{ "disease_id": "DOID:1024", "recommended_name": { "id": "DOID:1024", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1024", "name": "leprosy", "description": "A primary bacterial infectious disease that results_in infection located_in superficial peripheral nerves, located_in skin, located_in mucous membranes of the upper respiratory tract, located_in anterior chamber of the eyes, or located_in testes, has_material_basis_in Mycobacterium leprae, which is transmitted_by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. The infection has_symptom skin lesions, has_symptom sensory loss, has_symptom motor loss and has_symptom eye damage." }, "synonyms": [ { "id": "MONDO:0011860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "name": "leprosy, susceptibility to, 2", "description": "" }, { "id": "MONDO:0011860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "name": "LPRS2", "description": "" }, { "id": "MONDO:0011860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "name": "leprosy, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "name": "leprosy, susceptibility to, 1", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "name": "LPRS1", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": 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"id": "DOID:1025", "label": "tuberculoid leprosy", "link_status": true, "children": [] }, { "id": "DOID:10887", "label": "lepromatous leprosy", "link_status": true, "children": [] } ], "id_list": [ "DOID:1024", "DOID:1025", "DOID:10887" ], "unlinked_id_list": [], "crossref": [ { "id": "DOID:1024", "database": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1024", "categories": [] }, { "id": "MONDO:0011860", "database": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "categories": [] }, { "id": "MONDO:0012358", "database": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "categories": [] }, { "id": "MONDO:0013257", "database": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013257", "categories": [] } ], "proteins": [ { "uniprot_canonical_ac": "A9ZPF0-1", "uniprot_ac": "A9ZPF0", "uniprot_id": "A9ZPF0_DANRE", "refseq_ac": "NP_001108540", "glycoprotein": "no", "species": [ { "name": "Danio rerio", "taxid": 7955, 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"UniProtKB", "type": "synonym" }, { "name": "TNF alpha", "resource": "UniProtKB", "type": "synonym" }, { "name": "Tnf-alpha", "resource": "RefSeq", "type": "synonym" }, { "name": "Tnf-alpha", "resource": "UniProtKB", "type": "synonym" }, { "name": "tnfa-like", "resource": "RefSeq", "type": "synonym" }, { "name": "tnfa-like", "resource": "UniProtKB", "type": "synonym" }, { "name": "tnfb", "resource": "RefSeq", "type": "synonym" }, { "name": "tnf", "resource": "RefSeq", "type": "synonym" }, { "name": "tnf", "resource": "UniProtKB", "type": "synonym" } ], "evidence": [ { "id": "1024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1024" } ] }, { "uniprot_canonical_ac": "Q4W897-1", "uniprot_ac": "Q4W897", "uniprot_id": "Q4W897_DANRE", "refseq_ac": "NP_001019992", "glycoprotein": "no", "species": [ { "name": "Danio rerio", "taxid": 7955, "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "protein_names": [ { "name": 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"synonym" }, { "name": "si:dz48c11.4", "resource": "UniProtKB", "type": "synonym" }, { "name": "zgc:123061", "resource": "RefSeq", "type": "synonym" }, { "name": "zgc:123061", "resource": "UniProtKB", "type": "synonym" } ], "evidence": [ { "id": "1024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1024" } ] }, { "uniprot_canonical_ac": "A0A8M2B5P7-1", "uniprot_ac": "A0A8M2B5P7", "uniprot_id": "A0A8M2B5P7_DANRE", "refseq_ac": "XP_005159251", "glycoprotein": "no", "species": [ { "name": "Danio rerio", "taxid": 7955, "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "protein_names": [ { "name": "Major histocompatibility complex class II DBB isoform X1", "resource": "UniProtKB", "type": "synonym" }, { "name": "major histocompatibility complex class II DBB isoform X1", "resource": "RefSeq", "type": "synonym" } ], "gene_names": [ { "name": "mhc2dbb", "resource": "UniProtKB", "type": "recommended" }, { "name": 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