{
    "glytoucan_ac": "G10258MC",
    "species": [
        {
            "taxid": 9606,
            "name": "Homo sapiens",
            "annotation_category": "direct",
            "evidence": [
                {
                    "database": "GlyConnect",
                    "id": "3158",
                    "url": "https://glyconnect.expasy.org/browser/structures/3158"
                },
                {
                    "database": "PubMed",
                    "id": "1820200",
                    "url": "https://glygen.org/publication/PubMed/1820200"
                },
                {
                    "database": "PubMed",
                    "id": "1991473",
                    "url": "https://glygen.org/publication/PubMed/1991473"
                },
                {
                    "database": "PubMed",
                    "id": "8026573",
                    "url": "https://glygen.org/publication/PubMed/8026573"
                },
                {
                    "database": "PubMed",
                    "id": "9449027",
                    "url": "https://glygen.org/publication/PubMed/9449027"
                },
                {
                    "database": "UniCarbKB",
                    "id": "GLY_000341",
                    "url": "http://data.glygen.org/GLY_000341"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "mass": 2263.81,
    "classification": [
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Biantennary"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Complex",
                "url": ""
            }
        }
    ],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 0,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 4,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 5,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 2,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 0,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "motifs": [
        {
            "id": "GGM.000001",
            "name": "Type 2 LN",
            "synonym": "N-acetyllactosamine",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 2"
        },
        {
            "id": "GGM.000016",
            "name": "LacdiNAc",
            "synonym": "LDN",
            "keywords": "LacdiNAc; N,N'-diacetyllactosediamine"
        },
        {
            "id": "GGM.000034",
            "name": "3-Sialyl-LN (type 2)",
            "synonym": "",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 2"
        },
        {
            "id": "GGM.000035",
            "name": "6-Sialyl-GalNAc",
            "synonym": "6-Sialyl LN (type 1); 6-Sialyl LN (type 2)",
            "keywords": ""
        },
        {
            "id": "GGM.000050",
            "name": "Sialylated LDN",
            "synonym": "",
            "keywords": "LacdiNAc; N,N'-diacetyllactosediamine"
        }
    ],
    "enzyme": [],
    "biomarkers": [],
    "binding_proteins": [],
    "sites": [
        {
            "start_pos": "102",
            "site_seq": "N",
            "site_lbl": "Asn102",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 102,
                    "end_pos": 102,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "102",
            "site_seq": "VENHTACHCSTCYYHK",
            "site_lbl": "Asn102",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 102,
                    "end_pos": 102,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "76",
            "site_seq": "N",
            "site_lbl": "Asn76",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 76,
                    "end_pos": 76,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "76",
            "site_seq": "NVTSESTCCVAK",
            "site_lbl": "Asn76",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 76,
                    "end_pos": 76,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "76",
            "site_seq": "NVTSESTCCVAK",
            "site_lbl": "",
            "residue": "",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 76,
                    "end_pos": 76,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "76",
            "site_seq": "",
            "site_lbl": "N76",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->IVT).",
                    "chr_id": "6",
                    "chr_pos": "87086296",
                    "evidence": [
                        {
                            "id": "rs373317335",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs373317335"
                        },
                        {
                            "id": "rs373317335",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs373317335"
                        },
                        {
                            "id": "rs373317335",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs373317335"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 76,
                    "end_pos": 76,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "76",
            "site_seq": "",
            "site_lbl": "",
            "residue": "",
            "mutagenesis": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Increases from 1 to 3 the number of FSH binding a single FSHR receptor.",
                    "evidence": [
                        {
                            "database": "UniProtKB",
                            "id": "P01215",
                            "url": "https://www.uniprot.org/uniprotkb/P01215"
                        },
                        {
                            "database": "PubMed",
                            "id": "24692546",
                            "url": "https://glygen.org/publication/PubMed/24692546"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01215-1",
                    "start_pos": 76,
                    "end_pos": 76,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "9449027",
                            "url": "https://glygen.org/publication/PubMed/9449027"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "PubMed",
                            "id": "8026573",
                            "url": "https://glygen.org/publication/PubMed/8026573"
                        },
                        {
                            "database": "PubMed",
                            "id": "1820200",
                            "url": "https://glygen.org/publication/PubMed/1820200"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "194",
                            "url": "https://glyconnect.expasy.org/browser/proteins/194"
                        }
                    ],
                    "protein_name": "Glycoprotein hormones alpha chain",
                    "gene_name": "CGA",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 116,
                    "chemical_mass": 13075.0
                }
            ]
        },
        {
            "start_pos": "50",
            "site_seq": "N",
            "site_lbl": "Asn50",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P01229-1",
                    "start_pos": 50,
                    "end_pos": 50,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "1991473",
                            "url": "https://glygen.org/publication/PubMed/1991473"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "350",
                            "url": "https://glyconnect.expasy.org/browser/proteins/350"
                        }
                    ],
                    "protein_name": "Lutropin subunit beta",
                    "gene_name": "LHB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 141,
                    "chemical_mass": 15345.0
                }
            ]
        }
    ],
    "record_id": "G10258MC"
}
