{
    "title": "The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase.",
    "journal": "Biochemical and biophysical research communications",
    "date": "1999",
    "authors": "Howlett CJ, Bisson SA, Resek ME, Tigley AW, Robbins SM",
    "reference": {
        "type": "PubMed",
        "id": "10092522",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10092522"
    },
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        {
            "uniprot_canonical_ac": "P22682-1",
            "protein_name": "E3 ubiquitin-protein ligase CBL",
            "gene_name": "Cbl",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P08631-1",
            "protein_name": "Tyrosine-protein kinase HCK",
            "gene_name": "HCK",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P22681-1",
            "protein_name": "E3 ubiquitin-protein ligase CBL",
            "gene_name": "CBL",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
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                    "url": "https://www.uniprot.org/uniprotkb/P22682"
                }
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            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
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        {
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            "end_pos": 522,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Constitutively activated kinase, leading to cellular transformation.",
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                    "url": "https://www.uniprot.org/uniprotkb/P08631"
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            "end_pos": 731,
            "kinase_uniprot_canonical_ac": "P00533-1",
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            "comment": "",
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                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681"
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                },
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                {
                    "database": "PubMed",
                    "id": "9890970",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9890970"
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            ],
            "site_lbl": "Tyr731",
            "uniprot_canonical_ac": "P22681-1"
        },
        {
            "start_pos": 731,
            "end_pos": 731,
            "kinase_uniprot_canonical_ac": "P06241-1",
            "kinase_gene_name": "FYN",
            "residue": "Tyr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P22681",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681"
                },
                {
                    "database": "PubMed",
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                    "url": "https://pubmed.ncbi.nlm.nih.gov/10092522"
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                {
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                {
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                    "id": "11239464",
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    "abstract": "",
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