[ { "biomarker_canonical_id": "AN6353", "biomarker_id": "AN6353-1", "biomarker": "increased ferroprotein levels", "assessed_biomarker_entity_id": "P02794-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Ferritin heavy chain", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6353-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6354", "biomarker_id": "AN6354-1", "biomarker": "increased TNF\u03b1 levels", "assessed_biomarker_entity_id": "P01375-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Tumor necrosis factor", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 2, "global_evidence_count": 2, "hit_score": 0.5, "record_id": "AN6354-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6360", "biomarker_id": "AN6360-1", "biomarker": "increased calprotectin levels", "assessed_biomarker_entity_id": "P05109-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Protein S100-A8", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "diabetes mellitus (DOID:9351)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6360-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-1", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "breast cancer (DOID:1612)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6372-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-2", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "diabetes mellitus (DOID:9351)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6372-2", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-3", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "skin cancer (DOID:4159)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6372-3", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-4", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "pancreatic cancer (DOID:1793)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6372-4", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-5", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "blood (0000178)", "best_biomarker_role": "diagnostic", "condition": "liver cancer (DOID:3571)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6372-5", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-6", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "saliva (0001836)", "best_biomarker_role": "diagnostic", "condition": "head and neck cancer (DOID:11934)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6372-6", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6372", "biomarker_id": "AN6372-7", "biomarker": "increased IL8 level", "assessed_biomarker_entity_id": "P10145-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Interleukin-8", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 3, "global_evidence_count": 2, "hit_score": 0.6, "record_id": "AN6372-7", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6373", "biomarker_id": "AN6373-1", "biomarker": "increased TNNI3 level", "assessed_biomarker_entity_id": "P19429-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Troponin I, cardiac muscle", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 7, "global_evidence_count": 6, "hit_score": 1.4, "record_id": "AN6373-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6375", "biomarker_id": "AN6375-1", "biomarker": "decreased SERPINC1 level", "assessed_biomarker_entity_id": "P01008-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Antithrombin-III", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 2, "global_evidence_count": 2, "hit_score": 0.5, "record_id": "AN6375-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6376", "biomarker_id": "AN6376-1", "biomarker": "increased SERPINC1 level", "assessed_biomarker_entity_id": "P01008-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Antithrombin-III", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "brain cancer (DOID:1319)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6376-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6377", "biomarker_id": "AN6377-1", "biomarker": "increased FIB level", "assessed_biomarker_entity_id": "P02671-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Fibrinogen alpha chain", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 2, "global_evidence_count": 2, "hit_score": 0.5, "record_id": "AN6377-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6379", "biomarker_id": "AN6379-1", "biomarker": "increased CIT-H3 level", "assessed_biomarker_entity_id": "P68431-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Histone H3.1", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6379-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6379", "biomarker_id": "AN6379-2", "biomarker": "increased CIT-H3 level", "assessed_biomarker_entity_id": "P68431-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Histone H3.1", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "lung cancer (DOID:1324)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6379-2", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6379", "biomarker_id": "AN6379-3", "biomarker": "increased CIT-H3 level", "assessed_biomarker_entity_id": "P68431-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Histone H3.1", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "diabetes mellitus (DOID:9351)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6379-3", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6383", "biomarker_id": "AN6383-1", "biomarker": "increased GGT level", "assessed_biomarker_entity_id": "P19440-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Glutathione hydrolase 1 proenzyme", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "breast cancer (DOID:1612)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6383-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6383", "biomarker_id": "AN6383-2", "biomarker": "increased GGT level", "assessed_biomarker_entity_id": "P19440-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Glutathione hydrolase 1 proenzyme", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "uterine cancer (DOID:363)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6383-2", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6384", "biomarker_id": "AN6384-1", "biomarker": "increased ALT level", "assessed_biomarker_entity_id": "P24298-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Alanine aminotransferase 1", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "breast cancer (DOID:1612)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6384-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6384", "biomarker_id": "AN6384-3", "biomarker": "increased ALT level", "assessed_biomarker_entity_id": "P24298-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Alanine aminotransferase 1", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 7, "global_evidence_count": 8, "hit_score": 1.6, "record_id": "AN6384-3", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6385", "biomarker_id": "AN6385-1", "biomarker": "increased HGF level", "assessed_biomarker_entity_id": "P14210-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Hepatocyte growth factor", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "diabetes mellitus (DOID:9351)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6385-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6400", "biomarker_id": "AN6400-1", "biomarker": "increased NT-proBNP level", "assessed_biomarker_entity_id": "P01160-1; P16860-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Natriuretic peptides A; Natriuretic peptides B", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 2, "component_evidence_count": 2, "global_evidence_count": 2, "hit_score": 0.5, "record_id": "AN6400-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6401", "biomarker_id": "AN6401-1", "biomarker": "increased ALDH5A1 level", "assessed_biomarker_entity_id": "P51649-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Succinate-semialdehyde dehydrogenase, mitochondrial", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 3, "global_evidence_count": 3, "hit_score": 0.7, "record_id": "AN6401-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6402", "biomarker_id": "AN6402-1", "biomarker": "increased CSF1 level", "assessed_biomarker_entity_id": "P09603-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Macrophage colony-stimulating factor 1", "specimen": "blood (0000178)", "best_biomarker_role": "diagnostic", "condition": "breast cancer (DOID:1612)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6402-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6403", "biomarker_id": "AN6403-1", "biomarker": "increased KITLG level", "assessed_biomarker_entity_id": "P21583-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Kit ligand", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 3, "global_evidence_count": 3, "hit_score": 0.7, "record_id": "AN6403-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6404", "biomarker_id": "AN6404-1", "biomarker": "increase KITLG level", "assessed_biomarker_entity_id": "P21583-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Kit ligand", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "breast cancer (DOID:1612)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6404-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6406", "biomarker_id": "AN6406-1", "biomarker": "decreased PF4 level", "assessed_biomarker_entity_id": "P02776-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Platelet factor 4", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6406-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6408", "biomarker_id": "AN6408-1", "biomarker": "increased ENO2 level", "assessed_biomarker_entity_id": "P09104-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Gamma-enolase", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "lung cancer (DOID:1324)", "component_count": 1, "component_evidence_count": 5, "global_evidence_count": 5, "hit_score": 1.1, "record_id": "AN6408-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6416", "biomarker_id": "AN6416-1", "biomarker": "increased LIF", "assessed_biomarker_entity_id": "P15018-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Leukemia inhibitory factor", "specimen": "blood (0000178)", "best_biomarker_role": "monitoring", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6416-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6418", "biomarker_id": "AN6418-1", "biomarker": "increased VEGF-D level", "assessed_biomarker_entity_id": "O43915-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Vascular endothelial growth factor D", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 2, "global_evidence_count": 2, "hit_score": 0.5, "record_id": "AN6418-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6418", "biomarker_id": "AN6418-2", "biomarker": "increased VEGF-D level", "assessed_biomarker_entity_id": "O43915-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Vascular endothelial growth factor D", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "breast cancer (DOID:1612)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6418-2", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6419", "biomarker_id": "AN6419-1", "biomarker": "increased BTK level", "assessed_biomarker_entity_id": "Q06187-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Tyrosine-protein kinase BTK", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 2, "global_evidence_count": 2, "hit_score": 0.5, "record_id": "AN6419-1", "record_type": "biomarker" }, { "biomarker_canonical_id": "AN6420", "biomarker_id": "AN6420-1", "biomarker": "elevated Troponin level", "assessed_biomarker_entity_id": "P19429-1", "assessed_entity_type": "protein", "assessed_biomarker_entity": "Troponin I, cardiac muscle", "specimen": "blood (0000178)", "best_biomarker_role": "prognostic", "condition": "COVID-19 (DOID:0080600)", "component_count": 1, "component_evidence_count": 1, "global_evidence_count": 1, "hit_score": 0.3, "record_id": "AN6420-1", "record_type": "biomarker" } ]