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                        {
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                        {
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                    ],
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                                },
                                {
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                        },
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                                {
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                    ]
                },
                {
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                        {
                            "id": "rs1168175119",
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                                {
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                                {
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                        {
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                        {
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                                    "id": "363",
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                                {
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                                {
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                                {
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                                {
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                        {
                            "id": "rs768650910",
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                        {
                            "id": "rs768650910",
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                        {
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                        {
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                    ]
                },
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                        {
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                        {
                            "id": "rs576328100",
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                        {
                            "id": "rs576328100",
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                    "chr_pos": "215404622",
                    "evidence": [
                        {
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                            "database": "dbSNP",
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                        },
                        {
                            "id": "rs145838840",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs145838840"
                        },
                        {
                            "id": "rs145838840",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs145838840#frequency_tab"
                        },
                        {
                            "id": "rs145838840",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs145838840"
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                    ],
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                            "url": "http://disease-ontology.org/term/DOID:0112297",
                            "evidence": [
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
                                },
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0112297",
                            "name": "spondylometaphyseal dysplasia corner fracture type",
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                            "evidence": [
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
                                },
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
                                }
                            ]
                        },
                        {
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                            "evidence": [
                                {
                                    "id": "0112297",
                                    "database": "AGR",
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                                },
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0112297",
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                            "evidence": [
                                {
                                    "id": "0112297",
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                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
                                },
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0112297",
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                                {
                                    "id": "0112297",
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                                },
                                {
                                    "id": "0112297",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0112297"
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                            ]
                        }
                    ]
                },
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                    "sequence_org": "N",
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                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NET->YET).",
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                    "chr_pos": "215404623",
                    "evidence": [
                        {
                            "id": "rs768650910",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs768650910"
                        },
                        {
                            "id": "rs768650910",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs768650910"
                        },
                        {
                            "id": "rs768650910",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs768650910"
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                    ]
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                {
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                            "database": "PubMed",
                            "id": "24279413",
                            "url": "https://glygen.org/publication/PubMed/24279413"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "161",
                            "url": "https://glyconnect.expasy.org/browser/proteins/161"
                        },
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
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                    ],
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            ]
        },
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                {
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                    "sequence_org": "N",
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                        },
                        {
                            "id": "rs1157885400",
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                        {
                            "id": "rs1157885400",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1157885400"
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                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
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                    "chr_pos": "215394618",
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                        {
                            "id": "P02751",
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                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P02751"
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                    ],
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                        {
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                            "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.",
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                            "evidence": [
                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
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                        {
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                    ],
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            ]
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                    "sequence_org": "N",
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                    "evidence": [
                        {
                            "id": "rs528350304",
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                        {
                            "id": "rs528350304",
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                        {
                            "id": "rs528350304",
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                        {
                            "id": "rs528350304",
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                        {
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                        {
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                        {
                            "id": "rs749189506",
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                    ]
                },
                {
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                        {
                            "id": "rs138144264",
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                    ]
                },
                {
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                    "sequence_org": "N",
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                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NCT->SCT).",
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                            "id": "rs576328100",
                            "database": "dbSNP",
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                        {
                            "id": "rs576328100",
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                        {
                            "id": "rs576328100",
                            "database": "ExAC",
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                        {
                            "id": "rs576328100",
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                        {
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                        {
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                    ],
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                            ]
                        },
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                    ],
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        },
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                    ],
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                        {
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                    ]
                },
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                        {
                            "id": "rs777042846",
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                        {
                            "id": "rs777042846",
                            "database": "gnomAD",
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                    ]
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                        {
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                                {
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                            ]
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                    ]
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                        {
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                        {
                            "id": "rs61729548",
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                                {
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                                    "database": "AGR",
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                        {
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                        {
                            "id": "rs542942614",
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                        {
                            "id": "rs542942614",
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                        {
                            "id": "rs542942614",
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                            "id": "rs542942614",
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                                {
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                                {
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                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "2239",
            "site_seq": "",
            "site_lbl": "N2239",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NKS->KKS).",
                    "chr_id": "2",
                    "chr_pos": "21010151",
                    "evidence": [
                        {
                            "id": "P04114",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P04114"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:9256",
                            "name": "colorectal cancer",
                            "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.",
                            "url": "http://disease-ontology.org/term/DOID:9256",
                            "evidence": [
                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 2239,
                    "end_pos": 2239,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "2982",
            "site_seq": "",
            "site_lbl": "N2982",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NFS->HFS).",
                    "chr_id": "2",
                    "chr_pos": "21007924",
                    "evidence": [
                        {
                            "id": "rs1460637587",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1460637587"
                        },
                        {
                            "id": "rs1460637587",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1460637587"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:0111062",
                            "name": "familial hypobetalipoproteinemia 1",
                            "description": "A hypobetalipoproteinemia that has_material_basis_in mutation in the APOB gene on chromosome 2p24.",
                            "url": "http://disease-ontology.org/term/DOID:0111062",
                            "evidence": [
                                {
                                    "id": "615558",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615558"
                                },
                                {
                                    "id": "0111062",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0111062"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0111062",
                            "name": "familial hypobetalipoproteinemia 1",
                            "description": "A hypobetalipoproteinemia that has_material_basis_in mutation in the APOB gene on chromosome 2p24.",
                            "url": "http://disease-ontology.org/term/DOID:0111062",
                            "evidence": [
                                {
                                    "id": "615558",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615558"
                                },
                                {
                                    "id": "0111062",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0111062"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NFS->KFS).",
                    "chr_id": "2",
                    "chr_pos": "21007922",
                    "evidence": [
                        {
                            "id": "rs775661185",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs775661185"
                        },
                        {
                            "id": "rs775661185",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs775661185"
                        },
                        {
                            "id": "rs775661185",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs775661185"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 2982,
                    "end_pos": 2982,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3224",
            "site_seq": "",
            "site_lbl": "N3224",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NET->SET).",
                    "chr_id": "2",
                    "chr_pos": "21007197",
                    "evidence": [
                        {
                            "id": "rs1663168031",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1663168031"
                        },
                        {
                            "id": "rs1663168031",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1663168031"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 3224,
                    "end_pos": 3224,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3411",
            "site_seq": "",
            "site_lbl": "N3411",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->KST).",
                    "chr_id": "2",
                    "chr_pos": "21006635",
                    "evidence": [
                        {
                            "id": "P04114",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P04114"
                        },
                        {
                            "id": "rs771372599",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs771372599"
                        },
                        {
                            "id": "rs771372599",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs771372599"
                        },
                        {
                            "id": "rs771372599",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs771372599#frequency_tab"
                        },
                        {
                            "id": "rs771372599",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs771372599"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:1612",
                            "name": "breast cancer",
                            "description": "An organ system cancer that originates in the mammary gland.",
                            "url": "http://disease-ontology.org/term/DOID:1612",
                            "evidence": [
                                {
                                    "id": "1612",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:1612"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:2394",
                            "name": "ovarian cancer",
                            "description": "A female reproductive organ cancer that is located_in the ovary.",
                            "url": "http://disease-ontology.org/term/DOID:2394",
                            "evidence": [
                                {
                                    "id": "2394",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2394"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NST->SST).",
                    "chr_id": "2",
                    "chr_pos": "21006636",
                    "evidence": [
                        {
                            "id": "rs773958267",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773958267"
                        },
                        {
                            "id": "rs773958267",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773958267"
                        },
                        {
                            "id": "rs773958267",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773958267"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 3411,
                    "end_pos": 3411,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3465",
            "site_seq": "",
            "site_lbl": "N3465",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->DSS).",
                    "chr_id": "2",
                    "chr_pos": "21006475",
                    "evidence": [
                        {
                            "id": "rs751227728",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs751227728"
                        },
                        {
                            "id": "rs751227728",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs751227728"
                        },
                        {
                            "id": "rs751227728",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs751227728"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->SSS).",
                    "chr_id": "2",
                    "chr_pos": "21006474",
                    "evidence": [
                        {
                            "id": "rs1663141372",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1663141372"
                        },
                        {
                            "id": "rs1663141372",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1663141372"
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                    ]
                }
            ],
            "glycoprotein": [
                {
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
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                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
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            ]
        },
        {
            "start_pos": "3895",
            "site_seq": "",
            "site_lbl": "N3895",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->HAT).",
                    "chr_id": "2",
                    "chr_pos": "21005185",
                    "evidence": [
                        {
                            "id": "rs2103350346",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs2103350346"
                        },
                        {
                            "id": "rs2103350346",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs2103350346"
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                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->SAT).",
                    "chr_id": "2",
                    "chr_pos": "21005184",
                    "evidence": [
                        {
                            "id": "rs1434488061",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1434488061"
                        },
                        {
                            "id": "rs1434488061",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1434488061#frequency_tab"
                        },
                        {
                            "id": "rs1434488061",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1434488061"
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                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "983",
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            "site_lbl": "N983",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAS->SAS).",
                    "chr_id": "2",
                    "chr_pos": "21019774",
                    "evidence": [
                        {
                            "id": "rs1407756735",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1407756735"
                        },
                        {
                            "id": "rs1407756735",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1407756735"
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                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "Y",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAS->YAS).",
                    "chr_id": "2",
                    "chr_pos": "21019775",
                    "evidence": [
                        {
                            "id": "rs767190489",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs767190489"
                        },
                        {
                            "id": "rs767190489",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs767190489"
                        },
                        {
                            "id": "rs767190489",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs767190489"
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                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "end_pos": 983,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
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            ]
        },
        {
            "start_pos": "1523",
            "site_seq": "N",
            "site_lbl": "Asn1523",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 1523,
                    "end_pos": 1523,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
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                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "1523",
            "site_seq": "FnSSYLQGTNQITGR",
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            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "2239",
            "site_seq": "",
            "site_lbl": "N2239",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NKS->KKS).",
                    "chr_id": "2",
                    "chr_pos": "21010151",
                    "evidence": [
                        {
                            "id": "P04114",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P04114"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:9256",
                            "name": "colorectal cancer",
                            "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.",
                            "url": "http://disease-ontology.org/term/DOID:9256",
                            "evidence": [
                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 2239,
                    "end_pos": 2239,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "2982",
            "site_seq": "",
            "site_lbl": "N2982",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NFS->HFS).",
                    "chr_id": "2",
                    "chr_pos": "21007924",
                    "evidence": [
                        {
                            "id": "rs1460637587",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1460637587"
                        },
                        {
                            "id": "rs1460637587",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1460637587"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:0111062",
                            "name": "familial hypobetalipoproteinemia 1",
                            "description": "A hypobetalipoproteinemia that has_material_basis_in mutation in the APOB gene on chromosome 2p24.",
                            "url": "http://disease-ontology.org/term/DOID:0111062",
                            "evidence": [
                                {
                                    "id": "615558",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615558"
                                },
                                {
                                    "id": "0111062",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0111062"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0111062",
                            "name": "familial hypobetalipoproteinemia 1",
                            "description": "A hypobetalipoproteinemia that has_material_basis_in mutation in the APOB gene on chromosome 2p24.",
                            "url": "http://disease-ontology.org/term/DOID:0111062",
                            "evidence": [
                                {
                                    "id": "615558",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615558"
                                },
                                {
                                    "id": "0111062",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0111062"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NFS->KFS).",
                    "chr_id": "2",
                    "chr_pos": "21007922",
                    "evidence": [
                        {
                            "id": "rs775661185",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs775661185"
                        },
                        {
                            "id": "rs775661185",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs775661185"
                        },
                        {
                            "id": "rs775661185",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs775661185"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 2982,
                    "end_pos": 2982,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3224",
            "site_seq": "",
            "site_lbl": "N3224",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NET->SET).",
                    "chr_id": "2",
                    "chr_pos": "21007197",
                    "evidence": [
                        {
                            "id": "rs1663168031",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1663168031"
                        },
                        {
                            "id": "rs1663168031",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1663168031"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 3224,
                    "end_pos": 3224,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3411",
            "site_seq": "",
            "site_lbl": "N3411",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->KST).",
                    "chr_id": "2",
                    "chr_pos": "21006635",
                    "evidence": [
                        {
                            "id": "P04114",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P04114"
                        },
                        {
                            "id": "rs771372599",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs771372599"
                        },
                        {
                            "id": "rs771372599",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs771372599"
                        },
                        {
                            "id": "rs771372599",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs771372599#frequency_tab"
                        },
                        {
                            "id": "rs771372599",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs771372599"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:1612",
                            "name": "breast cancer",
                            "description": "An organ system cancer that originates in the mammary gland.",
                            "url": "http://disease-ontology.org/term/DOID:1612",
                            "evidence": [
                                {
                                    "id": "1612",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:1612"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:2394",
                            "name": "ovarian cancer",
                            "description": "A female reproductive organ cancer that is located_in the ovary.",
                            "url": "http://disease-ontology.org/term/DOID:2394",
                            "evidence": [
                                {
                                    "id": "2394",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2394"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NST->SST).",
                    "chr_id": "2",
                    "chr_pos": "21006636",
                    "evidence": [
                        {
                            "id": "rs773958267",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773958267"
                        },
                        {
                            "id": "rs773958267",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773958267"
                        },
                        {
                            "id": "rs773958267",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773958267"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
                    "start_pos": 3411,
                    "end_pos": 3411,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3465",
            "site_seq": "",
            "site_lbl": "N3465",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->DSS).",
                    "chr_id": "2",
                    "chr_pos": "21006475",
                    "evidence": [
                        {
                            "id": "rs751227728",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs751227728"
                        },
                        {
                            "id": "rs751227728",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs751227728"
                        },
                        {
                            "id": "rs751227728",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs751227728"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->SSS).",
                    "chr_id": "2",
                    "chr_pos": "21006474",
                    "evidence": [
                        {
                            "id": "rs1663141372",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1663141372"
                        },
                        {
                            "id": "rs1663141372",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs1663141372"
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                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "end_pos": 3465,
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        },
                        {
                            "database": "PubMed",
                            "id": "32125861",
                            "url": "https://glygen.org/publication/PubMed/32125861"
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                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "3895",
            "site_seq": "",
            "site_lbl": "N3895",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "H",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->HAT).",
                    "chr_id": "2",
                    "chr_pos": "21005185",
                    "evidence": [
                        {
                            "id": "rs2103350346",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs2103350346"
                        },
                        {
                            "id": "rs2103350346",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs2103350346"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->SAT).",
                    "chr_id": "2",
                    "chr_pos": "21005184",
                    "evidence": [
                        {
                            "id": "rs1434488061",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1434488061"
                        },
                        {
                            "id": "rs1434488061",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1434488061#frequency_tab"
                        },
                        {
                            "id": "rs1434488061",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1434488061"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
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                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "983",
            "site_seq": "",
            "site_lbl": "N983",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAS->SAS).",
                    "chr_id": "2",
                    "chr_pos": "21019774",
                    "evidence": [
                        {
                            "id": "rs1407756735",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1407756735"
                        },
                        {
                            "id": "rs1407756735",
                            "database": "gnomAD",
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                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "Y",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAS->YAS).",
                    "chr_id": "2",
                    "chr_pos": "21019775",
                    "evidence": [
                        {
                            "id": "rs767190489",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs767190489"
                        },
                        {
                            "id": "rs767190489",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs767190489"
                        },
                        {
                            "id": "rs767190489",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs767190489"
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                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04114-1",
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                    "end_pos": 983,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "57",
                            "url": "https://glyconnect.expasy.org/browser/proteins/57"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        }
                    ],
                    "protein_name": "Apolipoprotein B-100",
                    "gene_name": "APOB",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 4563,
                    "chemical_mass": 515545.0
                }
            ]
        },
        {
            "start_pos": "857",
            "site_seq": "WnCTDHVCDATCSTIGMAHYLTFDGLK",
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            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04275-1",
                    "start_pos": 857,
                    "end_pos": 857,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "627",
                            "url": "https://glyconnect.expasy.org/browser/proteins/627"
                        }
                    ],
                    "protein_name": "von Willebrand factor",
                    "gene_name": "VWF",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 2813,
                    "chemical_mass": 309265.0
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            ]
        },
        {
            "start_pos": "857",
            "site_seq": "N",
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            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P04275-1",
                    "start_pos": 857,
                    "end_pos": 857,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
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                            "id": "742",
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            ]
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                        {
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                    ],
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            ]
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                        {
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                    ],
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                    ],
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            ]
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        {
            "start_pos": "70",
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                        {
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                    ],
                    "protein_name": "Complement factor I",
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            ]
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                    ],
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            ]
        },
        {
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                    ],
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                        }
                    ]
                },
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                        {
                            "id": "rs753060374",
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                        {
                            "id": "rs753060374",
                            "database": "TOPMed",
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                        },
                        {
                            "id": "rs753060374",
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                    ],
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                            ]
                        },
                        {
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                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
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                                    "id": "615439",
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                                {
                                    "id": "0110025",
                                    "database": "AGR",
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
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                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                                    "id": "615439",
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                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                                    "id": "615439",
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                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                {
                                    "id": "0050419",
                                    "database": "AGR",
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                            "evidence": [
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                                    "id": "610984",
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                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                {
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                },
                                {
                                    "id": "0050419",
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                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                                {
                                    "id": "615439",
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                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                            "evidence": [
                                {
                                    "id": "615439",
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                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
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                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                            "evidence": [
                                {
                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
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                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
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                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
                            "description": "A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency.",
                            "url": "http://disease-ontology.org/term/DOID:0050419",
                            "evidence": [
                                {
                                    "id": "610984",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/610984"
                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
                                }
                            ]
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 177,
                    "end_pos": 177,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        },
                        {
                            "database": "PubMed",
                            "id": "29671580",
                            "url": "https://glygen.org/publication/PubMed/29671580"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "464",
            "site_seq": "",
            "site_lbl": "N464",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->KDT).",
                    "chr_id": "4",
                    "chr_pos": "109746259",
                    "evidence": [
                        {
                            "id": "rs759927335",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs759927335"
                        },
                        {
                            "id": "rs759927335",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs759927335"
                        },
                        {
                            "id": "rs759927335",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs759927335#frequency_tab"
                        },
                        {
                            "id": "rs759927335",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs759927335"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 464,
                    "end_pos": 464,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "494",
            "site_seq": "",
            "site_lbl": "N494",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NCS->TCS).",
                    "chr_id": "4",
                    "chr_pos": "109742544",
                    "evidence": [
                        {
                            "id": "rs1723931486",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1723931486"
                        },
                        {
                            "id": "rs1723931486",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1723931486"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 494,
                    "end_pos": 494,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "536",
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            "site_lbl": "N536",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->DVT).",
                    "chr_id": "4",
                    "chr_pos": "109741039",
                    "evidence": [
                        {
                            "id": "rs1314998523",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1314998523"
                        },
                        {
                            "id": "rs1314998523",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1314998523#frequency_tab"
                        },
                        {
                            "id": "rs1314998523",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1314998523"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->KVT).",
                    "chr_id": "4",
                    "chr_pos": "109741037",
                    "evidence": [
                        {
                            "id": "rs1336453366",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1336453366"
                        },
                        {
                            "id": "rs1336453366",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1336453366#frequency_tab"
                        },
                        {
                            "id": "rs1336453366",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1336453366"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->SVT).",
                    "chr_id": "4",
                    "chr_pos": "109741038",
                    "evidence": [
                        {
                            "id": "rs1357609555",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1357609555"
                        },
                        {
                            "id": "rs1357609555",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1357609555#frequency_tab"
                        },
                        {
                            "id": "rs1357609555",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1357609555"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 536,
                    "end_pos": 536,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                }
            ]
        },
        {
            "start_pos": "70",
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            "site_lbl": "N70",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NGT->IGT).",
                    "chr_id": "4",
                    "chr_pos": "109766673",
                    "evidence": [
                        {
                            "id": "P05156",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:4159",
                            "name": "skin cancer",
                            "description": "An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells.",
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                            "evidence": [
                                {
                                    "id": "4159",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:4159"
                                }
                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NGT->TGT).",
                    "chr_id": "4",
                    "chr_pos": "109766673",
                    "evidence": [
                        {
                            "id": "rs749553820",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs749553820"
                        },
                        {
                            "id": "rs749553820",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs749553820"
                        },
                        {
                            "id": "rs749553820",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs749553820#frequency_tab"
                        },
                        {
                            "id": "rs749553820",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs749553820"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 65750.0
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            ]
        },
        {
            "start_pos": "103",
            "site_seq": "N",
            "site_lbl": "Asn103",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "evidence": [
                        {
                            "database": "PubMed",
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                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
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                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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            ]
        },
        {
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                {
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                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        },
                        {
                            "database": "PubMed",
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                            "url": "https://glygen.org/publication/PubMed/29391424"
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                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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            ]
        },
        {
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                {
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                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        },
                        {
                            "database": "PubMed",
                            "id": "29391424",
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                    ],
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            ]
        },
        {
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                        {
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                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        },
                        {
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                    ],
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            ]
        },
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                        },
                        {
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                    ],
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            ]
        },
        {
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                        {
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                    ],
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            ]
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            ]
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                    ],
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            ]
        },
        {
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                        {
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                    ],
                    "protein_name": "Complement factor I",
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            ]
        },
        {
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            "site_seq": "LISnCSK",
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                {
                    "uniprot_canonical_ac": "P05156-1",
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                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
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            "site_seq": "N",
            "site_lbl": "Asn494",
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                    "uniprot_canonical_ac": "P05156-1",
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                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
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                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "494",
            "site_seq": "LISNCSK",
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            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "end_pos": 494,
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                    "evidence": [
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                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "536",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "end_pos": 536,
                    "residue": "Asn",
                    "evidence": [
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                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
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                    "tax_name": "Homo sapiens",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "70",
            "site_seq": "N",
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                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "evidence": [
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                            "id": "29741879",
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                        },
                        {
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                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "70",
            "site_seq": "nGTAVCATNR",
            "site_lbl": "Asn70",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
                    "start_pos": 70,
                    "end_pos": 70,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                    "chemical_mass": 65750.0
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            ]
        },
        {
            "start_pos": "70",
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            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P05156-1",
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                    "end_pos": 70,
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                    "evidence": [
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                            "database": "PubMed",
                            "id": "29741879",
                            "url": "https://glygen.org/publication/PubMed/29741879"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "742",
                            "url": "https://glyconnect.expasy.org/browser/proteins/742"
                        }
                    ],
                    "protein_name": "Complement factor I",
                    "gene_name": "CFI",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 583,
                    "chemical_mass": 65750.0
                }
            ]
        },
        {
            "start_pos": "177",
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            "site_lbl": "N177",
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                {
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                    "sequence_org": "N",
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                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->HST).",
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                    "chr_pos": "109761646",
                    "evidence": [
                        {
                            "id": "P05156",
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                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
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                    ],
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                            "disease_id": "DOID:9256",
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                            "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.",
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                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
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                            ]
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
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                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NST->IST).",
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                    "chr_pos": "109761645",
                    "evidence": [
                        {
                            "id": "P05156",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P05156"
                        },
                        {
                            "id": "rs753060374",
                            "database": "dbSNP",
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                        },
                        {
                            "id": "rs753060374",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs753060374"
                        },
                        {
                            "id": "rs753060374",
                            "database": "TOPMed",
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                        },
                        {
                            "id": "rs753060374",
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                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:2531",
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                            "url": "http://disease-ontology.org/term/DOID:2531",
                            "evidence": [
                                {
                                    "id": "2531",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2531"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                                    "id": "615439",
                                    "database": "MIM",
                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
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                                    "id": "615439",
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                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
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                                {
                                    "id": "615439",
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                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                                {
                                    "id": "615439",
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                                    "url": "https://www.omim.org/entry/615439"
                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
                                }
                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                {
                                    "id": "610984",
                                    "database": "MIM",
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                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                },
                                {
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                },
                                {
                                    "id": "0050419",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0050419"
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                            ]
                        },
                        {
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                                    "id": "615439",
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                                },
                                {
                                    "id": "0110025",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
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                                    "id": "615439",
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                                },
                                {
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                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
                            "name": "age related macular degeneration 13",
                            "description": "An age related macular degeneration conferred by heterozygous mutation in the CFI gene on chromosome 4q25.",
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                                {
                                    "id": "615439",
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                                },
                                {
                                    "id": "0110025",
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                                    "url": "https://www.alliancegenome.org/disease/DOID:0110025"
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                            ]
                        },
                        {
                            "disease_id": "DOID:0110025",
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                                },
                                {
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                },
                                {
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                {
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
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                                    "id": "610984",
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                                },
                                {
                                    "id": "0050419",
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                            ]
                        },
                        {
                            "disease_id": "DOID:0050419",
                            "name": "complement factor I deficiency",
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                                },
                                {
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                                    "database": "AGR",
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                        {
                            "database": "PubMed",
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                    ],
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            ]
        },
        {
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                        {
                            "id": "rs759927335",
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                        {
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                        {
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                    ]
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            ],
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                    ],
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            ]
        },
        {
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                        {
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                    ]
                }
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                        {
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                        {
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                        {
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                        {
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                        {
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                {
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                    "sequence_org": "N",
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                        {
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                        {
                            "id": "rs752213099",
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                },
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                    ]
                },
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                            "id": "rs1157292917",
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                        {
                            "id": "rs1157292917",
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                        {
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                    ]
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                        {
                            "id": "rs2108623237",
                            "database": "ENSEMBL",
                            "url": "https://www.ensembl.org/id/rs2108623237"
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                    ]
                },
                {
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                    "sequence_org": "N",
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                    "evidence": [
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                            "database": "dbSNP",
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                        },
                        {
                            "id": "rs2108623235",
                            "database": "ENSEMBL",
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                    ]
                }
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                        {
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                        {
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                        {
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                        {
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                    ],
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                    ],
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                        {
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                        {
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                    "evidence": []
                },
                {
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                    "sequence_org": "N",
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                        {
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                            "database": "ExAC",
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                        },
                        {
                            "id": "rs752213099",
                            "database": "gnomAD",
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                    ]
                },
                {
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                            "id": "rs752213099",
                            "database": "dbSNP",
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                        {
                            "id": "rs752213099",
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                        {
                            "id": "rs752213099",
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                    ]
                },
                {
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                    "chr_pos": "186717684",
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                            "id": "rs1157292917",
                            "database": "dbSNP",
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                        {
                            "id": "rs1157292917",
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                    ],
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                        {
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                        {
                            "id": "rs773114062",
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                    "chemical_mass": 36053.0
                }
            ]
        },
        {
            "start_pos": "149",
            "site_seq": "N",
            "site_lbl": "Asn149",
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                {
                    "uniprot_canonical_ac": "P04406-1",
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                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
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                            "url": "https://glyconnect.expasy.org/browser/proteins/1941"
                        }
                    ],
                    "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase",
                    "gene_name": "GAPDH",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
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                }
            ]
        },
        {
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                {
                    "uniprot_canonical_ac": "P04406-1",
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                        {
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                        },
                        {
                            "database": "GlyConnect",
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                        }
                    ],
                    "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase",
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                    "tax_common_name": "Human",
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                }
            ]
        },
        {
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                {
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                        {
                            "database": "PubMed",
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                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
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                            "url": "https://glyconnect.expasy.org/browser/proteins/1941"
                        }
                    ],
                    "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase",
                    "gene_name": "GAPDH",
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                    "tax_common_name": "Human",
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                    "chemical_mass": 36053.0
                }
            ]
        },
        {
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            "residue": "",
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                {
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                    "sequence_org": "N",
                    "sequence_mut": "S",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAS->SAS).",
                    "chr_id": "12",
                    "chr_pos": "6537311",
                    "evidence": [
                        {
                            "id": "rs1213257920",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1213257920"
                        },
                        {
                            "id": "rs1213257920",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1213257920#frequency_tab"
                        },
                        {
                            "id": "rs1213257920",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1213257920"
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                    ]
                }
            ],
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                {
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                        {
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                        },
                        {
                            "database": "GlyConnect",
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                            "url": "https://glyconnect.expasy.org/browser/proteins/1941"
                        }
                    ],
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            ]
        },
        {
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                {
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                    "chr_pos": "6537773",
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                        {
                            "id": "rs1176982645",
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                        },
                        {
                            "id": "rs1176982645",
                            "database": "ENSEMBL",
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                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
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                    "evidence": [
                        {
                            "id": "P04406",
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                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P04406"
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                    ],
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                        {
                            "disease_id": "DOID:1319",
                            "name": "brain cancer",
                            "description": "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.",
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                            "evidence": [
                                {
                                    "id": "1319",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:1319"
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                            ]
                        }
                    ]
                }
            ],
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                        },
                        {
                            "database": "GlyConnect",
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                            "url": "https://glyconnect.expasy.org/browser/proteins/1941"
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                    ],
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            ]
        },
        {
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                {
                    "uniprot_canonical_ac": "P14651-1",
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                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "1942",
                            "url": "https://glyconnect.expasy.org/browser/proteins/1942"
                        }
                    ],
                    "protein_name": "Homeobox protein Hox-B3",
                    "gene_name": "HOXB3",
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                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 431,
                    "chemical_mass": 44340.0
                }
            ]
        },
        {
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                {
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                        {
                            "database": "PubMed",
                            "id": "29391424",
                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
                            "id": "1942",
                            "url": "https://glyconnect.expasy.org/browser/proteins/1942"
                        }
                    ],
                    "protein_name": "Homeobox protein Hox-B3",
                    "gene_name": "HOXB3",
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            ]
        },
        {
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                            "url": "https://glygen.org/publication/PubMed/29391424"
                        },
                        {
                            "database": "GlyConnect",
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                        }
                    ],
                    "protein_name": "Homeobox protein Hox-B3",
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            ]
        },
        {
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                        {
                            "id": "P14651",
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                        }
                    ],
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                            "description": "An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells.",
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                            "evidence": [
                                {
                                    "id": "4159",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:4159"
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                            ]
                        }
                    ]
                }
            ],
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                        },
                        {
                            "database": "GlyConnect",
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                    ],
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            ]
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                    ],
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            ]
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            ]
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                    ],
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            ]
        },
        {
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                        {
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                    ],
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            ]
        },
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                {
                    "uniprot_canonical_ac": "Q99650-1",
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                        {
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                        },
                        {
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                    ],
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                }
            ]
        },
        {
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            ]
        },
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                    ],
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                        {
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                            "evidence": [
                                {
                                    "id": "2531",
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                                    "url": "https://www.alliancegenome.org/disease/DOID:2531"
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                    ]
                }
            ],
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                        {
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                    ],
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            ]
        },
        {
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                        {
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                    ],
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                }
            ]
        },
        {
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                        },
                        {
                            "database": "GlyConnect",
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                        }
                    ],
                    "protein_name": "Protocadherin-9",
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                    "chemical_mass": 136064.0
                }
            ]
        },
        {
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                {
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                            "database": "PubMed",
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                        },
                        {
                            "database": "GlyConnect",
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                    ],
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            ]
        },
        {
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                            "id": "Q9HC56",
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                    ],
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                                {
                                    "id": "3571",
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                            ]
                        }
                    ]
                },
                {
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                    ],
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                                {
                                    "id": "9256",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:9256"
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                            ]
                        }
                    ]
                }
            ],
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                    ],
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            ]
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                    ],
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            ]
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            ]
        },
        {
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                        {
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                        {
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                                {
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                                {
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                    "gene_name": "IGHG3",
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                    "tax_common_name": "Human",
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                    "chemical_mass": 49093.0
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                    ],
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            ]
        },
        {
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                    ],
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                        {
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                        {
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                        {
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