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                },
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                        {
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                    ]
                },
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                        {
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                        {
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                        {
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                        {
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                                {
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            ]
        },
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                        {
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        },
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                        {
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            ]
        },
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                        {
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                },
                {
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                        {
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                        {
                            "id": "rs775720629",
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                        {
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            ]
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                        {
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                        {
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                    ],
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                                {
                                    "id": "2531",
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                                    "url": "https://www.alliancegenome.org/disease/DOID:2531"
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                        {
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                    ]
                },
                {
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                            "id": "rs369015684",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs369015684"
                        },
                        {
                            "id": "rs369015684",
                            "database": "TOPMed",
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                        {
                            "id": "rs369015684",
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                    ]
                }
            ],
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                        {
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                    ],
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            ]
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        {
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                {
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                        {
                            "id": "rs61751298",
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                                {
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                                },
                                {
                                    "id": "0111054",
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                            ]
                        },
                        {
                            "disease_id": "DOID:0111054",
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                                {
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                                {
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                            ]
                        },
                        {
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                                {
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                            ]
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                        {
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                                {
                                    "id": "0060573",
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                            ]
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                                {
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                                {
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                                {
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                                },
                                {
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                        {
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                        {
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                },
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            ]
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        {
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                            "id": "P01871",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P01871"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:10534",
                            "name": "stomach cancer",
                            "description": "A gastrointestinal system cancer that is located_in the stomach.",
                            "url": "http://disease-ontology.org/term/DOID:10534",
                            "evidence": [
                                {
                                    "id": "10534",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:10534"
                                },
                                {
                                    "id": "10534",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:10534"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NAS->HAS).",
                    "chr_id": "14",
                    "chr_pos": "105855504",
                    "evidence": [
                        {
                            "id": "P01871",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P01871"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:363",
                            "name": "uterine cancer",
                            "description": "A female reproductive organ cancer that is located_in the uterus.",
                            "url": "http://disease-ontology.org/term/DOID:363",
                            "evidence": [
                                {
                                    "id": "363",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:363"
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                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "Y",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAS->YAS).",
                    "chr_id": "14",
                    "chr_pos": "105855504",
                    "evidence": [
                        {
                            "id": "rs1258657913",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1258657913"
                        },
                        {
                            "id": "rs1258657913",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1258657913#frequency_tab"
                        },
                        {
                            "id": "rs1258657913",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1258657913"
                        }
                    ]
                }
            ],
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                {
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                    "end_pos": 209,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        },
                        {
                            "database": "PubMed",
                            "id": "24841998",
                            "url": "https://glygen.org/publication/PubMed/24841998"
                        },
                        {
                            "database": "PubMed",
                            "id": "24766575",
                            "url": "https://glygen.org/publication/PubMed/24766575"
                        },
                        {
                            "database": "PubMed",
                            "id": "30659065",
                            "url": "https://glygen.org/publication/PubMed/30659065"
                        },
                        {
                            "database": "GPTwiki",
                            "id": "G08293MJ",
                            "url": "https://edwardslab.bmcb.georgetown.edu/gptwiki/G08293MJ"
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                    ],
                    "protein_name": "Immunoglobulin heavy constant mu",
                    "gene_name": "IGHM",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 51924.0
                }
            ]
        },
        {
            "start_pos": "272",
            "site_seq": "",
            "site_lbl": "N272",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NIS->TIS).",
                    "chr_id": "14",
                    "chr_pos": "105855069",
                    "evidence": [
                        {
                            "id": "rs2142901381",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs2142901381"
                        },
                        {
                            "id": "rs2142901381",
                            "database": "ENSEMBL",
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                    ]
                }
            ],
            "glycoprotein": [
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                    "evidence": [
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                            "database": "PubMed",
                            "id": "30659065",
                            "url": "https://glygen.org/publication/PubMed/30659065"
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                        {
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                    ],
                    "protein_name": "Immunoglobulin heavy constant mu",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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            ]
        },
        {
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                        {
                            "id": "rs1229938382",
                            "database": "TOPMed",
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            ],
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                            "database": "PubMed",
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                        {
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                        {
                            "database": "PubMed",
                            "id": "24766575",
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                        {
                            "database": "PubMed",
                            "id": "30659065",
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                    ],
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            ]
        },
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                        },
                        {
                            "database": "GPTwiki",
                            "id": "G08293MJ",
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                    ],
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            ]
        },
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                    ],
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            ]
        },
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                    ],
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            ]
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                    ]
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            ],
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                                {
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                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->KST).",
                    "chr_id": "2",
                    "chr_pos": "21006635",
                    "evidence": [
                        {
                            "id": "P04114",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P04114"
                        },
                        {
                            "id": "rs771372599",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs771372599"
                        },
                        {
                            "id": "rs771372599",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs771372599"
                        },
                        {
                            "id": "rs771372599",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs771372599#frequency_tab"
                        },
                        {
                            "id": "rs771372599",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs771372599"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:1612",
                            "name": "breast cancer",
                            "description": "An organ system cancer that originates in the mammary gland.",
                            "url": "http://disease-ontology.org/term/DOID:1612",
                            "evidence": [
                                {
                                    "id": "1612",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:1612"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:2394",
                            "name": "ovarian cancer",
                            "description": "A female reproductive organ cancer that is located_in the ovary.",
                            "url": "http://disease-ontology.org/term/DOID:2394",
                            "evidence": [
                                {
                                    "id": "2394",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2394"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NST->SST).",
                    "chr_id": "2",
                    "chr_pos": "21006636",
                    "evidence": [
                        {
                            "id": "rs773958267",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773958267"
                        },
                        {
                            "id": "rs773958267",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773958267"
                        },
                        {
                            "id": "rs773958267",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773958267"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "end_pos": 3411,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3465",
            "site_seq": "",
            "site_lbl": "N3465",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->DSS).",
                    "chr_id": "2",
                    "chr_pos": "21006475",
                    "evidence": [
                        {
                            "id": "rs751227728",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs751227728"
                        },
                        {
                            "id": "rs751227728",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs751227728"
                        },
                        {
                            "id": "rs751227728",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs751227728"
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                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->SSS).",
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                    "chr_pos": "21006474",
                    "evidence": [
                        {
                            "id": "rs1663141372",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1663141372"
                        },
                        {
                            "id": "rs1663141372",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1663141372"
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                    ]
                }
            ],
            "glycoprotein": [
                {
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                    "residue": "asn",
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                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
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                    ],
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                    "gene_name": "APOB",
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                    "tax_common_name": "Human",
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            ]
        },
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                            "url": "https://glygen.org/publication/PubMed/23345538"
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                        {
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                            "url": "http://data.glygen.org/GLY_000040"
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                    ],
                    "protein_name": "SPARC",
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                    "tax_common_name": "Human",
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            ]
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                        },
                        {
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                            "id": "GLY_000040",
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                    ],
                    "protein_name": "SPARC",
                    "gene_name": "SPARC",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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            ]
        },
        {
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                            "url": "https://glygen.org/publication/PubMed/23345538"
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                        {
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                    ],
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        {
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            ]
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            ]
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        {
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                        {
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                    ],
                    "protein_name": "Plasma protease C1 inhibitor",
                    "gene_name": "SERPING1",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 55154.0
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            ]
        },
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                        {
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                        {
                            "id": "rs776553402",
                            "database": "gnomAD",
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                            "database": "GPTwiki",
                            "id": "G08293MJ",
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                    ],
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                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 3",
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                    "chemical_mass": 49093.0
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            ]
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                        {
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                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 3",
                    "gene_name": "IGHG3",
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            ]
        },
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                        {
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                            "id": "GLY_000040",
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                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 3",
                    "gene_name": "IGHG3",
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                    "chemical_mass": 49093.0
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            ]
        },
        {
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                        {
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                    ],
                    "protein_name": "Immunoglobulin heavy constant gamma 3",
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                    "chemical_mass": 49093.0
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            ]
        },
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                    "tax_name": "Homo sapiens",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
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                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                    "tax_name": "Homo sapiens",
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                    "chemical_mass": 65750.0
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            ]
        },
        {
            "start_pos": "177",
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                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "residue": "asn",
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                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
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                {
                    "uniprot_canonical_ac": "P05156-1",
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                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
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                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
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            "site_seq": "LSDLSInSTECLHVHCR",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                            "database": "PubMed",
                            "id": "29671580",
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                    "tax_name": "Homo sapiens",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
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                    "uniprot_canonical_ac": "P05156-1",
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                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
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                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                }
            ]
        },
        {
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                            "url": "https://glygen.org/publication/PubMed/29671580"
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                        {
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                    ],
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                }
            ]
        },
        {
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                    "uniprot_canonical_ac": "P05156-1",
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
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                    ],
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            ]
        },
        {
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                        },
                        {
                            "database": "UniCarbKB",
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                            "url": "http://data.glygen.org/GLY_000040"
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                    ],
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                    "gene_name": "CFI",
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            ]
        },
        {
            "start_pos": "177",
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            "site_lbl": "N177",
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                {
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                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->HST).",
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                    "chr_pos": "109761646",
                    "evidence": [
                        {
                            "id": "P05156",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
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                    ],
                    "disease": [
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                            "disease_id": "DOID:9256",
                            "name": "colorectal cancer",
                            "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.",
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                            "evidence": [
                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
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                            ]
                        }
                    ]
                },
                {
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                    "sequence_org": "N",
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                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->IST).",
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                    "chr_pos": "109761645",
                    "evidence": [
                        {
                            "id": "P05156",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
                        },
                        {
                            "id": "rs753060374",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs753060374"
                        },
                        {
                            "id": "rs753060374",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs753060374"
                        },
                        {
                            "id": "rs753060374",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs753060374#frequency_tab"
                        },
                        {
                            "id": "rs753060374",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs753060374"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:2531",
                            "name": "hematologic cancer",
                            "description": "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.",
                            "url": "http://disease-ontology.org/term/DOID:2531",
                            "evidence": [
                                {
                                    "id": "2531",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2531"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
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                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
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                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 177,
                    "end_pos": 177,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "177",
            "site_seq": "N",
            "site_lbl": "Asn177",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "end_pos": 177,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "177",
            "site_seq": "LSDLSInSTECLHVHCR",
            "site_lbl": "Asn177",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 177,
                    "end_pos": 177,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "177",
            "site_seq": "LSDLSINSTECLHVHCR",
            "site_lbl": "Asn177",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "end_pos": 177,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "177",
            "site_seq": "",
            "site_lbl": "N177",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->HST).",
                    "chr_id": "4",
                    "chr_pos": "109761646",
                    "evidence": [
                        {
                            "id": "P05156",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:9256",
                            "name": "colorectal cancer",
                            "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.",
                            "url": "http://disease-ontology.org/term/DOID:9256",
                            "evidence": [
                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->IST).",
                    "chr_id": "4",
                    "chr_pos": "109761645",
                    "evidence": [
                        {
                            "id": "P05156",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
                        },
                        {
                            "id": "rs753060374",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs753060374"
                        },
                        {
                            "id": "rs753060374",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs753060374"
                        },
                        {
                            "id": "rs753060374",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs753060374#frequency_tab"
                        },
                        {
                            "id": "rs753060374",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs753060374"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:2531",
                            "name": "hematologic cancer",
                            "description": "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.",
                            "url": "http://disease-ontology.org/term/DOID:2531",
                            "evidence": [
                                {
                                    "id": "2531",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2531"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
                            "url": "http://disease-ontology.org/term/DOID:0110025",
                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "end_pos": 177,
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Complement factor I",
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                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "249",
            "site_seq": "N",
            "site_lbl": "Asn249",
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                    ]
                },
                {
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                    ],
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                    "tax_common_name": "Human",
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            ]
        },
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                {
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                        {
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                    ],
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            ]
        },
        {
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                {
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            ]
        },
        {
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                {
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            ]
        },
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                        {
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                        {
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                        {
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                        {
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                    ]
                },
                {
                    "weight": 100,
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            ]
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                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1244707129"
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                        {
                            "id": "rs1244707129",
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                    ]
                },
                {
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                        {
                            "id": "rs770113523",
                            "database": "gnomAD",
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                    ]
                },
                {
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                        {
                            "id": "rs556158119",
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                        {
                            "id": "rs556158119",
                            "database": "ExAC",
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                        {
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                        {
                            "id": "rs556158119",
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                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
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                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NGS->YGS).",
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                        {
                            "id": "rs1167553984",
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                    ]
                }
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                        {
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            ]
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                        {
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                        {
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                        {
                            "id": "rs750855229",
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                    ],
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                    ],
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                    "chemical_mass": 32903.0
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            ]
        },
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                    ],
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            ]
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            ]
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                    ],
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            ]
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                    ],
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            ]
        },
        {
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                    ],
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        },
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                    ]
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                    ]
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                    ],
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                    ]
                },
                {
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            ]
        },
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                    ],
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            ]
        },
        {
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                    ],
                    "protein_name": "Lysosome-associated membrane glycoprotein 2",
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