{
    "disease_id": "DOID:10941",
    "recommended_name": {
        "id": "DOID:10941",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:10941",
        "name": "intracranial aneurysm",
        "description": ""
    },
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            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:10941",
            "name": "brain aneurysm",
            "description": ""
        }
    ],
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        {
            "id": "DOID:0060228",
            "label": "intracranial berry aneurysm",
            "link_status": false,
            "children": [
                {
                    "id": "DOID:0080975",
                    "label": "intracranial berry aneurysm 12",
                    "link_status": true,
                    "children": []
                }
            ]
        }
    ],
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    ],
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    ],
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            "id": "DOID:10941",
            "database": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:10941",
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        }
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            ],
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                {
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                }
            ]
        },
        {
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                {
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                }
            ],
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                {
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                },
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                {
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                {
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            ],
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                {
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                }
            ]
        },
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            ],
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                }
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                }
            ]
        },
        {
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                }
            ],
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                {
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                },
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                {
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                },
                {
                    "name": "cathepsin B, isoform C",
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                }
            ],
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                {
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                {
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                {
                    "name": "anon-EST:ParkEST132",
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                }
            ],
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                    "id": "10941",
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                }
            ]
        },
        {
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                }
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                {
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                }
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                }
            ],
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                {
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                {
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                {
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            ],
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                },
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                }
            ]
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                }
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                {
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                },
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                },
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                {
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                }
            ],
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                    "id": "10941",
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                }
            ]
        },
        {
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                }
            ],
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                {
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                {
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                }
            ],
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                {
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                },
                {
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                },
                {
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                },
                {
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                },
                {
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                },
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                },
                {
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                },
                {
                    "name": "Dmel\\CG11459",
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                },
                {
                    "name": "Dmel\\CG11459",
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                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG11459",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
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                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9VZN4-1",
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            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Drosophila melanogaster",
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                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
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                {
                    "name": "Dendritic arbor reduction protein 1",
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                    "type": "recommended"
                },
                {
                    "name": "CG12029-PB",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "dar1-PB",
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                    "type": "synonym"
                },
                {
                    "name": "dendritic arbor reduction 1",
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                },
                {
                    "name": "lethal (3) 63Ed",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "dar1",
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                },
                {
                    "name": "CG12029",
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                    "type": "synonym"
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                    "name": "TIMP-1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tissue inhibitor of metalloproteinases 1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 1 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metallopeptidase 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metalloproteinase 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metalloproteinases 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "Timp1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "TIMP-1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Timp-1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Timp1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Timp",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P30121-1",
            "uniprot_ac": "P30121",
            "uniprot_id": "TIMP2_RAT",
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            "glycoprotein": "no",
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                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
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                {
                    "name": "Metalloproteinase inhibitor 2",
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                    "type": "recommended"
                },
                {
                    "name": "TIMP-2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TIMP-2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tissue inhibitor of metalloproteinases 2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 2 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metalloproteinase 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metalloproteinases 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Cep295nl",
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                },
                {
                    "name": "Timp2",
                    "resource": "UniProtKB",
                    "type": "recommended"
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                {
                    "name": "Timp-2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Timp2",
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                    "type": "synonym"
                },
                {
                    "name": "Timp2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
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                }
            ]
        },
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                {
                    "name": "Cystatin-C",
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                {
                    "name": "Cystatin C (cysteine proteinase inhibitor)",
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                {
                    "name": "Cystatin-3",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "cystatin-3",
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                },
                {
                    "name": "cystatin-C precursor",
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                    "type": "synonym"
                }
            ],
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                {
                    "name": "Cst3",
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                },
                {
                    "name": "CYSC",
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                    "type": "synonym"
                },
                {
                    "name": "Cst3",
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                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
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            ]
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                }
            ],
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                    "name": "CCN family member 1",
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                {
                    "name": "CCN family member 1 precursor",
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                },
                {
                    "name": "CCN family member 1",
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                {
                    "name": "Cellular communication network factor 1",
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                    "type": "synonym"
                },
                {
                    "name": "Cysteine-rich angiogenic inducer 61",
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                {
                    "name": "IBP-10",
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                    "type": "synonym"
                },
                {
                    "name": "IBP-10",
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                    "type": "synonym"
                },
                {
                    "name": "IGF-binding protein 10",
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                    "type": "synonym"
                },
                {
                    "name": "IGF-binding protein 10",
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                    "type": "synonym"
                },
                {
                    "name": "IGFBP-10",
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                    "type": "synonym"
                },
                {
                    "name": "IGFBP-10",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Insulin-like growth factor-binding protein 10",
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                    "type": "synonym"
                },
                {
                    "name": "Protein CYR61",
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                    "type": "synonym"
                },
                {
                    "name": "cysteine rich protein 61",
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                {
                    "name": "cysteine-rich, angiogenic inducer, 61",
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                    "type": "synonym"
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                {
                    "name": "insulin-like growth factor-binding protein 10",
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                    "type": "synonym"
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                    "name": "protein CYR61",
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                    "type": "synonym"
                }
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                    "name": "Ccn1",
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                },
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                    "name": "Cyr61",
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                },
                {
                    "name": "Cyr61",
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                    "type": "synonym"
                },
                {
                    "name": "Igfbp10",
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                }
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                    "id": "10941",
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            ]
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            ],
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                    "name": "Cathepsin S",
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                {
                    "name": "3.4.22.27",
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                {
                    "name": "cathepsin S preproprotein",
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                }
            ],
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                    "name": "Ctss",
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                    "name": "Ctss",
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                {
                    "id": "10941",
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                }
            ]
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                    "taxid": 10116,
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                    "reference_species": "Rattus norvegicus [10116]"
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            ],
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                {
                    "name": "Cathepsin K",
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                {
                    "name": "3.4.22.38",
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                },
                {
                    "name": "cathepsin K precursor",
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                    "type": "synonym"
                }
            ],
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                {
                    "name": "Ctsk",
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                },
                {
                    "name": "Ctsk",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
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                }
            ]
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        {
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                    "name": "Rattus norvegicus",
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                    "common_name": "Rat",
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                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
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                {
                    "name": "Tumor necrosis factor",
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                {
                    "name": "Cachectin",
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                    "type": "synonym"
                },
                {
                    "name": "N-terminal fragment",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "NTF",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "TNF-alpha",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "TNF-a",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tumor necrosis factor ligand superfamily member 2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "cachectin",
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                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor (TNF superfamily, member 2)",
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                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor ligand superfamily member 2",
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                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor",
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                    "type": "synonym"
                }
            ],
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                    "name": "Tnf",
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                {
                    "name": "RATTNF",
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                    "type": "synonym"
                },
                {
                    "name": "TNF-alpha",
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                    "type": "synonym"
                },
                {
                    "name": "Tnfa",
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                },
                {
                    "name": "Tnfa",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tnfsf2",
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                    "type": "synonym"
                },
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                    "name": "Tnf",
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                    "type": "synonym"
                }
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                {
                    "id": "10941",
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                }
            ],
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                {
                    "name": "Collagen alpha-2(I) chain",
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                {
                    "name": "Alpha-2 type I collagen",
                    "resource": "UniProtKB",
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                },
                {
                    "name": "alpha-2 type I collagen",
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                    "type": "synonym"
                },
                {
                    "name": "collagen alpha-2(I) chain precursor",
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                    "type": "synonym"
                },
                {
                    "name": "collagen alpha-2(I) chain",
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                    "type": "synonym"
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                {
                    "name": "collagen, type I, alpha 2",
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                    "type": "synonym"
                },
                {
                    "name": "procollagen, type I, alpha 2",
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                    "type": "synonym"
                }
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                {
                    "name": "Col1a2",
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                },
                {
                    "name": "Col1a2",
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            ],
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                {
                    "id": "10941",
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            ]
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            ],
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                    "name": "Collagen type XXII alpha 1 chain",
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                {
                    "name": "Col22a1",
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            ],
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                {
                    "id": "10941",
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                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
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            ]
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        {
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                }
            ],
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                    "name": "Endoglin",
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                {
                    "name": "Eng",
                    "resource": "UniProtKB",
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            ],
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                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
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                    "reference_species": "Rattus norvegicus [10116]"
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                    "name": "Interleukin-6",
                    "resource": "UniProtKB",
                    "type": "recommended"
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                {
                    "name": "IL-6",
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                    "type": "synonym"
                },
                {
                    "name": "IL-6",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Interleukin 6 (interferon, beta 2)",
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                    "type": "synonym"
                },
                {
                    "name": "interleukin-6 precursor",
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                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Il6",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "ILg6",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Ifnb2",
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                    "type": "synonym"
                },
                {
                    "name": "Il-6",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Il6",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
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                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
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        {
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                    "name": "Rattus norvegicus",
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                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
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                {
                    "name": "Histone-lysine N-methyltransferase 2D",
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                    "type": "recommended"
                },
                {
                    "name": "2.1.1.364",
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                    "type": "synonym"
                },
                {
                    "name": "ALL1-related protein",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Myeloid/lymphoid or mixed-lineage leukemia protein 2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "histone-lysine N-methyltransferase 2D isoform X11",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kmt2d",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "Kmt2d",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Mll2",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "F1MAD3-1",
            "uniprot_ac": "F1MAD3",
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            "glycoprotein": "yes",
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                {
                    "name": "Rattus norvegicus",
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                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Polycystin-1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "polycystic kidney disease 1 homolog",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "polycystin-1 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
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                {
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                    "name": "polycystic kidney disease 2 (autosomal dominant)",
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                {
                    "name": "polycystic kidney disease 2 homolog",
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                {
                    "name": "polycystin-2",
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                },
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                    "name": "RGD1559992",
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                    "id": "10941",
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                    "id": "10941",
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                {
                    "name": "Chondroitin sulfate proteoglycan 2",
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                {
                    "name": "Chondroitin sulfate proteoglycan core protein 2",
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                {
                    "name": "large fibroblast proteoglycan",
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                },
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                }
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                    "id": "10941",
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                {
                    "name": "B-cell CLL/lymphoma 2",
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                {
                    "name": "B-cell leukemia/lymphoma 2",
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                    "id": "10941",
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                    "id": "10941",
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                    "name": "Membrane-type-1 matrix metalloproteinase",
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                    "id": "10941",
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                {
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                {
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                    "id": "10941",
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                    "name": "Cytochrome P450 2E1",
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                {
                    "name": "1.14.14.1",
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                {
                    "name": "4-nitrophenol 2-hydroxylase",
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                },
                {
                    "name": "4-nitrophenol 2-hydroxylase",
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                    "name": "CYPIIE1",
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                },
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                    "name": "CYPIIE1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Cytochrome P450-J",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Cytochrome P450RLM6",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "P450-J",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "P450RLM6",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 2E1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 subfamily 2e1 (ethanol-inducible)",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450, subfamily 2E, polypeptide 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450-J",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450RLM6",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "Cyp2e1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "Cyp2e-1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Cyp2e1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Cyp2e",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Cyp2e",
                    "resource": "UniProtKB",
                    "type": "synonym"
                }
            ],
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                    "id": "10941",
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            ]
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                }
            ],
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                {
                    "name": "Early growth response protein 3",
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                    "type": "recommended"
                },
                {
                    "name": "EGR-3",
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                },
                {
                    "name": "early growth response protein 3",
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                    "type": "synonym"
                }
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                {
                    "name": "Egr3",
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                },
                {
                    "name": "EGR-3",
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                },
                {
                    "name": "Egr-3",
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                    "name": "Egr3",
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                    "id": "10941",
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                }
            ]
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            ],
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                    "name": "Endothelin receptor type B",
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                    "name": "ET-BR",
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                },
                {
                    "name": "ET-BR",
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                },
                {
                    "name": "ET-B",
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                },
                {
                    "name": "ET-B",
                    "resource": "UniProtKB",
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                },
                {
                    "name": "Endothelin receptor non-selective type",
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                    "type": "synonym"
                },
                {
                    "name": "endothelin B receptor",
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                },
                {
                    "name": "endothelin receptor non-selective type",
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                    "type": "synonym"
                },
                {
                    "name": "endothelin receptor type B precursor",
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                }
            ],
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                {
                    "name": "Ednrb",
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                },
                {
                    "name": "Ednra",
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                },
                {
                    "name": "Ednrb",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Etb",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
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            ]
        },
        {
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                }
            ],
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                {
                    "name": "Growth arrest and DNA damage-inducible protein GADD45 alpha",
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                {
                    "name": "DDIT-1",
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                },
                {
                    "name": "DNA damage-inducible transcript 1 protein",
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                    "type": "synonym"
                }
            ],
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                {
                    "name": "Gadd45a",
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                {
                    "name": "Ddit1",
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                },
                {
                    "name": "Gadd45",
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                }
            ],
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                {
                    "id": "10941",
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            ]
        },
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            ],
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                    "name": "Cytochrome P450 2A2",
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                    "name": "CYPIIA2",
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                },
                {
                    "name": "CYPIIA2",
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                },
                {
                    "name": "Cytochrome P450 IIA2",
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                },
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                },
                {
                    "name": "P450-UT-4",
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                },
                {
                    "name": "Testosterone 15-alpha-hydroxylase",
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                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 2A2",
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                },
                {
                    "name": "cytochrome P450, subfamily 2A, polypeptide 1",
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                },
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                    "name": "cytochrome P450, subfamily 2A, polypeptide 2",
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                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450-UT-4",
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                    "type": "synonym"
                },
                {
                    "name": "hepatic steroid hydroxylase IIA2 (CYP2A2)",
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                },
                {
                    "name": "testosterone 15-alpha-hydroxylase",
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                }
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                {
                    "name": "Cyp2a2",
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                    "name": "CYP2A21",
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                },
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                    "name": "Cyp2a-2",
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                {
                    "name": "Cyp2a2",
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                    "name": "RATCYP2A21",
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                    "id": "10941",
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                    "name": "Phospholipase D1",
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                    "name": "3.1.4.4",
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                    "name": "Choline phosphatase 1",
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                    "name": "PLD 1",
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                    "name": "PLD 1",
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                {
                    "name": "Phoshpolipase D gene 1 probably with two splicing variants A and B",
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                {
                    "name": "Phosphatidylcholine-hydrolyzing phospholipase D1",
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                {
                    "name": "choline phosphatase 1",
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                {
                    "name": "phosphatidylcholine-hydrolyzing phospholipase D1",
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                {
                    "name": "phospholipase D gene 1, probably with two splicing variants A and B",
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                {
                    "name": "phospholipase D1 isoform 2",
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                {
                    "name": "phospholipase D1, phosphatidylcholine-specific",
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                },
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                    "name": "rPLD1",
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                    "name": "rPLD1",
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                }
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                    "name": "Pld1",
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                    "name": "Pld1a",
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                },
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                    "name": "Pld1b",
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                    "name": "Pld1",
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                    "name": "Plda",
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                },
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                    "name": "Pldb",
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                    "id": "10941",
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                    "name": "Branched-chain alpha-ketoacid dehydrogenase kinase",
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                    "name": "2.7.11.1",
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                    "name": "2.7.11.4",
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                },
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                    "name": "BCKD-kinase",
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                    "name": "BCKDH kinase",
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                {
                    "name": "BCKDH kinase",
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                {
                    "name": "BCKDHKIN",
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                    "name": "BCKDHKIN",
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                    "name": "BDK",
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                },
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                    "name": "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial",
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                {
                    "name": "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial",
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                {
                    "name": "branched-chain alpha-ketoacid dehydrogenase kinase precursor",
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                {
                    "name": "branched-chain alpha-ketoacid dehydrogenase kinase",
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                    "name": "Bckdk",
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                    "name": "BDK",
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                    "name": "Bckdk",
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                    "name": "Kat8",
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                    "id": "10941",
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                    "name": "CSF-1",
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                {
                    "name": "CSF1-hERV-LTR71B fusion protein",
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                },
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                    "name": "Lanimostim",
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                },
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                    "name": "M-CSF",
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                {
                    "name": "MCSF",
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                    "name": "PG-M-CSF",
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                {
                    "name": "Proteoglycan macrophage colony-stimulating factor",
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                {
                    "name": "colony stimulating factor 1 (macrophage)",
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                    "name": "lanimostim",
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                    "name": "macrophage colony stimulating factor 1",
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                    "name": "macrophage colony-stimulating factor 1 isoform a precursor",
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                {
                    "name": "proteoglycan macrophage colony-stimulating factor",
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                    "name": "CSF1",
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                    "name": "CSF-1",
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                },
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                    "name": "CSF1",
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                },
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                    "name": "MCSF",
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                },
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                    "name": "PG-M-CSF",
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                    "id": "10941",
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                    "name": "Disks large homolog 2",
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                {
                    "name": "Channel-associated protein of synapse-110",
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                },
                {
                    "name": "Chapsyn-110",
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                },
                {
                    "name": "Postsynaptic density protein PSD-93",
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                {
                    "name": "channel-associated protein of synapse-110",
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                {
                    "name": "channel-associated protein of synapses, 110kDa",
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                {
                    "name": "discs, large homolog 2, chapsyn-110",
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                {
                    "name": "disks large homolog 2 isoform 1",
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                {
                    "name": "disks large homolog 2",
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                {
                    "name": "postsynaptic density protein PSD-93",
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                },
                {
                    "name": "protein phosphatase 1, regulatory subunit 58",
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                    "name": "DLG2",
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                    "name": "DLG2",
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                },
                {
                    "name": "PPP1R58",
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                    "name": "PSD-93",
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                },
                {
                    "name": "PSD93",
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                },
                {
                    "name": "chapsyn-110",
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                }
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                    "id": "10941",
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            ]
        },
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            "uniprot_canonical_ac": "P54849-1",
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                    "name": "Homo sapiens",
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                    "reference_species": "Homo sapiens [9606]"
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            ],
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                    "name": "Epithelial membrane protein 1",
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                    "name": "CL-20",
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                    "name": "EMP-1",
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                },
                {
                    "name": "Protein B4B",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tumor-associated membrane protein",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "epithelial membrane protein 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tumor-associated membrane protein",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "EMP1",
                    "resource": "UniProtKB",
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                },
                {
                    "name": "B4B",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "CL-20",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "EMP-1",
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                    "type": "synonym"
                },
                {
                    "name": "EMP1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TMP",
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                },
                {
                    "name": "TMP",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P08311-1",
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                {
                    "name": "Homo sapiens",
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                    "common_name": "Human",
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "Cathepsin G",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "3.4.21.20",
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                    "type": "synonym"
                },
                {
                    "name": "CG",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "cathepsin G preproprotein",
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                    "type": "synonym"
                }
            ],
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                {
                    "name": "CTSG",
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                },
                {
                    "name": "CATG",
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                },
                {
                    "name": "CG",
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                    "type": "synonym"
                },
                {
                    "name": "CTSG",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
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                }
            ]
        },
        {
            "uniprot_canonical_ac": "P04275-1",
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                    "name": "Homo sapiens",
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                    "name": "von Willebrand factor",
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                {
                    "name": "Factor VIII related antigen",
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                },
                {
                    "name": "coagulation factor VIII VWF",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "vWF",
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                    "type": "synonym"
                },
                {
                    "name": "von Willebrand antigen II",
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                    "type": "synonym"
                },
                {
                    "name": "von Willebrand factor preproprotein",
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                }
            ],
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                {
                    "name": "VWF",
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                {
                    "name": "F8VWF",
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                    "type": "synonym"
                },
                {
                    "name": "F8VWF",
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                },
                {
                    "name": "VWD",
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                    "type": "synonym"
                },
                {
                    "name": "VWF",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
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                }
            ]
        },
        {
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
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                }
            ],
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                {
                    "name": "Vascular endothelial growth factor A, long form",
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                {
                    "name": "L-VEGF",
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                    "type": "synonym"
                },
                {
                    "name": "VPF",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Vascular permeability factor",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "vascular endothelial growth factor A, long form isoform c",
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                    "type": "synonym"
                },
                {
                    "name": "vascular endothelial growth factor A, long form",
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                    "type": "synonym"
                },
                {
                    "name": "vascular endothelial growth factor A121",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "vascular endothelial growth factor A165",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "vascular permeability factor",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "VEGFA",
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                    "type": "recommended"
                },
                {
                    "name": "L-VEGF",
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                    "type": "synonym"
                },
                {
                    "name": "MVCD1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "VEGFA",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "VEGF",
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                    "type": "synonym"
                },
                {
                    "name": "VEGF",
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                    "type": "synonym"
                },
                {
                    "name": "VPF",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "72 kDa type IV collagenase",
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                    "type": "recommended"
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                {
                    "name": "3.4.24.24",
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                    "type": "synonym"
                },
                {
                    "name": "72 kDa gelatinase",
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                    "type": "synonym"
                },
                {
                    "name": "72 kDa type IV collagenase isoform 2",
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                },
                {
                    "name": "Gelatinase A",
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                    "type": "synonym"
                },
                {
                    "name": "MMP-2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Matrix metalloproteinase-2",
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                    "type": "synonym"
                },
                {
                    "name": "TBE-1",
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                },
                {
                    "name": "collagenase type IV-A",
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                    "type": "synonym"
                },
                {
                    "name": "matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)",
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                    "type": "synonym"
                },
                {
                    "name": "matrix metalloproteinase-2",
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                    "type": "synonym"
                },
                {
                    "name": "matrix metalloproteinase-II",
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                    "type": "synonym"
                },
                {
                    "name": "neutrophil gelatinase",
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                    "type": "synonym"
                }
            ],
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                    "name": "MMP2",
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                    "name": "CLG4A",
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                {
                    "name": "CLG4A",
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                },
                {
                    "name": "CLG4",
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                    "type": "synonym"
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                {
                    "name": "MMP-2",
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                    "type": "synonym"
                },
                {
                    "name": "MMP-II",
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                    "type": "synonym"
                },
                {
                    "name": "MMP2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "MONA",
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                    "type": "synonym"
                },
                {
                    "name": "TBE-1",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
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                    "name": "Homo sapiens",
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            ],
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                    "name": "Transcription factor SOX-17",
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                {
                    "name": "SRY (sex determining region Y)-box 17",
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                    "type": "synonym"
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                {
                    "name": "SRY-box 17",
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                    "type": "synonym"
                },
                {
                    "name": "SRY-related HMG-box transcription factor SOX17",
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                    "type": "synonym"
                },
                {
                    "name": "transcription factor SOX-17",
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                    "type": "synonym"
                }
            ],
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                    "name": "SOX17",
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                {
                    "name": "PPH7",
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                },
                {
                    "name": "SOX17",
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                    "type": "synonym"
                },
                {
                    "name": "VUR3",
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                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P14780-1",
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                    "name": "Homo sapiens",
                    "taxid": 9606,
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                    "reference_species": "Homo sapiens [9606]"
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            ],
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                {
                    "name": "Matrix metalloproteinase-9",
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                {
                    "name": "3.4.24.35",
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                    "type": "synonym"
                },
                {
                    "name": "92 kDa gelatinase",
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                    "type": "synonym"
                },
                {
                    "name": "92 kDa type IV collagenase",
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                },
                {
                    "name": "GELB",
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                },
                {
                    "name": "Gelatinase B",
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                },
                {
                    "name": "MMP-9",
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                {
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                    "type": "synonym"
                },
                {
                    "name": "matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)",
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                    "type": "synonym"
                },
                {
                    "name": "matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)",
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                },
                {
                    "name": "matrix metalloproteinase-9 preproprotein",
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                    "name": "type V collagenase",
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                }
            ],
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                    "name": "CLG4B",
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                },
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                    "name": "CLG4B",
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                },
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                    "name": "GELB",
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                },
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                    "name": "MANDP2",
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                {
                    "name": "MMP-9",
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                },
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                    "name": "MMP9",
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                    "type": "synonym"
                }
            ],
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                    "id": "10941",
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            ]
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                    "name": "Homo sapiens",
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            ],
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                {
                    "name": "3.4.24.80",
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                },
                {
                    "name": "MMP-14",
                    "resource": "UniProtKB",
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                },
                {
                    "name": "MMP-X1",
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                    "type": "synonym"
                },
                {
                    "name": "MT-MMP 1",
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                    "type": "synonym"
                },
                {
                    "name": "MT1-MMP",
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                },
                {
                    "name": "MT1MMP",
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                    "type": "synonym"
                },
                {
                    "name": "MTMMP1",
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                    "type": "synonym"
                },
                {
                    "name": "Membrane-type matrix metalloproteinase 1",
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                    "type": "synonym"
                },
                {
                    "name": "Membrane-type-1 matrix metalloproteinase",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "matrix metallopeptidase 14 (membrane-inserted)",
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                    "type": "synonym"
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                {
                    "name": "matrix metalloproteinase-14 preproprotein",
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                },
                {
                    "name": "matrix metalloproteinase-14",
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                },
                {
                    "name": "membrane type 1 metalloprotease",
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                    "type": "synonym"
                },
                {
                    "name": "membrane-type-1 matrix metalloproteinase",
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            ],
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                },
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                },
                {
                    "name": "MT-MMP",
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                },
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                    "name": "MT1-MMP",
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                {
                    "name": "MT1MMP",
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                },
                {
                    "name": "MTMMP1",
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                    "type": "synonym"
                },
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                    "name": "WNCHRS",
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                    "type": "synonym"
                }
            ],
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                {
                    "id": "10941",
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                }
            ]
        },
        {
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                    "name": "Homo sapiens",
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            ],
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                    "name": "Krueppel-like factor 5",
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                {
                    "name": "BTE-binding protein 2",
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                {
                    "name": "Basic transcription element-binding protein 2",
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                    "name": "Colon krueppel-like factor",
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                {
                    "name": "GC box binding protein 2",
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                },
                {
                    "name": "GC-box-binding protein 2",
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                    "type": "synonym"
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                {
                    "name": "Intestinal-enriched krueppel-like factor",
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                    "type": "synonym"
                },
                {
                    "name": "Krueppel-like factor 5 isoform 2",
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                    "type": "synonym"
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                {
                    "name": "Kruppel like factor 5",
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                    "type": "synonym"
                },
                {
                    "name": "Kruppel-like factor 5 (intestinal)",
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                    "type": "synonym"
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                {
                    "name": "Transcription factor BTEB2",
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                    "type": "synonym"
                },
                {
                    "name": "basic transcription element binding protein 2",
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                },
                {
                    "name": "colon krueppel-like factor",
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                    "type": "synonym"
                },
                {
                    "name": "colon kruppel-like factor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "epididymis secretory sperm binding protein",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "intestinal-enriched krueppel-like factor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "intestinal-enriched kruppel-like factor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "krueppel-like factor 5",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "transcription factor BTEB2",
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                    "type": "synonym"
                }
            ],
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                {
                    "name": "KLF5",
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                },
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                    "name": "BTEB2",
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                    "name": "KLF5",
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                    "id": "10941",
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                {
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                {
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                {
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                    "name": "cystatin 3",
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                {
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                    "name": "ADLDWA",
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                    "name": "ET1",
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                    "name": "HDLCQ7",
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                    "name": "PPET1",
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                    "id": "10941",
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                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q96PE2-1",
            "uniprot_ac": "Q96PE2",
            "uniprot_id": "ARHGH_HUMAN",
            "refseq_ac": "NP_055601",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Rho guanine nucleotide exchange factor 17",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "164 kDa Rho-specific guanine-nucleotide exchange factor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "164 kDa Rho-specific guanine-nucleotide exchange factor",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Rho guanine nucleotide exchange factor (GEF) 17",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Rho-specific guanine-nucleotide exchange factor 164 kDa",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Tumor endothelial marker 4",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "p164-RhoGEF",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "p164RhoGEF",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "rho guanine nucleotide exchange factor 17",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tumor endothelial marker 4",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ARHGEF17",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "ARHGEF17",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "KIAA0337",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "P164RHOGEF",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "RHOGEF17",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TEM4",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TEM4",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "p164-RhoGEF",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O00622-1",
            "uniprot_ac": "O00622",
            "uniprot_id": "CCN1_HUMAN",
            "refseq_ac": "NP_001545",
            "glycoprotein": "yes",
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "CCN family member 1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "CCN family member 1 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "CCN family member 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Cellular communication network factor 1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Cysteine-rich angiogenic inducer 61",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "IBP-10",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "IBP-10",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "IGF-binding protein 10",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "IGF-binding protein 10",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "IGFBP-10",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "IGFBP-10",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Insulin-like growth factor-binding protein 10",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Protein CYR61",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Protein GIG1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "cysteine rich angiogenic inducer 61",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cysteine-rich heparin-binding protein 61",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cysteine-rich, anigogenic inducer, 61",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "insulin-like growth factor-binding protein 10",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "protein CYR61",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CCN1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "CCN1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "CYR61",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "CYR61",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "GIG1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "GIG1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "IGFBP10",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "IGFBP10",
                    "resource": "UniProtKB",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P16035-1",
            "uniprot_ac": "P16035",
            "uniprot_id": "TIMP2_HUMAN",
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            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Metalloproteinase inhibitor 2",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "CSC-21K",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "TIMP-2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tissue inhibitor of metalloproteinases 2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 2 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "testicular secretory protein Li 57",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metalloproteinases 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TIMP2",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "CSC-21K",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "DDC8",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TIMP2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "hCG_95573",
                    "resource": "UniProtKB",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01033-1",
            "uniprot_ac": "P01033",
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            "refseq_ac": "NP_003245",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Metalloproteinase inhibitor 1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "Collagenase inhibitor",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "EPA",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Erythroid-potentiating activity",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Fibroblast collagenase inhibitor",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "TIMP-1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Tissue inhibitor of metalloproteinases 1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "epididymis secretory sperm binding protein",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "erythroid potentiating activity",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "fibroblast collagenase inhibitor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 1 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "metalloproteinase inhibitor 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "tissue inhibitor of metalloproteinases 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TIMP1",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "CLGI",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "CLGI",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "EPA",
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                    "type": "synonym"
                },
                {
                    "name": "EPO",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "HCI",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TIMP-1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TIMP1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TIMP",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "TIMP",
                    "resource": "UniProtKB",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P29474-1",
            "uniprot_ac": "P29474",
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            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "Nitric oxide synthase 3",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "1.14.13.39",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Constitutive NOS",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "EC-NOS",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "EC-NOS",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Endothelial NOS",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "NOS type III",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "NOS type III",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "NOSIII",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "NOSIII",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Nitric oxide synthase, endothelial",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "cNOS",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "cNOS",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "constitutive NOS",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "eNOS",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "endothelial NOS",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "nitric oxide synthase 3 (endothelial cell)",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "nitric oxide synthase 3 isoform 1",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "NOS3",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "ECNOS",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "NOS3",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "eNOS",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q15109-1",
            "uniprot_ac": "Q15109",
            "uniprot_id": "RAGE_HUMAN",
            "refseq_ac": "NP_001127",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Advanced glycosylation end product-specific receptor",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "Receptor for advanced glycosylation end products",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "advanced glycosylation end product-specific receptor isoform 1 precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "receptor for advanced glycation end-products",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "AGER",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "AGER",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "RAGE",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "RAGE",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "SCARJ1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "sRAGE",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q16853-1",
            "uniprot_ac": "Q16853",
            "uniprot_id": "AOC3_HUMAN",
            "refseq_ac": "NP_001264660",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Amine oxidase [copper-containing] 3",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "1.4.3.21",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Amine oxidase copper-containing 3",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Copper amine oxidase",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "HPAO",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "SSAO",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Semicarbazide-sensitive amine oxidase",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "VAP-1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Vascular adhesion protein 1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "amine oxidase [copper-containing] 3 isoform 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "amine oxidase [copper-containing] 3",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "amine oxidase, copper containing 3 (vascular adhesion protein 1)",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "copper amine oxidase",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "membrane primary amine oxidase",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "placenta copper monamine oxidase",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "semicarbazide-sensitive amine oxidase",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "AOC3",
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                    "type": "recommended"
                },
                {
                    "name": "AOC3",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "HPAO",
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                    "type": "synonym"
                },
                {
                    "name": "SSAO",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "VAP-1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "VAP1",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "VAP1",
                    "resource": "UniProtKB",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P13611-1",
            "uniprot_ac": "P13611",
            "uniprot_id": "CSPG2_HUMAN",
            "refseq_ac": "NP_001119808",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Versican core protein",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "Chondroitin sulfate proteoglycan 2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Chondroitin sulfate proteoglycan core protein 2",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "GHAP",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Glial hyaluronate-binding protein",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Large fibroblast proteoglycan",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "PG-M",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "chondroitin sulfate proteoglycan core protein 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "glial hyaluronate-binding protein",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "large fibroblast proteoglycan",
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                    "type": "synonym"
                },
                {
                    "name": "versican core protein isoform 2 precursor",
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                    "type": "synonym"
                },
                {
                    "name": "versican core protein",
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                    "type": "synonym"
                },
                {
                    "name": "versican proteoglycan",
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                }
            ],
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                {
                    "name": "VCAN",
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                    "name": "CSPG2",
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                    "name": "WGN1",
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                },
                {
                    "name": "WGN",
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                }
            ],
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                    "id": "10941",
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            ]
        },
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            ],
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                {
                    "name": "3.4.24.65",
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                {
                    "name": "ME",
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                },
                {
                    "name": "MME",
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                },
                {
                    "name": "MMP-12",
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                },
                {
                    "name": "Macrophage elastase",
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                },
                {
                    "name": "Matrix metalloproteinase-12",
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                },
                {
                    "name": "hME",
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                },
                {
                    "name": "macrophage metalloelastase preproprotein",
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                {
                    "name": "macrophage metalloelastase",
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                {
                    "name": "matrix metallopeptidase 12 (macrophage elastase)",
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                },
                {
                    "name": "matrix metalloproteinase 12 (macrophage elastase)",
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                }
            ],
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                    "id": "10941",
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            ],
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                {
                    "name": "Polycystic kidney disease 2 protein",
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                    "name": "Polycystwin",
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                },
                {
                    "name": "R48321",
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                {
                    "name": "Transient receptor potential cation channel subfamily P member 2",
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                {
                    "name": "autosomal dominant polycystic kidney disease type II protein",
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                    "name": "APKD2",
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                    "id": "10941",
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            ]
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                    "name": "polycystic kidney disease-associated protein",
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                    "name": "polycystin-1 isoform 2 precursor",
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                    "name": "eliosin",
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                    "id": "10941",
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                    "name": "Lysine N-methyltransferase 2D",
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                    "name": "histone-lysine N-methyltransferase 2D",
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                    "name": "lysine (K)-specific methyltransferase 2D",
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                    "name": "lysine N-methyltransferase 2D",
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                    "id": "10941",
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                    "name": "IFN-beta-2",
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                    "name": "interleukin-6 isoform 1 precursor",
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                    "id": "10941",
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                    "name": "CD105 antigen",
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                    "name": "endoglin isoform 3",
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                    "id": "10941",
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                {
                    "name": "collagen I, alpha-2 polypeptide",
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                {
                    "name": "collagen alpha-2(I) chain precursor",
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                    "name": "collagen alpha-2(I) chain",
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                },
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                    "name": "collagen of skin, tendon and bone, alpha-2 chain",
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                },
                {
                    "name": "collagen, type I, alpha 2",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "epididymis secretory sperm binding protein",
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                    "type": "synonym"
                },
                {
                    "name": "type I procollagen",
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                }
            ],
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                {
                    "name": "COL1A2",
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                    "name": "EDSARTH2",
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                    "name": "EDSCV",
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                    "type": "synonym"
                },
                {
                    "name": "vascular endothelial growth factor A, long form",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "vascular permeability factor",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Vegfa",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "L-VEGF",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Vegfa",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Vegf",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Vegf",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "Vpf",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q8CIZ8-1",
            "uniprot_ac": "Q8CIZ8",
            "uniprot_id": "VWF_MOUSE",
            "refseq_ac": "NP_035838",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "von Willebrand factor",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "Von Willebrand factor homolog",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "vWF",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "von Willebrand antigen II",
                    "resource": "UniProtKB",
                    "type": "synonym"
                },
                {
                    "name": "von Willebrand factor precursor",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Vwf",
                    "resource": "UniProtKB",
                    "type": "recommended"
                },
                {
                    "name": "6820430P06Rik",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "B130011O06Rik",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "C630030D09",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "F8VWF",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "VWD",
                    "resource": "RefSeq",
                    "type": "synonym"
                },
                {
                    "name": "Vwf",
                    "resource": "RefSeq",
                    "type": "synonym"
                }
            ],
            "evidence": [
                {
                    "id": "10941",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:10941"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.10941"
}