{
    "glytoucan_ac": "G03692CL",
    "species": [
        {
            "taxid": 9606,
            "name": "Homo sapiens",
            "annotation_category": "direct",
            "evidence": [
                {
                    "database": "GlyGen",
                    "id": "GLY_000737",
                    "url": "https://data.glygen.org/GLY_000737"
                },
                {
                    "database": "PubMed",
                    "id": "18487288",
                    "url": "https://glygen.org/publication/PubMed/18487288"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        },
        {
            "taxid": 10090,
            "name": "Mus musculus",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G76519VT",
                    "url": "https://www.glygen.org/glycan/G76519VT"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        },
        {
            "taxid": 7955,
            "name": "Danio rerio",
            "annotation_category": "subsumption",
            "evidence": [
                {
                    "database": "Subsumption",
                    "id": "G24943NZ",
                    "url": "https://www.glygen.org/glycan/G24943NZ"
                }
            ],
            "common_name": "Zebrafish",
            "glygen_name": "Zebrafish",
            "reference_species": "Danio rerio [7955]"
        }
    ],
    "mass": 2717.98,
    "classification": [
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Arm-fucosylated"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Biantennary"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Bisected"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Complex",
                "url": ""
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Core-fucosylated"
            }
        },
        {
            "type": {
                "name": "N-linked",
                "url": ""
            },
            "subtype": {
                "name": "Triantennary"
            }
        }
    ],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 2,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 5,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 5,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 2,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 0,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "motifs": [],
    "enzyme": [],
    "biomarkers": [
        {
            "biomarker_id": "BB1517-1",
            "biomarker_canonical_id": "BB1517",
            "best_biomarker_role": [
                {
                    "role": "diagnostic"
                }
            ],
            "biomarker_component": [
                {
                    "biomarker": "increased N-glycan level",
                    "assessed_biomarker_entity_id": "G03692CL",
                    "assessed_entity_type": "glycan",
                    "assessed_biomarker_entity": {
                        "recommended_name": "Disialylated Lewis fucosylated triantennary core fucosylated N-glycan",
                        "synonyms": []
                    },
                    "specimen": [
                        {
                            "name": "blood",
                            "namespace": "UBERON",
                            "id": "0000178",
                            "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                            "loinc_code": ""
                        }
                    ],
                    "evidence_source": [
                        {
                            "id": "BB1517-1",
                            "database": "BiomarkerKB",
                            "url": "https://biomarkerkb.org/biomarker/BB1517-1"
                        },
                        {
                            "id": "18487288",
                            "database": "PubMed",
                            "url": "https://glygen.org/publication/PubMed/18487288",
                            "tags": [
                                "assessed_biomarker_entity",
                                " biomarker",
                                " specimen"
                            ],
                            "evidence_list": [
                                {
                                    "evidence": "Two statistical procedures implicated several sialylated and fucosylated N-glycan structures as highly probable biomarkers. Quantitative changes according to a cancer stage resulted when we categorized the glycans according to molecular size, number of oligomer branches, and abundance of sugar residues. Increases in sialylation and fucosylation of glycan structures appeared to be indicative of cancer progression. Different statistical evaluations confirmed independently that changes in the relative intensities of 8 N-glycans are characteristic of breast cancer (P < 0.001), whereas other glycan structures might contribute additionally to distinctions in the statistically recognizable patterns (different stages)."
                                }
                            ]
                        }
                    ]
                }
            ],
            "condition": {
                "id": "DOID:1612",
                "recommended_name": {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "breast cancer",
                    "description": "An organ system cancer that originates in the mammary gland."
                }
            },
            "weight": 0.3
        }
    ],
    "binding_proteins": [],
    "sites": [],
    "record_id": "G03692CL"
}