{
    "glytoucan_ac": "G28603RA",
    "species": [
        {
            "taxid": 9606,
            "name": "Homo sapiens",
            "annotation_category": "direct",
            "evidence": [
                {
                    "database": "PubMed",
                    "id": "24766575",
                    "url": "https://glygen.org/publication/PubMed/24766575"
                },
                {
                    "database": "PubMed",
                    "id": "24841998",
                    "url": "https://glygen.org/publication/PubMed/24841998"
                },
                {
                    "database": "PubMed",
                    "id": "29792883",
                    "url": "https://glygen.org/publication/PubMed/29792883"
                },
                {
                    "database": "PubMed",
                    "id": "30093973",
                    "url": "https://glygen.org/publication/PubMed/30093973"
                },
                {
                    "database": "PubMed",
                    "id": "30251656",
                    "url": "https://glygen.org/publication/PubMed/30251656"
                },
                {
                    "database": "GlyGen",
                    "id": "GLY_001408",
                    "url": "https://data.glygen.org/GLY_001408"
                },
                {
                    "database": "UniCarbKB",
                    "id": "GLY_000341",
                    "url": "http://data.glygen.org/GLY_000341"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        },
        {
            "taxid": 10090,
            "name": "Mus musculus",
            "annotation_category": "direct",
            "evidence": [
                {
                    "database": "DOI",
                    "id": "10.1101/2023.09.13.557529",
                    "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                },
                {
                    "database": "GlyGen",
                    "id": "GLY_000889",
                    "url": "https://data.glygen.org/GLY_000889"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "mass": 2378.87,
    "classification": [
        {
            "type": {
                "name": "Other",
                "url": ""
            },
            "subtype": {
                "name": "Other",
                "url": ""
            }
        }
    ],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 0,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 4,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 7,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 1,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 0,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "motifs": [],
    "enzyme": [],
    "biomarkers": [],
    "binding_proteins": [],
    "sites": [
        {
            "start_pos": "180",
            "site_seq": "N",
            "site_lbl": "Asn180",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01857-2",
                    "start_pos": 180,
                    "end_pos": 180,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "24766575",
                            "url": "https://glygen.org/publication/PubMed/24766575"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "24841998",
                            "url": "https://glygen.org/publication/PubMed/24841998"
                        }
                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 1",
                    "gene_name": "IGHG1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 399,
                    "chemical_mass": 43912.0
                }
            ]
        },
        {
            "start_pos": "180",
            "site_seq": "EEQYNSTYR",
            "site_lbl": "Asn180",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01857-2",
                    "start_pos": 180,
                    "end_pos": 180,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "24766575",
                            "url": "https://glygen.org/publication/PubMed/24766575"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "24841998",
                            "url": "https://glygen.org/publication/PubMed/24841998"
                        }
                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 1",
                    "gene_name": "IGHG1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 399,
                    "chemical_mass": 43912.0
                }
            ]
        },
        {
            "start_pos": "180",
            "site_seq": "",
            "site_lbl": "N180",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->SST).",
                    "chr_id": "14",
                    "chr_pos": "105742024",
                    "evidence": [
                        {
                            "id": "P01857",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P01857"
                        },
                        {
                            "id": "rs1241201658",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1241201658"
                        },
                        {
                            "id": "rs1241201658",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1241201658#frequency_tab"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:10534",
                            "name": "stomach cancer",
                            "description": "A gastrointestinal system cancer that is located_in the stomach.",
                            "url": "http://disease-ontology.org/term/DOID:10534",
                            "evidence": [
                                {
                                    "id": "10534",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:10534"
                                },
                                {
                                    "id": "10534",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:10534"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01857-2",
                    "start_pos": 180,
                    "end_pos": 180,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "24766575",
                            "url": "https://glygen.org/publication/PubMed/24766575"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "24841998",
                            "url": "https://glygen.org/publication/PubMed/24841998"
                        }
                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 1",
                    "gene_name": "IGHG1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 399,
                    "chemical_mass": 43912.0
                }
            ]
        },
        {
            "start_pos": "389",
            "site_seq": "GMPNNFSEMPR",
            "site_lbl": "Asn389",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q63912-1",
                    "start_pos": 389,
                    "end_pos": 389,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Oligodendrocyte-myelin glycoprotein",
                    "gene_name": "Omg",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 440,
                    "chemical_mass": 49284.0
                }
            ]
        },
        {
            "start_pos": "389",
            "site_seq": "N",
            "site_lbl": "Asn389",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q63912-1",
                    "start_pos": 389,
                    "end_pos": 389,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Oligodendrocyte-myelin glycoprotein",
                    "gene_name": "Omg",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 440,
                    "chemical_mass": 49284.0
                }
            ]
        },
        {
            "start_pos": "53",
            "site_seq": "AQNDTEPIVLEGK",
            "site_lbl": "Asn53",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8BGU2-1",
                    "start_pos": 53,
                    "end_pos": 53,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Cerebellin-2",
                    "gene_name": "Cbln2",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 224,
                    "chemical_mass": 24051.0
                }
            ]
        },
        {
            "start_pos": "53",
            "site_seq": "N",
            "site_lbl": "Asn53",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8BGU2-1",
                    "start_pos": 53,
                    "end_pos": 53,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Cerebellin-2",
                    "gene_name": "Cbln2",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 224,
                    "chemical_mass": 24051.0
                }
            ]
        },
        {
            "start_pos": "53",
            "site_seq": "",
            "site_lbl": "",
            "residue": "",
            "mutagenesis": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "Q",
                    "comment": "No effect on its ability to form homohexameric or heteromeric complexes with other CBLN family members. Increased interaction with NRXN1 and NRXN3. Total loss of N-glycosylation; when associated with Q-110.",
                    "evidence": [
                        {
                            "database": "UniProtKB",
                            "id": "Q8BGU2",
                            "url": "https://www.uniprot.org/uniprotkb/Q8BGU2"
                        },
                        {
                            "database": "PubMed",
                            "id": "17331201",
                            "url": "https://glygen.org/publication/PubMed/17331201"
                        },
                        {
                            "database": "PubMed",
                            "id": "29782851",
                            "url": "https://glygen.org/publication/PubMed/29782851"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8BGU2-1",
                    "start_pos": 53,
                    "end_pos": 53,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Cerebellin-2",
                    "gene_name": "Cbln2",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 224,
                    "chemical_mass": 24051.0
                }
            ]
        },
        {
            "start_pos": "2190",
            "site_seq": "VGPYANTTR",
            "site_lbl": "Asn2190",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q3UHK6-1",
                    "start_pos": 2190,
                    "end_pos": 2190,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Teneurin-4",
                    "gene_name": "Tenm4",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 2771,
                    "chemical_mass": 308425.0
                }
            ]
        },
        {
            "start_pos": "2190",
            "site_seq": "N",
            "site_lbl": "Asn2190",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q3UHK6-1",
                    "start_pos": 2190,
                    "end_pos": 2190,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Teneurin-4",
                    "gene_name": "Tenm4",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 2771,
                    "chemical_mass": 308425.0
                }
            ]
        },
        {
            "start_pos": "148",
            "site_seq": "ESVHIASYYWSLTGLDIGVNDSSSR",
            "site_lbl": "Asn148",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8BG07-1",
                    "start_pos": 148,
                    "end_pos": 148,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "5'-3' exonuclease PLD4",
                    "gene_name": "Pld4",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 503,
                    "chemical_mass": 56154.0
                }
            ]
        },
        {
            "start_pos": "148",
            "site_seq": "N",
            "site_lbl": "Asn148",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8BG07-1",
                    "start_pos": 148,
                    "end_pos": 148,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "5'-3' exonuclease PLD4",
                    "gene_name": "Pld4",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 503,
                    "chemical_mass": 56154.0
                }
            ]
        },
        {
            "start_pos": "4",
            "site_seq": "MASNNTASIAQAR",
            "site_lbl": "Asn4",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P63213-1",
                    "start_pos": 4,
                    "end_pos": 4,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2",
                    "gene_name": "Gng2",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 71,
                    "chemical_mass": 7850.0
                }
            ]
        },
        {
            "start_pos": "402",
            "site_seq": "DSSEEVNLSQIVPCEPSSEEK",
            "site_lbl": "Asn402",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8R1X6-1",
                    "start_pos": 402,
                    "end_pos": 402,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "GlyGen",
                            "id": "GLY_000889",
                            "url": "https://data.glygen.org/GLY_000889"
                        }
                    ],
                    "protein_name": "Spartin",
                    "gene_name": "Spart",
                    "tax_id": 10090,
                    "tax_name": "Mus musculus",
                    "tax_common_name": "Mouse",
                    "length": 671,
                    "chemical_mass": 72655.0
                }
            ]
        }
    ],
    "record_id": "G28603RA"
}
