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Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. 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This record is derived from a genomic sequence (NW_003618265.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061INU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061INU3-1", "uniprot_id": [ { "id": "A0A061INU3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061INU3", "type": "external" } ], "mass": 37307.0, "length": 337, "protein_name": "Transmembrane protein 59-like; Uncharacterized protein family, TMEM59 containing protein", "gene_name": "LOC113833390", "organism": "Hamster", "refseq_name": "transmembrane protein 59-like", "refseq_ac": [ { "id": "XP_027250503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250503", "type": "external" } ], "gene_names_uniprotkb": "LOC113833390; H671_1g1147", "gene_names_refseq": "LOC113833390", "protein_names_uniprotkb": "Transmembrane protein 59-like; Uncharacterized protein family, TMEM59 containing protein", "protein_names_refseq": "transmembrane protein 59-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113833390)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0001658 branching involved in ureteric bud morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061INU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061INU4-1", "uniprot_id": [ { "id": "A0A061INU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061INU4", "type": "external" } ], "mass": 15884.0, "length": 141, "protein_name": "Small ribosomal subunit protein bS18m", "gene_name": "Mrps18c", "organism": "Hamster", "refseq_name": "28S ribosomal protein S18c, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003515911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515911", "type": "external" } ], "gene_names_uniprotkb": "Mrps18c; H671_1g3206", "gene_names_refseq": "Mrps18c", "protein_names_uniprotkb": "Small ribosomal subunit protein bS18m; 28S ribosomal protein S18-1, mitochondrial; 28S ribosomal protein S18c, mitochondrial", "protein_names_refseq": "28S ribosomal protein S18c, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769266)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003621021.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003615246.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be required for pre-mRNA splicing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005681 spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061INW6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061INW8-1", "uniprot_id": [ { "id": "A0A061INW8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061INW8", "type": "external" } ], "mass": 21256.0, "length": 189, "protein_name": "small monomeric GTPase", "gene_name": "Nras", "organism": "Hamster", "refseq_name": "GTPase NRas", "refseq_ac": [ { "id": "XP_003505855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505855", "type": "external" } ], "gene_names_uniprotkb": "Nras; H671_1g3183", "gene_names_refseq": "Nras", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "GTPase NRas", "tax_id": 10029, "disease": "", "pathway": " (cge:100757614)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614192.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Important for the epidermal barrier integrity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0001533 cornified envelope;GO:0030057 desmosome", "go_biological_process": "GO:1990000 amyloid fibril formation;GO:0098609 cell-cell adhesion;GO:0003336 corneocyte desquamation;GO:0043589 skin morphogenesis;GO:1905716 negative regulation of cornification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061INX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061INZ6-1", "uniprot_id": [ { "id": "A0A061INZ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061INZ6", "type": "external" } ], "mass": 154606.0, "length": 1393, "protein_name": "Adhesion G protein-coupled receptor F5", "gene_name": "Adgrf5", "organism": "Hamster", "refseq_name": "adhesion G protein-coupled receptor F5", "refseq_ac": [ { "id": "XP_027243258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243258", "type": "external" } ], "gene_names_uniprotkb": "Adgrf5; H671_1g2440", "gene_names_refseq": "Adgrf5", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor F5; G-protein coupled hepta-helical receptor Ig-hepta; G-protein coupled receptor 116", "protein_names_refseq": "adhesion G protein-coupled receptor F5", "tax_id": 10029, "disease": "", "pathway": " (cge:100769211)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adhesion G protein-coupled receptor. In alveolar type II (ATII or AT2) cells, required for normal lung surfactant homeostasis. Modulation of both surfactant secretion and uptake by ATII cells is mediated by the downstream activation of GNAQ/GNA11 proteins and may be a consequence of increased cortical F-actin assembly induced by ADGRF5 activation. In the kidney, may play a role in the regulation of acid excretion into the primary urine, possibly by regulating the surface expression of V-ATPase proton pump. As a receptor for soluble FNDC4 (sFNDC4), required for proper systemic glucose tolerance, specifically sensitizing white adipose tissue to insulin. 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007603 phototransduction, visible light;GO:0050908 detection of light stimulus involved in visual perception;GO:0050913 sensory perception of bitter taste;GO:0050916 sensory perception of sweet taste", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IP13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IP22-1", "uniprot_id": [ { "id": "A0A061IP22_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IP22", "type": "external" } ], "mass": 93556.0, "length": 821, "protein_name": "Anaphase-promoting complex subunit 4", "gene_name": "Anapc4", "organism": "Hamster", "refseq_name": "anaphase-promoting complex subunit 4 isoform X1", "refseq_ac": [ { "id": "XP_007649950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649950", "type": "external" } ], "gene_names_uniprotkb": "Anapc4; H671_1g1035", "gene_names_refseq": "Anapc4", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 4; Cyclosome subunit 4", "protein_names_refseq": "anaphase-promoting complex subunit 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767504)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615062.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005680 anaphase-promoting complex;GO:0034399 nuclear periphery", "go_biological_process": "GO:0051301 cell division;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0070979 protein K11-linked ubiquitination;GO:0030071 regulation of mitotic metaphase/anaphase transition;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IP22-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IP87-1", "uniprot_id": [ { "id": "A0A061IP87_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IP87", "type": "external" } ], "mass": 32243.0, "length": 309, "protein_name": "Solute carrier family 39 (zinc transporter), member 2; Zinc transporter ZIP2 isoform X1; Zinc transporter ZIP2-like protein", "gene_name": "Slc39a2", "organism": "Hamster", "refseq_name": "zinc transporter ZIP2 isoform X1", "refseq_ac": [ { "id": "XP_003514665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514665", "type": "external" } ], "gene_names_uniprotkb": "Slc39a2; H671_1g2245", "gene_names_refseq": "Slc39a2", "protein_names_uniprotkb": "Solute carrier family 39 (zinc transporter), member 2; Zinc transporter ZIP2 isoform X1; Zinc transporter ZIP2-like protein", "protein_names_refseq": "zinc transporter ZIP2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752281)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616775.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0046873 metal ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0016020 membrane", "go_biological_process": "GO:0030216 keratinocyte differentiation;GO:0070574 cadmium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IP87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IP97-1", "uniprot_id": [ { "id": "A0A061IP97_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IP97", "type": "external" } ], "mass": 36899.0, "length": 322, "protein_name": "Epiphycan", "gene_name": "Epyc", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Epyc; 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H671_1g2238", "gene_names_refseq": "", "protein_names_uniprotkb": "40S ribosomal protein S11", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100763967)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IP99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPA8-1", "uniprot_id": [ { "id": "A0A061IPA8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPA8", "type": "external" } ], "mass": 7891.0, "length": 74, "protein_name": "Mitochondrial import receptor subunit TOM6 homolog; 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614620.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003614628.1) annotated using gene prediction method: Gnomon. 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H671_1g1654", "gene_names_refseq": "F2rl3", "protein_names_uniprotkb": "Proteinase-activated receptor 4; Coagulation factor II receptor-like 3; Thrombin receptor-like 3", "protein_names_refseq": "proteinase-activated receptor 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100757293)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0002020 protease binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0051281 positive regulation of release of sequestered calcium ion into cytosol;GO:0035025 positive regulation of Rho protein signal transduction;GO:0070527 platelet aggregation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPI5-1", "uniprot_id": [ { "id": "A0A061IPI5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPI5", "type": "external" } ], "mass": 56605.0, "length": 495, "protein_name": "Bile acid-sensitive ion channel", "gene_name": "Asic5", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Asic5; H671_1g1629", "gene_names_refseq": "", "protein_names_uniprotkb": "Bile acid-sensitive ion channel; Acid-sensing ion channel subunit family member 5; Amiloride-sensitive cation channel 5; Brain-liver-intestine amiloride-sensitive Na(+) channel", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100768408)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Forms bile acid-gated sodium channels and may play a role in bile acid-dependent absorption and secretion by epithelial cells of the bile ducts. Displays high selectivity for sodium ions but can also permit the permeation of other cations. The gating could be indirect and the consequence of alterations of the membrane environment of the channel by bile acids. As a sodium channel of type II unipolar brush cells of the vestibulocerebellum, controlling the electrical activity of these cells, could play a role in motor coordination and balance., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015280 ligand-gated sodium channel activity;GO:0015252 proton channel activity;GO:0160228 bile acid-gated sodium channel activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0019228 neuronal action potential", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPJ2-1", "uniprot_id": [ { "id": "A0A061IPJ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPJ2", "type": "external" } ], "mass": 94620.0, "length": 824, "protein_name": "AMP deaminase", "gene_name": "Ampd2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ampd2; H671_1g2856; I79_019384", "gene_names_refseq": "", "protein_names_uniprotkb": "AMP deaminase; 3.5.4.6", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100774910)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21804562;23929341;29704459;32410221", "class_list": "", "function": "AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003876 AMP deaminase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046033 AMP metabolic process;GO:0097009 energy homeostasis;GO:0032264 IMP salvage;GO:0042632 cholesterol homeostasis;GO:0052652 cyclic purine nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A061IPJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPK1-1", "uniprot_id": [ { "id": "A0A061IPK1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPK1", "type": "external" } ], "mass": 17620.0, "length": 157, "protein_name": "Ribonuclease pancreatic", "gene_name": "Ear7", "organism": "Hamster", "refseq_name": "eosinophil-associated, ribonuclease A family, member 7 precursor", "refseq_ac": [ { "id": "NP_001231447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231447", "type": "external" } ], "gene_names_uniprotkb": "Ear7; H671_1g1977", "gene_names_refseq": "Ear7", "protein_names_uniprotkb": "Ribonuclease pancreatic; RNase 1; RNase A", "protein_names_refseq": "eosinophil-associated ribonuclease 7; eosinophil-associated, ribonuclease A family, member 7 precursor", "tax_id": 10029, "disease": "", "pathway": " (cge:100689291)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10758160;23929341;29704459;32410221", "class_list": "", "function": "Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA., [UniProtKB, UniProtKB]; VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AFTD01135824.1. On Mar 29, 2018 this sequence version replaced NP_001231447.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004522 ribonuclease A activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006935 chemotaxis;GO:0050830 defense response to Gram-positive bacterium;GO:0002227 innate immune response in mucosa", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A061IPK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPK2-1", "uniprot_id": [ { "id": "A0A061IPK2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPK2", "type": "external" } ], "mass": 55222.0, "length": 505, "protein_name": "RNA-splicing ligase RtcB homolog", "gene_name": "Rtcb", "organism": "Hamster", "refseq_name": "RNA-splicing ligase RtcB homolog isoform X1", "refseq_ac": [ { "id": "XP_007641922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641922", "type": "external" } ], "gene_names_uniprotkb": "Rtcb; H671_1g2846; RTCB", "gene_names_refseq": "Rtcb", "protein_names_uniprotkb": "RNA-splicing ligase RtcB homolog; 3'-phosphate/5'-hydroxy nucleic acid ligase; 6.5.1.8", "protein_names_refseq": "RNA-splicing ligase RtcB homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753929)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 145 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613942.1) and transcript sequence (IACG01093599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.5.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.8", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003972 RNA ligase (ATP) activity;GO:0170057 RNA ligase (GTP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0072669 tRNA-splicing ligase complex", "go_biological_process": "GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPK3-1", "uniprot_id": [ { "id": "A0A061IPK3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPK3", "type": "external" } ], "mass": 61333.0, "length": 538, "protein_name": "Lysosomal cobalamin transport escort protein LMBD1", "gene_name": "Lmbrd1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lmbrd1; H671_1g1587", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysosomal cobalamin transport escort protein LMBD1; LMBR1 domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100753381)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0035612 AP-2 adaptor complex binding;GO:0031419 cobalamin binding;GO:0032050 clathrin heavy chain binding;GO:0140318 protein transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0045334 clathrin-coated endocytic vesicle", "go_biological_process": "GO:0072583 clathrin-dependent endocytosis;GO:0007369 gastrulation;GO:0038016 insulin receptor internalization;GO:0061462 protein localization to lysosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPM3-1", "uniprot_id": [ { "id": "A0A061IPM3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPM3", "type": "external" } ], "mass": 26411.0, "length": 241, "protein_name": "Proteasome subunit alpha type", "gene_name": "Psma5", "organism": "Hamster", "refseq_name": "proteasome subunit alpha type-5", "refseq_ac": [ { "id": "XP_003511013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511013", "type": "external" } ], "gene_names_uniprotkb": "Psma5; H671_1g1958", "gene_names_refseq": "Psma5", "protein_names_uniprotkb": "Proteasome subunit alpha type", "protein_names_refseq": "proteasome subunit alpha type-5", "tax_id": 10029, "disease": "", "pathway": " (cge:100774039)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614997.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPM6-1", "uniprot_id": [ { "id": "A0A061IPM6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPM6", "type": "external" } ], "mass": 45503.0, "length": 400, "protein_name": "Decapping nuclease", "gene_name": "Dxo", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dxo; H671_1g2770", "gene_names_refseq": "", "protein_names_uniprotkb": "Decapping nuclease; 3.6.1.-", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100768556)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0034353 mRNA 5'-diphosphatase activity;GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0004518 nuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0110155 NAD-cap decapping", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPN5-1", "uniprot_id": [ { "id": "A0A061IPN5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPN5", "type": "external" } ], "mass": 25290.0, "length": 226, "protein_name": "14-3-3 protein sigma isoform X2; 14-3-3 protein sigma-like protein", "gene_name": "LOC100754138", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100754138; H671_1g1572", "gene_names_refseq": "", "protein_names_uniprotkb": "14-3-3 protein sigma isoform X2; 14-3-3 protein sigma-like protein", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100754138)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPN5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPQ3-1", "uniprot_id": [ { "id": "A0A061IPQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPQ3", "type": "external" } ], "mass": 30705.0, "length": 274, "protein_name": "Protein canopy homolog 3", "gene_name": "Cnpy3", "organism": "Hamster", "refseq_name": "protein canopy homolog 3", "refseq_ac": [ { "id": "XP_003506101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506101", "type": "external" } ], "gene_names_uniprotkb": "Cnpy3; H671_1g1508", "gene_names_refseq": "Cnpy3", "protein_names_uniprotkb": "Protein canopy homolog 3", "protein_names_refseq": "protein canopy homolog 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100769298)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614206.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003506101.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPR2-1", "uniprot_id": [ { "id": "A0A061IPR2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPR2", "type": "external" } ], "mass": 110653.0, "length": 942, "protein_name": "Coiled-coil domain-containing protein 39", "gene_name": "Ccdc39", "organism": "Hamster", "refseq_name": "coiled-coil domain-containing protein 39", "refseq_ac": [ { "id": "XP_003506800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506800", "type": "external" } ], "gene_names_uniprotkb": "Ccdc39; H671_1g2698", "gene_names_refseq": "Ccdc39", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 39", "protein_names_refseq": "coiled-coil domain-containing protein 39", "tax_id": 10029, "disease": "", "pathway": " (cge:100750499)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614281.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005930 axoneme", "go_biological_process": "GO:0036159 inner dynein arm assembly;GO:0060285 cilium-dependent cell motility;GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPR2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPR5-1", "uniprot_id": [ { "id": "A0A061IPR5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPR5", "type": "external" } ], "mass": 61271.0, "length": 534, "protein_name": "UDP-glucuronosyltransferase", "gene_name": "LOC100762673", "organism": "Hamster", "refseq_name": "UDP-glucuronosyltransferase 2A3", "refseq_ac": [ { "id": "XP_003512337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512337", "type": "external" } ], "gene_names_uniprotkb": "LOC100762673; H671_1g2688", "gene_names_refseq": "LOC100762673", "protein_names_uniprotkb": "UDP-glucuronosyltransferase; 2.4.1.17", "protein_names_refseq": "UDP-glucuronosyltransferase 2A3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762673)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615412.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.17", "type": "external" } ], "go_molecular_function": "GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPR5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPR6-1", "uniprot_id": [ { "id": "A0A061IPR6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPR6", "type": "external" } ], "mass": 22406.0, "length": 204, "protein_name": "Cysteine-rich protein 3", "gene_name": "Crip3", "organism": "Hamster", "refseq_name": "cysteine-rich protein 3 isoform X1", "refseq_ac": [ { "id": "XP_003508369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508369", "type": "external" } ], "gene_names_uniprotkb": "Crip3; H671_1g1522", "gene_names_refseq": "Crip3", "protein_names_uniprotkb": "Cysteine-rich protein 3", "protein_names_refseq": "cysteine-rich protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754142)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614523.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IPR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPS7-1", "uniprot_id": [ { "id": "A0A061IPS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPS7", "type": "external" } ], "mass": 35389.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "LOC100760332", "organism": "Hamster", "refseq_name": "olfactory receptor 11A1", "refseq_ac": [ { "id": "XP_003510701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510701", "type": "external" } ], "gene_names_uniprotkb": "LOC100760332; H671_1g2677", "gene_names_refseq": "LOC100760332", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 11A1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760332)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614926.1) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0000785 chromatin;GO:0090571 RNA polymerase II transcription repressor complex", "go_biological_process": "GO:0001708 cell fate specification;GO:0045893 positive regulation of DNA-templated transcription;GO:0048701 embryonic cranial skeleton morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ17-1", "uniprot_id": [ { "id": "A0A061IQ17_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ17", "type": "external" } ], "mass": 52476.0, "length": 495, "protein_name": "Ankyrin repeat domain 34A; Ankyrin repeat domain-containing protein 34A", "gene_name": "Ankrd34a", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ankrd34a; H671_1g1351", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat domain 34A; Ankyrin repeat domain-containing protein 34A", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100755248)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ35-1", "uniprot_id": [ { "id": "A0A061IQ35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ35", "type": "external" } ], "mass": 56595.0, "length": 511, "protein_name": "Vacuolar proton pump subunit B", "gene_name": "Atp6v1b2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Atp6v1b2; H671_1g2495", "gene_names_refseq": "", "protein_names_uniprotkb": "Vacuolar proton pump subunit B; V-ATPase subunit B; Vacuolar proton pump subunit B", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100774665)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005829 cytosol;GO:0016324 apical plasma membrane;GO:0042470 melanosome;GO:0030665 clathrin-coated vesicle membrane;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0046034 ATP metabolic process;GO:0097401 synaptic vesicle lumen acidification;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ45-1", "uniprot_id": [ { "id": "A0A061IQ45_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ45", "type": "external" } ], "mass": 22357.0, "length": 198, "protein_name": "Synaptobrevin homolog YKT6", "gene_name": "Ykt6", "organism": "Hamster", "refseq_name": "synaptobrevin homolog YKT6", "refseq_ac": [ { "id": "XP_003504801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504801", "type": "external" } ], "gene_names_uniprotkb": "Ykt6; H671_1g1699", "gene_names_refseq": "Ykt6", "protein_names_uniprotkb": "Synaptobrevin homolog YKT6", "protein_names_refseq": "synaptobrevin homolog YKT6", "tax_id": 10029, "disease": "", "pathway": " (cge:100763402)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614085.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005484 SNAP receptor activity;GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005739 mitochondrion;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0006903 vesicle targeting;GO:0006904 vesicle docking involved in exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ50-1", "uniprot_id": [ { "id": "A0A061IQ50_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ50", "type": "external" } ], "mass": 49590.0, "length": 433, "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "LOC100771812", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100771812; H671_1g1312", "gene_names_refseq": "", "protein_names_uniprotkb": "Pyroglutamylated RF-amide peptide receptor; AQ27; G-protein coupled receptor 103; Orexigenic neuropeptide QRFP receptor; SP9155", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100771812)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004983 neuropeptide Y receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ50-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ68-1", "uniprot_id": [ { "id": "A0A061IQ68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ68", "type": "external" } ], "mass": 32779.0, "length": 284, "protein_name": "Tropomyosin alpha-1 chain-like protein; Tropomyosin alpha-4 chain isoform X1", "gene_name": "Tpm4", "organism": "Hamster", "refseq_name": "tropomyosin alpha-4 chain isoform X1", "refseq_ac": [ { "id": "XP_003499135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499135", "type": "external" } ], "gene_names_uniprotkb": "Tpm4; H671_1g1638", "gene_names_refseq": "Tpm4", "protein_names_uniprotkb": "Tropomyosin alpha-1 chain-like protein; Tropomyosin alpha-4 chain isoform X1", "protein_names_refseq": "tropomyosin alpha-4 chain isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761146)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003499135.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ69-1", "uniprot_id": [ { "id": "A0A061IQ69_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ69", "type": "external" } ], "mass": 238052.0, "length": 2128, "protein_name": "Tudor domain-containing protein 6", "gene_name": "Tdrd6", "organism": "Hamster", "refseq_name": "tudor domain-containing protein 6 isoform X2", "refseq_ac": [ { "id": "XP_027243183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243183", "type": "external" } ], "gene_names_uniprotkb": "Tdrd6; H671_1g2437", "gene_names_refseq": "Tdrd6", "protein_names_uniprotkb": "Tudor domain-containing protein 6", "protein_names_refseq": "tudor domain-containing protein 6 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759643)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (during oogenesis), germ plasm (upon fertilization), and for proper miRNA expression and spliceosome maturation. Essential for RNA-dependent helicase UPF1 localization to chromatoid body, for UPF1-UPF2 and UPF1-DDX4 interactions which are required for mRNA degradation, using the extended 3' UTR-triggered nonsense-mediated mRNA decay (NMD) pathway. Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through interaction with arginine N-methyltransferase PRMT5 and symmetrically arginine dimethylated SNRPB (small nuclear ribonucleoprotein-associated protein)., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ69-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ70-1", "uniprot_id": [ { "id": "A0A061IQ70_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ70", "type": "external" } ], "mass": 59947.0, "length": 526, "protein_name": "Vang-like protein", "gene_name": "Vangl1", "organism": "Hamster", "refseq_name": "vang-like protein 1", "refseq_ac": [ { "id": "XP_027249612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249612", "type": "external" } ], "gene_names_uniprotkb": "Vangl1; H671_1g1288", "gene_names_refseq": "Vangl1", "protein_names_uniprotkb": "Vang-like protein", "protein_names_refseq": "vang-like protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750491)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0043473 pigmentation;GO:0120197 mucociliary clearance", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ83-1", "uniprot_id": [ { "id": "A0A061IQ83_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ83", "type": "external" } ], "mass": 73481.0, "length": 659, "protein_name": "Translation factor Guf1", "gene_name": "Guf1", "organism": "Hamster", "refseq_name": "translation factor GUF1, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027246630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246630", "type": "external" } ], "gene_names_uniprotkb": "Guf1; H671_1g2430", "gene_names_refseq": "Guf1", "protein_names_uniprotkb": "Translation factor Guf1", "protein_names_refseq": "translation factor GUF1, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756221)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0097177 mitochondrial ribosome binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006412 translation;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ83-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ90-1", "uniprot_id": [ { "id": "A0A061IQ90_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ90", "type": "external" } ], "mass": 58983.0, "length": 528, "protein_name": "Synaptotagmin-6 isoform X1; Synaptotagmin-6-like protein", "gene_name": "Syt6", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Syt6; H671_1g1207", "gene_names_refseq": "", "protein_names_uniprotkb": "Synaptotagmin-6 isoform X1; Synaptotagmin-6-like protein", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100762050)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0030276 clathrin binding;GO:0000149 SNARE binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030658 transport vesicle membrane;GO:0070382 exocytic vesicle", "go_biological_process": "GO:0017156 calcium-ion regulated exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQ91-1", "uniprot_id": [ { "id": "A0A061IQ91_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQ91", "type": "external" } ], "mass": 73233.0, "length": 638, "protein_name": "Microtubule-associated protein 9", "gene_name": "Map9", "organism": "Hamster", "refseq_name": "microtubule-associated protein 9", "refseq_ac": [ { "id": "XP_003499528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499528", "type": "external" } ], "gene_names_uniprotkb": "Map9; H671_1g1625", "gene_names_refseq": "Map9", "protein_names_uniprotkb": "Microtubule-associated protein 9", "protein_names_refseq": "microtubule-associated protein 9", "tax_id": 10029, "disease": "", "pathway": " (cge:100773111)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613739.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0000235 astral microtubule;GO:1990023 mitotic spindle midzone", "go_biological_process": "GO:0046602 regulation of mitotic centrosome separation;GO:0090307 mitotic spindle assembly;GO:0000281 mitotic cytokinesis;GO:0060236 regulation of mitotic spindle organization;GO:1902412 regulation of mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQ91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQA5-1", "uniprot_id": [ { "id": "A0A061IQA5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQA5", "type": "external" } ], "mass": 104802.0, "length": 952, "protein_name": "Protocadherin-20", "gene_name": "Pcdh20", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pcdh20; H671_1g2417", "gene_names_refseq": "", "protein_names_uniprotkb": "Protocadherin-20", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100757789)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Potential calcium-dependent cell-adhesion protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQA5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQB6-1", "uniprot_id": [ { "id": "A0A061IQB6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQB6", "type": "external" } ], "mass": 68273.0, "length": 613, "protein_name": "RNA polymerase II elongation factor ELL isoform X2; RNA polymerase II elongation factor ELL-like protein", "gene_name": "Ell", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ell; H671_1g1141", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA polymerase II elongation factor ELL isoform X2; RNA polymerase II elongation factor ELL-like protein", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100767546)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003746 translation elongation factor activity;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0008023 transcription elongation factor complex;GO:0016607 nuclear speck;GO:0015030 Cajal body;GO:0000791 euchromatin", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0045945 positive regulation of transcription by RNA polymerase III;GO:0006368 transcription elongation by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0042795 snRNA transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQB7-1", "uniprot_id": [ { "id": "A0A061IQB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQB7", "type": "external" } ], "mass": 56033.0, "length": 508, "protein_name": "1.14.13.13; 25-hydroxyvitamin D-1 alpha hydroxylase; Cytochrome P450, family 27, subfamily b, polypeptide 1", "gene_name": "LOC100760414", "organism": "Hamster", "refseq_name": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "refseq_ac": [ { "id": "XP_003507561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507561", "type": "external" } ], "gene_names_uniprotkb": "LOC100760414; H671_1g1547", "gene_names_refseq": "LOC100760414", "protein_names_uniprotkb": "1.14.13.13; 25-hydroxyvitamin D-1 alpha hydroxylase; Cytochrome P450, family 27, subfamily b, polypeptide 1", "protein_names_refseq": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100760414)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614393.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004498 calcidiol 1-monooxygenase activity;GO:0062185 secalciferol 1-monooxygenase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0042369 vitamin D catabolic process;GO:0008203 cholesterol metabolic process;GO:0008285 negative regulation of cell population proliferation;GO:0032496 response to lipopolysaccharide;GO:0006816 calcium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQC5-1", "uniprot_id": [ { "id": "A0A061IQC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQC5", "type": "external" } ], "mass": 118328.0, "length": 1065, "protein_name": "SURP and G patch domain containing 2; SURP and G-patch domain-containing protein 2", "gene_name": "Sugp2", "organism": "Hamster", "refseq_name": "SURP and G-patch domain-containing protein 2 isoform X1", "refseq_ac": [ { "id": "XP_003499193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499193", "type": "external" } ], "gene_names_uniprotkb": "Sugp2; H671_1g1157", "gene_names_refseq": "Sugp2", "protein_names_uniprotkb": "SURP and G patch domain containing 2; SURP and G-patch domain-containing protein 2", "protein_names_refseq": "SURP and G-patch domain-containing protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754204)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQC5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQC9-1", "uniprot_id": [ { "id": "A0A061IQC9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQC9", "type": "external" } ], "mass": 101596.0, "length": 1006, "protein_name": "Methyl-CpG-binding domain protein 6", "gene_name": "Mbd6", "organism": "Hamster", "refseq_name": "methyl-CpG-binding domain protein 6 isoform X1", "refseq_ac": [ { "id": "XP_027248030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248030", "type": "external" } ], "gene_names_uniprotkb": "Mbd6; H671_1g1560", "gene_names_refseq": "Mbd6", "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 6", "protein_names_refseq": "methyl-CpG-binding domain protein 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757235)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0010369 chromocenter", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQC9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQD3-1", "uniprot_id": [ { "id": "A0A061IQD3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQD3", "type": "external" } ], "mass": 9992.0, "length": 87, "protein_name": "1.6.5.3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2", "gene_name": "Ndufa4l2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ndufa4l2; H671_1g1568", "gene_names_refseq": "", "protein_names_uniprotkb": "1.6.5.3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100755007)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQD4-1", "uniprot_id": [ { "id": "A0A061IQD4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQD4", "type": "external" } ], "mass": 132533.0, "length": 1201, "protein_name": "Endoplasmic reticulum transmembrane helix translocase", "gene_name": "Atp13a1; Gmip", "organism": "Hamster", "refseq_name": "manganese-transporting ATPase 13A1 isoform X2", "refseq_ac": [ { "id": "XP_027250404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250404", "type": "external" } ], "gene_names_uniprotkb": "Atp13a1; Gmip; H671_1g1170; I79_005061", "gene_names_refseq": "Atp13a1", "protein_names_uniprotkb": "Endoplasmic reticulum transmembrane helix translocase; Endoplasmic reticulum P5A-ATPase", "protein_names_refseq": "manganese-transporting ATPase 13A1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758734); (cge:100762605)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "21804562;23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051056 regulation of small GTPase mediated signal transduction;GO:0007264 small GTPase-mediated signal transduction;GO:0015031 protein transport;GO:0006874 intracellular calcium ion homeostasis;GO:0140569 extraction of mislocalized protein from ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A061IQD4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQD6-1", "uniprot_id": [ { "id": "A0A061IQD6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQD6", "type": "external" } ], "mass": 94950.0, "length": 853, "protein_name": "Signal transducer and activator of transcription", "gene_name": "Stat6", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Stat6; H671_1g1573", "gene_names_refseq": "", "protein_names_uniprotkb": "Signal transducer and activator of transcription", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100753838)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0019903 protein phosphatase binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0090575 RNA polymerase II transcription regulator complex;GO:0005634 nucleus", "go_biological_process": "GO:0035771 interleukin-4-mediated signaling pathway;GO:0002296 T-helper 1 cell lineage commitment;GO:0060443 mammary gland morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0002829 negative regulation of type 2 immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQD6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQE0-1", "uniprot_id": [ { "id": "A0A061IQE0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQE0", "type": "external" } ], "mass": 35398.0, "length": 310, "protein_name": "F-box only protein 28", "gene_name": "LOC118238516", "organism": "Hamster", "refseq_name": "F-box only protein 28-like", "refseq_ac": [ { "id": "XP_035308684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308684", "type": "external" } ], "gene_names_uniprotkb": "LOC118238516; H671_1g2318", "gene_names_refseq": "LOC118238516", "protein_names_uniprotkb": "F-box only protein 28", "protein_names_refseq": "F-box only protein 28-like", "tax_id": 10029, "disease": "", "pathway": " (cge:118238516)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQE0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQF6-1", "uniprot_id": [ { "id": "A0A061IQF6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQF6", "type": "external" } ], "mass": 32628.0, "length": 293, "protein_name": "Glycine N-methyltransferase", "gene_name": "LOC100769585", "organism": "Hamster", "refseq_name": "glycine N-methyltransferase", "refseq_ac": [ { "id": "XP_007644705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644705", "type": "external" } ], "gene_names_uniprotkb": "LOC100769585; H671_1g1509", "gene_names_refseq": "LOC100769585", "protein_names_uniprotkb": "Glycine N-methyltransferase; 2.1.1.20", "protein_names_refseq": "glycine N-methyltransferase", "tax_id": 10029, "disease": "", "pathway": " (cge:100769585)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614206.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007644705.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.20", "type": "external" } ], "go_molecular_function": "GO:0017174 glycine N-methyltransferase activity;GO:0042802 identical protein binding;GO:0005542 folic acid binding;GO:1904047 S-adenosyl-L-methionine binding;GO:0016594 glycine binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0005977 glycogen metabolic process;GO:0006730 one-carbon metabolic process;GO:0032259 methylation;GO:0046498 S-adenosylhomocysteine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQG1-1", "uniprot_id": [ { "id": "A0A061IQG1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQG1", "type": "external" } ], "mass": 29307.0, "length": 266, "protein_name": "Fibroblast growth factor", "gene_name": "Fgf5", "organism": "Hamster", "refseq_name": "fibroblast growth factor 5", "refseq_ac": [ { "id": "XP_003509211", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509211", "type": "external" } ], "gene_names_uniprotkb": "Fgf5; H671_1g1070", "gene_names_refseq": "Fgf5", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100763237)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614663.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0005104 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0051781 positive regulation of cell division;GO:0010001 glial cell differentiation;GO:0008543 fibroblast growth factor receptor signaling pathway;GO:0023019 signal transduction involved in regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQG8-1", "uniprot_id": [ { "id": "A0A061IQG8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQG8", "type": "external" } ], "mass": 40822.0, "length": 371, "protein_name": "Protein NDRG2", "gene_name": "Ndrg2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ndrg2; H671_1g2246", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein NDRG2", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100752580)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0030426 growth cone;GO:0005737 cytoplasm", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0016055 Wnt signaling pathway;GO:0001818 negative regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQG8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQH2-1", "uniprot_id": [ { "id": "A0A061IQH2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQH2", "type": "external" } ], "mass": 8283.0, "length": 73, "protein_name": "Homeodomain-only protein", "gene_name": "Hopx", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Hopx; H671_1g1058", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeodomain-only protein; Odd homeobox protein 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100757669)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0035033 histone deacetylase regulator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0048286 lung alveolus development;GO:0001829 trophectodermal cell differentiation;GO:0008016 regulation of heart contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQH8-1", "uniprot_id": [ { "id": "A0A061IQH8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQH8", "type": "external" } ], "mass": 39102.0, "length": 346, "protein_name": "DNA-directed RNA polymerases I and III subunit RPAC1", "gene_name": "Polr1c", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Polr1c; H671_1g1529", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA-directed RNA polymerases I and III subunit RPAC1; AC40; DNA-directed RNA polymerases I and III 40 kDa polypeptide; RPC40", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100758205)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0001650 fibrillar center;GO:0005736 RNA polymerase I complex;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQI3-1", "uniprot_id": [ { "id": "A0A061IQI3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQI3", "type": "external" } ], "mass": 52899.0, "length": 472, "protein_name": "Platelet glycoprotein 4", "gene_name": "Cd36", "organism": "Hamster", "refseq_name": "platelet glycoprotein 4", "refseq_ac": [ { "id": "XP_003504884", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504884", "type": "external" } ], "gene_names_uniprotkb": "Cd36; H671_1g1044", "gene_names_refseq": "Cd36", "protein_names_uniprotkb": "Platelet glycoprotein 4; Glycoprotein IIIb; PAS IV; PAS-4; Platelet glycoprotein IV", "protein_names_refseq": "platelet glycoprotein 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765055)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614092.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" } ], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0001540 amyloid-beta binding;GO:0008289 lipid binding;GO:0008035 high-density lipoprotein particle binding;GO:0005041 low-density lipoprotein particle receptor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0005901 caveola;GO:0031526 brush border membrane", "go_biological_process": "GO:1990379 lipid transport across blood-brain barrier;GO:0098900 regulation of action potential;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007155 cell adhesion;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQI7-1", "uniprot_id": [ { "id": "A0A061IQI7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQI7", "type": "external" } ], "mass": 34450.0, "length": 300, "protein_name": "Spermatogenesis-associated protein 4", "gene_name": "Spata4", "organism": "Hamster", "refseq_name": "spermatogenesis-associated protein 4", "refseq_ac": [ { "id": "XP_027246809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246809", "type": "external" } ], "gene_names_uniprotkb": "Spata4; H671_1g2234", "gene_names_refseq": "Spata4", "protein_names_uniprotkb": "Spermatogenesis-associated protein 4", "protein_names_refseq": "spermatogenesis-associated protein 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100752845)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in apoptosis regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005930 axoneme", "go_biological_process": "GO:0051493 regulation of cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQI7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQJ4-1", "uniprot_id": [ { "id": "A0A061IQJ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQJ4", "type": "external" } ], "mass": 78344.0, "length": 685, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp49", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 49 isoform X1", "refseq_ac": [ { "id": "XP_027250281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250281", "type": "external" } ], "gene_names_uniprotkb": "Usp49; H671_1g2231", "gene_names_refseq": "Usp49", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 49 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771034)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0004197 cysteine-type endopeptidase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0140936 histone H2B deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQL5-1", "uniprot_id": [ { "id": "A0A061IQL5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQL5", "type": "external" } ], "mass": 49387.0, "length": 482, "protein_name": "Otolin-1", "gene_name": "Otol1", "organism": "Hamster", "refseq_name": "otolin-1", "refseq_ac": [ { "id": "XP_003503308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503308", "type": "external" } ], "gene_names_uniprotkb": "Otol1; H671_1g2164", "gene_names_refseq": "Otol1", "protein_names_uniprotkb": "Otolin-1", "protein_names_refseq": "otolin-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755856)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613954.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005581 collagen trimer", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0045299 otolith mineralization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQM4-1", "uniprot_id": [ { "id": "A0A061IQM4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQM4", "type": "external" } ], "mass": 34689.0, "length": 321, "protein_name": "GDT1 family protein", "gene_name": "Tmem165", "organism": "Hamster", "refseq_name": "transmembrane protein 165 isoform X1", "refseq_ac": [ { "id": "XP_007650396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650396", "type": "external" } ], "gene_names_uniprotkb": "Tmem165; H671_1g1452", "gene_names_refseq": "Tmem165", "protein_names_uniprotkb": "GDT1 family protein", "protein_names_refseq": "transmembrane protein 165 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770946)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 429 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615191.1) and transcript sequence (IACG01087096.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007650396.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015085 calcium ion transmembrane transporter activity;GO:0005384 manganese ion transmembrane transporter activity", "go_cellular_component": "GO:0032588 trans-Golgi network membrane;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane;GO:0033106 cis-Golgi network membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0032468 Golgi calcium ion homeostasis;GO:0032472 Golgi calcium ion transport;GO:0035751 regulation of lysosomal lumen pH", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQM4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQN7-1", "uniprot_id": [ { "id": "A0A061IQN7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQN7", "type": "external" } ], "mass": 15384.0, "length": 133, "protein_name": "Uncharacterized protein C1orf54 homolog", "gene_name": "CUNH1orf54", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CUNH1orf54; H671_1g2057", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein C1orf54 homolog", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100761253)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQQ5-1", "uniprot_id": [ { "id": "A0A061IQQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQQ5", "type": "external" } ], "mass": 47767.0, "length": 418, "protein_name": "Lysophosphatidic acid phosphatase type 6", "gene_name": "Acp6", "organism": "Hamster", "refseq_name": "lysophosphatidic acid phosphatase type 6 isoform X1", "refseq_ac": [ { "id": "XP_035307148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307148", "type": "external" } ], "gene_names_uniprotkb": "Acp6; H671_1g1336", "gene_names_refseq": "Acp6", "protein_names_uniprotkb": "Lysophosphatidic acid phosphatase type 6; 3.1.3.2; Acid phosphatase 6, lysophosphatidic", "protein_names_refseq": "lysophosphatidic acid phosphatase type 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751531)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "3.1.3.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.76", "type": "external" }, { "id": "3.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4", "type": "external" }, { "id": "3.1.3.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106", "type": "external" }, { "id": "3.6.1.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75", "type": "external" } ], "go_molecular_function": "GO:0052642 lysophosphatidic acid phosphatase activity;GO:0003993 acid phosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:2001311 lysobisphosphatidic acid metabolic process;GO:0002244 hematopoietic progenitor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQR5-1", "uniprot_id": [ { "id": "A0A061IQR5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQR5", "type": "external" } ], "mass": 111193.0, "length": 1015, "protein_name": "Endosome/lysosome-associated apoptosis and autophagy regulator 1", "gene_name": "Elapor1", "organism": "Hamster", "refseq_name": "endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform X3", "refseq_ac": [ { "id": "XP_027251305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251305", "type": "external" } ], "gene_names_uniprotkb": "Elapor1; H671_1g1963", "gene_names_refseq": "Elapor1", "protein_names_uniprotkb": "Endosome/lysosome-associated apoptosis and autophagy regulator 1", "protein_names_refseq": "endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761426)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May protect cells from cell death by inducing cytosolic vacuolization and up-regulating the autophagy pathway. May play a role in apoptosis and cell proliferation through its interaction with HSPA5., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070062 extracellular exosome;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0044090 positive regulation of vacuole organization;GO:0009267 cellular response to starvation;GO:2000786 positive regulation of autophagosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQR5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQS6-1", "uniprot_id": [ { "id": "A0A061IQS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQS6", "type": "external" } ], "mass": 123265.0, "length": 1090, "protein_name": "Rho GTPase-activating protein 7", "gene_name": "Dlc1", "organism": "Hamster", "refseq_name": "rho GTPase-activating protein 7 isoform X1", "refseq_ac": [ { "id": "XP_027247032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247032", "type": "external" } ], "gene_names_uniprotkb": "Dlc1; H671_1g1928", "gene_names_refseq": "Dlc1", "protein_names_uniprotkb": "Rho GTPase-activating protein 7; Deleted in liver cancer 1 protein homolog; Rho-type GTPase-activating protein 7; START domain-containing protein 12; StAR-related lipid transfer protein 12", "protein_names_refseq": "rho GTPase-activating protein 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771649)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005925 focal adhesion;GO:0045121 membrane raft", "go_biological_process": "GO:0007165 signal transduction;GO:0030036 actin cytoskeleton organization;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQS6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQT4-1", "uniprot_id": [ { "id": "A0A061IQT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQT4", "type": "external" } ], "mass": 18766.0, "length": 169, "protein_name": "PrdX deacylase domain-containing protein 1", "gene_name": "LOC100765635", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100765635; H671_1g1293", "gene_names_refseq": "", "protein_names_uniprotkb": "PrdX deacylase domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100765635)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004812 aminoacyl-tRNA ligase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQU7-1", "uniprot_id": [ { "id": "A0A061IQU7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQU7", "type": "external" } ], "mass": 318013.0, "length": 2786, "protein_name": "Putative small subunit processome component 20 like protein; Small subunit processome component 20 homolog isoform X1", "gene_name": "Utp20", "organism": "Hamster", "refseq_name": "small subunit processome component 20 homolog isoform X1", "refseq_ac": [ { "id": "XP_027248380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248380", "type": "external" } ], "gene_names_uniprotkb": "Utp20; H671_1g1908", "gene_names_refseq": "Utp20", "protein_names_uniprotkb": "Putative small subunit processome component 20 like protein; Small subunit processome component 20 homolog isoform X1", "protein_names_refseq": "small subunit processome component 20 homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772924)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQU7-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQW3-1", "uniprot_id": [ { "id": "A0A061IQW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQW3", "type": "external" } ], "mass": 33203.0, "length": 284, "protein_name": "Nipsnap homolog 1", "gene_name": "Nipsnap1", "organism": "Hamster", "refseq_name": "protein NipSnap homolog 1", "refseq_ac": [ { "id": "XP_003505367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505367", "type": "external" } ], "gene_names_uniprotkb": "Nipsnap1; H671_1g1179", "gene_names_refseq": "Nipsnap1", "protein_names_uniprotkb": "Nipsnap homolog 1", "protein_names_refseq": "protein NipSnap homolog 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773900)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614142.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019233 sensory perception of pain;GO:0000423 mitophagy", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQX5-1", "uniprot_id": [ { "id": "A0A061IQX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQX5", "type": "external" } ], "mass": 31630.0, "length": 267, "protein_name": "Elongation of very long chain fatty acids protein 6", "gene_name": "LOC100763438", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100763438; ELOVL6; H671_1g1858", "gene_names_refseq": "", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 6; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL6; ELOVL FA elongase 6; ELOVL fatty acid elongase 6; Very long chain 3-ketoacyl-CoA synthase 6; Very long chain 3-oxoacyl-CoA synthase 6", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100763438)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQZ6-1", "uniprot_id": [ { "id": "A0A061IQZ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQZ6", "type": "external" } ], "mass": 29060.0, "length": 266, "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "Hpgd", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Hpgd; H671_1g1119", "gene_names_refseq": "", "protein_names_uniprotkb": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 1.1.1.141; 1.1.1.232; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; Prostaglandin dehydrogenase 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100755116)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Catalyzes the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding keto (oxo) metabolites. Decreases the levels of the pro-proliferative prostaglandins such as prostaglandin E2 (whose activity is increased in cancer because of an increase in the expression of cyclooxygenase 2) and generates oxo-fatty acid products that can profoundly influence cell function by abrogating pro-inflammatory cytokine expression. Converts resolvins E1, D1 and D2 to their oxo products, which represents a mode of resolvin inactivation. Resolvin E1 plays important roles during the resolution phase of acute inflammation, while resolvins D1 and D2 have a unique role in obesity-induced adipose inflammation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.141", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.141", "type": "external" }, { "id": "1.1.1.232", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.232", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0070403 NAD+ binding;GO:0004957 prostaglandin E receptor activity;GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0007565 female pregnancy;GO:0006693 prostaglandin metabolic process;GO:0045786 negative regulation of cell cycle;GO:0097070 ductus arteriosus closure", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IQZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR03-1", "uniprot_id": [ { "id": "A0A061IR03_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR03", "type": "external" } ], "mass": 133897.0, "length": 1174, "protein_name": "DNA-directed RNA polymerase subunit beta", "gene_name": "Polr2b", "organism": "Hamster", "refseq_name": "DNA-directed RNA polymerase II subunit RPB2 isoform X1", "refseq_ac": [ { "id": "XP_003511530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511530", "type": "external" } ], "gene_names_uniprotkb": "Polr2b; H671_1g1054", "gene_names_refseq": "Polr2b", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit beta; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755901)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615129.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]; RNA-dependent RNA polymerase that catalyzes the extension of a non-coding RNA (ncRNA) at the 3'-end using the four ribonucleoside triphosphates as substrates. An internal ncRNA sequence near the 3'-end serves as a template in a single-round Pol II-mediated RNA polymerization reaction. May decrease the stability of ncRNAs that repress Pol II-mediated gene transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" } ], "go_molecular_function": "GO:0003968 RNA-directed RNA polymerase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005665 RNA polymerase II, core complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR03-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR05-1", "uniprot_id": [ { "id": "A0A061IR05_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR05", "type": "external" } ], "mass": 74738.0, "length": 671, "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "Srp72", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Srp72; H671_1g1062", "gene_names_refseq": "", "protein_names_uniprotkb": "Signal recognition particle subunit SRP72", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100760440)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER. The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER. Binds the signal recognition particle RNA (7SL RNA) in presence of SRP68. Can bind 7SL RNA with low affinity. The SRP complex possibly participates in the elongation arrest function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030911 TPR domain binding;GO:0005047 signal recognition particle binding;GO:0043022 ribosome binding;GO:0008312 7S RNA binding", "go_cellular_component": "GO:0005786 signal recognition particle, endoplasmic reticulum targeting;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0006614 SRP-dependent cotranslational protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR05-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR51-1", "uniprot_id": [ { "id": "A0A061IR51_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR51", "type": "external" } ], "mass": 48189.0, "length": 407, "protein_name": "Tryptophan 2,3-dioxygenase", "gene_name": "Tdo2", "organism": "Hamster", "refseq_name": "tryptophan 2,3-dioxygenase", "refseq_ac": [ { "id": "XP_003499512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499512", "type": "external" } ], "gene_names_uniprotkb": "Tdo2; H671_1g1630; TDO2", "gene_names_refseq": "Tdo2", "protein_names_uniprotkb": "Tryptophan 2,3-dioxygenase; 1.13.11.11; TDO; TO; TRPO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase", "protein_names_refseq": "tryptophan 2,3-dioxygenase", "tax_id": 10029, "disease": "", "pathway": " (cge:100768126)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613739.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.13.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.11", "type": "external" }, { "id": "1.13.11.52", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.52", "type": "external" }, { "id": "1.13.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.-", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004833 tryptophan 2,3-dioxygenase activity", "go_cellular_component": "", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0051289 protein homotetramerization;GO:0019442 L-tryptophan catabolic process to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR51-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR64-1", "uniprot_id": [ { "id": "A0A061IR64_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR64", "type": "external" } ], "mass": 22870.0, "length": 203, "protein_name": "DNA damage-inducible transcript 3 protein", "gene_name": "Ddit3", "organism": "Hamster", "refseq_name": "DNA damage-inducible transcript 3 protein isoform X1", "refseq_ac": [ { "id": "XP_035306970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306970", "type": "external" } ], "gene_names_uniprotkb": "Ddit3; H671_1g1561", "gene_names_refseq": "Ddit3", "protein_names_uniprotkb": "DNA damage-inducible transcript 3 protein; C/EBP zeta; C/EBP-homologous protein 10; C/EBP-homologous protein; CCAAT/enhancer-binding protein homologous protein; DDIT-3; Growth arrest and DNA-damage-inducible protein GADD153", "protein_names_refseq": "DNA damage-inducible transcript 3 protein isoform X1", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0036488 CHOP-C/EBP complex;GO:0005737 cytoplasm;GO:1990622 CHOP-ATF3 complex;GO:1990617 CHOP-ATF4 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0016055 Wnt signaling pathway;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0006983 ER overload response;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR64-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR65-1", "uniprot_id": [ { "id": "A0A061IR65_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR65", "type": "external" } ], "mass": 117765.0, "length": 1105, "protein_name": "Zinc finger protein GLI1", "gene_name": "Gli1", "organism": "Hamster", "refseq_name": "zinc finger protein GLI1 isoform X1", "refseq_ac": [ { "id": "XP_027248013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248013", "type": "external" } ], "gene_names_uniprotkb": "Gli1; H671_1g1564", "gene_names_refseq": "Gli1", "protein_names_uniprotkb": "Zinc finger protein GLI1", "protein_names_refseq": "zinc finger protein GLI1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763229)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005930 axoneme", "go_biological_process": "GO:0030900 forebrain development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030324 lung development;GO:0009954 proximal/distal pattern formation;GO:0009953 dorsal/ventral pattern formation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR65-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR68-1", "uniprot_id": [ { "id": "A0A061IR68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR68", "type": "external" } ], "mass": 78304.0, "length": 703, "protein_name": "Zinc finger and BTB domain-containing protein 39", "gene_name": "Zbtb39", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zbtb39; H671_1g1577", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 39", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100752450)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR73-1", "uniprot_id": [ { "id": "PEX6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR73", "type": "external" } ], "mass": 104263.0, "length": 980, "protein_name": "Peroxisomal ATPase PEX6", "gene_name": "PEX6", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PEX6", "gene_names_refseq": "", "protein_names_uniprotkb": "Peroxisomal ATPase PEX6; 3.6.4.-; Peroxin-6; Peroxisomal biogenesis factor 6", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "21362118;21804562;23929341;9539740", "class_list": "", "function": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:23929341, PubMed:9539740). Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (By similarity). Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0140036 ubiquitin-modified protein reader activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0044877 protein-containing complex binding;GO:0140318 protein transporter activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0005829 cytosol;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0016561 protein import into peroxisome matrix, translocation;GO:0043335 protein unfolding;GO:0050821 protein stabilization;GO:0006625 protein targeting to peroxisome;GO:0016558 protein import into peroxisome matrix", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A061IR73-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR93-1", "uniprot_id": [ { "id": "A0A061IR93_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR93", "type": "external" } ], "mass": 150511.0, "length": 1343, "protein_name": "Vascular endothelial growth factor receptor 2", "gene_name": "Kdr", "organism": "Hamster", "refseq_name": "vascular endothelial growth factor receptor 2 isoform X2", "refseq_ac": [ { "id": "XP_027246714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246714", "type": "external" } ], "gene_names_uniprotkb": "Kdr; H671_1g1449", "gene_names_refseq": "Kdr", "protein_names_uniprotkb": "Vascular endothelial growth factor receptor 2; 2.7.10.1; Fetal liver kinase 1; Protein-tyrosine kinase receptor flk-1", "protein_names_refseq": "vascular endothelial growth factor receptor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756294)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0046872 metal ion binding;GO:0005021 vascular endothelial growth factor receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0060562 epithelial tube morphogenesis;GO:0001525 angiogenesis;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR93-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR94-1", "uniprot_id": [ { "id": "A0A061IR94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR94", "type": "external" } ], "mass": 97935.0, "length": 866, "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "Clock", "organism": "Hamster", "refseq_name": "circadian locomoter output cycles protein kaput isoform X1", "refseq_ac": [ { "id": "XP_027246717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246717", "type": "external" } ], "gene_names_uniprotkb": "Clock; H671_1g1453", "gene_names_refseq": "Clock", "protein_names_uniprotkb": "Circadian locomoter output cycles protein kaput; 2.3.1.48", "protein_names_refseq": "circadian locomoter output cycles protein kaput isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770092)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.259", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.259", "type": "external" } ], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding;GO:0004402 histone acetyltransferase activity", "go_cellular_component": "GO:1990513 CLOCK-BMAL transcription complex;GO:0005829 cytosol", "go_biological_process": "GO:0006974 DNA damage response;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR99-1", "uniprot_id": [ { "id": "A0A061IR99_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR99", "type": "external" } ], "mass": 28364.0, "length": 259, "protein_name": "Dickkopf WNT signaling pathway inhibitor 2; Dickkopf-related protein 2", "gene_name": "Dkk2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dkk2; H671_1g1406", "gene_names_refseq": "", "protein_names_uniprotkb": "Dickkopf WNT signaling pathway inhibitor 2; Dickkopf-related protein 2", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100774823)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0048019 receptor antagonist activity;GO:0039706 co-receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IR99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRA2-1", "uniprot_id": [ { "id": "A0A061IRA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRA2", "type": "external" } ], "mass": 112272.0, "length": 981, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp15", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 15 isoform X1", "refseq_ac": [ { "id": "XP_007639707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639707", "type": "external" } ], "gene_names_uniprotkb": "Usp15; H671_1g1368", "gene_names_refseq": "Usp15", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 15 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759035)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 100 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613811.1) and transcript sequence (JI873397.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0061649 ubiquitin-modified histone reader activity;GO:0042802 identical protein binding;GO:0005160 transforming growth factor beta receptor binding;GO:0046332 SMAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016604 nuclear body", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0051252 regulation of RNA metabolic process;GO:1905035 negative regulation of antifungal innate immune response;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRA2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRA8-1", "uniprot_id": [ { "id": "A0A061IRA8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRA8", "type": "external" } ], "mass": 56574.0, "length": 519, "protein_name": "Na/Pi cotransporter C-terminal-associated protein 1", "gene_name": "Pdzk1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pdzk1; H671_1g1340", "gene_names_refseq": "", "protein_names_uniprotkb": "Na/Pi cotransporter C-terminal-associated protein 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100752699)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0030165 PDZ domain binding;GO:0043495 membrane-membrane adaptor activity;GO:0141109 transporter activator activity", "go_cellular_component": "GO:0005903 brush border;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:1902603 carnitine transmembrane transport;GO:1905477 positive regulation of protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRA8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRA9-1", "uniprot_id": [ { "id": "A0A061IRA9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRA9", "type": "external" } ], "mass": 32461.0, "length": 294, "protein_name": "m7GpppN-mRNA hydrolase NUDT17", "gene_name": "Nudt17", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nudt17; H671_1g1344", "gene_names_refseq": "", "protein_names_uniprotkb": "m7GpppN-mRNA hydrolase NUDT17; 3.6.1.62; Nucleoside diphosphate-linked moiety X motif 17", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100753597)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Acts as a decapping enzyme capable of hydrolyzing monomethylated capped RNAs (in vitro). Hydrolyzes monomethylated capped RNA after alpha and beta phosphates to form N(7)-methyl-GDP. Shows low activity towards unmethylated capped RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0035529 NADH pyrophosphatase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0019677 NAD+ catabolic process;GO:0006742 NADP+ catabolic process;GO:0006734 NADH metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRB1-1", "uniprot_id": [ { "id": "A0A061IRB1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRB1", "type": "external" } ], "mass": 44611.0, "length": 399, "protein_name": "Thioredoxin-interacting protein", "gene_name": "Txnip", "organism": "Hamster", "refseq_name": "thioredoxin-interacting protein", "refseq_ac": [ { "id": "XP_003498669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498669", "type": "external" } ], "gene_names_uniprotkb": "Txnip; H671_1g1353", "gene_names_refseq": "Txnip", "protein_names_uniprotkb": "Thioredoxin-interacting protein; Vitamin D3 up-regulated protein 1", "protein_names_refseq": "thioredoxin-interacting protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100756038)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613699.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0071228 cellular response to tumor cell;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006979 response to oxidative stress;GO:0030216 keratinocyte differentiation;GO:0048008 platelet-derived growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRB6-1", "uniprot_id": [ { "id": "A0A061IRB6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRB6", "type": "external" } ], "mass": 48776.0, "length": 437, "protein_name": "Exosome complex component RRP45", "gene_name": "Exosc9", "organism": "Hamster", "refseq_name": "exosome complex component RRP45", "refseq_ac": [ { "id": "XP_003510416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510416", "type": "external" } ], "gene_names_uniprotkb": "Exosc9; H671_1g1310", "gene_names_refseq": "Exosc9", "protein_names_uniprotkb": "Exosome complex component RRP45; Exosome component 9", "protein_names_refseq": "exosome complex component RRP45", "tax_id": 10029, "disease": "", "pathway": " (cge:100759081)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614868.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000176 nuclear exosome (RNase complex);GO:0000228 nuclear chromosome", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0034473 U1 snRNA 3'-end processing;GO:0034476 U5 snRNA 3'-end processing;GO:0030307 positive regulation of cell growth;GO:0016075 rRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRC5-1", "uniprot_id": [ { "id": "A0A061IRC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRC5", "type": "external" } ], "mass": 15031.0, "length": 135, "protein_name": "Helix-loop-helix protein 1; Helix-loop-helix protein 2; Nescient helix loop helix 2", "gene_name": "LOC113833176", "organism": "Hamster", "refseq_name": "helix-loop-helix protein 2", "refseq_ac": [ { "id": "XP_035306447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306447", "type": "external" } ], "gene_names_uniprotkb": "LOC113833176; H671_1g1290", "gene_names_refseq": "LOC113833176", "protein_names_uniprotkb": "Helix-loop-helix protein 1; Helix-loop-helix protein 2; Nescient helix loop helix 2", "protein_names_refseq": "helix-loop-helix protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:113833176)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0001223 transcription coactivator binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0060179 male mating behavior;GO:0006915 apoptotic process;GO:0008584 male gonad development;GO:0007422 peripheral nervous system development;GO:0021535 cell migration in hindbrain", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRE0-1", "uniprot_id": [ { "id": "A0A061IRE0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRE0", "type": "external" } ], "mass": 72146.0, "length": 678, "protein_name": "GAS2-like protein 1; Growth arrest-specific 2 like 1", "gene_name": "Gas2l1", "organism": "Hamster", "refseq_name": "GAS2-like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_016832567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832567", "type": "external" } ], "gene_names_uniprotkb": "Gas2l1; H671_1g1183", "gene_names_refseq": "Gas2l1", "protein_names_uniprotkb": "GAS2-like protein 1; Growth arrest-specific 2 like 1", "protein_names_refseq": "GAS2-like protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773328)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614142.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0051015 actin filament binding;GO:0008093 cytoskeletal anchor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005884 actin filament;GO:0001725 stress fiber;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0051764 actin crosslink formation;GO:0001578 microtubule bundle formation;GO:1904825 protein localization to microtubule plus-end", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRE0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRE8-1", "uniprot_id": [ { "id": "A0A061IRE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRE8", "type": "external" } ], "mass": 38933.0, "length": 357, "protein_name": "Embryonic growth/differentiation factor 1-like; Growth/differentiation factor 3-like protein", "gene_name": "LOC113833389", "organism": "Hamster", "refseq_name": "embryonic growth/differentiation factor 1-like", "refseq_ac": [ { "id": "XP_027250484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250484", "type": "external" } ], "gene_names_uniprotkb": "LOC113833389; H671_1g1152", "gene_names_refseq": "LOC113833389", "protein_names_uniprotkb": "Embryonic growth/differentiation factor 1-like; Growth/differentiation factor 3-like protein", "protein_names_refseq": "embryonic growth/differentiation factor 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113833389)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRF3-1", "uniprot_id": [ { "id": "A0A061IRF3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRF3", "type": "external" } ], "mass": 39231.0, "length": 348, "protein_name": "Lysophosphatidic acid receptor", "gene_name": "Lpar2", "organism": "Hamster", "refseq_name": "lysophosphatidic acid receptor 2", "refseq_ac": [ { "id": "XP_003499110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499110", "type": "external" } ], "gene_names_uniprotkb": "Lpar2; H671_1g1169", "gene_names_refseq": "Lpar2", "protein_names_uniprotkb": "Lysophosphatidic acid receptor", "protein_names_refseq": "lysophosphatidic acid receptor 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753903)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030165 PDZ domain binding;GO:0070915 lysophosphatidic acid receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0048787 presynaptic active zone membrane;GO:0009986 cell surface;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0035025 positive regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A061IRF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A067XGA8-1", "uniprot_id": [ { "id": "A0A067XGA8_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A067XGA8", "type": "external" } ], "mass": 60938.0, "length": 543, "protein_name": "Zinc finger protein 280B isoform a; Zinc finger protein 280B-like", "gene_name": "ZNF280BY", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ZNF280BY; LOC132344716", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 280B isoform a; Zinc finger protein 280B-like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "21214936", "class_list": "", "function": "May function as a transcription factor., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A067XGA8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A067XGF5-1", "uniprot_id": [ { "id": "A0A067XGF5_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A067XGF5", "type": "external" } ], "mass": 47284.0, "length": 424, "protein_name": "Zinc finger protein 280B isoform c", "gene_name": "LOC104974629", "organism": "Bovine", "refseq_name": "zinc finger protein 280B-like", "refseq_ac": [ { "id": "NP_001306819", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001306819", "type": "external" } ], "gene_names_uniprotkb": "LOC104974629", "gene_names_refseq": "LOC104974629", "protein_names_uniprotkb": "Zinc finger protein 280B isoform c", "protein_names_refseq": "zinc finger protein 280B-like; zinc finger protein 280B", "tax_id": 9913, "disease": "", "pathway": " (bta:104974629)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21214936", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A067XGF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A068F143-1", "uniprot_id": [ { "id": "A0A068F143_PIG", "url": "https://www.uniprot.org/uniprot/A0A068F143", "type": "external" } ], "mass": 22663.0, "length": 206, "protein_name": "Glutathione peroxidase", "gene_name": "GPX1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GPX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutathione peroxidase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004602 glutathione peroxidase activity;GO:0017124 SH3 domain binding;GO:1990782 protein tyrosine kinase binding;GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0097413 Lewy body", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0043403 skeletal muscle tissue regeneration;GO:0051702 biological process involved in interaction with symbiont;GO:0009609 response to symbiotic bacterium;GO:0001659 temperature homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A068F143-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000010000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A068F5P3-1", "uniprot_id": [ { "id": "A0A068F5P3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A068F5P3", "type": "external" } ], "mass": 55865.0, "length": 493, "protein_name": "2.4.1.122; Beta-1,3-glucosyltransferase precursor; Beta-3-glucosyltransferase b", "gene_name": "b3glctb", "organism": "Zebrafish", "refseq_name": "beta-1,3-glucosyltransferase precursor", "refseq_ac": [ { "id": "NP_001289177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289177", "type": "external" } ], "gene_names_uniprotkb": "b3glctb; b3galtlb; si:dkey-189i22.3", "gene_names_refseq": "b3galtlb; b3glctb; si:dkey-189i22.3", "protein_names_uniprotkb": "2.4.1.122; Beta-1,3-glucosyltransferase precursor; Beta-3-glucosyltransferase b", "protein_names_refseq": "beta 1,3-galactosyltransferase-like b; beta-1,3-glucosyltransferase precursor", "tax_id": 7955, "disease": "Peters plus syndrome (Disease Ontology:DOID:0080201)", "pathway": " (dre:564156)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;28252024;28926587", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KJ680290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN18715637 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KJ680290.1. On Oct 7, 2014 this sequence version replaced XP_009303781.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008375 acetylglucosaminyltransferase activity;GO:0016757 glycosyltransferase activity;GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A068F5P3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A068F9P7-1", "uniprot_id": [ { "id": "A0A068F9P7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A068F9P7", "type": "external" } ], "mass": 56192.0, "length": 496, "protein_name": "2.4.1.122; Beta-3-glucosyltransferase a", "gene_name": "b3glcta", "organism": "Zebrafish", "refseq_name": "beta 3-glucosyltransferase a", "refseq_ac": [ { "id": "NP_001289180", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289180", "type": "external" } ], "gene_names_uniprotkb": "b3glcta; b3galtla; si:dkey-1o1.2", "gene_names_refseq": "b3galtla; b3glcta; si:dkey-1o1.2", "protein_names_uniprotkb": "2.4.1.122; Beta-3-glucosyltransferase a", "protein_names_refseq": "b3galtl; beta 1,3-galactosyltransferase-like a; beta 3-glucosyltransferase a", "tax_id": 7955, "disease": "Peters plus syndrome (Disease Ontology:DOID:0080201)", "pathway": " (dre:799443); (R-DRE-5173214)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "23594743;26469318;27189481;27773705;28926587", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KJ680289.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KJ680289.1., [RefSeq]; The zebrafish orthologs of b3glcta show significant sequence and functional conservation but have no apparent effect on normal zebrafish development when disrupted by genetic mutations. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1L3", "ec_number_list": [ { "id": "2.4.1.122", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.122", "type": "external" } ], "go_molecular_function": "GO:0008375 acetylglucosaminyltransferase activity;GO:0016757 glycosyltransferase activity;GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A068F9P7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A068FNU8-1", "uniprot_id": [ { "id": "A0A068FNU8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A068FNU8", "type": "external" } ], "mass": 54342.0, "length": 474, "protein_name": "Interferon-induced protein with tetratricopeptide repeats", "gene_name": "ifit9", "organism": "Zebrafish", "refseq_name": "interferon-induced protein with tetratricopeptide repeats 9 isoform 1", "refseq_ac": [ { "id": "NP_001315640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315640", "type": "external" } ], "gene_names_uniprotkb": "ifit9; IFIT12A; si:dkey-26g8.12", "gene_names_refseq": "ifit9; si:dkey-26g8.12", "protein_names_uniprotkb": "Interferon-induced protein with tetratricopeptide repeats", "protein_names_refseq": "Ifit12a; interferon-induced protein with tetratricopeptide repeats 9 isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:567384)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23594743;23818968;24683187;24950240;28789986", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.25525351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 9, 2025 this sequence version replaced NP_001315640.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A068FNU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A068FR00-1", "uniprot_id": [ { "id": "A0A068FR00_DANRE", "url": "https://www.uniprot.org/uniprot/A0A068FR00", "type": "external" } ], "mass": 34929.0, "length": 302, "protein_name": "Interferon-induced protein with tetratricopeptide repeats", "gene_name": "IFIT12D", "organism": "Zebrafish", "refseq_name": "interferon-induced protein with tetratricopeptide repeats 5-like", "refseq_ac": [ { "id": "NP_001306199", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001306199", "type": "external" } ], "gene_names_uniprotkb": "IFIT12D; LOC100537930", "gene_names_refseq": "IFIT12D; LOC100537930", "protein_names_uniprotkb": "Interferon-induced protein with tetratricopeptide repeats", "protein_names_refseq": "interferon-induced protein with tetratricopeptide repeats 5-like", "tax_id": 7955, "disease": "", "pathway": " (dre:100537930)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;24950240", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KF418358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476772, SAMEA708828 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KF418358.1. 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The reference sequence was derived from EE716637.1 and KF418363.1. 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Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. 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Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 6, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 53.3, "record_id": "A0A075B6P5-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6Q5-1", "uniprot_id": [ { "id": "HV364_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6Q5", "type": "external" } ], "mass": 12891.0, "length": 118, "protein_name": "Immunoglobulin heavy variable 3-64", "gene_name": "IGHV3-64", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV3-64", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy variable 3-64", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 9, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;28832583;29242379;29786170;35580925", "class_list": "", "function": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A075B6Q5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6R0-1", "uniprot_id": [ { "id": "TRGV2_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6R0", "type": "external" } ], "mass": 13310.0, "length": 118, "protein_name": "T cell receptor gamma variable 2", "gene_name": "TRGV2", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGV2; TCRGV2", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor gamma variable 2", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "23348415;24387714;24600447;25674089;28920588", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A075B6R0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6R2-1", "uniprot_id": [ { "id": "HV404_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6R2", "type": "external" } ], "mass": 12848.0, "length": 117, "protein_name": "Immunoglobulin heavy variable 4-4", "gene_name": "IGHV4-4", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV4-4", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy variable 4-4", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;29557506;32350084;32357974", "class_list": "", "function": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A075B6R2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6R9-1", "uniprot_id": [ { "id": "KVD24_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6R9", "type": "external" } ], "mass": 13079.0, "length": 120, "protein_name": "Probable non-functional immunoglobulin kappa variable 2D-24", "gene_name": "IGKV2D-24", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV2D-24", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional immunoglobulin kappa variable 2D-24", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A075B6R9-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6S0-1", "uniprot_id": [ { "id": "TRGJ1_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6S0", "type": "external" } ], "mass": 1791.0, "length": 16, "protein_name": "T cell receptor gamma joining 1", "gene_name": "TRGJ1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGJ1; TCRGJ1", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor gamma joining 1", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "23348415;24387714;24600447;25674089;28920588", "class_list": "", "function": "J region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. 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The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 10, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A087X0P6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A075B6S2-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6S4-1", "uniprot_id": [ { "id": "KVD17_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6S4", "type": "external" } ], "mass": 12835.0, "length": 117, "protein_name": "Immunoglobulin kappa variable 1D-17", "gene_name": "IGKV1D-17", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV1D-17", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin kappa variable 1D-17", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "11549845;17576170;20176268;22158414;24600447;32350084;35051231", "class_list": "", "function": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). 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"class_list": "", "function": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 53.6, "record_id": "A0A075B6S6-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6S9-1", "uniprot_id": [ { "id": "KV137_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6S9", "type": "external" } ], "mass": 12688.0, "length": 117, "protein_name": "Probable non-functional immunoglobulinn kappa variable 1-37", "gene_name": "IGKV1-37", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV1-37", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional immunoglobulinn kappa variable 1-37", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 9, "publication_id_list": "11340299;17576170;20176268;22158414;24600447;34357683;35051231;35580925;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0A0MT75;A0A0E3D6N1;A0A0U1RVJ2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A075B6S9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6T6-1", "uniprot_id": [ { "id": "TVAL2_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6T6", "type": "external" } ], "mass": 12838.0, "length": 113, "protein_name": "T cell receptor alpha variable 12-2", "gene_name": "TRAV12-2", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAV12-2", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha variable 12-2", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;8906788", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0042101 T cell receptor complex", "go_biological_process": "GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A075B6T6-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6T7-1", "uniprot_id": [ { "id": "TVA6_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6T7", "type": "external" } ], "mass": 15362.0, "length": 132, "protein_name": "T cell receptor alpha variable 6", "gene_name": "TRAV6", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAV6; TCRAV5S1", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha variable 6", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex", "go_biological_process": "GO:0009617 response to bacterium;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A075B6T7-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A075B6T8-1", "uniprot_id": [ { "id": "TVA91_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A075B6T8", "type": "external" } ], "mass": 12354.0, "length": 112, "protein_name": "T cell receptor alpha variable 9-1", "gene_name": "TRAV9-1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAV9-1", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha variable 9-1", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;35051231", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. 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The reference sequence was derived from JX844127.1. 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Does not act on RAB4 or RAB11 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A087WVF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087WW49-1", "uniprot_id": [ { "id": "A0A087WW49_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087WW49", "type": "external" } ], "mass": 12944.0, "length": 117, "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC102724971", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC102724971", "gene_names_refseq": "", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11237011", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A087WW49-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087WW87-1", "uniprot_id": [ { "id": "KV240_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087WW87", "type": "external" } ], "mass": 13310.0, "length": 121, "protein_name": "Immunoglobulin kappa variable 2-40", "gene_name": "IGKV2-40", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGKV2-40", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin kappa variable 2-40", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "11549845;17576170;20176268;22158414;24600447;32350084", "class_list": "", "function": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A087WW87-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087WWA1-1", "uniprot_id": [ { "id": "P3URF_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087WWA1", "type": "external" } ], "mass": 10952.0, "length": 95, "protein_name": "PIK3R3 upstream open reading frame protein", "gene_name": "P3R3URF", "organism": "Human", "refseq_name": "P3R3URF protein", "refseq_ac": [ { "id": "NP_001315584", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315584", "type": "external" } ], "gene_names_uniprotkb": "P3R3URF", "gene_names_refseq": "P3R3URF", "protein_names_uniprotkb": "PIK3R3 upstream open reading frame protein", "protein_names_refseq": "P3R3URF protein; 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Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis., [UniProtKB, UniProtKB]; Single marker analysis indicated that SNP5 (rs1355095) in LOC728637 is associated with schizophrenia in Han Chinese., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 8, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A0A0A8IBZ9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000776 kinetochore;GO:0000779 condensed chromosome, centromeric region", "go_biological_process": "GO:0045143 homologous chromosome segregation;GO:0007060 male meiosis chromosome segregation;GO:0010789 meiotic sister chromatid cohesion involved in meiosis I;GO:0016321 female meiosis chromosome segregation;GO:0051754 meiotic sister chromatid cohesion, centromeric", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A087WXM9-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0100000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087WXS9-1", "uniprot_id": [ { "id": "TBC3I_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087WXS9", "type": "external" } ], "mass": 62205.0, "length": 549, "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "organism": "Human", "refseq_name": "TBC1 domain family member 3I", "refseq_ac": [ { "id": "NP_001278392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278392", "type": "external" } ], "gene_names_uniprotkb": "TBC1D3I", "gene_names_refseq": "PRC17; TBC1D3A; TBC1D3I; TBC1D3", "protein_names_uniprotkb": "TBC1 domain family member 3I", "protein_names_refseq": "Prostate cancer gene 17 protein; Protein TRE17-alpha; Rab GTPase-activating protein PRC17; TBC1 domain family member 3I; TBC1 domain family member 3; TBC1 domain family member-like", "tax_id": 9606, "disease": "", "pathway": " (hsa:102724862)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11237011;21030649;34509645", "class_list": "", "function": "Acts as a GTPase activating protein for RAB5. 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"0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087X096-1", "uniprot_id": [ { "id": "A0A087X096_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087X096", "type": "external" } ], "mass": 2202.0, "length": 22, "protein_name": "T cell receptor alpha joining 37", "gene_name": "TRAJ37", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAJ37", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha joining 37", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11237011;35108401", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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"record_id": "A0A087X096-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087X0K7-1", "uniprot_id": [ { "id": "TVB17_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087X0K7", "type": "external" } ], "mass": 12963.0, "length": 114, "protein_name": "Probable non-functional T cell receptor beta variable 17", "gene_name": "TRBV17", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV17", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor beta variable 17", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A087X0K7-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087X0M5-1", "uniprot_id": [ { "id": "TVB18_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087X0M5", "type": "external" } ], "mass": 13028.0, "length": 115, "protein_name": "T cell receptor beta variable 18", "gene_name": "TRBV18", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV18", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor beta variable 18", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A087X0M5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087X179-1", "uniprot_id": [ { "id": "TBC3E_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087X179", "type": "external" } ], "mass": 62131.0, "length": 549, "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "organism": "Human", "refseq_name": "TBC1 domain family member 3E", "refseq_ac": [ { "id": "NP_001278395", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278395", "type": "external" } ], "gene_names_uniprotkb": "TBC1D3E", "gene_names_refseq": "PRC17; TBC1D3A; TBC1D3E; TBC1D3; TBC1DE3", "protein_names_uniprotkb": "TBC1 domain family member 3E", "protein_names_refseq": "Prostate cancer gene 17 protein; Protein TRE17-alpha; Rab GTPase-activating protein PRC17; TBC1 domain family member 3E; TBC1 domain family member 3; TBC1 domain family member-like", "tax_id": 9606, "disease": "", "pathway": " (hsa:102723859)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16863688;21030649", "class_list": "", "function": "Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A087X179-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087X1C5-1", "uniprot_id": [ { "id": "CP2D7_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087X1C5", "type": "external" } ], "mass": 57489.0, "length": 515, "protein_name": "Cytochrome P450 2D7", "gene_name": "CYP2D7", "organism": "Human", "refseq_name": "cytochrome P450 2D7", "refseq_ac": [ { "id": "NP_001335315", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335315", "type": "external" } ], "gene_names_uniprotkb": "CYP2D7", "gene_names_refseq": "CYP2D6; CYP2D7AP; CYP2D7P1; CYP2D7P; CYP2D7; CYP2D@; CYP2D; P450C2D; P450DB1; RNA40057", "protein_names_uniprotkb": "Cytochrome P450 2D7; 1.14.14.1", "protein_names_refseq": "Putative cytochrome P450 2D7; cytochrome P450 2D7; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1; cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 1; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing) cluster; cytochrome P4502D6; nonfunctional cytochrome P450 family 2 subfamily D polypeptide 6", "tax_id": 9606, "disease": "calcium oxalate nephrolithiasis (Disease Ontology:DOID:0080652); traumatic brain injury (Disease Ontology:DOID:0081292); Sturge-Weber syndrome (Disease Ontology:DOID:0111563); spondylometaphyseal dysplasia corner fracture type (Disease Ontology:DOID:0112297); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); diabetic angiopathy (Disease Ontology:DOID:11713); iron deficiency anemia (Disease Ontology:DOID:11758); submandibular gland disease (Disease Ontology:DOID:12897); VACTERL association (Disease Ontology:DOID:14679); renovascular hypertension (Disease Ontology:DOID:1591); depressive disorder (Disease Ontology:DOID:1596); membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); glomerulonephritis (Disease Ontology:DOID:2921); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); renal cell carcinoma (Disease Ontology:DOID:4450); ureteral obstruction (Disease Ontology:DOID:5199); myocardial infarction (Disease Ontology:DOID:5844); end stage renal disease (Disease Ontology:DOID:783); osteoarthritis (Disease Ontology:DOID:8398); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": " (hsa:1564)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "15051713;16169517;17494644;18838503;29557506;30040020;31154438;37938771;39060884", "class_list": "", "function": "Association Between CYP2D7 and TCF20 Polymorphisms and Coronary Heart Disease., [RefSeq, PubMed]; May be responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It may be involved in the metabolism of codeine to morphine (PubMed:15051713). However, another study could not confirm it (PubMed:18838503)., [UniProtKB, PubMed, PubMed]; The loss of the stop codon in CYP2D7 does not result in the generation of enzymatically active protein in human liver., [RefSeq, PubMed]; This gene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is a segregating pseudogene, where some individuals may have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. In this case, the functional allele is thought to be rare. This locus is part of a cluster of cytochrome P450 genes on chromosome 22. [provided by RefSeq, Jan 2017]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q6XP50", "ec_number_list": [ { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "4.2.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.152", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" }, { "id": "1.14.14.55", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.55", "type": "external" }, { "id": "1.14.14.56", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.56", "type": "external" }, { "id": "1.14.14.73", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.73", "type": "external" }, { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.51", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.51", "type": "external" }, { "id": "1.14.14.52", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.52", "type": "external" }, { "id": "1.14.14.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.53", "type": "external" }, { "id": "1.14.14.75", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.75", "type": "external" }, { "id": "1.14.14.78", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.78", "type": "external" }, { "id": "1.14.14.79", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.79", "type": "external" }, { "id": "1.14.14.94", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.94", "type": "external" }, { "id": "1.14.14.80", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.80", "type": "external" }, { "id": "1.14.14.130", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.130", "type": "external" } ], "go_molecular_function": "GO:0070330 aromatase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0016020 membrane;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0042178 xenobiotic catabolic process;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A087X1C5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A087X1G2-1", "uniprot_id": [ { "id": "TBC3K_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A087X1G2", "type": "external" } ], "mass": 62171.0, "length": 549, "protein_name": "TBC1 domain family member 3K", "gene_name": "TBC1D3K", "organism": "Human", "refseq_name": "TBC1 domain family member 3K", "refseq_ac": [ { "id": "NP_001278393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278393", "type": "external" } ], "gene_names_uniprotkb": "TBC1D3K", "gene_names_refseq": "TBC1D3K", "protein_names_uniprotkb": "TBC1 domain family member 3K", "protein_names_refseq": "TBC1 domain family member 3K; TBC1 domain family member-like", "tax_id": 9606, "disease": "", "pathway": " (hsa:101060351)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21030649", "class_list": "", "function": "Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005768 endosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A087X1G2-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088BHA6-1", "uniprot_id": [ { "id": "A0A088BHA6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A088BHA6", "type": "external" } ], "mass": 16358.0, "length": 147, "protein_name": "Epidermal differentiation protein", "gene_name": "EDYM1", "organism": "Chicken", "refseq_name": "epidermal differentiation protein containing Y motif 1", "refseq_ac": [ { "id": "NP_001338368", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338368", "type": "external" } ], "gene_names_uniprotkb": "EDYM1", "gene_names_refseq": "EDYM1", "protein_names_uniprotkb": "Epidermal differentiation protein", "protein_names_refseq": "epidermal differentiation protein containing Y motif 1", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738218, SAMN02738221 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Dec 3, 2021 this sequence version replaced NP_001338368.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088BHA6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088BHA7-1", "uniprot_id": [ { "id": "A0A088BHA7_CHICK", "url": "https://www.uniprot.org/uniprot/A0A088BHA7", "type": "external" } ], "mass": 12175.0, "length": 99, "protein_name": "Epidermal differentiation protein; Potassium channel tetramerization domain containing 12A", "gene_name": "EDMTFH", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "EDMTFH; KCTD12A", "gene_names_refseq": "", "protein_names_uniprotkb": "Epidermal differentiation protein; Potassium channel tetramerization domain containing 12A", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088BHA7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088BHA8-1", "uniprot_id": [ { "id": "A0A088BHA8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A088BHA8", "type": "external" } ], "mass": 9152.0, "length": 86, "protein_name": "Epidermal differentiation protein; NK2 homeobox 3", "gene_name": "EDQM3", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "EDQM3; NKX2-3", "gene_names_refseq": "", "protein_names_uniprotkb": "Epidermal differentiation protein; NK2 homeobox 3", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088BHA8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088BHM9-1", "uniprot_id": [ { "id": "A0A088BHM9_CHICK", "url": "https://www.uniprot.org/uniprot/A0A088BHM9", "type": "external" } ], "mass": 34678.0, "length": 316, "protein_name": "Epidermal differentiation protein", "gene_name": "EDPE", "organism": "Chicken", "refseq_name": "protein TsetseEP-like", "refseq_ac": [ { "id": "NP_001306269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001306269", "type": "external" } ], "gene_names_uniprotkb": "EDPE; LOC107049024", "gene_names_refseq": "EDPE; LOC107049024", "protein_names_uniprotkb": "Epidermal differentiation protein", "protein_names_refseq": "epidermal differentiation protein rich in proline and glutamic acid (E); protein TsetseEP-like", "tax_id": 9031, "disease": "", "pathway": " (gga:107049024)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: ERR2365565.147682.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738217, SAMN02738218 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On May 11, 2017 this sequence version replaced XP_015153878.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088BHM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088BI16-1", "uniprot_id": [ { "id": "A0A088BI16_CHICK", "url": "https://www.uniprot.org/uniprot/A0A088BI16", "type": "external" } ], "mass": 23437.0, "length": 220, "protein_name": "Epidermal differentiation protein", "gene_name": "EDQCM", "organism": "Chicken", "refseq_name": "keratin-associated protein 9-1-like", "refseq_ac": [ { "id": "NP_001305926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305926", "type": "external" } ], "gene_names_uniprotkb": "EDQCM; LOC101751162", "gene_names_refseq": "EDQCM; LOC101751162", "protein_names_uniprotkb": "Epidermal differentiation protein", "protein_names_refseq": "epidermal differentiation protein containing QC motifs; keratin-associated protein 9-1-like", "tax_id": 9031, "disease": "", "pathway": " (gga:101751162)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On May 11, 2017 this sequence version replaced XP_004948297.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088BI16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088BID5-1", "uniprot_id": [ { "id": "A0A088BID5_CHICK", "url": "https://www.uniprot.org/uniprot/A0A088BID5", "type": "external" } ], "mass": 11170.0, "length": 99, "protein_name": "Epidermal differentiation protein", "gene_name": "EDCH3", "organism": "Chicken", "refseq_name": "epidermal differentiation protein containing cysteine histidine motifs 3", "refseq_ac": [ { "id": "NP_001338365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338365", "type": "external" } ], "gene_names_uniprotkb": "EDCH3", "gene_names_refseq": "EDCH3", "protein_names_uniprotkb": "Epidermal differentiation protein", "protein_names_refseq": "epidermal differentiation protein containing cysteine histidine motifs 3", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088BID5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088MLT8-1", "uniprot_id": [ { "id": "IQIP1_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A088MLT8", "type": "external" } ], "mass": 61917.0, "length": 559, "protein_name": "IQCJ-SCHIP1 readthrough transcript protein", "gene_name": "Iqcj-Schip1", "organism": "Mouse", "refseq_name": "IQCJ-SCHIP1 readthrough transcript protein", "refseq_ac": [ { "id": "NP_001106890", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106890", "type": "external" } ], "gene_names_uniprotkb": "Iqcj-Schip1; Iqschfp; Schip1", "gene_names_refseq": "Gm21949; Iqcj-schip1; Iqschfp; Schip-1-iqcj; Schip1", "protein_names_uniprotkb": "IQCJ-SCHIP1 readthrough transcript protein", "protein_names_refseq": "IQ motif containing J-schwannomin interacting protein 1 fusion protein; IQ motif containing J-schwannomin interacting protein 1 readthrough; IQCJ-SCHIP1 readthrough transcript protein", "tax_id": 10090, "disease": "", "pathway": " (mmu:100505386)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "18550753;25950943;25953347;27979964;34678516", "class_list": "", "function": "May play a role in action potential conduction in myelinated cells through the organization of molecular complexes at nodes of Ranvier and axon initial segments (PubMed:25950943, PubMed:25953347, PubMed:27979964). May also play a role in axon outgrowth and guidance (PubMed:25953347)., [UniProtKB, PubMed, PubMed, PubMed]; This locus represents naturally occurring read-through transcription from the neighboring IQ motif containing J (Iqcj) and schwannomin interacting protein 1 (Schip1) genes. This locus produces a transcript that is composed of in-frame exons from each individual gene. The resulting fusion protein is thought to be a component of the multimolecular complexes of axon initial segments and nodes of Ranvier, and it may play a role in calcium-mediated responses. [provided by RefSeq, Oct 2010]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8IJC6;A8IJD0;A8IJD3;F6YL02;F8WI70;Q3TI53;Q52KH1;Q6P9Y8;Q9CX07;Q9JLR0", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0044325 transmembrane transporter binding;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0033268 node of Ranvier;GO:0043194 axon initial segment", "go_biological_process": "GO:0051494 negative regulation of cytoskeleton organization;GO:0008366 axon ensheathment", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A088MLT8-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000000100000.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A088QMV3-1", "uniprot_id": [ { "id": "A0A088QMV3_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A088QMV3", "type": "external" } ], "mass": 34755.0, "length": 315, "protein_name": "17beta-estradiol 17-dehydrogenase", "gene_name": "hsd20b2", "organism": "Bovine", "refseq_name": "estradiol 17-beta-dehydrogenase 12-like", "refseq_ac": [ { "id": "NP_001231116", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231116", "type": "external" } ], "gene_names_uniprotkb": "hsd20b2; LOC508455", "gene_names_refseq": "LOC508455; hsd20b2", "protein_names_uniprotkb": "17beta-estradiol 17-dehydrogenase; 1.1.1.62", "protein_names_refseq": "20beta-hydroxysteroid dehydrogenase type 2; estradiol 17-beta-dehydrogenase 12-like", "tax_id": 9913, "disease": "", "pathway": " (bta:508455)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22061621", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006694 steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A088QMV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A089FKX6-1", "uniprot_id": [ { "id": "A0A089FKX6_CHICK", "url": "https://www.uniprot.org/uniprot/A0A089FKX6", "type": "external" } ], "mass": 37909.0, "length": 344, "protein_name": "MHC class I antigen; Major histocompatibility complex B, class I heavy chain BF2", "gene_name": "BF1", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BF1", "gene_names_refseq": "", "protein_names_uniprotkb": "MHC class I antigen; Major histocompatibility complex B, class I heavy chain BF2", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (R-GGA-1236974); (R-GGA-1236977); (R-GGA-163125); (R-GGA-198933); (R-GGA-6798695); (R-GGA-917977); (R-GGA-983170)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane;GO:0042612 MHC class I protein complex", "go_biological_process": "GO:0006955 immune response;GO:0002474 antigen processing and presentation of peptide antigen via MHC class I", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A089FKX6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A089N7J8-1", "uniprot_id": [ { "id": "A0A089N7J8_CHICK", "url": "https://www.uniprot.org/uniprot/A0A089N7J8", "type": "external" } ], "mass": 8525.0, "length": 83, "protein_name": "Epidermal differentiation protein; Keratin-associated protein 5-1-like", "gene_name": "EDMPN2", "organism": "Chicken", "refseq_name": "keratin-associated protein 5-1-like", "refseq_ac": [ { "id": "NP_001338363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338363", "type": "external" } ], "gene_names_uniprotkb": "EDMPN2", "gene_names_refseq": "EDMPN2", "protein_names_uniprotkb": "Epidermal differentiation protein; Keratin-associated protein 5-1-like", "protein_names_refseq": "epidermal differentiation protein containing a MPN sequence motif 2; keratin-associated protein 5-1-like", "tax_id": 9031, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "25169930", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A089N7J8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LNP1-1", "uniprot_id": [ { "id": "D131B_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LNP1", "type": "external" } ], "mass": 8156.0, "length": 70, "protein_name": "Beta-defensin 131B", "gene_name": "DEFB131B", "organism": "Human", "refseq_name": "beta-defensin 131B precursor", "refseq_ac": [ { "id": "NP_001229782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229782", "type": "external" } ], "gene_names_uniprotkb": "DEFB131B", "gene_names_refseq": "DEFB131B", "protein_names_uniprotkb": "Beta-defensin 131B; Defensin, beta 131", "protein_names_refseq": "beta-defensin 131B precursor; beta-defensin 131B; defensin, beta 131", "tax_id": 9606, "disease": "", "pathway": " (hsa:100129216)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has antibacterial activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096LNP1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LNW5-1", "uniprot_id": [ { "id": "NT2NR_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LNW5", "type": "external" } ], "mass": 30058.0, "length": 274, "protein_name": "Notch homolog 2 N-terminal-like protein R", "gene_name": "NOTCH2NLR", "organism": "Human", "refseq_name": "notch 2 N-terminal like R precursor", "refseq_ac": [ { "id": "NP_001383001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383001", "type": "external" } ], "gene_names_uniprotkb": "NOTCH2NLR", "gene_names_refseq": "NOTCH2NLD; NOTCH2NLR", "protein_names_uniprotkb": "Notch homolog 2 N-terminal-like protein R; NOTCH2NL-related", "protein_names_refseq": "notch 2 N-terminal like R (pseudogene); notch 2 N-terminal like R precursor; notch homolog 2 N-terminal-like-related", "tax_id": 9606, "disease": "intestinal cancer (Disease Ontology:DOID:10155); neurodegenerative disease (Disease Ontology:DOID:1289); brain cancer (Disease Ontology:DOID:1319); alcohol use disorder (Disease Ontology:DOID:1574); cancer (Disease Ontology:DOID:162); adenocarcinoma (Disease Ontology:DOID:299); central nervous system cancer (Disease Ontology:DOID:3620); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "11237011;29856954;29856955;31844290", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "", "go_biological_process": "GO:0048731 system development;GO:0009967 positive regulation of signal transduction;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A096LNW5-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LP01-1", "uniprot_id": [ { "id": "SIM26_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LP01", "type": "external" } ], "mass": 10908.0, "length": 95, "protein_name": "Small integral membrane protein 26", "gene_name": "SMIM26", "organism": "Human", "refseq_name": "small integral membrane protein 26 isoform 1", "refseq_ac": [ { "id": "NP_001335886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335886", "type": "external" } ], "gene_names_uniprotkb": "SMIM26; LINC00493", "gene_names_refseq": "LINC00493; SMIM26", "protein_names_uniprotkb": "Small integral membrane protein 26", "protein_names_refseq": "long intergenic non-protein coding RNA 493; small integral membrane protein 26 isoform 1", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 12, "publication_id_list": "11237011;26811146;28228285;30315122;31844290;32265295;32488085;32502341;33386847;33537174;34445188;37009826", "class_list": "", "function": "Identification and analysis of short open reading frames (sORFs) in the initially annotated noncoding RNA LINC00493 from human cells., [RefSeq, PubMed]; Investigation of LINC00493/SMIM26 Gene Suggests Its Dual Functioning at mRNA and Protein Level. Publication Status: Online-Only, [RefSeq, PubMed]; LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma., [RefSeq, PubMed]; May play a role in cell viability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A096LPB2", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A096LP01-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LP49-1", "uniprot_id": [ { "id": "CC187_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LP49", "type": "external" } ], "mass": 114856.0, "length": 1063, "protein_name": "Coiled-coil domain-containing protein 187", "gene_name": "CCDC187", "organism": "Human", "refseq_name": "coiled-coil domain-containing protein 187 isoform 1", "refseq_ac": [ { "id": "NP_001278445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278445", "type": "external" } ], "gene_names_uniprotkb": "CCDC187", "gene_names_refseq": "CCDC187", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 187", "protein_names_refseq": "coiled-coil domain-containing protein 187 isoform 1; coiled-coil domain-containing protein 187", "tax_id": 9606, "disease": "", "pathway": " (hsa:399693); (R-HSA-9013106)", "pathway_count": 2, "publication_count": 39, "publication_id_list": "11207612;11237011;12221096;15107133;16112081;16776779;16777452;16896804;17077126;17765681;17932950;18218625;19713215;20101212;20400958;21454492;21576392;21757538;22673745;22790947;22911862;22992742;23200924;23255595;24128008;25425145;26992070;27481945;31871319;33123756;33633747;35580925;7721814;8543060;8662891;8807639;8816443;8939998;9792683", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 8, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8N5P7", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005813 centrosome", "go_biological_process": "GO:0034453 microtubule anchoring", "synthesized_glycan_count": 0, "hit_score": 4.0, "record_id": "A0A096LP49-1", "record_type": "protein", "filter_code": "0000000.1000101.010000.0000000001000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LP55-1", "uniprot_id": [ { "id": "QCR6L_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LP55", "type": "external" } ], "mass": 10752.0, "length": 91, "protein_name": "Cytochrome b-c1 complex subunit 6-like, mitochondrial", "gene_name": "UQCRHL", "organism": "Human", "refseq_name": "cytochrome b-c1 complex subunit 6-like, mitochondrial", "refseq_ac": [ { "id": "NP_001083060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083060", "type": "external" } ], "gene_names_uniprotkb": "UQCRHL", "gene_names_refseq": "UQCRHL; hCG25371", "protein_names_uniprotkb": "Cytochrome b-c1 complex subunit 6-like, mitochondrial", "protein_names_refseq": "cytochrome b-c1 complex subunit 6-like, mitochondrial", "tax_id": 9606, "disease": "", "pathway": " (hsa:440567); (R-HSA-9865881)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "21278747;23168492;24385928;25008109;25605331;28380382;28673544;28844695;29243944;29493099;29557506;31611695;31844290;32350084;32929120;34357683;34969438", "class_list": "", "function": "May be a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1., [UniProtKB, UniProtKB]; This gene has characteristics of a pseudogene derived from the UQCRH gene. However, there is still an open reading frame that could produce a protein of the same or nearly the same size as that of the UQCRH gene, so this gene is being called protein-coding for now. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "A0A096LP55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LPG2-1", "uniprot_id": [ { "id": "A0A096LPG2_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LPG2", "type": "external" } ], "mass": 2704.0, "length": 23, "protein_name": "Uncharacterized protein", "gene_name": "", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096LPG2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096LPI5-1", "uniprot_id": [ { "id": "GVQW2_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A096LPI5", "type": "external" } ], "mass": 11989.0, "length": 108, "protein_name": "Putative uncharacterized protein CCDC28A-AS1", "gene_name": "CCDC28A-AS1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CCDC28A-AS1; GVQW2", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative uncharacterized protein CCDC28A-AS1; GVQW motif-containing protein 2", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"A0A096MJD8_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MJD8", "type": "external" } ], "mass": 53220.0, "length": 485, "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "organism": "Rat", "refseq_name": "SH2 domain-containing protein 5 isoform a", "refseq_ac": [ { "id": "NP_001418136", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418136", "type": "external" } ], "gene_names_uniprotkb": "Sh2d5", "gene_names_refseq": "RGD1305952; Sh2d5", "protein_names_uniprotkb": "SH2 domain-containing protein 5", "protein_names_refseq": "SH2 domain-containing protein 5 isoform a; SH2 domain-containing protein 5", "tax_id": 10116, "disease": "", "pathway": " (rno:366489)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25331951", "class_list": "", "function": "Data indicate that Src homology 2 domain containing protein 5 (SH2D5) controls neuronal morphology via breakpoint cluster region protein BCR and Rac1 GTP binding protein., [RefSeq, PubMed]; 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"type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0035556 intracellular signal transduction;GO:1902275 regulation of chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MJL4-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { 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Pro-apoptotic protein involved in LGR5-positive intestinal stem cell and Paneth cell expansion in the intestines, via its interaction with XIAP (By similarity). May also play a role in the regulation of cell fate in the intestine (By similarity). Positive regulator of apoptosis involved in hematopoietic stem cell homeostasis; via its interaction with XIAP (By similarity). Negative regulator of repair and hair follicle regeneration in response to injury, due to inhibition of hair follicle stem cell proliferation, potentially via its interaction with XIAP (By similarity). Plays an important role in male fertility and sperm motility (By similarity). During spermiogenesis, essential for the establishment of the annulus (a fibrous ring structure connecting the midpiece and the principal piece of the sperm flagellum) which is a requisite for the structural and mechanical integrity of the sperm (By similarity). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity). 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heart disease (Disease Ontology:DOID:114)", "pathway": " (R-RNO-3769402)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0090336 positive regulation of brown fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MJQ6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MJT6-1", "uniprot_id": [ { "id": "A0A096MJT6_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MJT6", "type": "external" } ], "mass": 556726.0, "length": 5027, "protein_name": "Bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "organism": "Rat", "refseq_name": "bridge-like lipid transfer protein family member 1", "refseq_ac": [ { "id": "NP_001358170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001358170", "type": "external" } ], "gene_names_uniprotkb": "Bltp1; 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Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. 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"https://www.uniprot.org/uniprot/A0A096MJY0", "type": "external" } ], "mass": 211676.0, "length": 1834, "protein_name": "Chromodomain helicase DNA binding protein 2", "gene_name": "Chd2", "organism": "Rat", "refseq_name": "chromodomain-helicase-DNA-binding protein 2", "refseq_ac": [ { "id": "NP_001100993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100993", "type": "external" } ], "gene_names_uniprotkb": "Chd2", "gene_names_refseq": "Chd2", "protein_names_uniprotkb": "Chromodomain helicase DNA binding protein 2", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 2", "tax_id": 10116, "disease": "CHARGE syndrome (Disease Ontology:DOID:0050834); autism spectrum disorder (Disease Ontology:DOID:0060041); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); developmental and epileptic encephalopathy 94 (Disease Ontology:DOID:0081325); prostate cancer (Disease Ontology:DOID:10283); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (rno:308738)", 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"url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424947", "type": "external" } ], "gene_names_uniprotkb": "Stoml3", "gene_names_refseq": "Stoml3", "protein_names_uniprotkb": "Stomatin like 3", "protein_names_refseq": "stomatin (Epb7.2)-like 3; stomatin-like protein 3", "tax_id": 10116, "disease": "nephrotic syndrome (Disease Ontology:DOID:1184)", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38073226", "class_list": "", "function": "Stomatin-like protein 3 modulates the responses of Adelta, but not C fiber bone afferent neurons to noxious mechanical stimulation in an animal model of acute experimental bone pain., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, 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factor 2C isoform 1; myocyte-specific enhancer factor 2C", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language (Disease Ontology:DOID:0070050); intellectual disability (Disease Ontology:DOID:1059); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); status epilepticus (Disease Ontology:DOID:1824); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (R-RNO-525793)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15862299;22673903;25287062;27427476;28473466", "class_list": "", "function": "In cardiomyocytes exposed to biomechanical stimulation, FAK accumulates in the nucleus, binds to and upregulates the transcriptional activity of MEF2c through an interaction with the FAK focal adhesion targeting (FAT) domain., [RefSeq, PubMed]; MEF2A and MEF2D were absolutely required for cardiomyocyte survival, whereas MEF2C, despite its major role in cardiac morphogenesis and direct reprogramming, was dispensable for this process., [RefSeq, PubMed]; Mef2c expression was sharply increased in compensating phase of right ventricular heart failure but lost in decompensation phase., [RefSeq, PubMed]; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes (PubMed:15862299). Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0003680 minor groove of adenine-thymine-rich DNA binding;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0098794 postsynapse", "go_biological_process": "GO:0002931 response to ischemia;GO:0071466 cellular response to xenobiotic stimulus;GO:0035050 embryonic heart tube development;GO:0010467 gene expression;GO:0097492 sympathetic neuron axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A096MJY4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000001.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MJY7-1", "uniprot_id": [ { "id": "A0A096MJY7_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MJY7", "type": "external" } ], "mass": 50606.0, "length": 463, "protein_name": "LSM14A mRNA processing body assembly factor", "gene_name": "Lsm14a", "organism": "Rat", "refseq_name": "protein LSM14 homolog A isoform 2", "refseq_ac": [ { "id": "NP_001425043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001425043", "type": "external" } ], "gene_names_uniprotkb": "Lsm14a", "gene_names_refseq": "Lsm14a; RGD1305695", "protein_names_uniprotkb": "LSM14A mRNA processing body assembly factor", "protein_names_refseq": "LSM14 homolog A; LSM14A, SCD6 homolog A; protein LSM14 homolog A isoform 2; protein LSM14 homolog A", "tax_id": 10116, "disease": "", "pathway": " (rno:361554)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003690 double-stranded DNA binding;GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex;GO:0072686 mitotic spindle", "go_biological_process": "GO:0051607 defense response to virus;GO:0090307 mitotic spindle assembly;GO:0017148 negative regulation of translation;GO:0033962 P-body assembly;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MJY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MJZ0-1", "uniprot_id": [ { "id": "DNAL1_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MJZ0", "type": "external" } ], "mass": 21503.0, "length": 190, "protein_name": "Dynein axonemal light chain 1", "gene_name": "Dnal1", "organism": "Rat", "refseq_name": "dynein axonemal light chain 1", "refseq_ac": [ { "id": "NP_001102947", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102947", "type": "external" } ], "gene_names_uniprotkb": "Dnal1", "gene_names_refseq": "Dnal1; Dnalc1; LC1", "protein_names_uniprotkb": "Dynein axonemal light chain 1; LC1", "protein_names_refseq": "axonemal dynein light chain 1; dynein axonemal light chain 1; dynein light chain 1, axonemal", "tax_id": 10116, "disease": "primary ciliary dyskinesia 16 (Disease Ontology:DOID:0110613)", "pathway": " (rno:685664)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21496787;22673903", "class_list": "", "function": "Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043014 alpha-tubulin binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0042995 cell projection;GO:0030286 dynein complex", "go_biological_process": "GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A096MJZ0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000001.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MJZ8-1", "uniprot_id": [ { "id": "A0A096MJZ8_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MJZ8", "type": "external" } ], "mass": 192027.0, "length": 1690, "protein_name": "Lysine-specific demethylase 5A", "gene_name": "Kdm5a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kdm5a", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysine-specific demethylase 5A; 1.14.11.67; Histone demethylase JARID1A; Jumonji/ARID domain-containing protein 1A; Retinoblastoma-binding protein 2; [histone H3]-trimethyl-L-lysine(4) demethylase 5A", "protein_names_refseq": "", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); autism spectrum disorder (Disease Ontology:DOID:0060041); syndromic X-linked intellectual disability Claes-Jensen type (Disease Ontology:DOID:0060809); prostate cancer (Disease Ontology:DOID:10283); intellectual disability (Disease Ontology:DOID:1059); cryptorchidism (Disease Ontology:DOID:11383); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); lung non-small cell carcinoma (Disease Ontology:DOID:3908); stomach carcinoma (Disease Ontology:DOID:5517); ankylosing spondylitis (Disease Ontology:DOID:7147); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (R-RNO-3214842)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.67", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.67", "type": "external" } ], "go_molecular_function": "GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0032453 histone H3K4 demethylase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0032993 protein-DNA complex;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0008584 male gonad development;GO:0045893 positive regulation of DNA-templated transcription;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MJZ8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK02-1", "uniprot_id": [ { "id": "A0A096MK02_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK02", "type": "external" } ], "mass": 45159.0, "length": 405, "protein_name": "Opticin", "gene_name": "Optc", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Optc", "gene_names_refseq": "", "protein_names_uniprotkb": "Opticin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1474228)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", 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"biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0001525 angiogenesis;GO:0030199 collagen fibril organization;GO:0016525 negative regulation of angiogenesis;GO:0060348 bone development;GO:0061975 articular cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK02-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK07-1", "uniprot_id": [ { "id": "A0A096MK07_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK07", "type": "external" } ], "mass": 140254.0, "length": 1247, "protein_name": "Uncharacterized protein", "gene_name": "AC118772.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AC118772.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043022 ribosome binding;GO:0004521 RNA endonuclease activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0006402 mRNA catabolic process;GO:0016075 rRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK07-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK19-1", "uniprot_id": [ { "id": "A0A096MK19_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK19", "type": "external" } ], "mass": 48447.0, "length": 421, "protein_name": "mRNA-decapping enzyme 2", "gene_name": "Dcp2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dcp2", "gene_names_refseq": "", "protein_names_uniprotkb": "mRNA-decapping enzyme 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-430039); (R-RNO-450385); (R-RNO-450513); (R-RNO-450604)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. The presence of a N(6)-methyladenosine methylation at the second transcribed position of mRNAs (N(6),2'-O-dimethyladenosine cap; m6A(m)) provides resistance to DCP2-mediated decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.1.13.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.4", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" }, { "id": "3.6.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.59", "type": "external" }, { "id": "3.6.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.52", "type": "external" }, { "id": "3.6.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.10", "type": "external" }, { "id": "3.6.1.61", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.61", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004534 5'-3' RNA exonuclease activity;GO:0070034 telomerase RNA binding;GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000932 P-body;GO:0016442 RISC complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043488 regulation of mRNA stability;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0006402 mRNA catabolic process;GO:0071044 histone mRNA catabolic process;GO:1904872 regulation of telomerase RNA localization to Cajal body", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MK19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK39-1", "uniprot_id": [ { "id": "A0A096MK39_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK39", "type": "external" } ], "mass": 52857.0, "length": 489, "protein_name": "Heat shock transcription factor 4", "gene_name": "Hsf4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Hsf4", "gene_names_refseq": "", "protein_names_uniprotkb": "Heat shock transcription factor 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "cataract 5 multiple types (Disease Ontology:DOID:0110255); neurodegenerative disease (Disease Ontology:DOID:1289); cataract (Disease Ontology:DOID:83)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0016607 nuclear speck", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK39-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK47-4", "uniprot_id": [ { "id": "MLIP_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK47", "type": "external" } ], "mass": 103653.0, "length": 966, "protein_name": "Muscular LMNA-interacting protein", "gene_name": "Mlip", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mlip; Cip", "gene_names_refseq": "", "protein_names_uniprotkb": "Muscular LMNA-interacting protein; CIP; Cardiac Isl1-interacting protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "22343712;22673903;26436652", "class_list": "", "function": "Required for myoblast differentiation into myotubes, possibly acting as a transcriptional regulator of the myogenic program (By similarity). Required for cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays a role in the protection against cardiac hypertrophy (PubMed:22343712, PubMed:26436652). Binds chromatin (By similarity). May act as a transcriptional cofactor for ISL1, repressing its transcriptional activity (By similarity). May also repress MYOCD transcriptional activity (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8I6ARD4;D4A3C4;Q569A0", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0005521 lamin binding", "go_cellular_component": "GO:0031981 nuclear lumen;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005829 cytosol;GO:0042383 sarcolemma", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress;GO:0010614 negative regulation of cardiac muscle hypertrophy", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A096MK47-4", "record_type": "protein", "filter_code": "0000000.0000100.010000.0000000000001000.0000000001001.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK48-1", "uniprot_id": [ { "id": "A0A096MK48_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK48", "type": "external" } ], "mass": 17544.0, "length": 160, "protein_name": "Small EDRK-rich factor 1", "gene_name": "Serf1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Serf1", "gene_names_refseq": "", "protein_names_uniprotkb": "Small EDRK-rich factor 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:1990000 amyloid fibril formation;GO:0031648 protein destabilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK48-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK49-1", "uniprot_id": [ { "id": "A0A096MK49_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK49", "type": "external" } ], "mass": 56933.0, "length": 514, "protein_name": "Importin subunit alpha", "gene_name": "Kpna7", "organism": "Rat", "refseq_name": "importin subunit alpha-8", "refseq_ac": [ { "id": "XP_063127993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063127993", "type": "external" } ], "gene_names_uniprotkb": "Kpna7", "gene_names_refseq": "Kpna7", "protein_names_uniprotkb": "Importin subunit alpha", "protein_names_refseq": "importin subunit alpha-8", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions in nuclear protein import., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008139 nuclear localization sequence binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0001674 female germ cell nucleus;GO:0042564 NLS-dependent protein nuclear import complex", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0040029 epigenetic regulation of gene expression;GO:0001824 blastocyst development;GO:0006607 NLS-bearing protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK49-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK60-1", "uniprot_id": [ { "id": "A0A096MK60_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK60", "type": "external" } ], "mass": 107429.0, "length": 940, "protein_name": "Schlafen family member 5", "gene_name": "Slfn5", "organism": "Rat", "refseq_name": "schlafen family member 5 isoform 1", "refseq_ac": [ { "id": "NP_001417117", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417117", "type": "external" } ], "gene_names_uniprotkb": "Slfn5", "gene_names_refseq": "Slfn5", "protein_names_uniprotkb": "Schlafen family member 5", "protein_names_refseq": "schlafen 5; schlafen family member 5 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:303377)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MK60-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK61-1", "uniprot_id": [ { "id": "A0A096MK61_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK61", "type": "external" } ], "mass": 46491.0, "length": 403, "protein_name": "Cartilage associated protein", "gene_name": "Crtap", "organism": "Rat", "refseq_name": "cartilage-associated protein isoform 1 precursor", "refseq_ac": [ { "id": "NP_001388132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388132", "type": "external" } ], "gene_names_uniprotkb": "Crtap; Crtapl1; LOC102555086", "gene_names_refseq": "Crtapl1; Crtap; RGD1565180", "protein_names_uniprotkb": "Cartilage associated protein", "protein_names_refseq": "cartilage associated protein-like 1; cartilage-associated protein isoform 1 precursor; cartilage-associated protein-like", "tax_id": 10116, "disease": "osteogenesis imperfecta type 7 (Disease Ontology:DOID:0110337)", "pathway": " (R-RNO-1650814)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:1901874 negative regulation of post-translational protein modification;GO:0007283 spermatogenesis;GO:0030199 collagen fibril organization;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK61-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK67-1", "uniprot_id": [ { "id": "A0A096MK67_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK67", "type": "external" } ], "mass": 95734.0, "length": 847, "protein_name": "Follistatin-related protein 5", "gene_name": "Fstl5", "organism": "Rat", "refseq_name": "follistatin-related protein 5 isoform X2", "refseq_ac": [ { "id": "XP_017446483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017446483", "type": "external" } ], "gene_names_uniprotkb": "Fstl5", "gene_names_refseq": "Fstl5", "protein_names_uniprotkb": "Follistatin-related protein 5; Follistatin-like protein 5", "protein_names_refseq": "follistatin-related protein 5 isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0030154 cell differentiation;GO:0030510 regulation of BMP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK67-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK69-1", "uniprot_id": [ { "id": "A0A096MK69_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK69", "type": "external" } ], "mass": 34487.0, "length": 308, "protein_name": "Olfactory receptor family 8 subfamily B member 37", "gene_name": "Or8b37", "organism": "Rat", "refseq_name": "olfactory receptor Olr1206", "refseq_ac": [ { "id": "NP_001000816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000816", "type": "external" } ], "gene_names_uniprotkb": "Or8b37", "gene_names_refseq": "Olr1206; Or8b37", "protein_names_uniprotkb": "Olfactory receptor family 8 subfamily B member 37", "protein_names_refseq": "olfactory receptor 1206; olfactory receptor Olr1206; olfactory receptor gene Olr1206", "tax_id": 10116, "disease": "", "pathway": " (rno:405103)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK69-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK85-1", "uniprot_id": [ { "id": "A0A096MK85_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK85", "type": "external" } ], "mass": 32126.0, "length": 303, "protein_name": "Sushi domain containing 6", "gene_name": "Susd6", "organism": "Rat", "refseq_name": "sushi domain-containing protein 6 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001385859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385859", "type": "external" } ], "gene_names_uniprotkb": "Susd6; LOC678893", "gene_names_refseq": "Susd6", "protein_names_uniprotkb": "Sushi domain containing 6", "protein_names_refseq": "sushi domain-containing protein 6 isoform 2 precursor; sushi domain-containing protein 6", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MK85-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK89-1", "uniprot_id": [ { "id": "A0A096MK89_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK89", "type": "external" } ], "mass": 685897.0, "length": 6298, "protein_name": "Adhesion G-protein coupled receptor V1", "gene_name": "Adgrv1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Adgrv1", "gene_names_refseq": "", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor V1; G-protein coupled receptor 98; Very large G-protein coupled receptor 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Usher syndrome type 2C (Disease Ontology:DOID:0110839); familial febrile seizures 4 (Disease Ontology:DOID:0111305); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cleaved ADGRV1 beta-subunit couples with G-alpha(i)-proteins, GNAI1/2/3, and constitutively inhibits adenylate cyclase (AC) activity with a stronger effect than full ADGRV1., [UniProtKB, UniProtKB]; G-protein coupled receptor which has an essential role in the development of hearing and vision. Couples to G-alpha(i)-proteins, GNAI1/2/3, G-alpha(q)-proteins, GNAQ, as well as G-alpha(s)-proteins, GNAS, inhibiting adenylate cyclase (AC) activity and cAMP production. Required for the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells of the inner ear. In response to extracellular calcium, activates kinases PKA and PKC to regulate myelination by inhibiting the ubiquitination of MAG, thus enhancing the stability of this protein in myelin-forming cells of the auditory pathway. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport. Involved in the regulation of bone metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0016787 hydrolase activity;GO:0005509 calcium ion binding;GO:0017022 myosin binding;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0048496 maintenance of animal organ identity;GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0050877 nervous system process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK89-1", "record_type": "protein", "filter_code": "0000000.1000010.000100.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MK92-1", "uniprot_id": [ { "id": "A0A096MK92_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MK92", "type": "external" } ], "mass": 93055.0, "length": 825, "protein_name": "Intraflagellar transport 88", "gene_name": "Ift88", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ift88", "gene_names_refseq": "", "protein_names_uniprotkb": "Intraflagellar transport 88", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); silicosis (Disease Ontology:DOID:10325); scimitar syndrome (Disease Ontology:DOID:4297); mitral valve disease (Disease Ontology:DOID:61); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005929 cilium;GO:0031514 motile cilium", "go_biological_process": "GO:0021513 spinal cord dorsal/ventral patterning;GO:0034021 response to silicon dioxide;GO:0001889 liver development;GO:0007219 Notch signaling pathway;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK92-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKA9-1", "uniprot_id": [ { "id": "A0A096MKA9_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKA9", "type": "external" } ], "mass": 94923.0, "length": 827, "protein_name": "Toll-like receptor", "gene_name": "Tlr6", "organism": "Rat", "refseq_name": "toll-like receptor 6", "refseq_ac": [ { "id": "NP_001424145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424145", "type": "external" } ], "gene_names_uniprotkb": "Tlr6", "gene_names_refseq": "Tlr6", "protein_names_uniprotkb": "Toll-like receptor", "protein_names_refseq": "toll-like receptor 6", "tax_id": 10116, "disease": "infective endocarditis (Disease Ontology:DOID:0060000); aspergillosis (Disease Ontology:DOID:13564); alcohol use disorder (Disease Ontology:DOID:1574); asthma (Disease Ontology:DOID:2841); tuberculosis (Disease Ontology:DOID:399); glucose metabolism disease (Disease Ontology:DOID:4194); rhinitis (Disease Ontology:DOID:4483); primary immunodeficiency disease (Disease Ontology:DOID:612); collagen disease (Disease Ontology:DOID:854); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); bacterial pneumonia (Disease Ontology:DOID:874)", "pathway": " (R-RNO-5686938)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0071723 lipopeptide binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0030670 phagocytic vesicle membrane;GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex", "go_biological_process": "GO:0046209 nitric oxide metabolic process;GO:0043032 positive regulation of macrophage activation;GO:0034136 negative regulation of toll-like receptor 2 signaling pathway;GO:0042496 detection of diacyl bacterial lipopeptide;GO:0001774 microglial cell activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKA9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKB0-1", "uniprot_id": [ { "id": "A0A096MKB0_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKB0", "type": "external" } ], "mass": 27314.0, "length": 242, "protein_name": "Ras-related protein Rab-24", "gene_name": "Rab24", "organism": "Rat", "refseq_name": "ras-related protein Rab-24", "refseq_ac": [ { "id": "NP_001015023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015023", "type": "external" } ], "gene_names_uniprotkb": "Rab24", "gene_names_refseq": "Rab24", "protein_names_uniprotkb": "Ras-related protein Rab-24; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-24", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16236257", "class_list": "", "function": "Expression of Rab24 mRNA was also induced in differentiated PC12 cells following proteasome inhibitor, [RefSeq, PubMed]; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB24 is an atypical RAB protein that presents low GTPase activity and thereby exists predominantly in the GTP-bound active state. RAB24 is required for the clearance of late autophagic vacuoles under basal conditions. It is not needed for starvation-induced autophagy. Involved in the modulation of meiotic apparatus assembly and meiotic progression during oocyte maturation, possibly through regulation of kinetochore-microtubule interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0005776 autophagosome", "go_biological_process": "GO:0015031 protein transport;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MKB0-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKC0-1", "uniprot_id": [ { "id": "A0A096MKC0_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKC0", "type": "external" } ], "mass": 151284.0, "length": 1307, "protein_name": "GRB10 interacting GYF protein 2", "gene_name": "Gigyf2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gigyf2", "gene_names_refseq": "", "protein_names_uniprotkb": "GRB10 interacting GYF protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); Parkinson's disease (Disease Ontology:DOID:14330); schizophrenia (Disease Ontology:DOID:5419)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0070064 proline-rich region binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0008344 adult locomotory behavior;GO:0050881 musculoskeletal movement;GO:0050885 neuromuscular process controlling balance;GO:0035264 multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MKC0-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKC4-1", "uniprot_id": [ { "id": "A0A096MKC4_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKC4", "type": "external" } ], "mass": 87018.0, "length": 755, "protein_name": "Transmembrane channel-like protein", "gene_name": "Tmc1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tmc1", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane channel-like protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 7 (Disease Ontology:DOID:0110520); autosomal dominant nonsyndromic deafness 36 (Disease Ontology:DOID:0110563); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0008381 mechanosensitive monoatomic ion channel activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0032426 stereocilium tip;GO:0032420 stereocilium", "go_biological_process": "GO:0060005 vestibular reflex;GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0007605 sensory perception of sound;GO:0070588 calcium ion transmembrane transport;GO:1903169 regulation of calcium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKC4-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKC6-1", "uniprot_id": [ { "id": "A0A096MKC6_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKC6", "type": "external" } ], "mass": 20918.0, "length": 181, "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "Mup4-ps8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mup4-ps8", "gene_names_refseq": "", "protein_names_uniprotkb": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0036094 small molecule binding;GO:0005550 pheromone binding;GO:0005549 odorant binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKC6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKD1-1", "uniprot_id": [ { "id": "A0A096MKD1_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKD1", "type": "external" } ], "mass": 27850.0, "length": 244, "protein_name": "EEF1A lysine methyltransferase 1", "gene_name": "Eef1akmt1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Eef1akmt1; EEF1AKMT1; N6AMT2; N6amt2", "gene_names_refseq": "", "protein_names_uniprotkb": "EEF1A lysine methyltransferase 1; 2.1.1.-; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase N6AMT2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8876725)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0008168 methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKD1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKD8-1", "uniprot_id": [ { "id": "A0A096MKD8_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKD8", "type": "external" } ], "mass": 58145.0, "length": 518, "protein_name": "Unc-5 family C-terminal like", "gene_name": "Unc5cl", "organism": "Rat", "refseq_name": "UNC5C-like protein isoform 1", "refseq_ac": [ { "id": "NP_001100352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100352", "type": "external" } ], "gene_names_uniprotkb": "Unc5cl", "gene_names_refseq": "Unc5cl", "protein_names_uniprotkb": "Unc-5 family C-terminal like", "protein_names_refseq": "UNC5C-like protein isoform 1; UNC5C-like protein; unc-5 homolog C-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008233 peptidase activity;GO:0005042 netrin receptor activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0046330 positive regulation of JNK cascade;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKD8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKE9-1", "uniprot_id": [ { "id": "A0A096MKE9_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKE9", "type": "external" } ], "mass": 109112.0, "length": 976, "protein_name": "DNA ligase", "gene_name": "Lig3", "organism": "Rat", "refseq_name": "DNA ligase 3 isoform X4", "refseq_ac": [ { "id": "XP_008766243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766243", "type": "external" } ], "gene_names_uniprotkb": "Lig3", "gene_names_refseq": "Lig3", "protein_names_uniprotkb": "DNA ligase; 6.5.1.1", "protein_names_refseq": "DNA ligase 3 isoform X4", "tax_id": 10116, "disease": "mitochondrial DNA depletion syndrome 20 (Disease Ontology:DOID:0070451); pancreatic cancer (Disease Ontology:DOID:1793); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (R-RNO-110381); (R-RNO-5649702); (R-RNO-5685939); (R-RNO-6782210)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "3.1.3.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0003909 DNA ligase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0000795 synaptonemal complex;GO:0005634 nucleus", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0097681 double-strand break repair via alternative nonhomologous end joining;GO:0006310 DNA recombination;GO:0051301 cell division;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MKE9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKF8-1", "uniprot_id": [ { "id": "A0A096MKF8_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKF8", "type": "external" } ], "mass": 244538.0, "length": 2190, "protein_name": "Mediator complex subunit 12", "gene_name": "Med12", "organism": "Rat", "refseq_name": "mediator of RNA polymerase II transcription subunit 12 isoform 1", "refseq_ac": [ { "id": "NP_001401664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401664", "type": "external" } ], "gene_names_uniprotkb": "Med12", "gene_names_refseq": "Med12", "protein_names_uniprotkb": "Mediator complex subunit 12", "protein_names_refseq": "mediator of RNA polymerase II transcription subunit 12 isoform 1; mediator of RNA polymerase II transcription subunit 12", "tax_id": 10116, "disease": "syndromic X-linked intellectual disorder Lujan-Fryns-type (Disease Ontology:DOID:0080985); major depressive disorder (Disease Ontology:DOID:1470); FG syndrome (Disease Ontology:DOID:14711); leiomyosarcoma (Disease Ontology:DOID:1967); phobic disorder (Disease Ontology:DOID:591); obesity (Disease Ontology:DOID:9970)", "pathway": " (R-RNO-9841922)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0008013 beta-catenin binding;GO:0046966 nuclear thyroid hormone receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000151 ubiquitin ligase complex;GO:0016592 mediator complex;GO:1990508 CKM complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0007507 heart development;GO:0021510 spinal cord development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MKF8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKF9-1", "uniprot_id": [ { "id": "A0A096MKF9_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKF9", "type": "external" } ], "mass": 68984.0, "length": 621, "protein_name": "Complement C2", "gene_name": "C2; Cfb", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "C2; Cfb; C2; Cfb", "gene_names_refseq": "", "protein_names_uniprotkb": "Complement C2; C3/C5 convertase", "protein_names_refseq": "", "tax_id": 10116, "disease": "sinusitis (Disease Ontology:DOID:0050127); complement component 2 deficiency (Disease Ontology:DOID:0060295); lupus nephritis (Disease Ontology:DOID:0080162); atypical hemolytic-uremic syndrome (Disease Ontology:DOID:0080301); polycystic kidney disease (Disease Ontology:DOID:0080322); erythema nodosum (Disease Ontology:DOID:0080750); age related macular degeneration 14 (Disease Ontology:DOID:0110026); autosomal dominant Alport syndrome (Disease Ontology:DOID:0110032); autosomal recessive Alport syndrome (Disease Ontology:DOID:0110033); benign familial hematuria (Disease Ontology:DOID:0111365); Alzheimer's disease (Disease Ontology:DOID:10652); lepromatous leprosy (Disease Ontology:DOID:10887); sickle cell anemia (Disease Ontology:DOID:10923); membranous glomerulonephritis (Disease Ontology:DOID:10976); Alport syndrome (Disease Ontology:DOID:10983); pyelonephritis (Disease Ontology:DOID:11400); factor VIII deficiency (Disease Ontology:DOID:12134); beta thalassemia (Disease Ontology:DOID:12241); paracoccidioidomycosis (Disease Ontology:DOID:12662); Behcet's disease (Disease Ontology:DOID:13241); anterior uveitis (Disease Ontology:DOID:1407); boutonneuse fever (Disease Ontology:DOID:14095); breast cancer (Disease Ontology:DOID:1612); membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); glomerulonephritis (Disease Ontology:DOID:2921); IgA glomerulonephritis (Disease Ontology:DOID:2986); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); conjunctivitis (Disease Ontology:DOID:6195); end stage renal disease (Disease Ontology:DOID:783); retinal degeneration (Disease Ontology:DOID:8466); psoriasis (Disease Ontology:DOID:8893); diabetic retinopathy (Disease Ontology:DOID:8947); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); systemic lupus erythematosus (Disease Ontology:DOID:9074); type 1 diabetes mellitus (Disease Ontology:DOID:9744); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:294257); (R-RNO-166663); (R-RNO-174577); (R-RNO-977606)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic component of the complement C3 and C5 convertase complexes. Following complement activation, recruited to the surface of pathogens by complement C4b opsonin to form the C3 convertase, or C3b and C4b opsonins to form the C5 convertase. As part of the C3 convertase, cleaves and activate C3 into C3a anaphylatoxin and C3b opsonin, the next components of the complement pathways. As part of the C5 convertase, cleaves and activate C5 into C5a anaphylatoxin and C5b component of the membrane attack complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Involved in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes., [UniProtKB, UniProtKB]; Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases., [UniProtKB, UniProtKB]; Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Serine protease component of the complement C3 and C5 convertase complexes of the alternative complement pathway. Following cleavage and activation by factor D (CFD), forms the C3 convertase together with complement C3b. As part of the C3 convertase, cleaves and activates C3 into C3a anaphylatoxin and C3b opsonin, the next components of the complement pathways. When an additional complement C3b molecule binds to the C3 convertase, forms the C5 convertase, which cleaves and activates C5 into C5a anaphylatoxin and C5b component of the membrane attack complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0007584 response to nutrient;GO:0032496 response to lipopolysaccharide;GO:0097066 response to thyroid hormone;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKF9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKH2-1", "uniprot_id": [ { "id": "A0A096MKH2_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKH2", "type": "external" } ], "mass": 33975.0, "length": 309, "protein_name": "Vesicle trafficking 1", "gene_name": "Vta1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Vta1; 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RGD1562967", "protein_names_uniprotkb": "Multiple C2 and transmembrane domain-containing protein 2", "protein_names_refseq": "multiple C2 and transmembrane domain-containing protein 2; multiple C2 domains, transmembrane 2", "tax_id": 10116, "disease": "", "pathway": " (rno:308742)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Might play a role in the development of cardiac outflow tract., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0030672 synaptic vesicle membrane;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046928 regulation of neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MKH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKI0-1", "uniprot_id": [ { "id": "A0A096MKI0_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKI0", "type": "external" } ], "mass": 109596.0, "length": 992, "protein_name": "Adhesion G protein-coupled receptor F3", "gene_name": "Adgrf3", "organism": "Rat", "refseq_name": "adhesion G-protein coupled receptor F3 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001401841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401841", "type": "external" } ], "gene_names_uniprotkb": "Adgrf3", "gene_names_refseq": "Adgrf3; Gpr113", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor F3", "protein_names_refseq": "G protein-coupled receptor 113; adhesion G-protein coupled receptor F3 isoform 1 precursor; probable G-protein coupled receptor 113", "tax_id": 10116, "disease": "", "pathway": " (rno:298857)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKI0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.0000000000001000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096P6M5-1", "uniprot_id": [ { "id": "A0A096P6M5_RAT", "url": "https://www.uniprot.org/uniprot/A0A096P6M5", "type": "external" } ], "mass": 35636.0, "length": 312, "protein_name": "Olfactory receptor family 1 subfamily E member 35B", "gene_name": "Or1e35b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1504", "refseq_ac": [ { "id": "NP_001000495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000495", "type": "external" } ], "gene_names_uniprotkb": "Or1e35b", "gene_names_refseq": "Olr1504; Or1e35b", "protein_names_uniprotkb": "Olfactory receptor family 1 subfamily E member 35B", "protein_names_refseq": "olfactory receptor 1504; olfactory receptor Olr1504; olfactory receptor gene Olr1504", "tax_id": 10116, "disease": "", "pathway": " (rno:303296)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096P6M5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096UWG1-1", "uniprot_id": [ { "id": "A0A096UWG1_RAT", "url": "https://www.uniprot.org/uniprot/A0A096UWG1", "type": "external" } ], "mass": 80394.0, "length": 733, "protein_name": "COP1, E3 ubiquitin ligase", "gene_name": "Cop1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cop1; RGD1304773; Rfwd2", "gene_names_refseq": "", "protein_names_uniprotkb": "COP1, E3 ubiquitin ligase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:360860); (R-RNO-349425); (R-RNO-8951664)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0000139 Golgi membrane;GO:0005634 nucleus", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010212 response to ionizing radiation;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096UWG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096UWG9-1", "uniprot_id": [ { "id": "A0A096UWG9_RAT", "url": "https://www.uniprot.org/uniprot/A0A096UWG9", "type": "external" } ], "mass": 63960.0, "length": 567, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgke", "organism": "Rat", "refseq_name": "diacylglycerol kinase epsilon isoform 1", "refseq_ac": [ { "id": "NP_001381287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381287", "type": "external" } ], "gene_names_uniprotkb": "Dgke", "gene_names_refseq": "Dgke", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase epsilon isoform 1; diacylglycerol kinase, epsilon 64kDa", "tax_id": 10116, "disease": "nephrotic syndrome type 7 (Disease Ontology:DOID:0080388)", "pathway": " (R-RNO-114508)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "18487437;19421779;23467923;28191598", "class_list": "", "function": "DGKepsilon interacts with actin stress fibers and is involved in their stability in vascular smooth muscle cells., [RefSeq, PubMed]; Diacylglycerol kinase-epsilon restores cardiac dysfunction under chronic pressure overload: a new specific regulator of Galpha(q) signaling cascade., [RefSeq, PubMed]; Findings suggest that DGKepsilon plays an important role in neuronal and brain functions through its distinct neuronal expression and subcellular localization and also through coordinated arrangement with other molecules involving the phosphoinositide signaling pathway, [RefSeq, PubMed]; Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle. Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently., [UniProtKB, UniProtKB]; The DGKepsilon is evident in the outer limiting membrane., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" }, { "id": "2.7.1.93", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.93", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A096UWG9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096X8J7-1", "uniprot_id": [ { "id": "B3A3_DANRE", "url": "https://www.uniprot.org/uniprot/A0A096X8J7", "type": "external" } ], "mass": 132420.0, "length": 1170, "protein_name": "Anion exchange protein 3", "gene_name": "Slc4a3; slc4a3", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc4a3; slc4a3; AE 3; Ae3", "gene_names_refseq": "", "protein_names_uniprotkb": "Anion exchange protein 3; AE 3; Solute carrier family 4 member 3", "protein_names_refseq": "", "tax_id": 7955, "disease": "short QT syndrome (Disease Ontology:DOID:0050793); anemia (Disease Ontology:DOID:2355)", "pathway": " (dre:100333073); (R-DRE-425381)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "23594743;24668450;27189481;29167417;36806574", "class_list": "", "function": "Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (By similarity). May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential (PubMed:29167417)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0008509 monoatomic anion transmembrane transporter activity;GO:0005452 solute:inorganic anion antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015701 bicarbonate transport;GO:0051453 regulation of intracellular pH;GO:0086001 cardiac muscle cell action potential", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A096X8J7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A097-1", "uniprot_id": [ { "id": "A0A097_DANRE", "url": "https://www.uniprot.org/uniprot/A0A097", "type": "external" } ], "mass": 5192.0, "length": 46, "protein_name": "Thymosin beta", "gene_name": "tmsb1", "organism": "Zebrafish", "refseq_name": "thymosin beta 1", "refseq_ac": [ { "id": "NP_001159390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159390", "type": "external" } ], "gene_names_uniprotkb": "tmsb1; Tbeta-a; fb15g10; si:dkey-152p16.6; tbeta-a; wu:fb15g10", "gene_names_refseq": "fb15g10; si:dkey-152p16.6; tbeta-a; tmsb1; wu:fb15g10", "protein_names_uniprotkb": "Thymosin beta", "protein_names_refseq": "beta thymosin-like protein 2; thymosin beta 1; thymosin beta-a; zTB1", "tax_id": 7955, "disease": "", "pathway": " (dre:798430)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "20138884;23594743;24732964;25596145;26487724;27189481;33945241;36291156;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH506469.1, EH503104.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH532625.1, EH506469.1 and BC142834.1., [RefSeq]; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C7G093", "ec_number_list": [], "go_molecular_function": "GO:0003785 actin monomer binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005856 cytoskeleton", "go_biological_process": "GO:0007015 actin filament organization;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A097-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0100000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A097HUX0-1", "uniprot_id": [ { "id": "A0A097HUX0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A097HUX0", "type": "external" } ], "mass": 57810.0, "length": 505, "protein_name": "1.14.15.18; 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; 25-hydroxyvitamin D-1alpha-hydroxylase", "gene_name": "cyp27b1", "organism": "Zebrafish", "refseq_name": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "refseq_ac": [ { "id": "NP_001298720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001298720", "type": "external" } ], "gene_names_uniprotkb": "cyp27b1", "gene_names_refseq": "cyp27b1", "protein_names_uniprotkb": "1.14.15.18; 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; 25-hydroxyvitamin D-1alpha-hydroxylase", "protein_names_refseq": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; 25-hydroxyvitamin D-1alpha-hydroxylase", "tax_id": 7955, "disease": "vitamin D-dependent rickets type 1A (Disease Ontology:DOID:0080886); pre-eclampsia (Disease Ontology:DOID:10591); rickets (Disease Ontology:DOID:10609); gestational diabetes (Disease Ontology:DOID:11714); hepatitis B (Disease Ontology:DOID:2043); nephrosis (Disease Ontology:DOID:2527); acute kidney failure (Disease Ontology:DOID:3021); Wilson disease (Disease Ontology:DOID:893); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:793309); (R-DRE-196791); (R-DRE-211916)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "21887296;23029160;23594743;25290078;26469318;27705794;32004617;32994480;33396133;35474468;36864841", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: KM262796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KM262796.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Loss of Cyp27b1-mediated biosynthesis or vitamin D receptor (VDR) function by gene knockdown resulted in significantly reduced runx1 expression and Flk1(+)cMyb(+) HSPC numbers., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.15.18", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.18", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004498 calcidiol 1-monooxygenase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0071425 hematopoietic stem cell proliferation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A097HUX0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A097ZPG7-1", "uniprot_id": [ { "id": "A0A097ZPG7_DANRE", "url": "https://www.uniprot.org/uniprot/A0A097ZPG7", "type": "external" } ], "mass": 22623.0, "length": 191, "protein_name": "Methyl-CpG-binding domain protein 4", "gene_name": "mbd4", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mbd4; MBD4", "gene_names_refseq": "", "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 4; Methyl-CpG-binding protein MBD4; Mismatch-specific DNA N-glycosylase", "protein_names_refseq": "", "tax_id": 7955, "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); lung cancer (Disease Ontology:DOID:1324); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); uveal melanoma (Disease Ontology:DOID:6039); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (dre:101887128)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;25536520", "class_list": "", "function": "Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z033", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A097ZPG7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KX95-1", "uniprot_id": [ { "id": "A0A098KX95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KX95", "type": "external" } ], "mass": 31817.0, "length": 284, "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "gene_name": "Agpat1", "organism": "Hamster", "refseq_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "refseq_ac": [ { "id": "XP_003508512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508512", "type": "external" } ], "gene_names_uniprotkb": "Agpat1; H671_1g3844", "gene_names_refseq": "Agpat1", "protein_names_uniprotkb": "1-acyl-sn-glycerol-3-phosphate acyltransferase; 2.3.1.51", "protein_names_refseq": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100758206)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 286 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614548.1) and transcript sequence (IACG01092654.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0001819 positive regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KX95-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXA6-1", "uniprot_id": [ { "id": "A0A098KXA6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXA6", "type": "external" } ], "mass": 40712.0, "length": 366, "protein_name": "Prostaglandin F2-alpha receptor", "gene_name": "Ptgfr", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ptgfr; H671_1g1600", "gene_names_refseq": "", "protein_names_uniprotkb": "Prostaglandin F2-alpha receptor; Prostanoid FP receptor", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100757080)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004958 prostaglandin F receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXA6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXA7-1", "uniprot_id": [ { "id": "A0A098KXA7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXA7", "type": "external" } ], "mass": 42417.0, "length": 404, "protein_name": "Advanced glycosylation end product-specific receptor", "gene_name": "Ager", "organism": "Hamster", "refseq_name": "advanced glycosylation end product-specific receptor isoform X1", "refseq_ac": [ { "id": "XP_003508510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508510", "type": "external" } ], "gene_names_uniprotkb": "Ager; H671_1g3846", "gene_names_refseq": "Ager", "protein_names_uniprotkb": "Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products", "protein_names_refseq": "advanced glycosylation end product-specific receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757624)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003508510.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0044548 S100 protein binding;GO:0005055 laminin receptor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005634 nucleus;GO:0005769 early endosome;GO:0009986 cell surface;GO:0042995 cell projection", "go_biological_process": "GO:1900744 regulation of p38MAPK cascade;GO:0006281 DNA repair;GO:0006954 inflammatory response;GO:0007166 cell surface receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXB5-1", "uniprot_id": [ { "id": "A0A098KXB5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXB5", "type": "external" } ], "mass": 37907.0, "length": 337, "protein_name": "DnaJ heat shock protein family (Hsp40) member B4; DnaJ homolog subfamily B member 4 isoform X1; Putative dnaJ subfamily B member 4", "gene_name": "Dnajb4", "organism": "Hamster", "refseq_name": "dnaJ homolog subfamily B member 4 isoform X1", "refseq_ac": [ { "id": "XP_003496481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496481", "type": "external" } ], "gene_names_uniprotkb": "Dnajb4; H671_1g1604", "gene_names_refseq": "Dnajb4", "protein_names_uniprotkb": "DnaJ heat shock protein family (Hsp40) member B4; DnaJ homolog subfamily B member 4 isoform X1; Putative dnaJ subfamily B member 4", "protein_names_refseq": "dnaJ homolog subfamily B member 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757372)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613622.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030018 Z disc", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXC5-1", "uniprot_id": [ { "id": "A0A098KXC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXC5", "type": "external" } ], "mass": 60944.0, "length": 551, "protein_name": "Solute carrier family 22 (organic anion transporter), member 19; Solute carrier family 22 member 19 isoform X3; Solute carrier family 22 member 9-like protein", "gene_name": "LOC100773204", "organism": "Hamster", "refseq_name": "solute carrier family 22 member 19 isoform X3", "refseq_ac": [ { "id": "XP_027264184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264184", "type": "external" } ], "gene_names_uniprotkb": "LOC100773204; H671_3g10893", "gene_names_refseq": "LOC100773204", "protein_names_uniprotkb": "Solute carrier family 22 (organic anion transporter), member 19; Solute carrier family 22 member 19 isoform X3; Solute carrier family 22 member 9-like protein", "protein_names_refseq": "solute carrier family 22 member 19 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773204)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019534 toxin transmembrane transporter activity;GO:0008514 organic anion transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0015711 organic anion transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXC9-1", "uniprot_id": [ { "id": "A0A098KXC9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXC9", "type": "external" } ], "mass": 42835.0, "length": 376, "protein_name": "26S proteasome non-ATPase regulatory subunit 13", "gene_name": "Psmd13", "organism": "Hamster", "refseq_name": "26S proteasome non-ATPase regulatory subunit 13 isoform X2", "refseq_ac": [ { "id": "XP_003515430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515430", "type": "external" } ], "gene_names_uniprotkb": "Psmd13; H671_3g10427", "gene_names_refseq": "Psmd13", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 13; 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 13 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772429)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1268 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617917.1) and transcript sequence (JP041856.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003515430.2. COMPLETENESS: full length., [RefSeq]; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0007127 meiosis I", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXD8-1", "uniprot_id": [ { "id": "A0A098KXD8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXD8", "type": "external" } ], "mass": 34368.0, "length": 302, "protein_name": "Lysosomal thioesterase PPT2", "gene_name": "Ppt2", "organism": "Hamster", "refseq_name": "lysosomal thioesterase PPT2", "refseq_ac": [ { "id": "XP_003508513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508513", "type": "external" } ], "gene_names_uniprotkb": "Ppt2; H671_1g3843", "gene_names_refseq": "Ppt2", "protein_names_uniprotkb": "Lysosomal thioesterase PPT2; 3.1.2.2", "protein_names_refseq": "lysosomal thioesterase PPT2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758494)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the cleavage of thioester bonds from S-palmitoyl-CoA or S-palmitoyl-N-acetylcysteamine (unbranched structures) but does not have activity against palmitoylcysteine or palmitoylated proteins, branched structures or bulky head groups. Conversely, hydrolyzes both long and short chain fatty acyl-CoA substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" } ], "go_molecular_function": "GO:0047617 fatty acyl-CoA hydrolase activity;GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXD8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXD9-1", "uniprot_id": [ { "id": "A0A098KXD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXD9", "type": "external" } ], "mass": 55495.0, "length": 502, "protein_name": "Cystine/glutamate transporter", "gene_name": "Slc7a11", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc7a11; H671_1g3489", "gene_names_refseq": "", "protein_names_uniprotkb": "Cystine/glutamate transporter; Amino acid transport system xc-; Solute carrier family 7 member 11; xCT", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100764546)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015327 cystine:glutamate antiporter activity;GO:0140926 L-kynurenine transmembrane transporter activity;GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0009986 cell surface;GO:0097449 astrocyte projection;GO:0031526 brush border membrane;GO:0031528 microvillus membrane", "go_biological_process": "GO:1904717 regulation of AMPA glutamate receptor clustering;GO:0051223 regulation of protein transport;GO:0008542 visual learning;GO:0030534 adult behavior;GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXE1-1", "uniprot_id": [ { "id": "A0A098KXE1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXE1", "type": "external" } ], "mass": 56296.0, "length": 519, "protein_name": "Cytosol aminopeptidase", "gene_name": "Lap3", "organism": "Hamster", "refseq_name": "cytosol aminopeptidase", "refseq_ac": [ { "id": "XP_003506025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506025", "type": "external" } ], "gene_names_uniprotkb": "Lap3; H671_1g2904", "gene_names_refseq": "Lap3", "protein_names_uniprotkb": "Cytosol aminopeptidase; 3.4.11.1; 3.4.11.5; 3.4.13.23; Cysteinylglycine-S-conjugate dipeptidase; Leucine aminopeptidase 3; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase", "protein_names_refseq": "cytosol aminopeptidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100768932)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614204.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.1", "type": "external" }, { "id": "3.4.11.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.5", "type": "external" }, { "id": "3.4.13.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.23", "type": "external" }, { "id": "3.4.13.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.18", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXF5-1", "uniprot_id": [ { "id": "A0A098KXF5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXF5", "type": "external" } ], "mass": 91134.0, "length": 805, "protein_name": "Zinc finger protein 711", "gene_name": "Znf711", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Znf711; H671_xg20456", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 711", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100773561)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activated expression of genes involved in neuron development, such as KDM5C. May compete with transcription factor ARX for activation of expression of KDM5C., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXF9-1", "uniprot_id": [ { "id": "A0A098KXF9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXF9", "type": "external" } ], "mass": 59769.0, "length": 530, "protein_name": "Synembryn", "gene_name": "Ric8a", "organism": "Hamster", "refseq_name": "synembryn-A isoform X1", "refseq_ac": [ { "id": "XP_003515555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515555", "type": "external" } ], "gene_names_uniprotkb": "Ric8a; H671_3g10425", "gene_names_refseq": "Ric8a", "protein_names_uniprotkb": "Synembryn; Protein Ric-8", "protein_names_refseq": "synembryn-A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769942)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003618267.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chaperone that specifically binds and folds nascent G alpha proteins prior to G protein heterotrimer formation. Also acts as a guanine nucleotide exchange factor (GEF) for G alpha proteins by stimulating exchange of bound GDP for free GTP., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001965 G-protein alpha-subunit binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0008542 visual learning;GO:0042074 cell migration involved in gastrulation;GO:0001944 vasculature development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000010000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXG8-1", "uniprot_id": [ { "id": "A0A098KXG8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXG8", "type": "external" } ], "mass": 182075.0, "length": 1612, "protein_name": "DNA topoisomerase 2", "gene_name": "Top2b", "organism": "Hamster", "refseq_name": "DNA topoisomerase 2-beta isoform X2", "refseq_ac": [ { "id": "XP_027245183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245183", "type": "external" } ], "gene_names_uniprotkb": "Top2b; H671_1g2063", "gene_names_refseq": "Top2b", "protein_names_uniprotkb": "DNA topoisomerase 2; 5.6.2.2", "protein_names_refseq": "DNA topoisomerase 2-beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770041)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23929341;29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000792 heterochromatin", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0007409 axonogenesis;GO:0030900 forebrain development;GO:0001764 neuron migration;GO:0030183 B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A098KXG8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000010000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MP93-1", "uniprot_id": [ { "id": "A0A0A0MP93_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A0A0MP93", "type": "external" } ], "mass": 14096.0, "length": 130, "protein_name": "Histone H2A", "gene_name": "LOC614881", "organism": "Bovine", "refseq_name": "histone H2A type 3", "refseq_ac": [ { "id": "XP_002694650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694650", "type": "external" } ], "gene_names_uniprotkb": "LOC614881", "gene_names_refseq": "LOC614881", "protein_names_uniprotkb": "Histone H2A", "protein_names_refseq": "histone H2A type 3", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3214815); (R-BTA-3214847); (R-BTA-3214858); (R-BTA-5689603); (R-BTA-5689880); (R-BTA-5689901)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A0MP93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MP99-1", "uniprot_id": [ { "id": "A0A0A0MP99_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A0A0MP99", "type": "external" } ], "mass": 28732.0, "length": 261, "protein_name": "Carbonic anhydrase", "gene_name": "LOC100847874", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100847874", "gene_names_refseq": "", "protein_names_uniprotkb": "Carbonic anhydrase; 4.2.1.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reversible hydration of carbon dioxide. Can hydrate cyanamide to urea., [UniProtKB, UniProtKB, UniProtKB]; Reversible hydration of carbon dioxide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1", "type": "external" }, { "id": "4.2.1.69", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.69", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity;GO:0018820 cyanamide hydratase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A0MP99-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPA4-1", "uniprot_id": [ { "id": "A0A0A0MPA4_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A0A0MPA4", "type": "external" } ], "mass": 13481.0, "length": 123, "protein_name": "40S ribosomal protein S25", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "40S ribosomal protein S25", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A0MPA4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPA5-1", "uniprot_id": [ { "id": "A0A0A0MPA5_BOVIN", "url": "https://www.uniprot.org/uniprot/A0A0A0MPA5", "type": "external" } ], "mass": 11395.0, "length": 100, "protein_name": "Ribosomal biogenesis factor", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribosomal biogenesis factor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0042254 ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A0MPA5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0100000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPH1-1", "uniprot_id": [ { "id": "A0A0A0MPH1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A0MPH1", "type": "external" } ], "mass": 50056.0, "length": 459, "protein_name": "HtrA serine peptidase 4; Serine protease HTRA1", "gene_name": "htra4", "organism": "Zebrafish", "refseq_name": "serine protease HTRA1", "refseq_ac": [ { "id": "XP_017211746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211746", "type": "external" } ], "gene_names_uniprotkb": "htra4", "gene_names_refseq": "htra4", "protein_names_uniprotkb": "HtrA serine peptidase 4; Serine protease HTRA1", "protein_names_refseq": "serine protease HTRA1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334257)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017211746.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z723", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0043065 positive regulation of apoptotic process;GO:0012501 programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0A0MPH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPH9-1", "uniprot_id": [ { "id": "A0A0A0MPH9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A0MPH9", "type": "external" } ], "mass": 21978.0, "length": 199, "protein_name": "Si:ch211-57i17.5; Usherin", "gene_name": "si:ch211-57i17.5", "organism": "Zebrafish", "refseq_name": "usherin", "refseq_ac": [ { "id": "XP_693491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693491", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-57i17.5", "gene_names_refseq": "si:ch211-57i17.5", "protein_names_uniprotkb": "Si:ch211-57i17.5; Usherin", "protein_names_refseq": "usherin", "tax_id": 7955, "disease": "", "pathway": " (dre:565103)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_693491.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TF24", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0A0MPH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPI6-1", "uniprot_id": [ { "id": "A0A0A0MPI6_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A0MPI6", "type": "external" } ], "mass": 22020.0, "length": 211, "protein_name": "Si:dkey-5n18.1; Uncharacterized protein LOC570444 precursor", "gene_name": "c1ql1", "organism": "Zebrafish", "refseq_name": "complement C1q like 1 precursor", "refseq_ac": [ { "id": "NP_001373194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373194", "type": "external" } ], "gene_names_uniprotkb": "c1ql1; si:dkey-5n18.1", "gene_names_refseq": "c1ql1; si:dkey-5n18.1", "protein_names_uniprotkb": "Si:dkey-5n18.1; Uncharacterized protein LOC570444 precursor", "protein_names_refseq": "C1ql3; complement C1q like 1 precursor; complement component 1, q subcomponent-like 1", "tax_id": 7955, "disease": "", "pathway": " (dre:570444)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "18222405;19275900;20615881;23594743;26469318;30304682;35072520", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01037591.1, EH472747.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505381, SAMEA4476746 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Aug 15, 2020 this sequence version replaced XP_699016.3., [RefSeq]; Conserved recoding RNA editing of vertebrate C1q-related factor C1QL1., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T6Y0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005581 collagen trimer", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0A0MPI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPL5-1", "uniprot_id": [ { "id": "A0A0A0MPL5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A0MPL5", "type": "external" } ], "mass": 54598.0, "length": 494, "protein_name": "Fascin", "gene_name": "fscn1b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "fscn1b", "gene_names_refseq": "", "protein_names_uniprotkb": "Fascin", "protein_names_refseq": "", "tax_id": 7955, "disease": "pancreatic cancer (Disease Ontology:DOID:1793); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); common bile duct neoplasm (Disease Ontology:DOID:4608); cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (dre:570314)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PPJ3", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0030175 filopodium", "go_biological_process": "GO:0016477 cell migration;GO:0051017 actin filament bundle assembly;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0A0MPL5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MPW9-1", "uniprot_id": [ { "id": "A0A0A0MPW9_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A0MPW9", "type": "external" } ], "mass": 64528.0, "length": 571, "protein_name": "Heat shock 70 kDa protein 12A; Heat shock protein family A (Hsp70) member 12A.2", "gene_name": "hspa12a.2", "organism": "Zebrafish", "refseq_name": "heat shock 70 kDa protein 12A", "refseq_ac": [ { "id": "XP_003198604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198604", "type": "external" } ], "gene_names_uniprotkb": "hspa12a.2; si:dkey-61p9.4", "gene_names_refseq": "hspa12a.2", "protein_names_uniprotkb": "Heat shock 70 kDa protein 12A; Heat shock protein family A (Hsp70) member 12A.2", "protein_names_refseq": "heat shock 70 kDa protein 12A", "tax_id": 7955, "disease": "", "pathway": " (dre:559237)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1REZ1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0A0MPW9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MQ47-1", "uniprot_id": [ { "id": "A0A0A0MQ47_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0A0MQ47", "type": "external" } ], "mass": 49937.0, "length": 436, "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "organism": "Chicken", "refseq_name": "N-lysine methyltransferase SMYD2", "refseq_ac": [ { "id": "NP_001264500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264500", "type": "external" } ], "gene_names_uniprotkb": "SMYD2", "gene_names_refseq": "SMYD2", "protein_names_uniprotkb": "N-lysine methyltransferase SMYD2; 2.1.1.354; Histone methyltransferase SMYD2; SET and MYND domain-containing protein 2", "protein_names_refseq": "N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; histone methyltransferase SMYD2", "tax_id": 9031, "disease": "", "pathway": " (gga:421361)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22241783", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BX950800.1, HAEK01013253.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Apr 12, 2013 this sequence version replaced XP_419420.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]; Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'., [UniProtKB, UniProtKB, UniProtKB]; The cytoplasmic protein chaperone Hsp90 is methylated by the lysine methyltransferase Smyd2 in various cell types, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000993 RNA polymerase II complex binding;GO:0002039 p53 binding;GO:0046975 histone H3K36 methyltransferase activity;GO:0140999 histone H3K4 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0A0MQ47-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MQ60-1", "uniprot_id": [ { "id": "A0A0A0MQ60_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0A0MQ60", "type": "external" } ], "mass": 40608.0, "length": 361, "protein_name": "Melatonin receptor 1B", "gene_name": "MTNR1B", "organism": "Chicken", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MTNR1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Melatonin receptor 1B", "protein_names_refseq": "", "tax_id": 9031, "disease": "", "pathway": " (gga:396338); (R-GGA-373076); (R-GGA-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008502 melatonin receptor activity;GO:1904408 melatonin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0042593 glucose homeostasis;GO:0050796 regulation of insulin secretion;GO:0045820 negative regulation of glycolytic process;GO:0046325 negative regulation of D-glucose import", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A0MQ60-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MQA4-1", "uniprot_id": [ { "id": "A0A0A0MQA4_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0A0MQA4", "type": "external" } ], "mass": 12148.0, "length": 119, "protein_name": "Keratin associated protein 12-22", "gene_name": "Krtap12-22", "organism": "Mouse", "refseq_name": "uncharacterized protein LOC100009614", "refseq_ac": [ { "id": "NP_001074921", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074921", "type": "external" } ], "gene_names_uniprotkb": "Krtap12-22; 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Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 4, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0A0MS00-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MS01-1", "uniprot_id": [ { "id": "TVG10_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0A0MS01", "type": "external" } ], "mass": 13482.0, "length": 119, "protein_name": "Probable non-functional T cell receptor gamma variable 10", "gene_name": "TRGV10", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGV10", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor gamma variable 10", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "23348415;24387714;24600447;25674089;28920588;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) gamma chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0A0MS01-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MS02-1", "uniprot_id": [ { "id": "TRGV1_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0A0MS02", "type": "external" } ], "mass": 13248.0, "length": 117, "protein_name": "Probable non-functional T cell receptor gamma variable", "gene_name": "TRGV1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGV1", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor gamma variable", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "23348415;24387714;24600447;25674089;28920588;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) gamma chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0A0MS02-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MS03-1", "uniprot_id": [ { "id": "TVB53_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0A0MS03", "type": "external" } ], "mass": 12596.0, "length": 114, "protein_name": "Probable non-functional T cell receptor beta variable 5-3", "gene_name": "TRBV5-3", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV5-3", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor beta variable 5-3", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 3, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0A0MS03-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MS04-1", "uniprot_id": [ { "id": "TVB67_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0A0MS04", "type": "external" } ], "mass": 12588.0, "length": 114, "protein_name": "Probable non-functional T cell receptor beta variable 6-7", "gene_name": "TRBV6-7", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV6-7", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor beta variable 6-7", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;34509645;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 6, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0A0MS04-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MS05-1", "uniprot_id": [ { "id": "TVB57_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0A0MS05", "type": "external" } ], "mass": 12386.0, "length": 114, "protein_name": "Probable non-functional T cell receptor beta variable 5-7", "gene_name": "TRBV5-7", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV5-7", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor beta variable 5-7", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 7, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0A0MS05-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A0MS06-1", "uniprot_id": [ { "id": "TVB23_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0A0MS06", "type": "external" } ], "mass": 12785.0, "length": 115, "protein_name": "Probable non-functional T cell receptor beta variable 23-1", "gene_name": "TRBV23-1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV23-1", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable non-functional T cell receptor beta variable 23-1", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;9619395", "class_list": "", "function": "Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447). Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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61708.0, "length": 544, "protein_name": "POTE ankyrin domain family member B", "gene_name": "POTEB2; POTEB3; POTEB", "organism": "Human", "refseq_name": "POTE ankyrin domain family member B2", "refseq_ac": [ { "id": "NP_001264232", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264232", "type": "external" } ], "gene_names_uniprotkb": "POTEB2; POTEB3; POTEB; LOC102723502; POTEB2; POTEB", "gene_names_refseq": "POTE-15; POTEB2; POTEB", "protein_names_uniprotkb": "POTE ankyrin domain family member B; ANKRD26-like family B member 1; POTE-15; Prostate, ovary, testis-expressed protein on chromosome 15", "protein_names_refseq": "ANKRD26-like family B member 1; POTE ankyrin domain family member B2; POTE ankyrin domain family member B; Prostate, ovary, testis-expressed protein on chromosome 15", "tax_id": 9606, "disease": "", "pathway": " (hsa:100287399); (hsa:100996331)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11237011;15276201;32387766;32938616;35051231;38740147", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q495V7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0A6YYL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A6YYP6-1", "uniprot_id": [ { "id": "A0A0A6YYP6_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0A6YYP6", "type": "external" } ], "mass": 44037.0, "length": 397, "protein_name": "Tyrosine-protein phosphatase non-receptor type substrate 1", "gene_name": "Sirpb1a", "organism": "Mouse", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Sirpb1a; SIRP-beta", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type substrate 1; Brain Ig-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-1", "protein_names_refseq": "", "tax_id": 10090, "disease": "", "pathway": " (mmu:320832)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10.1101/2023.09.13.557529;15123631;21750661", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 2, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 9562, "biomarker_type": "", "glycan_count": 2, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006909 phagocytosis;GO:0032675 regulation of interleukin-6 production;GO:0050766 positive regulation of phagocytosis;GO:0050765 negative regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0A6YYP6-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000000100000.1000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A7BZR3-1", "uniprot_id": [ { "id": "A0A0A7BZR3_PIG", "url": "https://www.uniprot.org/uniprot/A0A0A7BZR3", "type": "external" } ], "mass": 40034.0, "length": 361, "protein_name": "MHC class I antigen", "gene_name": "SLA-1", "organism": "Pig", "refseq_name": "MHC class I antigen 1 isoform X2", "refseq_ac": [ { "id": "XP_013833010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833010", "type": "external" } ], "gene_names_uniprotkb": "SLA-1", "gene_names_refseq": "SLA-1", "protein_names_uniprotkb": "MHC class I antigen", "protein_names_refseq": "MHC class I antigen 1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037293)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AFM5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030670 phagocytic vesicle membrane;GO:0042612 MHC class I protein complex;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0006955 immune response;GO:0002474 antigen processing and presentation of peptide antigen via MHC class I", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A7BZR3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A7EPL0-1", "uniprot_id": [ { "id": "PIAL1_ARATH", "url": "https://www.uniprot.org/uniprot/A0A0A7EPL0", "type": "external" } ], "mass": 93475.0, "length": 847, "protein_name": "E4 SUMO-protein ligase PIAL1", "gene_name": "PIAL1", "organism": "Arabidopsis", "refseq_name": "zinc ion binding protein", "refseq_ac": [ { "id": "NP_172366", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_172366", "type": "external" } ], "gene_names_uniprotkb": "PIAL1; EMB3001; F7G19.21", "gene_names_refseq": "F7G19.21; F7G19_21; PIAL1; PROTEIN INHIBITOR OF ACTIVATED STAT LIKE 1; embryo defective 3001", "protein_names_uniprotkb": "E4 SUMO-protein ligase PIAL1; 2.3.2.-; Protein EMBRYO DEFECTIVE 3001; Protein INHIBITOR OF ACTIVATED STAT-LIKE 1", "protein_names_refseq": "zinc ion binding protein", "tax_id": 3702, "disease": "", "pathway": " (ath:AT1G08910)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11130712;25415977;27113777;27862469", "class_list": "", "function": "Together with MOM1 and PIAL2, regulates transcriptional gene silencing (TGS) independently of changes in DNA methylation (PubMed:27113777). E4-type SUMO ligase that promotes SUMO chain formation in a SCE1-dependent manner and thus contributes to a pathway for proteolytic removal of sumoylation substrates (PubMed:25415977). Involved in stress responses (e.g. osmotic, salt and abscisic acid ABA) and sulfur metabolism (PubMed:25415977)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F4HXS5;O04038", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019789 SUMO transferase activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006970 response to osmotic stress;GO:0016925 protein sumoylation;GO:0009651 response to salt stress;GO:0060966 regulation of gene silencing by regulatory ncRNA;GO:0009737 response to abscisic acid", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0A7EPL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.1000000000000000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A7H8E2-1", "uniprot_id": [ { "id": "A0A0A7H8E2_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A7H8E2", "type": "external" } ], "mass": 20383.0, "length": 175, "protein_name": "Neurotensin/neuromedin N", "gene_name": "nts", "organism": "Zebrafish", "refseq_name": "neurotensin/neuromedin N", "refseq_ac": [ { "id": "XP_017207567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207567", "type": "external" } ], "gene_names_uniprotkb": "nts", "gene_names_refseq": "nts", "protein_names_uniprotkb": "Neurotensin/neuromedin N", "protein_names_refseq": "neurotensin/neuromedin N", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); sciatic neuropathy (Disease Ontology:DOID:11446); depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dre:101884890); (R-DRE-375276); (R-DRE-416476)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0030133 transport vesicle", "go_biological_process": "GO:0097746 blood vessel diameter maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0A7H8E2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A8JWS4-1", "uniprot_id": [ { "id": "A0A0A8JWS4_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A8JWS4", "type": "external" } ], "mass": 42116.0, "length": 380, "protein_name": "Leukotriene B4 receptor 1", "gene_name": "ltb4r", "organism": "Zebrafish", "refseq_name": "leukotriene B4 receptor 1", "refseq_ac": [ { "id": "NP_001295904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295904", "type": "external" } ], "gene_names_uniprotkb": "ltb4r; LTB4R; si:ch211-272h9.1; si:ch211-272h9.2", "gene_names_refseq": "ltb4r; si:ch211-272h9.1; si:ch211-272h9.2", "protein_names_uniprotkb": "Leukotriene B4 receptor 1", "protein_names_refseq": "BLT1; leukotriene B4 receptor 1", "tax_id": 7955, "disease": "carotid artery disease (Disease Ontology:DOID:3407)", "pathway": " (dre:100329657); (R-DRE-391906); (R-DRE-416476)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "15520368;23594743;25738285;26469318;27189481;29348261;31526847;31673028;33436952;34292151", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: LC009449.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505384, SAMEA4476733 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from LC009449.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008528 G protein-coupled peptide receptor activity;GO:0001632 leukotriene B4 receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0055113 epiboly involved in gastrulation with mouth forming second", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0A8JWS4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A8P3N1-1", "uniprot_id": [ { "id": "A0A0A8P3N1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0A8P3N1", "type": "external" } ], "mass": 18965.0, "length": 166, "protein_name": "Lymphocyte antigen 86", "gene_name": "ly86", "organism": "Zebrafish", "refseq_name": "lymphocyte antigen 86 precursor", "refseq_ac": [ { "id": "NP_001297417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297417", "type": "external" } ], "gene_names_uniprotkb": "ly86; ly86_tv1; ly86_tv2", "gene_names_refseq": "ly86_tv1; ly86_tv2; ly86", "protein_names_uniprotkb": "Lymphocyte antigen 86", "protein_names_refseq": "Md1; lymphocyte antigen 86 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:101886351)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;25681741;27402697", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: LN624113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from LN624113.1., [RefSeq]; Genetic inhibition of zebrafish Md1 and Rp105 reveals that Md1 or Rp105 deficiency impairs the expression of genes encoding pro-inflammatory and antiviral molecules, leading to increased susceptibility to viral infection., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7W3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007399 nervous system development;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0009615 response to virus;GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0A8P3N1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0A8WJ47-1", "uniprot_id": [ { "id": "A0A0A8WJ47_CHICK", "url": "https://www.uniprot.org/uniprot/A0A0A8WJ47", "type": "external" } ], "mass": 7109.0, "length": 62, "protein_name": "OvoDB1; Ovodefensin B1", "gene_name": "OvoDB1", "organism": "Chicken", "refseq_name": "ovodefensin B1 precursor", "refseq_ac": [ { "id": "NP_001304068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304068", "type": "external" } ], "gene_names_uniprotkb": "OvoDB1; OVODB1", "gene_names_refseq": "OVODB1", "protein_names_uniprotkb": "OvoDB1; Ovodefensin B1", "protein_names_refseq": "ovodefensin B1 precursor", "tax_id": 9031, "disease": "", "pathway": " (gga:106780806)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: LN717248.1, SRR12888552.205447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMN06140852 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000070.1 and LN717248.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0A8WJ47-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0001000000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1A5-1", "uniprot_id": [ { "id": "A0A0B4J1A5_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1A5", "type": "external" } ], "mass": 64933.0, "length": 626, "protein_name": "EWS RNA-binding protein 1a", "gene_name": "ewsr1a", "organism": "Zebrafish", "refseq_name": "EWS RNA-binding protein 1a", "refseq_ac": [ { "id": "NP_001108610", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108610", "type": "external" } ], "gene_names_uniprotkb": "ewsr1a; EWSR1; fc04c01; wu:fc04c01", "gene_names_refseq": "EWSR1; ewsr1a; fc04c01; wu:fc04c01", "protein_names_uniprotkb": "EWS RNA-binding protein 1a", "protein_names_refseq": "EWS RNA-binding protein 1a; Ewing sarcoma breakpoint region 1a; Ewing sarcoma breakpoint region 1", "tax_id": 7955, "disease": "Ewing sarcoma (Disease Ontology:DOID:3369)", "pathway": " (dre:323597)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "17912356;19417137;23594743;25617839;26100283;27189481;27557633;27898262;30165106;30631305", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC056281.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN835703.1, BC068397.1, FP154885.1, DT075886.1, FP131351.1 and EH467947.1. On Mar 7, 2008 this sequence version replaced XP_685548.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Ewsr1 maintains mitotic integrity and proneural cell survival in early zebrafish development Publication Status: Online-Only, [RefSeq, PubMed]; Interaction between EWSR1/FLI1 and EWSR1 in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation., [RefSeq, PubMed]; Mutation of the EWS gene modulates Sox9 gene expression essential for chondrocyte differentiation. Erratum:[PLoS One. 2015 Mar 30;10(3):e0123487. doi: 10.1371/journal.pone.0123487. PMID: 25822618] Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1TRE3", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0006355 regulation of DNA-templated transcription;GO:0007088 regulation of mitotic nuclear division;GO:0021954 central nervous system neuron development;GO:0051256 mitotic spindle midzone assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0B4J1A5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1A8-1", "uniprot_id": [ { "id": "A0A0B4J1A8_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1A8", "type": "external" } ], "mass": 72112.0, "length": 642, "protein_name": "3.1.3.48; Ubiquitin-associated and SH3 domain-containing Bb", "gene_name": "ubash3bb", "organism": "Zebrafish", "refseq_name": "ubiquitin associated and SH3 domain containing Bb", "refseq_ac": [ { "id": "NP_001122227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122227", "type": "external" } ], "gene_names_uniprotkb": "ubash3bb; zgc:195004", "gene_names_refseq": "ubash3bb; zgc:195004", "protein_names_uniprotkb": "3.1.3.48; Ubiquitin-associated and SH3 domain-containing Bb", "protein_names_refseq": "ubiquitin associated and SH3 domain containing Bb", "tax_id": 7955, "disease": "", "pathway": " (dre:569827)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC163484.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505390, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC163484.1. On Jul 31, 2008 this sequence version replaced XP_698329.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NKP3", "ec_number_list": [], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0B4J1A8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1B0-1", "uniprot_id": [ { "id": "A0A0B4J1B0_DANRE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1B0", "type": "external" } ], "mass": 66582.0, "length": 607, "protein_name": "Insulin-like growth factor 2 mRNA-binding protein 2a", "gene_name": "igf2bp2a", "organism": "Zebrafish", "refseq_name": "insulin-like growth factor 2 mRNA-binding protein 2a", "refseq_ac": [ { "id": "NP_001108030", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108030", "type": "external" } ], "gene_names_uniprotkb": "igf2bp2a; crfb14; crfb16; igf2bp2; si:ch211-125m20.1", "gene_names_refseq": "crfb14; crfb16; igf2bp2a; igf2bp2; si:ch211-125m20.1", "protein_names_uniprotkb": "Insulin-like growth factor 2 mRNA-binding protein 2a", "protein_names_refseq": "IGF-II mRNA-binding protein 2a; cytokine receptor family member b16; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2a", "tax_id": 7955, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:100136839)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "18803835;21048110;23451191;23594743;26325373;26469318;26963759;34352271", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DQ998838.1, EU296401.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ998838.1. On Aug 9, 2008 this sequence version replaced NP_001108030.1., [RefSeq]; IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NFP1", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0070934 CRD-mediated mRNA stabilization;GO:0006417 regulation of translation;GO:0007399 nervous system development;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4J1B0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000000001.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1F3-1", "uniprot_id": [ { "id": "A0A0B4J1F3_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1F3", "type": "external" } ], "mass": 73574.0, "length": 663, "protein_name": "Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6", "gene_name": "Lilra6", "organism": "Mouse", "refseq_name": "paired-Ig-like receptor A3 precursor", "refseq_ac": [ { "id": "NP_035220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035220", "type": "external" } ], "gene_names_uniprotkb": "Lilra6", "gene_names_refseq": "7M1; Lilra6; Pira3", "protein_names_uniprotkb": "Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6", "protein_names_refseq": "paired-Ig-like receptor A3 precursor; paired-Ig-like receptor A3", "tax_id": 10090, "disease": "", "pathway": " (mmu:18726)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 7, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032396 inhibitory MHC class I receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0019221 cytokine-mediated signaling pathway;GO:0002764 immune response-regulating signaling pathway;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0B4J1F3-1", "record_type": "protein", "filter_code": "0000000.1000101.100000.0000000000100000.0000000001000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1F4-1", "uniprot_id": [ { "id": "ARRD4_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1F4", "type": "external" } ], "mass": 44970.0, "length": 415, "protein_name": "Arrestin domain-containing protein 4", "gene_name": "Arrdc4", "organism": "Mouse", "refseq_name": "arrestin domain-containing protein 4 isoform 1", "refseq_ac": [ { "id": "NP_001036057", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036057", "type": "external" } ], "gene_names_uniprotkb": "Arrdc4", "gene_names_refseq": "2410003C09Rik; Arrdc4", "protein_names_uniprotkb": "Arrestin domain-containing protein 4", "protein_names_refseq": "arrestin domain-containing protein 4 isoform 1; arrestin domain-containing protein 4", "tax_id": 10090, "disease": "", "pathway": " (mmu:66412)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "19605364;27462458;32152506;35950500;37451484;38528189;38946541", "class_list": "", "function": "An insulin-regulated arrestin domain protein controls hepatic glucagon action., [RefSeq, PubMed]; Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:27462458). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (By similarity). Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). May play a role in glucose uptake (By similarity). Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65 (By similarity)., [UniProtKB, PubMed, UniProtKB]; Identification of HDAC9 and ARRDC4 as potential biomarkers and targets for treatment of type 2 diabetes. Publication Status: Online-Only, [RefSeq, PubMed]; Interaction of ARRDC4 With GLUT1 Mediates Metabolic Stress in the Ischemic Heart., [RefSeq, PubMed]; Systemic Deletion of ARRDC4 Improves Cardiac Reserve and Exercise Capacity in Diabetes., [RefSeq, PubMed]; Txnip regulates cellular metabolism independent of its binding to thioredoxin and the arrestin domains are crucial structural elements in metabolic functions of alpha-arrestin proteins, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8VD69", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005768 endosome;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0016567 protein ubiquitination;GO:0070534 protein K63-linked ubiquitination;GO:0032728 positive regulation of interferon-beta production;GO:0140112 extracellular vesicle biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0B4J1F4-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1F6-1", "uniprot_id": [ { "id": "A0A0B4J1F6_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1F6", "type": "external" } ], "mass": 20895.0, "length": 192, "protein_name": "T cell immunoglobulin and mucin domain containing 6", "gene_name": "Timd6", "organism": "Mouse", "refseq_name": "uncharacterized protein LOC407814 precursor", "refseq_ac": [ { "id": "NP_001020606", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020606", "type": "external" } ], "gene_names_uniprotkb": "Timd6", "gene_names_refseq": "Timd6", "protein_names_uniprotkb": "T cell immunoglobulin and mucin domain containing 6", "protein_names_refseq": "hepatitis A virus cellular receptor 1-like family member; uncharacterized protein LOC407814 precursor", "tax_id": 10090, "disease": "essential hypertension (Disease Ontology:DOID:10825); hydronephrosis (Disease Ontology:DOID:11111); acute kidney tubular necrosis (Disease Ontology:DOID:12556); renovascular hypertension (Disease Ontology:DOID:1591); hyperuricemia (Disease Ontology:DOID:1920); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); asthma (Disease Ontology:DOID:2841); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); atopic dermatitis (Disease Ontology:DOID:3310); renal cell carcinoma (Disease Ontology:DOID:4450); kidney disease (Disease Ontology:DOID:557); hepatocellular carcinoma (Disease Ontology:DOID:684); vesicoureteral reflux (Disease Ontology:DOID:9620)", "pathway": " (mmu:407814)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21750661", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001618 virus receptor activity;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0033005 positive regulation of mast cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0B4J1F6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1F8-1", "uniprot_id": [ { "id": "A0A0B4J1F8_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1F8", "type": "external" } ], "mass": 8576.0, "length": 78, "protein_name": "Protein Smim10l2a", "gene_name": "Smim10l2a", "organism": "Mouse", "refseq_name": "non-protein coding RNA 86", "refseq_ac": [ { "id": "NP_898851", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_898851", "type": "external" } ], "gene_names_uniprotkb": "Smim10l2a; 6330419J24Rik", "gene_names_refseq": "6330419J24Rik; Ncrna00086; Smim10l2a", "protein_names_uniprotkb": "Protein Smim10l2a", "protein_names_refseq": "non-protein coding RNA 86", "tax_id": 10090, "disease": "", "pathway": " (mmu:320237)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0B4J1F8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1F9-1", "uniprot_id": [ { "id": "A0A0B4J1F9_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1F9", "type": "external" } ], "mass": 208219.0, "length": 1599, "protein_name": "Trichohyalin", "gene_name": "Tchh", "organism": "Mouse", "refseq_name": "trichohyalin", "refseq_ac": [ { "id": "NP_001156570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156570", "type": "external" } ], "gene_names_uniprotkb": "Tchh", "gene_names_refseq": "AHF; Tchh; Thh", "protein_names_uniprotkb": "Trichohyalin", "protein_names_refseq": "hair follicle protein AHF; trichohyalin", "tax_id": 10090, "disease": "", "pathway": " (mmu:99681); (R-MMU-6809371)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12853460;21750661;25428506", "class_list": "", "function": "Trichohyalin is a multi-functional cross-bridging protein that functions in the inner root sheath and other specialized epithelial tissues, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0046914 transition metal ion binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0001533 cornified envelope", "go_biological_process": "GO:0045109 intermediate filament organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0B4J1F9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.0000000000100000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1G0-1", "uniprot_id": [ { "id": "FCG3A_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1G0", "type": "external" } ], "mass": 28398.0, "length": 249, "protein_name": "Low affinity immunoglobulin gamma Fc region receptor III-A", "gene_name": "Fcgr4", "organism": "Mouse", "refseq_name": "low affinity immunoglobulin gamma Fc region receptor III-A precursor", "refseq_ac": [ { "id": "NP_653142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_653142", "type": "external" } ], "gene_names_uniprotkb": "Fcgr4; Fcgr3a", "gene_names_refseq": "4833442P21Rik; CD16-2; FcgRIV; FcgammaRIV; Fcgr3a; Fcgr4; Fcrl3", "protein_names_uniprotkb": "Low affinity immunoglobulin gamma Fc region receptor III-A; CD16-2; FcgammaRIV; IgG Fc receptor III-A", "protein_names_refseq": "Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc gammaRIV; Fc receptor-like 3; IgG Fc receptor III-A; low affinity immunoglobulin gamma Fc region receptor III-A precursor; low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma Fc region receptor IV", "tax_id": 10090, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); lymphoplasmacytic lymphoma (Disease Ontology:DOID:0060901); lupus nephritis (Disease Ontology:DOID:0080162); graft-versus-host disease (Disease Ontology:DOID:0081267); immunodeficiency 20 (Disease Ontology:DOID:0111941); allergic disease (Disease Ontology:DOID:1205); Behcet's disease (Disease Ontology:DOID:13241); temporal arteritis (Disease Ontology:DOID:13375); polyneuropathy (Disease Ontology:DOID:1389); thrombocytopenia due to platelet alloimmunization (Disease Ontology:DOID:1587); epilepsy (Disease Ontology:DOID:1826); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); IgA glomerulonephritis (Disease Ontology:DOID:2986); coronary artery disease (Disease Ontology:DOID:3393); allergic rhinitis (Disease Ontology:DOID:4481); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); pneumonia (Disease Ontology:DOID:552); lymphopenia (Disease Ontology:DOID:614); myositis (Disease Ontology:DOID:633); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); arthritis (Disease Ontology:DOID:848); Crohn's disease (Disease Ontology:DOID:8778); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (mmu:246256); (R-MMU-163125); (R-MMU-6798695)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10.1101/2023.09.13.557529;12389094;16039578;16709862;17558411;18097064;18292508;18949059;19144319;19795417;24412922;25824719;28389502;28935714;34428180;34485821", "class_list": "", "function": "Fc gammaRIV (Fc fragment of IgG, low affinity IIIa, receptor) is restricted to myeloid lineage cells, and binds to IgG2a and IgG2b with intermediate affinity., [RefSeq, PubMed]; Identification of its gene, [RefSeq, PubMed]; Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG) (PubMed:16039578). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Recognizes neutralizing virus-specific IgGs displayed on the cell surface of infected cells and triggers antibody-dependent cellular cytotoxicity (ADCC). Confers protection to lethal influenza virus infection (PubMed:24412922). On splenic dendritic cells, uptakes antigen immune complexes and efficiently divert them into MHC class I and II antigen presentation pathways to provide for superior priming of CD4-positive and CD8-positive T cell immune responses (PubMed:28389502). Mediates neutrophil activation by IgG complexes redundantly with FCGR2A (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Also acts as a receptor for the Fc region of immunoglobulin epsilon (IgE) (PubMed:17558411, PubMed:18949059). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of pro-inflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). Mediates enhanced ADCC in response to afucosylated IgGs (PubMed:34485821)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; The length of the stalk region of the alpha-chain is an important determinant of Fc gamma receptor IIIA stability on the cell surface., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 9835, "biomarker_type": "", "glycan_count": 1, "disease_count": 27, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q3TC44;Q8R2R4;Q8R477", "ec_number_list": [], "go_molecular_function": "GO:0019767 IgE receptor activity;GO:0019863 IgE binding;GO:0019864 IgG binding;GO:0019770 IgG receptor activity;GO:0140375 immune receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0002468 dendritic cell antigen processing and presentation;GO:0045780 positive regulation of bone resorption;GO:0042119 neutrophil activation;GO:0043320 natural killer cell degranulation;GO:0160006 Fc receptor-mediated immune complex endocytosis", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "A0A0B4J1G0-1", "record_type": "protein", "filter_code": "0000000.1100111.100000.0000000000100000.1000000010001.101.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1G4-1", "uniprot_id": [ { "id": "A0A0B4J1G4_MOUSE", "url": "https://www.uniprot.org/uniprot/A0A0B4J1G4", "type": "external" } ], "mass": 22349.0, "length": 205, "protein_name": "Interleukin 17D", "gene_name": "Il17d", "organism": "Mouse", "refseq_name": "interleukin-17D precursor", "refseq_ac": [ { "id": "NP_665836", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_665836", "type": "external" } ], "gene_names_uniprotkb": "Il17d", "gene_names_refseq": "IL-17D; Il17d", "protein_names_uniprotkb": "Interleukin 17D", "protein_names_refseq": "interleukin-17D precursor", "tax_id": 10090, "disease": "", "pathway": " (mmu:239114)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21750661;27545889;27940089;30209334", "class_list": "", "function": "A new role for nuclear factor erythroid-derived 2-like 2 (Nrf2) in regulating early anti-cancer immune responses by inducing IL-17D and recruiting natural killer (NK) cells. Review article, [RefSeq, PubMed]; Mice deficient in IL-17D or the transcription factor Nuclear factor (erythroid-derived 2)-like 2 (Nrf2), an inducer of IL-17D, featured an early decreased number of innate immune cells at the point of viral entry and were more susceptible to mouse cytomegalovirus infection. Publication Status: Online-Only, [RefSeq, PubMed]; Nrf2 Induces IL-17D to mediate tumor and virus surveillance., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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Publication Status: Online-Only, [RefSeq, PubMed]; GPR15LG regulates psoriasis-like inflammation by down-regulating inflammatory factors on keratinocytes., [RefSeq, PubMed]; Has antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Actinomyces spec., and Mycoplasma hominis and lentivirus., [UniProtKB, UniProtKB]; Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15 (PubMed:28900043, PubMed:28936214). May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (By similarity). May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation (PubMed:35704588)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0B4J1U3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1U4-1", "uniprot_id": [ { "id": "TRGV5_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J1U4", "type": "external" } ], "mass": 13601.0, "length": 118, "protein_name": "T cell receptor gamma variable 5", "gene_name": "TRGV5", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRGV5; TCRGV5", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor gamma variable 5", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "23348415;24387714;24600447;25674089;28920588;38253038", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588). Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089). Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 12, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A0B4J1U4-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0100000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J1U6-1", "uniprot_id": [ { "id": "TVB9_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J1U6", "type": "external" } ], "mass": 12608.0, "length": 114, "protein_name": "T cell receptor beta variable 9", "gene_name": "TRBV9", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRBV9; TCRBV1S1A1N1", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor beta variable 9", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;27568928;8020962;8650574", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 9, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0042101 T cell receptor complex", "go_biological_process": "GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0B4J245-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J248-1", "uniprot_id": [ { "id": "TVA11_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J248", "type": "external" } ], "mass": 11926.0, "length": 108, "protein_name": "T cell receptor alpha variable 1-1", "gene_name": "TRAV1-1", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAV1-1", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha variable 1-1", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 7, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex", "go_biological_process": "GO:0009617 response to bacterium;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0B4J265-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J266-1", "uniprot_id": [ { "id": "TVA41_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J266", "type": "external" } ], "mass": 12352.0, "length": 112, "protein_name": "T cell receptor alpha variable 41", "gene_name": "TRAV41", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAV41", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha variable 41", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "15040585;20452950;23524462;24600447;25493333;33298915", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 6, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex", "go_biological_process": "GO:0009617 response to bacterium;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4J279-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0000000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J280-1", "uniprot_id": [ { "id": "TVA40_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J280", "type": "external" } ], "mass": 11556.0, "length": 105, "protein_name": "T cell receptor alpha variable 40", "gene_name": "TRAV40", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRAV40", "gene_names_refseq": "", "protein_names_uniprotkb": "T cell receptor alpha variable 40", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "15040585;20452950;23524462;24600447;25493333", "class_list": "", "function": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. 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Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462). The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0A0B4J2E0-1", "record_type": "protein", "filter_code": "0000000.1000100.100000.0000000001000000.0100000010000.001.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J2F0-1", "uniprot_id": [ { "id": "PIOS1_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J2F0", "type": "external" } ], "mass": 6313.0, "length": 54, "protein_name": "Protein PIGBOS1", "gene_name": "PIGBOS1", "organism": "Human", "refseq_name": "protein PIGBOS1", "refseq_ac": [ { "id": "NP_001295350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295350", "type": "external" } ], "gene_names_uniprotkb": "PIGBOS1", "gene_names_refseq": "HP06981; PIGBOS1", "protein_names_uniprotkb": "Protein PIGBOS1; PIGB opposite strand protein 1", "protein_names_refseq": "PIGB opposite strand protein 1; protein PIGBOS1", "tax_id": 9606, "disease": "", "pathway": " (hsa:101928527)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11237011;31611695;31653868;32488085;36241641", "class_list": "", "function": "PIGBOS regulates the unfolded protein response (UPR). PIGBOS localizes to the mitochondrial outer membrane where it interacts with the ER protein CLCC1 at ER-mitochondria contact sites. Functional studies reveal that the loss of PIGBOS leads to heightened UPR and increased cell death. Publication Status: Online-Only, [RefSeq, PubMed]; Plays a role in regulation of the unfolded protein response triggered by endoplasmic reticulum (ER) stress resulting from the presence of unfolded proteins in the ER lumen., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006986 response to unfolded protein;GO:1900101 regulation of endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0B4J2F0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J2H0-1", "uniprot_id": [ { "id": "HV69D_HUMAN", "url": "https://www.uniprot.org/uniprot/A0A0B4J2H0", "type": "external" } ], "mass": 12660.0, "length": 117, "protein_name": "Immunoglobulin heavy variable 1-69D", "gene_name": "IGHV1-69D", "organism": "Human", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGHV1-69D", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy variable 1-69D", "protein_names_refseq": "", "tax_id": 9606, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "11340299;17576170;20176268;22158414;24600447", "class_list": "", "function": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0B4J2H0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.0000000001000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J2J0-1", "uniprot_id": [ { "id": "A0A0B4J2J0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0B4J2J0", "type": "external" } ], "mass": 39980.0, "length": 353, "protein_name": "High affinity immunoglobulin gamma Fc receptor I", "gene_name": "Fcgr1a", "organism": "Rat", "refseq_name": "high affinity immunoglobulin gamma Fc receptor I precursor", "refseq_ac": [ { "id": "NP_001094306", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094306", "type": "external" } ], "gene_names_uniprotkb": "Fcgr1a", "gene_names_refseq": "FcgammaRI; Fcgr1a; Fcgr1b; Fcgr1", "protein_names_uniprotkb": "High affinity immunoglobulin gamma Fc receptor I; Fc-gamma RI", "protein_names_refseq": "Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; high affinity IgG Fc receptor, subunit beta; high affinity immunoglobulin gamma Fc receptor I precursor; high-affinity immunoglobulin gamma Fc receptor I", "tax_id": 10116, "disease": "rheumatoid arthritis (Disease Ontology:DOID:7148); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (rno:295279); (R-RNO-1236978); (R-RNO-2029481); (R-RNO-2029482); (R-RNO-2029485)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "23791745;31640731;32510872", "class_list": "", "function": "Expression of TNF-alpha and IL-10 in microglia was elevated to protective levels by neuron-derived IgG at a physiologic level via the FcgammaR I and TLR4 pathways., [RefSeq, PubMed]; Fcgamma Receptor I-Coupled Signaling in Peripheral Nociceptors Mediates Joint Pain in a Rat Model of Rheumatoid Arthritis., [RefSeq, PubMed]; FcgammaRI is a critical player for peripheral nerve injury-induced neuropathic pain. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019864 IgG binding;GO:0031774 leukotriene receptor binding;GO:0019770 IgG receptor activity;GO:0019771 high-affinity IgG receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0038094 Fc-gamma receptor signaling pathway;GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006911 phagocytosis, engulfment;GO:0007166 cell surface receptor signaling pathway;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0B4J2J0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000000000001000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J2J2-1", "uniprot_id": [ { "id": "A0A0B4J2J2_PIG", "url": "https://www.uniprot.org/uniprot/A0A0B4J2J2", "type": "external" } ], "mass": 25703.0, "length": 245, "protein_name": "Pre T-cell antigen receptor alpha", "gene_name": "PTCRA", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PTCRA", "gene_names_refseq": "", "protein_names_uniprotkb": "Pre T-cell antigen receptor alpha; pT-alpha-TCR", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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"synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0B4J2J2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.0000000000010000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4J2J9-1", "uniprot_id": [ { "id": "A0A0B4J2J9_PIG", "url": "https://www.uniprot.org/uniprot/A0A0B4J2J9", "type": "external" } ], "mass": 50052.0, "length": 464, "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC100521529", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100521529", "gene_names_refseq": "", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, 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intellectual disability-severe speech delay-mild dysmorphism syndrome (Disease Ontology:DOID:0111331); pleural tuberculosis (Disease Ontology:DOID:106); hypertension (Disease Ontology:DOID:10763); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); anogenital venereal wart (Disease Ontology:DOID:11168); chlamydia (Disease Ontology:DOID:11263); primary biliary cholangitis (Disease Ontology:DOID:12236); malaria (Disease Ontology:DOID:12365); trichostrongyloidiasis (Disease Ontology:DOID:1255); autistic disorder (Disease Ontology:DOID:12849); Huntington's disease (Disease Ontology:DOID:12858); hypothyroidism (Disease Ontology:DOID:1459); major depressive disorder (Disease Ontology:DOID:1470); congenital heart disease (Disease Ontology:DOID:1682); hepatitis C (Disease Ontology:DOID:1883); hepatitis B (Disease Ontology:DOID:2043); bronchiolitis obliterans (Disease Ontology:DOID:2799); asthma (Disease Ontology:DOID:2841); endometriosis (Disease Ontology:DOID:289); Epstein-Barr virus infectious disease (Disease Ontology:DOID:2938); pulmonary tuberculosis (Disease Ontology:DOID:2957); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321); cervical squamous cell carcinoma (Disease Ontology:DOID:3744); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); multidrug-resistant tuberculosis (Disease Ontology:DOID:401); syphilis (Disease Ontology:DOID:4166); articulation disorder (Disease Ontology:DOID:4186); dyslexia (Disease Ontology:DOID:4428); esophagus adenocarcinoma (Disease Ontology:DOID:4914); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); peritonitis (Disease Ontology:DOID:8283); infectious mononucleosis (Disease Ontology:DOID:8568); cutaneous leishmaniasis (Disease Ontology:DOID:9111); Wiskott-Aldrich syndrome (Disease Ontology:DOID:9169); Barrett's esophagus (Disease Ontology:DOID:9206); colorectal cancer (Disease Ontology:DOID:9256); language disorder (Disease Ontology:DOID:93); type 1 diabetes mellitus (Disease Ontology:DOID:9744); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)", "pathway": " (dme:Dmel_CG43067); (R-DME-8877330)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0035106 operant conditioning;GO:0040011 locomotion;GO:0045433 male courtship behavior, veined wing generated song production;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K6N2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K6N4-1", "uniprot_id": [ { "id": "A0A0B4K6N4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K6N4", "type": "external" } ], "mass": 63447.0, "length": 567, "protein_name": "Tropomodulin, isoform N", "gene_name": "tmod", "organism": "Fruit fly", "refseq_name": "tropomodulin, isoform N", "refseq_ac": [ { "id": "NP_001247372", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247372", "type": "external" } ], "gene_names_uniprotkb": 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159A11T; 15; 3; CG8815; Dmel\\CG8815; Dmel_CG8815; ES2-3; ESTS:159A11T; EY2-9; SIN3A; SIN3; Sin 3A; Sin3a; Sin3; dSin3A; dSin3; l(2)08269; l(2)k02703; l(2)k05415; l(2)k09715; ld; sin3A; sin3a; sin3; sni3", "gene_names_refseq": "159A11T; 27/3; 97/15; CG8815; Dmel\\CG8815; ES2-3; ESTS:159A11T; EY2-9; SIN3A; SIN3; Sin 3A; Sin3A; Sin3a; Sin3; dSin3A; dSin3; l(2)08269; l(2)k02703; l(2)k05415; l(2)k09715; ld; sin3A; sin3a; sin3; sni3", "protein_names_uniprotkb": "Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a", "protein_names_refseq": "CG8815-PG; Sin3A, isoform G; Sin3A-PG; enhancer of GMR-sina 2-3", "tax_id": 7227, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); chromosome 15q24 deletion syndrome (Disease Ontology:DOID:0060395); Huntington's disease (Disease Ontology:DOID:12858); cancer (Disease Ontology:DOID:162); transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (dme:Dmel_CG8815); (R-DME-400206); (R-DME-8936459); (R-DME-9707564); (R-DME-9824594); (R-DME-9825892)", "pathway_count": 6, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. 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BcDNA.GM07659; BcDNA:GH08925; BcDNA:GM07659; CG9847; Dmel\\CG9847; Dmel_CG9847; FKB13; FKBP13; FKBP14; Fkbp13; GM07659; fkbp13; l(2)00734", "gene_names_refseq": "BcDNA.GM07659; BcDNA:GH08925; BcDNA:GM07659; CG9847; Dmel\\CG9847; FKB13; FKBP13; FKBP14; Fkbp13; Fkbp14; GM07659; fkbp13; l(2)00734", "protein_names_uniprotkb": "peptidylprolyl isomerase; 5.2.1.8", "protein_names_refseq": "CG9847-PD; FK506-binding protein 14 ortholog; FK506-binding protein 14, isoform D; Fkbp13; Fkbp14-PD", "tax_id": 7227, "disease": "Ehlers-Danlos syndrome kyphoscoliotic type 2 (Disease Ontology:DOID:0080735)", "pathway": " (dme:Dmel_CG9847)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0012505 endomembrane system", "go_biological_process": "GO:0046716 muscle cell cellular homeostasis;GO:0045747 positive regulation of Notch signaling pathway;GO:0007444 imaginal disc development;GO:0008587 imaginal disc-derived wing margin morphogenesis;GO:0022416 chaeta development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K7C5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7C7-1", "uniprot_id": [ { "id": "A0A0B4K7C7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7C7", "type": "external" } ], "mass": 10318.0, "length": 90, "protein_name": "Seminal fluid protein", "gene_name": "Dmel\\CG43094", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001247249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247249", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43094; CG43094; Dmel_CG43094", "gene_names_refseq": "CG43094; Dmel\\CG43094", "protein_names_uniprotkb": "Seminal fluid protein", "protein_names_refseq": "CG43094-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43094)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K7C7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7E5-1", "uniprot_id": [ { "id": "A0A0B4K7E5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7E5", "type": "external" } ], "mass": 12730.0, "length": 110, "protein_name": "Uncharacterized protein, isoform D", "gene_name": "lincRNA.337", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001246388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246388", "type": "external" } ], "gene_names_uniprotkb": "lincRNA.337; CG43272; Dmel\\CG43272; Dmel_CG43272", "gene_names_refseq": "CG43272; Dmel\\CG43272; lincRNA.337", "protein_names_uniprotkb": "Uncharacterized protein, isoform D", "protein_names_refseq": "CG43272-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43272)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K7E5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7E8-1", "uniprot_id": [ { "id": "A0A0B4K7E8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7E8", "type": "external" } ], "mass": 8245.0, "length": 73, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG43207", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001246476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246476", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43207; CG43207; DMG8-chr2R.33.031; Dmel_CG43207; lincRNA.382", "gene_names_refseq": "CG43207; DMG8-chr2R.33.031; Dmel\\CG43207; lincRNA.382", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43207-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43207)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0B4K7E8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.0000100000000000.0000000000000.000.000", "kg_view_protein": true } ]