{
    "glytoucan_ac": "G02852RP",
    "species": [
        {
            "taxid": 9606,
            "name": "Homo sapiens",
            "annotation_category": "direct",
            "evidence": [
                {
                    "database": "DOI",
                    "id": "10.1101/2023.09.13.557529",
                    "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                },
                {
                    "database": "GlyGen",
                    "id": "GLY_000888",
                    "url": "https://data.glygen.org/GLY_000888"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        },
        {
            "taxid": 10090,
            "name": "Mus musculus",
            "annotation_category": "direct",
            "evidence": [
                {
                    "database": "DOI",
                    "id": "10.1101/2023.09.13.557529",
                    "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                },
                {
                    "database": "GlyGen",
                    "id": "GLY_000889",
                    "url": "https://data.glygen.org/GLY_000889"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "mass": 2213.75,
    "classification": [
        {
            "type": {
                "name": "Other",
                "url": ""
            },
            "subtype": {
                "name": "Other",
                "url": ""
            }
        }
    ],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 0,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 6,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 3,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 0,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 2,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 0,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "motifs": [],
    "enzyme": [],
    "biomarkers": [],
    "binding_proteins": [],
    "sites": [
        {
            "start_pos": "317",
            "end_pos": "44",
            "site_lbl": "Asn317",
            "weight": 0.0,
            "uniprot_canonical_ac": "O15111-1",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "O15111-1",
                    "start_pos": 317,
                    "end_pos": 317,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "Data Submission",
                            "id": "GLY_000888",
                            "url": "http://data.glygen.org/GLY_000888"
                        }
                    ],
                    "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha",
                    "gene_name": "CHUK",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "weight": 65.5,
                    "length": 745,
                    "chemical_mass": 84640.0
                }
            ]
        },
        {
            "start_pos": "2341",
            "end_pos": "953",
            "site_lbl": "Asn2341",
            "weight": 0.0,
            "snv": [
                {
                    "sequence_org": "N",
                    "sequence_mut": "D",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->DSS).",
                    "chr_id": "5",
                    "chr_pos": "140535532",
                    "evidence": [
                        {
                            "id": "rs773196871",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773196871"
                        },
                        {
                            "id": "rs773196871",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773196871"
                        },
                        {
                            "id": "rs773196871",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs773196871#frequency_tab"
                        },
                        {
                            "id": "rs773196871",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773196871"
                        }
                    ]
                },
                {
                    "sequence_org": "N",
                    "sequence_mut": "I",
                    "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NSS->ISS).",
                    "chr_id": "5",
                    "chr_pos": "140535533",
                    "evidence": [
                        {
                            "id": "Q8IWZ3",
                            "database": "BioMuta",
                            "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/Q8IWZ3"
                        }
                    ],
                    "disease": [
                        {
                            "disease_id": "DOID:2394",
                            "name": "ovarian cancer",
                            "description": "A female reproductive organ cancer that is located_in the ovary.",
                            "url": "http://disease-ontology.org/term/DOID:2394",
                            "evidence": [
                                {
                                    "id": "2394",
                                    "database": "AGR",
                                    "url": "https://www.alliancegenome.org/disease/DOID:2394"
                                }
                            ]
                        }
                    ]
                },
                {
                    "sequence_org": "N",
                    "sequence_mut": "K",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->KSS).",
                    "chr_id": "5",
                    "chr_pos": "140535534",
                    "evidence": [
                        {
                            "id": "rs1754030037",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1754030037"
                        },
                        {
                            "id": "rs1754030037",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs1754030037#frequency_tab"
                        }
                    ]
                },
                {
                    "sequence_org": "N",
                    "sequence_mut": "Y",
                    "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NSS->YSS).",
                    "chr_id": "5",
                    "chr_pos": "140535532",
                    "evidence": [
                        {
                            "id": "rs773196871",
                            "database": "dbSNP",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773196871"
                        },
                        {
                            "id": "rs773196871",
                            "database": "ExAC",
                            "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs773196871"
                        },
                        {
                            "id": "rs773196871",
                            "database": "TOPMed",
                            "url": "https://www.ncbi.nlm.nih.gov/snp/rs773196871#frequency_tab"
                        },
                        {
                            "id": "rs773196871",
                            "database": "gnomAD",
                            "url": "http://gnomad.broadinstitute.org/awesome?query=rs773196871"
                        }
                    ]
                }
            ],
            "uniprot_canonical_ac": "Q8IWZ3-1",
            "glycoprotein": [
                {
                    "uniprot_canonical_ac": "Q8IWZ3-1",
                    "start_pos": 2341,
                    "end_pos": 2341,
                    "residue": "Asn",
                    "evidence": [
                        {
                            "database": "DOI",
                            "id": "10.1101/2023.09.13.557529",
                            "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529"
                        },
                        {
                            "database": "Data Submission",
                            "id": "GLY_000888",
                            "url": "http://data.glygen.org/GLY_000888"
                        }
                    ],
                    "protein_name": "Ankyrin repeat and KH domain-containing protein 1",
                    "gene_name": "ANKHD1",
                    "tax_id": 9606,
                    "tax_name": "Homo sapiens",
                    "tax_common_name": "Human",
                    "weight": 17.0,
                    "length": 2542,
                    "chemical_mass": 269458.0
                }
            ]
        }
    ],
    "record_id": "G02852RP"
}