-9013106)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_700704.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T8C2", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "1.14.14.18", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.18", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0031267 small GTPase binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032154 cleavage furrow;GO:0030496 midbody", "go_biological_process": "GO:0007507 heart development;GO:0035556 intracellular signal transduction;GO:0048703 embryonic viscerocranium morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IJZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IK06-1", "uniprot_id": [ { "id": "A0A0R4IK06_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IK06", "type": "external" } ], "mass": 127657.0, "length": 1167, "protein_name": "Ankyrin repeat and FYVE domain-containing 1; Rabankyrin-5 isoform X1", "gene_name": "ankfy1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ankfy1; wu:fb69g03", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat and FYVE domain-containing 1; Rabankyrin-5 isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "Charlevoix-Saguenay spastic ataxia (Disease Ontology:DOID:0050946)", "pathway": " (dre:568480)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;24683187;28252024", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJB2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0010008 endosome membrane", "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi;GO:0090160 Golgi to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IK06-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IK17-1", "uniprot_id": [ { "id": "A0A0R4IK17_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IK17", "type": "external" } ], "mass": 143204.0, "length": 1270, "protein_name": "Erythroid differentiation regulatory factor 1; Erythroid differentiation-related factor 1 isoform X1", "gene_name": "edrf1", "organism": "Zebrafish", "refseq_name": "erythroid differentiation-related factor 1 isoform X1", "refseq_ac": [ { "id": "XP_021322968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322968", "type": "external" } ], "gene_names_uniprotkb": "edrf1", "gene_names_refseq": "edrf1", "protein_names_uniprotkb": "Erythroid differentiation regulatory factor 1; Erythroid differentiation-related factor 1 isoform X1", "protein_names_refseq": "erythroid differentiation-related factor 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:566404)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PCJ0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IK17-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IK46-1", "uniprot_id": [ { "id": "A0A0R4IK46_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IK46", "type": "external" } ], "mass": 39905.0, "length": 339, "protein_name": "FRA10A-associated CGG repeat 1; Protein FRA10AC1", "gene_name": "fra10ac1", "organism": "Zebrafish", "refseq_name": "protein FRA10AC1", "refseq_ac": [ { "id": "NP_001006006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006006", "type": "external" } ], "gene_names_uniprotkb": "fra10ac1; fb96h04; fb96h10; fc62g03; rare; wu:fb96h04; wu:fb96h10; wu:fc62g03; zgc:103767", "gene_names_refseq": "fb96h04; fb96h10; fc62g03; fra10ac1; rare; wu:fb96h04; wu:fb96h10; wu:fc62g03; zgc:103767", "protein_names_uniprotkb": "FRA10A-associated CGG repeat 1; Protein FRA10AC1", "protein_names_refseq": "fragile site, folic acid type, rare, candidate 1; protein FRA10AC1", "tax_id": 7955, "disease": "", "pathway": " (dre:449836)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16109975;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01020306.1, BC083487.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1, CN508266.1 and AI588153.1. On Sep 1, 2015 this sequence version replaced NP_001006006.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N2S1", "ec_number_list": [], "go_molecular_function": "GO:0016791 phosphatase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IK46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IK63-1", "uniprot_id": [ { "id": "A0A0R4IK63_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IK63", "type": "external" } ], "mass": 175444.0, "length": 1540, "protein_name": "Mitogen-activated protein kinase kinase kinase 4", "gene_name": "map3k4", "organism": "Zebrafish", "refseq_name": "mitogen-activated protein kinase kinase kinase 4 isoform X1", "refseq_ac": [ { "id": "XP_009305769", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305769", "type": "external" } ], "gene_names_uniprotkb": "map3k4", "gene_names_refseq": "map3k4", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 4; 2.7.11.25; MAPK/ERK kinase kinase 4", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:325488)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B876", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0048263 determination of dorsal identity;GO:0038066 p38MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IK63-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IK86-1", "uniprot_id": [ { "id": "A0A0R4IK86_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IK86", "type": "external" } ], "mass": 29118.0, "length": 255, "protein_name": "Inactive serine/threonine-protein kinase 19-like; Serine/threonine kinase 19", "gene_name": "whr1", "organism": "Zebrafish", "refseq_name": "inactive serine/threonine-protein kinase 19", "refseq_ac": [ { "id": "XP_003198226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198226", "type": "external" } ], "gene_names_uniprotkb": "whr1; LOC137487187; stk19", "gene_names_refseq": "LOC137487187", "protein_names_uniprotkb": "Inactive serine/threonine-protein kinase 19-like; Serine/threonine kinase 19", "protein_names_refseq": "inactive serine/threonine-protein kinase 19", "tax_id": 7955, "disease": "", "pathway": " (dre:137487187); (dre:57929)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21873635;23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RIK0", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IK86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IK87-1", "uniprot_id": [ { "id": "A0A0R4IK87_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IK87", "type": "external" } ], "mass": 13346.0, "length": 115, "protein_name": "Si:dkey-283b1.6", "gene_name": "si:dkey-283b1.6", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-283b1.6 isoform X1", "refseq_ac": [ { "id": "XP_002661232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661232", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-283b1.6", "gene_names_refseq": "si:dkey-283b1.6", "protein_names_uniprotkb": "Si:dkey-283b1.6", "protein_names_refseq": "uncharacterized protein si:dkey-283b1.6 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:322507)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RQV5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IK87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKA2-1", "uniprot_id": [ { "id": "A0A0R4IKA2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKA2", "type": "external" } ], "mass": 95545.0, "length": 854, "protein_name": "RE1-silencing transcription factor", "gene_name": "rest", "organism": "Zebrafish", "refseq_name": "RE1-silencing transcription factor", "refseq_ac": [ { "id": "NP_001340795", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001340795", "type": "external" } ], "gene_names_uniprotkb": "rest; NRSF", "gene_names_refseq": "NRSF; rest", "protein_names_uniprotkb": "RE1-silencing transcription factor", "protein_names_refseq": "RE-1 silencer of transcription; RE1-silencing transcription factor; neural-restrictive silencer factor", "tax_id": 7955, "disease": "gingival fibromatosis 5 (Disease Ontology:DOID:0080280); autosomal dominant nonsyndromic deafness 27 (Disease Ontology:DOID:0110556); alcohol use disorder (Disease Ontology:DOID:1574); nephroblastoma (Disease Ontology:DOID:2154)", "pathway": " (dre:564772)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16525062;20122919;20463883;21199918;21521740;23594743;25712696;25769695;27605615;31403159;36640352", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588720.2111704.1, SRR32588723.3218230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476811 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Commensal Bacteria Regulate Gene Expression and Differentiation in Vertebrate Olfactory Systems Through Transcription Factor REST., [RefSeq, PubMed]; Rest functions in zebrafish facial branchiomotor neurons nuclei to inhibit maturation until the neurons complete their migration., [RefSeq, PubMed]; Study provides behavioral analysis of zebrafish rest mutants and reveals specific behaviors that are modulated by Rest, suggests that Rest has functions in regulating an organism's ability to interact with its environment, [RefSeq, PubMed]; The transcriptional repressor rest modulates hedgehog signaling., [RefSeq, PubMed]; This study demostrated that maternal rest plays a long-term role in regulation of gene expression through snap25a/b and behavior during development., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QLP2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0014043 negative regulation of neuron maturation;GO:0021754 facial nucleus development;GO:0097475 motor neuron migration;GO:0007626 locomotory behavior;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IKA2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKB3-1", "uniprot_id": [ { "id": "A0A0R4IKB3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKB3", "type": "external" } ], "mass": 28997.0, "length": 254, "protein_name": "Si:ch211-25d12.7; Src-like-adapter 2", "gene_name": "sla2a", "organism": "Zebrafish", "refseq_name": "src-like-adapter 2", "refseq_ac": [ { "id": "XP_009304328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304328", "type": "external" } ], "gene_names_uniprotkb": "sla2a", "gene_names_refseq": "sla2a", "protein_names_uniprotkb": "Si:ch211-25d12.7; Src-like-adapter 2", "protein_names_refseq": "src-like-adapter 2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AXM4", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKB3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKC3-1", "uniprot_id": [ { "id": "A0A0R4IKC3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKC3", "type": "external" } ], "mass": 19052.0, "length": 163, "protein_name": "Interleukin", "gene_name": "il15l", "organism": "Zebrafish", "refseq_name": "interleukin 15, like isoform X1", "refseq_ac": [ { "id": "XP_005157574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157574", "type": "external" } ], "gene_names_uniprotkb": "il15l; IL-15_1; im:7142994; zgc:123044", "gene_names_refseq": "il15l; im:7142994; zgc:123044", "protein_names_uniprotkb": "Interleukin", "protein_names_refseq": "interleukin 15, like isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:494451)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "16055191;16919968;23434462;23594743;26391449;28111234;28300168;31822609;32784920", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3N9", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response;GO:0001819 positive regulation of cytokine production;GO:0045954 positive regulation of natural killer cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IKC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKC9-1", "uniprot_id": [ { "id": "A0A0R4IKC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKC9", "type": "external" } ], "mass": 140702.0, "length": 1268, "protein_name": "Basonuclin 2; Zinc finger protein basonuclin-2 isoform 1", "gene_name": "bnc2", "organism": "Zebrafish", "refseq_name": "zinc finger protein basonuclin-2 isoform 1", "refseq_ac": [ { "id": "NP_001314679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314679", "type": "external" } ], "gene_names_uniprotkb": "bnc2; bnp; coral; crl; fi18b05; poppy; si:dkey-114f6.1; wu:fi18b05", "gene_names_refseq": "bnc2; bnp; coral; crl; fi18b05; poppy; si:dkey-114f6.1; wu:fi18b05", "protein_names_uniprotkb": "Basonuclin 2; Zinc finger protein basonuclin-2 isoform 1", "protein_names_refseq": "basonuclin 2; zinc finger protein basonuclin-2 isoform 1", "tax_id": 7955, "disease": "urinary tract obstruction (Disease Ontology:DOID:5200)", "pathway": " (dre:559327)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "19956727;23594743;23737760;25374113;25558068;26469318;27189481;31051115;32629302", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.31419234.1, SRR32588719.14079853.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476740, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 13, 2025 this sequence version replaced NP_001314679.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Bnc2 acts non-autonomously to the melanophore lineage and is expressed by hypodermal cells adjacent to chromatophores during adult pigment pattern formation., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3N3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0048066 developmental pigmentation;GO:0039020 pronephric nephron tubule development", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4IKC9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKD0-1", "uniprot_id": [ { "id": "A0A0R4IKD0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKD0", "type": "external" } ], "mass": 31171.0, "length": 277, "protein_name": "Ras suppressor protein 1", "gene_name": "rsu1", "organism": "Zebrafish", "refseq_name": "ras suppressor protein 1 isoform X2", "refseq_ac": [ { "id": "XP_009295840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295840", "type": "external" } ], "gene_names_uniprotkb": "rsu1", "gene_names_refseq": "rsu1", "protein_names_uniprotkb": "Ras suppressor protein 1", "protein_names_refseq": "ras suppressor protein 1 isoform X2", "tax_id": 7955, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dre:553276)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AW58", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IKD0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKD9-1", "uniprot_id": [ { "id": "A0A0R4IKD9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKD9", "type": "external" } ], "mass": 28322.0, "length": 254, "protein_name": "Transmembrane protein 176l.4", "gene_name": "tmem176l.4", "organism": "Zebrafish", "refseq_name": "transmembrane protein 176l.4 isoform 1", "refseq_ac": [ { "id": "NP_001264249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264249", "type": "external" } ], "gene_names_uniprotkb": "tmem176l.4; fc44a11; wu:fc44a11", "gene_names_refseq": "fc44a11; tmem176l.4; wu:fc44a11", "protein_names_uniprotkb": "Transmembrane protein 176l.4", "protein_names_refseq": "transmembrane protein 176l.4 isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:100331729); (R-DRE-6798695)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "23594743;26469318;27189481;30765415", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH580583.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1, EH580583.1 and EH597963.1. On Mar 31, 2013 this sequence version replaced XP_003200313.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1)., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3X9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IKD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKE0-1", "uniprot_id": [ { "id": "A0A0R4IKE0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKE0", "type": "external" } ], "mass": 63837.0, "length": 553, "protein_name": "Calsequestrin", "gene_name": "casq1a", "organism": "Zebrafish", "refseq_name": "calsequestrin-1a precursor", "refseq_ac": [ { "id": "NP_001003620", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003620", "type": "external" } ], "gene_names_uniprotkb": "casq1a; bZ1G18.2; zgc:100957", "gene_names_refseq": "bZ1G18.2; casq1a; zgc:100957", "protein_names_uniprotkb": "Calsequestrin", "protein_names_refseq": "CSQ1; calsequestrin-1a precursor", "tax_id": 7955, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:445226)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "19837881;20878432;21256971;23594743;26585961;27189481;29636379;30252882;31468037;32372920;35893052", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155741.1, SRR32588714.38944799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On May 22, 2009 this sequence version replaced NP_001003620.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle., [UniProtKB, UniProtKB]; Three zebrafish Casqs: Casq1a, Casq1b and Casq2 were identified by mass spectrometry (Data are available via ProteomeXchange with identifier PXD002455). Skeletal and cardiac zebrafish calsequestrins share properties with mammalian Casq1 and Casq2., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N1H2", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0030018 Z disc;GO:0033018 sarcoplasmic reticulum lumen", "go_biological_process": "GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IKE0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKF0-1", "uniprot_id": [ { "id": "A0A0R4IKF0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKF0", "type": "external" } ], "mass": 30140.0, "length": 257, "protein_name": "Apolipoprotein A-Ib", "gene_name": "apoa1b", "organism": "Zebrafish", "refseq_name": "apolipoprotein A-Ib precursor", "refseq_ac": [ { "id": "NP_001093614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093614", "type": "external" } ], "gene_names_uniprotkb": "apoa1b; wu:fb66d03; wu:fd19c08; xx:sd49", "gene_names_refseq": "apoa1b; wu:fb66d03; wu:fd19c08; xx:sd49", "protein_names_uniprotkb": "Apolipoprotein A-Ib", "protein_names_refseq": "apolipoprotein A-Ib precursor", "tax_id": 7955, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); primary hypoalphalipoproteinemia 2 (Disease Ontology:DOID:0080958); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); sciatic neuropathy (Disease Ontology:DOID:11446); Budd-Chiari syndrome (Disease Ontology:DOID:11512); nephrotic syndrome (Disease Ontology:DOID:1184); familial hypercholesterolemia (Disease Ontology:DOID:13810); hypolipoproteinemia (Disease Ontology:DOID:1387); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); pancreatic cancer (Disease Ontology:DOID:1793); hepatitis C (Disease Ontology:DOID:1883); atherosclerosis (Disease Ontology:DOID:1936); arteriosclerosis (Disease Ontology:DOID:2349); multiple sclerosis (Disease Ontology:DOID:2377); transitional cell carcinoma (Disease Ontology:DOID:2671); coronary artery disease (Disease Ontology:DOID:3393); cholangiocarcinoma (Disease Ontology:DOID:4947); liver cirrhosis (Disease Ontology:DOID:5082); lung small cell carcinoma (Disease Ontology:DOID:5409); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); hepatoblastoma (Disease Ontology:DOID:687); end stage renal disease (Disease Ontology:DOID:783); hyperthyroidism (Disease Ontology:DOID:7998); systemic lupus erythematosus (Disease Ontology:DOID:9074); ocular hypertension (Disease Ontology:DOID:9282); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:100101640)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16631158;23594743;24608635;24611545;25030662;25633982;30840836;31515263;32994480;33513687;37094155", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CK872615.1, EH492121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB855858.1 and CK024997.1. On Nov 22, 2012 this sequence version replaced NP_001093614.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 34, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NE64", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0034364 high-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron;GO:0034362 low-density lipoprotein particle;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0033344 cholesterol efflux;GO:0055090 acylglycerol homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IKF0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKF7-1", "uniprot_id": [ { "id": "A0A0R4IKF7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKF7", "type": "external" } ], "mass": 63048.0, "length": 574, "protein_name": "Sulfite oxidase, mitochondrial", "gene_name": "suox", "organism": "Zebrafish", "refseq_name": "sulfite oxidase, mitochondrial", "refseq_ac": [ { "id": "NP_001313359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313359", "type": "external" } ], "gene_names_uniprotkb": "suox", "gene_names_refseq": "suox", "protein_names_uniprotkb": "Sulfite oxidase, mitochondrial; 1.8.3.1", "protein_names_refseq": "sulfite oxidase, mitochondrial", "tax_id": 7955, "disease": "isolated sulfite oxidase deficiency (Disease Ontology:DOID:0111270); inherited metabolic disorder (Disease Ontology:DOID:655)", "pathway": " (dre:566675); (R-DRE-1614517)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.1375804.1, SRR26395039.956750.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 26, 2025 this sequence version replaced NP_001313359.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7X9", "ec_number_list": [ { "id": "1.8.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.1", "type": "external" } ], "go_molecular_function": "GO:0030151 molybdenum ion binding;GO:0020037 heme binding;GO:0043546 molybdopterin cofactor binding;GO:0008482 sulfite oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0007399 nervous system development;GO:0006790 sulfur compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IKF7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKF9-1", "uniprot_id": [ { "id": "A0A0R4IKF9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKF9", "type": "external" } ], "mass": 93684.0, "length": 816, "protein_name": "CSC1-like protein 2 isoform X1; Transmembrane protein 63Ba", "gene_name": "tmem63ba", "organism": "Zebrafish", "refseq_name": "CSC1-like protein 2 isoform X1", "refseq_ac": [ { "id": "XP_005157122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157122", "type": "external" } ], "gene_names_uniprotkb": "tmem63ba", "gene_names_refseq": "tmem63ba", "protein_names_uniprotkb": "CSC1-like protein 2 isoform X1; Transmembrane protein 63Ba", "protein_names_refseq": "CSC1-like protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334023)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B361", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0005227 calcium-activated cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKG8-1", "uniprot_id": [ { "id": "A0A0R4IKG8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKG8", "type": "external" } ], "mass": 54505.0, "length": 488, "protein_name": "alanine transaminase", "gene_name": "si:ch211-217a12.1", "organism": "Zebrafish", "refseq_name": "alanine aminotransferase 2-like isoform X1", "refseq_ac": [ { "id": "XP_001919896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919896", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-217a12.1", "gene_names_refseq": "si:ch211-217a12.1", "protein_names_uniprotkb": "alanine transaminase; 2.6.1.2; Glutamate pyruvate transaminase 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2", "protein_names_refseq": "alanine aminotransferase 2-like isoform X1", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); obstructive jaundice (Disease Ontology:DOID:13603); acute kidney failure (Disease Ontology:DOID:3021); liver cancer (Disease Ontology:DOID:3571); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); amino acid metabolic disorder (Disease Ontology:DOID:9252); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (dre:100148522)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QQL4", "ec_number_list": [ { "id": "2.6.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.2", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042853 L-alanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKG8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKI2-1", "uniprot_id": [ { "id": "A0A0R4IKI2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKI2", "type": "external" } ], "mass": 113610.0, "length": 1049, "protein_name": "Mastermind-like protein 1 isoform X1; Mastermind-like transcriptional coactivator 1", "gene_name": "maml1", "organism": "Zebrafish", "refseq_name": "mastermind-like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_005157273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157273", "type": "external" } ], "gene_names_uniprotkb": "maml1", "gene_names_refseq": "maml1", "protein_names_uniprotkb": "Mastermind-like protein 1 isoform X1; Mastermind-like transcriptional coactivator 1", "protein_names_refseq": "mastermind-like protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:567335)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_005157273.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B411", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0007221 positive regulation of transcription of Notch receptor target", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKI2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKJ1-1", "uniprot_id": [ { "id": "CAPAM_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKJ1", "type": "external" } ], "mass": 81297.0, "length": 721, "protein_name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "gene_name": "pcif1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "pcif1", "gene_names_refseq": "", "protein_names_uniprotkb": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; 2.1.1.62; CAPAM; Cap-specific adenosine methyltransferase; Phosphorylated CTD-interacting factor 1; zCAPAM", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:553360)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;30467178", "class_list": "", "function": "Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs (PubMed:30467178)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IDC3;Q568T9", "ec_number_list": [ { "id": "2.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.62", "type": "external" } ], "go_molecular_function": "GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity;GO:1904047 S-adenosyl-L-methionine binding;GO:0099122 RNA polymerase II C-terminal domain binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0045727 positive regulation of translation;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IKJ1-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKK6-1", "uniprot_id": [ { "id": "A0A0R4IKK6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKK6", "type": "external" } ], "mass": 41072.0, "length": 359, "protein_name": "choline-phosphate cytidylyltransferase", "gene_name": "pcyt1bb", "organism": "Zebrafish", "refseq_name": "phosphate cytidylyltransferase 1B, choline b isoform X1", "refseq_ac": [ { "id": "XP_068071983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071983", "type": "external" } ], "gene_names_uniprotkb": "pcyt1bb; zgc:123291", "gene_names_refseq": "pcyt1bb; zgc:123291", "protein_names_uniprotkb": "choline-phosphate cytidylyltransferase; 2.7.7.15", "protein_names_refseq": "phosphate cytidylyltransferase 1B, choline b isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:555725)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12477932;21873635;23594743;36708962", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3K7", "ec_number_list": [ { "id": "2.7.7.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.15", "type": "external" } ], "go_molecular_function": "GO:0004105 choline-phosphate cytidylyltransferase activity;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IKK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKP7-1", "uniprot_id": [ { "id": "A0A0R4IKP7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKP7", "type": "external" } ], "mass": 44827.0, "length": 403, "protein_name": "Transmembrane protein 200A; Transmembrane protein 200B", "gene_name": "tmem200b", "organism": "Zebrafish", "refseq_name": "transmembrane protein 200A isoform X1", "refseq_ac": [ { "id": "XP_005159619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159619", "type": "external" } ], "gene_names_uniprotkb": "tmem200b", "gene_names_refseq": "tmem200b", "protein_names_uniprotkb": "Transmembrane protein 200A; Transmembrane protein 200B", "protein_names_refseq": "transmembrane protein 200A isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6M5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKP7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKQ6-1", "uniprot_id": [ { "id": "A0A0R4IKQ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKQ6", "type": "external" } ], "mass": 80425.0, "length": 719, "protein_name": "CD248 molecule, endosialin a", "gene_name": "cd248a", "organism": "Zebrafish", "refseq_name": "CD248 molecule, endosialin a precursor", "refseq_ac": [ { "id": "NP_001092698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092698", "type": "external" } ], "gene_names_uniprotkb": "cd248a; fb96b12; wu:fb96b12; zgc:162651", "gene_names_refseq": "cd248a; fb96b12; wu:fb96b12; zgc:162651", "protein_names_uniprotkb": "CD248 molecule, endosialin a", "protein_names_refseq": "CD248 molecule, endosialin a precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:323364)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;28705894;35088848;36119065", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: BC141789.1, GDQQ01014874.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 10, 2025 this sequence version replaced NP_001092698.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Cd248a and Cd248b in zebrafish participate in innate immune responses. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NDU1", "ec_number_list": [], "go_molecular_function": "GO:1990430 extracellular matrix protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0016477 cell migration;GO:0032496 response to lipopolysaccharide;GO:0045088 regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IKQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKQ9-1", "uniprot_id": [ { "id": "A0A0R4IKQ9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKQ9", "type": "external" } ], "mass": 115318.0, "length": 1062, "protein_name": "Insulin receptor substrate 2", "gene_name": "irs2b", "organism": "Zebrafish", "refseq_name": "insulin receptor substrate 2", "refseq_ac": [ { "id": "XP_700746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700746", "type": "external" } ], "gene_names_uniprotkb": "irs2b", "gene_names_refseq": "irs2b", "protein_names_uniprotkb": "Insulin receptor substrate 2", "protein_names_refseq": "insulin receptor substrate 2", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:572001); (R-DRE-109704); (R-DRE-112399); (R-DRE-112412); (R-DRE-1257604); (R-DRE-1266695); (R-DRE-198203); (R-DRE-5673001); (R-DRE-6811558); (R-DRE-74713); (R-DRE-74749); (R-DRE-8853659); (R-DRE-9006335); (R-DRE-9027276)", "pathway_count": 14, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_700746.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TBY1", "ec_number_list": [], "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0035591 signaling adaptor activity;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0008286 insulin receptor signaling pathway;GO:0051050 positive regulation of transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKQ9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKR8-1", "uniprot_id": [ { "id": "A0A0R4IKR8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKR8", "type": "external" } ], "mass": 120031.0, "length": 1065, "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "hip1rb", "organism": "Zebrafish", "refseq_name": "huntingtin interacting protein 1 related b", "refseq_ac": [ { "id": "NP_001077034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077034", "type": "external" } ], "gene_names_uniprotkb": "hip1rb; hip1r; zgc:158784", "gene_names_refseq": "hip1rb; hip1r; zgc:158784", "protein_names_uniprotkb": "Huntingtin-interacting protein 1-related protein", "protein_names_refseq": "huntingtin interacting protein 1 related b", "tax_id": 7955, "disease": "", "pathway": " (dre:562138)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26377317;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC133158.1, SRR26395062.1102440.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On May 13, 2016 this sequence version replaced NP_001077034.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NDT8", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0051015 actin filament binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0030659 cytoplasmic vesicle membrane;GO:0030136 clathrin-coated vesicle;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030100 regulation of endocytosis;GO:0061024 membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IKR8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKS9-1", "uniprot_id": [ { "id": "A0A0R4IKS9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKS9", "type": "external" } ], "mass": 51334.0, "length": 463, "protein_name": "B box and SPRY domain-containing protein; B-box and SPRY domain-containing", "gene_name": "bspry", "organism": "Zebrafish", "refseq_name": "B box and SPRY domain-containing protein", "refseq_ac": [ { "id": "NP_001313364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313364", "type": "external" } ], "gene_names_uniprotkb": "bspry; si:dkey-170o10.4", "gene_names_refseq": "bspry; si:dkey-170o10.4", "protein_names_uniprotkb": "B box and SPRY domain-containing protein; B-box and SPRY domain-containing", "protein_names_refseq": "B box and SPRY domain-containing protein; trim104", "tax_id": 7955, "disease": "", "pathway": " (dre:559377)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15520368;21789205;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01027761.1, GFIL01002591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505382, SAMEA4476739 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and CT643861.2. On May 18, 2016 this sequence version replaced XP_687804.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8L2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4IKS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKT5-1", "uniprot_id": [ { "id": "A0A0R4IKT5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKT5", "type": "external" } ], "mass": 223440.0, "length": 2022, "protein_name": "Autophagy-related protein 2 homolog A; Si:ch73-45o6.2", "gene_name": "atg2a", "organism": "Zebrafish", "refseq_name": "autophagy-related protein 2 homolog A", "refseq_ac": [ { "id": "XP_009306033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009306033", "type": "external" } ], "gene_names_uniprotkb": "atg2a", "gene_names_refseq": "atg2a", "protein_names_uniprotkb": "Autophagy-related protein 2 homolog A; Si:ch73-45o6.2", "protein_names_refseq": "autophagy-related protein 2 homolog A", "tax_id": 7955, "disease": "", "pathway": " (dre:101883461)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BEZ0", "ec_number_list": [ { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0006869 lipid transport;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKT5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKU3-1", "uniprot_id": [ { "id": "RECK_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKU3", "type": "external" } ], "mass": 105521.0, "length": 955, "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "gene_name": "reck", "organism": "Zebrafish", "refseq_name": "reversion-inducing cysteine-rich protein with Kazal motifs precursor", "refseq_ac": [ { "id": "NP_001410782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410782", "type": "external" } ], "gene_names_uniprotkb": "reck", "gene_names_refseq": "reck; si:ch1073-416f3.1", "protein_names_uniprotkb": "Reversion-inducing cysteine-rich protein with Kazal motifs", "protein_names_refseq": "nft; no food for thought; reversion-inducing cysteine-rich protein with Kazal motifs precursor; sdp; zmp:0000000982", "tax_id": 7955, "disease": "", "pathway": " (dre:100334698)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "22296847;23594743;26051822;26657775;27979830;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01004860.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB772271.1, GDQH01004860.1 and CT682995.2. On Aug 17, 2023 this sequence version replaced XP_009295477.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Functions together with adgra2 to enable brain endothelial cells to selectively respond to Wnt7 signals (wnt7a or wnt7b) (PubMed:26051822, PubMed:26657775). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PubMed:26051822, PubMed:26657775). Acts as a Wnt7-specific coactivator of canonical Wnt signaling by decoding Wnt ligands: acts by interacting specifically with the disordered linker region of Wnt7, thereby conferring ligand selectivity for Wnt7. Adgra2 is then required to deliver reck-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex. Also acts as a serine protease inhibitor (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]; Study found reck function to be both necessary for dorsal root ganglia formation and sufficient to rescue the sensory deprived phenotype, [RefSeq, PubMed]; The GPI-anchored MMP inhibitor Reck and the adhesion GPCR Gpr124 are integral components of the Wnt7a/Wnt7b-specific signaling complex required for brain angiogenesis and dorsal root ganglia neurogenesis. Publication Status: Online-Only, [RefSeq, PubMed]; The results of these zebrafish and Human Umbilical Vein Endothelial Cell studies suggest that Reck promotes Vascular Endothelial Growth Factor signaling in contexts other than embryonic cerebrovascular development. Erratum:[Development. 2016 Mar 15;143(6):1055. doi: 10.1242/dev.136507. PMID: 26980794], [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A0A2R8QDM9;F1QWT7", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0015026 coreceptor activity;GO:0004866 endopeptidase inhibitor activity;GO:0008191 metalloendopeptidase inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:1990909 Wnt signalosome;GO:0098552 side of membrane", "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0016055 Wnt signaling pathway;GO:0001955 blood vessel maturation;GO:0060070 canonical Wnt signaling pathway;GO:0060828 regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IKU3-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.0000000000000001.0100000011000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IKW1-1", "uniprot_id": [ { "id": "A0A0R4IKW1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IKW1", "type": "external" } ], "mass": 24569.0, "length": 209, "protein_name": "RING finger protein 207-like isoform X1; Ring finger protein 207a", "gene_name": "rnf207a", "organism": "Zebrafish", "refseq_name": "RING finger protein 207-like isoform X2", "refseq_ac": [ { "id": "XP_005169403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169403", "type": "external" } ], "gene_names_uniprotkb": "rnf207a", "gene_names_refseq": "rnf207a", "protein_names_uniprotkb": "RING finger protein 207-like isoform X1; Ring finger protein 207a", "protein_names_refseq": "RING finger protein 207-like isoform X2", "tax_id": 7955, "disease": "", "pathway": " (dre:100001767)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGM6", "ec_number_list": [], "go_molecular_function": "GO:0030544 Hsp70 protein binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IKW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL04-1", "uniprot_id": [ { "id": "A0A0R4IL04_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL04", "type": "external" } ], "mass": 50424.0, "length": 450, "protein_name": "Cyclic AMP-responsive element-binding protein 5", "gene_name": "creb5a", "organism": "Zebrafish", "refseq_name": "cyclic AMP-responsive element-binding protein 5", "refseq_ac": [ { "id": "XP_009292464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292464", "type": "external" } ], "gene_names_uniprotkb": "creb5a", "gene_names_refseq": "creb5a", "protein_names_uniprotkb": "Cyclic AMP-responsive element-binding protein 5", "protein_names_refseq": "cyclic AMP-responsive element-binding protein 5", "tax_id": 7955, "disease": "", "pathway": " (dre:101886947)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to the cAMP response element and activates transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ASI3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0035497 cAMP response element binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IL04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL07-1", "uniprot_id": [ { "id": "A0A0R4IL07_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL07", "type": "external" } ], "mass": 58632.0, "length": 507, "protein_name": "Bloodthirsty-related gene family, member 5", "gene_name": "btr05", "organism": "Zebrafish", "refseq_name": "bloodthirsty-related gene family, member 5 isoform X1", "refseq_ac": [ { "id": "XP_021333400", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333400", "type": "external" } ], "gene_names_uniprotkb": "btr05; zgc:172119", "gene_names_refseq": "btr05; zgc:172119", "protein_names_uniprotkb": "Bloodthirsty-related gene family, member 5", "protein_names_refseq": "bloodthirsty-related gene family, member 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:794264); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "19196451;21789205;23594743;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QHI2", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4IL07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL08-1", "uniprot_id": [ { "id": "A0A0R4IL08_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL08", "type": "external" } ], "mass": 44720.0, "length": 397, "protein_name": "Si:ch73-173h19.3; Uncharacterized protein LOC563864 precursor", "gene_name": "si:ch73-173h19.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC563864 precursor", "refseq_ac": [ { "id": "NP_001103991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103991", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-173h19.3", "gene_names_refseq": "si:ch73-173h19.3", "protein_names_uniprotkb": "Si:ch73-173h19.3; Uncharacterized protein LOC563864 precursor", "protein_names_refseq": "EGF-containing fibulin-like extracellular matrix protein 1-like; uncharacterized protein LOC563864 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:563864)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18973681;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.13801542.1 [ECO:0000332] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Nov 16, 2007 this sequence version replaced XP_692315.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFF0", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IL08-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL24-1", "uniprot_id": [ { "id": "A0A0R4IL24_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL24", "type": "external" } ], "mass": 87235.0, "length": 762, "protein_name": "Coiled-coil alpha-helical rod protein 1", "gene_name": "si:dkeyp-20g2.1", "organism": "Zebrafish", "refseq_name": "coiled-coil alpha-helical rod protein 1 isoform X1", "refseq_ac": [ { "id": "XP_695620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695620", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-20g2.1; si:dkeyp-20g2.3", "gene_names_refseq": "si:dkeyp-20g2.1", "protein_names_uniprotkb": "Coiled-coil alpha-helical rod protein 1; Alpha-helical coiled-coil rod protein", "protein_names_refseq": "coiled-coil alpha-helical rod protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:567236)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_695620.1. COMPLETENESS: full length., [RefSeq]; May be a regulator of keratinocyte proliferation or differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFF4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005814 centriole", "go_biological_process": "GO:0030154 cell differentiation;GO:0006611 protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IL24-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL29-1", "uniprot_id": [ { "id": "A0A0R4IL29_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL29", "type": "external" } ], "mass": 48288.0, "length": 417, "protein_name": "Calreticulin", "gene_name": "calr3b", "organism": "Zebrafish", "refseq_name": "calreticulin 3b precursor", "refseq_ac": [ { "id": "NP_958873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958873", "type": "external" } ], "gene_names_uniprotkb": "calr3b; calr3; calrl; id:ibd1087; wu:fc59g10", "gene_names_refseq": "calr3b; calr3; calrl; id:ibd1087; wu:fc59g10", "protein_names_uniprotkb": "Calreticulin", "protein_names_refseq": "calreticulin 3b precursor; calreticulin like", "tax_id": 7955, "disease": "", "pathway": " (dre:321315)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "23014190;23594743;23615277;24019943;27068748;27189481;27716741;29471808", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01002926.1, GDQQ01000357.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505376, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1, EH579061.1 and EH602296.1. On Jun 19, 2015 this sequence version replaced NP_958873.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PCH6", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane;GO:0033018 sarcoplasmic reticulum lumen;GO:0060473 cortical granule", "go_biological_process": "GO:0006457 protein folding;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0R4IL29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL52-1", "uniprot_id": [ { "id": "A0A0R4IL52_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL52", "type": "external" } ], "mass": 39663.0, "length": 356, "protein_name": "Si:dkey-207b20.2", "gene_name": "si:dkey-207b20.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-207b20.2", "refseq_ac": [ { "id": "XP_005155970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155970", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-207b20.2", "gene_names_refseq": "si:dkey-207b20.2", "protein_names_uniprotkb": "Si:dkey-207b20.2", "protein_names_refseq": "uncharacterized protein si:dkey-207b20.2", "tax_id": 7955, "disease": "", "pathway": " (dre:101882168)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B2T6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4IL52-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL71-1", "uniprot_id": [ { "id": "A0A0R4IL71_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL71", "type": "external" } ], "mass": 115533.0, "length": 998, "protein_name": "Insulin-degrading enzyme", "gene_name": "ide", "organism": "Zebrafish", "refseq_name": "insulin-degrading enzyme", "refseq_ac": [ { "id": "NP_001082994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082994", "type": "external" } ], "gene_names_uniprotkb": "ide; CH211-129M12.3-001; CH211-129M12.3; zgc:162603", "gene_names_refseq": "ide; zgc:162603", "protein_names_uniprotkb": "Insulin-degrading enzyme; 3.4.24.56; Insulin protease; Insulysin", "protein_names_refseq": "insulin-degrading enzyme; insulysin", "tax_id": 7955, "disease": "diabetic encephalopathy (Disease Ontology:DOID:0050850); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:561390); (R-DRE-5689880); (R-DRE-77387)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "18065431;23594743;24714733;26469318;26963759;27189481;30061596;30721868;31154177;33524730;35295584", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01003509.1, BC139607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX005050.6. On or before Jun 24, 2024 this sequence version replaced XP_005169584.1, NP_001082994.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B8JI45", "ec_number_list": [ { "id": "3.4.24.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.56", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.29", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" } ], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005782 peroxisomal matrix;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:1990798 pancreas regeneration;GO:0050435 amyloid-beta metabolic process;GO:0042447 hormone catabolic process;GO:0043171 peptide catabolic process;GO:0031018 endocrine pancreas development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4IL71-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4IL77-1", "uniprot_id": [ { "id": "A0A0R4IL77_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4IL77", "type": "external" } ], "mass": 64062.0, "length": 574, "protein_name": "Protein RRNAD1; Ribosomal RNA adenine dimethylase domain containing 1", "gene_name": "mettl25b", "organism": "Zebrafish", "refseq_name": "methyltransferase-like protein 25B", "refseq_ac": [ { "id": "NP_001082903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082903", "type": "external" } ], "gene_names_uniprotkb": "mettl25b; rrnad1; zgc:110579", "gene_names_refseq": "mettl25b; rrnad1; zgc:110579", "protein_names_uniprotkb": "Protein RRNAD1; Ribosomal RNA adenine dimethylase domain containing 1", "protein_names_refseq": "methyltransferase-like protein 25B; ribosomal RNA adenine dimethylase domain containing 1", "tax_id": 7955, "disease": "", "pathway": " (dre:791981)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12477932;23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA4476730, SAMEA4476731 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000016.1. On or before Apr 15, 2008 this sequence version replaced NP_001018584.1, XP_001331168.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NE81", "ec_number_list": [], "go_molecular_function": "GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4IL77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILA2-1", "uniprot_id": [ { "id": "A0A0R4ILA2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILA2", "type": "external" } ], "mass": 89734.0, "length": 799, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "ntrk2b", "organism": "Zebrafish", "refseq_name": "neurotrophic tyrosine kinase, receptor, type 2b precursor", "refseq_ac": [ { "id": "NP_001184090", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184090", "type": "external" } ], "gene_names_uniprotkb": "ntrk2b; si:ch211-220b11.1; si:ch73-270f14.4; trkB2", "gene_names_refseq": "ntrk2b; si:ch211-220b11.1; si:ch73-270f14.4; trkB2", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "neurotrophic tyrosine kinase, receptor, type 2b precursor; neurotrophic tyrosine kinase, receptor, type 2", "tax_id": 7955, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); developmental and epileptic encephalopathy 58 (Disease Ontology:DOID:0080285); Alzheimer's disease (Disease Ontology:DOID:10652); morbid obesity (Disease Ontology:DOID:11981); autistic disorder (Disease Ontology:DOID:12849); major depressive disorder (Disease Ontology:DOID:1470); bipolar disorder (Disease Ontology:DOID:3312); cerebral infarction (Disease Ontology:DOID:3526); schizophrenia (Disease Ontology:DOID:5419); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dre:570240)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16109975;16448862;16825768;20162349;23594743;34168553;34650032;35628418;35737348;36417881;7781913", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.4822944.1, SRR32588729.8339385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476729, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001184090.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB in zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUU1", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0060175 brain-derived neurotrophic factor receptor activity;GO:0005524 ATP binding;GO:0048403 brain-derived neurotrophic factor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex;GO:0010008 endosome membrane", "go_biological_process": "GO:1990416 cellular response to brain-derived neurotrophic factor stimulus;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0010976 positive regulation of neuron projection development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4ILA2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILA8-1", "uniprot_id": [ { "id": "A0A0R4ILA8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILA8", "type": "external" } ], "mass": 47883.0, "length": 427, "protein_name": "26S proteasome regulatory subunit 6A isoform X1; Proteasome 26S subunit, ATPase 3", "gene_name": "psmc3", "organism": "Zebrafish", "refseq_name": "26S proteasome regulatory subunit 6A isoform X1", "refseq_ac": [ { "id": "XP_005169019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169019", "type": "external" } ], "gene_names_uniprotkb": "psmc3; wu:fb39a02; zgc:86713", "gene_names_refseq": "psmc3; wu:fb39a02; zgc:86713", "protein_names_uniprotkb": "26S proteasome regulatory subunit 6A isoform X1; Proteasome 26S subunit, ATPase 3", "protein_names_refseq": "26S proteasome regulatory subunit 6A isoform X1", "tax_id": 7955, "disease": "sensorineural hearing loss (Disease Ontology:DOID:10003); cataract (Disease Ontology:DOID:83)", "pathway": " (dre:321947); (R-DRE-1169091); (R-DRE-1234176); (R-DRE-1236978); (R-DRE-174084); (R-DRE-174154); (R-DRE-174178); (R-DRE-174184); (R-DRE-187577); (R-DRE-195253); (R-DRE-2467813); (R-DRE-349425); (R-DRE-350562); (R-DRE-382556); (R-DRE-450408); (R-DRE-4608870); (R-DRE-4641257); (R-DRE-4641258); (R-DRE-5358346); (R-DRE-5610780); (R-DRE-5610785); (R-DRE-5632684); (R-DRE-5658442); (R-DRE-5668541); (R-DRE-5687128); (R-DRE-5689603); (R-DRE-5689880); (R-DRE-6798695); (R-DRE-68867); (R-DRE-68949); (R-DRE-69017); (R-DRE-69481); (R-DRE-69601); (R-DRE-75815); (R-DRE-8852276); (R-DRE-8854050); (R-DRE-8939236); (R-DRE-8939902); (R-DRE-8941858); (R-DRE-8948751); (R-DRE-8951664); (R-DRE-9755511); (R-DRE-9762114); (R-DRE-9766229); (R-DRE-983168); (R-DRE-9907900); (R-DRE-9929491); (R-DRE-9932298); (R-DRE-9954709)", "pathway_count": 49, "publication_count": 11, "publication_id_list": "11116086;15194198;16109975;20353558;23594743;26469318;27974833;28252024;30631305;32500975;33391408", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BG93", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0036402 proteasome-activating activity", "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000502 proteasome complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002088 lens development in camera-type eye;GO:0060879 semicircular canal fusion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0R4ILA8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILB2-1", "uniprot_id": [ { "id": "FLC2A_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILB2", "type": "external" } ], "mass": 51800.0, "length": 470, "protein_name": "Choline/ethanolamine transporter flvcr2a", "gene_name": "flvcr2a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "flvcr2a; Mfsd7c-a", "gene_names_refseq": "", "protein_names_uniprotkb": "Choline/ethanolamine transporter flvcr2a; Feline leukemia virus subgroup C receptor-related protein 2 homolog A; Heme transporter flvcr2a; Major facilitator superfamily domain containing 7C-a", "protein_names_refseq": "", "tax_id": 7955, "disease": "proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Disease Ontology:DOID:0111666)", "pathway": " (dre:565210)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;38302740", "class_list": "", "function": "Choline uniporter that specifically mediates choline uptake at the blood-brain-barrier (PubMed:38302740). Responsible for the majority of choline uptake across the blood-brain-barrier from the circulation into the brain (By similarity). Choline, a nutrient critical for brain development, is a precursor of phosphatidylcholine, as well as betaine (By similarity). Also mediates transport of ethanolamine (By similarity). Choline and ethanolamine transport is not coupled with proton transport and is exclusively driven by the choline gradient across the plasma membrane (By similarity). Also acts as a heme b transporter (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TF83", "ec_number_list": [], "go_molecular_function": "GO:0015232 heme transmembrane transporter activity;GO:0020037 heme binding;GO:0015220 choline transmembrane transporter activity;GO:0034228 ethanolamine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0097037 heme export;GO:0150104 transport across blood-brain barrier", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0R4ILB2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILD9-1", "uniprot_id": [ { "id": "A0A0R4ILD9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILD9", "type": "external" } ], "mass": 33572.0, "length": 302, "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "eif2b1", "organism": "Zebrafish", "refseq_name": "translation initiation factor eIF2B subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_009300311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300311", "type": "external" } ], "gene_names_uniprotkb": "eif2b1; zgc:86660", "gene_names_refseq": "eif2b1; zgc:86660", "protein_names_uniprotkb": "Translation initiation factor eIF2B subunit alpha; eIF2B GDP-GTP exchange factor subunit alpha", "protein_names_refseq": "translation initiation factor eIF2B subunit alpha isoform X1", "tax_id": 7955, "disease": "leukoencephalopathy with vanishing white matter (Disease Ontology:DOID:0060868); leukoencephalopathy with vanishing white matter 1 (Disease Ontology:DOID:0070374)", "pathway": " (dre:415150); (R-DRE-72731)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "12477932;21873635;23594743;33300869;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ASX8", "ec_number_list": [], "go_molecular_function": "GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005851 eukaryotic translation initiation factor 2B complex", "go_biological_process": "GO:0006413 translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0R4ILD9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILE1-1", "uniprot_id": [ { "id": "A0A0R4ILE1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILE1", "type": "external" } ], "mass": 275071.0, "length": 2461, "protein_name": "Si:ch73-347e22.4", "gene_name": "si:ch73-347e22.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-347e22.4", "refseq_ac": [ { "id": "XP_003200604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200604", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-347e22.4", "gene_names_refseq": "si:ch73-347e22.4", "protein_names_uniprotkb": "Si:ch73-347e22.4", "protein_names_refseq": "uncharacterized protein si:ch73-347e22.4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200604.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RJA9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ILE1-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILF4-1", "uniprot_id": [ { "id": "A0A0R4ILF4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILF4", "type": "external" } ], "mass": 3456.0, "length": 25, "protein_name": "60S ribosomal protein L41", "gene_name": "fa91g07", "organism": "Zebrafish", "refseq_name": "si:dkey-151g10.6", "refseq_ac": [ { "id": "NP_001410330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410330", "type": "external" } ], "gene_names_uniprotkb": "fa91g07; fj23d10; rpl41; wu:fa91g07; wu:fj23d10", "gene_names_refseq": "fa91g07; fj23d10; rpl41; si:dkey-151g10.6; wu:fa91g07; wu:fj23d10", "protein_names_uniprotkb": "60S ribosomal protein L41", "protein_names_refseq": "Ribosomal protein L41; si:dkey-151g10.6", "tax_id": 7955, "disease": "", "pathway": " (dre:335588)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "20039754;23594743;36653451", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CB357331.1, EH525351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4ILF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "uniprot_id": [ { "id": "A0A0R4ILG2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILG2", "type": "external" } ], "mass": 6525.0, "length": 59, "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "organism": "Zebrafish", "refseq_name": "sodium/potassium-transporting ATPase subunit gamma", "refseq_ac": [ { "id": "NP_001268850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268850", "type": "external" } ], "gene_names_uniprotkb": "fxyd2; si:ch211-139a5.9", "gene_names_refseq": "fxyd2; si:ch211-139a5.9", "protein_names_uniprotkb": "FXYD domain-containing ion transport regulator", "protein_names_refseq": "sodium/potassium-transporting ATPase subunit gamma", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-5578775); (R-DRE-936837)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "21423371;23594743;26469318;30417250;31113326", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH609708.1, EH592204.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505381, SAMEA3505387 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P519", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:1903278 positive regulation of sodium ion export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0R4ILG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILH0-1", "uniprot_id": [ { "id": "A0A0R4ILH0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILH0", "type": "external" } ], "mass": 17482.0, "length": 162, "protein_name": "Interferon-induced transmembrane protein 3; Si:dkey-33i11.9; Synapse differentiation-inducing gene protein 1-like", "gene_name": "si:dkey-33i11.9", "organism": "Zebrafish", "refseq_name": "synapse differentiation-inducing gene protein 1-like", "refseq_ac": [ { "id": "NP_001373279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373279", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-33i11.9", "gene_names_refseq": "si:dkey-33i11.9", "protein_names_uniprotkb": "Interferon-induced transmembrane protein 3; Si:dkey-33i11.9; Synapse differentiation-inducing gene protein 1-like", "protein_names_refseq": "synapse differentiation-inducing gene protein 1-like", "tax_id": 7955, "disease": "", "pathway": " (dre:569467)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15520368;23594743;24683187", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01002408.1, GDQQ01004469.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505386 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Aug 21, 2020 this sequence version replaced XP_009290911.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B201", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4ILH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILH2-1", "uniprot_id": [ { "id": "A0A0R4ILH2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILH2", "type": "external" } ], "mass": 42853.0, "length": 370, "protein_name": "Epoxide hydrolase 4", "gene_name": "ephx4", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ephx4", "gene_names_refseq": "", "protein_names_uniprotkb": "Epoxide hydrolase 4", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100331939)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PF14", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0004301 epoxide hydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ILH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILK3-1", "uniprot_id": [ { "id": "A0A0R4ILK3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILK3", "type": "external" } ], "mass": 97557.0, "length": 890, "protein_name": "Rho GTPase-activating protein 11A", "gene_name": "arhgap11a", "organism": "Zebrafish", "refseq_name": "rho GTPase-activating protein 11A isoform 1", "refseq_ac": [ { "id": "NP_001180468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180468", "type": "external" } ], "gene_names_uniprotkb": "arhgap11a; wu:fc02e04; wu:fc55g06; wu:fe01b01; zgc:77004", "gene_names_refseq": "arhgap11a; wu:fc02e04; wu:fc55g06; wu:fe01b01; zgc:77004", "protein_names_uniprotkb": "Rho GTPase-activating protein 11A", "protein_names_refseq": "rho GTPase-activating protein 11A isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:406608); (R-DRE-8980692)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "17703193;19221799;23594743;27189481;29420541;31560986;34986794;36229674;37079685", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01022902.1, SRR32588718.11651781.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 25, 2025 this sequence version replaced NP_001180468.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NX98", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0R4ILK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILM9-1", "uniprot_id": [ { "id": "A0A0R4ILM9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILM9", "type": "external" } ], "mass": 251968.0, "length": 2234, "protein_name": "Nucleolar pre-ribosomal-associated protein 1; URB1 ribosome biogenesis homolog", "gene_name": "urb1", "organism": "Zebrafish", "refseq_name": "nucleolar pre-ribosomal-associated protein 1", "refseq_ac": [ { "id": "NP_001313374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313374", "type": "external" } ], "gene_names_uniprotkb": "urb1; mp:zf637-1-000544", "gene_names_refseq": "mp:zf637-1-000544; urb1", "protein_names_uniprotkb": "Nucleolar pre-ribosomal-associated protein 1; URB1 ribosome biogenesis homolog", "protein_names_refseq": "nucleolar pre-ribosomal-associated protein 1; zf637-1-000544", "tax_id": 7955, "disease": "", "pathway": " (dre:100536352)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16109975;23594743;26469318;29246861;36403304;36890225", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007496.1, GFIL01019182.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001313374.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance., [RefSeq, PubMed]; Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7Y6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0048565 digestive tract development;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0090069 regulation of ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0R4ILM9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILN1-1", "uniprot_id": [ { "id": "A0A0R4ILN1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILN1", "type": "external" } ], "mass": 94074.0, "length": 859, "protein_name": "Coiled-coil and C2 domain-containing protein 1B", "gene_name": "cc2d1b", "organism": "Zebrafish", "refseq_name": "coiled-coil and C2 domain-containing protein 1B isoform X1", "refseq_ac": [ { "id": "XP_005171255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171255", "type": "external" } ], "gene_names_uniprotkb": "cc2d1b", "gene_names_refseq": "cc2d1b", "protein_names_uniprotkb": "Coiled-coil and C2 domain-containing protein 1B", "protein_names_refseq": "coiled-coil and C2 domain-containing protein 1B isoform X1", "tax_id": 7955, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (dre:563720); (R-DRE-9668328)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IRG6;A0A0R4IXS1;A0A8M2BIW6", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0R4ILN1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILT6-1", "uniprot_id": [ { "id": "A0A0R4ILT6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILT6", "type": "external" } ], "mass": 11441.0, "length": 105, "protein_name": "Cocaine- and amphetamine-regulated transcript protein-like; Cocaine- and amphetamine-regulated transcript-like precursor; Cocaine-and amphetamine-regulated transcript protein-like; Si:ch73-380l10.2", "gene_name": "cartl", "organism": "Zebrafish", "refseq_name": "cocaine- and amphetamine-regulated transcript-like precursor", "refseq_ac": [ { "id": "NP_001373336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373336", "type": "external" } ], "gene_names_uniprotkb": "cartl; si:ch73-380l10.2", "gene_names_refseq": "cartl; si:ch73-380l10.2", "protein_names_uniprotkb": "Cocaine- and amphetamine-regulated transcript protein-like; Cocaine- and amphetamine-regulated transcript-like precursor; Cocaine-and amphetamine-regulated transcript protein-like; Si:ch73-380l10.2", "protein_names_refseq": "cocaine- and amphetamine-regulated transcript-like precursor; cocaine-and amphetamine-regulated transcript protein-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100329270)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;27189481;30125742;32652159", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH608295.1, EH590817.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 21, 2020 this sequence version replaced XP_017212746.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A387J5F7", "ec_number_list": [], "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0008343 adult feeding behavior;GO:0009267 cellular response to starvation;GO:0032099 negative regulation of appetite", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0R4ILT6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4ILX8-1", "uniprot_id": [ { "id": "A0A0R4ILX8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0R4ILX8", "type": "external" } ], "mass": 54677.0, "length": 490, "protein_name": "Noelin-2b precursor; Olfactomedin 2b", "gene_name": "olfm2b", "organism": "Zebrafish", "refseq_name": "noelin-2b", "refseq_ac": [ { "id": "NP_998425", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998425", "type": "external" } ], "gene_names_uniprotkb": "olfm2b; olfm2l; zgc:85900", "gene_names_refseq": "olfm2b; olfm2l; zgc:85900", "protein_names_uniprotkb": "Noelin-2b precursor; Olfactomedin 2b", "protein_names_refseq": "noelin-2b", "tax_id": 7955, "disease": "", "pathway": " (dre:406544)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "20851470;23594743;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC068422.1, GFIL01029104.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA4476744 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 13, 2015 this sequence version replaced NP_998425.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1TT10", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0045202 synapse", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0R4ILX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true } ]