{
    "glytoucan_ac": "G06014UR",
    "species": [
        {
            "taxid": 9031,
            "name": "Gallus gallus",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G04791QM",
                    "url": "https://www.glygen.org/glycan/G04791QM"
                },
                {
                    "database": "Subsumption",
                    "id": "G24585JV",
                    "url": "https://www.glygen.org/glycan/G24585JV"
                }
            ],
            "common_name": "Chicken",
            "glygen_name": "Chicken",
            "reference_species": "Gallus gallus [9031]"
        },
        {
            "taxid": 9606,
            "name": "Homo sapiens",
            "annotation_category": "both",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G04791QM",
                    "url": "https://www.glygen.org/glycan/G04791QM"
                },
                {
                    "database": "Subsumption",
                    "id": "G24585JV",
                    "url": "https://www.glygen.org/glycan/G24585JV"
                },
                {
                    "database": "Subsumption",
                    "id": "G04604BY",
                    "url": "https://www.glygen.org/glycan/G04604BY"
                },
                {
                    "database": "GlyGen",
                    "id": "GLY_000737",
                    "url": "https://data.glygen.org/GLY_000737"
                },
                {
                    "database": "PubMed",
                    "id": "19441788",
                    "url": "https://glygen.org/publication/PubMed/19441788"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        },
        {
            "taxid": 7227,
            "name": "Drosophila melanogaster",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G04604BY",
                    "url": "https://www.glygen.org/glycan/G04604BY"
                }
            ],
            "common_name": "Fruit fly",
            "glygen_name": "Fruit fly",
            "reference_species": "Drosophila melanogaster [7227]"
        }
    ],
    "mass": 1769.63,
    "classification": [
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Biantennary"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Complex",
                "url": ""
            }
        }
    ],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 0,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 4,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 4,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 1,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 0,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "motifs": [
        {
            "id": "GGM.000001",
            "name": "Type 2 LN",
            "synonym": "N-acetyllactosamine",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 2",
            "weight": 2804.9
        },
        {
            "id": "GGM.000005",
            "name": "Type 1 LN",
            "synonym": "",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 1",
            "weight": 1436.7
        },
        {
            "id": "GGM.000034",
            "name": "3-Sialyl-LN (type 2)",
            "synonym": "",
            "keywords": "LacNAc; N-acetyllactosamine; N-acetyllactosamine type 2",
            "weight": 912.9
        }
    ],
    "enzyme": [],
    "biomarkers": [
        {
            "biomarker_id": "AN6738-1",
            "biomarker_canonical_id": "AN6738",
            "best_biomarker_role": [
                {
                    "role": "diagnostic"
                }
            ],
            "biomarker_component": [
                {
                    "biomarker": "decreased N-glycan level",
                    "assessed_biomarker_entity_id": "G06014UR",
                    "assessed_entity_type": "glycan",
                    "assessed_biomarker_entity": {
                        "recommended_name": "Monosialylated monogalactosylated biantennary N-glycan",
                        "synonyms": []
                    },
                    "specimen": [
                        {
                            "name": "blood",
                            "namespace": "UBERON",
                            "id": "0000178",
                            "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                            "loinc_code": ""
                        }
                    ],
                    "evidence_source": [
                        {
                            "id": "AN6738-1",
                            "database": "BiomarkerKB",
                            "url": "https://biomarkerkb.org/biomarker/AN6738-1"
                        },
                        {
                            "id": "19441788",
                            "database": "PubMed",
                            "url": "https://glygen.org/publication/PubMed/19441788",
                            "tags": [
                                "assessed_biomarker_entity",
                                " biomarker",
                                " specimen"
                            ],
                            "evidence_list": [
                                {
                                    "evidence": "The changes in the relative intensities of three of the known glycan structures predicted esophageal adenocarcinoma with 94% sensitivity and better than 60% specificity as determined by receiver operating characteristic (ROC) analysis. We have demonstrated that comparative glycomic profiling of EAC reveals a subset of glycans that can be selected as candidate biomarkers. These markers can differentiate disease-free from HGD, disease-free from EAC, and HGD from EAC."
                                }
                            ]
                        }
                    ]
                }
            ],
            "condition": {
                "id": "DOID:5041",
                "recommended_name": {
                    "id": "DOID:5041",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5041",
                    "name": "esophageal cancer",
                    "description": "A gastrointestinal system cancer that is located_in the esophagus."
                }
            },
            "weight": 0.3
        }
    ],
    "binding_proteins": [],
    "sites": [],
    "record_id": "G06014UR"
}