{
    "glytoucan_ac": "G00227RN",
    "species": [
        {
            "taxid": 10029,
            "name": "Cricetulus griseus",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G45209NR",
                    "url": "https://www.glygen.org/glycan/G45209NR"
                },
                {
                    "database": "Subsumption",
                    "id": "G91413ZX",
                    "url": "https://www.glygen.org/glycan/G91413ZX"
                }
            ],
            "common_name": "Chinese hamster",
            "glygen_name": "Hamster",
            "reference_species": "Cricetulus griseus [10029]"
        },
        {
            "taxid": 9606,
            "name": "Homo sapiens",
            "annotation_category": "both",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G45209NR",
                    "url": "https://www.glygen.org/glycan/G45209NR"
                },
                {
                    "database": "Subsumption",
                    "id": "G91413ZX",
                    "url": "https://www.glygen.org/glycan/G91413ZX"
                },
                {
                    "database": "GlyConnect",
                    "id": "1772",
                    "url": "https://glyconnect.expasy.org/browser/structures/1772"
                },
                {
                    "database": "PubMed",
                    "id": "8942648",
                    "url": "https://glygen.org/publication/PubMed/8942648"
                },
                {
                    "database": "UniCarbKB",
                    "id": "GLY_000341",
                    "url": "http://data.glygen.org/GLY_000341"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        },
        {
            "taxid": 10090,
            "name": "Mus musculus",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G45209NR",
                    "url": "https://www.glygen.org/glycan/G45209NR"
                },
                {
                    "database": "Subsumption",
                    "id": "G91413ZX",
                    "url": "https://www.glygen.org/glycan/G91413ZX"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        },
        {
            "taxid": 10116,
            "name": "Rattus norvegicus",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G91413ZX",
                    "url": "https://www.glygen.org/glycan/G91413ZX"
                }
            ],
            "common_name": "Rat",
            "glygen_name": "Rat",
            "reference_species": "Rattus norvegicus [10116]"
        },
        {
            "taxid": 10114,
            "name": "Rattus",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G91413ZX",
                    "url": "https://www.glygen.org/glycan/G91413ZX"
                }
            ],
            "common_name": "Rattus",
            "glygen_name": "Rattus",
            "reference_species": "Rattus [10114]"
        }
    ],
    "mass": 3025.07,
    "classification": [
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Complex",
                "url": ""
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Core-fucosylated"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Triantennary"
            }
        }
    ],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 1,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 6,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 5,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 3,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 0,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "motifs": [
        {
            "id": "GGM.000001",
            "name": "Type 2 LN",
            "synonym": "N-acetyllactosamine",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 2"
        },
        {
            "id": "GGM.000034",
            "name": "3-Sialyl-LN (type 2)",
            "synonym": "",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 2"
        }
    ],
    "enzyme": [],
    "biomarkers": [],
    "binding_proteins": [],
    "sites": [
        {
            "start_pos": "197",
            "site_seq": "N",
            "site_lbl": "Asn197",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P40225-1",
                    "start_pos": 197,
                    "end_pos": 197,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8942648",
                            "url": "https://glygen.org/publication/PubMed/8942648"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Thrombopoietin",
                    "gene_name": "THPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 353,
                    "chemical_mass": 37823.0
                }
            ]
        },
        {
            "start_pos": "197",
            "site_seq": "N",
            "site_lbl": "Asn197",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P40225-1",
                    "start_pos": 197,
                    "end_pos": 197,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8942648",
                            "url": "https://glygen.org/publication/PubMed/8942648"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Thrombopoietin",
                    "gene_name": "THPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 353,
                    "chemical_mass": 37823.0
                }
            ]
        },
        {
            "start_pos": "197",
            "site_seq": "N",
            "site_lbl": "Asn197",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P40225-1",
                    "start_pos": 197,
                    "end_pos": 197,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8942648",
                            "url": "https://glygen.org/publication/PubMed/8942648"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Thrombopoietin",
                    "gene_name": "THPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 353,
                    "chemical_mass": 37823.0
                }
            ]
        },
        {
            "start_pos": "197",
            "site_seq": "",
            "site_lbl": "N197",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->DRT).",
                    "chr_id": "3",
                    "chr_pos": "184372986",
                    "evidence": [
                        {
                            "id": "rs773045931",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773045931"
                        },
                        {
                            "id": "rs773045931",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773045931"
                        },
                        {
                            "id": "rs773045931",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs773045931#frequency_tab"
                        },
                        {
                            "id": "rs773045931",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773045931"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->IRT).",
                    "chr_id": "3",
                    "chr_pos": "184372869",
                    "evidence": [
                        {
                            "id": "rs1314113189",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1314113189"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1314113189#frequency_tab"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1314113189"
                        },
                        {
                            "id": "rs1284651132",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1284651132"
                        },
                        {
                            "id": "rs1284651132",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1284651132#frequency_tab"
                        },
                        {
                            "id": "rs1284651132",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1284651132"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->KRT).",
                    "chr_id": "3",
                    "chr_pos": "184372984",
                    "evidence": [
                        {
                            "id": "rs1331659576",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1331659576"
                        },
                        {
                            "id": "rs1331659576",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1331659576#frequency_tab"
                        },
                        {
                            "id": "rs1331659576",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1331659576"
                        },
                        {
                            "id": "rs1331659576",
                            "database": "COSMIC",
                            "url": "https://www.ensembl.org/homo_sapiens/Variation/Explore?v=rs1331659576"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->TRT).",
                    "chr_id": "3",
                    "chr_pos": "184372869",
                    "evidence": [
                        {
                            "id": "rs1314113189",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1314113189"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1314113189#frequency_tab"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1314113189"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P40225-1",
                    "start_pos": 197,
                    "end_pos": 197,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8942648",
                            "url": "https://glygen.org/publication/PubMed/8942648"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Thrombopoietin",
                    "gene_name": "THPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 353,
                    "chemical_mass": 37823.0
                }
            ]
        },
        {
            "start_pos": "197",
            "site_seq": "N",
            "site_lbl": "Asn197",
            "residue": "Asn",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P40225-1",
                    "start_pos": 197,
                    "end_pos": 197,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8942648",
                            "url": "https://glygen.org/publication/PubMed/8942648"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Thrombopoietin",
                    "gene_name": "THPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 353,
                    "chemical_mass": 37823.0
                }
            ]
        },
        {
            "start_pos": "197",
            "site_seq": "",
            "site_lbl": "N197",
            "residue": "",
            "snv": [
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->DRT).",
                    "chr_id": "3",
                    "chr_pos": "184372986",
                    "evidence": [
                        {
                            "id": "rs773045931",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773045931"
                        },
                        {
                            "id": "rs773045931",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773045931"
                        },
                        {
                            "id": "rs773045931",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs773045931#frequency_tab"
                        },
                        {
                            "id": "rs773045931",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773045931"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->IRT).",
                    "chr_id": "3",
                    "chr_pos": "184372869",
                    "evidence": [
                        {
                            "id": "rs1314113189",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1314113189"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1314113189#frequency_tab"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1314113189"
                        },
                        {
                            "id": "rs1284651132",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1284651132"
                        },
                        {
                            "id": "rs1284651132",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1284651132#frequency_tab"
                        },
                        {
                            "id": "rs1284651132",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1284651132"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Somatic mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->KRT).",
                    "chr_id": "3",
                    "chr_pos": "184372984",
                    "evidence": [
                        {
                            "id": "rs1331659576",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1331659576"
                        },
                        {
                            "id": "rs1331659576",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1331659576#frequency_tab"
                        },
                        {
                            "id": "rs1331659576",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1331659576"
                        },
                        {
                            "id": "rs1331659576",
                            "database": "COSMIC",
                            "url": "https://www.ensembl.org/homo_sapiens/Variation/Explore?v=rs1331659576"
                        }
                    ]
                },
                {
                    "weight": 100,
                    "sequence_org": "N",
                    "sequence_mut": "T",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NRT->TRT).",
                    "chr_id": "3",
                    "chr_pos": "184372869",
                    "evidence": [
                        {
                            "id": "rs1314113189",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1314113189"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1314113189#frequency_tab"
                        },
                        {
                            "id": "rs1314113189",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs1314113189"
                        }
                    ]
                }
            ],
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "P40225-1",
                    "start_pos": 197,
                    "end_pos": 197,
                    "residue": "asn",
                    "evidence": [
                        {
                            "database": "PubMed",
                            "id": "8942648",
                            "url": "https://glygen.org/publication/PubMed/8942648"
                        },
                        {
                            "database": "UniCarbKB",
                            "id": "GLY_000040",
                            "url": "http://data.glygen.org/GLY_000040"
                        }
                    ],
                    "protein_name": "Thrombopoietin",
                    "gene_name": "THPO",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "length": 353,
                    "chemical_mass": 37823.0
                }
            ]
        }
    ],
    "record_id": "G00227RN"
}