{
    "title": "gp49B1 inhibits IgE-initiated mast cell activation through both immunoreceptor tyrosine-based inhibitory motifs, recruitment of src homology 2 domain-containing phosphatase-1, and suppression of early and late calcium mobilization.",
    "journal": "The Journal of biological chemistry",
    "date": "1999",
    "authors": "Lu-Kuo JM, Joyal DM, Austen KF, Katz HR",
    "reference": {
        "type": "PubMed",
        "id": "10026201",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10026201"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q64281-1",
            "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 4A",
            "gene_name": "Gm49339; Lilrb4a",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P29351-1",
            "protein_name": "Tyrosine-protein phosphatase non-receptor type 6",
            "gene_name": "Ptpn6",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P35235-2",
            "protein_name": "Tyrosine-protein phosphatase non-receptor type 11",
            "gene_name": "Ptpn11",
            "tax_name": "Mouse"
        }
    ],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q64281",
                    "url": "https://www.uniprot.org/uniprotkb/Q64281"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 300,
            "end_pos": 300,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Partially suppresses inhibition of mast cell activation. Abolishes inhibition of mast cell activation; when associated with F-322.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q64281",
                    "url": "https://www.uniprot.org/uniprotkb/Q64281"
                },
                {
                    "database": "PubMed",
                    "id": "10026201",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10026201"
                }
            ],
            "uniprot_canonical_ac": "Q64281-1"
        },
        {
            "start_pos": 322,
            "end_pos": 322,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Partially suppresses inhibition of mast cell activation. Abolishes inhibition of mast cell activation; when associated with F-300.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q64281",
                    "url": "https://www.uniprot.org/uniprotkb/Q64281"
                },
                {
                    "database": "PubMed",
                    "id": "10026201",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10026201"
                }
            ],
            "uniprot_canonical_ac": "Q64281-1"
        }
    ],
    "record_id": "pubmed.10026201",
    "abstract": "",
    "glycosylation": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}