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                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NIS->TIS).",
                    "chr_id": "14",
                    "chr_pos": "20956127",
                    "evidence": [
                        {
                            "id": "rs1313947014",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1313947014"
                        },
                        {
                            "id": "rs1313947014",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1313947014#frequency_tab"
                        },
                        {
                            "id": "rs1313947014",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1313947014"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P10153-1",
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                    "end_pos": 119,
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8810905",
                            "url": "https://glygen.org/publication/PubMed/8810905"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "7947762",
                            "url": "https://glygen.org/publication/PubMed/7947762"
                        },
                        {
                            "database": "PubMed",
                            "id": "9334252",
                            "url": "https://glygen.org/publication/PubMed/9334252"
                        },
                        {
                            "database": "PubMed",
                            "id": "8358150",
                            "url": "https://glygen.org/publication/PubMed/8358150"
                        }
                    ],
                    "protein_name": "Non-secretory ribonuclease",
                    "gene_name": "RNASE2",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 161,
                    "chemical_mass": 18354.0
                }
            ]
        },
        {
            "start_pos": "44",
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            "site_lbl": "N44",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NMT->IMT).",
                    "chr_id": "14",
                    "chr_pos": "20955902",
                    "evidence": [
                        {
                            "id": "P10153",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P10153"
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                    ],
                    "disease": [
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                            "name": "lung cancer",
                            "description": "A respiratory system cancer that is located_in the lung.",
                            "url": "http://disease-ontology.org/term/DOID:1324",
                            "evidence": [
                                {
                                    "id": "1324",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:1324"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
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                    "end_pos": 44,
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                        {
                            "database": "PubMed",
                            "id": "8358150",
                            "url": "https://glygen.org/publication/PubMed/8358150"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "8810905",
                            "url": "https://glygen.org/publication/PubMed/8810905"
                        },
                        {
                            "database": "PubMed",
                            "id": "9334252",
                            "url": "https://glygen.org/publication/PubMed/9334252"
                        },
                        {
                            "database": "PubMed",
                            "id": "7947762",
                            "url": "https://glygen.org/publication/PubMed/7947762"
                        }
                    ],
                    "protein_name": "Non-secretory ribonuclease",
                    "gene_name": "RNASE2",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 161,
                    "chemical_mass": 18354.0
                }
            ]
        },
        {
            "start_pos": "92",
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            "site_lbl": "N92",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "Y",
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                    "chr_pos": "20956045",
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                        {
                            "id": "P10153",
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                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P10153"
                        }
                    ],
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                                {
                                    "id": "363",
                                    "database": "AGR",
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                            ]
                        }
                    ]
                }
            ],
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                            "id": "8358150",
                            "url": "https://glygen.org/publication/PubMed/8358150"
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
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                            "url": "https://glygen.org/publication/PubMed/7947762"
                        },
                        {
                            "database": "PubMed",
                            "id": "9334252",
                            "url": "https://glygen.org/publication/PubMed/9334252"
                        },
                        {
                            "database": "PubMed",
                            "id": "8810905",
                            "url": "https://glygen.org/publication/PubMed/8810905"
                        }
                    ],
                    "protein_name": "Non-secretory ribonuclease",
                    "gene_name": "RNASE2",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 161,
                    "chemical_mass": 18354.0
                }
            ]
        },
        {
            "start_pos": "323",
            "site_seq": "N",
            "site_lbl": "Asn323",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 323,
                    "end_pos": 323,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "323",
            "site_seq": "SCPACPGSnITIR",
            "site_lbl": "Asn323",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 323,
                    "end_pos": 323,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "483",
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            "site_lbl": "Asn483",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 483,
                    "end_pos": 483,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3ZS0",
                            "url": "https://www.rcsb.org/structure/3ZS0"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9IHF",
                            "url": "https://www.rcsb.org/structure/9IHF"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QE3",
                            "url": "https://www.rcsb.org/structure/9QE3"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QGA",
                            "url": "https://www.rcsb.org/structure/9QGA"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "483",
            "site_seq": "SYnDSVDPR",
            "site_lbl": "Asn483",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 483,
                    "end_pos": 483,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3ZS0",
                            "url": "https://www.rcsb.org/structure/3ZS0"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9IHF",
                            "url": "https://www.rcsb.org/structure/9IHF"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QE3",
                            "url": "https://www.rcsb.org/structure/9QE3"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QGA",
                            "url": "https://www.rcsb.org/structure/9QGA"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "483",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
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                    "end_pos": 483,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3ZS0",
                            "url": "https://www.rcsb.org/structure/3ZS0"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9IHF",
                            "url": "https://www.rcsb.org/structure/9IHF"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QE3",
                            "url": "https://www.rcsb.org/structure/9QE3"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QGA",
                            "url": "https://www.rcsb.org/structure/9QGA"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "729",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 729,
                    "end_pos": 729,
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "729",
            "site_seq": "DFVnCSTLPALNLASWR",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 83869.0
                }
            ]
        },
        {
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            "site_lbl": "N323",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NIT->KIT).",
                    "chr_id": "17",
                    "chr_pos": "58278062",
                    "evidence": [
                        {
                            "id": "P05164",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05164"
                        },
                        {
                            "id": "rs1197536833",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1197536833"
                        },
                        {
                            "id": "rs1197536833",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1197536833"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:1324",
                            "name": "lung cancer",
                            "description": "A respiratory system cancer that is located_in the lung.",
                            "url": "http://disease-ontology.org/term/DOID:1324",
                            "evidence": [
                                {
                                    "id": "1324",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:1324"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NIT->TIT).",
                    "chr_id": "17",
                    "chr_pos": "58278063",
                    "evidence": [
                        {
                            "id": "rs200234386",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200234386"
                        },
                        {
                            "id": "rs200234386",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200234386"
                        },
                        {
                            "id": "rs200234386",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs200234386#frequency_tab"
                        },
                        {
                            "id": "rs200234386",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs200234386"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
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                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "483",
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            "site_lbl": "N483",
            "residue": "",
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                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDS->DDS).",
                    "chr_id": "17",
                    "chr_pos": "58273588",
                    "evidence": [
                        {
                            "id": "rs1970396284",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1970396284"
                        },
                        {
                            "id": "rs1970396284",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1970396284#frequency_tab"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDS->SDS).",
                    "chr_id": "17",
                    "chr_pos": "58273587",
                    "evidence": [
                        {
                            "id": "rs370533452",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs370533452"
                        },
                        {
                            "id": "rs370533452",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs370533452"
                        },
                        {
                            "id": "rs370533452",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs370533452#frequency_tab"
                        },
                        {
                            "id": "rs370533452",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs370533452"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 483,
                    "end_pos": 483,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3ZS0",
                            "url": "https://www.rcsb.org/structure/3ZS0"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9IHF",
                            "url": "https://www.rcsb.org/structure/9IHF"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QE3",
                            "url": "https://www.rcsb.org/structure/9QE3"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "9QGA",
                            "url": "https://www.rcsb.org/structure/9QGA"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "729",
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            "site_lbl": "N729",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NCS->SCS).",
                    "chr_id": "17",
                    "chr_pos": "58270708",
                    "evidence": [
                        {
                            "id": "P05164",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05164"
                        },
                        {
                            "id": "rs754301094",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs754301094"
                        },
                        {
                            "id": "rs754301094",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs754301094"
                        },
                        {
                            "id": "rs754301094",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs754301094"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:363",
                            "name": "uterine cancer",
                            "description": "A female reproductive organ cancer that is located_in the uterus.",
                            "url": "http://disease-ontology.org/term/DOID:363",
                            "evidence": [
                                {
                                    "id": "363",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:363"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05164-1",
                    "start_pos": 729,
                    "end_pos": 729,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Myeloperoxidase",
                    "gene_name": "MPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 745,
                    "chemical_mass": 83869.0
                }
            ]
        },
        {
            "start_pos": "124",
            "site_seq": "N",
            "site_lbl": "Asn124",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P08246-1",
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                    "end_pos": 124,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Neutrophil elastase",
                    "gene_name": "ELANE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 267,
                    "chemical_mass": 28518.0
                }
            ]
        },
        {
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            "site_seq": "N",
            "site_lbl": "Asn173",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P08246-1",
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                    "end_pos": 173,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "6F5M",
                            "url": "https://www.rcsb.org/structure/6F5M"
                        }
                    ],
                    "protein_name": "Neutrophil elastase",
                    "gene_name": "ELANE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 267,
                    "chemical_mass": 28518.0
                }
            ]
        },
        {
            "start_pos": "173",
            "site_seq": "GIASVLQELnVTVVTSLCR",
            "site_lbl": "Asn173",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P08246-1",
                    "start_pos": 173,
                    "end_pos": 173,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "6F5M",
                            "url": "https://www.rcsb.org/structure/6F5M"
                        }
                    ],
                    "protein_name": "Neutrophil elastase",
                    "gene_name": "ELANE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 267,
                    "chemical_mass": 28518.0
                }
            ]
        },
        {
            "start_pos": "124",
            "site_seq": "",
            "site_lbl": "N124",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NGS->DGS).",
                    "chr_id": "19",
                    "chr_pos": "855567",
                    "evidence": [
                        {
                            "id": "rs754547435",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs754547435"
                        },
                        {
                            "id": "rs754547435",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs754547435"
                        },
                        {
                            "id": "rs754547435",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs754547435#frequency_tab"
                        },
                        {
                            "id": "rs754547435",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs754547435"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NGS->KGS).",
                    "chr_id": "19",
                    "chr_pos": "855569",
                    "evidence": [
                        {
                            "id": "rs200595736",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200595736"
                        },
                        {
                            "id": "rs200595736",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200595736"
                        },
                        {
                            "id": "rs200595736",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs200595736#frequency_tab"
                        },
                        {
                            "id": "rs200595736",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs200595736"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
                            "url": "http://disease-ontology.org/term/DOID:0050590",
                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
                            "url": "http://disease-ontology.org/term/DOID:0050590",
                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
                            "url": "http://disease-ontology.org/term/DOID:0050590",
                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
                            "url": "http://disease-ontology.org/term/DOID:0050590",
                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0080625",
                            "name": "severe congenital neutropenia 1",
                            "description": "A severe congenital neutropenia that has_material_basis_in heterozygous mutation in the neutrophil elastase gene on chromosome 19p13.",
                            "url": "http://disease-ontology.org/term/DOID:0080625",
                            "evidence": [
                                {
                                    "id": "202700",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/202700"
                                },
                                {
                                    "id": "0080625",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0080625"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0080625",
                            "name": "severe congenital neutropenia 1",
                            "description": "A severe congenital neutropenia that has_material_basis_in heterozygous mutation in the neutrophil elastase gene on chromosome 19p13.",
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                            "evidence": [
                                {
                                    "id": "202700",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/202700"
                                },
                                {
                                    "id": "0080625",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0080625"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0080625",
                            "name": "severe congenital neutropenia 1",
                            "description": "A severe congenital neutropenia that has_material_basis_in heterozygous mutation in the neutrophil elastase gene on chromosome 19p13.",
                            "url": "http://disease-ontology.org/term/DOID:0080625",
                            "evidence": [
                                {
                                    "id": "202700",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/202700"
                                },
                                {
                                    "id": "0080625",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0080625"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0080625",
                            "name": "severe congenital neutropenia 1",
                            "description": "A severe congenital neutropenia that has_material_basis_in heterozygous mutation in the neutrophil elastase gene on chromosome 19p13.",
                            "url": "http://disease-ontology.org/term/DOID:0080625",
                            "evidence": [
                                {
                                    "id": "202700",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/202700"
                                },
                                {
                                    "id": "0080625",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0080625"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P08246-1",
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                    "end_pos": 124,
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "37639587",
                            "url": "https://glygen.org/publication/PubMed/37639587"
                        },
                        {
                            "database": "TableMaker",
                            "id": "TP6077383",
                            "url": "https://glygen.ccrc.uga.edu/tablemaker/data/TP6077383"
                        }
                    ],
                    "protein_name": "Neutrophil elastase",
                    "gene_name": "ELANE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 267,
                    "chemical_mass": 28518.0
                }
            ]
        },
        {
            "start_pos": "173",
            "site_seq": "",
            "site_lbl": "N173",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->HVT).",
                    "chr_id": "19",
                    "chr_pos": "855714",
                    "evidence": [
                        {
                            "id": "rs1358943684",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1358943684"
                        },
                        {
                            "id": "rs1358943684",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1358943684#frequency_tab"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->KVT).",
                    "chr_id": "19",
                    "chr_pos": "855716",
                    "evidence": [
                        {
                            "id": "rs200393776",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200393776"
                        },
                        {
                            "id": "rs200393776",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200393776"
                        },
                        {
                            "id": "rs200393776",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs200393776#frequency_tab"
                        },
                        {
                            "id": "rs200393776",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs200393776"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->SVT).",
                    "chr_id": "19",
                    "chr_pos": "855715",
                    "evidence": [
                        {
                            "id": "rs748345928",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs748345928"
                        },
                        {
                            "id": "rs748345928",
                            "database": "1000Genomes",
                            "url": "https://www.ensembl.org/homo_sapiens/Variation/Explore?v=rs748345928"
                        },
                        {
                            "id": "rs748345928",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs748345928"
                        },
                        {
                            "id": "rs748345928",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs748345928#frequency_tab"
                        },
                        {
                            "id": "rs748345928",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs748345928"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
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                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
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                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:5339",
                            "name": "cyclic hematopoiesis",
                            "description": "",
                            "url": "http://disease-ontology.org/term/DOID:5339",
                            "evidence": [
                                {
                                    "id": "162800",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/162800"
                                },
                                {
                                    "id": "5339",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:5339"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
                            "url": "http://disease-ontology.org/term/DOID:0050590",
                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
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                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
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                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
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                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050590",
                            "name": "severe congenital neutropenia",
                            "description": "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections.",
                            "url": "http://disease-ontology.org/term/DOID:0050590",
                            "evidence": [
                                {
                                    "id": "0050590",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050590"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0080625",
                            "name": "severe congenital neutropenia 1",
                            "description": "A severe congenital neutropenia that has_material_basis_in heterozygous mutation in the neutrophil elastase gene on chromosome 19p13.",
                            "url": "http://disease-ontology.org/term/DOID:0080625",
                            "evidence": [
                                {
                                    "id": "202700",
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                                {
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                        {
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                                {
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                        {
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                                    "url": "https://www.omim.org/entry/202700"
                                },
                                {
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                        },
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                            "disease_id": "DOID:0080625",
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                                    "id": "202700",
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                                },
                                {
                                    "id": "0080625",
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                                {
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                    ],
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                    ],
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            ]
        },
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            ]
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            ]
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                        {
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                                    "id": "4159",
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            ]
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                        {
                            "id": "rs141614223",
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                        {
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                        {
                            "id": "rs141614223",
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                        {
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                        {
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                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NGS->SGS).",
                    "chr_id": "7",
                    "chr_pos": "99971748",
                    "evidence": [
                        {
                            "id": "rs1454741051",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1454741051"
                        },
                        {
                            "id": "rs1454741051",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1454741051#frequency_tab"
                        },
                        {
                            "id": "rs1454741051",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1454741051"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P25311-1",
                    "start_pos": 112,
                    "end_pos": 112,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "692",
                            "url": "https://glyconnect.expasy.org/browser/proteins/692"
                        }
                    ],
                    "protein_name": "Zinc-alpha-2-glycoprotein",
                    "gene_name": "AZGP1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 298,
                    "chemical_mass": 34259.0
                }
            ]
        },
        {
            "start_pos": "21",
            "site_seq": "N",
            "site_lbl": "Asn21",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P81405-1",
                    "start_pos": 21,
                    "end_pos": 21,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "11180632",
                            "url": "https://glygen.org/publication/PubMed/11180632"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "547",
                            "url": "https://glyconnect.expasy.org/browser/proteins/547"
                        }
                    ],
                    "protein_name": "Saposin-B-Val",
                    "gene_name": "PSAP",
                    "tax_id": 9823,
                    "tax_name": "Sus scrofa",
                    "tax_common_name": "Pig",
                    "length": 80,
                    "chemical_mass": 8949.0
                }
            ]
        },
        {
            "start_pos": "266",
            "site_seq": "N",
            "site_lbl": "Asn266",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "O14917-1",
                    "start_pos": 266,
                    "end_pos": 266,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VFT",
                            "url": "https://www.rcsb.org/structure/6VFT"
                        }
                    ],
                    "protein_name": "Protocadherin-17",
                    "gene_name": "PCDH17",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1159,
                    "chemical_mass": 126229.0
                }
            ]
        },
        {
            "start_pos": "266",
            "site_seq": "",
            "site_lbl": "N266",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NAT->DAT).",
                    "chr_id": "13",
                    "chr_pos": "57633342",
                    "evidence": [
                        {
                            "id": "O14917",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/O14917"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:4159",
                            "name": "skin cancer",
                            "description": "An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells.",
                            "url": "http://disease-ontology.org/term/DOID:4159",
                            "evidence": [
                                {
                                    "id": "4159",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:4159"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NAT->HAT).",
                    "chr_id": "13",
                    "chr_pos": "57633342",
                    "evidence": [
                        {
                            "id": "O14917",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/O14917"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:363",
                            "name": "uterine cancer",
                            "description": "A female reproductive organ cancer that is located_in the uterus.",
                            "url": "http://disease-ontology.org/term/DOID:363",
                            "evidence": [
                                {
                                    "id": "363",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:363"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "O14917-1",
                    "start_pos": 266,
                    "end_pos": 266,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VFT",
                            "url": "https://www.rcsb.org/structure/6VFT"
                        }
                    ],
                    "protein_name": "Protocadherin-17",
                    "gene_name": "PCDH17",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1159,
                    "chemical_mass": 126229.0
                }
            ]
        },
        {
            "start_pos": "616",
            "site_seq": "N",
            "site_lbl": "Asn616",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "O95206-1",
                    "start_pos": 616,
                    "end_pos": 616,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VFV",
                            "url": "https://www.rcsb.org/structure/6VFV"
                        }
                    ],
                    "protein_name": "Protocadherin-8",
                    "gene_name": "PCDH8",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1070,
                    "chemical_mass": 113019.0
                }
            ]
        },
        {
            "start_pos": "240",
            "site_seq": "N",
            "site_lbl": "Asn240",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q15485-1",
                    "start_pos": 240,
                    "end_pos": 240,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "2J1G",
                            "url": "https://www.rcsb.org/structure/2J1G"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "2J3F",
                            "url": "https://www.rcsb.org/structure/2J3F"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "2J3G",
                            "url": "https://www.rcsb.org/structure/2J3G"
                        }
                    ],
                    "protein_name": "Ficolin-2",
                    "gene_name": "FCN2",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 313,
                    "chemical_mass": 34001.0
                }
            ]
        },
        {
            "start_pos": "172",
            "site_seq": "N",
            "site_lbl": "Asn172",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8N6P7-1",
                    "start_pos": 172,
                    "end_pos": 172,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3DGC",
                            "url": "https://www.rcsb.org/structure/3DGC"
                        }
                    ],
                    "protein_name": "Interleukin-22 receptor subunit alpha-1",
                    "gene_name": "IL22RA1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 574,
                    "chemical_mass": 63077.0
                }
            ]
        },
        {
            "start_pos": "172",
            "site_seq": "",
            "site_lbl": "N172",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->TRT).",
                    "chr_id": "1",
                    "chr_pos": "24134227",
                    "evidence": [
                        {
                            "id": "rs1569575664",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1569575664"
                        },
                        {
                            "id": "rs1569575664",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1569575664"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8N6P7-1",
                    "start_pos": 172,
                    "end_pos": 172,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3DGC",
                            "url": "https://www.rcsb.org/structure/3DGC"
                        }
                    ],
                    "protein_name": "Interleukin-22 receptor subunit alpha-1",
                    "gene_name": "IL22RA1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 574,
                    "chemical_mass": 63077.0
                }
            ]
        },
        {
            "start_pos": "75",
            "site_seq": "N",
            "site_lbl": "Asn75",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P29016-1",
                    "start_pos": 75,
                    "end_pos": 75,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "PDB",
                            "id": "3T8X",
                            "url": "https://www.rcsb.org/structure/3T8X"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "3T8X",
                            "url": "https://www.rcsb.org/structure/3T8X"
                        }
                    ],
                    "protein_name": "T-cell surface glycoprotein CD1b",
                    "gene_name": "CD1B",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 333,
                    "chemical_mass": 36939.0
                }
            ]
        },
        {
            "start_pos": "75",
            "site_seq": "",
            "site_lbl": "N75",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NFS->IFS).",
                    "chr_id": "1",
                    "chr_pos": "158330900",
                    "evidence": [
                        {
                            "id": "rs926276534",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs926276534"
                        },
                        {
                            "id": "rs926276534",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs926276534#frequency_tab"
                        },
                        {
                            "id": "rs926276534",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs926276534"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P29016-1",
                    "start_pos": 75,
                    "end_pos": 75,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "PDB",
                            "id": "3T8X",
                            "url": "https://www.rcsb.org/structure/3T8X"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "3T8X",
                            "url": "https://www.rcsb.org/structure/3T8X"
                        }
                    ],
                    "protein_name": "T-cell surface glycoprotein CD1b",
                    "gene_name": "CD1B",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 333,
                    "chemical_mass": 36939.0
                }
            ]
        },
        {
            "start_pos": "297",
            "site_seq": "N",
            "site_lbl": "Asn297",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q13478-1",
                    "start_pos": 297,
                    "end_pos": 297,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3WO3",
                            "url": "https://www.rcsb.org/structure/3WO3"
                        }
                    ],
                    "protein_name": "Interleukin-18 receptor 1",
                    "gene_name": "IL18R1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 541,
                    "chemical_mass": 62304.0
                }
            ]
        },
        {
            "start_pos": "297",
            "site_seq": "",
            "site_lbl": "N297",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Somatic mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NCT->TCT).",
                    "chr_id": "NC_000002.12",
                    "chr_pos": "102386941",
                    "evidence": []
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q13478-1",
                    "start_pos": 297,
                    "end_pos": 297,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3WO3",
                            "url": "https://www.rcsb.org/structure/3WO3"
                        }
                    ],
                    "protein_name": "Interleukin-18 receptor 1",
                    "gene_name": "IL18R1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 541,
                    "chemical_mass": 62304.0
                }
            ]
        },
        {
            "start_pos": "297",
            "site_seq": "",
            "site_lbl": "",
            "residue": "",
            "mutagenesis": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "Q",
                    "comment": "Decreases the affinity for IL18 suggesting that the N-linked glycosylation contributes to ligand recognition.",
                    "evidence": [
                        {
                            "database": "UniProtKB",
                            "id": "Q13478",
                            "url": "https://www.uniprot.org/uniprotkb/Q13478"
                        },
                        {
                            "database": "PubMed",
                            "id": "25500532",
                            "url": "https://glygen.org/publication/PubMed/25500532"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q13478-1",
                    "start_pos": 297,
                    "end_pos": 297,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "3WO3",
                            "url": "https://www.rcsb.org/structure/3WO3"
                        }
                    ],
                    "protein_name": "Interleukin-18 receptor 1",
                    "gene_name": "IL18R1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 541,
                    "chemical_mass": 62304.0
                }
            ]
        },
        {
            "start_pos": "73",
            "site_seq": "N",
            "site_lbl": "Asn73",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q9HBE5-1",
                    "start_pos": 73,
                    "end_pos": 73,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "PDB",
                            "id": "4NZD",
                            "url": "https://www.rcsb.org/structure/4NZD"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "4NZD",
                            "url": "https://www.rcsb.org/structure/4NZD"
                        }
                    ],
                    "protein_name": "Interleukin-21 receptor",
                    "gene_name": "IL21R",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 538,
                    "chemical_mass": 59130.0
                }
            ]
        },
        {
            "start_pos": "73",
            "site_seq": "",
            "site_lbl": "N73",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->DAT).",
                    "chr_id": "16",
                    "chr_pos": "27437552",
                    "evidence": [
                        {
                            "id": "rs1179272510",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1179272510"
                        },
                        {
                            "id": "rs1179272510",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1179272510"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->SAT).",
                    "chr_id": "16",
                    "chr_pos": "27437553",
                    "evidence": [
                        {
                            "id": "rs1362839910",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1362839910"
                        },
                        {
                            "id": "rs1362839910",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1362839910#frequency_tab"
                        },
                        {
                            "id": "rs1362839910",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1362839910"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q9HBE5-1",
                    "start_pos": 73,
                    "end_pos": 73,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "PDB",
                            "id": "4NZD",
                            "url": "https://www.rcsb.org/structure/4NZD"
                        },
                        {
                            "database": "RCSB PDB",
                            "id": "4NZD",
                            "url": "https://www.rcsb.org/structure/4NZD"
                        }
                    ],
                    "protein_name": "Interleukin-21 receptor",
                    "gene_name": "IL21R",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 538,
                    "chemical_mass": 59130.0
                }
            ]
        },
        {
            "start_pos": "445",
            "site_seq": "N",
            "site_lbl": "Asn445",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 445,
                    "end_pos": 445,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9V",
                            "url": "https://www.rcsb.org/structure/6F9V"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "445",
            "site_seq": "VTnDTESDINYLLK",
            "site_lbl": "Asn445",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 445,
                    "end_pos": 445,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9V",
                            "url": "https://www.rcsb.org/structure/6F9V"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "445",
            "site_seq": "IGLLDRVTnDTESDINYLLK",
            "site_lbl": "Asn445",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 445,
                    "end_pos": 445,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9V",
                            "url": "https://www.rcsb.org/structure/6F9V"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "445",
            "site_seq": "VTNDTESDINYLLK",
            "site_lbl": "Asn445",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 445,
                    "end_pos": 445,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9V",
                            "url": "https://www.rcsb.org/structure/6F9V"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "714",
            "site_seq": "N",
            "site_lbl": "Asn714",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 714,
                    "end_pos": 714,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9U",
                            "url": "https://www.rcsb.org/structure/6F9U"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "714",
            "site_seq": "FDVNQLQnTTIK",
            "site_lbl": "Asn714",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 714,
                    "end_pos": 714,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9U",
                            "url": "https://www.rcsb.org/structure/6F9U"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "714",
            "site_seq": "KFDVNQLQnTTIK",
            "site_lbl": "Asn714",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 714,
                    "end_pos": 714,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9U",
                            "url": "https://www.rcsb.org/structure/6F9U"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "714",
            "site_seq": "KFDVNQLQNTTIK",
            "site_lbl": "Asn714",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 714,
                    "end_pos": 714,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9U",
                            "url": "https://www.rcsb.org/structure/6F9U"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "445",
            "site_seq": "",
            "site_lbl": "N445",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->DDT).",
                    "chr_id": "17",
                    "chr_pos": "63482680",
                    "evidence": [
                        {
                            "id": "rs776411660",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs776411660"
                        },
                        {
                            "id": "rs776411660",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs776411660"
                        },
                        {
                            "id": "rs776411660",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs776411660"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->KDT).",
                    "chr_id": "17",
                    "chr_pos": "63482682",
                    "evidence": [
                        {
                            "id": "rs2037090472",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs2037090472"
                        },
                        {
                            "id": "rs2037090472",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs2037090472#frequency_tab"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->SDT).",
                    "chr_id": "17",
                    "chr_pos": "63482681",
                    "evidence": [
                        {
                            "id": "rs1167328695",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1167328695"
                        },
                        {
                            "id": "rs1167328695",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1167328695"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 445,
                    "end_pos": 445,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9V",
                            "url": "https://www.rcsb.org/structure/6F9V"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "714",
            "site_seq": "",
            "site_lbl": "N714",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NTT->KTT).",
                    "chr_id": "17",
                    "chr_pos": "63486640",
                    "evidence": [
                        {
                            "id": "rs778987310",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs778987310"
                        },
                        {
                            "id": "rs778987310",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs778987310"
                        },
                        {
                            "id": "rs778987310",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs778987310#frequency_tab"
                        },
                        {
                            "id": "rs778987310",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs778987310"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 714,
                    "end_pos": 714,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9U",
                            "url": "https://www.rcsb.org/structure/6F9U"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "445",
            "site_seq": "",
            "site_lbl": "",
            "residue": "",
            "mutagenesis": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "In Ndom123456 mutant; abolished dipeptidyl carboxypeptidase activity; when associated with D-318 and D-445. In Ndom1234569 mutant; does not affect dipeptidyl carboxypeptidase activity; when associated with D-318.",
                    "evidence": [
                        {
                            "database": "UniProtKB",
                            "id": "P12821",
                            "url": "https://www.uniprot.org/uniprotkb/P12821"
                        },
                        {
                            "database": "PubMed",
                            "id": "20826823",
                            "url": "https://glygen.org/publication/PubMed/20826823"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P12821-1",
                    "start_pos": 445,
                    "end_pos": 445,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6F9V",
                            "url": "https://www.rcsb.org/structure/6F9V"
                        }
                    ],
                    "protein_name": "Angiotensin-converting enzyme",
                    "gene_name": "ACE",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1306,
                    "chemical_mass": 149715.0
                }
            ]
        },
        {
            "start_pos": "282",
            "site_seq": "N",
            "site_lbl": "Asn282",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P06213-1",
                    "start_pos": 282,
                    "end_pos": 282,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VEP",
                            "url": "https://www.rcsb.org/structure/6VEP"
                        }
                    ],
                    "protein_name": "Insulin receptor",
                    "gene_name": "INSR",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1382,
                    "chemical_mass": 156333.0
                }
            ]
        },
        {
            "start_pos": "282",
            "site_seq": "CVnFSFCQDLHHK",
            "site_lbl": "Asn282",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P06213-1",
                    "start_pos": 282,
                    "end_pos": 282,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VEP",
                            "url": "https://www.rcsb.org/structure/6VEP"
                        }
                    ],
                    "protein_name": "Insulin receptor",
                    "gene_name": "INSR",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1382,
                    "chemical_mass": 156333.0
                }
            ]
        },
        {
            "start_pos": "282",
            "site_seq": "CVNFSFCQDLHHK",
            "site_lbl": "Asn282",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P06213-1",
                    "start_pos": 282,
                    "end_pos": 282,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VEP",
                            "url": "https://www.rcsb.org/structure/6VEP"
                        }
                    ],
                    "protein_name": "Insulin receptor",
                    "gene_name": "INSR",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1382,
                    "chemical_mass": 156333.0
                }
            ]
        },
        {
            "start_pos": "282",
            "site_seq": "",
            "site_lbl": "N282",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NFS->DFS).",
                    "chr_id": "19",
                    "chr_pos": "7184446",
                    "evidence": [
                        {
                            "id": "rs1291755894",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1291755894"
                        },
                        {
                            "id": "rs1291755894",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1291755894#frequency_tab"
                        },
                        {
                            "id": "rs1291755894",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1291755894"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P06213-1",
                    "start_pos": 282,
                    "end_pos": 282,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "6VEP",
                            "url": "https://www.rcsb.org/structure/6VEP"
                        }
                    ],
                    "protein_name": "Insulin receptor",
                    "gene_name": "INSR",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1382,
                    "chemical_mass": 156333.0
                }
            ]
        },
        {
            "start_pos": "544",
            "site_seq": "N",
            "site_lbl": "Asn544",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P28827-1",
                    "start_pos": 544,
                    "end_pos": 544,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "8A17",
                            "url": "https://www.rcsb.org/structure/8A17"
                        }
                    ],
                    "protein_name": "Receptor-type tyrosine-protein phosphatase mu",
                    "gene_name": "PTPRM",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1452,
                    "chemical_mass": 163682.0
                }
            ]
        },
        {
            "start_pos": "544",
            "site_seq": "",
            "site_lbl": "N544",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NET->DET).",
                    "chr_id": "18",
                    "chr_pos": "8085749",
                    "evidence": [
                        {
                            "id": "rs2090399152",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs2090399152"
                        },
                        {
                            "id": "rs2090399152",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs2090399152#frequency_tab"
                        },
                        {
                            "id": "rs2090399152",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs2090399152"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NET->KET).",
                    "chr_id": "NC_000018.10",
                    "chr_pos": "8085751",
                    "evidence": []
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P28827-1",
                    "start_pos": 544,
                    "end_pos": 544,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "8A17",
                            "url": "https://www.rcsb.org/structure/8A17"
                        }
                    ],
                    "protein_name": "Receptor-type tyrosine-protein phosphatase mu",
                    "gene_name": "PTPRM",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 1452,
                    "chemical_mass": 163682.0
                }
            ]
        },
        {
            "start_pos": "281",
            "site_seq": "N",
            "site_lbl": "Asn281",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P27487-1",
                    "start_pos": 281,
                    "end_pos": 281,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "8WKU",
                            "url": "https://www.rcsb.org/structure/8WKU"
                        }
                    ],
                    "protein_name": "Dipeptidyl peptidase 4",
                    "gene_name": "DPP4",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 766,
                    "chemical_mass": 88279.0
                }
            ]
        },
        {
            "start_pos": "281",
            "site_seq": "",
            "site_lbl": "N281",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->HAT).",
                    "chr_id": "2",
                    "chr_pos": "162033587",
                    "evidence": [
                        {
                            "id": "rs200439038",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200439038"
                        },
                        {
                            "id": "rs200439038",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200439038"
                        },
                        {
                            "id": "rs200439038",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs200439038"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->SAT).",
                    "chr_id": "2",
                    "chr_pos": "162033586",
                    "evidence": [
                        {
                            "id": "rs754907411",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs754907411"
                        },
                        {
                            "id": "rs754907411",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs754907411"
                        },
                        {
                            "id": "rs754907411",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs754907411"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P27487-1",
                    "start_pos": 281,
                    "end_pos": 281,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "8WKU",
                            "url": "https://www.rcsb.org/structure/8WKU"
                        }
                    ],
                    "protein_name": "Dipeptidyl peptidase 4",
                    "gene_name": "DPP4",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 766,
                    "chemical_mass": 88279.0
                }
            ]
        },
        {
            "start_pos": "281",
            "site_seq": "",
            "site_lbl": "",
            "residue": "",
            "mutagenesis": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "A",
                    "comment": "Does not inhibit dipeptidyl peptidase activity, interaction with ADA and homodimer formation.",
                    "evidence": [
                        {
                            "database": "UniProtKB",
                            "id": "P27487",
                            "url": "https://www.uniprot.org/uniprotkb/P27487"
                        },
                        {
                            "database": "PubMed",
                            "id": "14691230",
                            "url": "https://glygen.org/publication/PubMed/14691230"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P27487-1",
                    "start_pos": 281,
                    "end_pos": 281,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "8WKU",
                            "url": "https://www.rcsb.org/structure/8WKU"
                        }
                    ],
                    "protein_name": "Dipeptidyl peptidase 4",
                    "gene_name": "DPP4",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 766,
                    "chemical_mass": 88279.0
                }
            ]
        },
        {
            "start_pos": "516",
            "site_seq": "N",
            "site_lbl": "Asn516",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q7L1I2-1",
                    "start_pos": 516,
                    "end_pos": 516,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "9F1R",
                            "url": "https://www.rcsb.org/structure/9F1R"
                        }
                    ],
                    "protein_name": "Synaptic vesicle glycoprotein 2B",
                    "gene_name": "SV2B",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 683,
                    "chemical_mass": 77444.0
                }
            ]
        },
        {
            "start_pos": "516",
            "site_seq": "",
            "site_lbl": "N516",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NST->SST).",
                    "chr_id": "15",
                    "chr_pos": "91284060",
                    "evidence": [
                        {
                            "id": "rs1596787566",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1596787566"
                        },
                        {
                            "id": "rs1596787566",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1596787566"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NST->TST).",
                    "chr_id": "15",
                    "chr_pos": "91284060",
                    "evidence": [
                        {
                            "id": "rs1596787566",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1596787566"
                        },
                        {
                            "id": "rs1596787566",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1596787566"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q7L1I2-1",
                    "start_pos": 516,
                    "end_pos": 516,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "9F1R",
                            "url": "https://www.rcsb.org/structure/9F1R"
                        }
                    ],
                    "protein_name": "Synaptic vesicle glycoprotein 2B",
                    "gene_name": "SV2B",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 683,
                    "chemical_mass": 77444.0
                }
            ]
        },
        {
            "start_pos": "642",
            "site_seq": "N",
            "site_lbl": "Asn642",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P02730-1",
                    "start_pos": 642,
                    "end_pos": 642,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "9MOS",
                            "url": "https://www.rcsb.org/structure/9MOS"
                        }
                    ],
                    "protein_name": "Band 3 anion transport protein",
                    "gene_name": "SLC4A1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 911,
                    "chemical_mass": 101792.0
                }
            ]
        },
        {
            "start_pos": "642",
            "site_seq": "VSnSSAR",
            "site_lbl": "Asn642",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P02730-1",
                    "start_pos": 642,
                    "end_pos": 642,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "9MOS",
                            "url": "https://www.rcsb.org/structure/9MOS"
                        }
                    ],
                    "protein_name": "Band 3 anion transport protein",
                    "gene_name": "SLC4A1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 911,
                    "chemical_mass": 101792.0
                }
            ]
        },
        {
            "start_pos": "642",
            "site_seq": "",
            "site_lbl": "",
            "residue": "",
            "mutagenesis": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Loss of N-glycosylation site.",
                    "evidence": [
                        {
                            "database": "UniProtKB",
                            "id": "P02730",
                            "url": "https://www.uniprot.org/uniprotkb/P02730"
                        },
                        {
                            "database": "PubMed",
                            "id": "24121512",
                            "url": "https://glygen.org/publication/PubMed/24121512"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P02730-1",
                    "start_pos": 642,
                    "end_pos": 642,
                    "residue": "ASN",
                    "evidence": [
                        {
                            "database": "RCSB PDB",
                            "id": "9MOS",
                            "url": "https://www.rcsb.org/structure/9MOS"
                        }
                    ],
                    "protein_name": "Band 3 anion transport protein",
                    "gene_name": "SLC4A1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 911,
                    "chemical_mass": 101792.0
                }
            ]
        }
    ],
    "record_id": "G00395TQ"
}
