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CG42793; CG43203; Dmel\\CG43203; Dmel_CG43203", "gene_names_refseq": "CG42793; CG43203; Dmel\\CG43203; noncoding_17732", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43203-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43203)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K7I1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7I2-1", "uniprot_id": [ { "id": "A0A0B4K7I2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7I2", "type": "external" } ], "mass": 60967.0, "length": 552, "protein_name": "Smooth, isoform T", "gene_name": "sm", "organism": "Fruit fly", "refseq_name": "smooth, isoform T", "refseq_ac": [ { "id": "NP_001246428", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246428", "type": "external" } ], "gene_names_uniprotkb": "sm; 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CG43267; Dmel_CG43267", "gene_names_refseq": "CG43267; Dmel\\CG43267", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43267-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43267)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K7I9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7J2-1", "uniprot_id": [ { "id": "RBP2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7J2", "type": "external" } ], "mass": 298931.0, "length": 2718, "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Nup358", "organism": "Fruit fly", "refseq_name": "nucleoporin 358kD, isoform B", "refseq_ac": [ { "id": "NP_001247302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247302", "type": "external" } ], "gene_names_uniprotkb": "Nup358; CG11856; RanBP2", "gene_names_refseq": "CG11856; Dmel\\CG11856; NUP358; Nup358; Q9VBU7_DROME; RanBP2; dmRanBP; nup358; ranbp2", "protein_names_uniprotkb": "E3 SUMO-protein ligase RanBP2; 2.3.2.-; 358 kDa nucleoporin; Nuclear pore complex protein Nup358", "protein_names_refseq": "CG11856-PB; Nup358-PB; nucleoporin 358kD, isoform B; nucleoporin 358", "tax_id": 7227, "disease": "inflammatory myofibroblastic tumor (Disease Ontology:DOID:0050905); brain disease (Disease Ontology:DOID:936); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (dme:Dmel_CG11856); (R-DME-159227); (R-DME-159230); (R-DME-159231); (R-DME-159236); (R-DME-3108214); (R-DME-3301854); (R-DME-3371453); (R-DME-4085377); (R-DME-4551638); (R-DME-4615885)", "pathway_count": 11, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;14729961;17682050;20547758;27979731;29735528;31626769;40245499", "class_list": "", "function": "E3 SUMO-protein ligase (By similarity). Component of the nuclear pore complex (NPC), a complex required for trafficking across the nuclear envelope (PubMed:17682050). Required for nuclear import of nuclear localization signal (NLS)-containing proteins in an importin alpha/importin beta-dependent manner, but also for the nuclear import of specific proteins such as phosphorylated Mad or the sesquiterpenoid juvenile hormone receptor Met as part of the juvenile hormone signal transduction pathway (PubMed:17682050, PubMed:27979731). Plays a role in nuclear mRNA export by recruiting the mRNA transport complex composed of Nxt1 and sbr/Nxf1 to the NPC (PubMed:14729961). Essential during germline development for transposon silencing and piRNA biogenesis probably by regulating piwi localization to the nucleus (PubMed:29735528). During oogenesis, required to form granules that modulate the biogenesis of annulate lamellae containing nuclear pore complex components (PubMed:31626769)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D3DMF2;Q8SWV7;Q9VBU7", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019789 SUMO transferase activity", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005737 cytoplasm;GO:0005642 annulate lamellae", "go_biological_process": "GO:0046833 positive regulation of RNA export from nucleus;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0032880 regulation of protein localization;GO:0007281 germ cell development", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "A0A0B4K7J2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7J3-1", "uniprot_id": [ { "id": "A0A0B4K7J3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7J3", "type": "external" } ], "mass": 65862.0, "length": 582, "protein_name": "receptor protein serine/threonine kinase", "gene_name": "sax", "organism": "Fruit fly", "refseq_name": "saxophone, isoform C", "refseq_ac": [ { "id": "NP_001246193", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246193", "type": "external" } ], "gene_names_uniprotkb": "sax; Bkr43E; Brk43E; CG1891; Dmel\\CG1891; Dmel_CG1891; SAX; STK-B; Sax; Sa", "gene_names_refseq": "Bkr43E; Brk43E; CG1891; Dmel\\CG1891; SAX; STK-B; Sax; Sa; sax", "protein_names_uniprotkb": "receptor protein serine/threonine kinase; 2.7.11.30", "protein_names_refseq": "CG1891-PC; sax-PC; saxophone, isoform C; saxophone", "tax_id": 7227, "disease": "arteriovenous malformations of the brain (Disease Ontology:DOID:0060688); primary open angle glaucoma (Disease Ontology:DOID:1070); arteriovenous malformation (Disease Ontology:DOID:11294); hereditary hemorrhagic telangiectasia (Disease Ontology:DOID:1270); severe pre-eclampsia (Disease Ontology:DOID:13129); fibrodysplasia ossificans progressiva (Disease Ontology:DOID:13374); exfoliation syndrome (Disease Ontology:DOID:13641); primary angle-closure glaucoma (Disease Ontology:DOID:1405); pancreatic cancer (Disease Ontology:DOID:1793); transient cerebral ischemia (Disease Ontology:DOID:224); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (dme:Dmel_CG1891)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;32369743;8044838", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004675 transmembrane receptor protein serine/threonine kinase activity;GO:0005025 transforming growth factor beta receptor activity, type I;GO:0046332 SMAD binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070724 BMP receptor complex;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0030154 cell differentiation;GO:0050829 defense response to Gram-negative bacterium;GO:0071363 cellular response to growth factor stimulus;GO:0030509 BMP signaling pathway;GO:0009953 dorsal/ventral pattern formation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "A0A0B4K7J3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7J4-1", "uniprot_id": [ { "id": "A0A0B4K7J4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7J4", "type": "external" } ], "mass": 140435.0, "length": 1279, "protein_name": "Glial cell line-derived neurotrophic family receptor-like, isoform E", "gene_name": "Gfrl", "organism": "Fruit fly", "refseq_name": "glial cell line-derived neurotrophic family receptor-like, isoform E", "refseq_ac": [ { "id": "NP_001247206", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247206", "type": "external" } ], "gene_names_uniprotkb": "Gfrl; BcDNA:GH26447; CG17203; CG17204; CG17205; CG17208; CG33518; CG34118; CG34119; CG42401; CG42625; CG42801; CG43224; CG4342; DmGfrl; Dmel\\CG43224; Dmel_CG43224; dGFRLAb; dGFRLA; mun", "gene_names_refseq": "BcDNA:GH26447; CG17203; CG17204; CG17205; CG17208; CG33518; CG34118; CG34119; CG42401; CG42625; CG42801; CG43224; CG4342; DmGfrl; Dmel\\CG43224; Gfrl; dGFRLAb; dGFRLA; mun", "protein_names_uniprotkb": "Glial cell line-derived neurotrophic family receptor-like, isoform E", "protein_names_refseq": "CG43224-PE; GDNF Receptor-like; Gfrl-PE; glial cell line-derived neurotrophic family receptor-like, isoform E; munin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43224); (R-DME-8853659)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050839 cell adhesion molecule binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K7J4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7K5-1", "uniprot_id": [ { "id": "A0A0B4K7K5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7K5", "type": "external" } ], "mass": 14255.0, "length": 127, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG43393", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001246456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246456", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43393; CG43393; Dmel_CG43393", "gene_names_refseq": "CG43393; Dmel\\CG43393", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43393-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43393)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K7K5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "uniprot_id": [ { "id": "A0A0B4K7K9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7K9", "type": "external" } ], "mass": 255301.0, "length": 2238, "protein_name": "Bruchpilot, isoform J", "gene_name": "brp", "organism": "Fruit fly", "refseq_name": "bruchpilot, isoform J", "refseq_ac": [ { "id": "NP_001246228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246228", "type": "external" } ], "gene_names_uniprotkb": "brp; BRP; Brp; CG12932; CG12933; CG1931; CG30336; CG30337; CG34146; CG42344; Cast; Dmel\\CG42344; Dmel_CG42344; MAbnc82; Mabnc82; NC82; Nc82; mAb nc82; mAbnc82; nc-82; nc82", "gene_names_refseq": "BRP; Brp; Bruchpilot; CG12932; CG12933; CG1931; CG30336; CG30337; CG34146; CG42344; Cast; Dmel\\CG42344; MAbnc82; Mabnc82; NC82; Nc82; brp; mAb nc82; mAbnc82; nc-82; nc82", "protein_names_uniprotkb": "Bruchpilot, isoform J", "protein_names_refseq": "CG42344-PJ; brp-PJ; bruchpilot, isoform J; bruchpilot; brunchpilot; burchpilot; monoclonal antibody nc82", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42344)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0098882 structural constituent of presynaptic active zone", "go_cellular_component": "GO:0030424 axon;GO:0048786 presynaptic active zone;GO:0048788 cytoskeleton of presynaptic active zone;GO:0098831 presynaptic active zone cytoplasmic component;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0048789 cytoskeletal matrix organization at active zone;GO:0048790 maintenance of presynaptic active zone structure;GO:0007274 neuromuscular synaptic transmission;GO:0008344 adult locomotory behavior;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "A0A0B4K7K9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7L9-1", "uniprot_id": [ { "id": "A0A0B4K7L9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7L9", "type": "external" } ], "mass": 4585.0, "length": 40, "protein_name": "Uncharacterized protein, isoform A; Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG43397", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_001246249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246249", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43397; CG43397; Dmel_CG43397", "gene_names_refseq": "CG43397; Dmel\\CG43397", "protein_names_uniprotkb": "Uncharacterized protein, isoform A; Uncharacterized protein, isoform B", "protein_names_refseq": "CG43397-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43397)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K7L9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7M5-1", "uniprot_id": [ { "id": "A0A0B4K7M5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7M5", "type": "external" } ], "mass": 9608.0, "length": 83, "protein_name": "Heterochromatin protein 1L chromoshadow domain", "gene_name": "HP1Lcsd", "organism": "Fruit fly", "refseq_name": "heterochromatin protein 1L chromoshadow domain", "refseq_ac": [ { "id": "NP_001246478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246478", "type": "external" } ], "gene_names_uniprotkb": "HP1Lcsd; 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CG43200; Dmel_CG43200; nc_5744.a", "gene_names_refseq": "CG43200; Dmel\\CG43200; nc_5744.a", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43200-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43200)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K848-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K857-1", "uniprot_id": [ { "id": "A0A0B4K857_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K857", "type": "external" } ], "mass": 10333.0, "length": 90, "protein_name": "TIL domain-containing protein", "gene_name": "chr2R_15474834_15475129.0", "organism": "Fruit fly", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "chr2R_15474834_15475129.0; CG42878; Dmel\\CG42878; Dmel_CG42878", "gene_names_refseq": "", "protein_names_uniprotkb": "TIL domain-containing protein", "protein_names_refseq": "", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K857-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K859-1", "uniprot_id": [ { "id": "NU188_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K859", "type": "external" } ], "mass": 213609.0, "length": 1866, "protein_name": "Nucleoporin Nup188", "gene_name": "Nup188", "organism": "Fruit fly", "refseq_name": "nucleoporin 188kDa, isoform C", "refseq_ac": [ { "id": "NP_001246283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246283", "type": "external" } ], "gene_names_uniprotkb": "Nup188; 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CG43647; Dmel_CG43647; lincRNA.258; mlncRNA42E5-1", "gene_names_refseq": "CG43647; Dmel\\CG43647; lincRNA.258; mlncRNA42E5-1", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43647-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43647)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KED5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KEE4-1", "uniprot_id": [ { "id": "KOI_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4", "type": "external" } ], "mass": 109725.0, "length": 965, "protein_name": "Klaroid protein", "gene_name": "koi", "organism": "Fruit fly", "refseq_name": "klaroid, isoform A", "refseq_ac": [ { "id": "NP_001260738", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260738", "type": "external" } ], "gene_names_uniprotkb": "koi; 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The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0070979 protein K11-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KEY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KEZ2-1", "uniprot_id": [ { "id": "A0A0B4KEZ2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KEZ2", "type": "external" } ], "mass": 78287.0, "length": 757, "protein_name": "Nervy, isoform D", "gene_name": "nvy", "organism": "Fruit fly", "refseq_name": "nervy, isoform D", "refseq_ac": [ { "id": "NP_001261166", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261166", "type": "external" } ], "gene_names_uniprotkb": "nvy; CG3385; Dmel\\CG3385; Dmel_CG3385; Nvy", "gene_names_refseq": "CG3385; Dmel\\CG3385; Nvy; nvy", "protein_names_uniprotkb": "Nervy, isoform D", "protein_names_refseq": "CG3385-PD; nervy, isoform D; nervy; nvy-PD", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3385)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016020 membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0007411 axon guidance;GO:0008407 chaeta morphogenesis;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KEZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KEZ3-1", "uniprot_id": [ { "id": "A0A0B4KEZ3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KEZ3", "type": "external" } ], "mass": 20712.0, "length": 188, "protein_name": "C-type lectin domain-containing protein", "gene_name": "CR14499", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001261072", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261072", "type": "external" } ], "gene_names_uniprotkb": "CR14499; CG14499; Dmel\\CG14499; Dmel_CG14499", "gene_names_refseq": "CG14499; CR14499; Dmel\\CG14499", "protein_names_uniprotkb": "C-type lectin domain-containing protein", "protein_names_refseq": "CG14499-PC; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14499)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0038187 pattern recognition receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KEZ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KF06-1", "uniprot_id": [ { "id": "A0A0B4KF06_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KF06", "type": "external" } ], "mass": 118793.0, "length": 1055, "protein_name": "Valine--tRNA ligase", "gene_name": "ValRS", "organism": "Fruit fly", "refseq_name": "Valyl-tRNA synthetase, isoform C", "refseq_ac": [ { "id": "NP_001260946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260946", "type": "external" } ], "gene_names_uniprotkb": "ValRS; Aats-val; BEST:LD45671; CG4062; Dmel\\CG4062; Dmel_CG4062; VRS; aaRS(Val); aats-val; dVARS; l(2)03531; l(2)rI255; ld45671", "gene_names_refseq": "Aats-val; BEST:LD45671; CG4062; Dmel\\CG4062; VARS; VRS; ValRS; aaRS(Val); aats-val; dVARS; l(2)03531; l(2)rI255; ld45671", "protein_names_uniprotkb": "Valine--tRNA ligase; 6.1.1.9; Valyl-tRNA synthetase", "protein_names_refseq": "CG4062-PC; ValRS-PC; Valyl-tRNA synthetase, isoform C", "tax_id": 7227, "disease": "myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); combined oxidative phosphorylation deficiency 20 (Disease Ontology:DOID:0111478); mitochondrial metabolism disease (Disease Ontology:DOID:700); mitochondrial encephalomyopathy (Disease Ontology:DOID:890)", "pathway": " (dme:Dmel_CG4062)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.9", "type": "external" } ], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004832 valine-tRNA ligase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006438 valyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KF06-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KF09-1", "uniprot_id": [ { "id": "A0A0B4KF09_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KF09", "type": "external" } ], "mass": 37074.0, "length": 340, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG43710", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001261105", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261105", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43710; CG43710; Dmel_CG43710", "gene_names_refseq": "CG43710; Dmel\\CG43710", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43710-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43710)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KF09-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KF12-1", "uniprot_id": [ { "id": "A0A0B4KF12_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KF12", "type": "external" } ], "mass": 65863.0, "length": 604, "protein_name": "Diuretic hormone 31 receptor, isoform C", "gene_name": "Dh31-R", "organism": "Fruit fly", "refseq_name": "diuretic hormone 31 receptor, isoform C", "refseq_ac": [ { "id": "NP_001260951", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260951", "type": "external" } ], "gene_names_uniprotkb": "Dh31-R; CG17043; CG17415; CG32843; DH31-R1; DH31-R; DH31R; DH31; Dh31-R1; Dh31R; Dh31r; DmeCG32843; Dmel\\CG32843; Dmel_CG32843; anon-WO0170980.136; anon-WO0170980.137; dh31-R1", "gene_names_refseq": "CG17043; CG17415; CG32843; DH31-R1; DH31-R; DH31R; DH31; Dh31-R1; Dh31-R; Dh31R; Dh31r; DmeCG32843; Dmel\\CG32843; anon-WO0170980.136; anon-WO0170980.137; dh31-R1", "protein_names_uniprotkb": "Diuretic hormone 31 receptor, isoform C", "protein_names_refseq": "CG32843-PC; Calcitonin-like diuretic hormone receptor; DH31 receptor; DH31-receptor; DH[[31]] receptor; Dh31-R-PC; diuretic hormone 31 receptor 1; diuretic hormone 31 receptor, isoform C", "tax_id": 7227, "disease": "hereditary lymphedema (Disease Ontology:DOID:0050580); osteoporosis (Disease Ontology:DOID:11476); brain infarction (Disease Ontology:DOID:3454)", "pathway": " (dme:Dmel_CG32843); (R-DME-419812)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004948 calcitonin receptor activity;GO:0008188 neuropeptide receptor activity;GO:0008036 diuretic hormone receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KF12-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KF15-1", "uniprot_id": [ { "id": "A0A0B4KF15_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KF15", "type": "external" } ], "mass": 162601.0, "length": 1472, "protein_name": "Mangetout, isoform G", "gene_name": "mtt", "organism": "Fruit fly", "refseq_name": "mangetout, isoform G", "refseq_ac": [ { "id": "NP_001260806", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260806", "type": "external" } ], "gene_names_uniprotkb": "mtt; CG18447; CG30361-RC; CG30361; CG8692; DmGluBR; DmGluRB; DmXR; Dmel\\CG30361; Dmel_CG30361; Glu-RB; GluRB; anon-WO0170980.4; anon-WO0170980.5; mXr", "gene_names_refseq": "CG18447; CG30361; CG8692; DmGluBR; DmGluRB; DmXR; Dmel\\CG30361; Glu-RB; GluRB; Mtt; anon-WO0170980.4; anon-WO0170980.5; mXr; mtt", "protein_names_uniprotkb": "Mangetout, isoform G", "protein_names_refseq": "CG30361-PG; DmX receptor; mXr; mangetout, isoform G; mtt-PG", "tax_id": 7227, "disease": "congenital stationary night blindness 1B (Disease Ontology:DOID:0110865)", "pathway": " (dme:Dmel_CG30361)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0008343 adult feeding behavior;GO:0017085 response to insecticide", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KF15-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KF19-1", "uniprot_id": [ { "id": "A0A0B4KF19_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KF19", "type": "external" } ], "mass": 82596.0, "length": 746, "protein_name": "Uncharacterized protein, isoform C", "gene_name": "Cables1", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001260958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260958", "type": "external" } ], "gene_names_uniprotkb": "Cables1; 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Reduction in Cnn dots 1, isoform E", "gene_name": "Rcd1", "organism": "Fruit fly", "refseq_name": "reduction in Cnn dots 1, isoform E", "refseq_ac": [ { "id": "NP_001260963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260963", "type": "external" } ], "gene_names_uniprotkb": "Rcd1; CG8233-RA; CG8233; Dmel\\CG8233; Dmel_CG8233; NSL3; Nsl3; cg8233", "gene_names_refseq": "CG8233; Dmel\\CG8233; NSL3; Nsl3; Rcd1; cg8233", "protein_names_uniprotkb": "3.-.-.-; Reduction in Cnn dots 1, isoform E", "protein_names_refseq": "CG8233-PE; Rcd1-PE; non-specific lethal 3; reduction in Cnn dots 1, isoform E; reduction in Cnn dots 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8233); (R-DME-3214847); (R-DME-9772755)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.4.1.255", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.255", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0044545 NSL complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007099 centriole replication", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "A0A0B4KF25-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KF28-1", "uniprot_id": [ { "id": "A0A0B4KF28_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KF28", "type": "external" } ], "mass": 60911.0, "length": 562, "protein_name": "Partner of paired, isoform B", "gene_name": "Ppa", "organism": "Fruit fly", "refseq_name": "partner of paired, isoform B", "refseq_ac": [ { "id": "NP_001261138", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261138", "type": "external" } ], "gene_names_uniprotkb": "Ppa; 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BEST:SD06302; CG7734; Dmel\\CG7734; Dmel_CG7734; EP(2)2359; EP2359; SD06302; SHN; Schnurri; Shn; l(2)04738; quo", "gene_names_refseq": "BEST:SD06302; CG7734; Dmel\\CG7734; EP(2)2359; EP2359; SD06302; SHN; Schnurri; Shn; l(2)04738; quo; shn", "protein_names_uniprotkb": "Schnurri, isoform F", "protein_names_refseq": "CG7734-PF; quo vadis; schnurri, isoform F; schnurri; shn-PF; umnitza", "tax_id": 7227, "disease": "juvenile polyposis syndrome (Disease Ontology:DOID:0050787); autosomal dominant intellectual developmental disorder 43 (Disease Ontology:DOID:0070073); intellectual disability (Disease Ontology:DOID:1059); Alzheimer's disease (Disease Ontology:DOID:10652); asthma (Disease Ontology:DOID:2841); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG7734)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0090571 RNA polymerase II transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007494 midgut development;GO:0030509 BMP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFC0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFC4-1", "uniprot_id": [ { "id": "A0A0B4KFC4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4", "type": "external" } ], "mass": 73129.0, "length": 680, "protein_name": "Ribbon, isoform C", "gene_name": "rib", "organism": "Fruit fly", "refseq_name": "ribbon, isoform C", "refseq_ac": [ { "id": "NP_001261085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261085", "type": "external" } ], "gene_names_uniprotkb": "rib; CG7230; Dmel\\CG7230; Dmel_CG7230; RIB; Rib; fus1; gene 5", "gene_names_refseq": "CG7230; Dmel\\CG7230; RIB; Rib; fus1; gene 5; rib", "protein_names_uniprotkb": "Ribbon, isoform C", "protein_names_refseq": "CG7230-PC; SGP cluster fusion defects 1; rib-PC; ribbon, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7230)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;11731471;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0007417 central nervous system development;GO:0007010 cytoskeleton organization;GO:0007391 dorsal closure", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KFC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFC9-1", "uniprot_id": [ { "id": "A0A0B4KFC9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFC9", "type": "external" } ], "mass": 98662.0, "length": 881, "protein_name": "FXNA-like protease", "gene_name": "Dmel\\CG10073", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001261090", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261090", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10073; CG10073-RA; CG10073; Dmel_CG10073", "gene_names_refseq": "CG10073; Dmel\\CG10073; FBgn0034440", "protein_names_uniprotkb": "FXNA-like protease", "protein_names_refseq": "CG10073-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (dme:Dmel_CG10073)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008235 metalloexopeptidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFC9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFD0-1", "uniprot_id": [ { "id": "A0A0B4KFD0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFD0", "type": "external" } ], "mass": 5763.0, "length": 53, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44227", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262382", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44227; CG44227; Dmel_CG44227", "gene_names_refseq": "CG44227; Dmel\\CG44227", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44227-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44227)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KFD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFD1-1", "uniprot_id": [ { "id": "A0A0B4KFD1_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFD1", "type": "external" } ], "mass": 530554.0, "length": 4752, "protein_name": "LDL receptor protein 1, isoform F", "gene_name": "LRP1", "organism": "Fruit fly", "refseq_name": "LDL receptor protein 1, isoform F", "refseq_ac": [ { "id": "NP_001260800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260800", "type": "external" } ], "gene_names_uniprotkb": "LRP1; CG30368; CG33087; CG8706; CT9297; Dm CG33087; Dmel\\CG33087; Dmel_CG33087; LDLR; Lrp1; lrp1", "gene_names_refseq": "CG30368; CG33087; CG8706; CT9297; Dm CG33087; Dmel\\CG33087; LRP-1; LRP1; Lrp1; dmLRP1; lrp1", "protein_names_uniprotkb": "LDL receptor protein 1, isoform F", "protein_names_refseq": "CG33087-PF; LDL receptor protein 1, isoform F; LDL receptor protein; LDL receptor-related protein 1; LDL-receptor-related protein 1; LRP1-PF", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); omphalocele (Disease Ontology:DOID:0060327); keratosis pilaris atrophicans (Disease Ontology:DOID:0080751); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); gastroschisis (Disease Ontology:DOID:11044); sciatic neuropathy (Disease Ontology:DOID:11446); alcoholic hepatitis (Disease Ontology:DOID:12351); lung cancer (Disease Ontology:DOID:1324); alcohol use disorder (Disease Ontology:DOID:1574); epilepsy (Disease Ontology:DOID:1826); melanoma (Disease Ontology:DOID:1909); colon cancer (Disease Ontology:DOID:219); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); gallbladder cancer (Disease Ontology:DOID:3121); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); prostate carcinoma in situ (Disease Ontology:DOID:8634); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": " (dme:Dmel_CG33087)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005041 low-density lipoprotein particle receptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0043235 receptor complex;GO:0012505 endomembrane system", "go_biological_process": "GO:0032368 regulation of lipid transport;GO:1902667 regulation of axon guidance;GO:0006897 endocytosis;GO:1903064 positive regulation of reverse cholesterol transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KFD1-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFD8-1", "uniprot_id": [ { "id": "A0A0B4KFD8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFD8", "type": "external" } ], "mass": 28814.0, "length": 256, "protein_name": "48 related 1, isoform B", "gene_name": "Fer1", "organism": "Fruit fly", "refseq_name": "48 related 1, isoform B", "refseq_ac": [ { "id": "NP_001262334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262334", "type": "external" } ], "gene_names_uniprotkb": "Fer1; BcDNA:RH30329; CG10066; CG14611; CG33323-RA; CG33323; Dmel\\CG33323; Dmel_CG33323; bHLHa30; fer1", "gene_names_refseq": "BcDNA:RH30329; CG10066; CG14611; CG33323; Dmel\\CG33323; Fer1; bHLHa30; fer1", "protein_names_uniprotkb": "48 related 1, isoform B", "protein_names_refseq": "48 related 1, isoform B; CG33323-PB; Fer1-PB; ferritin 1", "tax_id": 7227, "disease": "pancreatic agenesis 2 (Disease Ontology:DOID:0060988)", "pathway": " (dme:Dmel_CG33323)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0032502 developmental process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFD8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFD9-1", "uniprot_id": [ { "id": "A0A0B4KFD9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFD9", "type": "external" } ], "mass": 29335.0, "length": 284, "protein_name": "Uncharacterized protein", "gene_name": "CG15226", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001261107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261107", "type": "external" } ], "gene_names_uniprotkb": "CG15226; CG43666; Dmel\\CG43666; Dmel_CG43666", "gene_names_refseq": "CG15226; CG43666; Dmel\\CG43666", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43666-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43666)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KFD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFE4-1", "uniprot_id": [ { "id": "A0A0B4KFE4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFE4", "type": "external" } ], "mass": 81815.0, "length": 728, "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "Acsl", "organism": "Fruit fly", "refseq_name": "Acyl-CoA synthetase long-chain, isoform J", "refseq_ac": [ { "id": "NP_001260810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260810", "type": "external" } ], "gene_names_uniprotkb": "Acsl; 7447; ACSL1; ACSL3; CG8732; Dmel\\CG8732; Dmel_CG8732; FACS; FCS; anon-WO0172774.173; dAcsl; dFAC; l(2)05847; l(2)44DEa; l(2)7447; l(2)SH0465; l(2)SH2 0465; l(2)k05304", "gene_names_refseq": "7447; ACSL1; ACSL3/4; ACSL3; ACS; Acsl; CG8732; Dmel\\CG8732; FACS; FCS; acsl; anon-WO0172774.173; dAcsl; dFAC; l(2)05847; l(2)44DEa; l(2)7447; l(2)SH0465; l(2)SH2 0465; l(2)k05304", "protein_names_uniprotkb": "long-chain-fatty-acid--CoA ligase; 6.2.1.3", "protein_names_refseq": "Acsl-PJ; Acyl-CoA synthetase long-chain, isoform J; Acyl-CoAsynthetase long-chain; CG8732-PJ; Long-chain acyl-CoA synthetase; fatty acyl CoA synthetase; fatty acyl coenzyme A (CoA) synthetase; fatty acyl-CoA synthetase; lethal (2) 44DEa; lethal (2) SH0465", "tax_id": 7227, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); non-syndromic X-linked intellectual disability 63 (Disease Ontology:DOID:0112050); prostate cancer (Disease Ontology:DOID:10283); intellectual disability (Disease Ontology:DOID:1059); lung cancer (Disease Ontology:DOID:1324); Sjogren-Larsson syndrome (Disease Ontology:DOID:14501); breast cancer (Disease Ontology:DOID:1612); asthma (Disease Ontology:DOID:2841)", "pathway": " (dme:Dmel_CG8732); (R-DME-434313); (R-DME-75876)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0004467 long-chain fatty acid-CoA ligase activity;GO:0090433 palmitoyl-CoA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0030424 axon;GO:0045202 synapse;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0007268 chemical synaptic transmission;GO:0035282 segmentation;GO:0010890 positive regulation of triglyceride storage;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFE4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFE8-1", "uniprot_id": [ { "id": "A0A0B4KFE8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFE8", "type": "external" } ], "mass": 95009.0, "length": 855, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG10321", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001261124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261124", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10321; CG10321; Dmel_CG10321", "gene_names_refseq": "CG10321; Dmel\\CG10321", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG10321-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10321)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFF2-1", "uniprot_id": [ { "id": "A0A0B4KFF2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFF2", "type": "external" } ], "mass": 53497.0, "length": 474, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG43742", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001261130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261130", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43742; CG43742; Dmel_CG43742; SP251", "gene_names_refseq": "CG43742; Dmel\\CG43742; SP251", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "CG43742-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43742)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KFF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFF9-1", "uniprot_id": [ { "id": "A0A0B4KFF9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFF9", "type": "external" } ], "mass": 322800.0, "length": 2990, "protein_name": "Jitterbug, isoform N", "gene_name": "jbug", "organism": "Fruit fly", "refseq_name": "jitterbug, isoform N", "refseq_ac": [ { "id": "NP_001261140", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261140", "type": "external" } ], "gene_names_uniprotkb": "jbug; 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CG4630; Dmel_CG4630", "gene_names_refseq": "CG4630; Dmel\\CG4630", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG4630-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); myelodysplastic syndrome (Disease Ontology:DOID:0050908); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); systemic primary carnitine deficiency disease (Disease Ontology:DOID:14365); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); congestive heart failure (Disease Ontology:DOID:6000); inherited metabolic disorder (Disease Ontology:DOID:655); rheumatoid arthritis (Disease Ontology:DOID:7148); Crohn's disease (Disease Ontology:DOID:8778)", "pathway": " (dme:Dmel_CG4630); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFK6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFL3-1", "uniprot_id": [ { "id": "A0A0B4KFL3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFL3", "type": "external" } ], "mass": 66877.0, "length": 605, "protein_name": "Katanin p60 ATPase-containing subunit A1", "gene_name": "Kat60", "organism": "Fruit fly", "refseq_name": "katanin 60, isoform B", "refseq_ac": [ { "id": "NP_001262276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262276", "type": "external" } ], "gene_names_uniprotkb": "Kat60; CG10229; Dm-Kat60; DmCG10229; Dmel\\CG10229; Dmel_CG10229; KATNA1; Kat-60; Katanin-60; kat-60; kat60; katanin-60-RA; katanin-60; katanin60-dm", "gene_names_refseq": "CG10229; Dm-Kat60; DmCG10229; Dmel\\CG10229; Kat-60; Kat60; Katanin-60; kat-60; kat60; katanin-60; katanin60-dm", "protein_names_uniprotkb": "Katanin p60 ATPase-containing subunit A1; 5.6.1.1; Katanin p60 subunit A1; p60 katanin", "protein_names_refseq": "CG10229-PB; Kat60-PB; Katanin-60; katanin 60, isoform B; katanin 60; katanin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10229)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0017022 myosin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005938 cell cortex", "go_biological_process": "GO:0051013 microtubule severing;GO:0016358 dendrite development;GO:0051301 cell division;GO:0030336 negative regulation of cell migration;GO:0007019 microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFN3-1", "uniprot_id": [ { "id": "A0A0B4KFN3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFN3", "type": "external" } ], "mass": 103437.0, "length": 950, "protein_name": "Glucose transporter 4 enhancer factor, isoform G", "gene_name": "Glut4EF", "organism": "Fruit fly", "refseq_name": "glucose transporter 4 enhancer factor, isoform G", "refseq_ac": [ { "id": "NP_001262443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262443", "type": "external" } ], "gene_names_uniprotkb": "Glut4EF; BcDNA:GH25505; BcDNA:GM06804; BcDNA:RE66512; BcDNA:RH63124; CG11676; CG12802; CG12804; CG12805; CG32469; CG33975; CG34360; CG43757; D-Glut4EF; Dmel\\CG34360; Dmel_CG34360; Glut4; Glut; stretch", "gene_names_refseq": "BcDNA:GH25505; BcDNA:GM06804; BcDNA:RE66512; BcDNA:RH63124; CG11676; CG12802; CG12804; CG12805; CG32469; CG33975; CG34360; CG43757; D-Glut4EF; Dmel\\CG34360; Glut4EF; Glut; stretch", "protein_names_uniprotkb": "Glucose transporter 4 enhancer factor, isoform G", "protein_names_refseq": "BcDNA:GH25505; BcDNA:GM06804; CG34360-PG; Glut4EF-PG; glucose transporter 4 enhancer factor, isoform G; stretched out", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34360)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18245850;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KFN3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFN6-1", "uniprot_id": [ { "id": "A0A0B4KFN6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFN6", "type": "external" } ], "mass": 139703.0, "length": 1265, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "Dmel\\CG6923", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001262484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262484", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG6923; CG6923-RB; CG6923; Dmel_CG6923", "gene_names_refseq": "CG6923; Dmel\\CG6923", "protein_names_uniprotkb": "Uncharacterized protein, isoform D", "protein_names_refseq": "CG6923-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6923)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFN6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFP2-1", "uniprot_id": [ { "id": "A0A0B4KFP2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFP2", "type": "external" } ], "mass": 228532.0, "length": 2097, "protein_name": "Enhancer of polycomb-like protein", "gene_name": "E(Pc)", "organism": "Fruit fly", "refseq_name": "enhancer of polycomb, isoform E", "refseq_ac": [ { "id": "NP_001260897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260897", "type": "external" } ], "gene_names_uniprotkb": "E(Pc); CG7776; Dmel\\CG7776; Dmel_CG7776; E(PC); GH05739; GH14582; III; anon-48Ac; e(Pc); e(pc); l(2)28-28-12", "gene_names_refseq": "CG7776; Dmel\\CG7776; E(PC); E(Pc); E(pc); EN2-2; GH05739; GH14582; III; anon-48Ac; e(Pc); e(pc); l(2)28-28-12", "protein_names_uniprotkb": "Enhancer of polycomb-like protein", "protein_names_refseq": "CG7776-PE; E(Pc)-PE; enhancer of NA9 2-2; enhancer of polycomb, isoform E; enhancer of polycomb; transcript group III", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7776); (R-DME-8953750)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000123 histone acetyltransferase complex;GO:0005700 polytene chromosome;GO:0032777 piccolo histone acetyltransferase complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0070983 dendrite guidance", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0B4KFP2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFQ3-1", "uniprot_id": [ { "id": "A0A0B4KFQ3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFQ3", "type": "external" } ], "mass": 32946.0, "length": 306, "protein_name": "DNAation factor-related protein 1, isoform B", "gene_name": "Drep1", "organism": "Fruit fly", "refseq_name": "DNA fragmentation factor-related protein 1, isoform B", "refseq_ac": [ { "id": "NP_001260909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260909", "type": "external" } ], "gene_names_uniprotkb": "Drep1; CG8357; DREP-1; DREP1; Dmel\\CG8357; Dmel_CG8357; Drep-1; ICAD; Rep1; dICAD; drep1", "gene_names_refseq": "CG8357; DREP-1/dICAD; DREP-1; DREP1; Dmel\\CG8357; Drep-1; Drep1; ICAD/DREP-1; ICAD; Rep1; dICAD; drep1", "protein_names_uniprotkb": "DNAation factor-related protein 1, isoform B", "protein_names_refseq": "CG8357-PB; DFF45-related protein-1; DNA fragmentation factor-related protein 1, isoform B; Drep1-PB; Rep1; inhibitor of CAD", "tax_id": 7227, "disease": "familial partial lipodystrophy type 5 (Disease Ontology:DOID:0070203); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG8357); (R-DME-140342); (R-DME-8964572)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060703 deoxyribonuclease inhibitor activity;GO:0140311 protein sequestering activity", "go_cellular_component": "", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0042981 regulation of apoptotic process;GO:0006309 apoptotic DNA fragmentation;GO:0045476 nurse cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFQ3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFQ5-1", "uniprot_id": [ { "id": "A0A0B4KFQ5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFQ5", "type": "external" } ], "mass": 36255.0, "length": 316, "protein_name": "Tetraspanin-33", "gene_name": "Tsp86D", "organism": "Fruit fly", "refseq_name": "tetraspanin 86D, isoform C", "refseq_ac": [ { "id": "NP_001262468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262468", "type": "external" } ], "gene_names_uniprotkb": "Tsp86D; CG4591; Dm.Tsp86D; Dmel\\CG4591; Dmel_CG4591; tsp86D", "gene_names_refseq": "CG4591; Dm.Tsp86D; Dmel\\CG4591; Tsp86D; tsp86D", "protein_names_uniprotkb": "Tetraspanin-33", "protein_names_refseq": "CG4591-PC; Tetraspanin86D; Tsp86D-PC; tetraspanin 86D, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4591); (R-DME-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0016020 membrane;GO:0046930 pore complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0072659 protein localization to plasma membrane;GO:0045747 positive regulation of Notch signaling pathway;GO:0051604 protein maturation;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFR5-1", "uniprot_id": [ { "id": "A0A0B4KFR5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFR5", "type": "external" } ], "mass": 218815.0, "length": 1957, "protein_name": "3.6.1.3; Kinesin heavy chain 73, isoform E", "gene_name": "Khc-73", "organism": "Fruit fly", "refseq_name": "kinesin heavy chain 73, isoform E", "refseq_ac": [ { "id": "NP_001261000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261000", "type": "external" } ], "gene_names_uniprotkb": "Khc-73; B; CG8183; DmKIN73; DmKin73; DmKlp73; Dmel\\CG8183; Dmel_CG8183; KHC-73; KIF 13A; KLP73; Khc73; Kin73; Kinesin-73; anon-EST:fe3C9; khc-73", "gene_names_refseq": "CG8183; DmKIN73; DmKin73; DmKlp73; Dmel\\CG8183; KHC-73; KIF 13A; KIF13A/B; KLP73; Khc 73; Khc-73; Khc73; Kin73; Kinesin-73; anon-EST:fe3C9; khc-73; khc73", "protein_names_uniprotkb": "3.6.1.3; Kinesin heavy chain 73, isoform E", "protein_names_refseq": "CG8183-PE; Khc-73-PE; Kinesin-3; Kinesin-73; Kinesin3B; anon-fast-evolving-3C9; kinesin heavy chain 73, isoform E; kinesin heavy-chain 73", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8183)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0051294 establishment of spindle orientation;GO:0050803 regulation of synapse structure or activity;GO:0007018 microtubule-based movement;GO:0008104 protein localization;GO:0090328 regulation of olfactory learning", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KFR5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFR9-1", "uniprot_id": [ { "id": "A0A0B4KFR9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFR9", "type": "external" } ], "mass": 14966.0, "length": 132, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG43254", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001262346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262346", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43254; CG43254; Dmel_CG43254; lincRNA.715", "gene_names_refseq": "CG43254; Dmel\\CG43254; lincRNA.715", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG43254-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43254)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KFR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFS5-1", "uniprot_id": [ { "id": "A0A0B4KFS5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFS5", "type": "external" } ], "mass": 113336.0, "length": 991, "protein_name": "1.14.11.16; 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CG9813; Dmel_CG9813; ORE-7", "gene_names_refseq": "CG9813; Dmel\\CG9813; ORE-7", "protein_names_uniprotkb": "Uncharacterized protein, isoform G", "protein_names_refseq": "CG9813-PG; uncharacterized protein, isoform G", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9813)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFZ1-1", "uniprot_id": [ { "id": "A0A0B4KFZ1_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1", "type": "external" } ], "mass": 32447.0, "length": 297, "protein_name": "Entomoglyceroporin 4, isoform F", "gene_name": "Eglp4", "organism": "Fruit fly", "refseq_name": "entomoglyceroporin 4, isoform F", "refseq_ac": [ { "id": "NP_001261154", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261154", "type": "external" } ], "gene_names_uniprotkb": "Eglp4; Aqp4019; CG4019-RC; CG4019-RD; CG4019; Dmel\\CG4019; Dmel_CG4019; Eglp 4", "gene_names_refseq": "Aqp4019; CG4019; Dmel\\CG4019; Eglp 4; Eglp4", "protein_names_uniprotkb": "Entomoglyceroporin 4, isoform F", "protein_names_refseq": "CG4019-PF; Eglp4-PF; entomoglyceroporin 4, isoform F", "tax_id": 7227, "disease": "Alpers-Huttenlocher syndrome (Disease Ontology:DOID:0080122); megalencephalic leukoencephalopathy with subcortical cysts (Disease Ontology:DOID:0080315); transverse myelitis (Disease Ontology:DOID:0080743); nephrogenic diabetes insipidus type 2 (Disease Ontology:DOID:0081061); cataract 15 multiple types (Disease Ontology:DOID:0110251); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); Bothnian type palmoplantar keratoderma (Disease Ontology:DOID:0111707); dry eye syndrome (Disease Ontology:DOID:10140); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); hydrocephalus (Disease Ontology:DOID:10908); optic neuritis (Disease Ontology:DOID:1210); primary biliary cholangitis (Disease Ontology:DOID:12236); malaria (Disease Ontology:DOID:12365); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); uveitis (Disease Ontology:DOID:13141); blindness (Disease Ontology:DOID:1432); retinal vein occlusion (Disease Ontology:DOID:1727); status epilepticus (Disease Ontology:DOID:1824); diabetic ketoacidosis (Disease Ontology:DOID:1837); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); thymoma (Disease Ontology:DOID:3275); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); temporal lobe epilepsy (Disease Ontology:DOID:3328); middle cerebral artery infarction (Disease Ontology:DOID:3525); brain edema (Disease Ontology:DOID:4724); retinal disease (Disease Ontology:DOID:5679); central pontine myelinolysis (Disease Ontology:DOID:636); cataract (Disease Ontology:DOID:83); neuromyelitis optica (Disease Ontology:DOID:8869); diabetic retinopathy (Disease Ontology:DOID:8947); cerebral amyloid angiopathy (Disease Ontology:DOID:9246); diabetes mellitus (Disease Ontology:DOID:9351); diabetes insipidus (Disease Ontology:DOID:9409); intracranial hypertension (Disease Ontology:DOID:9428); Meniere's disease (Disease Ontology:DOID:9849)", "pathway": " (dme:Dmel_CG4019); (R-DME-1237044); (R-DME-1247673); (R-DME-432040); (R-DME-432047)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015267 channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0003014 renal system process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFZ1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFZ4-1", "uniprot_id": [ { "id": "A0A0B4KFZ4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ4", "type": "external" } ], "mass": 32908.0, "length": 292, "protein_name": "Transmembrane 4 superfamily, isoform C", "gene_name": "TM4SF", "organism": "Fruit fly", "refseq_name": "transmembrane 4 superfamily, isoform C", "refseq_ac": [ { "id": "NP_001261159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261159", "type": "external" } ], "gene_names_uniprotkb": "TM4SF; CG11303; Dm.Tsp60A; Dmel\\CG11303; Dmel_CG11303; TM4SF-RA", "gene_names_refseq": "CG11303; Dm.Tsp60A; Dmel\\CG11303; TM4SF", "protein_names_uniprotkb": "Transmembrane 4 superfamily, isoform C", "protein_names_refseq": "CG11303-PC; TM4SF-PC; transmembrane 4 superfamily, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11303); (R-DME-6798695)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10191082;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KFZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG01-1", "uniprot_id": [ { "id": "A0A0B4KG01_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG01", "type": "external" } ], "mass": 78658.0, "length": 716, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "CG 13579; anon-WO0170980.151", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001261169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261169", "type": "external" } ], "gene_names_uniprotkb": "CG 13579; anon-WO0170980.151; CG 13579; CG13579; Dmel\\CG13579; Dmel_CG13579; anon-WO0170980.151; anon-WO0170980.152", "gene_names_refseq": "CG 13579; CG13579; Dmel\\CG13579; anon-WO0170980.151; anon-WO0170980.152", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG13579-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13579)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0035237 corazonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KG01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG03-1", "uniprot_id": [ { "id": "A0A0B4KG03_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG03", "type": "external" } ], "mass": 91198.0, "length": 802, "protein_name": "Flyers-cup, isoform F", "gene_name": "f-cup", "organism": "Fruit fly", "refseq_name": "flyers-cup, isoform F", "refseq_ac": [ { "id": "NP_001262544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262544", "type": "external" } ], "gene_names_uniprotkb": "f-cup; BcDNA.GH09045; BcDNA:GH09045; CG9611; Dmel\\CG9611; Dmel_CG9611", "gene_names_refseq": "BcDNA:GH09045; CG9611; Dmel\\CG9611; f-cup", "protein_names_uniprotkb": "Flyers-cup, isoform F", "protein_names_refseq": "CG9611-PF; f-cup-PF; flyers-cup, isoform F; gp150-like", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9611)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG11-1", "uniprot_id": [ { "id": "A0A0B4KG11_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG11", "type": "external" } ], "mass": 57167.0, "length": 519, "protein_name": "Sprouty-related protein with EVH-1 domain, isoform C", "gene_name": "Spred", "organism": "Fruit fly", "refseq_name": "Sprouty-related protein with EVH-1 domain, isoform C", "refseq_ac": [ { "id": "NP_001260979", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260979", "type": "external" } ], "gene_names_uniprotkb": "Spred; AE33; CG10155; Dm AE33; Dmel\\CG10155; Dmel_CG10155; Spred-RA; dSPRED; spred", "gene_names_refseq": "AE33; CG10155; Dm AE33; Dmel\\CG10155; Spred; dSPRED; spred", "protein_names_uniprotkb": "Sprouty-related protein with EVH-1 domain, isoform C", "protein_names_refseq": "CG10155-PC; Spred-PC; Sprouty-related protein with EVH-1 domain, isoform C", "tax_id": 7227, "disease": "Legius syndrome (Disease Ontology:DOID:0070484); Noonan syndrome (Disease Ontology:DOID:3490); achondroplasia (Disease Ontology:DOID:4480)", "pathway": " (dme:Dmel_CG10155); (R-DME-5658442); (R-DME-5658623)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:1902532 negative regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG11-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG18-1", "uniprot_id": [ { "id": "A0A0B4KG18_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG18", "type": "external" } ], "mass": 8526.0, "length": 72, "protein_name": "Seminal fluid protein", "gene_name": "Dmel\\CG43829", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001260989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260989", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43829; 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2.7.11.18; Stretchin-Mlck, isoform U", "gene_name": "Strn-Mlck", "organism": "Fruit fly", "refseq_name": "Stretchin-Mlck, isoform U", "refseq_ac": [ { "id": "NP_001261019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261019", "type": "external" } ], "gene_names_uniprotkb": "Strn-Mlck; 143736_at; A(225); BEST:GH22543; BcDNA:RH74685; CG15699; CG18255; CG44162; CG8304; CT41348; Dmel\\CG44162; Dmel_CG44162; MLCK-1; MLCK-2; MLCK-3; MLCK; Mlc-k; Mlck; Strn-MLCK; Strn-mlck; mlck; strn-mlck", "gene_names_refseq": "143736_at; A(225); BEST:GH22543; BcDNA:RH74685; CG15699; CG18255; CG44162; CG8304; CT41348; Dmel\\CG44162; MLCK-1; MLCK-2; MLCK-3; MLCK; Mlc-k; Mlck; Strn-MLCK; Strn-Mlck; Strn-mlck; Strn/Mlck; mlck; strn-mlck", "protein_names_uniprotkb": "2.7.11.17; 2.7.11.18; Stretchin-Mlck, isoform U", "protein_names_refseq": "225kD protein; A-band-protein-225; CG44162-PU; MLC-kinase; Stretchin-Mlck, isoform U; Strn-Mlck-PU; myosin light chain kinase; stretchin-klp; stretchin-mlck", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44162)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0004687 myosin light chain kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0097575 lateral cell cortex;GO:0032982 myosin filament", "go_biological_process": "GO:0030154 cell differentiation;GO:0009653 anatomical structure morphogenesis;GO:0035331 negative regulation of hippo signaling;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG35-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG38-1", "uniprot_id": [ { "id": "A0A0B4KG38_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG38", "type": "external" } ], "mass": 93619.0, "length": 824, "protein_name": "Semaphorin-2A", "gene_name": "Sema2b", "organism": "Fruit fly", "refseq_name": "semaphorin 2b, isoform D", "refseq_ac": [ { "id": "NP_001261024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261024", "type": "external" } ], "gene_names_uniprotkb": "Sema2b; CG30322; CG33960-RA; CG33960; CG4383; Dmel\\CG33960; Dmel_CG33960; Sema-2b; SemaIIB; sema-2b; sema2b", "gene_names_refseq": "CG30322; CG33960; CG4383; Dmel\\CG33960; Sema-2b; Sema2b; SemaIIB; sema-2b; sema2b", "protein_names_uniprotkb": "Semaphorin-2A", "protein_names_refseq": "CG33960-PD; Sema-2b; Sema2b-PD; Semaphorin-2b; semaphorin 2b, isoform D; semaphorin2b; semaphorin; semiphorin", "tax_id": 7227, "disease": "progressive myoclonus epilepsy (Disease Ontology:DOID:891)", "pathway": " (dme:Dmel_CG33960); (R-DME-416572); (R-DME-416700)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;31417095;39042673", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0070593 dendrite self-avoidance;GO:0001952 regulation of cell-matrix adhesion;GO:0071678 olfactory bulb axon guidance;GO:0016200 synaptic target attraction;GO:0070983 dendrite guidance", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "A0A0B4KG38-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG50-1", "uniprot_id": [ { "id": "A0A0B4KG50_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG50", "type": "external" } ], "mass": 550304.0, "length": 4976, "protein_name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "gene_name": "Bruce", "organism": "Fruit fly", "refseq_name": "BIR repeat containing ubiquitin-conjugating enzyme, isoform B", "refseq_ac": [ { "id": "NP_001262460", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262460", "type": "external" } ], "gene_names_uniprotkb": "Bruce; BRUCE; CG6303; Dmel\\CG6303; Dmel_CG6303; bruce; dBRUCE; dBruce; dbruce; mod86", "gene_names_refseq": "BRUCE; Bruce; CG6303; Dmel\\CG6303; bruce; dBRUCE; dBruce; dbruce; mod86", "protein_names_uniprotkb": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6; BIR repeat-containing ubiquitin-conjugating enzyme; Baculoviral IAP repeat-containing protein 6; Ubiquitin-conjugating BIR domain enzyme apollon", "protein_names_refseq": "BIR repeat containing ubiquitin-conjugating enzyme, isoform B; Bruce-PB; CG6303-PB; dbruce; mod86", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6303)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12121627;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030414 peptidase inhibitor activity;GO:0046872 metal ion binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0016020 membrane", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division;GO:0006915 apoptotic process;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KG50-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG53-1", "uniprot_id": [ { "id": "A0A0B4KG53_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG53", "type": "external" } ], "mass": 224634.0, "length": 2159, "protein_name": "Mucin related 89F, isoform B", "gene_name": "Mur89F", "organism": "Fruit fly", "refseq_name": "mucin related 89F, isoform B", "refseq_ac": [ { "id": "NP_001262662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262662", "type": "external" } ], "gene_names_uniprotkb": "Mur89F; CG4090; CT13556; Dmel\\CG4090; Dmel_CG4090", "gene_names_refseq": "CG4090; CT13556; Dmel\\CG4090; Mur89F", "protein_names_uniprotkb": "Mucin related 89F, isoform B", "protein_names_refseq": "CG4090-PB; Mur89F-PB; mucin related 89F, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4090)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005201 extracellular matrix structural constituent;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0030312 external encapsulating structure", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KG53-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG55-1", "uniprot_id": [ { "id": "A0A0B4KG55_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG55", "type": "external" } ], "mass": 10328.0, "length": 90, "protein_name": "Secreted protein", "gene_name": "Dmel\\CG44094", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262570", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44094; CG44094; Dmel_CG44094", "gene_names_refseq": "CG44094; Dmel\\CG44094", "protein_names_uniprotkb": "Secreted protein", "protein_names_refseq": "CG44094-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44094)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KG55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG57-1", "uniprot_id": [ { "id": "A0A0B4KG57_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG57", "type": "external" } ], "mass": 11419.0, "length": 99, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44090", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262667", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44090; CG44090; Dmel_CG44090", "gene_names_refseq": "CG44090; Dmel\\CG44090", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44090-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44090)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KG57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG59-1", "uniprot_id": [ { "id": "A0A0B4KG59_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG59", "type": "external" } ], "mass": 59207.0, "length": 520, "protein_name": "Serine/threonine-protein kinase receptor", "gene_name": "put", "organism": "Fruit fly", "refseq_name": "punt, isoform B", "refseq_ac": [ { "id": "NP_001262575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262575", "type": "external" } ], "gene_names_uniprotkb": "put; Act-r; Atr-II; Atr88CD; AtrII; Atr; CG7904; Dmel\\CG7904; Dmel_CG7904; PUNT; Punt; Put; STK-C; TGF-B; TGF-beta; Tgf-r; atrII; dlhC; l(3)10460; l(3)j5A5; pun", "gene_names_refseq": "Act-r; Atr-II; Atr88CD; AtrII; Atr; CG7904; Dmel\\CG7904; PUNT; Punt; Put; STK-C; TGF-B; TGF-beta; Tgf-r; atrII; dlhC; l(3)10460; l(3)j5A5; pun; put", "protein_names_uniprotkb": "Serine/threonine-protein kinase receptor; 2.7.11.30", "protein_names_refseq": "Activin-A-receptor-88CD; CG7904-PB; DPP receptor; TGF-beta-type-receptor-like; activin receptor type II; activin receptor; dorsal holes C; punt, isoform B; punt; put-PB", "tax_id": 7227, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); juvenile polyposis syndrome (Disease Ontology:DOID:0050787); visceral heterotaxy 4 (Disease Ontology:DOID:0051019); right atrial isomerism (Disease Ontology:DOID:0060856); pre-eclampsia (Disease Ontology:DOID:10591); Marfan syndrome (Disease Ontology:DOID:14323); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); Lynch syndrome (Disease Ontology:DOID:3883); Weissenbacher-Zweymuller syndrome (Disease Ontology:DOID:4258); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG7904); (R-DME-1502540); (R-DME-201451)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7697719", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005024 transforming growth factor beta receptor activity;GO:0048185 activin binding;GO:0098821 BMP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0048179 activin receptor complex;GO:0070724 BMP receptor complex", "go_biological_process": "GO:0045819 positive regulation of glycogen catabolic process;GO:0071333 cellular response to glucose stimulus;GO:0042593 glucose homeostasis;GO:0071363 cellular response to growth factor stimulus;GO:0030509 BMP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KG59-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG66-1", "uniprot_id": [ { "id": "A0A0B4KG66_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG66", "type": "external" } ], "mass": 74283.0, "length": 672, "protein_name": "2.7.11.1; 2.7.12.1; Monopolar spindle 1, isoform B", "gene_name": "Mps1", "organism": "Fruit fly", "refseq_name": "monopolar spindle 1, isoform B", "refseq_ac": [ { "id": "NP_001262677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262677", "type": "external" } ], "gene_names_uniprotkb": "Mps1; Ald; CG7643; Dmel\\CG7643; Dmel_CG7643; Mps1; Msp1; TKK; ald; dMps1; mps1", "gene_names_refseq": "Ald/Mps1; Ald; CG7643; Dmel\\CG7643; Mps1; Msp1; TKK; ald; dMps1; mps1", "protein_names_uniprotkb": "2.7.11.1; 2.7.12.1; Monopolar spindle 1, isoform B", "protein_names_refseq": "CG7643-PB; Mps1-PB; altered disjunction; monopolar spindle 1, isoform B; monopolar spindles 1", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162); bipolar disorder (Disease Ontology:DOID:3312); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG7643)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0000776 kinetochore;GO:0000940 outer kinetochore", "go_biological_process": "GO:0048133 male germ-line stem cell asymmetric division;GO:0016321 female meiosis chromosome segregation;GO:0033316 meiotic spindle assembly checkpoint signaling;GO:0007059 chromosome segregation;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG66-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG69-1", "uniprot_id": [ { "id": "A0A0B4KG69_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG69", "type": "external" } ], "mass": 101628.0, "length": 945, "protein_name": "ENL/AF9-related, isoform B", "gene_name": "ear", "organism": "Fruit fly", "refseq_name": "ENL/AF9-related, isoform B", "refseq_ac": [ { "id": "NP_001262595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262595", "type": "external" } ], "gene_names_uniprotkb": "ear; AF-9; AF9; CG4913; Dmel\\CG4913; Dmel_CG4913; ENL; Ear; TFIIF", "gene_names_refseq": "CG4913; Dmel\\CG4913; ENL/AF-9; ENL/AF9; ENL; Ear; TFIIF; dENL/AF9; ear", "protein_names_uniprotkb": "ENL/AF9-related, isoform B", "protein_names_refseq": "CG4913-PB; ENL/AF9-related, isoform B; ear-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4913)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0005669 transcription factor TFIID complex;GO:0032783 super elongation complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG69-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG70-1", "uniprot_id": [ { "id": "A0A0B4KG70_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG70", "type": "external" } ], "mass": 100996.0, "length": 922, "protein_name": "Metastasis-associated protein MTA3", "gene_name": "MTA1-like", "organism": "Fruit fly", "refseq_name": "metastasis associated 1-like, isoform D", "refseq_ac": [ { "id": "NP_001262293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262293", "type": "external" } ], "gene_names_uniprotkb": "MTA1-like; CG2244; Dmel\\CG2244; Dmel_CG2244; MTA-1like; MTA-like; MTA1; MTA; dMTA-1; dMTA1-like; dMTA; p120", "gene_names_refseq": "CG2244; Dmel\\CG2244; MTA-1like; MTA-like; MTA1-like; MTA1; MTA; dMTA-1; dMTA1-like; dMTA; p120", "protein_names_uniprotkb": "Metastasis-associated protein MTA3", "protein_names_refseq": "CG2244-PD; MTA-like; MTA1-like-PD; metastasis associated 1-like, isoform D; metastasis-associated-1-like-protein", "tax_id": 7227, "disease": "systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dme:Dmel_CG2244); (R-DME-3214815); (R-DME-3232118); (R-DME-6804758); (R-DME-8943724)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000118 histone deacetylase complex;GO:0016581 NuRD complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030261 chromosome condensation;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KG70-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG77-1", "uniprot_id": [ { "id": "A0A0B4KG77_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG77", "type": "external" } ], "mass": 24445.0, "length": 219, "protein_name": "Uncharacterized protein, isoform B; Uncharacterized protein, isoform C", "gene_name": "Dmel\\CG44013", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001262606", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262606", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44013; CG14872; CG44013; Dmel_CG44013", "gene_names_refseq": "CG14872; CG44013; Dmel\\CG44013", "protein_names_uniprotkb": "Uncharacterized protein, isoform B; Uncharacterized protein, isoform C", "protein_names_refseq": "CG44013-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44013)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG96-1", "uniprot_id": [ { "id": "A0A0B4KG96_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG96", "type": "external" } ], "mass": 92360.0, "length": 827, "protein_name": "polynucleotide adenylyltransferase", "gene_name": "hrg", "organism": "Fruit fly", "refseq_name": "hiiragi, isoform D", "refseq_ac": [ { "id": "NP_001261097", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261097", "type": "external" } ], "gene_names_uniprotkb": "hrg; CG9854; Dmel\\CG9854; Dmel_CG9854; PAP; Pap; dHrg; hrg-RA; l(2)07619; l(2)k07619", "gene_names_refseq": "CG9854; Dmel\\CG9854; Hiiragi; PAP; Pap; dHrg; hrg; l(2)07619; l(2)k07619", "protein_names_uniprotkb": "polynucleotide adenylyltransferase; 2.7.7.19", "protein_names_refseq": "CG9854-PD; Poly(A) polymerase; hiiragi, isoform D; hrg-PD; poly (A) polymerase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9854); (R-DME-73856); (R-DME-77595); (R-DME-9770562); (R-DME-9930044)", "pathway_count": 5, "publication_count": 12, "publication_id_list": "10731132;12456666;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Polymerase that creates the 3'-poly(A) tail of mRNA's., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "3.1.13.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0180011 cytosolic mRNA polyadenylation;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway;GO:0006397 mRNA processing;GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KG96-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGA3-1", "uniprot_id": [ { "id": "A0A0B4KGA3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGA3", "type": "external" } ], "mass": 48117.0, "length": 455, "protein_name": "Lethal (3) neo38, isoform L", "gene_name": "l(3)neo38", "organism": "Fruit fly", "refseq_name": "lethal (3) neo38, isoform L", "refseq_ac": [ { "id": "NP_001262485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262485", "type": "external" } ], "gene_names_uniprotkb": "l(3)neo38; BcDNA:SD16005; CG14725; CG31364; CG6930; Dmel\\CG6930; Dmel_CG6930; L(3)neo38; anon-EST:fe2F4; anon2F4; l(3)NEO38; l(3)neo38-RA; l(3)neo38-RC", "gene_names_refseq": "BcDNA:SD16005; CG14725; CG31364; CG6930; Dmel\\CG6930; L(3)neo38; anon-EST:fe2F4; anon2F4; l(3)NEO38; l(3)neo38", "protein_names_uniprotkb": "Lethal (3) neo38, isoform L", "protein_names_refseq": "CG6930-PL; anon-fast-evolving-2F4; l(3)neo38-PL; lethal (3) neo38, isoform L", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6930)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0000792 heterochromatin", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007528 neuromuscular junction development;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGA5-1", "uniprot_id": [ { "id": "A0A0B4KGA5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGA5", "type": "external" } ], "mass": 22996.0, "length": 207, "protein_name": "Uncharacterized protein", "gene_name": "CG15226", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001261108", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261108", "type": "external" } ], "gene_names_uniprotkb": "CG15226; 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CG44163; Dmel_CG44163", "gene_names_refseq": "CG44163; Dmel\\CG44163", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44163-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44163)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KGB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGB6-1", "uniprot_id": [ { "id": "A0A0B4KGB6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGB6", "type": "external" } ], "mass": 4865.0, "length": 43, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44174", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262728", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44174; CG44174; Dmel_CG44174; lincRNA.811", "gene_names_refseq": "CG44174; Dmel\\CG44174; lincRNA.811", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44174-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44174)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KGB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGD0-1", "uniprot_id": [ { "id": "A0A0B4KGD0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGD0", "type": "external" } ], "mass": 56299.0, "length": 499, "protein_name": "Regulatory protein zeste", "gene_name": "apt", "organism": "Fruit fly", "refseq_name": "apontic, isoform F", "refseq_ac": [ { "id": "NP_001261153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261153", "type": "external" } ], "gene_names_uniprotkb": "apt; 3041; APT; Apt; CG5393; Dmel\\CG5393; Dmel_CG5393; TDF; Tdp; apt-RC; l(2)03041; l(2)06369; l(2)09049; l(2)59Ea; l(2)k11531; tdf", "gene_names_refseq": "3041; APT; Apt; CG5393; Dmel\\CG5393; TDF/APT; TDF; Tdp; apt; l(2)03041; l(2)06369; l(2)09049; l(2)59Ea; l(2)k11531; tdf", "protein_names_uniprotkb": "Regulatory protein zeste", "protein_names_refseq": "CG5393-PF; apontic, isoform F; apontic; apt-PF; trachea defective; tracheae defective; tracheal defective", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5393)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. 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CG44038; Dmel_CG44038; FBgn0264830", "gene_names_refseq": "CG44038; Dmel\\CG44038; FBgn0264830", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44038-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44038)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KGD2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGD9-1", "uniprot_id": [ { "id": "A0A0B4KGD9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGD9", "type": "external" } ], "mass": 61894.0, "length": 545, "protein_name": "Uncharacterized protein, isoform C", "gene_name": "Dmel\\CG2993", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001262348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262348", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG2993; CG2993; Dmel_CG2993", "gene_names_refseq": "CG2993; Dmel\\CG2993", "protein_names_uniprotkb": "Uncharacterized protein, isoform C", "protein_names_refseq": "CG2993-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "stomach cancer (Disease Ontology:DOID:10534); Reye syndrome (Disease Ontology:DOID:14525); glaucoma (Disease Ontology:DOID:1686); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG2993)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGD9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGE4-1", "uniprot_id": [ { "id": "A0A0B4KGE4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGE4", "type": "external" } ], "mass": 69321.0, "length": 629, "protein_name": "alpha-glucosidase", "gene_name": "CD98hc", "organism": "Fruit fly", "refseq_name": "CD98 heavy chain, isoform B", "refseq_ac": [ { "id": "NP_001262355", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262355", "type": "external" } ], "gene_names_uniprotkb": "CD98hc; CG2791; Dmel\\CG2791; Dmel_CG2791; RE39378p; cd98hc", "gene_names_refseq": "CD98hc; CG2791; Dmel\\CG2791; RE39378p; cd98hc", "protein_names_uniprotkb": "alpha-glucosidase; 3.2.1.20", "protein_names_refseq": "CD98 heavy chain, isoform B; CD98hc-PB; CG2791-PB", "tax_id": 7227, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); transitional cell carcinoma (Disease Ontology:DOID:2671); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); stomach carcinoma (Disease Ontology:DOID:5517)", "pathway": " (dme:Dmel_CG2791); (R-DME-210991); (R-DME-352230); (R-DME-71240)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.20", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:1903801 L-leucine import across plasma membrane;GO:0005975 carbohydrate metabolic process;GO:0015823 phenylalanine transport;GO:1904273 L-alanine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGE4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGE5-1", "uniprot_id": [ { "id": "A0A0B4KGE5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGE5", "type": "external" } ], "mass": 130151.0, "length": 1207, "protein_name": "Bonus, isoform C", "gene_name": "bon", "organism": "Fruit fly", "refseq_name": "bonus, isoform C", "refseq_ac": [ { "id": "NP_001262765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262765", "type": "external" } ], "gene_names_uniprotkb": "bon; 06; 08; 12; 150268_at; 150269_at; 20; Bonus; Bon; CG15687; CG5206; Dmel\\CG5206; Dmel_CG5206; anon-WO0118547.418; l(3)S043420", "gene_names_refseq": "0241/08; 0249/12; 0434/20; 0487/06; 150268_at; 150269_at; Bonus; Bon; CG15687; CG5206; Dmel\\CG5206; anon-WO0118547.418; bon; l(3)S043420", "protein_names_uniprotkb": "Bonus, isoform C", "protein_names_refseq": "CG5206-PC; bon-PC; bonus, isoform C; bonus", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5206); (R-DME-9843940)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0004672 protein kinase activity;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006325 chromatin organization;GO:0009957 epidermal cell fate specification", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGE5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGF6-1", "uniprot_id": [ { "id": "A0A0B4KGF6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGF6", "type": "external" } ], "mass": 237559.0, "length": 2172, "protein_name": "HEAT repeat-containing protein 5A", "gene_name": "Heatr5", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform F", "refseq_ac": [ { "id": "NP_001262364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262364", "type": "external" } ], "gene_names_uniprotkb": "Heatr5; 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02; 16; CG5269; Dm-PITPalpha; Dmel\\CG5269; Dmel_CG5269; Gio; PITP-DM; PITP; Vib; anon-WO0142479.3; anon-WO0172774.12; anon-WO0172774.16; anon-WO0172774.28; giotto; gio; l(3)S045002c; l(3)S045002; l(3)S110416; l(3)j4A3; l(3)j5A6; l(3)j7A3; l(3)j7C8; vib-RA", "gene_names_refseq": "0450/02; 1104/16; CG5269; Dm-PITPalpha; Dmel\\CG5269; Gio; PITP-DM; PITP; Vib; anon-WO0142479.3; anon-WO0172774.12; anon-WO0172774.16; anon-WO0172774.28; giotto; gio; l(3)S045002c; l(3)S045002; l(3)S110416; l(3)j4A3; l(3)j5A6; l(3)j7A3; l(3)j7C8; vib", "protein_names_uniprotkb": "Vibrator, isoform B", "protein_names_refseq": "CG5269-PB; PITP; giotto; lethal (3) S045002c; lethal (3) S110416; lethal (3) j5A6; vib-PB; vibrator, isoform B; vibrator", "tax_id": 7227, "disease": "chylomicron retention disease (Disease Ontology:DOID:0060357)", "pathway": " (dme:Dmel_CG5269); (R-DME-1483196)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031210 phosphatidylcholine binding;GO:0035091 phosphatidylinositol binding;GO:0008526 phosphatidylinositol transfer activity;GO:0008525 phosphatidylcholine transporter activity;GO:0005548 phospholipid transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031965 nuclear membrane;GO:0032154 cleavage furrow", "go_biological_process": "GO:0007283 spermatogenesis;GO:0036090 cleavage furrow ingression;GO:0033206 meiotic cytokinesis;GO:0000916 actomyosin contractile ring contraction;GO:0000212 meiotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGG5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGH8-1", "uniprot_id": [ { "id": "A0A0B4KGH8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGH8", "type": "external" } ], "mass": 21344.0, "length": 202, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "Dmel\\CG34135", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001262385", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262385", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG34135; 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Beat-IV; CG10152; CG13823; Dmel\\CG10152; Dmel_CG10152; beat IV; beatIV", "gene_names_refseq": "Beat-IV; CG10152; CG13823; Dmel\\CG10152; beat IV; beat-IV; beatIV", "protein_names_uniprotkb": "Beaten path IV, isoform B", "protein_names_refseq": "CG10152-PB; beat-IV-PB; beaten path IV, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10152)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004895 cell adhesion receptor activity", "go_cellular_component": "GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0007416 synapse assembly;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGP4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGR8-1", "uniprot_id": [ { "id": "A0A0B4KGR8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGR8", "type": "external" } ], "mass": 7728.0, "length": 66, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44044", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262628", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44044; CG44044; Dmel_CG44044", "gene_names_refseq": "CG44044; Dmel\\CG44044", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44044-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44044)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KGR8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGS4-1", "uniprot_id": [ { "id": "A0A0B4KGS4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGS4", "type": "external" } ], "mass": 65784.0, "length": 583, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Pak3", "organism": "Fruit fly", "refseq_name": "Pak3, isoform D", "refseq_ac": [ { "id": "NP_001262638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262638", "type": "external" } ], "gene_names_uniprotkb": "Pak3; CG14895; D-Pak3; DPAK3; DPak3; DmPAK3; Dmel\\CG14895; Dmel_CG14895; Dpak3; PAK-3; PAK3; PaK3; Pak; anon-WO0118547.285; dPAK3; dpak3; pak3", "gene_names_refseq": "CG14895; D-Pak3; DPAK3; DPak3; DmPAK3; Dmel\\CG14895; Dpak3; PAK-3; PAK3; PaK3; Pak3; Pak; anon-WO0118547.285; dPAK3; dpak3; pak3", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "CG14895-PD; Pak3, isoform D; Pak3-PD; p21-activated kinase 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14895); (R-DME-2029482); (R-DME-2871796); (R-DME-389359); (R-DME-3928662); (R-DME-3928664); (R-DME-445144); (R-DME-5218920); (R-DME-5621575); (R-DME-5627123); (R-DME-5687128); (R-DME-8964616); (R-DME-9013149); (R-DME-9013406); (R-DME-9013407); (R-DME-9013420); (R-DME-9013423); (R-DME-9013424)", "pathway_count": 18, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "1.8.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.9", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001726 ruffle", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0035556 intracellular signal transduction;GO:0051965 positive regulation of synapse assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGS4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGS5-1", "uniprot_id": [ { "id": "A0A0B4KGS5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGS5", "type": "external" } ], "mass": 66737.0, "length": 586, "protein_name": "Uncharacterized protein, isoform E", "gene_name": "Dmel\\CG14693", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform E", "refseq_ac": [ { "id": "NP_001262467", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262467", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG14693; CG14693-RD; CG14693; Dmel_CG14693", "gene_names_refseq": "CG14693; Dmel\\CG14693", "protein_names_uniprotkb": "Uncharacterized protein, isoform E", "protein_names_refseq": "CG14693-PE; uncharacterized protein, isoform E", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14693)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGT9-1", "uniprot_id": [ { "id": "A0A0B4KGT9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGT9", "type": "external" } ], "mass": 53063.0, "length": 467, "protein_name": "Odorant receptor 85e", "gene_name": "Or85e", "organism": "Fruit fly", "refseq_name": "odorant receptor 85e", "refseq_ac": [ { "id": "NP_001262374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262374", "type": "external" } ], "gene_names_uniprotkb": "Or85e; 85B.1; 85e; CG9700; CR9700; DOR104; DOR85e; Dmel\\CG9700; Dmel_CG9700; Dor104; OR55; OR85e; Or104; dor104", "gene_names_refseq": "85B.1; 85e; CG9700; CR9700; DOR104; DOR85e; Dmel\\CG9700; Dor104; OR55; OR85e; Or104; Or85e; dor104", "protein_names_uniprotkb": "Odorant receptor 85e", "protein_names_refseq": "CG9700-PB; Or85e-PB; odorant receptor 104; odorant receptor 85e", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9700)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KGT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGU2-1", "uniprot_id": [ { "id": "A0A0B4KGU2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGU2", "type": "external" } ], "mass": 79037.0, "length": 735, "protein_name": "Lute, isoform D", "gene_name": "lute", "organism": "Fruit fly", "refseq_name": "lute, isoform D", "refseq_ac": [ { "id": "NP_001262663", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262663", "type": "external" } ], "gene_names_uniprotkb": "lute; CG14333; CG43226; CG5319-RA; CG5319; Dmel\\CG43226; Dmel_CG43226; anon-WO0118547.289; lute-RA", "gene_names_refseq": "CG14333; CG43226; CG5319; Dmel\\CG43226; anon-WO0118547.289; lute", "protein_names_uniprotkb": "Lute, isoform D", "protein_names_refseq": "CG43226-PD; lute, isoform D; lute-PD", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43226)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGW2-1", "uniprot_id": [ { "id": "A0A0B4KGW2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGW2", "type": "external" } ], "mass": 137601.0, "length": 1271, "protein_name": "Stripe, isoform D", "gene_name": "sr", "organism": "Fruit fly", "refseq_name": "stripe, isoform D", "refseq_ac": [ { "id": "NP_001262693", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262693", "type": "external" } ], "gene_names_uniprotkb": "sr; CG7847; Dmel\\CG7847; Dmel_CG7847; SrB; Sr; Stripe; l(3)03999; l(3)06948b; l(3)06948; sr-RC", "gene_names_refseq": "CG7847; Dmel\\CG7847; SrB; Sr; Stripe; l(3)03999; l(3)06948b; l(3)06948; sr", "protein_names_uniprotkb": "Stripe, isoform D", "protein_names_refseq": "CG7847-PD; STRIPE; StripeB; sr-PD; stripe, isoform D; striped", "tax_id": 7227, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); myelodysplastic syndrome (Disease Ontology:DOID:0050908); Charcot-Marie-Tooth disease type 4E (Disease Ontology:DOID:0110195); silicosis (Disease Ontology:DOID:10325); Alzheimer's disease (Disease Ontology:DOID:10652); pulmonary sarcoidosis (Disease Ontology:DOID:13406); breast cancer (Disease Ontology:DOID:1612); aortic valve stenosis (Disease Ontology:DOID:1712); squamous cell carcinoma (Disease Ontology:DOID:1749); arteriosclerosis (Disease Ontology:DOID:2349); asthma (Disease Ontology:DOID:2841); endometriosis (Disease Ontology:DOID:289); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); osteosarcoma (Disease Ontology:DOID:3347); middle cerebral artery infarction (Disease Ontology:DOID:3525); pulmonary fibrosis (Disease Ontology:DOID:3770); lung non-small cell carcinoma (Disease Ontology:DOID:3908); bronchiolo-alveolar adenocarcinoma (Disease Ontology:DOID:4926); pancreatitis (Disease Ontology:DOID:4989); liver cirrhosis (Disease Ontology:DOID:5082); pulmonary hypertension (Disease Ontology:DOID:6432); osteoarthritis (Disease Ontology:DOID:8398); lung disease (Disease Ontology:DOID:850); pulmonary emphysema (Disease Ontology:DOID:9675); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG7847); (R-DME-9031628)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 25, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061665 SUMO ligase activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007525 somatic muscle development;GO:0007417 central nervous system development;GO:0007517 muscle organ development;GO:0007398 ectoderm development;GO:0007390 germ-band shortening", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGW2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KGW3-1", "uniprot_id": [ { "id": "A0A0B4KGW3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KGW3", "type": "external" } ], "mass": 79419.0, "length": 716, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Glug", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001262395", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262395", "type": "external" } ], "gene_names_uniprotkb": "Glug; 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3; CG8208; Dmel\\CG8208; Dmel_CG8208; MBD2-3; MBD2; MBD3; dMBD-like", "gene_names_refseq": "CG8208; Dm Mbd2/3; DmMbd2/3; Dmel\\CG8208; MBD-like; MBD2-3; MBD2/3; MBD2; MBD3; dMBD-like; dMBD2/3; dMbD2/3", "protein_names_uniprotkb": "Methyl-CpG binding domain protein-like, isoform C", "protein_names_refseq": "CG8208-PC; MBD-like-PC; Methyl-CpG binding domain protein-like, isoform C; methyl-CpG-binding-domain-like-protein", "tax_id": 7227, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); schizophrenia (Disease Ontology:DOID:5419); rheumatoid arthritis (Disease Ontology:DOID:7148); choline deficiency disease (Disease Ontology:DOID:8456); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG8208); (R-DME-3214815); (R-DME-427413); (R-DME-6804758); (R-DME-8943724)", "pathway_count": 5, "publication_count": 12, "publication_id_list": "10471500;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016581 NuRD complex;GO:0005700 polytene chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0030261 chromosome condensation;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KGZ0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KH03-1", "uniprot_id": [ { "id": "A0A0B4KH03_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KH03", "type": "external" } ], "mass": 31819.0, "length": 284, "protein_name": "Tetraspanin", "gene_name": "Tsp96F", "organism": "Fruit fly", "refseq_name": "tetraspanin 96F, isoform B", "refseq_ac": [ { "id": "NP_001262976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262976", "type": "external" } ], "gene_names_uniprotkb": "Tsp96F; BcDNA.LD19727; BcDNA:LD19727; CG6120; Dm.Tsp96F; Dmel\\CG6120; Dmel_CG6120; LD19727; tsp96F", "gene_names_refseq": "BcDNA:LD19727; CG6120; Dm.Tsp96F; Dmel\\CG6120; LD19727; Tsp96F; tsp96F", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "CG6120-PB; Tetraspanin96F; Tsp96F-PB; tetraspanin 96F, isoform B", "tax_id": 7227, "disease": "common variable immunodeficiency 6 (Disease Ontology:DOID:0081149); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); endometrial cancer (Disease Ontology:DOID:1380); ovarian cancer (Disease Ontology:DOID:2394); prostate adenocarcinoma (Disease Ontology:DOID:2526); transitional cell carcinoma (Disease Ontology:DOID:2671); cervix carcinoma (Disease Ontology:DOID:2893); severe acute respiratory syndrome (Disease Ontology:DOID:2945); breast carcinoma (Disease Ontology:DOID:3459)", "pathway": " (dme:Dmel_CG6120); (R-DME-114608)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KH03-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KH11-1", "uniprot_id": [ { "id": "A0A0B4KH11_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KH11", "type": "external" } ], "mass": 8146.0, "length": 83, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44142", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262532", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44142; 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CG5447; Dmel_CG5447", "gene_names_refseq": "CG5447; Dmel\\CG5447", "protein_names_uniprotkb": "Ras modification protein ERF4", "protein_names_refseq": "CG5447-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5447); (R-DME-6798695); (R-DME-9648002)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane;GO:0002178 palmitoyltransferase complex", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0043001 Golgi to plasma membrane protein transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KH14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KH20-1", "uniprot_id": [ { "id": "A0A0B4KH20_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KH20", "type": "external" } ], "mass": 85245.0, "length": 775, "protein_name": "Nervous fingers 2, isoform B", "gene_name": "nerfin-2", "organism": "Fruit fly", "refseq_name": "nervous fingers 2, isoform B", "refseq_ac": [ { "id": "NP_001262446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262446", "type": "external" } ], "gene_names_uniprotkb": "nerfin-2; CG12809; Dmel\\CG12809; Dmel_CG12809; Nerfin", "gene_names_refseq": "CG12809; Dmel\\CG12809; Nerfin; nerfin-2", "protein_names_uniprotkb": "Nervous fingers 2, isoform B", "protein_names_refseq": "CG12809-PB; nerfin-2-PB; nervous fingers 2, isoform B; nervous fingers", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12809)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0030154 cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0010564 regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KH20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KH28-1", "uniprot_id": [ { "id": "A0A0B4KH28_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KH28", "type": "external" } ], "mass": 56038.0, "length": 495, "protein_name": "Syndapin, isoform C; 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Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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true }, { "uniprot_canonical_ac": "A0A0B4KH86-1", "uniprot_id": [ { "id": "A0A0B4KH86_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KH86", "type": "external" } ], "mass": 71724.0, "length": 652, "protein_name": "Inwardly rectifying potassium channel 1, isoform F; Inwardly rectifying potassium channel 1, isoform G", "gene_name": "Irk1", "organism": "Fruit fly", "refseq_name": "inwardly rectifying potassium channel 1, isoform F", "refseq_ac": [ { "id": "NP_001262861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262861", "type": "external" } ], "gene_names_uniprotkb": "Irk1; CG13836; CG44159; CG6747; DIR; Dir; Dm_3R:100326; Dm_3R:100349; Dmel\\CG44159; Dmel_CG44159; Ir-RB; Ir; Kir1; dIRK; dKirI; irk1; ir", "gene_names_refseq": "CG13836; CG44159; CG6747; DIR; Dir; Dm_3R:100326; Dm_3R:100349; Dmel\\CG44159; Irk1; Ir; Kir1; dIRK; dKirI; irk1; ir", "protein_names_uniprotkb": "Inwardly rectifying potassium channel 1, isoform F; Inwardly rectifying potassium channel 1, isoform 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(Disease Ontology:DOID:11446); prediabetes syndrome (Disease Ontology:DOID:11716); Leber congenital amaurosis (Disease Ontology:DOID:14791); alcohol use disorder (Disease Ontology:DOID:1574); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); hyperinsulinism (Disease Ontology:DOID:2018); coronary artery disease (Disease Ontology:DOID:3393); primary hyperaldosteronism (Disease Ontology:DOID:446); hypokalemia (Disease Ontology:DOID:4500); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG44159); (R-DME-1296025); (R-DME-1296041); (R-DME-1296053); (R-DME-1296067); (R-DME-382556); (R-DME-422356); (R-DME-5576886); (R-DME-5578775); (R-DME-997272)", "pathway_count": 10, "publication_count": 12, "publication_id_list": "10731132;11964404;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", 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178035.0, "length": 1597, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG14322", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001262675", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262675", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG14322; CG14322; Dmel_CG14322", "gene_names_refseq": "CG14322; Dmel\\CG14322", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG14322-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (dme:Dmel_CG14322)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005704 polytene chromosome band", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHC8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHD0-1", "uniprot_id": [ { "id": "A0A0B4KHD0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHD0", "type": "external" } ], "mass": 80023.0, "length": 740, "protein_name": "Alpha2-adrenergic-like octopamine receptor, isoform B", "gene_name": "Octalpha2R", "organism": "Fruit fly", "refseq_name": "alpha2-adrenergic-like octopamine receptor, isoform B", "refseq_ac": [ { "id": "NP_001262715", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262715", "type": "external" } ], "gene_names_uniprotkb": "Octalpha2R; CG18208; DmOctalpha2R; Dmel\\CG18208; Dmel_CG18208; Octalpha", "gene_names_refseq": "CG18208; DmOctalpha2R; Dmel\\CG18208; Octalpha2R; Octalpha", "protein_names_uniprotkb": "Alpha2-adrenergic-like octopamine receptor, isoform B", "protein_names_refseq": "CG18208-PB; Octalpha2R-PB; alpha2-adrenergic-like octopamine receptor, isoform B; octopamine receptor", "tax_id": 7227, "disease": "familial partial lipodystrophy (Disease Ontology:DOID:0050440); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); hypertension (Disease Ontology:DOID:10763); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); morphine dependence (Disease Ontology:DOID:2560); substance abuse (Disease Ontology:DOID:302); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG18208); (R-DME-390696); (R-DME-392023); (R-DME-400042); (R-DME-418594); (R-DME-418597)", "pathway_count": 6, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, 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heterotrimeric G-protein binding;GO:0008227 G protein-coupled amine receptor activity;GO:0004989 octopamine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KHD0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHF1-1", "uniprot_id": [ { "id": "A0A0B4KHF1_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHF1", "type": "external" } ], "mass": 60415.0, "length": 524, "protein_name": "Mitochondrial calcium uptake 3, isoform D", "gene_name": "MICU3", "organism": "Fruit fly", "refseq_name": "mitochondrial calcium uptake 3, isoform D", "refseq_ac": [ { "id": "NP_001262741", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262741", "type": "external" } ], "gene_names_uniprotkb": "MICU3; CG4662; Dmel\\CG4662; Dmel_CG4662; micu3", "gene_names_refseq": "CG4662; Dmel\\CG4662; MICU3; micu3", "protein_names_uniprotkb": "Mitochondrial calcium uptake 3, isoform D", "protein_names_refseq": "CG4662-PD; MICU3-PD; mitochondrial calcium uptake 3, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4662); (R-DME-8949215); (R-DME-8949664)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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intermembrane space;GO:1990246 uniplex complex", "go_biological_process": "GO:0036444 calcium import into the mitochondrion;GO:0051560 mitochondrial calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHF1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHG9-1", "uniprot_id": [ { "id": "A0A0B4KHG9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHG9", "type": "external" } ], "mass": 92010.0, "length": 819, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "Dmel\\CG13643", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001262937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262937", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13643; CG13642; CG13643; Dmel_CG13643", "gene_names_refseq": "CG13642; CG13643; Dmel\\CG13643", "protein_names_uniprotkb": "Uncharacterized protein, isoform D", "protein_names_refseq": "CG13643-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13643)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"https://www.uniprot.org/uniprot/A0A0B4KHI4", "type": "external" } ], "mass": 83012.0, "length": 761, "protein_name": "Syncrip, isoform Q", "gene_name": "Syp", "organism": "Fruit fly", "refseq_name": "syncrip, isoform Q", "refseq_ac": [ { "id": "NP_001262783", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262783", "type": "external" } ], "gene_names_uniprotkb": "Syp; AI945337; CG17838; Dmel\\CG17838; Dmel_CG17838; anon-WO0118547.613; cg17838; l(3)03806; syp", "gene_names_refseq": "AI945337; CG17838; Dmel\\CG17838; Syp; anon-WO0118547.613; cg17838; l(3)03806; syp", "protein_names_uniprotkb": "Syncrip, isoform Q", "protein_names_refseq": "CG17838-PQ; Syp-PQ; syncrip, isoform Q; syncrip", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17838); (R-DME-72163); (R-DME-72203); (R-DME-9770562)", "pathway_count": 4, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;29483512", 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"biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003730 mRNA 3'-UTR binding;GO:0048027 mRNA 5'-UTR binding;GO:0106222 lncRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0071011 precatalytic spliceosome;GO:0035770 ribonucleoprotein granule;GO:0098975 postsynapse of neuromuscular junction", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0007310 oocyte dorsal/ventral axis specification;GO:0046011 regulation of oskar mRNA translation;GO:0046843 dorsal appendage formation;GO:1900073 regulation of neuromuscular synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KHI4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHJ0-1", "uniprot_id": [ { "id": "A0A0B4KHJ0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHJ0", "type": "external" } ], "mass": 101468.0, "length": 907, "protein_name": "Grik, isoform C", "gene_name": "Grik", "organism": "Fruit fly", "refseq_name": "grik, isoform C", "refseq_ac": [ { "id": "NP_001262788", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262788", "type": "external" } ], "gene_names_uniprotkb": "Grik; CG5621; CT17756; DKaiRIC; DmelCG5621; Dmel\\CG5621; Dmel_CG5621; KaiR1C; anon-WO0138359.5", "gene_names_refseq": "CG5621; CT17756; DKaiRIC; DmelCG5621; Dmel\\CG5621; Grik; KaiR1C; anon-WO0138359.5", "protein_names_uniprotkb": "Grik, isoform C", "protein_names_refseq": "CG5621-PC; Grik-PC; grik, isoform C", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder 6 (Disease Ontology:DOID:0081182); Huntington's disease (Disease Ontology:DOID:12858); childhood absence epilepsy (Disease Ontology:DOID:1825); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (dme:Dmel_CG5621); (R-DME-451307); (R-DME-451308); (R-DME-500657)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHJ0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHJ4-1", "uniprot_id": [ { "id": "A0A0B4KHJ4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHJ4", "type": "external" } ], "mass": 515012.0, "length": 4496, "protein_name": "Dynein heavy chain at 93AB, isoform C", "gene_name": "Dhc93AB", "organism": "Fruit fly", "refseq_name": "dynein heavy chain at 93AB, isoform C", "refseq_ac": [ { "id": "NP_001262793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262793", "type": "external" } ], "gene_names_uniprotkb": "Dhc93AB; CG3723; DHC4C; DHC; Dhc 93AB; Dhc; Dmel\\CG3723; Dmel_CG3723; dhc93AB; dhc", "gene_names_refseq": "CG3723; DHC4C; DHC; Dhc 93AB; Dhc93AB; Dhc; Dmel\\CG3723; dhc93AB; dhc", 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"go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005930 axoneme;GO:0030286 dynein complex;GO:0036157 outer dynein arm;GO:0097729 9+2 motile cilium", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0007605 sensory perception of sound;GO:0003341 cilium movement;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KHJ4-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHK0-1", "uniprot_id": [ { "id": "A0A0B4KHK0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHK0", "type": "external" } ], "mass": 91746.0, "length": 807, "protein_name": "Dihydroxyacetone phosphate acyltransferase", "gene_name": "Gnpat", "organism": "Fruit fly", "refseq_name": "glyceronephosphate O-acyltransferase, isoform C", "refseq_ac": [ { "id": "NP_001262957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262957", "type": "external" } ], "gene_names_uniprotkb": "Gnpat; 8-1; CG4625; DHAP-AT; DHAPAT; Dhap-at-RA; Dhap-at; Dmel\\CG4625; Dmel_CG4625; GNPAT; GPAT; Gpat", "gene_names_refseq": "8-1; CG4625; DHAP-AT; DHAPAT; Dhap-at; Dmel\\CG4625; GNPAT; GPAT; Gnpat; Gpat", "protein_names_uniprotkb": "Dihydroxyacetone phosphate acyltransferase; 2.3.1.42; Glycerone-phosphate O-acyltransferase", "protein_names_refseq": "CG4625-PC; Gnpat-PC; dihydroxyacetone phosphate acyltansferase; dihydroxyacetone phosphate acyltransferase; glycerol 3-phosphate acyltransferase; glycerol-3-phosphate acyltransferase; glycerol-3-phosphate-acyltransferase; glyceronephosphate O-acyltransferase, isoform C", "tax_id": 7227, "disease": "rhizomelic chondrodysplasia punctata type 2 (Disease Ontology:DOID:0110852); disease of mental health (Disease Ontology:DOID:150)", "pathway": " (dme:Dmel_CG4625); (R-DME-1483166); (R-DME-75896); (R-DME-9033241)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Dihydroxyacetonephosphate acyltransferase catalyzing the first step in the biosynthesis of plasmalogens, a subset of phospholipids that differ from other glycerolipids by having an alkyl chain attached through a vinyl ether linkage at the sn-1 position of the glycerol backbone, and which unique physical properties have an impact on various aspects of cell signaling and membrane biology., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.42", "type": "external" }, { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.24.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.56", "type": "external" }, { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.5.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.26", "type": "external" }, { "id": "2.3.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.-.-", "type": "external" }, { "id": "2.3.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" }, { "id": "5.1.99.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.4", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "1.1.1.270", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.270", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" } ], "go_molecular_function": "GO:0016287 glycerone-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0008611 ether lipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHK0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHK1-1", "uniprot_id": [ { "id": "A0A0B4KHK1_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHK1", "type": "external" } ], "mass": 68620.0, "length": 597, "protein_name": "Supernumerary limbs, isoform B", "gene_name": "slmb", "organism": "Fruit fly", "refseq_name": "supernumerary limbs, isoform B", "refseq_ac": [ { "id": "NP_001262802", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262802", "type": "external" } ], "gene_names_uniprotkb": "slmb; BcDNA:GM02031; Beta-TRCP1; CG3412; Dmel\\CG3412; Dmel_CG3412; FBXW1; MENE (3R)-B; MENE(3R)-B; SLIMB; SLMB; Slimb; Slmb; beta-TRCP; beta-TrCP; betaTrCP; crd; ica; l(3)00295; shv; slimb; wel", "gene_names_refseq": "BcDNA:GM02031; CG3412; Dmel\\CG3412; FBXW1; MENE (3R)-B; MENE(3R)-B; SLIMB; SLMB; Slimb/Beta-TRCP1; Slimb/beta-TRCP; Slimb/beta-TrCP; Slimb/betaTrCP; Slimb; Slmb; beta-TrCP; betaTrCP; crd; ica; l(3)00295; shv; slimb; slmb; wel", "protein_names_uniprotkb": "Supernumerary limbs, isoform B", "protein_names_refseq": "CG3412-PB; SCF-betaTrCP complex; SLIMB; centrosome replication defective; icare; pingiel; shiva; slmb-PB; supernumerary limbs, isoform B; supernumerary limbs; wellman", "tax_id": 7227, "disease": "Menkes disease (Disease Ontology:DOID:1838)", "pathway": " (dme:Dmel_CG3412)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;10781936;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0051219 phosphoprotein binding;GO:1904713 beta-catenin destruction complex binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0007623 circadian rhythm;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4KHK1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHK8-1", "uniprot_id": [ { "id": "A0A0B4KHK8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHK8", "type": "external" } ], "mass": 55594.0, "length": 507, "protein_name": "Uncharacterized protein, isoform C; Uncharacterized protein, isoform D", "gene_name": "Dmel\\CG1607", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001263139", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263139", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG1607; CG1607; Cg1607; Dmel_CG1607; cg1607", "gene_names_refseq": "CG1607; Cg1607; Dmel\\CG1607; cg1607", "protein_names_uniprotkb": "Uncharacterized protein, isoform C; Uncharacterized protein, isoform D", "protein_names_refseq": "CG1607-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "lysinuric protein intolerance (Disease Ontology:DOID:0060439)", "pathway": " (dme:Dmel_CG1607); (R-DME-210991); (R-DME-352230); (R-DME-71240)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0015171 amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHK8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHL4-1", "uniprot_id": [ { "id": "A0A0B4KHL4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHL4", "type": "external" } ], "mass": 60127.0, "length": 537, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "gish", "organism": "Fruit fly", "refseq_name": "gilgamesh, isoform L", "refseq_ac": [ { "id": "NP_001262624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262624", "type": "external" } ], "gene_names_uniprotkb": "gish; CG6963; CK1-gamma; CK1[[gamma]]; CK1gamma; CK1; CKI-related; CKIgamma; Dmel\\CG6963; Dmel_CG6963; Gish; Hrr25; NEST:bs27c08; Spider; anon-WO0118547.425; gish-RE; ms(3)89B; spider", "gene_names_refseq": "CG6963; CK1-gamma; CK1[[gamma]]; CK1gamma; CK1; CKI-related; CKIgamma; Dmel\\CG6963; Gish; Hrr25; NEST:bs27c08; Spider; anon-WO0118547.425; gish; ms(3)89B; spider", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "CG6963-PL; CKIg-like; NEST:bs27c08; casein kinase 1gamma; gilgamesh, isoform L; gilgamesh; gish-PL; spider", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6963); (R-DME-1660661); (R-DME-209387); (R-DME-209440); (R-DME-209472)", "pathway_count": 5, "publication_count": 29, "publication_id_list": "10196136;10421629;10731132;10846164;10949033;11336703;12205098;12537568;12537572;12537573;12537574;12636921;12781135;14636582;14731402;15459103;16110336;16163385;16341016;16987508;17569856;17569867;24699734;25589440;26109356;26109357;33925313;40245499;8717036", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0070864 sperm individualization complex;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0032880 regulation of protein localization;GO:0016055 Wnt signaling pathway;GO:0008355 olfactory learning;GO:0051126 negative regulation of actin nucleation;GO:0007291 sperm individualization", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "A0A0B4KHL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHL5-1", "uniprot_id": [ { "id": "A0A0B4KHL5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHL5", "type": "external" } ], "mass": 94254.0, "length": 843, "protein_name": "Kekkon 6, isoform B", "gene_name": "kek6", "organism": "Fruit fly", "refseq_name": "kekkon 6, isoform B", "refseq_ac": [ { "id": "NP_001263151", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263151", "type": "external" } ], "gene_names_uniprotkb": "kek6; CG1804; Dmel\\CG1804; Dmel_CG1804; Kek-6; Kek6; kek-6; kek6-RA", "gene_names_refseq": "CG1804; Dmel\\CG1804; Kek-6; Kek6; kek-6; kek6", "protein_names_uniprotkb": "Kekkon 6, isoform B", "protein_names_refseq": "CG1804-PB; kek6-PB; kekkon 6, isoform B; kekkon-like", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1804)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043121 neurotrophin binding;GO:0005030 neurotrophin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0061174 type I terminal bouton", "go_biological_process": "GO:0048167 regulation of synaptic plasticity", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHM5-1", "uniprot_id": [ { "id": "A0A0B4KHM5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHM5", "type": "external" } ], "mass": 55316.0, "length": 493, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "Dmel\\CG12783", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001262644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262644", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG12783; CG12783; Dmel_CG12783", "gene_names_refseq": "CG12783; Dmel\\CG12783", "protein_names_uniprotkb": "Uncharacterized protein, isoform D", "protein_names_refseq": "CG12783-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12783)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4KHM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHR2-1", "uniprot_id": [ { "id": "A0A0B4KHR2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHR2", "type": "external" } ], "mass": 63465.0, "length": 558, "protein_name": "BRCA1-associated protein", "gene_name": "Dmel\\CG5555", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001262724", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262724", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG5555; CG5555; Dmel_CG5555", "gene_names_refseq": "CG5555; Dmel\\CG5555", "protein_names_uniprotkb": "BRCA1-associated protein; 2.3.2.27; BRAP2; Impedes mitogenic signal propagation; RING-type E3 ubiquitin transferase BRAP2", "protein_names_refseq": "CG5555-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5555); (R-DME-5673000); (R-DME-5675221)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016740 transferase activity;GO:0008139 nuclear localization sequence binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHR2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHT3-1", "uniprot_id": [ { "id": "A0A0B4KHT3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3", "type": "external" } ], "mass": 279029.0, "length": 2513, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Lrrk", "organism": "Fruit fly", "refseq_name": "Leucine-rich repeat kinase, isoform D", "refseq_ac": [ { "id": "NP_001262772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262772", "type": "external" } ], "gene_names_uniprotkb": "Lrrk; CG5483; CT17358; Dmel\\CG5483; Dmel_CG5483; LRRK2; LRRK; Lrrk2; dLRRK2; dLRRK; dLrrk2; dLrrk; lrrk", "gene_names_refseq": "CG5483; CT17358; Dmel\\CG5483; LRRK2; LRRK; Lrrk2; Lrrk; dLRRK2; dLRRK; dLrrk2; dLrrk; lrrk", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "CG5483-PD; LRRK; Leucine-rich repeat kinase, isoform D; Lrrk-PD; ortholog of LRRK2", "tax_id": 7227, "disease": "Parkinson's disease 8 (Disease Ontology:DOID:0060371); late onset Parkinson's disease (Disease Ontology:DOID:0060892); osteosclerotic metaphyseal dysplasia (Disease Ontology:DOID:0081111); osteopetrosis (Disease Ontology:DOID:13533); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dme:Dmel_CG5483)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, 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"secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0043198 dendritic shaft;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0044297 cell body", "go_biological_process": "GO:0008088 axo-dendritic transport;GO:0050808 synapse organization;GO:0050774 negative regulation of dendrite morphogenesis;GO:0006914 autophagy;GO:0051683 establishment of Golgi localization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHT3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHV1-1", "uniprot_id": [ { "id": "A0A0B4KHV1_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHV1", "type": "external" } ], "mass": 126549.0, "length": 1188, "protein_name": "Ecdysone-induced protein 93F, isoform C", "gene_name": "Eip93F", "organism": "Fruit fly", "refseq_name": "Ecdysone-induced protein 93F, isoform C", "refseq_ac": [ { "id": "NP_001262817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262817", "type": "external" } ], "gene_names_uniprotkb": "Eip93F; CG18389; Dmel\\CG18389; Dmel_CG18389; E93; Eip93f; Eip93; anon-WO02059370.58; eip93F; eip93f; l(3)93; l(3)ry93; lincRNA.833; psg11", "gene_names_refseq": "CG18389; Dmel\\CG18389; E93; Eip93F; Eip93f; Eip93; anon-WO02059370.58; eip93F; eip93f; l(3)93; l(3)ry93; lincRNA.833; psg11", "protein_names_uniprotkb": "Ecdysone-induced protein 93F, isoform C", "protein_names_refseq": "CG18389-PC; E3; Ecdysone-induced protein 93F, isoform C; Eip93F-PC; lethal (3) ry93", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18389)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHV1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHV7-1", "uniprot_id": [ { "id": "A0A0B4KHV7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHV7", "type": "external" } ], "mass": 116001.0, "length": 1080, "protein_name": "Sterile alpha motif domain-containing protein 5", "gene_name": "SKIP", "organism": "Fruit fly", "refseq_name": "shal K[+] channel interacting protein, isoform I", "refseq_ac": [ { "id": "NP_001262827", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262827", "type": "external" } ], "gene_names_uniprotkb": "SKIP; CG13863; CG13864; CG31163; CG5736; CG7086; CG7087; Dmel\\CG31163; Dmel_CG31163", "gene_names_refseq": "CG13863; CG13864; CG31163; CG5736; CG7086; CG7087; Dmel\\CG31163; SKIP", "protein_names_uniprotkb": "Sterile alpha motif domain-containing protein 5", "protein_names_refseq": "CG31163-PI; SKIP-PI; shal K[+] channel interacting protein, isoform I; shal K[+] channel interacting protein; skal K[+] channel interacting protein", "tax_id": 7227, "disease": "dyschromatosis universalis hereditaria (Disease Ontology:DOID:0060304); immunodeficiency 102 (Disease Ontology:DOID:0061072)", "pathway": " (dme:Dmel_CG31163)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" }, { "id": "5.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.-", "type": "external" }, { "id": "2.4.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.18", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" }, { "id": "4.1.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.4", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "5.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.5", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "2.4.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.11", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0008466 glycogenin glucosyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0005978 glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LFW5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LFW7-1", "uniprot_id": [ { "id": "A0A0B4LFW7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LFW7", "type": "external" } ], "mass": 7395.0, "length": 62, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44624", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001286625", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286625", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44624; CG44624; Dmel_CG44624", "gene_names_refseq": "CG44624; Dmel\\CG44624", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44624-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44624)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4LFW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LFY6-1", "uniprot_id": [ { "id": "A0A0B4LFY6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LFY6", "type": "external" } ], "mass": 43048.0, "length": 375, "protein_name": "Uncharacterized protein, isoform G", "gene_name": "CG15672; Dmel\\CG30222", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform G", "refseq_ac": [ { "id": "NP_001286681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286681", "type": "external" } ], "gene_names_uniprotkb": "CG15672; Dmel\\CG30222; CG12709; CG15672; CG30222; Dmel\\CG30222; Dmel_CG30222", "gene_names_refseq": "CG12709; CG15672; CG30222; Dmel\\CG30222", "protein_names_uniprotkb": "Uncharacterized protein, isoform G", "protein_names_refseq": "CG30222-PG; uncharacterized protein, isoform G", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30222)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4LFY6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LFY7-1", "uniprot_id": [ { "id": "A0A0B4LFY7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LFY7", "type": "external" } ], "mass": 15719.0, "length": 138, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44622", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001286622", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286622", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44622; CG44622; Dmel_CG44622; lincRNA.354", "gene_names_refseq": "CG44622; Dmel\\CG44622; lincRNA.354", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44622-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44622)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4LFY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LFY9-1", "uniprot_id": [ { "id": "STING_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LFY9", "type": "external" } ], "mass": 40183.0, "length": 343, "protein_name": "Stimulator of interferon genes protein homolog", "gene_name": "Sting", "organism": "Fruit fly", "refseq_name": "sting, isoform B", "refseq_ac": [ { "id": "NP_001286256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286256", "type": "external" } ], "gene_names_uniprotkb": "Sting; CG1667", "gene_names_refseq": "CG1667; Dmel\\CG1667; STING; Sting; dSTING; dSting; dmSTING", "protein_names_uniprotkb": "Stimulator of interferon genes protein homolog; dSTING; dmSTING", "protein_names_refseq": "CG1667-PB; STING; Sting-PB; sting, isoform B", "tax_id": 7227, "disease": "STING-associated vasculopathy with onset in infancy (Disease Ontology:DOID:0111457); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526)", "pathway": " (dme:Dmel_CG1667); (R-DME-1834941); (R-DME-3134975); (R-DME-3249367); (R-DME-6798695)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "10731132;12537572;29924997;29934091;30119996;33262294;34261127;34261128", "class_list": "", "function": "Facilitator of innate immune signaling that binds cyclic dinucleotides produced in response to infection by bacteria and/or viruses, and promotes the activation of the NF-kappa-B transcription factor Rel (Relish) (PubMed:29924997, PubMed:29934091, PubMed:30119996, PubMed:33262294, PubMed:34261127, PubMed:34261128). Recognizes and binds cyclic di-GMP (c-di-GMP), a cyclic dinucleotide messenger produced by bacteria such as L.monocytogenes, leading to activation of the peptidoglycan recognition protein (IMD) signaling pathway and activation of Rel (Relish) (PubMed:29924997). Innate immune response is triggered in response to double-stranded RNA from viruses delivered to the cytoplasm: Sting acts by specifically binding cyclic dinucleotides 3',2'-cGAMP and 2',3'-cGAMP produced by cGlr1 and cGlr2 in response to RNA virus in the cytosol (PubMed:34261127, PubMed:34261128). Has a strong preference for 3',2'-cGAMP compared to other cyclic dinucleotides such as 2',3'-cGAMP or 3'3'-c-di-GMP (PubMed:34261127). Upon binding to 3',2'-cGAMP, activates an antiviral immune response, leading to the activation of Rel (Relish) (PubMed:34261127, PubMed:34261128). Activated in brain in response to Zika virus infection, leading to autophagy (PubMed:29934091)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWJ4", "ec_number_list": [], "go_molecular_function": "GO:0035438 cyclic-di-GMP binding;GO:0061507 2',3'-cyclic GMP-AMP binding;GO:0140704 3',2'-cyclic GMP-AMP binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005776 autophagosome", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0016239 positive regulation of macroautophagy;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4LFY9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LG03-1", "uniprot_id": [ { "id": "A0A0B4LG03_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LG03", "type": "external" } ], "mass": 21484.0, "length": 185, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG33136; NEST:bs04e10", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001286583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286583", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG33136; NEST:bs04e10; CG33136; Dmel\\CG33136; Dmel_CG33136; NEST:bs04e10", "gene_names_refseq": "CG33136; Dmel\\CG33136; NEST:bs04e10", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG33136-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33136)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LG03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LG18-1", "uniprot_id": [ { "id": "A0A0B4LG18_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LG18", "type": "external" } ], "mass": 83339.0, "length": 740, "protein_name": "Uncharacterized protein, isoform B", "gene_name": "Dmel\\CG9313", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001286657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286657", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG9313; CG9313; Dmel_CG9313", "gene_names_refseq": "CG9313; Dmel\\CG9313", "protein_names_uniprotkb": "Uncharacterized protein, isoform B", "protein_names_refseq": "CG9313-PB; dynein; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); primary ciliary dyskinesia 1 (Disease Ontology:DOID:0110594)", "pathway": " (dme:Dmel_CG9313)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0036157 outer dynein arm", "go_biological_process": "GO:0007605 sensory perception of sound;GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LG18-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LG22-1", "uniprot_id": [ { "id": "A0A0B4LG22_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LG22", "type": "external" } ], "mass": 2628.0, "length": 23, "protein_name": "Uncharacterized protein, isoform A; 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CG3860; Dmel_CG3860", "gene_names_refseq": "CG3860; Dmel\\CG3860", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "CG3860-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); autosomal dominant nonsyndromic deafness 67 (Disease Ontology:DOID:0110588); status epilepticus (Disease Ontology:DOID:1824)", "pathway": " (dme:Dmel_CG3860); (R-DME-192105)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032934 sterol binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LGH8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LGJ9-1", "uniprot_id": [ { "id": "A0A0B4LGJ9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LGJ9", "type": "external" } ], "mass": 60627.0, "length": 537, "protein_name": "2.3.1.15; 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Uncharacterized protein, isoform B", "gene_name": "CG3419", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_001286841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286841", "type": "external" } ], "gene_names_uniprotkb": "CG3419; CG45069; Dmel\\CG45069; Dmel_CG45069", "gene_names_refseq": "CG3419; CG45069; Dmel\\CG45069", "protein_names_uniprotkb": "Uncharacterized protein, isoform A; Uncharacterized protein, isoform B", "protein_names_refseq": "CG45069-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45069)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LGM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LGM5-1", "uniprot_id": [ { "id": "A0A0B4LGM5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LGM5", "type": "external" } ], "mass": 116564.0, "length": 1047, "protein_name": "6.3.4.-; 6.3.4.15; Holocarboxylase synthetase, isoform C", "gene_name": "Hcs", "organism": "Fruit fly", "refseq_name": "holocarboxylase synthetase, isoform C", "refseq_ac": [ { "id": "NP_001287175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287175", "type": "external" } ], "gene_names_uniprotkb": "Hcs; CG14670; Dmel\\CG14670; Dmel_CG14670; HCS; HSC; NEST:bs27h05", "gene_names_refseq": "CG14670; Dmel\\CG14670; HCS; HSC; Hcs; NEST:bs27h05", "protein_names_uniprotkb": "6.3.4.-; 6.3.4.15; Holocarboxylase synthetase, isoform C", "protein_names_refseq": "CG14670-PC; Hcs-PC; holocarboxylase synthetase, isoform C; holocarboxylase synthetase", "tax_id": 7227, "disease": "holocarboxylase synthetase deficiency (Disease Ontology:DOID:859)", "pathway": " (dme:Dmel_CG14670); (R-DME-196780)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.-", "type": "external" }, { "id": "6.3.4.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.15", "type": "external" }, { "id": "6.4.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.2", "type": "external" }, { "id": "6.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.1", "type": "external" }, { "id": "6.4.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.4", "type": "external" } ], "go_molecular_function": "GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LGM5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LGN7-1", "uniprot_id": [ { "id": "A0A0B4LGN7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LGN7", "type": "external" } ], "mass": 52633.0, "length": 488, "protein_name": "Defective proboscis extension response 16, isoform C", "gene_name": "dpr16", "organism": "Fruit fly", "refseq_name": "defective proboscis extension response 16, isoform C", "refseq_ac": [ { "id": "NP_001287169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287169", "type": "external" } ], "gene_names_uniprotkb": "dpr16; 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CG10180; CG4370; Dmel\\CG4370; Dmel_CG4370; Kir2; dIRK-2; dKirII; dKir; irk2", "gene_names_refseq": "CG10180; CG4370; Dmel\\CG4370; Irk2; Kir2; dIRK-2; dKirII; dKir; irk2", "protein_names_uniprotkb": "Inwardly rectifying potassium channel 2, isoform D", "protein_names_refseq": "CG4370-PD; Irk2-PD; inwardly rectifying potassium channel 2, isoform D", "tax_id": 7227, "disease": "Andersen-Tawil syndrome (Disease Ontology:DOID:0050434); familial atrial fibrillation (Disease Ontology:DOID:0050650); metabolic acidosis (Disease Ontology:DOID:0050758); short QT syndrome (Disease Ontology:DOID:0050793); atrial fibrillation (Disease Ontology:DOID:0060224); EAST syndrome (Disease Ontology:DOID:0060484); familial periodic paralysis (Disease Ontology:DOID:1029); hypokalemia (Disease Ontology:DOID:4500); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG4370); (R-DME-1296025); (R-DME-1296041); (R-DME-1296053); (R-DME-1296067); (R-DME-382556); (R-DME-422356); (R-DME-5576886); (R-DME-5578775); (R-DME-997272)", "pathway_count": 10, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 9, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0006813 potassium ion transport;GO:0034765 regulation of monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane;GO:0035220 wing disc development", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "A0A0B4LHI9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LHJ2-1", "uniprot_id": [ { "id": "A0A0B4LHJ2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LHJ2", "type": "external" } ], "mass": 9839.0, "length": 89, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG45079", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001287371", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287371", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG45079; 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Uncharacterized protein, isoform E", "gene_name": "CG6982", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001287471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287471", "type": "external" } ], "gene_names_uniprotkb": "CG6982; CG17618; CG45049; CG6982-RC; Dmel\\CG45049; Dmel_CG45049", "gene_names_refseq": "CG17618; CG45049; CG6982; Dmel\\CG45049", "protein_names_uniprotkb": "Uncharacterized protein, isoform D; Uncharacterized protein, isoform E", "protein_names_refseq": "CG45049-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "erythrokeratodermia variabilis (Disease Ontology:DOID:0050467); mutilating palmoplantar keratoderma with periorificial keratotic plaques (Disease Ontology:DOID:0112011)", "pathway": " (dme:Dmel_CG45049); (R-DME-6809371)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0016020 membrane;GO:0005918 septate junction", "go_biological_process": "GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LHK8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LHM2-1", "uniprot_id": [ { "id": "A0A0B4LHM2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LHM2", "type": "external" } ], "mass": 38617.0, "length": 346, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG45095", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001287519", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287519", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG45095; CG45095; Dmel_CG45095; FBgn0266534", "gene_names_refseq": "CG45095; Dmel\\CG45095; FBgn0266534", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG45095-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45095)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4LHM2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LHM3-1", "uniprot_id": [ { "id": "A0A0B4LHM3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LHM3", "type": "external" } ], "mass": 79021.0, "length": 707, "protein_name": "carboxylesterase", "gene_name": "Est17", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001287487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287487", "type": "external" } ], "gene_names_uniprotkb": "Est17; 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:GABA-B-R2; BcDNA.GH07312; BcDNA:GH07312; CG6706; D-GABA-B-R2; D-GABA[[B]]R2; D-Gaba2; Dmel\\CG6706; Dmel_CG6706; GABA B R2; GABA-BR2; GABA-[[B]]R2; GABA2; GABAB(R2); GABAB-R2; GABABR-R2; GABABR2; GABA[[B]]-R2; GABA[[B]]R2; GB2; GBR; GH07312; anon-WO0170980.58; anon-WO0170980.59; dGB2", "gene_names_refseq": ":GABA-B-R2; BcDNA:GH07312; CG6706; D-GABA-B-R2; D-GABA[[B]]R2; D-Gaba2; Dmel\\CG6706; GABA B R2; GABA-B-R2; GABA-BR2; GABA-[[B]]R2; GABA2; GABAB(R2); GABAB-R2; GABABR-R2; GABABR2; GABA[[B]]-R2; GABA[[B]]R2; GB2; GBR; GH07312; anon-WO0170980.58; anon-WO0170980.59; dGB2", "protein_names_uniprotkb": "Gamma-aminobutyric acid type B receptor subunit 2; G-protein coupled receptor 51", "protein_names_refseq": "CG6706-PC; GABA-B-R2-PC; GABA[[B]]- 2 receptor; GABA[[B]]receptor2; metabotropic GABA-B receptor subtype 2, isoform C; metabotropic GABA-B receptor subtype 2; metabotropic GABA[[B]] receptor 2", "tax_id": 7227, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); developmental and epileptic encephalopathy 59 (Disease Ontology:DOID:0080291); 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CG44954; Dmel_CG44954; lincRNA.900", "gene_names_refseq": "CG44954; Dmel\\CG44954; lincRNA.900", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44954-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44954)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4LHX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LHY0-1", "uniprot_id": [ { "id": "A0A0B4LHY0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LHY0", "type": "external" } ], "mass": 21032.0, "length": 186, "protein_name": "Yellow-emperor, isoform D", "gene_name": "ymp", "organism": "Fruit fly", "refseq_name": "yellow-emperor, isoform D", "refseq_ac": [ { "id": "NP_001287531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287531", "type": "external" } ], "gene_names_uniprotkb": "ymp; 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CG 17367; CG17367; CG5908; Dmel\\CG17367; Dmel_CG17367; LNK; SH2B; dSH2B; lnk", "gene_names_refseq": "CG 17367; CG17367; CG5908; Dmel\\CG17367; LNK; Lnk; SH2B; dSH2B; lnk", "protein_names_uniprotkb": "Lnk, isoform D", "protein_names_refseq": "CG17367-PD; Lnk, isoform D; Lnk-PD", "tax_id": 7227, "disease": "chromosome 16p11.2 deletion syndrome, 220-kb (Disease Ontology:DOID:0060398); familial erythrocytosis 1 (Disease Ontology:DOID:0060652); colorectal carcinoma (Disease Ontology:DOID:0080199); essential thrombocythemia (Disease Ontology:DOID:2224); myelofibrosis (Disease Ontology:DOID:4971); chronic myeloid leukemia (Disease Ontology:DOID:8552); colorectal cancer (Disease Ontology:DOID:9256); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG17367); (R-DME-983231)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity;GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0060180 female mating behavior;GO:0007165 signal transduction;GO:0040008 regulation of growth;GO:1904263 positive regulation of TORC1 signaling;GO:0033500 carbohydrate homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LHY5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LI00-1", "uniprot_id": [ { "id": "A0A0B4LI00_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LI00", "type": "external" } ], "mass": 7749.0, "length": 69, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44290", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001287561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287561", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44290; 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Once in the nucleus, integrase performs the integration of the dsDNA into the host genome., [UniProtKB]; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends., [UniProtKB]; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.26.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.4", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003964 RNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006310 DNA recombination;GO:0006508 proteolysis;GO:0032196 transposition;GO:0015074 DNA integration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0B7P3V8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000010.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B7P7M6-1", "uniprot_id": [ { "id": "A0A0B7P7M6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B7P7M6", "type": "external" } ], "mass": 104907.0, "length": 890, "protein_name": "Lethal (2) 41Ab, isoform A", "gene_name": "l(2)41Ab", "organism": "Fruit fly", "refseq_name": "lethal (2) 41Ab, isoform A", "refseq_ac": [ { "id": "NP_001104357", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104357", "type": "external" } ], "gene_names_uniprotkb": "l(2)41Ab; 1(2R)B; 41Ab; CG40214; CG40334; CG41265; Dmel\\CG41265; Dmel_CG41265; GroupI; l(2)EMS45-10; l(2R)B", "gene_names_refseq": "1(2R)B; 41Ab; CG40214; CG40334; CG41265; Dmel\\CG41265; GroupI; l(2)41Ab; l(2)EMS45-10; l(2R)B", "protein_names_uniprotkb": "Lethal (2) 41Ab, isoform A", "protein_names_refseq": "CG41265-PA; l(2)41Ab-PA; lethal (2) 41Ab, isoform A", "tax_id": 7227, "disease": "primary ciliary dyskinesia 15 (Disease Ontology:DOID:0110623); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG41265)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005930 axoneme", "go_biological_process": "GO:0003341 cilium movement;GO:0070286 axonemal dynein complex assembly;GO:0035082 axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B7P7M6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B7P9G0-1", "uniprot_id": [ { "id": "UEX_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "type": "external" } ], "mass": 93283.0, "length": 834, "protein_name": "Unextended protein", "gene_name": "uex", "organism": "Fruit fly", "refseq_name": "unextended, isoform F", "refseq_ac": [ { "id": "NP_001104390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390", "type": "external" } ], "gene_names_uniprotkb": "uex; 41Ad; CG42595; GroupIII; l(2)41Ad", "gene_names_refseq": "41Ad; CG40084; CG42595; CR41594; Dmel\\CG42595; EMS45-73; GroupIII; IR3; l(2)41Ad; l(2)EMS34-7; l(2)IR3; l(2R)A'; l(2R)EMS45-73; l(2Rh)IR3; uex", "protein_names_uniprotkb": "Unextended protein; Putative metal transporter uex", "protein_names_refseq": "CG42595-PF; lethal (2) IR3; uex-PF; unextended, isoform F", "tax_id": 7227, "disease": "renal hypomagnesemia 6 (Disease Ontology:DOID:0060884); Jalili syndrome (Disease Ontology:DOID:0111404); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG42595)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;31404830", "class_list": "", "function": "Probable metal transporter (By similarity). Acts downstream of PRL-1 and protects the nervous system against olfactory carbon dioxide stimulation (PubMed:31404830)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:1903830 magnesium ion transmembrane transport;GO:0007616 long-term memory;GO:0010960 magnesium ion homeostasis;GO:0006873 intracellular monoatomic ion homeostasis;GO:0140115 export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0B7P9G0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DGP1-1", "uniprot_id": [ { "id": "SGSN1_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DGP1", "type": "external" } ], "mass": 7727.0, "length": 68, "protein_name": "Small integral membrane protein 10-like protein 3", "gene_name": "SMIM10L3", "organism": "Human", "refseq_name": "salivary gland specific protein SAGSIN1", "refseq_ac": [ { "id": "NP_001382924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382924", "type": "external" } ], "gene_names_uniprotkb": "SMIM10L3; SAGSIN1", "gene_names_refseq": "C7orf70; SAGSIN1; SMIM10L3", "protein_names_uniprotkb": "Small integral membrane protein 10-like protein 3; Salivary gland-specific protein SAGSIN1", "protein_names_refseq": "salivary gland specific protein 1; salivary gland specific protein SAGSIN1", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "30429286;31844290;32265295", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0C4DGP1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH24-1", "uniprot_id": [ { "id": "KV621_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH24", "type": "external" } ], "mass": 12430.0, "length": 114, "protein_name": "Immunoglobulin kappa variable 6-21", "gene_name": "IGKV6-21", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV6-21", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin kappa variable 6-21", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "11549845;17576170;20176268;22158414;24600447", "class_list": "", "function": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, 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"https://www.uniprot.org/uniprot/A0A0C4DH25", "type": "external" } ], "mass": 12515.0, "length": 116, "protein_name": "Immunoglobulin kappa variable 3D-20", "gene_name": "IGKV3D-20", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV3D-20", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin kappa variable 3D-20", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": " (R-HSA-166663); (R-HSA-173623); (R-HSA-198933); (R-HSA-202733); (R-HSA-2029481); (R-HSA-2029482); (R-HSA-2029485); (R-HSA-2168880); (R-HSA-2454202); (R-HSA-2730905); (R-HSA-2871796); (R-HSA-2871809); (R-HSA-2871837); (R-HSA-5690714); (R-HSA-9664323); (R-HSA-9664422); (R-HSA-9679191); (R-HSA-977606); (R-HSA-983695)", "pathway_count": 19, "publication_count": 532, "publication_id_list": 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The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 53.3, "record_id": "A0A0C4DH25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH26-1", "uniprot_id": [ { "id": "KVD41_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH26", "type": "external" } ], "mass": 12570.0, "length": 115, "protein_name": "Probable non-functional immunoglobulin kappa variable 6D-41", "gene_name": "IGKV6D-41", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV6D-41", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional immunoglobulin kappa variable 6D-41", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 3, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0C4DH26-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH27-1", "uniprot_id": [ { "id": "TRGV8_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH27", "type": "external" } ], "mass": 13335.0, "length": 118, "protein_name": "T cell receptor gamma variable 8", "gene_name": "TRGV8", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGV8; TCRGV8", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor gamma variable 8", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "23348415;24387714;24600447;25674089;28920588;32938616", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0C4DH27-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH28-1", "uniprot_id": [ { "id": "TRGV4_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH28", "type": "external" } ], "mass": 13152.0, "length": 118, "protein_name": "T cell receptor gamma variable 4", "gene_name": "TRGV4", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGV4; TCRGV4", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor gamma variable 4", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "23348415;24387714;24600447;25674089;28920588", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447). 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This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 8, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0C4DH28-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH29-1", "uniprot_id": [ { "id": "HV103_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH29", "type": "external" } ], "mass": 13008.0, "length": 117, "protein_name": "Immunoglobulin heavy variable 1-3", "gene_name": "IGHV1-3", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV1-3", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy variable 1-3", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "11340299;17576170;20176268;22158414;24600447", "class_list": "", "function": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0C4DH29-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH30-1", "uniprot_id": [ { "id": "HV316_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH30", "type": "external" } ], "mass": 13070.0, "length": 117, "protein_name": "Probable non-functional immunoglobulin heavy variable 3-16", "gene_name": "IGHV3-16", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV3-16", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional immunoglobulin heavy variable 3-16", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;27999743;35580925;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin heavy chains (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 9, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0C4DH30-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH31-1", "uniprot_id": [ { "id": "HV118_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH31", "type": "external" } ], "mass": 12820.0, "length": 117, "protein_name": "Immunoglobulin heavy variable 1-18", "gene_name": "IGHV1-18", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV1-18", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy variable 1-18", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;32350084;32502341", "class_list": "", "function": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0C4DH31-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH32-1", "uniprot_id": [ { "id": "HV320_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH32", "type": "external" } ], "mass": 12673.0, "length": 117, "protein_name": "Immunoglobulin heavy variable 3-20", "gene_name": "IGHV3-20", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV3-20", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy variable 3-20", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;29557506;38253038;8490662", "class_list": "", "function": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. 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Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. 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Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. 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Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. 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Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 53.1, "record_id": "A0A0C4DH73-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH90-1", "uniprot_id": [ { "id": "A0A0C4DH90_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C4DH90", "type": "external" } ], "mass": 12586.0, "length": 116, "protein_name": "Immunoglobulin kappa variable 3/OR2-268 (non-functional)", "gene_name": "IGKV3OR2-268", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV3OR2-268", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin kappa variable 3/OR2-268 (non-functional)", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11237011", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0C4DH90-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DH96-1", "uniprot_id": [ { "id": "A0A0C4DH96_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DH96", "type": "external" } ], "mass": 126147.0, "length": 1174, "protein_name": "Sidestep V, isoform B", "gene_name": "side-V", "organism": "Fruit fly", "refseq_name": "sidestep V, isoform B", "refseq_ac": [ { "id": "NP_611765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611765", "type": "external" } ], "gene_names_uniprotkb": "side-V; 34371; CG13546; CG13547; CG13548; CG30188; CG34371-RA; CG34371; CT32921; CT32922; Dmel\\CG34371; Dmel_CG34371", "gene_names_refseq": "34371; CG13546; CG13547; CG13548; CG30188; CG34371; CT32921; CT32922; Dmel\\CG34371; side-V", "protein_names_uniprotkb": "Sidestep V, isoform B", "protein_names_refseq": "CG34371-PB; side-V-PB; sidestep V, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34371)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0C4DH96-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHA5-1", "uniprot_id": [ { "id": "A0A0C4DHA5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHA5", "type": "external" } ], "mass": 49581.0, "length": 443, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "Dmel\\CG1116; Rgp1", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_730894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730894", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG1116; Rgp1; CG1116-RB; CG1116; Dmel\\CG1116; Dmel_CG1116; Rgp1; anon-WO0118547.337; cg1116", "gene_names_refseq": "CG1116; Dmel\\CG1116; Rgp1; anon-WO0118547.337; cg1116", "protein_names_uniprotkb": "Uncharacterized protein, isoform D", "protein_names_refseq": "CG1116-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1116); (R-DME-6811440); (R-DME-8876198)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0034066 Ric1-Rgp1 guanyl-nucleotide exchange factor complex;GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0C4DHA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHC8-1", "uniprot_id": [ { "id": "A0A0C4DHC8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHC8", "type": "external" } ], "mass": 63039.0, "length": 564, "protein_name": "Aldehyde dehydrogenase type III, isoform Q", "gene_name": "Aldh-III", "organism": "Fruit fly", "refseq_name": "aldehyde dehydrogenase type III, isoform Q", "refseq_ac": [ { "id": "NP_724562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724562", "type": "external" } ], "gene_names_uniprotkb": "Aldh-III; ALDH-III; ALDH; Aldh-III-RE; Aldh-III-RO; AldhIII; CG11140; CT41571; Dhap; Dmel\\CG11140; Dmel_CG11140; FALDH; l(2)03610", "gene_names_refseq": "ALDH-III; ALDH; Aldh-III; AldhIII; CG11140; CT41571; Dhap; Dmel\\CG11140; FALDH; l(2)03610", "protein_names_uniprotkb": "Aldehyde dehydrogenase type III, isoform Q", "protein_names_refseq": "Aldh-III-PQ; CG11140-PQ; aldehyde dehydrogenase type III, isoform Q; fatty aldehyde dehydrogenase", "tax_id": 7227, "disease": "Sjogren-Larsson syndrome (Disease Ontology:DOID:14501); arteriosclerosis (Disease Ontology:DOID:2349)", "pathway": " (dme:Dmel_CG11140); (R-DME-211945); (R-DME-389599); (R-DME-6798695); (R-DME-9603798); (R-DME-9609523); (R-DME-9845614)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0004029 aldehyde dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0016020 membrane;GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006081 aldehyde metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0C4DHC8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHD7-1", "uniprot_id": [ { "id": "A0A0C4DHD7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHD7", "type": "external" } ], "mass": 91469.0, "length": 810, "protein_name": "Alpha-catenin related, isoform C", "gene_name": "alpha-Catr", "organism": "Fruit fly", "refseq_name": "alpha-catenin related, isoform C", "refseq_ac": [ { "id": "NP_726389", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726389", "type": "external" } ], "gene_names_uniprotkb": "alpha-Catr; CG2987; Dmel\\CG2987; Dmel_CG2987; alpha-catenin-Related; alpha-catenin-related", "gene_names_refseq": "CG2987; Dmel\\CG2987; alpha-Catr; alpha-catenin-Related; alpha-catenin-related", "protein_names_uniprotkb": "Alpha-catenin related, isoform C", "protein_names_refseq": "CG2987-PC; alpha-Catr-PC; alpha-catenin related, isoform C; alpha-catenin-related", "tax_id": 7227, "disease": "Duchenne muscular dystrophy (Disease Ontology:DOID:11723)", "pathway": " (dme:Dmel_CG2987)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071944 cell periphery", "go_biological_process": "GO:0007155 cell adhesion;GO:0007266 Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0C4DHD7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHF5-1", "uniprot_id": [ { "id": "A0A0C4DHF5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHF5", "type": "external" } ], "mass": 62371.0, "length": 556, "protein_name": "Mind the gap, isoform E", "gene_name": "mtg", "organism": "Fruit fly", "refseq_name": "mind the gap, isoform E", "refseq_ac": [ { "id": "NP_731221", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_731221", "type": "external" } ], "gene_names_uniprotkb": "mtg; 10; CG7549; Dmel\\CG7549; Dmel_CG7549; MTG; Mtg; l(3)S084910b; l(3)S084910; mtg-RG; mtg-RH", "gene_names_refseq": "0849/10; CG7549; Dmel\\CG7549; MTG; Mtg; l(3)S084910b; l(3)S084910; mtg", "protein_names_uniprotkb": "Mind the gap, isoform E", "protein_names_refseq": "CG7549-PE; Mind-the-Gap; lethal (3) S084910b; mind the gap, isoform E; mind the gap; mtg-PE", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7549)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008061 chitin binding;GO:0097367 carbohydrate derivative binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0043195 terminal bouton;GO:0043083 synaptic cleft", "go_biological_process": "GO:0007416 synapse assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0C4DHF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHF6-1", "uniprot_id": [ { "id": "A0A0C4DHF6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHF6", "type": "external" } ], "mass": 137703.0, "length": 1262, "protein_name": "Dystroglycan 1", "gene_name": "Dg", "organism": "Fruit fly", "refseq_name": "dystroglycan, isoform D", "refseq_ac": [ { "id": "NP_788363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788363", "type": "external" } ], "gene_names_uniprotkb": "Dg; CG18250; CT41273; DG; DmDG; Dmel\\CG18250; Dmel_CG18250; alpha-DG; atu; dgn; dg; dys", "gene_names_refseq": "CG18250; CT41273; DG; Dg; DmDG; Dmel\\CG18250; alpha-DG; atu; dgn; dg; dys", "protein_names_uniprotkb": "Dystroglycan 1; Dystroglycan; Dystrophin-associated glycoprotein 1", "protein_names_refseq": "CG18250-PD; Dg-PD; alphaDystroglycan; atsugari; dystroglican; dystroglycan, isoform D; dystroglycan-like; dystroglycan", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); Fukuyama congenital muscular dystrophy (Disease Ontology:DOID:0050559); muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); autosomal recessive limb-girdle muscular dystrophy type 2D (Disease Ontology:DOID:0110278); autosomal recessive limb-girdle muscular dystrophy type 2P (Disease Ontology:DOID:0110293); congenital muscular dystrophy-dystroglycanopathy type A9 (Disease Ontology:DOID:0111232); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); primary biliary cholangitis (Disease Ontology:DOID:12236); dilated cardiomyopathy (Disease Ontology:DOID:12930); inclusion body myositis (Disease Ontology:DOID:3429); myocardial infarction (Disease Ontology:DOID:5844); muscular atrophy (Disease Ontology:DOID:767); type 2 diabetes mellitus (Disease Ontology:DOID:9352); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (dme:Dmel_CG18250); (R-DME-3000178); (R-DME-8932504); (R-DME-8932505); (R-DME-8932506); (R-DME-9010553); (R-DME-9913351); (R-DME-9939291)", "pathway_count": 8, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0043236 laminin binding;GO:0008307 structural constituent of muscle;GO:0005055 laminin receptor activity", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0046716 muscle cell cellular homeostasis;GO:0030036 actin cytoskeleton organization;GO:0045214 sarcomere organization;GO:0048854 brain morphogenesis;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0C4DHF6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHF7-1", "uniprot_id": [ { "id": "A0A0C4DHF7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHF7", "type": "external" } ], "mass": 101130.0, "length": 899, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44434", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_788406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788406", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44434; CG15086; CG44434; Dmel_CG44434", "gene_names_refseq": "CG15086; CG44434; Dmel\\CG44434", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44434-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44434)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0C4DHF7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000100000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4DHF9-1", "uniprot_id": [ { "id": "A0A0C4DHF9_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4DHF9", "type": "external" } ], "mass": 31655.0, "length": 290, "protein_name": "Entomoglyceroporin 2, isoform C", "gene_name": "Eglp2", "organism": "Fruit fly", "refseq_name": "entomoglyceroporin 2, isoform C", "refseq_ac": [ { "id": "NP_788433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788433", "type": "external" } ], "gene_names_uniprotkb": "Eglp2; 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primary biliary cholangitis (Disease Ontology:DOID:12236); malaria (Disease Ontology:DOID:12365); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); uveitis (Disease Ontology:DOID:13141); blindness (Disease Ontology:DOID:1432); retinal vein occlusion (Disease Ontology:DOID:1727); status epilepticus (Disease Ontology:DOID:1824); diabetic ketoacidosis (Disease Ontology:DOID:1837); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); thymoma (Disease Ontology:DOID:3275); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); temporal lobe epilepsy (Disease Ontology:DOID:3328); middle cerebral artery infarction (Disease Ontology:DOID:3525); brain edema (Disease Ontology:DOID:4724); retinal disease (Disease Ontology:DOID:5679); central pontine myelinolysis (Disease Ontology:DOID:636); cataract (Disease Ontology:DOID:83); neuromyelitis optica (Disease Ontology:DOID:8869); diabetic retinopathy (Disease Ontology:DOID:8947); cerebral amyloid angiopathy (Disease Ontology:DOID:9246); 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CG42596; Dmel\\CG42596; Dmel_CG42596; Dpr21", "gene_names_refseq": "CG42596; Dmel\\CG42596; Dpr21; dpr21", "protein_names_uniprotkb": "Defective proboscis extension response 21", "protein_names_refseq": "CG42596-PC; defective proboscis extension response 21; dpr21-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42596)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0032589 neuron projection membrane", "go_biological_process": "GO:0050808 synapse organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0C4DHN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4FEI3-1", "uniprot_id": [ { "id": "A0A0C4FEI3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0C4FEI3", "type": "external" } ], "mass": 113020.0, "length": 1029, "protein_name": "Uncharacterized protein, isoform F", "gene_name": "Dmel\\CG6184", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform F", "refseq_ac": [ { "id": "NP_732443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_732443", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG6184; 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Granny smith, isoform F", "gene_name": "grsm", "organism": "Fruit fly", "refseq_name": "granny smith, isoform F", "refseq_ac": [ { "id": "NP_731749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_731749", "type": "external" } ], "gene_names_uniprotkb": "grsm; BcDNA:LD41548; CG7340; Dmel\\CG7340; Dmel_CG7340; granny-smith-RB; granny-smith; l(3)c00064", "gene_names_refseq": "BcDNA:LD41548; CG7340; Dmel\\CG7340; granny-smith; grsm; l(3)c00064", "protein_names_uniprotkb": "3.4.-.-; Granny smith, isoform F", "protein_names_refseq": "CG7340-PF; Leucyl-aminopeptidase; aminopeptidase; granny smith, isoform F; granny-smith; grsm-PF; lethal (3) c00064", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7340)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0070006 metalloaminopeptidase activity;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0C4FEI8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C4JZ93-1", "uniprot_id": [ { "id": "A0A0C4JZ93_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0C4JZ93", "type": "external" } ], "mass": 11094.0, "length": 105, "protein_name": "Neuropeptide FF-amide peptide", "gene_name": "NPFF", "organism": "Chicken", "refseq_name": "pro-FMRFamide-related neuropeptide FF", "refseq_ac": [ { "id": "XP_015155812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155812", "type": "external" } ], "gene_names_uniprotkb": "NPFF", "gene_names_refseq": "NPFF", "protein_names_uniprotkb": "Neuropeptide FF-amide peptide", "protein_names_refseq": "pro-FMRFamide-related neuropeptide FF", "tax_id": 9031, "disease": "", "pathway": " (gga:107055409)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0C4JZ93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C5B5G6-1", "uniprot_id": [ { "id": "MOTSC_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0C5B5G6", "type": "external" } ], "mass": 2175.0, "length": 16, "protein_name": "Mitochondrial-derived peptide MOTS-c", "gene_name": "MT-RNR1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MT-RNR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial-derived peptide MOTS-c; Mitochondrial open reading frame of the 12S rRNA-c", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 16, "publication_id_list": "25738459;26289118;29096170;29886458;29983246;30468456;30725119;31081069;31369811;31694019;31931370;32182209;33468709;33473109;33554779;7219534", "class_list": "", "function": "Regulates insulin sensitivity and metabolic homeostasis (PubMed:25738459, PubMed:33468709). Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK) (PubMed:25738459). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity (PubMed:25738459). In response to metabolic stress, translocates to the nucleus where it binds to antioxidant response elements (ARE) present in the promoter regions of a number of genes and plays a role in regulating nuclear gene expression in an NFE2L2-dependent manner and increasing cellular resistance to metabolic stress (PubMed:29983246). Increases mitochondrial respiration and levels of CPT1A and cytokines IL1B, IL6, IL8, IL10 and TNF in senescent cells (PubMed:29886458). Increases activity of the serine/threonine protein kinase complex mTORC2 and reduces activity of the PTEN phosphatase, thus promoting phosphorylation of AKT (PubMed:33554779). This promotes AKT-mediated phosphorylation of transcription factor FOXO1 which reduces FOXO1 activity, leading to reduced levels of MSTN and promotion of skeletal muscle growth (PubMed:33554779). Promotes osteogenic differentiation of bone marrow mesenchymal stem cells via the TGFB/SMAD pathway (PubMed:30468456). Promotes osteoblast proliferation and osteoblast synthesis of type I collagens COL1A1 and COL1A2 via the TGFB/SMAD pathway (PubMed:31081069)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0033687 osteoblast proliferation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048630 skeletal muscle tissue growth;GO:0032147 activation of protein kinase activity;GO:0071902 positive regulation of protein serine/threonine kinase activity", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "A0A0C5B5G6-1", "record_type": "protein", "filter_code": "0000000.0100100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0C6E596-1", "uniprot_id": [ { "id": "A0A0C6E596_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0C6E596", "type": "external" } ], "mass": 28418.0, "length": 274, "protein_name": "Atoh1 protein; Atonal bHLH transcription factor 1", "gene_name": "Atoh1", "organism": "Chicken", "refseq_name": "protein atonal homolog 1", "refseq_ac": [ { "id": "XP_004941187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941187", "type": "external" } ], "gene_names_uniprotkb": "Atoh1; ATOH1", "gene_names_refseq": "ATOH1", "protein_names_uniprotkb": "Atoh1 protein; Atonal bHLH transcription factor 1", "protein_names_refseq": "protein atonal homolog 1", "tax_id": 9031, "disease": "", "pathway": " (gga:101750213)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25412697", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_004941187.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0014014 negative regulation of gliogenesis;GO:1904036 negative regulation of epithelial cell apoptotic process;GO:0007219 Notch signaling pathway;GO:0042472 inner ear morphogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0C6E596-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0D5BWD2-1", "uniprot_id": [ { "id": "A0A0D5BWD2_PIG", "url": "https://www.uniprot.org/uniprot/A0A0D5BWD2", "type": "external" } ], "mass": 31015.0, "length": 281, "protein_name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "gene_name": "C1QBP", "organism": "Pig", "refseq_name": "complement component 1 Q subcomponent-binding protein, mitochondrial", "refseq_ac": [ { "id": "XP_020923404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923404", "type": "external" } ], "gene_names_uniprotkb": "C1QBP", "gene_names_refseq": "C1QBP", "protein_names_uniprotkb": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "protein_names_refseq": "complement component 1 Q subcomponent-binding protein, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-140837); (R-SSC-8980692); (R-SSC-9013106)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0001849 complement component C1q complex binding;GO:0005540 hyaluronic acid binding;GO:0030984 kininogen binding;GO:0060703 deoxyribonuclease inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006397 mRNA processing;GO:0043065 positive regulation of apoptotic process;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0D5BWD2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0D5W690-1", "uniprot_id": [ { "id": "A0A0D5W690_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0D5W690", "type": "external" } ], "mass": 107075.0, "length": 937, "protein_name": "RNA helicase", "gene_name": "rigi", "organism": "Zebrafish", "refseq_name": "antiviral innate immune response receptor RIG-I", "refseq_ac": [ { "id": "NP_001293024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001293024", "type": "external" } ], "gene_names_uniprotkb": "rigi; RIG-Ia; RIG-Ib; RIG-Ic; RIG-Id; RIG-I; ddx58", "gene_names_refseq": "RIG-Ia; RIG-Ib; RIG-Ic; RIG-Id; RIG-I; ddx58; rigi", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; RIG-1; antiviral innate immune response receptor RIG-I; probable ATP-dependent RNA helicase DDX58; retinoic acid-inducible protein Ia; retinoic acid-inducible protein Ib; retinoic acid-inducible protein Ic; retinoic acid-inducible protein Id; rig1", "tax_id": 7955, "disease": "Fanconi anemia (Disease Ontology:DOID:13636)", "pathway": " (dre:100333797)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "15520368;19474100;20045026;23594743;25100833;25265425;35589132;35764162;35982787;36405758;36577070", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KM281808.1 [ECO:0000332] RNAseq introns :: partial sample support SAMN01765705 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KM281808.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Results suggested the functional conservation of RIG-I receptors in the NF-kappaB and IFN signaling pathways between teleosts and mammals, providing a perspective into the evolutionary history of RIG-I-mediated antiviral innate immunity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0051607 defense response to virus;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0006355 regulation of DNA-templated transcription;GO:0060337 type I interferon-mediated signaling pathway;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0D5W690-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0D9SEG7-1", "uniprot_id": [ { "id": "A0A0D9SEG7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0D9SEG7", "type": "external" } ], "mass": 44726.0, "length": 413, "protein_name": "Homeobox A3", "gene_name": "HOXA3", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HOXA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeobox A3", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0071837 HMG box domain binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0030878 thyroid gland development;GO:2000648 positive regulation of stem cell proliferation;GO:0060017 parathyroid gland development;GO:0021615 glossopharyngeal nerve morphogenesis;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0D9SEG7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0D9SF12-1", "uniprot_id": [ { "id": "CC163_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0D9SF12", "type": "external" } ], "mass": 16203.0, "length": 145, "protein_name": "Transmembrane protein CCDC163", "gene_name": "CCDC163", "organism": "Human", "refseq_name": "transmembrane protein CCDC163 isoform 1", "refseq_ac": [ { "id": "NP_001096071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096071", "type": "external" } ], "gene_names_uniprotkb": "CCDC163; C1orf231; CCDC163P; hCG_1780060", "gene_names_refseq": "C1orf231; CCDC163P; CCDC163", "protein_names_uniprotkb": "Transmembrane protein CCDC163; Coiled-coil domain-containing protein 163; coiled-coil domain containing 163 pseudogene", "protein_names_refseq": "coiled-coil domain containing 163, pseudogene; coiled-coil domain-containing protein 163; transmembrane protein CCDC163 isoform 1; transmembrane protein CCDC163", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "11237011;23481700;25576301;28832583;33592498", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 3, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0D9SF12-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0E3D804-1", "uniprot_id": [ { "id": "A0A0E3D804_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0E3D804", "type": "external" } ], "mass": 113199.0, "length": 997, "protein_name": "RNA helicase", "gene_name": "ifih1", "organism": "Zebrafish", "refseq_name": "interferon-induced helicase C domain-containing protein 1", "refseq_ac": [ { "id": "NP_001295492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295492", "type": "external" } ], "gene_names_uniprotkb": "ifih1; MDA5a; MDA5b; si:dkey-81j5.2", "gene_names_refseq": "MDA5a; MDA5b; ifih1; si:dkey-81j5.2", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "interferon-induced helicase C domain-containing protein 1; mda5; melanoma differentiation-associated protein 5a; melanoma differentiation-associated protein 5b", "tax_id": 7955, "disease": "Aicardi-Goutieres syndrome (Disease Ontology:DOID:0050629); immunodeficiency 95 (Disease Ontology:DOID:0061065); Fanconi anemia (Disease Ontology:DOID:13636); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dre:565759); (R-DRE-5689880)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "19474100;20728541;23594743;24116956;24683187;25100833;25445907;35764162;35982787;36314827;36577070;38077314", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: JX462556.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476756, SAMEA4476806 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JX462556.1. On May 13, 2015 this sequence version replaced XP_694124.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; A zebrafish model of Ifih1-driven Aicardi-Goutieres syndrome reproduces the interferon signature and the exacerbated inflammation of patients. Erratum:[Front Immunol. 2025 Jan 06;15:1544703. doi: 10.3389/fimmu.2024.1544703. PMID: 39835125] Publication Status: Online-Only, [RefSeq, PubMed]; Shorter spliced form, MDA5b when co-transfected with MDA5a or mitochondrial antiviral signalling protein (MAVS), induced a significantly higher level of interferon promoter activity, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.26.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.26.1", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0039530 MDA-5 signaling pathway;GO:0140374 antiviral innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0E3D804-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0E3KLW5-1", "uniprot_id": [ { "id": "A0A0E3KLW5_PIG", "url": "https://www.uniprot.org/uniprot/A0A0E3KLW5", "type": "external" } ], "mass": 19451.0, "length": 172, "protein_name": "diphosphoinositol-polyphosphate diphosphatase", "gene_name": "NUDT3", "organism": "Pig", "refseq_name": "diphosphoinositol polyphosphate phosphohydrolase 1", "refseq_ac": [ { "id": "NP_001295339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295339", "type": "external" } ], "gene_names_uniprotkb": "NUDT3", "gene_names_refseq": "NUDT3; nudix", "protein_names_uniprotkb": "diphosphoinositol-polyphosphate diphosphatase; 3.6.1.52", "protein_names_refseq": "diphosphoinositol polyphosphate phosphohydrolase 1; nucleoside diphosphate linked moiety X-type motif 3; nudix-type motif 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100737442); (R-SSC-1855167)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000298 endopolyphosphatase activity;GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity;GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity;GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071543 diphosphoinositol polyphosphate metabolic process;GO:0071544 diphosphoinositol polyphosphate catabolic process;GO:1901907 diadenosine pentaphosphate catabolic process;GO:1901909 diadenosine hexaphosphate catabolic process;GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0E3KLW5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0E4G213-1", "uniprot_id": [ { "id": "A0A0E4G213_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0E4G213", "type": "external" } ], "mass": 60174.0, "length": 546, "protein_name": "ETT ergothioneine transporter; Uncharacterized protein LOC799908", "gene_name": "slc22a21", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC799908", "refseq_ac": [ { "id": "NP_001295487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295487", "type": "external" } ], "gene_names_uniprotkb": "slc22a21; SLC22A4; si:ch1073-409b12.4", "gene_names_refseq": "SLC22A4; si:ch1073-409b12.4; slc22a21", "protein_names_uniprotkb": "ETT ergothioneine transporter; Uncharacterized protein LOC799908", "protein_names_refseq": "C2; ETT ergothioneine transporter; ETTzf; solute carrier family 22 (organic cation transporter), member 21; uncharacterized protein LOC799908", "tax_id": 7955, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); myelodysplastic syndrome (Disease Ontology:DOID:0050908); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); systemic primary carnitine deficiency disease (Disease Ontology:DOID:14365); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); congestive heart failure (Disease Ontology:DOID:6000); inherited metabolic disorder (Disease Ontology:DOID:655); rheumatoid arthritis (Disease Ontology:DOID:7148); Crohn's disease (Disease Ontology:DOID:8778)", "pathway": " (dre:799908); (R-DRE-200425); (R-DRE-549127)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "23594743;25746775;26469318;35295584", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: HG917106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from HG917106.1. On May 12, 2015 this sequence version replaced XP_009294018.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015651 quaternary ammonium group transmembrane transporter activity;GO:0015199 amino-acid betaine transmembrane transporter activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0015697 quaternary ammonium group transport;GO:0006811 monoatomic ion transport;GO:0015838 amino-acid betaine transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0E4G213-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0F6YFH3-1", "uniprot_id": [ { "id": "A0A0F6YFH3_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0F6YFH3", "type": "external" } ], "mass": 24934.0, "length": 224, "protein_name": "Peroxiredoxin-like 2A", "gene_name": "PRXL2A", "organism": "Chicken", "refseq_name": "selenoprotein U", "refseq_ac": [ { "id": "NP_001180448", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180448", "type": "external" } ], "gene_names_uniprotkb": "PRXL2A", "gene_names_refseq": "C10ORF58; C6H10orf58; FAM213A; PAMM; PRXL2A; SELENOU", "protein_names_uniprotkb": "Peroxiredoxin-like 2A; Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; Redox-regulatory protein FAM213A", "protein_names_refseq": "Protein PAMM; UPF0765 protein C10orf58 homolog; family with sequence similarity 213 member A; peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes; peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; redox-regulatory protein FAM213A; redox-regulatory protein PAMM; selenoprotein U", "tax_id": 9031, "disease": "", "pathway": " (gga:423625)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ720950.1, HAEK01129750.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JAENSK010000227.1. The protein encoded by this gene belongs to a subfamily of FAM213A/selenoprotein U (SelU), within a peroxiredoxin-like FAM213 superfamily. SelU is unusual in that it has restricted phylogenetic distribution in vertebrates, such as in chicken and fish. Other vertebrate members of this family, including mammals, contain cysteine-containing homologues. SelU proteins contain UxxC (U for selenocysteine and C for cysteine) motif in place of the catalytic CxxC motif found in cysteine-containing homologues. The latter function as redox regulatory proteins, suggesting a similar role for SelU proteins. Like majority of selenoproteins, SelU contains a single selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]. Transcript Variant: This variant (2) contains an alternate 5' non-coding exon derived from a downstream promoter, compared to variant 1. Variants 1 and 2 encode the same selenoprotein., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016209 antioxidant activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0F6YFH3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0F7C9F3-1", "uniprot_id": [ { "id": "A0A0F7C9F3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0F7C9F3", "type": "external" } ], "mass": 188531.0, "length": 1655, "protein_name": "IQGAP1 protein; Ras GTPase-activating-like protein IQGAP1", "gene_name": "iqgap1", "organism": "Zebrafish", "refseq_name": "ras GTPase-activating-like protein IQGAP1", "refseq_ac": [ { "id": "NP_001295895", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295895", "type": "external" } ], "gene_names_uniprotkb": "iqgap1; IQGAP1; im:7152854; im:7156663", "gene_names_refseq": "im:7152854; im:7156663; iqgap1", "protein_names_uniprotkb": "IQGAP1 protein; Ras GTPase-activating-like protein IQGAP1", "protein_names_refseq": "ras GTPase-activating-like protein IQGAP1", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-373753); (R-DRE-5626467); (R-DRE-5674135); (R-DRE-6798695); (R-DRE-8980692); (R-DRE-9013106); (R-DRE-9013148); (R-DRE-9013149); (R-DRE-9013404); (R-DRE-9013406); (R-DRE-9013420); (R-DRE-9013424)", "pathway_count": 12, "publication_count": 7, "publication_id_list": "16466575;19619483;23594743;25504979;26286209;26469318;27935819", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KP862587.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KP862587.1. On May 19, 2015 this sequence version replaced XP_009301707.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005516 calmodulin binding;GO:0051015 actin filament binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0031252 cell leading edge", "go_biological_process": "GO:0007173 epidermal growth factor receptor signaling pathway;GO:0010761 fibroblast migration;GO:1903479 mitotic actomyosin contractile ring assembly actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0F7C9F3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0F7EVQ6-1", "uniprot_id": [ { "id": "A0A0F7EVQ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0F7EVQ6", "type": "external" } ], "mass": 188078.0, "length": 1639, "protein_name": "IQGAP3 protein; Ras GTPase-activating-like protein IQGAP3", "gene_name": "iqgap3", "organism": "Zebrafish", "refseq_name": "ras GTPase-activating-like protein IQGAP3", "refseq_ac": [ { "id": "NP_001295896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295896", "type": "external" } ], "gene_names_uniprotkb": "iqgap3; IQGAP3", "gene_names_refseq": "iqgap3", "protein_names_uniprotkb": "IQGAP3 protein; Ras GTPase-activating-like protein IQGAP3", "protein_names_refseq": "ras GTPase-activating-like protein IQGAP3", "tax_id": 7955, "disease": "nonsyndromic deafness (Disease Ontology:DOID:0050563)", "pathway": " (dre:100537977); (R-DRE-5626467); (R-DRE-8980692); (R-DRE-9013026); (R-DRE-9013106); (R-DRE-9013148); (R-DRE-9013149); (R-DRE-9013406)", "pathway_count": 8, "publication_count": 3, "publication_id_list": "23594743;26286209;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KP862589.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. 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The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JS06-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JSK1-1", "uniprot_id": [ { "id": "A0A0G2JSK1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JSK1", "type": "external" } ], "mass": 46477.0, "length": 416, "protein_name": "Serine (or cysteine) proteinase inhibitor, clade A, member 3C", "gene_name": "Serpina3c", "organism": "Rat", "refseq_name": "serine protease inhibitor A3K precursor", "refseq_ac": [ { "id": "NP_036789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036789", "type": "external" } ], "gene_names_uniprotkb": "Serpina3c", "gene_names_refseq": "CPi-21; GHR-P63; Kbp; Klkbp; SPI-2.3; SPI-2; SPI2; Serpina3c; Serpina3k; Spin2b; Spin2", "protein_names_uniprotkb": "Serine (or cysteine) proteinase inhibitor, clade A, member 3C", "protein_names_refseq": "contrapsin-like protease inhibitor 1; growth hormone-regulated proteinase inhibitor; kallikrein-binding protein; kallistatin; serine (or cysteine) peptidase inhibitor, clade A, member 3K; serine protease inhibitor 2b; serine protease inhibitor A3K precursor; serine protease inhibitor A3K; serpin A3K; thyroid hormone-regulated protein", "tax_id": 10116, "disease": "developmental and epileptic encephalopathy 31B (Disease Ontology:DOID:0070376); developmental and epileptic encephalopathy 31A (Disease Ontology:DOID:0080437); Alzheimer's disease (Disease Ontology:DOID:10652); adult respiratory distress syndrome (Disease Ontology:DOID:11394); Creutzfeldt-Jakob disease (Disease Ontology:DOID:11949); cystic fibrosis (Disease Ontology:DOID:1485); generalized epilepsy (Disease Ontology:DOID:1827); severe acute respiratory syndrome (Disease Ontology:DOID:2945); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); lung adenocarcinoma (Disease Ontology:DOID:3910); collagen disease (Disease Ontology:DOID:854); vasculitis (Disease Ontology:DOID:865)", "pathway": " (rno:24794)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "20299474;20351274;21693707;23129128;35147994", "class_list": "", "function": "KBP suppressed lipopolysaccharide-induced TNF-alpha production via upregulating SOCS3 expression., [RefSeq, PubMed]; Pivotal role for alpha1-antichymotrypsin in skin repair, [RefSeq, PubMed]; SERPINA3K is a high-affinity, endogenous antagonist of LRP6, [RefSeq, PubMed]; SERPINA3K is an antifibrogenic factor, and its antifibrogenic activity is through blocking the Wnt pathway. Decreased SERPINA3K levels may contribute to the fibrosis in diabetic retinopathy., [RefSeq, PubMed]; Transient response of serpinA3 during cellular stress., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0001937 negative regulation of endothelial cell proliferation;GO:0034097 response to cytokine;GO:0016525 negative regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JSK1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JSN6-1", "uniprot_id": [ { "id": "A0A0G2JSN6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JSN6", "type": "external" } ], "mass": 60855.0, "length": 547, "protein_name": "Adhesion G protein-coupled receptor G3", "gene_name": "Adgrg3", "organism": "Rat", "refseq_name": "probable G-protein coupled receptor 97 precursor", "refseq_ac": [ { "id": "NP_001417145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417145", "type": "external" } ], "gene_names_uniprotkb": "Adgrg3", "gene_names_refseq": "Adgrg3; Gpr97", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor G3; G-protein coupled receptor 97", "protein_names_refseq": "G protein-coupled receptor 97; probable G-protein coupled receptor 97 precursor; probable G-protein coupled receptor 97", "tax_id": 10116, "disease": "", "pathway": " (rno:291854); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0030183 B cell differentiation;GO:0030334 regulation of cell migration;GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JSN6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JSU2-1", "uniprot_id": [ { "id": "A0A0G2JSU2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JSU2", "type": "external" } ], "mass": 144179.0, "length": 1307, "protein_name": "Adhesion G protein-coupled receptor A3", "gene_name": "Adgra3", "organism": "Rat", "refseq_name": "probable G-protein coupled receptor 125 precursor", "refseq_ac": [ { "id": "NP_001419740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419740", "type": "external" } ], "gene_names_uniprotkb": "Adgra3", "gene_names_refseq": "Adgra3; Gpr125", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor A3; G-protein coupled receptor 125", "protein_names_refseq": "G protein-coupled receptor 125; probable G-protein coupled receptor 125 precursor; probable G-protein coupled receptor 125", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Orphan receptor that may have a role in planar cell polarity pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JSU2-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JSV3-1", "uniprot_id": [ { "id": "A0A0G2JSV3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JSV3", "type": "external" } ], "mass": 34806.0, "length": 318, "protein_name": "Ribose-phosphate pyrophosphokinase 1", "gene_name": "Prps1l3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Prps1l3", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribose-phosphate pyrophosphokinase 1; 2.7.6.1; Phosphoribosyl pyrophosphate synthase I", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-73843)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.6.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.6.1", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JSV3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JT03-1", "uniprot_id": [ { "id": "A0A0G2JT03_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JT03", "type": "external" } ], "mass": 8128.0, "length": 70, "protein_name": "BBSome interacting protein 1", "gene_name": "Bbip1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bbip1", "gene_names_refseq": "", "protein_names_uniprotkb": "BBSome interacting protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Bardet-Biedl syndrome 18 (Disease Ontology:DOID:0110140)", "pathway": " (R-RNO-5620922)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0060170 ciliary membrane;GO:0034464 BBSome", "go_biological_process": "GO:0002260 lymphocyte homeostasis;GO:0042755 eating behavior;GO:0060271 cilium assembly;GO:0016055 Wnt signaling pathway;GO:0034101 erythrocyte homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JT03-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JT20-1", "uniprot_id": [ { "id": "A0A0G2JT20_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JT20", "type": "external" } ], "mass": 61564.0, "length": 560, "protein_name": "MIER family member 2", "gene_name": "ENSRNOG00000070264; Mier2", "organism": "Rat", "refseq_name": "mesoderm induction early response protein 2 isoform X1", "refseq_ac": [ { "id": "XP_017450403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017450403", "type": "external" } ], "gene_names_uniprotkb": "ENSRNOG00000070264; Mier2; Mier2", "gene_names_refseq": "Mier2; RGD1307278", "protein_names_uniprotkb": "MIER family member 2", "protein_names_refseq": "mesoderm induction early response protein 2 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional repressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0004407 histone deacetylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JT20-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JT23-1", "uniprot_id": [ { "id": "A0A0G2JT23_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JT23", "type": "external" } ], "mass": 57378.0, "length": 499, "protein_name": "Nuclear receptor-binding protein 2", 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In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JT97-1", "uniprot_id": [ { "id": "A0A0G2JT97_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JT97", "type": "external" } ], "mass": 64491.0, "length": 561, "protein_name": "Lactase-like protein", "gene_name": "Lctl", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lctl", "gene_names_refseq": "", "protein_names_uniprotkb": "Lactase-like protein; Klotho/lactase-phlorizin hydrolase-related protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "kidney disease (Disease Ontology:DOID:557)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005903 brush border;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0007601 visual perception;GO:0002089 lens morphogenesis in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JT97-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTA4-1", "uniprot_id": [ { "id": "A0A0G2JTA4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTA4", "type": "external" } ], "mass": 281854.0, "length": 2440, "protein_name": "GTPase, very large interferon inducible 1", "gene_name": "Gvin1", "organism": "Rat", "refseq_name": "GTPase, very large interferon inducible 1", "refseq_ac": [ { "id": "NP_001395702", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395702", "type": "external" } ], "gene_names_uniprotkb": "Gvin1; LOC499229", "gene_names_refseq": "Gvin1", "protein_names_uniprotkb": "GTPase, very large interferon inducible 1", "protein_names_refseq": "GTPase, very large interferon inducible 1; interferon-induced very large GTPase 1-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JTA4-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTB0-1", "uniprot_id": [ { "id": "A0A0G2JTB0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTB0", "type": "external" } ], "mass": 128059.0, "length": 1179, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Tnks2", "organism": "Rat", "refseq_name": "poly [ADP-ribose] polymerase tankyrase-2", "refseq_ac": [ { "id": "NP_001101077", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101077", "type": "external" } ], "gene_names_uniprotkb": "Tnks2", "gene_names_refseq": "Tnks2", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "poly [ADP-ribose] polymerase tankyrase-2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:309512); (R-RNO-201681); (R-RNO-4641257); (R-RNO-5689880); (R-RNO-8948751)", "pathway_count": 5, 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"external" } ], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0070213 protein auto-ADP-ribosylation;GO:0040014 regulation of multicellular organism growth;GO:0035264 multicellular organism growth;GO:0070198 protein localization to chromosome, telomeric region;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTB0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTB2-1", "uniprot_id": [ { "id": "A0A0G2JTB2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTB2", "type": "external" } ], "mass": 83307.0, "length": 727, "protein_name": "1,4-alpha-glucan branching enzyme", "gene_name": "Gbe1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gbe1", "gene_names_refseq": "", "protein_names_uniprotkb": "1,4-alpha-glucan branching enzyme; 2.4.1.18", "protein_names_refseq": "", "tax_id": 10116, "disease": "porphyria (Disease Ontology:DOID:13268); glycogen storage disease IV (Disease Ontology:DOID:2750); pulmonary tuberculosis (Disease Ontology:DOID:2957)", "pathway": " (R-RNO-3322077)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 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structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (By similarity). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon", "go_biological_process": "GO:1905522 negative regulation of macrophage migration;GO:0016477 cell migration;GO:0032496 response to lipopolysaccharide;GO:0035556 intracellular signal transduction;GO:0042472 inner ear morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JTR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000001001.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTT6-1", "uniprot_id": [ { "id": "A0A0G2JTT6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTT6", "type": "external" } ], "mass": 533361.0, "length": 4869, "protein_name": "HECT-type E3 ubiquitin transferase", "gene_name": "Herc1", "organism": "Rat", "refseq_name": "probable E3 ubiquitin-protein ligase HERC1", "refseq_ac": [ { "id": "NP_001407845", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001407845", "type": "external" } ], "gene_names_uniprotkb": "Herc1", "gene_names_refseq": "Herc1", "protein_names_uniprotkb": "HECT-type E3 ubiquitin transferase; 2.3.2.26", "protein_names_refseq": "hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1; probable E3 ubiquitin-protein ligase HERC1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-983168)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0031175 neuron projection development;GO:0050885 neuromuscular process controlling balance;GO:0007420 brain development;GO:0006914 autophagy;GO:0010507 negative regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JTT6-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTT7-1", "uniprot_id": [ { "id": "A0A0G2JTT7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTT7", "type": "external" } ], "mass": 78755.0, "length": 716, "protein_name": "Rho GTPase activating protein 22", "gene_name": "Arhgap22", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 22 isoform 2", "refseq_ac": [ { "id": "NP_001423653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423653", "type": "external" } ], "gene_names_uniprotkb": "Arhgap22", "gene_names_refseq": "Arhgap22", "protein_names_uniprotkb": "Rho GTPase activating protein 22", "protein_names_refseq": "rho GTPase-activating protein 22 isoform 2; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Plays a negative role in TGF-beta response regulation and a positive role in cell migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" } ], "go_molecular_function": "GO:0042799 histone H4K20 methyltransferase activity;GO:0140944 histone H4K20 monomethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005700 polytene chromosome", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTW4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTX2-1", "uniprot_id": [ { "id": "A0A0G2JTX2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTX2", "type": "external" } ], "mass": 19434.0, "length": 178, "protein_name": "PRA1 family protein", "gene_name": "Praf2", "organism": "Rat", "refseq_name": "PRA1 family protein 2", "refseq_ac": [ { "id": "NP_001102483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102483", "type": "external" } ], "gene_names_uniprotkb": "Praf2", "gene_names_refseq": "Praf2; RGD1566287", "protein_names_uniprotkb": "PRA1 family protein", "protein_names_refseq": "PRA1 domain family 2; PRA1 family protein 2", "tax_id": 10116, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (rno:367743)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0016020 membrane;GO:0098794 postsynapse;GO:0098793 presynapse", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JTX2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTX7-1", "uniprot_id": [ { "id": "A0A0G2JTX7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTX7", "type": "external" } ], "mass": 289291.0, "length": 2635, "protein_name": "Collagen alpha-5(VI) chain", "gene_name": "Col6a5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Col6a5", "gene_names_refseq": "", "protein_names_uniprotkb": "Collagen alpha-5(VI) chain; Collagen alpha-1(XXIX) chain", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1650814)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Collagen VI acts as a cell-binding protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0005581 collagen trimer", "go_biological_process": "GO:0007155 cell adhesion;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTX7-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTY1-1", "uniprot_id": [ { "id": "A0A0G2JTY1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", "type": "external" } ], "mass": 70174.0, "length": 618, "protein_name": "Grainyhead-like transcription factor 1", "gene_name": "Grhl1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Grhl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Grainyhead-like transcription factor 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061436 establishment of skin barrier;GO:0006355 regulation of DNA-templated transcription;GO:0008544 epidermis development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTY1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTY4-1", "uniprot_id": [ { "id": "NFAC3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTY4", "type": "external" } ], "mass": 115656.0, "length": 1076, "protein_name": "Nuclear factor of activated T-cells, cytoplasmic 3", "gene_name": "Nfatc3", "organism": "Rat", "refseq_name": "nuclear factor of activated T-cells, cytoplasmic 3 isoform 2", "refseq_ac": [ { "id": "NP_001421511", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421511", "type": "external" } ], "gene_names_uniprotkb": "Nfatc3; Nfat4", "gene_names_refseq": "NFAT4; NFATx; Nfatc3", "protein_names_uniprotkb": "Nuclear factor of activated T-cells, cytoplasmic 3; NFATc3; NFATx; T-cell transcription factor NFAT4", "protein_names_refseq": "T cell transcription factor NFAT4; nuclear factor of activated T-cells, cytoplasmic 3 isoform 2; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3", "tax_id": 10116, "disease": "", "pathway": " (rno:361400); (R-RNO-2025928); (R-RNO-2871809); (R-RNO-5607763)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "19538478;22673903;30980393;33495839;34845564;36373478;36825443;38242872", "class_list": "", "function": "Acts as a regulator of transcriptional activation. Binds to the TNFSF11/RANKL promoter region and promotes TNFSF11 transcription (By similarity). Binding to the TNFSF11 promoter region is increased by high levels of Ca(2+) which induce NFATC3 expression and may lead to regulation of TNFSF11 expression in osteoblasts (By similarity). Plays a role in promoting mesenteric arterial wall remodeling in response to the intermittent hypoxia-induced increase in EDN1 and ROCK signaling (By similarity). As a result NFATC3 colocalizes with F-actin filaments, translocates to the nucleus and promotes transcription of the smooth muscle hypertrophy and differentiation marker ACTA2 (By similarity). Promotes lipopolysaccharide-induced apoptosis and hypertrophy in cardiomyocytes (PubMed:30980393). Following JAK/STAT signaling activation and as part of a complex with NFATC4 and STAT3, binds to the alpha-beta E4 promoter region of CRYAB and activates transcription in cardiomyocytes (PubMed:19538478). In conjunction with NFATC4, involved in embryonic heart development via maintenance of cardiomyocyte survival, proliferation and differentiation (By similarity). Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 (By similarity). Required for thymocyte maturation during DN3 to DN4 transition and during positive selection (By similarity). Positively regulates macrophage-derived polymicrobial clearance, via binding to the promoter region and promoting transcription of NOS2 resulting in subsequent generation of nitric oxide (By similarity). Involved in Ca(2+)-mediated transcriptional responses upon Ca(2+) influx via ORAI1 CRAC channels., [UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed]; Induction of cardiomyocyte calcification is dependent on FoxO1/NFATc3/Runx2 signaling., [RefSeq, PubMed]; MiR-339-3p promotes AT1-AA-induced vascular inflammation by upregulating NFATc3 protein expression in vascular smooth muscle cells., [RefSeq, PubMed]; MicroRNA153 attenuates hypoxiainduced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3. Erratum:[Mol Med Rep. 2022 Nov;26(5):332. doi: 10.3892/mmr.2022.12848. PMID: 36082819], [RefSeq, PubMed]; MicroRNA153 induces apoptosis by targeting NFATc3 to improve vascular remodeling in pulmonary hypertension., [RefSeq, PubMed]; The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005667 transcription regulator complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0014904 myotube cell development;GO:0035886 vascular associated smooth muscle cell differentiation;GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation;GO:0007507 heart development;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0G2JTY4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001001.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTZ0-1", "uniprot_id": [ { "id": "A0A0G2JTZ0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTZ0", "type": "external" } ], "mass": 21050.0, "length": 183, "protein_name": "Family with sequence similarity 237 member A; Neurosecretory protein GL", "gene_name": "Fam237a", "organism": "Rat", "refseq_name": "protein FAM237A precursor", "refseq_ac": [ { "id": "NP_001388875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388875", "type": "external" } ], "gene_names_uniprotkb": "Fam237a; LOC103690541", "gene_names_refseq": "Fam237a; NPGL", "protein_names_uniprotkb": "Family with sequence similarity 237 member A; Neurosecretory protein GL", "protein_names_refseq": "neurosecretory protein GL; protein FAM237A precursor", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "25708449;28323972;28799896", "class_list": "", "function": "Distribution of NPGL in the mammalian brain and point to an important role for this neuropeptide in energy homeostasis., [RefSeq, PubMed]; The synthesis of the entire 80-amino acid peptide sequence of rat NPGL was optimized by microwave-assisted solid-phase peptide synthesis., [RefSeq, PubMed]; These results point to NPGL as a novel neuronal regulator that drives food intake and fat deposition through de novo lipogenesis and acts to maintain steady-state fat level in concert with insulin. Dysregulation of NPGL may be a root cause of obesity. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JTZ0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTZ2-1", "uniprot_id": [ { "id": "SOX6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTZ2", "type": "external" } ], "mass": 91816.0, "length": 827, "protein_name": "Transcription factor SOX-6", "gene_name": "Sox6", "organism": "Rat", "refseq_name": "transcription factor SOX-6", "refseq_ac": [ { "id": "NP_001019922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019922", "type": "external" } ], "gene_names_uniprotkb": "Sox6; Sox-6", "gene_names_refseq": "Sox6", "protein_names_uniprotkb": "Transcription factor SOX-6", "protein_names_refseq": "SRY (sex determining region Y)-box 6; SRY box 6; SRY-box containing gene 6; transcription factor SOX-6", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); heart disease (Disease Ontology:DOID:114); high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (rno:293165); (R-RNO-3769402)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "12081133;26150426;26659076;31076992;32114773", "class_list": "", "function": "LncRNA Gm4419 induces cell apoptosis in hepatic ischemia-reperfusion injury via regulating the miR-455-SOX6 axis., [RefSeq, PubMed]; Sox6 was specifically expressed in the neonatal brain and adult testis with Northern blotting., [RefSeq, PubMed]; The apoptosis process enhanced by overexpression of SOX6 or PDCD4, was rescued by the cardiac-abundant miR-499 in rat cardiomyocytes., [RefSeq, PubMed]; The authors proved that miR-499-5p inhibited hypoxia/reoxygenation-induced cardiomyocytes injury by targeting SOX6., [RefSeq, PubMed]; Transcription factor that plays a key role in several developmental processes, including neurogenesis, chondrocytes differentiation and cartilage formation (By similarity). Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis (By similarity). Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate (PubMed:26150426). Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes (By similarity). Together with SOX5, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts (By similarity). Binds to the proximal promoter region of the myelin protein MPZ gene, and is thereby involved in the differentiation of oligodendroglia in the developing spinal tube (By similarity). Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MAJ5;Q4V8G3", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm", "go_biological_process": "GO:0048708 astrocyte differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001701 in utero embryonic development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JTZ2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000001.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTZ6-1", "uniprot_id": [ { "id": "A0A0G2JTZ6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTZ6", "type": "external" } ], "mass": 98818.0, "length": 902, "protein_name": "Synphilin-1", "gene_name": "Sncaip", "organism": "Rat", "refseq_name": "synphilin-1 isoform 2", "refseq_ac": [ { "id": "NP_001424404", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424404", "type": "external" } ], "gene_names_uniprotkb": "Sncaip", "gene_names_refseq": "Sncaip; Syph1", "protein_names_uniprotkb": "Synphilin-1; Alpha-synuclein-interacting protein", "protein_names_refseq": "synphilin-1 isoform 2; synphilin-1; synuclein, alpha interacting protein (synphilin)", "tax_id": 10116, "disease": "", "pathway": " (rno:307309)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11956199;19224863", "class_list": "", "function": "Our data indicated that synphilin-1 is a synaptic partner of alpha-synuclein, and it may mediate synaptic roles attributed to alpha-synuclein. Erratum:[J Biol Chem 2002 Sep 13;277(37):34651-4], [RefSeq, PubMed]; Synphilin-1A has a novel role as a regulator of SIAH activity, modulating alpha-synuclein, and formation of Lewy body-like inclusions, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0046928 regulation of neurotransmitter secretion;GO:0042417 dopamine metabolic process;GO:0090083 regulation of inclusion body assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JTZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTZ7-1", "uniprot_id": [ { "id": "A0A0G2JTZ7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTZ7", "type": "external" } ], "mass": 41547.0, "length": 375, "protein_name": "Solute carrier family 35, member F2", "gene_name": "Slc35f2", "organism": "Rat", "refseq_name": "solute carrier family 35 member F2 isoform 1", "refseq_ac": [ { "id": "NP_001382663", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382663", "type": "external" } ], "gene_names_uniprotkb": "Slc35f2", "gene_names_refseq": "Slc35f2", "protein_names_uniprotkb": "Solute carrier family 35, member F2", "protein_names_refseq": "solute carrier family 35 member F2 isoform 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative solute transporter., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTZ7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTZ9-1", "uniprot_id": [ { "id": "A0A0G2JTZ9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTZ9", "type": "external" } ], "mass": 74656.0, "length": 661, "protein_name": "ATP-binding cassette, subfamily G (WHITE), member 3-like 3", "gene_name": "Abcg3l1; Abcg3l2; Abcg3l3; Abcg3l4; Abcg3; Gbp6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Abcg3l1; Abcg3l2; Abcg3l3; Abcg3l4; Abcg3; Gbp6; Abcg3l2; Abcg3l3; Abcg3l4; Abcg3; Gbp6-ps1; Gbp6; LOC100359633; LOC103690086; LOC360997; Mpa2l", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-binding cassette, subfamily G (WHITE), member 3-like 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "gout (Disease Ontology:DOID:13189); breast carcinoma (Disease Ontology:DOID:3459); toxic encephalopathy (Disease Ontology:DOID:3602); renal cell carcinoma (Disease Ontology:DOID:4450); B-cell lymphoma (Disease Ontology:DOID:707); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute megakaryocytic leukemia (Disease Ontology:DOID:8761); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:289453); (rno:305142); (rno:360997)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0044406 adhesion of symbiont to host;GO:0050830 defense response to Gram-positive bacterium;GO:0071346 cellular response to type II interferon;GO:0042832 defense response to protozoan;GO:0031347 regulation of defense response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTZ9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU02-1", "uniprot_id": [ { "id": "A0A0G2JU02_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU02", "type": "external" } ], "mass": 119227.0, "length": 1047, "protein_name": "Dermatan sulfate epimerase", "gene_name": "Dse", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dse", "gene_names_refseq": "", "protein_names_uniprotkb": "Dermatan sulfate epimerase", "protein_names_refseq": "", "tax_id": 10116, "disease": "Ehlers-Danlos syndrome musculocontractural type 2 (Disease Ontology:DOID:0080737)", "pathway": " (rno:365583)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0047757 chondroitin-glucuronate 5-epimerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0050651 dermatan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU02-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU09-1", "uniprot_id": [ { "id": "A0A0G2JU09_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU09", "type": "external" } ], "mass": 345089.0, "length": 3152, "protein_name": "E1A-binding protein p400", "gene_name": "Ep400", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ep400", "gene_names_refseq": "", "protein_names_uniprotkb": "E1A-binding protein p400; Domino homolog; p400 kDa SWI2/SNF2-related protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); developmental disorder of mental health (Disease Ontology:DOID:0060037)", "pathway": " (rno:304569); (R-RNO-2559584); (R-RNO-2559586)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:1990405 protein antigen binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000812 Swr1 complex;GO:0000786 nucleosome", "go_biological_process": "GO:0006325 chromatin organization;GO:0051726 regulation of cell cycle;GO:1905168 positive regulation of double-strand break repair via homologous recombination;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JU09-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU13-1", "uniprot_id": [ { "id": "A0A0G2JU13_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU13", "type": "external" } ], "mass": 33278.0, "length": 293, "protein_name": "C-type lectin domain family 4, member G", "gene_name": "Clec4g", "organism": "Rat", "refseq_name": "C-type lectin domain family 4 member G isoform X1", "refseq_ac": [ { "id": "XP_038945826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038945826", "type": "external" } ], "gene_names_uniprotkb": "Clec4g", "gene_names_refseq": "Clec4g", "protein_names_uniprotkb": "C-type lectin domain family 4, member G", "protein_names_refseq": "C-type lectin domain family 4 member G isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-198933)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0030246 carbohydrate binding;GO:0001618 virus receptor activity;GO:0070061 fructose binding;GO:0005537 D-mannose binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0002710 negative regulation of T cell mediated immunity;GO:0046633 alpha-beta T cell proliferation;GO:0006955 immune response;GO:0042130 negative regulation of T cell proliferation;GO:0046718 symbiont entry into host cell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU13-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU15-1", "uniprot_id": [ { "id": "A0A0G2JU15_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU15", "type": "external" } ], "mass": 78334.0, "length": 690, "protein_name": "Small ribosomal subunit protein mS39", "gene_name": "Ptcd3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ptcd3; LOC500199", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein mS39; 28S ribosomal protein S39, mitochondrial; Pentatricopeptide repeat 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"https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU41-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU45-1", "uniprot_id": [ { "id": "A0A0G2JU45_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU45", "type": "external" } ], "mass": 56453.0, "length": 496, "protein_name": "tRNA (guanine(37)-N1)-methyltransferase", "gene_name": "Trmt5", "organism": "Rat", "refseq_name": "tRNA (guanine(37)-N1)-methyltransferase isoform X1", "refseq_ac": [ { "id": "XP_038968435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038968435", "type": "external" } ], "gene_names_uniprotkb": "Trmt5; TRM5; TRMT5", "gene_names_refseq": "RGD1306567; Trmt5", "protein_names_uniprotkb": "tRNA (guanine(37)-N1)-methyltransferase; 2.1.1.228; M1G-methyltransferase; tRNA [GM37] methyltransferase; tRNA methyltransferase 5 homolog", "protein_names_refseq": "tRNA (guanine(37)-N1)-methyltransferase isoform X1", "tax_id": 10116, "disease": "mitochondrial complex I deficiency (Disease Ontology:DOID:0060536); mitochondrial complex III deficiency (Disease Ontology:DOID:0111139); combined oxidative phosphorylation deficiency 26 (Disease Ontology:DOID:0111490); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); hypercalcemia (Disease Ontology:DOID:12678); lactic acidosis (Disease Ontology:DOID:3650); cytochrome-c oxidase deficiency disease (Disease Ontology:DOID:3762); mitochondrial myopathy (Disease Ontology:DOID:699)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding., [UniProtKB, UniProtKB, UniProtKB]; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.228", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.228", "type": "external" } ], "go_molecular_function": "GO:0052906 tRNA (guanine(37)-N1)-methyltransferase activity;GO:0008175 tRNA methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix;GO:0005737 cytoplasm", "go_biological_process": "GO:0070901 mitochondrial tRNA methylation;GO:0002939 tRNA N1-guanine methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU45-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU49-1", "uniprot_id": [ { "id": "A0A0G2JU49_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU49", "type": "external" } ], "mass": 52989.0, "length": 472, "protein_name": "Metaxin-1", "gene_name": "Mtx1", "organism": "Rat", "refseq_name": "metaxin-1 isoform 1", "refseq_ac": [ { "id": "NP_001386168", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386168", "type": "external" } ], "gene_names_uniprotkb": "Mtx1", "gene_names_refseq": "Mtx1", "protein_names_uniprotkb": "Metaxin-1; Mitochondrial outer membrane import complex protein 1", "protein_names_refseq": "metaxin-1 isoform 1; metaxin-1", "tax_id": 10116, "disease": "", "pathway": " (rno:295241); (R-RNO-9013404)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Involved in transport of proteins into the mitochondrion. Essential for embryonic development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001401 SAM complex", "go_biological_process": "GO:0015031 protein transport;GO:0007595 lactation;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JU49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU54-1", "uniprot_id": [ { "id": "A0A0G2JU54_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU54", "type": "external" } ], "mass": 35718.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or8k30b", "organism": "Rat", "refseq_name": "olfactory receptor Olr502", "refseq_ac": [ { "id": "NP_001000311", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000311", "type": "external" } ], "gene_names_uniprotkb": "Or8k30b", "gene_names_refseq": "Olr502; Or8k30b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 502; olfactory receptor Olr502; olfactory receptor gene Olr502", "tax_id": 10116, "disease": "", "pathway": " (rno:295763)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU54-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU55-1", "uniprot_id": [ { "id": "A0A0G2JU55_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU55", "type": "external" } ], "mass": 13670.0, "length": 117, "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "gene_name": "Gabarapl4", "organism": "Rat", "refseq_name": "gamma-aminobutyric acid receptor-associated protein-like 2", "refseq_ac": [ { "id": "XP_038954120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038954120", "type": "external" } ], "gene_names_uniprotkb": "Gabarapl4; LOC120098596", "gene_names_refseq": "Gabarapl4", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor-associated protein-like 2; GABA(A) receptor-associated protein-like 2; Golgi-associated ATPase enhancer of 16 kDa", "protein_names_refseq": "gamma-aminobutyric acid receptor-associated protein-like 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0008429 phosphatidylethanolamine binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000421 autophagosome membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0000423 mitophagy;GO:0006995 cellular response to nitrogen starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU55-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU60-1", "uniprot_id": [ { "id": "A0A0G2JU60_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU60", "type": "external" } ], "mass": 57401.0, "length": 534, "protein_name": "Glucocorticoid-induced transcript 1 protein", "gene_name": "Glcci1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Glcci1", "gene_names_refseq": "", "protein_names_uniprotkb": "Glucocorticoid-induced transcript 1 protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); hypertension (Disease Ontology:DOID:10763); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JU60-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU68-1", "uniprot_id": [ { "id": "A0A0G2JU68_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU68", "type": "external" } ], "mass": 198559.0, "length": 1788, "protein_name": "Pappalysin 2", "gene_name": "Pappa2", "organism": "Rat", "refseq_name": "pappalysin-2 precursor", "refseq_ac": [ { "id": "NP_001414707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414707", "type": "external" } ], "gene_names_uniprotkb": "Pappa2", "gene_names_refseq": "Pappa2", "protein_names_uniprotkb": "Pappalysin 2", "protein_names_refseq": "pappalysin-2 precursor", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-381426)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26534937", "class_list": "", "function": "A variant form of Pappa2 that can protect against salt-induced hypertension in the Dahl S rat, was identified., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007166 cell surface receptor signaling pathway;GO:0009651 response to salt stress;GO:0060349 bone morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JU68-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU91-1", "uniprot_id": [ { "id": "A0A0G2JU91_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU91", "type": "external" } ], "mass": 277616.0, "length": 2546, "protein_name": "Nuclear receptor corepressor 2", "gene_name": "Ncor2", "organism": "Rat", "refseq_name": "nuclear receptor corepressor 2 isoform X44", "refseq_ac": [ { "id": "XP_017453886", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017453886", "type": "external" } ], "gene_names_uniprotkb": "Ncor2", "gene_names_refseq": "Ncor2", "protein_names_uniprotkb": "Nuclear receptor corepressor 2; Silencing mediator of retinoic acid and thyroid hormone receptor; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor", "protein_names_refseq": "nuclear receptor corepressor 2 isoform X44", "tax_id": 10116, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); breast cancer (Disease Ontology:DOID:1612); endometrial carcinoma (Disease Ontology:DOID:2871); myelofibrosis (Disease Ontology:DOID:4971); osteoarthritis (Disease Ontology:DOID:8398)", "pathway": " (R-RNO-2173795); (R-RNO-3214815); (R-RNO-350054); (R-RNO-381340); (R-RNO-383280); (R-RNO-400206); (R-RNO-9029569); (R-RNO-9623433); (R-RNO-9707564); (R-RNO-9841922)", "pathway_count": 10, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "Transcriptional corepressor that mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Acts by recruiting chromatin modifiers, such as histone deacetylases HDAC1, HDAC2 and HDAC3. Required to activate the histone deacetylase activity of HDAC3. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008047 enzyme activator activity;GO:0003714 transcription corepressor activity;GO:0035259 nuclear glucocorticoid receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0016604 nuclear body;GO:0016363 nuclear matrix;GO:0000785 chromatin", "go_biological_process": "GO:0010565 regulation of ketone metabolic process;GO:0060816 random inactivation of X chromosome;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001701 in utero embryonic development;GO:0030900 forebrain development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JU91-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU98-1", "uniprot_id": [ { "id": "A0A0G2JU98_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU98", "type": "external" } ], "mass": 48303.0, "length": 439, "protein_name": "SH3 and cysteine-rich domain-containing protein 2", "gene_name": "Stac2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Stac2", "gene_names_refseq": "", "protein_names_uniprotkb": "SH3 and cysteine-rich domain-containing protein 2; 24b2/STAC2; Src homology 3 and cysteine-rich domain-containing protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0042383 sarcolemma;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0003009 skeletal muscle contraction;GO:1903078 positive regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JU98-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUC0-1", "uniprot_id": [ { "id": "A0A0G2JUC0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUC0", "type": "external" } ], "mass": 77687.0, "length": 697, "protein_name": "Macrophage-expressed gene 1 protein", "gene_name": "Pfpl", "organism": "Rat", "refseq_name": "pore forming protein-like precursor", "refseq_ac": [ { "id": "NP_001388782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388782", "type": "external" } ], "gene_names_uniprotkb": "Pfpl", "gene_names_refseq": "Pfpl; RGD1564458", "protein_names_uniprotkb": "Macrophage-expressed gene 1 protein; Perforin-2", "protein_names_refseq": "pore forming protein-like precursor", "tax_id": 10116, "disease": "primary immunodeficiency disease (Disease Ontology:DOID:612)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pore-forming protein involved in both innate and adaptive immunity. Plays a central role in antigen cross-presentation in dendritic cells by forming a pore in antigen-containing compartments, thereby promoting delivery of antigens for cross-presentation. Also involved in innate immune response following bacterial infection; shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria. Reduces the viability of the intracytosolic pathogen L.monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol. Required for the antibacterial activity of reactive oxygen species and nitric oxide., [UniProtKB, UniProtKB]; Pore-forming protein that plays a central role in antigen cross-presentation in dendritic cells by mediating delivery of antigens for cross-presentation. Dendritic cells bridge innate and adaptive immunity by capturing exogenous antigens on MHC class-I molecules and presenting them to naive CD8(+) T-cells. Acts by forming a pore in antigen-containing compartments, promoting the release of antigens into the cytosol, enabling generation of MHCI:peptide complexes and T-cell priming., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JUC0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUC1-1", "uniprot_id": [ { "id": "A0A0G2JUC1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUC1", "type": "external" } ], "mass": 42052.0, "length": 398, "protein_name": "Sp5 transcription factor", "gene_name": "Sp5", "organism": "Rat", "refseq_name": "transcription factor Sp5", "refseq_ac": [ { "id": "NP_001100022", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100022", "type": "external" } ], "gene_names_uniprotkb": "Sp5", "gene_names_refseq": "Sp5", "protein_names_uniprotkb": "Sp5 transcription factor", "protein_names_refseq": "trans-acting transcription factor 5; transcription factor Sp5", "tax_id": 10116, "disease": "", "pathway": " (rno:296510)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0060349 bone morphogenesis;GO:0036342 post-anal tail morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JUC1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUC2-1", "uniprot_id": [ { "id": "A0A0G2JUC2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUC2", "type": "external" } ], "mass": 34616.0, "length": 310, "protein_name": "Olfactory receptor family 10 subfamily G member 9B", "gene_name": "Or10g9b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1335", "refseq_ac": [ { "id": "NP_001000479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000479", "type": "external" } ], "gene_names_uniprotkb": "Or10g9b", "gene_names_refseq": "Olr1335; Or10g9b", "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily G member 9B", "protein_names_refseq": "olfactory receptor 1335; olfactory receptor Olr1335; olfactory receptor gene Olr1335", "tax_id": 10116, "disease": "", "pathway": " (rno:300635)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JUC2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUC8-1", "uniprot_id": [ { "id": "A0A0G2JUC8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUC8", "type": "external" } ], "mass": 13132.0, "length": 114, "protein_name": "E3 ubiquitin-protein ligase RBX1", "gene_name": "Rbx1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rbx1", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RBX1; 2.3.2.32; E3 ubiquitin-protein transferase RBX1; RING finger protein 75; RING-box protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (R-RNO-110314); (R-RNO-1170546); (R-RNO-1234176); (R-RNO-195253); (R-RNO-4641258); (R-RNO-5610780); (R-RNO-5610785); (R-RNO-5632684); (R-RNO-5658442); (R-RNO-5696394); (R-RNO-5696395); (R-RNO-5696400); (R-RNO-6781823); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-68949); (R-RNO-69601); (R-RNO-8854050); (R-RNO-8951664); (R-RNO-9020702); (R-RNO-9755511); (R-RNO-9762114); (R-RNO-983168); (R-RNO-9929356); (R-RNO-9929491); (R-RNO-9954709)", "pathway_count": 26, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.4.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.30", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "1.14.11.29", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.29", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" } ], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0044877 protein-containing complex binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0030891 VCB complex;GO:0031467 Cul7-RING ubiquitin ligase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0007283 spermatogenesis;GO:0042110 T cell activation;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JUC8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUC9-1", "uniprot_id": [ { "id": "A0A0G2JUC9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUC9", "type": "external" } ], "mass": 527477.0, "length": 4836, "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "Herc2", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase HERC2", "refseq_ac": [ { "id": "XP_006229362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229362", "type": "external" } ], "gene_names_uniprotkb": "Herc2", "gene_names_refseq": "Herc2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HERC2; 2.3.2.26; HECT domain and RCC1-like domain-containing protein 2; HECT-type E3 ubiquitin transferase HERC2", "protein_names_refseq": "E3 ubiquitin-protein ligase HERC2; hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2; hect domain and RLD 2; probable E3 ubiquitin-protein ligase HERC2", "tax_id": 10116, "disease": "autosomal recessive intellectual developmental disorder 38 (Disease Ontology:DOID:0081203); pigmentation disease (Disease Ontology:DOID:10123)", "pathway": " (R-RNO-3108214); (R-RNO-5693565); (R-RNO-5693571); (R-RNO-5693607); (R-RNO-69473); (R-RNO-983168)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "E3 ubiquitin-protein ligase that regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes. Recruited to sites of DNA damage in response to ionizing radiation (IR) and facilitates the assembly of UBE2N and RNF8 promoting DNA damage-induced formation of 'Lys-63'-linked ubiquitin chains. Acts as a mediator of binding specificity between UBE2N and RNF8. Involved in the maintenance of RNF168 levels. E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of XPA which influences the circadian oscillation of DNA excision repair activity. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Also modulates iron metabolism by regulating the basal turnover of FBXL5., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "1.14.11.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.14.11.69", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.69", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0061630 ubiquitin protein ligase activity;GO:0032183 SUMO binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005814 centriole;GO:0016020 membrane", "go_biological_process": "GO:0006281 DNA repair;GO:0007283 spermatogenesis;GO:0006974 DNA damage response;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JUC9-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUD6-1", "uniprot_id": [ { "id": "A0A0G2JUD6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUD6", "type": "external" } ], "mass": 78522.0, "length": 686, "protein_name": "Kinesin-like protein", "gene_name": "Kif3a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kif3a", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "polycystic kidney disease (Disease Ontology:DOID:0080322); silicosis (Disease Ontology:DOID:10325); dysostosis (Disease Ontology:DOID:1934)", "pathway": " (R-RNO-2132295); (R-RNO-5610787); (R-RNO-5620924); (R-RNO-6811434); (R-RNO-983189)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0030507 spectrin binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0034021 response to silicon dioxide;GO:0001701 in utero embryonic development;GO:0007507 heart development;GO:0015031 protein transport;GO:0030900 forebrain development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JUD6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUE9-1", "uniprot_id": [ { "id": "A0A0G2JUE9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9", "type": "external" } ], "mass": 34614.0, "length": 312, "protein_name": "Olfactory receptor family 5 subfamily B member 95 like 1", "gene_name": "Or5b104b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or5b104b; 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[ { "id": "A0A0G2JV19_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV19", "type": "external" } ], "mass": 104266.0, "length": 922, "protein_name": "Transforming growth factor, beta receptor associated protein 1", "gene_name": "Tgfbrap1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tgfbrap1", "gene_names_refseq": "", "protein_names_uniprotkb": "Transforming growth factor, beta receptor associated protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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cytoplasm", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007165 signal transduction;GO:0006355 regulation of DNA-templated transcription;GO:0008333 endosome to lysosome transport;GO:0034058 endosomal vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JV19-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV23-1", "uniprot_id": [ { "id": "A0A0G2JV23_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV23", "type": "external" } ], "mass": 77191.0, "length": 659, "protein_name": "Zinc finger protein 600", "gene_name": "Zfp758", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp758; Zfp600", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 600", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:690559); (R-RNO-212436); (R-RNO-9843940)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV24-1", "uniprot_id": [ { "id": "A0A0G2JV24_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV24", "type": "external" } ], "mass": 129806.0, "length": 1171, "protein_name": "Thrombospondin-1", "gene_name": "Thbs1", "organism": "Rat", "refseq_name": "thrombospondin-1 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001385869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385869", "type": "external" } ], "gene_names_uniprotkb": "Thbs1", "gene_names_refseq": "TSP-1; Thbs1; Tsp1", "protein_names_uniprotkb": "Thrombospondin-1; Glycoprotein G", "protein_names_refseq": "thrombospondin-1 isoform 2 precursor", "tax_id": 10116, "disease": "COVID-19 (Disease Ontology:DOID:0080600); prostate cancer (Disease Ontology:DOID:10283); primary open angle glaucoma (Disease Ontology:DOID:1070); urinary bladder cancer (Disease Ontology:DOID:11054); heart disease (Disease Ontology:DOID:114); Sjogren's syndrome (Disease Ontology:DOID:12894); pancreatic cancer (Disease Ontology:DOID:1793); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); cholangiocarcinoma (Disease Ontology:DOID:4947); myocardial infarction (Disease Ontology:DOID:5844); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); obesity (Disease Ontology:DOID:9970)", "pathway": " (R-RNO-114608); (R-RNO-186797); (R-RNO-216083); (R-RNO-5173214)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "36920202;37573658;38108523;38237742;38439091", "class_list": "", "function": "Exosomes derived from menstrual blood stromal cells ameliorated premature ovarian insufficiency and granulosa cell apoptosis by regulating SMAD3/AKT/MDM2/P53 pathway via delivery of thrombospondin-1., [RefSeq, PubMed]; RNF7 Induces Skeletal Muscle Cell Apoptosis and Arrests Cell Autophagy via Upregulation of THBS1 and Inactivation of the PI3K/Akt Signaling Pathway in a Rat Sepsis Model., [RefSeq, PubMed]; Targeting Thbs1 reduces bladder remodeling caused by partial bladder outlet obstruction via the FGFR3/p-FGFR3 pathway., [RefSeq, PubMed]; Thrombospondin 1 enhances systemic inflammation and disease severity in acute-on-chronic liver failure. Publication Status: Online-Only, [RefSeq, PubMed]; Thrombospondin-1-mediated crosstalk between autophagy and oxidative stress orchestrates repair of blast lung injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0030141 secretory granule;GO:0031012 extracellular matrix", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0032693 negative regulation of interleukin-10 production;GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JV24-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV25-1", "uniprot_id": [ { "id": "A0A0G2JV25_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV25", "type": "external" } ], "mass": 9918.0, "length": 82, "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064690", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000064690", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JV25-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV35-1", "uniprot_id": [ { "id": "A0A0G2JV35_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV35", "type": "external" } ], "mass": 34222.0, "length": 312, "protein_name": "N-alpha-acetyltransferase 80", "gene_name": "Naa80", "organism": "Rat", "refseq_name": "N-alpha-acetyltransferase 80", "refseq_ac": [ { "id": "NP_001291705", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291705", "type": "external" } ], "gene_names_uniprotkb": "Naa80", "gene_names_refseq": "Naa80; Nat6", "protein_names_uniprotkb": "N-alpha-acetyltransferase 80; N-acetyltransferase 6", "protein_names_refseq": "N-acetyltransferase 6 (GCN5-related); N-acetyltransferase 6-like; N-alpha-acetyltransferase 80", "tax_id": 10116, "disease": "", "pathway": " (rno:100910872)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively). N-terminal acetylation of processed beta- and gamma-actin regulates actin filament depolymerization and elongation. In vivo, preferentially displays N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu. In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp. May act as a tumor suppressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, 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Kb15", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin 90", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0045095 keratin filament", "go_biological_process": "GO:0031424 keratinization;GO:0045109 intermediate filament organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVA8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVC1-1", "uniprot_id": [ { "id": "A0A0G2JVC1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVC1", "type": "external" } ], "mass": 53902.0, "length": 483, "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "Mdm2", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase Mdm2", "refseq_ac": [ { "id": "XP_038935055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038935055", "type": "external" } ], "gene_names_uniprotkb": "Mdm2", "gene_names_refseq": "Mdm2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Mdm2; 2.3.2.27; Double minute 2 protein; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2", "protein_names_refseq": "E3 ubiquitin-protein ligase Mdm2; MDM2 oncogene, E3 ubiquitin protein ligase; MDM2 proto-oncogene, E3 ubiquitin protein ligase; Mdm2 p53 binding protein homolog; double minute 2; p53 E3 ubiquitin protein ligase; transformed mouse 3T3 cell double minute 2", "tax_id": 10116, "disease": "biliary tract benign neoplasm (Disease Ontology:DOID:0050625); urinary bladder cancer (Disease Ontology:DOID:11054); sarcoma (Disease Ontology:DOID:1115); breast cancer (Disease Ontology:DOID:1612); ichthyosis (Disease Ontology:DOID:1697); post-traumatic stress disorder (Disease Ontology:DOID:2055); transient cerebral ischemia (Disease Ontology:DOID:224); glioblastoma (Disease Ontology:DOID:3068); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); intermittent claudication (Disease Ontology:DOID:3669); liver disease (Disease Ontology:DOID:409); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute myeloid leukemia (Disease Ontology:DOID:9119); priapism (Disease Ontology:DOID:9286)", "pathway": " (rno:314856)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0043021 ribonucleoprotein complex binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0003170 heart valve development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JVC1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVC4-1", "uniprot_id": [ { "id": "A0A0G2JVC4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVC4", "type": "external" } ], "mass": 58635.0, "length": 510, "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "Cgas", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cgas", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclic GMP-AMP synthase; 2'3'-cGAMP synthase; 2.7.7.86; Mab-21 domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.86", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.86", "type": "external" } ], "go_molecular_function": "GO:0061501 2',3'-cyclic GMP-AMP synthase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016604 nuclear body", "go_biological_process": "GO:0071360 cellular response to exogenous dsRNA;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0002221 pattern recognition receptor signaling pathway;GO:0002637 regulation of immunoglobulin production;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVC4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVD2-1", "uniprot_id": [ { "id": "A0A0G2JVD2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVD2", "type": "external" } ], "mass": 52483.0, "length": 467, "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "gene_name": "Slc25a23", "organism": "Rat", "refseq_name": "mitochondrial adenyl nucleotide antiporter SLC25A23", "refseq_ac": [ { "id": "NP_001100343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100343", "type": "external" } ], "gene_names_uniprotkb": "Slc25a23", "gene_names_refseq": "Slc25a23", "protein_names_uniprotkb": "Mitochondrial adenyl nucleotide antiporter SLC25A23; Short calcium-binding mitochondrial carrier protein 3; Solute carrier family 25 member 23", "protein_names_refseq": "calcium-binding mitochondrial carrier protein SCaMC-3; mitochondrial adenyl nucleotide antiporter SLC25A23; phosphate carrier), member 23; solute carrier family 25 (mitochondrial carrier", "tax_id": 10116, "disease": "", "pathway": " (rno:301113)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways. Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0000295 adenine nucleotide transmembrane transporter activity;GO:0005347 ATP transmembrane transporter activity;GO:0140987 ATP:phosphate antiporter activity;GO:0140988 ADP:phosphate antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0043457 regulation of cellular respiration;GO:0071277 cellular response to calcium ion;GO:0006851 mitochondrial calcium ion transmembrane transport;GO:0015866 ADP transport;GO:0036444 calcium import into the mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVD2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVD5-1", "uniprot_id": [ { "id": "A0A0G2JVD5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVD5", "type": "external" } ], "mass": 207428.0, "length": 1859, "protein_name": "Zinc finger protein 142", "gene_name": "Zfp142", "organism": "Rat", "refseq_name": "zinc finger protein 142 isoform 1", "refseq_ac": [ { "id": "NP_001418925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418925", "type": "external" } ], "gene_names_uniprotkb": "Zfp142", "gene_names_refseq": "Zfp142; Znf142", "protein_names_uniprotkb": "Zinc finger protein 142", "protein_names_refseq": "zinc finger protein 142 (clone pHZ-49); zinc finger protein 142 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:316524)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVD5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVD6-1", "uniprot_id": [ { "id": "A0A0G2JVD6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVD6", "type": "external" } ], "mass": 595654.0, "length": 5544, "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "Kmt2d", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase 2D isoform X11", "refseq_ac": [ { "id": "XP_017450810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017450810", "type": "external" } ], "gene_names_uniprotkb": "Kmt2d", "gene_names_refseq": "Kmt2d; Mll2", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase 2D; 2.1.1.364; ALL1-related protein; Myeloid/lymphoid or mixed-lineage leukemia protein 2", "protein_names_refseq": "histone-lysine N-methyltransferase 2D isoform X11", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Kabuki syndrome (Disease Ontology:DOID:0060473); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); intracranial aneurysm (Disease Ontology:DOID:10941); colon carcinoma (Disease Ontology:DOID:1520); breast cancer (Disease Ontology:DOID:1612); breast carcinoma (Disease Ontology:DOID:3459); meningioma (Disease Ontology:DOID:3565); gastric adenocarcinoma (Disease Ontology:DOID:3717); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); papillary thyroid carcinoma (Disease Ontology:DOID:3969); lung small cell carcinoma (Disease Ontology:DOID:5409); gastrointestinal lymphoma (Disease Ontology:DOID:903)", "pathway": " (R-RNO-3214841); (R-RNO-8936459); (R-RNO-9772755)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 13, "predicted_n_glycosites": 0, "predicted_o_glycosites": 13, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" }, { "id": "2.1.1.371", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.371", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.85", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0042800 histone H3K4 methyltransferase activity", "go_cellular_component": "GO:0044666 MLL3/4 complex", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043627 response to estrogen;GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JVD6-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVD9-1", "uniprot_id": [ { "id": "A0A0G2JVD9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVD9", "type": "external" } ], "mass": 62051.0, "length": 562, "protein_name": "IKAROS family zinc finger 1", "gene_name": "Ikzf1", "organism": "Rat", "refseq_name": "DNA-binding protein Ikaros isoform X1", "refseq_ac": [ { "id": "XP_006251556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006251556", "type": "external" } ], "gene_names_uniprotkb": "Ikzf1", "gene_names_refseq": "Ikzf1; RGD1562979", "protein_names_uniprotkb": "IKAROS family zinc finger 1", "protein_names_refseq": "DNA-binding protein Ikaros isoform X1", "tax_id": 10116, "disease": "B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); common variable immunodeficiency 13 (Disease Ontology:DOID:0081155); lung adenocarcinoma (Disease Ontology:DOID:3910); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0032993 protein-DNA complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0001779 natural killer cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0030900 forebrain development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JVD9-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVF0-1", "uniprot_id": [ { "id": "A0A0G2JVF0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVF0", "type": "external" } ], "mass": 107336.0, "length": 965, "protein_name": "Rho GTPase activating protein 4", "gene_name": "Arhgap4", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 4", "refseq_ac": [ { "id": "NP_653341", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_653341", "type": "external" } ], "gene_names_uniprotkb": "Arhgap4", "gene_names_refseq": "Arhgap4", "protein_names_uniprotkb": "Rho GTPase activating protein 4", "protein_names_refseq": "rho GTPase-activating protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:246249); (R-RNO-8980692); (R-RNO-9013148); (R-RNO-9013149)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12414125;17804252;22673903", "class_list": "", "function": "ARHGAP4 occured in the hippocampus, ventral region of the brainstem and striatum, and in cerebellar granule cells. Subcellularly, ARHGAP4 localized to the Golgi complex and could redistribute to the microtubules, for example during mitosis., [RefSeq, PubMed]; These observations suggest that ARHGAP4 can act as a potent inhibitor of cell and axon motility when it is localized to the leading edge of motile cells and axons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005874 microtubule;GO:0030426 growth cone;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0010764 negative regulation of fibroblast migration;GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0035023 regulation of Rho protein signal transduction;GO:0030517 negative regulation of axon extension", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JVF0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVF5-1", "uniprot_id": [ { "id": "A0A0G2JVF5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVF5", "type": "external" } ], "mass": 42535.0, "length": 384, "protein_name": "High mobility group protein B3", "gene_name": "Hmgb3l1; Hmgb3", "organism": "Rat", "refseq_name": "high mobility group protein B3 isoform 3", "refseq_ac": [ { "id": "NP_001385706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385706", "type": "external" } ], "gene_names_uniprotkb": "Hmgb3l1; Hmgb3; Hmgb3l1; LOC108348204", "gene_names_refseq": "Hmgb3; RGD1564407", "protein_names_uniprotkb": "High mobility group protein B3; High mobility group protein 2a; High mobility group protein 4", "protein_names_refseq": "high mobility group protein B3 isoform 3; high mobility group protein B3", "tax_id": 10116, "disease": "syndromic microphthalmia 13 (Disease Ontology:DOID:0111811)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "30166860;32587254", "class_list": "", "function": "HMGB3 is involved in malignant transformation of hepatocytes and could be a useful biomarker for diagnosis and a potential target for therapy of liver cancer., [RefSeq, PubMed]; MiR-200b in heme oxygenase-1-modified bone marrow mesenchymal stem cell-derived exosomes alleviates inflammatory injury of intestinal epithelial cells by targeting high mobility group box 3. Publication Status: Online-Only, [RefSeq, PubMed]; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference for non-canonical DNA structures such as single-stranded DNA. Can bend DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0045087 innate immune response;GO:0045638 negative regulation of myeloid cell differentiation;GO:0045578 negative regulation of B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JVF5-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVF7-1", "uniprot_id": [ { "id": "A0A0G2JVF7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVF7", "type": "external" } ], "mass": 34597.0, "length": 339, "protein_name": "Keratin associated like protein 29-1", "gene_name": "Krtap29-1", "organism": "Rat", "refseq_name": "keratin-associated protein 29-1", "refseq_ac": [ { "id": "XP_038943775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943775", "type": "external" } ], "gene_names_uniprotkb": "Krtap29-1", "gene_names_refseq": "Krtap29-1", "protein_names_uniprotkb": "Keratin associated like protein 29-1", "protein_names_refseq": "keratin-associated protein 29-1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6805567)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVF7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVG6-1", "uniprot_id": [ { "id": "A0A0G2JVG6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVG6", "type": "external" } ], "mass": 80875.0, "length": 690, "protein_name": "Zinc finger protein 59", "gene_name": "Zfp59", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp59", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 59", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVG6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVH3-1", "uniprot_id": [ { "id": "A0A0G2JVH3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVH3", "type": "external" } ], "mass": 46988.0, "length": 412, "protein_name": "Leukocyte immunoglobulin like receptor B4", "gene_name": "Lilrb4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lilrb4", "gene_names_refseq": "", "protein_names_uniprotkb": "Leukocyte immunoglobulin like receptor B4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:292594)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle., [UniProtKB, UniProtKB, UniProtKB]; SPINK3 along with Ccna2 and EGFR accelerated cell proliferation during rat liver regeneration via P38 MAPK, PKC, JAK-STAT and AKT pathways., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0043687 post-translational protein modification;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JVY9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVZ2-1", "uniprot_id": [ { "id": "A0A0G2JVZ2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVZ2", "type": "external" } ], "mass": 30406.0, "length": 284, "protein_name": "T-cell leukemia homeobox 2", "gene_name": "Tlx2", "organism": "Rat", "refseq_name": "T-cell leukemia homeobox protein 2", "refseq_ac": [ { "id": "NP_001165596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165596", "type": "external" } ], "gene_names_uniprotkb": "Tlx2", "gene_names_refseq": "Hox11L.1; 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Primarily expressed in dendritic cells and macrophages, inhibits both canonical and non-canonical NF-kappa-B and ERK activation pathways. Functions as a negative regulator of NOD2 by targeting it to degradation via the proteasome pathway. In turn, promotes bacterial tolerance. Also inhibits the RIGI-mediated immune signaling against RNA viruses by reducing the E3 ubiquitin ligase TRIM25-mediated 'Lys-63'-linked RIGI activation but enhancing the E3 ubiquitin ligase RNF125-mediated 'Lys-48'-linked RIGI degradation. 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"tax_id": 10116, "disease": "acute promyelocytic leukemia (Disease Ontology:DOID:0060318); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); mood disorder (Disease Ontology:DOID:3324)", "pathway": " (rno:24705); (R-RNO-383280); (R-RNO-4090294); (R-RNO-5362517); (R-RNO-9616222)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "28570942;28645189;32205185;33411644;36768908", "class_list": "", "function": "Activation of the RARalpha Attenuated CSF Hypersecretion to Inhibit Hydrocephalus Development via Regulating the MAFB/MSR1 Pathway. Publication Status: Online-Only, [RefSeq, PubMed]; Data show that retinoic acid receptor alpha (RARalpha) improved the renal function and attenuated the progression of glomerulosclerosis (GS) that was associated with the over-expression of matrix metalloproteinases MMP2 and MMP9., [RefSeq, PubMed]; Data suggest that marginal vitamin A deficiency in pregnant rats down-regulates expression of Rara in hippocampal neurons of offspring leading to decreases in Src and Nr1 expression and causing learning and memory deficits in offspring. (Rara = retinoic acid receptor alpha; Src = proto-oncogene protein src; Nr1 = N-methyl-D-asparate receptor Nr1a), [RefSeq, PubMed]; Retinoic acid receptor alpha activation is necessary and sufficient for plasticity induced by recurrent central apnea., [RefSeq, PubMed]; Vitamin A regulates neural stem cell proliferation in rats after hypoxic-ischemic brain damage via RARa-mediated modulation of the beta-catenin pathway., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0032736 positive regulation of interleukin-13 production;GO:0032754 positive regulation of interleukin-5 production;GO:1901532 regulation of hematopoietic progenitor cell differentiation;GO:0002068 glandular epithelial cell development;GO:0060010 Sertoli cell fate commitment", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JW78-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JW81-1", "uniprot_id": [ { "id": "A0A0G2JW81_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JW81", "type": "external" } ], "mass": 13017.0, "length": 111, "protein_name": "Membrane-spanning 4-domains, subfamily A, member 19", "gene_name": "Ms4a19", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ms4a19; LOC100912336", "gene_names_refseq": "", "protein_names_uniprotkb": "Membrane-spanning 4-domains, subfamily A, member 19", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW81-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JW89-1", "uniprot_id": [ { "id": "A0A0G2JW89_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JW89", "type": "external" } ], "mass": 35294.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or8g50b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1318", "refseq_ac": [ { "id": "NP_001001087", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001087", "type": "external" } ], "gene_names_uniprotkb": "Or8g50b", "gene_names_refseq": "Olr1318; Or8g50b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1318; olfactory receptor Olr1318; olfactory receptor gene Olr1318", "tax_id": 10116, "disease": "", "pathway": " (rno:405980)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Initiates inward plasma membrane bending and recruitment of Bin/amphiphysin/Rvs (BAR) domain-containing proteins involved in membrane tubulation and cell trafficking. Facilitates ITGB1/beta1 integrin endocytosis, delaying cell adhesion and cell spreading on extracellular matrix. 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"hit_score": 0.2, "record_id": "A0A0G2JWW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWX2-1", "uniprot_id": [ { "id": "A0A0G2JWX2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX2", "type": "external" } ], "mass": 345800.0, "length": 3139, "protein_name": "Laminin subunit alpha-2", "gene_name": "Lama2", "organism": "Rat", "refseq_name": "laminin subunit alpha-2 precursor", "refseq_ac": [ { "id": "NP_001413968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001413968", "type": "external" } ], "gene_names_uniprotkb": "Lama2", "gene_names_refseq": "Lama2", "protein_names_uniprotkb": "Laminin subunit alpha-2; Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain", "protein_names_refseq": "laminin subunit alpha-2 precursor; laminin, alpha 2", "tax_id": 10116, "disease": "autosomal recessive limb-girdle muscular dystrophy type 23 (Disease Ontology:DOID:0061132); congenital merosin-deficient muscular dystrophy 1A (Disease Ontology:DOID:0110636); myopia (Disease Ontology:DOID:11830); renovascular hypertension (Disease Ontology:DOID:1591); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "27815338", "class_list": "", "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Laminin alpha2 in the basement membrane (BM) seems to play a crucial role in the blood-testis barrier-BM axis by modulating BTB dynamics during spermatogenesis., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0031594 neuromuscular junction;GO:0043197 dendritic spine;GO:0043083 synaptic cleft;GO:0042383 sarcolemma;GO:0005604 basement membrane", "go_biological_process": "GO:0032224 positive regulation of synaptic transmission, cholinergic;GO:0007155 cell adhesion;GO:0030155 regulation of cell adhesion;GO:0009887 animal organ morphogenesis;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JWX2-1", "record_type": "protein", "filter_code": "0000000.0000110.001000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWX9-1", "uniprot_id": [ { "id": "A0A0G2JWX9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX9", "type": "external" } ], "mass": 99827.0, "length": 910, "protein_name": "Calcium-activated chloride channel regulator 1", "gene_name": "Clca1", "organism": "Rat", "refseq_name": "calcium-activated chloride channel regulator 1 precursor", "refseq_ac": [ { "id": "NP_001100919", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100919", "type": "external" } ], "gene_names_uniprotkb": "Clca1", "gene_names_refseq": "Clca1; Clca3", "protein_names_uniprotkb": "Calcium-activated chloride channel regulator 1", "protein_names_refseq": "calcium-activated chloride channel regulator 1 precursor; calcium-activated chloride channel regulator 1; chloride channel calcium activated 3", "tax_id": 10116, "disease": "cystic fibrosis (Disease Ontology:DOID:1485); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (rno:308015); (R-RNO-2672351)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19558866;26510883", "class_list": "", "function": "Amino acids H159 and E167 in the rbCLCA1 metalloprotease motif are important in rbCLCA1 processing for localization to the cell surface., [RefSeq, PubMed]; Dexamethasone substantially downregulates the expression of CLCA3 mRNA and Muc5ac protein in nasal mucosa in allergic rhinitis., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030141 secretory granule;GO:0005902 microvillus", "go_biological_process": "GO:0006508 proteolysis;GO:0006816 calcium ion transport;GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JWX9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWY3-1", "uniprot_id": [ { "id": "A0A0G2JWY3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWY3", "type": "external" } ], "mass": 78716.0, "length": 700, "protein_name": "Solute carrier organic anion transporter family, member 6d1", "gene_name": "Slco6d1", "organism": "Rat", "refseq_name": "solute carrier organic anion transporter family, member 6d1", "refseq_ac": [ { "id": "NP_001397194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001397194", "type": "external" } ], "gene_names_uniprotkb": "Slco6d1", "gene_names_refseq": "Slco6d1", "protein_names_uniprotkb": "Solute carrier organic anion transporter family, member 6d1", "protein_names_refseq": "solute carrier organic anion transporter family, member 6d1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015347 sodium-independent organic anion transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0043252 sodium-independent organic anion transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWY3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWZ0-1", "uniprot_id": [ { "id": "A0A0G2JWZ0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWZ0", "type": "external" } ], "mass": 9042.0, "length": 79, "protein_name": "Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258", "gene_name": "Tmem258l4", "organism": "Rat", "refseq_name": "transmembrane protein 258-like", "refseq_ac": [ { "id": "XP_063136499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063136499", "type": "external" } ], "gene_names_uniprotkb": "Tmem258l4; AABR07040624.1", "gene_names_refseq": "Tmem258l4", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258; Transmembrane protein 258", "protein_names_refseq": "transmembrane protein 258-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0062062 oligosaccharyltransferase complex binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWZ0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWZ3-1", "uniprot_id": [ { "id": "A0A0G2JWZ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWZ3", "type": "external" } ], "mass": 96975.0, "length": 846, "protein_name": "Gamma-secretase activating protein", "gene_name": "Gsap", "organism": "Rat", "refseq_name": "gamma-secretase-activating protein", "refseq_ac": [ { "id": "NP_001381957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381957", "type": "external" } ], "gene_names_uniprotkb": "Gsap", "gene_names_refseq": "Gsap; Pion", "protein_names_uniprotkb": "Gamma-secretase activating protein", "protein_names_refseq": "gamma-secretase-activating protein; protein pigeon homolog", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23209290", "class_list": "", "function": "Gamma-secretase activating protein (GSAP) and imatinib have roles in the regulation of gamma-secretase activity and amyloid-beta generation, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0005802 trans-Golgi network", "go_biological_process": "GO:1902004 positive regulation of amyloid-beta formation;GO:0030162 regulation of proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JWZ3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWZ6-1", "uniprot_id": [ { "id": "A0A0G2JWZ6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWZ6", "type": "external" } ], "mass": 34826.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5p79", "organism": "Rat", "refseq_name": "olfactory receptor Olr272", "refseq_ac": [ { "id": "NP_001000230", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000230", "type": "external" } ], "gene_names_uniprotkb": "Or5p79", "gene_names_refseq": "Olr272; Or5p79", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 272; olfactory receptor Olr272; olfactory receptor gene Olr272", "tax_id": 10116, "disease": "", "pathway": " (rno:293439)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWZ6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX07-1", "uniprot_id": [ { "id": "A0A0G2JX07_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07", "type": "external" } ], "mass": 42817.0, "length": 370, "protein_name": "Death-associated protein kinase 2", "gene_name": "Dapk2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dapk2", "gene_names_refseq": "", "protein_names_uniprotkb": "Death-associated protein kinase 2; 2.7.11.1; DAP-kinase-related protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031410 cytoplasmic vesicle;GO:0034423 autophagosome lumen;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0043276 anoikis;GO:2001242 regulation of intrinsic apoptotic signaling pathway;GO:2000424 positive regulation of eosinophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JX07-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX20-1", "uniprot_id": [ { "id": "A0A0G2JX20_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX20", "type": "external" } ], "mass": 72593.0, "length": 659, "protein_name": "Katanin p80 WD40 repeat-containing subunit B1", "gene_name": "Katnb1", "organism": "Rat", "refseq_name": "katanin p80 WD40 repeat-containing subunit B1 isoform X1", "refseq_ac": [ { "id": "XP_017456687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017456687", "type": "external" } ], "gene_names_uniprotkb": "Katnb1; KATNB1", "gene_names_refseq": "Katnb1", "protein_names_uniprotkb": "Katanin p80 WD40 repeat-containing subunit B1; Katanin p80 subunit B1; p80 katanin", "protein_names_refseq": "katanin p80 WD40 repeat-containing subunit B1 isoform X1", "tax_id": 10116, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); lissencephaly 6 (Disease Ontology:DOID:0112236); microcephaly (Disease Ontology:DOID:10907)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0046982 protein heterodimerization activity;GO:0070840 dynein complex binding;GO:0060590 ATPase regulator activity", "go_cellular_component": "GO:0008352 katanin complex;GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0007079 mitotic chromosome movement towards spindle pole;GO:0051013 microtubule severing;GO:0031117 positive regulation of microtubule depolymerization;GO:0010976 positive regulation of neuron projection development;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JX20-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX21-1", "uniprot_id": [ { "id": "A0A0G2JX21_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX21", "type": "external" } ], "mass": 66693.0, "length": 585, "protein_name": "Zinc finger protein 131", "gene_name": "Zfp131", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp131", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 131", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:310375); (R-RNO-3899300)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0045111 intermediate filament cytoskeleton", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JX21-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX25-1", "uniprot_id": [ { "id": "A0A0G2JX25_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX25", "type": "external" } ], "mass": 38048.0, "length": 348, "protein_name": "GMP reductase", "gene_name": "Gmpr2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gmpr2", "gene_names_refseq": "", "protein_names_uniprotkb": "GMP reductase; 1.7.1.7", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:192357)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.7.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.7.1.7", "type": "external" } ], "go_molecular_function": "GO:0003920 GMP reductase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:1902560 GMP reductase complex", "go_biological_process": "GO:0046037 GMP metabolic process;GO:0006144 purine nucleobase metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JX25-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX27-1", "uniprot_id": [ { "id": "A0A0G2JX27_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX27", "type": "external" } ], "mass": 76671.0, "length": 700, "protein_name": "Leishmanolysin-like peptidase", "gene_name": "Cirop", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cirop", "gene_names_refseq": "", "protein_names_uniprotkb": "Leishmanolysin-like peptidase; 3.4.24.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "visceral heterotaxy 12 (Disease Ontology:DOID:0051026)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative metalloproteinase that plays a role in left-right patterning process., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JX27-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX30-1", "uniprot_id": [ { "id": "A0A0G2JX30_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX30", "type": "external" } ], "mass": 166085.0, "length": 1469, "protein_name": "ATPase family, AAA domain containing 2B", "gene_name": "Atad2b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Atad2b; 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Moreover, It findings may link AMOT-130 loss and the related spine defects to neurological disorders., [RefSeq, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0043532 angiostatin binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005884 actin filament;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0014069 postsynaptic density", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001525 angiogenesis;GO:0001570 vasculogenesis;GO:0001701 in utero embryonic development;GO:0006935 chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2JX94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXA7-1", "uniprot_id": [ { "id": "A0A0G2JXA7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXA7", "type": "external" } ], "mass": 14567.0, "length": 132, "protein_name": "Ig-like domain-containing protein", "gene_name": "AABR07017868.4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07017868.4", "gene_names_refseq": "", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"hit_score": 0.1, "record_id": "A0A0G2JXA7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXB5-1", "uniprot_id": [ { "id": "A0A0G2JXB5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXB5", "type": "external" } ], "mass": 114089.0, "length": 1002, "protein_name": "Anoctamin", "gene_name": "Ano2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ano2", "gene_names_refseq": "", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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activity;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0097730 non-motile cilium;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0006821 chloride transport;GO:0051649 establishment of localization in cell;GO:1902476 chloride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXB5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXE3-1", "uniprot_id": [ { "id": "A0A0G2JXE3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXE3", "type": "external" } ], "mass": 19069.0, "length": 166, "protein_name": "Uncharacterized protein", "gene_name": "AABR07026557.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07026557.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001669 acrosomal vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXE3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXG2-1", "uniprot_id": [ { "id": "A0A0G2JXG2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2", "type": "external" } ], "mass": 118655.0, "length": 1065, "protein_name": "Lysine-specific demethylase 4B", "gene_name": "Kdm4b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kdm4b", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysine-specific demethylase 4B; 1.14.11.66; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B; [histone H3]-trimethyl-L-lysine(9) demethylase 4B", "protein_names_refseq": "", "tax_id": 10116, "disease": "medulloblastoma (Disease Ontology:DOID:0050902); autosomal dominant intellectual developmental disorder 65 (Disease Ontology:DOID:0061038); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); lung cancer (Disease Ontology:DOID:1324); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); malignant peripheral nerve sheath tumor (Disease Ontology:DOID:5940); colorectal cancer (Disease Ontology:DOID:9256); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (rno:301128); (R-RNO-3214842); (R-RNO-5693565); (R-RNO-9018519)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "1.14.11.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.14.11.69", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.69", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" }, { "id": "1.14.11.79", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.79", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0008270 zinc ion binding;GO:0032452 histone demethylase activity;GO:0032454 histone H3K9 demethylase activity;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0007420 brain development;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXG2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXG7-1", "uniprot_id": [ { "id": "A0A0G2JXG7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXG7", "type": "external" } ], "mass": 151086.0, "length": 1364, "protein_name": "Capping protein regulator and myosin 1 linker 1", "gene_name": "Carmil1", "organism": "Rat", "refseq_name": "F-actin-uncapping protein LRRC16A isoform 4", "refseq_ac": [ { "id": "NP_001178621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178621", "type": "external" } ], "gene_names_uniprotkb": "Carmil1", "gene_names_refseq": "Carmil1; 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tetratricopeptide repeat protein 7B", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXJ6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXK2-1", "uniprot_id": [ { "id": "A0A0G2JXK2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXK2", "type": "external" } ], "mass": 31689.0, "length": 279, "protein_name": "B-cell receptor-associated protein", "gene_name": "Bcap31", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bcap31", "gene_names_refseq": "", "protein_names_uniprotkb": "B-cell receptor-associated protein; BCR-associated protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "deafness, dystonia, and cerebral hypomyelination (Disease Ontology:DOID:0112123); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (R-RNO-111465); (R-RNO-75153); (R-RNO-8980692); (R-RNO-983170)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Plays a role in the export of secreted proteins in the ER., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0042288 MHC class I protein binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006955 immune response;GO:0007283 spermatogenesis;GO:0006626 protein targeting to mitochondrion;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXK2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXL5-1", "uniprot_id": [ { "id": "A0A0G2JXL5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXL5", "type": "external" } ], "mass": 726599.0, "length": 7415, "protein_name": "Mucin 19, oligomeric", "gene_name": "Muc19; Smgc", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Muc19; Smgc; AC096792.1; Smgc", "gene_names_refseq": "", "protein_names_uniprotkb": "Mucin 19, oligomeric", "protein_names_refseq": "", "tax_id": 10116, "disease": "Sjogren's syndrome (Disease Ontology:DOID:12894)", "pathway": " (R-RNO-913709); (R-RNO-977068)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 10, "predicted_n_glycosites": 0, "predicted_o_glycosites": 10, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046848 hydroxyapatite binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0045087 innate immune response;GO:0070098 chemokine-mediated signaling pathway;GO:0030324 lung development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXL5-1", "record_type": "protein", "filter_code": "0000000.1000011.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXL7-1", "uniprot_id": [ { "id": "A0A0G2JXL7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXL7", "type": "external" } ], "mass": 38960.0, "length": 496, "protein_name": "Loricrin cornified envelope precursor protein", "gene_name": "Loricrin", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Loricrin", "gene_names_refseq": "", "protein_names_uniprotkb": "Loricrin cornified envelope precursor protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009898 cytoplasmic side of plasma membrane;GO:0001533 cornified envelope", "go_biological_process": "GO:0030216 keratinocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXL7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXM5-1", "uniprot_id": [ { "id": "A0A0G2JXM5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXM5", "type": "external" } ], "mass": 46322.0, "length": 420, "protein_name": "Polymerase delta-interacting protein 3", "gene_name": "Poldip3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Poldip3", "gene_names_refseq": "", "protein_names_uniprotkb": "Polymerase delta-interacting protein 3; S6K1 Aly/REF-like target", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-159236); (R-RNO-73856)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0044877 protein-containing complex binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005737 cytoplasm", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXN0-1", "uniprot_id": [ { "id": "A0A0G2JXN0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXN0", "type": "external" } ], "mass": 45188.0, "length": 410, "protein_name": "Transcription factor", "gene_name": "Tfdp1", "organism": "Rat", "refseq_name": "transcription factor Dp-1 isoform 1", "refseq_ac": [ { "id": "NP_001423505", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423505", "type": "external" } ], "gene_names_uniprotkb": "Tfdp1; MGC112830", "gene_names_refseq": "Tfdp1", "protein_names_uniprotkb": "Transcription factor", "protein_names_refseq": "transcription factor Dp-1 isoform 1", "tax_id": 10116, "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182)", "pathway": " (R-RNO-1538133); (R-RNO-2173796); (R-RNO-69231); (R-RNO-8953750)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0019904 protein domain specific binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0090575 RNA polymerase II transcription regulator complex;GO:0035189 Rb-E2F complex", "go_biological_process": "GO:2000278 regulation of DNA biosynthetic process;GO:0070345 negative regulation of fat cell proliferation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXN0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXN2-1", "uniprot_id": [ { "id": "TRI46_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXN2", "type": "external" } ], "mass": 83431.0, "length": 759, "protein_name": "Tripartite motif-containing protein 46", "gene_name": "Trim46", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Trim46", "gene_names_refseq": "", "protein_names_uniprotkb": "Tripartite motif-containing protein 46", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "22673903;26671463;38843836", "class_list": "", "function": "Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A096MKD9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0044304 main axon;GO:1904115 axon cytoplasm;GO:0043194 axon initial segment;GO:1990769 proximal neuron projection", "go_biological_process": "GO:0099612 protein localization to axon;GO:0007409 axonogenesis;GO:0001764 neuron migration;GO:0032880 regulation of protein localization;GO:0048490 anterograde synaptic vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JXN2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0100000001001.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXN8-1", "uniprot_id": [ { "id": "A0A0G2JXN8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXN8", "type": "external" } ], "mass": 104050.0, "length": 910, "protein_name": "Oxysterol-binding protein", "gene_name": "Osbpl8", "organism": "Rat", "refseq_name": "oxysterol-binding protein-related protein 8", "refseq_ac": [ { "id": "NP_001296384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296384", "type": "external" } ], "gene_names_uniprotkb": "Osbpl8", "gene_names_refseq": "Osbpl8; RGD1561474", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "oxysterol-binding protein-related protein 8", "tax_id": 10116, "disease": "", "pathway": " (rno:314824); (R-RNO-1482801)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. Binds oxysterol, 25-hydroxycholesterol and cholesterol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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"phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6 isoform 1", "refseq_ac": [ { "id": "NP_001381640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381640", "type": "external" } ], "gene_names_uniprotkb": "Mtmr6", "gene_names_refseq": "Mtmr6", "protein_names_uniprotkb": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6; 3.1.3.95; Myotubularin-related protein 6; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6 isoform 1; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase", "tax_id": 10116, "disease": "centronuclear myopathy X-linked (Disease Ontology:DOID:0111225); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); centronuclear myopathy (Disease Ontology:DOID:14717)", "pathway": " (R-RNO-1660499)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;23188820", "class_list": "", "function": "Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Binds with high affinity to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) but also to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), phosphatidic acid and phosphatidylserine (By similarity). Negatively regulates ER-Golgi protein transport (PubMed:23188820). Probably in association with MTMR9, plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3-phosphate in membrane ruffles. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4(+) T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3-phosphate. Negatively regulates proliferation of reactivated CD4(+) T-cells. In complex with MTMR9, negatively regulates DNA damage-induced apoptosis. The formation of the MTMR6-MTMR9 complex stabilizes both MTMR6 and MTMR9 protein levels (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.64", "type": "external" } ], "go_molecular_function": "GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity;GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm;GO:0032587 ruffle membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0046856 phosphatidylinositol dephosphorylation;GO:0046488 phosphatidylinositol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JXT6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000001.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXT8-1", "uniprot_id": [ { "id": "A0A0G2JXT8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXT8", "type": "external" } ], "mass": 277844.0, "length": 2602, "protein_name": "Filamin B", "gene_name": "Flnb", "organism": "Rat", "refseq_name": "filamin-B isoform 1", "refseq_ac": [ { "id": "NP_001418475", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418475", "type": "external" } ], "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Flnb", "protein_names_uniprotkb": "Filamin B", "protein_names_refseq": "filamin B, beta; filamin, beta; filamin-B isoform 1; filamin-B-like", "tax_id": 10116, "disease": "atelosteogenesis (Disease Ontology:DOID:0050648); Boomerang dysplasia (Disease Ontology:DOID:0050680); spinal disease (Disease Ontology:DOID:0060564); bone development disease (Disease Ontology:DOID:0080006); myofibrillar myopathy 5 (Disease Ontology:DOID:0080096); spondylocarpotarsal synostosis syndrome (Disease Ontology:DOID:0090116); distal myopathy 4 (Disease Ontology:DOID:0111190); clubfoot (Disease Ontology:DOID:11836); Larsen syndrome (Disease Ontology:DOID:14764); osteochondrodysplasia (Disease Ontology:DOID:2256); myopathy (Disease Ontology:DOID:423); cleft palate (Disease Ontology:DOID:674)", "pathway": " (rno:306204); (R-RNO-1169408)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005903 brush border;GO:0005925 focal adhesion;GO:0043025 neuronal cell body;GO:0001725 stress fiber;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0003334 keratinocyte development;GO:0003382 epithelial cell morphogenesis;GO:0071346 cellular response to type II interferon;GO:0007519 skeletal muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXT8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXT9-1", "uniprot_id": [ { "id": "A0A0G2JXT9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXT9", "type": "external" } ], "mass": 222093.0, "length": 2057, "protein_name": "Rho guanine nucleotide exchange factor 17", "gene_name": "Arhgef17", "organism": "Rat", "refseq_name": "rho guanine nucleotide exchange factor 17", "refseq_ac": [ { "id": "NP_001388752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388752", "type": "external" } ], "gene_names_uniprotkb": "Arhgef17", "gene_names_refseq": "Arhgef17", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 17", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 17; rho guanine nucleotide exchange factor 17", "tax_id": 10116, "disease": "intracranial aneurysm (Disease Ontology:DOID:10941)", "pathway": " (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXT9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXU3-1", "uniprot_id": [ { "id": "A0A0G2JXU3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXU3", "type": "external" } ], "mass": 35732.0, "length": 322, "protein_name": "MAGE family member A10", "gene_name": "Magea10", "organism": "Rat", "refseq_name": "melanoma-associated antigen 10", "refseq_ac": [ { "id": "NP_001395765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395765", "type": "external" } ], "gene_names_uniprotkb": "Magea10", "gene_names_refseq": "Magea10; RGD1563693", "protein_names_uniprotkb": "MAGE family member A10", "protein_names_refseq": "melanoma antigen family A, 10; melanoma-associated antigen 10", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXU3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXU5-1", "uniprot_id": [ { "id": "A0A0G2JXU5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXU5", "type": "external" } ], "mass": 53823.0, "length": 495, "protein_name": "Solute carrier family 17, member 4", "gene_name": "Slc17a4", "organism": "Rat", "refseq_name": "probable small intestine urate exporter", "refseq_ac": [ { "id": "NP_001258143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258143", "type": "external" } ], "gene_names_uniprotkb": "Slc17a4", "gene_names_refseq": "Slc17a4", "protein_names_uniprotkb": "Solute carrier family 17, member 4", "protein_names_refseq": "probable small intestine urate exporter; solute carrier family 17 (sodium phosphate), member 4", "tax_id": 10116, "disease": "", "pathway": " (rno:679784)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015293 symporter activity;GO:0015349 thyroid hormone transmembrane transporter activity;GO:0015143 urate transmembrane transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0031526 brush border membrane", "go_biological_process": "GO:0006814 sodium ion transport;GO:0044341 sodium-dependent phosphate transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXU5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXV9-1", "uniprot_id": [ { "id": "A0A0G2JXV9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXV9", "type": "external" } ], "mass": 26503.0, "length": 248, "protein_name": "Paired related homeobox 2", "gene_name": "Prrx2", "organism": "Rat", "refseq_name": "paired mesoderm homeobox protein 2", "refseq_ac": [ { "id": "NP_001402085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402085", "type": "external" } ], "gene_names_uniprotkb": "Prrx2", "gene_names_refseq": "Prrx2; Prx2", "protein_names_uniprotkb": "Paired related homeobox 2", "protein_names_refseq": "paired mesoderm homeobox protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "22577874;23644741;24881871;25795141;39434056", "class_list": "", "function": "Data indicate that PRXs are produced in the pituitary progenitor cells and may play roles in the process of terminal differentiation during early pituitary organogenesis., [RefSeq, PubMed]; Expression stimulated by Klf6, [RefSeq, PubMed]; PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are present at the periphery of the embryonic pituitary and participate in pituitary vasculogenesis by differentiation into vascular endothelial cells and pericytes., [RefSeq, PubMed]; PRX proteins, especially PRX2, play a role in the morphogenesis of the primordial tissues formed by the epithelio-mesenchymal interaction and that neural crest cells contribute to the morphogenesis of tissues derived from the cranial placode., [RefSeq, PubMed]; Upregulation of PRRX2 by silencing Marveld3 as a protective mechanism against radiation-induced ferroptosis in skin cells. 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Ptprj", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase eta; 3.1.3.48; Protein-tyrosine phosphatase receptor type J", "protein_names_refseq": "density enhanced phosphatase-1; receptor-type tyrosine-protein phosphatase eta isoform 1 precursor; receptor-type tyrosine-protein phosphatase eta", "tax_id": 10116, "disease": "hypertension (Disease Ontology:DOID:10763); thrombocytopenia (Disease Ontology:DOID:1588); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung adenocarcinoma (Disease Ontology:DOID:3910); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" } ], "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0019901 protein kinase binding;GO:0051019 mitogen-activated protein kinase binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0009986 cell surface;GO:0016604 nuclear body", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0001570 vasculogenesis;GO:0007507 heart development;GO:0008285 negative regulation of cell population proliferation;GO:0030155 regulation of cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JXZ9-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.0000000000001000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JY13-1", "uniprot_id": [ { "id": "A0A0G2JY13_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JY13", "type": "external" } ], "mass": 7842.0, "length": 69, "protein_name": "A-kinase anchor inhibitor 1", "gene_name": "Akain1", "organism": "Rat", "refseq_name": "A-kinase anchor protein inhibitor 1", "refseq_ac": [ { "id": "NP_001386352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386352", "type": "external" } ], "gene_names_uniprotkb": "Akain1", "gene_names_refseq": "Akain1", "protein_names_uniprotkb": "A-kinase anchor inhibitor 1", "protein_names_refseq": "A kinase (PRKA) anchor inhibitor 1; 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(R-RNO-445095); (R-RNO-5673001); (R-RNO-6807878)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032029 myosin tail binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0030507 spectrin binding;GO:0019894 kinesin binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0097381 photoreceptor disc membrane", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0007030 Golgi organization;GO:0007041 lysosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JY25-1", "record_type": "protein", "filter_code": "0000000.0000001.001000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JY53-1", "uniprot_id": [ { "id": "A0A0G2JY53_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JY53", "type": "external" } ], "mass": 221716.0, "length": 1928, "protein_name": "Myosin, heavy chain 15", "gene_name": "Myh15", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Myh15", "gene_names_refseq": "", "protein_names_uniprotkb": "Myosin, heavy chain 15", "protein_names_refseq": "", "tax_id": 10116, "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Plays an essential role in transcription activation mediated by nuclear receptors. 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"0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYA7-1", "uniprot_id": [ { "id": "A0A0G2JYA7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYA7", "type": "external" } ], "mass": 178323.0, "length": 1608, "protein_name": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1", "gene_name": "Tarbp1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tarbp1", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1; 2.1.1.34; TAR RNA-binding protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in a subset of tRNA. Selectively mediates Gm18 methylation of tRNAGln-TTG/CTG and tRNASer-TGA/GCT. 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"synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYG8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYH9-1", "uniprot_id": [ { "id": "A0A0G2JYH9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYH9", "type": "external" } ], "mass": 176840.0, "length": 1587, "protein_name": "Transport and golgi organization 6 homolog", "gene_name": "Has3; Tango6", "organism": "Rat", "refseq_name": "hyaluronan synthase 3", "refseq_ac": [ { "id": "NP_758822", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_758822", "type": "external" } ], "gene_names_uniprotkb": "Has3; Tango6; RGD1559841; Tango6", "gene_names_refseq": "Has3", "protein_names_uniprotkb": "Transport and golgi organization 6 homolog", "protein_names_refseq": "hyaluronan synthase 3", "tax_id": 10116, "disease": "pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (rno:266805)", 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYI7-1", "uniprot_id": [ { "id": "A0A0G2JYI7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYI7", "type": "external" } ], "mass": 119917.0, "length": 1147, "protein_name": "Ubiquitin-associated protein 2", "gene_name": "Ubap2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ubap2", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin-associated protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "18683930;22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0061484 hematopoietic stem cell homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JYI7-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYJ3-1", "uniprot_id": [ { "id": "A0A0G2JYJ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYJ3", "type": "external" } ], "mass": 35217.0, "length": 311, "protein_name": "Olfactory receptor family 6 subfamily C member 3D", "gene_name": "Or6c3d", "organism": "Rat", "refseq_name": "olfactory receptor Olr894", "refseq_ac": [ { "id": "NP_001000940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000940", "type": "external" } ], "gene_names_uniprotkb": "Or6c3d", "gene_names_refseq": "Olr894; Or6c3d", "protein_names_uniprotkb": "Olfactory receptor family 6 subfamily C member 3D", "protein_names_refseq": "olfactory receptor 894; olfactory receptor Olr894; olfactory receptor gene Olr894", "tax_id": 10116, "disease": "", "pathway": " (rno:405277)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYJ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYJ8-1", "uniprot_id": [ { "id": "A0A0G2JYJ8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYJ8", "type": "external" } ], "mass": 50974.0, "length": 452, "protein_name": "Tetratricopeptide repeat domain 23-like", "gene_name": "Ttc23l", "organism": "Rat", "refseq_name": "tetratricopeptide repeat protein 23-like isoform 1", "refseq_ac": [ { "id": "NP_001420149", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420149", "type": "external" } ], "gene_names_uniprotkb": "Ttc23l", "gene_names_refseq": "RGD1564928; Ttc23l", "protein_names_uniprotkb": "Tetratricopeptide repeat domain 23-like", "protein_names_refseq": "tetratricopeptide repeat protein 23-like isoform 1; tetratricopeptide repeat protein 23-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYJ8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYK5-1", "uniprot_id": [ { "id": "A0A0G2JYK5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYK5", "type": "external" } ], "mass": 32458.0, "length": 295, "protein_name": "Protein boule-like", "gene_name": "Boll", "organism": "Rat", "refseq_name": "protein boule-like isoform 3", "refseq_ac": [ { "id": "NP_001419446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419446", "type": "external" } ], "gene_names_uniprotkb": "Boll; LOC100911373", "gene_names_refseq": "Boll; RGD1559527", "protein_names_uniprotkb": "Protein boule-like", "protein_names_refseq": "bol, boule-like; boule homolog, RNA binding protein; boule-like RNA-binding protein; protein boule-like isoform 3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0008494 translation activator activity;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0051321 meiotic cell cycle;GO:0045948 positive regulation of translational initiation;GO:0070935 3'-UTR-mediated mRNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JYK5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYL5-1", "uniprot_id": [ { "id": "A0A0G2JYL5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYL5", "type": "external" } ], "mass": 517774.0, "length": 4508, "protein_name": "Dynein axonemal heavy chain 2", "gene_name": "Dnah2", "organism": "Rat", "refseq_name": "dynein axonemal heavy chain 2", "refseq_ac": [ { "id": "NP_001094146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094146", "type": "external" } ], "gene_names_uniprotkb": "Dnah2", "gene_names_refseq": "DLP2; Dnah2; Dnahc2; axo f", "protein_names_uniprotkb": "Dynein axonemal heavy chain 2; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2", "protein_names_refseq": "axonemal dynein heavy chain; dynein axonemal heavy chain 2; dynein heavy chain 2, axonemal-like; dynein heavy chain 2, axonemal; dynein-like protein 2", "tax_id": 10116, "disease": "spermatogenic failure 45 (Disease Ontology:DOID:0112163)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the axonemal inner dynein arm complex plays a central role in ciliary beat. Expressed in sperm flagellum, it is required for sperm motility. Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005929 cilium;GO:0031514 motile cilium;GO:0036126 sperm flagellum;GO:0005930 axoneme", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0003341 cilium movement;GO:0036159 inner dynein arm assembly;GO:0060285 cilium-dependent cell motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYL5-1", "record_type": "protein", "filter_code": "0000000.0000010.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYM7-1", "uniprot_id": [ { "id": "A0A0G2JYM7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYM7", "type": "external" } ], "mass": 97752.0, "length": 930, "protein_name": "von Willebrand factor C and EGF domain-containing protein", "gene_name": "Vwce", "organism": "Rat", "refseq_name": "von Willebrand factor C and EGF domain-containing protein precursor", "refseq_ac": [ { "id": "NP_001258240", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258240", "type": "external" } ], "gene_names_uniprotkb": "Vwce", "gene_names_refseq": "RGD1309910; Vwce", "protein_names_uniprotkb": "von Willebrand factor C and EGF domain-containing protein", "protein_names_refseq": "von Willebrand factor C and EGF domain-containing protein precursor; von Willebrand factor C and EGF domain-containing protein", "tax_id": 10116, "disease": "", "pathway": " (rno:309209)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm", "go_biological_process": "GO:0098586 cellular response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYM7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYM8-1", "uniprot_id": [ { "id": "A0A0G2JYM8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYM8", "type": "external" } ], "mass": 68356.0, "length": 589, "protein_name": "Zinc finger protein 386 (Kruppel-like)", "gene_name": "Zfp386", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp386", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 386 (Kruppel-like)", "protein_names_refseq": "", "tax_id": 10116, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515)", "pathway": " (R-RNO-212436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003690 double-stranded DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYM8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYN4-1", "uniprot_id": [ { "id": "A0A0G2JYN4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYN4", "type": "external" } ], "mass": 42479.0, "length": 377, "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "gene_name": "Ergic2", "organism": "Rat", "refseq_name": "endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform 1", "refseq_ac": [ { "id": "NP_001381859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381859", "type": "external" } ], "gene_names_uniprotkb": "Ergic2", "gene_names_refseq": "Ergic2; RGD1310606", "protein_names_uniprotkb": "Endoplasmic reticulum-Golgi intermediate compartment protein", "protein_names_refseq": "endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform 1; endoplasmic reticulum-Golgi intermediate compartment protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in transport between endoplasmic reticulum and Golgi., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYN4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "uniprot_id": [ { "id": "A0A0G2JYP5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYP5", "type": "external" } ], "mass": 35287.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1319", "refseq_ac": [ { "id": "NP_001000470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000470", "type": "external" } ], "gene_names_uniprotkb": "Or8g52b", "gene_names_refseq": "Olr1319; Or8g52b; ratchr8-42701066-42702004_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1319; olfactory receptor Olr1319; olfactory receptor gene Olr1319", "tax_id": 10116, "disease": "", "pathway": " (rno:300620)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYP5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYQ1-1", "uniprot_id": [ { "id": "A0A0G2JYQ1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYQ1", "type": "external" } ], "mass": 44815.0, "length": 407, "protein_name": "HAUS augmin-like complex, subunit 7", "gene_name": "Haus7", "organism": "Rat", "refseq_name": "HAUS augmin-like complex subunit 7 isoform X1", "refseq_ac": [ { "id": "XP_038955450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038955450", "type": "external" } ], "gene_names_uniprotkb": "Haus7; Uchl5ip", "gene_names_refseq": "Haus7; RGD1562991; Uchl5ip", "protein_names_uniprotkb": "HAUS augmin-like complex, subunit 7", "protein_names_refseq": "HAUS augmin-like complex subunit 7 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-8854518)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031996 thioesterase binding;GO:0051011 microtubule minus-end binding", "go_cellular_component": "GO:0005813 centrosome;GO:0070652 HAUS complex;GO:1990498 mitotic spindle microtubule;GO:0005730 nucleolus;GO:0005886 plasma membrane", "go_biological_process": "GO:0007098 centrosome cycle;GO:0051225 spindle assembly;GO:0031023 microtubule organizing center organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JYQ1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYQ2-1", "uniprot_id": [ { "id": "A0A0G2JYQ2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYQ2", "type": "external" } ], "mass": 52445.0, "length": 475, "protein_name": "PBX/knotted 1 homeobox 2", "gene_name": "Pknox2", "organism": "Rat", "refseq_name": "homeobox protein PKNOX2 isoform 1", "refseq_ac": [ { "id": "NP_001258207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258207", "type": "external" } ], "gene_names_uniprotkb": "Pknox2", "gene_names_refseq": "Pknox2", "protein_names_uniprotkb": "PBX/knotted 1 homeobox 2", "protein_names_refseq": "homeobox protein Meis2-like; 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"reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0007015 actin filament organization;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051496 positive regulation of stress fiber assembly;GO:0051492 regulation of stress fiber assembly;GO:0007097 nuclear migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JZ38-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZ48-1", "uniprot_id": [ { "id": "A0A0G2JZ48_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ48", "type": "external" } ], "mass": 121830.0, "length": 1095, "protein_name": "TATA element modulatory factor 1", "gene_name": "Tmf1", "organism": "Rat", "refseq_name": "TATA element modulatory factor", "refseq_ac": [ { "id": "NP_446123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_446123", "type": "external" } ], "gene_names_uniprotkb": "Tmf1", "gene_names_refseq": "Tmf1", "protein_names_uniprotkb": "TATA element modulatory factor 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"total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0050681 nuclear androgen receptor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0032275 luteinizing hormone secretion;GO:1904036 negative regulation of epithelial cell apoptotic process;GO:0010629 negative regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JZ48-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZ53-1", "uniprot_id": [ { "id": "A0A0G2JZ53_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ53", "type": "external" } ], "mass": 539426.0, "length": 4949, "protein_name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "gene_name": "Birc6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Birc6", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6; 2.3.2.24; BIR repeat-containing ubiquitin-conjugating enzyme; Baculoviral IAP repeat-containing protein 6; Ubiquitin-conjugating BIR domain enzyme apollon", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004842 ubiquitin-protein transferase activity;GO:0004869 cysteine-type endopeptidase inhibitor activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005768 endosome;GO:0005813 centrosome;GO:0016020 membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0008284 positive regulation of cell population proliferation;GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JZ53-1", "record_type": "protein", "filter_code": "0000000.0000100.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZ60-1", "uniprot_id": [ { "id": "A0A0G2JZ60_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ60", "type": "external" } ], "mass": 57114.0, "length": 508, "protein_name": "Fibronectin type III and SPRY domain containing 1-like", "gene_name": "Fsd1l", "organism": "Rat", "refseq_name": "fibronectin type III and SPRY domain containing 1-like isoform 1", "refseq_ac": [ { "id": "NP_001418100", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418100", "type": "external" } ], "gene_names_uniprotkb": "Fsd1l", "gene_names_refseq": "Fsd1l; RGD1564809", "protein_names_uniprotkb": "Fibronectin type III and SPRY domain containing 1-like", "protein_names_refseq": "fibronectin type III and SPRY domain containing 1-like isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:313208)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JZ60-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZ70-1", "uniprot_id": [ { "id": "A0A0G2JZ70_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ70", "type": "external" } ], "mass": 23460.0, "length": 213, "protein_name": "Transcription initiation factor TFIID subunit 12", "gene_name": "Taf12", "organism": "Rat", "refseq_name": "transcription initiation factor TFIID subunit 12 isoform 1", "refseq_ac": [ { "id": "XP_006239129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006239129", "type": "external" } ], "gene_names_uniprotkb": "Taf12", "gene_names_refseq": "Taf12", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 12", "protein_names_refseq": "TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor; transcription initiation factor TFIID subunit 12 isoform 1; transcription initiation factor TFIID subunit 12", "tax_id": 10116, "disease": "", "pathway": " (rno:682902); (R-RNO-674695); (R-RNO-6804756); (R-RNO-73776); (R-RNO-73779); (R-RNO-75953); (R-RNO-76042)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the TATA-binding protein-free TAF complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0046982 protein heterodimerization activity;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0042789 mRNA transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JZ70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZ79-1", "uniprot_id": [ { "id": "SIR1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ79", "type": "external" } ], "mass": 62059.0, "length": 555, "protein_name": "NAD-dependent protein deacetylase sirtuin-1", "gene_name": "Sirt1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Sirt1", "gene_names_refseq": "", "protein_names_uniprotkb": "NAD-dependent protein deacetylase sirtuin-1; 2.3.1.-; 2.3.1.286; NAD-dependent protein deacylase sirtuin-1", "protein_names_refseq": "", "tax_id": 10116, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); osteoporosis (Disease Ontology:DOID:11476); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); epilepsy (Disease Ontology:DOID:1826); impotence (Disease Ontology:DOID:1875); atherosclerosis (Disease Ontology:DOID:1936); acute kidney failure (Disease Ontology:DOID:3021); middle cerebral artery infarction (Disease Ontology:DOID:3525); macular degeneration (Disease Ontology:DOID:4448); myocardial infarction (Disease Ontology:DOID:5844); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); senile cataract (Disease Ontology:DOID:9669); obesity (Disease Ontology:DOID:9970); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (R-RNO-3371453); (R-RNO-427359); (R-RNO-9617629); (R-RNO-9764725); (R-RNO-9841922); (R-RNO-9856649)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "38300636", "class_list": "", "function": "NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. Serves as a sensor of the cytosolic ratio of NAD(+)/NADH which is altered by glucose deprivation and metabolic changes associated with caloric restriction. Is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT). Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. Deacetylates 'Lys-266' of SUV39H1, leading to its activation. Inhibits skeletal muscle differentiation by deacetylating PCAF and MYOD1. Deacetylates H2A and 'Lys-26' of H1-4. Deacetylates 'Lys-16' of histone H4 (in vitro). Involved in NR0B2/SHP corepression function through chromatin remodeling: Recruited to LRH1 target gene promoters by NR0B2/SHP thereby stimulating histone H3 and H4 deacetylation leading to transcriptional repression. Proposed to contribute to genomic integrity via positive regulation of telomere length; however, reports on localization to pericentromeric heterochromatin are conflicting. Proposed to play a role in constitutive heterochromatin (CH) formation and/or maintenance through regulation of the available pool of nuclear SUV39H1. Upon oxidative/metabolic stress decreases SUV39H1 degradation by inhibiting SUV39H1 polyubiquitination by MDM2. This increase in SUV39H1 levels enhances SUV39H1 turnover in CH, which in turn seems to accelerate renewal of the heterochromatin which correlates with greater genomic integrity during stress response. Deacetylates 'Lys-382' of p53/TP53 and impairs its ability to induce transcription-dependent proapoptotic program and modulate cell senescence. Deacetylates TAF1B and thereby represses rDNA transcription by the RNA polymerase I. Deacetylates MYC, promotes the association of MYC with MAX and decreases MYC stability leading to compromised transformational capability. Deacetylates FOXO3 in response to oxidative stress thereby increasing its ability to induce cell cycle arrest and resistance to oxidative stress but inhibiting FOXO3-mediated induction of apoptosis transcriptional activity; also leading to FOXO3 ubiquitination and protesomal degradation. Appears to have a similar effect on MLLT7/FOXO4 in regulation of transcriptional activity and apoptosis. Deacetylates DNMT1; thereby impairs DNMT1 methyltransferase-independent transcription repressor activity, modulates DNMT1 cell cycle regulatory function and DNMT1-mediated gene silencing. Deacetylates RELA/NF-kappa-B p65 thereby inhibiting its transactivating potential and augments apoptosis in response to TNF-alpha. Deacetylates HIF1A, KAT5/TIP60, RB1 and HIC1. Deacetylates FOXO1 resulting in its nuclear retention and enhancement of its transcriptional activity leading to increased gluconeogenesis in liver. Inhibits E2F1 transcriptional activity and apoptotic function, possibly by deacetylation. Involved in HES1- and HEY2-mediated transcriptional repression. In cooperation with MYCN seems to be involved in transcriptional repression of DUSP6/MAPK3 leading to MYCN stabilization by phosphorylation at 'Ser-62'. Deacetylates MEF2D. Required for antagonist-mediated transcription suppression of AR-dependent genes which may be linked to local deacetylation of histone H3. Represses HNF1A-mediated transcription. Required for the repression of ESRRG by CREBZF. Deacetylates NR1H3 AND NR1H2 and deacetylation of NR1H3 at 'Lys-434' positively regulates transcription of NR1H3:RXR target genes, promotes NR1H3 proteasomal degradation and results in cholesterol efflux; a promoter clearing mechanism after reach round of transcription is proposed. Involved in lipid metabolism: deacetylates LPIN1, thereby inhibiting diacylglycerol synthesis. Implicated in regulation of adipogenesis and fat mobilization in white adipocytes by repression of PPARG which probably involves association with NCOR1 and SMRT/NCOR2. Deacetylates p300/EP300 and PRMT1. Deacetylates ACSS2 leading to its activation, and HMGCS1 deacetylation. Involved in liver and muscle metabolism. Through deacetylation and activation of PPARGC1A is required to activate fatty acid oxidation in skeletal muscle under low-glucose conditions and is involved in glucose homeostasis. Involved in regulation of PPARA and fatty acid beta-oxidation in liver. Involved in positive regulation of insulin secretion in pancreatic beta cells in response to glucose; the function seems to imply transcriptional repression of UCP2. Proposed to deacetylate IRS2 thereby facilitating its insulin-induced tyrosine phosphorylation. Deacetylates SREBF1 isoform SREBP-1C thereby decreasing its stability and transactivation in lipogenic gene expression. Involved in DNA damage response by repressing genes which are involved in DNA repair, such as XPC and TP73, deacetylating XRCC6/Ku70, and facilitating recruitment of additional factors to sites of damaged DNA, such as SIRT1-deacetylated NBN can recruit ATM to initiate DNA repair and SIRT1-deacetylated XPA interacts with RPA2. Also involved in DNA repair of DNA double-strand breaks by homologous recombination and specifically single-strand annealing independently of XRCC6/Ku70 and NBN. Promotes DNA double-strand breaks by mediating deacetylation of SIRT6. Transcriptional suppression of XPC probably involves an E2F4:RBL2 suppressor complex and protein kinase B (AKT) signaling. Transcriptional suppression of TP73 probably involves E2F4 and PCAF. Deacetylates WRN thereby regulating its helicase and exonuclease activities and regulates WRN nuclear translocation in response to DNA damage. Deacetylates APEX1 at 'Lys-6' and 'Lys-7' and stimulates cellular AP endonuclease activity by promoting the association of APEX1 to XRCC1. Catalyzes deacetylation of ERCC4/XPF, thereby impairing interaction with ERCC1 and nucleotide excision repair (NER). Increases p53/TP53-mediated transcription-independent apoptosis by blocking nuclear translocation of cytoplasmic p53/TP53 and probably redirecting it to mitochondria. Deacetylates XRCC6/Ku70 at 'Lys-539' and 'Lys-542' causing it to sequester BAX away from mitochondria thereby inhibiting stress-induced apoptosis. Is involved in autophagy, presumably by deacetylating ATG5, ATG7 and MAP1LC3B/ATG8. Deacetylates AKT1 which leads to enhanced binding of AKT1 and PDK1 to PIP3 and promotes their activation. Proposed to play role in regulation of STK11/LBK1-dependent AMPK signaling pathways implicated in cellular senescence which seems to involve the regulation of the acetylation status of STK11/LBK1. Can deacetylate STK11/LBK1 and thereby increase its activity, cytoplasmic localization and association with STRAD; however, the relevance of such activity in normal cells is unclear. In endothelial cells is shown to inhibit STK11/LBK1 activity and to promote its degradation. Deacetylates SMAD7 at 'Lys-64' and 'Lys-70' thereby promoting its degradation. Deacetylates CIITA and augments its MHC class II transactivation and contributes to its stability. Deacetylates MECOM/EVI1. Deacetylates PML at 'Lys-487' and this deacetylation promotes PML control of PER2 nuclear localization. During the neurogenic transition, represses selective NOTCH1-target genes through histone deacetylation in a BCL6-dependent manner and leading to neuronal differentiation. Regulates the circadian expression of several core clock genes, including BMAL1, RORC, PER2 and CRY1 and plays a critical role in maintaining a controlled rhythmicity in histone acetylation, thereby contributing to circadian chromatin remodeling. Deacetylates BMAL1 and histones at the circadian gene promoters in order to facilitate repression by inhibitory components of the circadian oscillator. Deacetylates PER2, facilitating its ubiquitination and degradation by the proteasome. Protects cardiomyocytes against palmitate-induced apoptosis. Deacetylates XBP1 isoform 2; deacetylation decreases protein stability of XBP1 isoform 2 and inhibits its transcriptional activity. Deacetylates PCK1 and directs its activity toward phosphoenolpyruvate production promoting gluconeogenesis. Involved in the CCAR2-mediated regulation of PCK1 and NR1D1. Deacetylates CTNB1 at 'Lys-49'. In POMC (pro-opiomelanocortin) neurons, required for leptin-induced activation of PI3K signaling. In addition to protein deacetylase activity, also acts as a protein-lysine deacylase by mediating protein depropionylation and decrotonylation. Mediates depropionylation of Osterix (SP7). Catalyzes decrotonylation of histones; it however does not represent a major histone decrotonylase. Deacetylates SOX9; promoting SOX9 nuclear localization and transactivation activity. Involved in the regulation of centrosome duplication. Deacetylates CENATAC in G1 phase, allowing for SASS6 accumulation on the centrosome and subsequent procentriole assembly (By similarity). Deacetylates NDC80/HEC1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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}, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.-", "type": "external" }, { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" } ], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0051019 mitogen-activated protein kinase binding;GO:0019213 deacetylase activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0000785 chromatin;GO:0005677 chromatin silencing complex", "go_biological_process": "GO:0070857 regulation of bile acid biosynthetic process;GO:0090400 stress-induced premature senescence;GO:0000720 pyrimidine dimer repair by nucleotide-excision repair;GO:0031393 negative 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MO25alpha; MO25", "protein_names_uniprotkb": "Calcium binding protein 39", "protein_names_refseq": "calcium-binding protein 39 isoform 2", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162); pancreatic cancer (Disease Ontology:DOID:1793); transient cerebral ischemia (Disease Ontology:DOID:224); hepatocellular carcinoma (Disease Ontology:DOID:684); hyperthyroidism (Disease Ontology:DOID:7998)", "pathway": " (rno:301574); (R-RNO-380972); (R-RNO-6798695)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15292028;18669938;24811174", "class_list": "", "function": "Cab39 differentially interacts with WNK4 and SPAK/OSR1 to switch the classic two kinase cascade into a signal kinase transduction, [RefSeq, PubMed]; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Endurance training markedly increased skeletal muscle LKB1 and MO25 protein without increasing AMPKK activity., [RefSeq, PubMed]; Examine thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0019900 kinase binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0120283 protein serine/threonine kinase binding", "go_cellular_component": "GO:1902554 serine/threonine protein kinase complex;GO:0005737 cytoplasm;GO:0030018 Z disc;GO:0032991 protein-containing complex", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:1901380 negative regulation of potassium ion transmembrane transport;GO:0007165 signal transduction;GO:0035556 intracellular signal transduction;GO:0014823 response to activity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JZH0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZH3-1", "uniprot_id": [ { "id": "A0A0G2JZH3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZH3", "type": "external" } ], "mass": 110917.0, "length": 1023, "protein_name": "Thrombospondin-3", "gene_name": "Thbs3", "organism": "Rat", "refseq_name": "thrombospondin-3 precursor", "refseq_ac": [ { "id": "NP_001292387", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292387", "type": "external" } ], "gene_names_uniprotkb": "Thbs3", "gene_names_refseq": "Thbs3", "protein_names_uniprotkb": "Thrombospondin-3", "protein_names_refseq": "thrombospondin-3 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:681309)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0005509 calcium ion binding;GO:0001968 fibronectin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0043931 ossification involved in bone maturation;GO:0007155 cell adhesion;GO:0060346 bone trabecula formation;GO:0003417 growth plate cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JZH3-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZH4-1", "uniprot_id": [ { "id": "A0A0G2JZH4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZH4", "type": "external" } ], "mass": 36441.0, "length": 336, "protein_name": "Solute carrier family 35 member A1", "gene_name": "Slc35a1", "organism": "Rat", "refseq_name": "CMP-sialic acid transporter", "refseq_ac": [ { "id": "NP_001101394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101394", "type": "external" } ], "gene_names_uniprotkb": "Slc35a1", "gene_names_refseq": "Slc35a1", "protein_names_uniprotkb": "Solute carrier family 35 member A1", "protein_names_refseq": "CMP-sialic acid transporter; solute carrier family 35 (CMP-sialic acid transporter), member 1; solute carrier family 35 (CMP-sialic acid transporter), member A1", "tax_id": 10116, "disease": "congenital disorder of glycosylation type IIf (Disease Ontology:DOID:0070258)", "pathway": " (R-RNO-4085001); (R-RNO-727802); (R-RNO-9939291)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005456 CMP-N-acetylneuraminate transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane", "go_biological_process": "GO:0006054 N-acetylneuraminate metabolic process;GO:0006055 CMP-N-acetylneuraminate biosynthetic process;GO:0015782 CMP-N-acetylneuraminate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JZH4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZH8-1", "uniprot_id": [ { "id": "A0A0G2JZH8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZH8", "type": "external" } ], "mass": 54241.0, "length": 503, "protein_name": "Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex", "gene_name": "Pdhx", "organism": "Rat", "refseq_name": "pyruvate dehydrogenase protein X component, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_063139776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063139776", "type": "external" } ], "gene_names_uniprotkb": "Pdhx; LOC311254", "gene_names_refseq": "Ac1164; Pdhx", "protein_names_uniprotkb": "Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; 2.3.1.-", "protein_names_refseq": "pyruvate dehydrogenase protein X component, mitochondrial isoform X1", "tax_id": 10116, "disease": "sarcoma (Disease Ontology:DOID:1115); pyruvate decarboxylase deficiency (Disease Ontology:DOID:3649)", "pathway": " (R-RNO-204174); (R-RNO-5362517); (R-RNO-9861559)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "28100784", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, 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"type": "external" }, { "id": "2.7.11.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.2", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "3.1.3.43", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.43", "type": "external" }, { "id": "2.3.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.12", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "1.8.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.4", "type": "external" } ], "go_molecular_function": "GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005759 mitochondrial matrix;GO:0005886 plasma membrane;GO:0045254 pyruvate dehydrogenase complex;GO:0005739 mitochondrion", "go_biological_process": "GO:0006086 pyruvate decarboxylation to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JZH8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZH9-1", "uniprot_id": [ { "id": "A0A0G2JZH9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZH9", "type": "external" } ], "mass": 165689.0, "length": 1486, "protein_name": "Putative ATP-dependent RNA helicase DHX57", "gene_name": "Dhx57", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dhx57", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative ATP-dependent RNA helicase DHX57; 3.6.4.13; DEAH box protein 57", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "Probable ATP-binding RNA helicase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the pro-inflammatory cascade., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0061430 bone trabecula morphogenesis;GO:0071348 cellular response to interleukin-11;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JZZ8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K001-1", "uniprot_id": [ { "id": "A0A0G2K001_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K001", "type": "external" } ], "mass": 161060.0, "length": 1444, "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "Nsd3", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase NSD3 isoform 1", "refseq_ac": [ { "id": "NP_001423720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423720", "type": "external" } ], "gene_names_uniprotkb": "Nsd3; Whsc1l1", "gene_names_refseq": "Nsd3; Whsc1l1", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase NSD3; 2.1.1.370; 2.1.1.371; Nuclear SET domain-containing protein 3", "protein_names_refseq": "Wolf-Hirschhorn syndrome candidate 1-like 1; histone-lysine N-methyltransferase NSD3 isoform 1; histone-lysine N-methyltransferase NSD3", "tax_id": 10116, "disease": "Sotos syndrome 1 (Disease Ontology:DOID:0112103); syndrome (Disease Ontology:DOID:225); myeloid leukemia (Disease Ontology:DOID:8692)", "pathway": " (rno:290831); (R-RNO-3214841)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" }, { "id": "2.1.1.371", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.371", "type": "external" }, { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.85", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0046975 histone H3K36 methyltransferase activity;GO:0046976 histone H3K27 methyltransferase activity;GO:0140537 transcription regulator activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005694 chromosome", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K001-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K002-1", "uniprot_id": [ { "id": "A0A0G2K002_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K002", "type": "external" } ], "mass": 43736.0, "length": 373, "protein_name": "LINE-1 retrotransposable element ORF1 protein", "gene_name": "ENSRNOG00000069224", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000069224", "gene_names_refseq": "", "protein_names_uniprotkb": "LINE-1 retrotransposable element ORF1 protein; LINE retrotransposable element 1; LINE1 retrotransposable element 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0032197 retrotransposition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K002-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K008-1", "uniprot_id": [ { "id": "A0A0G2K008_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K008", "type": "external" } ], "mass": 93827.0, "length": 822, "protein_name": "Zinc finger protein with KRAB and SCAN domains 5", "gene_name": "Zkscan5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zkscan5", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein with KRAB and SCAN domains 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-212436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K008-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K010-1", "uniprot_id": [ { "id": "A0A0G2K010_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K010", "type": "external" } ], "mass": 34811.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or4c115", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or4c115", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K010-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K012-1", "uniprot_id": [ { "id": "A0A0G2K012_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K012", "type": "external" } ], "mass": 58352.0, "length": 524, "protein_name": "UBX domain-containing protein 6", "gene_name": "Ubxn6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ubxn6", "gene_names_refseq": "", "protein_names_uniprotkb": "UBX domain-containing protein 6; UBX domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0016020 membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0016236 macroautophagy;GO:0036503 ERAD pathway;GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K012-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K021-1", "uniprot_id": [ { "id": "A0A0G2K021_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K021", "type": "external" } ], "mass": 6154.0, "length": 54, "protein_name": "Thymosin beta 4, X-linked like 2", "gene_name": "Tmsb4xl2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tmsb4xl2", "gene_names_refseq": "", "protein_names_uniprotkb": "Thymosin beta 4, X-linked like 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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"record_id": "A0A0G2K021-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K031-1", "uniprot_id": [ { "id": "A0A0G2K031_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K031", "type": "external" } ], "mass": 58089.0, "length": 515, "protein_name": "Germ cell-less 1, spermatogenesis associated, pseudogene 1", "gene_name": "Gmcl1-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gmcl1-ps1; RGD1565657", "gene_names_refseq": "", "protein_names_uniprotkb": "Germ cell-less 1, spermatogenesis associated, pseudogene 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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Plays an essential role in maintaining nucleolar integrity in planarian stem cells. Maintains embryonic stem cells proliferation by conventional regulation of ribosome assembly and interaction with OCT4 and POU5F1 complex. Regulates antiviral innate immunity by inhibiting the virus-triggered signaling nuclear translocation of IRF3. Mechanistically, acts by disrupting the interaction between IRF3 and importin IPO5. May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. 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"https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0035613 RNA stem-loop binding;GO:0003724 RNA helicase activity;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:0051607 defense response to virus;GO:0006364 rRNA processing;GO:0032480 negative regulation of type I interferon production;GO:0044830 modulation by host of viral RNA genome replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0E0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0E7-1", "uniprot_id": [ { 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Ubiquitinates BCKDK and targets it for degradation, thereby regulating various metabolic processes. Involved in the positive regulation of neurite branching in hippocampal neurons and the control of neuronal spine number and morphology, through the ubiquitination of PPP3CC., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005739 mitochondrion;GO:0014069 postsynaptic density;GO:0098794 postsynapse", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0150052 regulation of postsynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0E7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0E8-1", "uniprot_id": [ { "id": "A0A0G2K0E8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0E8", "type": "external" } ], "mass": 88509.0, "length": 780, "protein_name": "ADAM metallopeptidase domain 21", "gene_name": "Adam21", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Adam21", "gene_names_refseq": "", "protein_names_uniprotkb": "ADAM metallopeptidase domain 21", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100910087)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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"go_biological_process": "GO:0006508 proteolysis;GO:0008584 male gonad development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0E8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0G3-1", "uniprot_id": [ { "id": "A0A0G2K0G3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0G3", "type": "external" } ], "mass": 56787.0, "length": 506, "protein_name": "thioredoxin-disulfide reductase", "gene_name": "Txnrd3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Txnrd3", "gene_names_refseq": "", "protein_names_uniprotkb": "thioredoxin-disulfide reductase; 1.8.1.9", "protein_names_refseq": "", "tax_id": 10116, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal carcinoma (Disease Ontology:DOID:0080199)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": 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10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.9", "type": "external" }, { "id": "1.11.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.2", "type": "external" } ], "go_molecular_function": "GO:0004791 thioredoxin-disulfide reductase (NADPH) activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0010269 response to selenium ion;GO:0045454 cell redox homeostasis;GO:0001825 blastocyst formation;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0G3-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0G8-1", "uniprot_id": [ { "id": "A0A0G2K0G8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0G8", "type": "external" } ], "mass": 35232.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or5b107", "organism": "Rat", "refseq_name": "olfactory receptor Olr361", "refseq_ac": [ { "id": "NP_001000556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000556", "type": "external" } ], "gene_names_uniprotkb": "Or5b107", "gene_names_refseq": "Olr361; Or5b107; ratchr1-216570414-216571346_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 361; olfactory receptor Olr361; olfactory receptor gene Olr361", "tax_id": 10116, "disease": "", "pathway": " (rno:365413)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0G8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0H3-1", "uniprot_id": [ { "id": "A0A0G2K0H3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0H3", "type": "external" } ], "mass": 180094.0, "length": 1611, "protein_name": "Low-density lipoprotein receptor-related protein", "gene_name": "Lrp6", "organism": "Rat", "refseq_name": "low-density lipoprotein receptor-related protein 6 isoform 2", "refseq_ac": [ { "id": "NP_001388749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388749", "type": "external" } ], "gene_names_uniprotkb": "Lrp6", "gene_names_refseq": "Lrp6", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein", "protein_names_refseq": "low-density lipoprotein receptor-related protein 6 isoform 2; low-density lipoprotein receptor-related protein 6", "tax_id": 10116, "disease": "tooth agenesis (Disease Ontology:DOID:0050591); neural tube defect (Disease Ontology:DOID:0080074); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (R-RNO-3772470); (R-RNO-4641262); (R-RNO-4641263)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "27250245;29864925;30070011;35347917;36913109", "class_list": "", "function": "Changes of LRP6/beta-catenin pathway in adipose tissue of rats with intrauterine growth restriction with catch-up growth., [RefSeq, PubMed]; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalosomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation., [UniProtKB, UniProtKB]; Knockdown of LRP6 inhibited the cell viability by activation of Drp1 in glucose deprived-cardiomyocytes., [RefSeq, PubMed]; LRP6 Bidirectionally Regulates Insulin Sensitivity through Insulin Receptor and S6K Signaling in Rats with CG-IUGR., [RefSeq, PubMed]; LRP6 acts as a scaffold protein in cardiac gap junction assembly and intracellular protein trafficking. Publication Status: Online-Only, [RefSeq, PubMed]; LRP6 regulates alternative pre-mRNA splicing., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0097255 R2TP complex;GO:0031011 Ino80 complex;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000812 Swr1 complex;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000492 box C/D snoRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0H9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0I0-1", "uniprot_id": [ { "id": "A0A0G2K0I0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0I0", "type": "external" } ], "mass": 132911.0, "length": 1154, "protein_name": "Anoctamin", "gene_name": "Ano4", "organism": "Rat", "refseq_name": "anoctamin-4 isoform X1", "refseq_ac": [ { "id": "XP_017450215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017450215", "type": "external" } ], "gene_names_uniprotkb": "Ano4", "gene_names_refseq": "Ano4; Tmem16d", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "anoctamin-4 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:299714); (R-RNO-2672351)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0017128 phospholipid scramblase activity;GO:0046983 protein dimerization activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:1902476 chloride transmembrane 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"total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0045111 intermediate filament cytoskeleton;GO:0045095 keratin filament", "go_biological_process": "GO:0045616 regulation of keratinocyte differentiation;GO:0031424 keratinization;GO:0045109 intermediate filament organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0I4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0I5-1", "uniprot_id": [ { "id": "A0A0G2K0I5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0I5", "type": "external" } ], "mass": 23346.0, "length": 208, "protein_name": "Claudin 34B", "gene_name": "Cldn34b", "organism": "Rat", "refseq_name": "claudin 34B", "refseq_ac": [ { "id": "NP_001395800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395800", "type": "external" } ], "gene_names_uniprotkb": "Cldn34b", "gene_names_refseq": "Cldn34b", "protein_names_uniprotkb": "Claudin 34B", "protein_names_refseq": "claudin 34B; claudin-34; rCG36429-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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membrane;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0007155 cell adhesion;GO:0070830 bicellular tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0I5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0J4-1", "uniprot_id": [ { "id": "A0A0G2K0J4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0J4", "type": "external" } ], "mass": 315297.0, "length": 2798, "protein_name": "Nipped-B protein", "gene_name": "Nipbl", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nipbl", "gene_names_refseq": "", "protein_names_uniprotkb": "Nipped-B protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "Cornelia de Lange syndrome 1 (Disease Ontology:DOID:0080505); Cornelia de Lange syndrome (Disease Ontology:DOID:11725); cancer (Disease Ontology:DOID:162)", "pathway": " (R-RNO-2470946)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with MAU2/SCC4 which mediates the loading of the cohesin complex onto chromatin. Plays a role in cohesin loading at sites of DNA damage. Its recruitment to double-strand breaks (DSBs) sites occurs in a CBX3-, RNF8- and RNF168-dependent manner whereas its recruitment to UV irradiation-induced DNA damage sites occurs in a ATM-, ATR-, RNF8- and RNF168-dependent manner. Along with ZNF609, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0070087 chromo shadow domain binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0032039 integrator complex", "go_biological_process": "GO:0061010 gallbladder development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0J4-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0J7-1", "uniprot_id": [ { "id": "A0A0G2K0J7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0J7", "type": "external" } ], "mass": 113330.0, "length": 1030, "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase", "gene_name": "Ctdp1", "organism": "Rat", "refseq_name": "RNA polymerase II subunit A C-terminal domain phosphatase", "refseq_ac": [ { "id": "XP_006255004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006255004", "type": "external" } ], "gene_names_uniprotkb": "Ctdp1", "gene_names_refseq": "Ctdp1", "protein_names_uniprotkb": "RNA polymerase II subunit A C-terminal domain phosphatase; 3.1.3.16; TFIIF-associating CTD phosphatase", "protein_names_refseq": "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1; RNA polymerase II subunit A C-terminal domain phosphatase", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-112382); (R-RNO-113418); (R-RNO-674695); (R-RNO-6796648); (R-RNO-75955)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation., [UniProtKB, UniProtKB, UniProtKB]; This promotes the activity of RNA polymerase II., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.1.3.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.53", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" } ], "go_molecular_function": "GO:0030957 Tat protein binding;GO:0001096 TFIIF-class transcription factor complex binding;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005819 spindle;GO:0051233 spindle midzone", "go_biological_process": "GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development;GO:0010458 exit from mitosis;GO:0043923 positive regulation by host of viral transcription;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0J7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0K4-1", "uniprot_id": [ { "id": "A0A0G2K0K4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0K4", "type": "external" } ], "mass": 34542.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or8g2", "organism": "Rat", "refseq_name": "olfactory receptor Olr1328", "refseq_ac": [ { "id": "NP_001000599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000599", "type": "external" } ], "gene_names_uniprotkb": "Or8g2", "gene_names_refseq": "Olr1328; Or8g2", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1328; olfactory receptor Olr1328; olfactory receptor gene Olr1328", "tax_id": 10116, "disease": "", "pathway": " (rno:367067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0K4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0L0-1", "uniprot_id": [ { "id": "A0A0G2K0L0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0L0", "type": "external" } ], "mass": 70755.0, "length": 624, "protein_name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "gene_name": "Papss1", "organism": "Rat", "refseq_name": "bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "refseq_ac": [ { "id": "NP_001381988", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381988", "type": "external" } ], "gene_names_uniprotkb": "Papss1", "gene_names_refseq": "Papss1", "protein_names_uniprotkb": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; 2.7.1.25; 2.7.7.4; Sulfurylase kinase 1", "protein_names_refseq": "bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-174362)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.25", "type": "external" }, { "id": "2.7.7.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.4", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0004020 adenylylsulfate kinase activity;GO:0004781 sulfate adenylyltransferase (ATP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0000103 sulfate assimilation;GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0L0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0L2-1", "uniprot_id": [ { "id": "A0A0G2K0L2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0L2", "type": "external" } ], "mass": 33488.0, "length": 303, "protein_name": "Olfactory receptor family 12 subfamily J member 2B", "gene_name": "Or12j2b", "organism": "Rat", "refseq_name": "olfactory receptor Olr298", "refseq_ac": [ { "id": "NP_001000235", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000235", "type": "external" } ], "gene_names_uniprotkb": "Or12j2b", "gene_names_refseq": "Olr298; Or12j2b", "protein_names_uniprotkb": "Olfactory receptor family 12 subfamily J member 2B", "protein_names_refseq": "olfactory receptor 298; olfactory receptor Olr298; olfactory receptor gene Olr298", "tax_id": 10116, "disease": "", "pathway": " (rno:293597)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Possible taste receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0L2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0M0-1", "uniprot_id": [ { "id": "A0A0G2K0M0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0M0", "type": "external" } ], "mass": 42035.0, "length": 378, "protein_name": "Probable thioesterase PNKD", "gene_name": "Pnkd", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pnkd", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable thioesterase PNKD; Myofibrillogenesis regulator 1; Paroxysmal nonkinesiogenic dyskinesia protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "paroxysmal nonkinesigenic dyskinesia 1 (Disease Ontology:DOID:0090049)", "pathway": " (rno:100188944)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "Probable thioesterase that may play a role in cellular detoxification processes; it likely acts on a yet-unknown alpha-hydroxythioester substrate. In vitro, it is able to catalyze the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid at very low rate, though this reaction is not physiologically relevant in vivo., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004416 hydroxyacylglutathione hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione;GO:0032225 regulation of synaptic transmission, dopaminergic;GO:0042053 regulation of dopamine metabolic process;GO:0046929 negative regulation of neurotransmitter secretion;GO:0050884 neuromuscular process controlling posture", "synthesized_glycan_count": 0, "hit_score": 0.4, 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"22673903", "class_list": "", "function": "GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0T8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0U0-1", "uniprot_id": [ { "id": "A0A0G2K0U0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0U0", "type": "external" } ], "mass": 97147.0, "length": 836, "protein_name": "Cilia and flagella associated protein 221", "gene_name": "Cfap221", "organism": "Rat", "refseq_name": "cilia and flagella associated protein 221", "refseq_ac": [ { "id": "NP_001416544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001416544", "type": "external" } ], "gene_names_uniprotkb": "Cfap221", "gene_names_refseq": "Cfap221; Pcdp1", "protein_names_uniprotkb": "Cilia and flagella associated protein 221", "protein_names_refseq": "cilia and flagella associated protein 221; primary ciliary dyskinesia protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0U8-1", "uniprot_id": [ { "id": "A0A0G2K0U8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0U8", "type": "external" } ], "mass": 60032.0, "length": 528, "protein_name": "tRNA pseudouridine(55) synthase", "gene_name": "Pus10", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pus10", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA pseudouridine(55) synthase; 5.4.99.25; Coiled-coil domain-containing protein 139", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein with different functions depending on its subcellular location: involved in miRNA processing in the nucleus and acts as a tRNA pseudouridylate synthase in the cytoplasm. In the cytoplasm, acts as a pseudouridylate synthase by catalyzing synthesis of pseudouridine(54) and pseudouridine(55) from uracil-54 and uracil-55, respectively, in the psi GC loop of a subset of tRNAs. tRNA pseudouridylate synthase activity is enhanced by the presence of 1-methyladenosine at position 53-61 of tRNAs. Does not show tRNA pseudouridylate synthase activity in the nucleus. In the nucleus, promotes primary microRNAs (pri-miRNAs) processing independently of its RNA pseudouridylate synthase activity. Binds pri-miRNAs. Modulator of TRAIL/TNFSF10-induced cell death via activation of procaspase-8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009982 pseudouridine synthase activity;GO:0070878 primary miRNA binding;GO:0106029 tRNA pseudouridine synthase activity;GO:0160148 tRNA pseudouridine(55) synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031119 tRNA pseudouridine synthesis;GO:0031053 primary miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0U8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0V6-1", "uniprot_id": [ { "id": "A0A0G2K0V6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0V6", "type": "external" } ], "mass": 68958.0, "length": 640, "protein_name": "E2F transcription factor 3", "gene_name": "E2f3", "organism": "Rat", "refseq_name": "transcription factor E2F3", "refseq_ac": [ { "id": "NP_001131098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001131098", "type": "external" } ], "gene_names_uniprotkb": "E2f3", "gene_names_refseq": "E2f3; RGD1561600", "protein_names_uniprotkb": "E2F transcription factor 3", "protein_names_refseq": "transcription factor E2F3", "tax_id": 10116, "disease": "prostate cancer (Disease Ontology:DOID:10283); high grade glioma (Disease Ontology:DOID:3070); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": " (R-RNO-68911); (R-RNO-69231)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15158336;33058540;34666672;35616132", "class_list": "", "function": "2-Acetylaminofluorene could possibly block G1/S-transition smf slter lelvels of E2f3., [RefSeq, PubMed]; Critical functions of microRNA-30a-5p-E2F3 in cardiomyocyte apoptosis induced by hypoxia/reoxygenation., [RefSeq, PubMed]; Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3. Publication Status: Online-Only, [RefSeq, PubMed]; MicroRNA141 inhibits the differentiation of bone marrowderived mesenchymal stem cells in steroidinduced osteonecrosis via E2F3., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K0V6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0V7-1", "uniprot_id": [ { "id": "A0A0G2K0V7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0V7", "type": "external" } ], "mass": 51359.0, "length": 463, "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "organism": "Rat", "refseq_name": "radial spoke head 14 homolog isoform 2", "refseq_ac": [ { "id": "NP_001388438", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388438", "type": "external" } ], "gene_names_uniprotkb": "Rsph14; Rtdr1", "gene_names_refseq": "Rsph14; Rtdr1", "protein_names_uniprotkb": "Radial spoke head 14 homolog", "protein_names_refseq": "radial spoke head 14 homolog isoform 2; rhabdoid tumor deletion region gene 1; rhabdoid tumor deletion region protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"refseq_ac": [ { "id": "XP_008767191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008767191", "type": "external" } ], "gene_names_uniprotkb": "Ttyh3", "gene_names_refseq": "Ttyh3", "protein_names_uniprotkb": "Protein tweety homolog", "protein_names_refseq": "protein tweety homolog 3 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "Probable chloride channel., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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], "gene_names_uniprotkb": "Tafazzin; TAZ", "gene_names_refseq": "Tafazzin; Taz", "protein_names_uniprotkb": "Tafazzin family protein", "protein_names_refseq": "tafazzin isoform X1", "tax_id": 10116, "disease": "Barth syndrome (Disease Ontology:DOID:0050476); visceral heterotaxy (Disease Ontology:DOID:0050545); cardiomyopathy (Disease Ontology:DOID:0050700); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (R-RNO-1482798)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. 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"0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0Y0-1", "uniprot_id": [ { "id": "A0A0G2K0Y0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0Y0", "type": "external" } ], "mass": 105449.0, "length": 980, "protein_name": "BicC family RNA binding protein 1", "gene_name": "Bicc1", "organism": "Rat", "refseq_name": "protein bicaudal C homolog 1 isoform X2", "refseq_ac": [ { "id": "XP_038954759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038954759", "type": "external" } ], "gene_names_uniprotkb": "Bicc1", "gene_names_refseq": "Bicc1", "protein_names_uniprotkb": "BicC family RNA binding protein 1", "protein_names_refseq": "protein bicaudal C homolog 1 isoform X2", "tax_id": 10116, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); diffuse cystic renal dysplasia (Disease Ontology:DOID:0111682); cystic kidney 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