{
    "uniprot_canonical_ac": "A0A1D5PLP7-1",
    "uniprot_ac": "A0A1D5PLP7",
    "uniprot_id": "A0A1D5PLP7_CHICK",
    "mass": {
        "chemical_mass": 26765.0,
        "monoisotopic_mass": 26765.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "TREM-A1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7",
            "id": "A0A1D5PLP7"
        },
        {
            "name": "TREM2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7",
            "id": "A0A1D5PLP7"
        },
        {
            "name": "TREM2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7",
            "id": "A0A1D5PLP7"
        }
    ],
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        {
            "name": "Triggering receptor expressed on myeloid cells 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7/entry#names_and_taxonomy",
            "id": "A0A1D5PLP7"
        },
        {
            "name": "Triggering receptor expressed on monocytes 2",
            "resource": "UniProtKB",
            "type": "synonym",
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            "id": "A0A1D5PLP7"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Gallus gallus",
            "taxid": 9031,
            "evidence": [
                {
                    "database": "UniProtKB",
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                    "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7"
                }
            ],
            "common_name": "Chicken",
            "glygen_name": "Chicken",
            "reference_species": "Gallus gallus [9031]"
        }
    ],
    "gene": [
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            "name": "TREM2",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7",
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                "evidence": [
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                        "id": "ENSGALG00010027674",
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                    }
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    "crossref": [
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            "id": "A0A1D5PLP7",
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            "database": "AlphaFoldDB",
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        {
            "id": "ENSGALG00000023781",
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        {
            "id": "cd05716",
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            "categories": [
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            ]
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            "id": "419920",
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            "database": "GeneID",
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            ]
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        {
            "id": "IPR003599",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007110",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013106",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR052314",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR052314",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
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        {
            "id": "gga:419920",
            "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419920",
            "database": "KEGG Pathway",
            "categories": [
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            ]
        },
        {
            "id": "CAPSFRH",
            "url": "https://omabrowser.org/oma/group/CAPSFRH/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A1D5PLP7",
            "url": "https://www.orthodb.org/?gene=A0A1D5PLP7",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "Q2YHU4",
            "url": "https://www.orthodb.org/?gene=Q2YHU4",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR16423",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16423",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR16423:SF6",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16423:SF6",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07686",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-198933",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A1D5PLP7",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1D5PLP7-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q2YHU4",
            "url": "https://www.uniprot.org/uniprotkb/Q2YHU4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q2YHU4-1",
            "url": "https://www.uniprot.org/uniprotkb/Q2YHU4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MFSWLPWDWTCKAVKPSLEPRSGTKQQDEASCTAENITTVYGMEGGTISVNCTYNPRQQRWREKSWCKQIDGSKCQHVVSARRFWLPFLKNRNGTTSISDNIQDGVLTVTMRRLRKQDAGLYQCKTNYLGETNTLRKVQVDVLTAVLETQIPEEPSAVQSTSSIPPKADFTVFYIIAGLLATKFVVAVLIFIISNSRKNRETEQNKPSLNEHQVLRFPGDLVEHAHGGISPSWENTA",
        "length": 237,
        "header": "tr|A0A1D5PLP7-1|A0A1D5PLP7_CHICK Isoform 1 of Triggering receptor expressed on myeloid cells 2  OS=Gallus gallus OX=9031 GN=TREM2 PE=4 SV=2 CANONICAL=A0A1D5PLP7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A1D5PLP7-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7/entry#A0A1D5PLP7-1",
            "sequence": {
                "sequence": "MFSWLPWDWTCKAVKPSLEPRSGTKQQDEASCTAENITTVYGMEGGTISVNCTYNPRQQRWREKSWCKQIDGSKCQHVVSARRFWLPFLKNRNGTTSISDNIQDGVLTVTMRRLRKQDAGLYQCKTNYLGETNTLRKVQVDVLTAVLETQIPEEPSAVQSTSSIPPKADFTVFYIIAGLLATKFVVAVLIFIISNSRKNRETEQNKPSLNEHQVLRFPGDLVEHAHGGISPSWENTA",
                "length": 237,
                "header": "tr|A0A1D5PLP7-1|A0A1D5PLP7_CHICK Isoform 1 of Triggering receptor expressed on myeloid cells 2  OS=Gallus gallus OX=9031 GN=TREM2 PE=4 SV=2 CANONICAL=A0A1D5PLP7-1"
            },
            "locus": {
                "chromosome": "26",
                "start_pos": 4792168,
                "end_pos": 4789224,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010067090.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010067090.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010041011.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010041011.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q2YHU4-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7/entry#Q2YHU4-1",
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                "length": 221,
                "header": "tr|Q2YHU4-1|A0A1D5PLP7_CHICK Computationally mapped isoform of Triggering receptor expressed on myeloid cells 2  OS=Gallus gallus OX=9031 GN=TREM2 PE=4 SV=1 CANONICAL=A0A1D5PLP7-1"
            },
            "locus": {
                "chromosome": "26",
                "start_pos": 4793609,
                "end_pos": 4789224,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010067095.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010067095.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010041015.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010041015.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The chicken immunoregulatory receptor families SIRP, TREM, and CMRF35/CD300L.",
            "journal": "Immunogenetics",
            "date": "2006",
            "authors": "Viertlboeck Birgit C, Schmitt Ramona, G\u00f6bel Thomas W",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q2YHU4",
                    "url": "https://www.uniprot.org/uniprotkb/Q2YHU4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16493555",
                    "url": "https://glygen.org/publication/PubMed/16493555"
                }
            ]
        }
    ],
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        {
            "id": "gga:419920",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419920",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-GGA-198933",
            "name": "",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933",
            "resource": "Reactome",
            "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A5G2R144-1",
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                "length": 235
            },
            "evidence": [
                {
                    "id": "A0A1D5PLP7",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PLP7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "A0A8I6A303-1",
            "protein_name": "Triggering receptor expressed on myeloid cells 2",
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            "tax_id": 10116,
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                "length": 232
            },
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                {
                    "id": "A0A1D5PLP7",
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                    "database": "OMA"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q99NH8-1",
            "protein_name": "Triggering receptor expressed on myeloid cells 2",
            "gene_name": "Trem2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MGPLHQFLLLLITALSQALNTTVLQGMAGQSLRVSCTYDALKHWGRRKAWCRQLGEEGPCQRVVSTHGVWLLAFLKKRNGSTVIADDTLAGTVTITLKNLQAGDAGLYQCQSLRGREAEVLQKVLVEVLEDPLDDQDAGDLWVPEESSSFEGAQVEHSTSRNQETSFPPTSILLLLACVLLSKFLAASILWAVARGRQKPGTPVVRGLDCGQDAGHQLQILTGPGGT",
                "length": 227
            },
            "evidence": [
                {
                    "id": "A0A1D5PLP7",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PLP7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9NZC2-1",
            "protein_name": "Triggering receptor expressed on myeloid cells 2",
            "gene_name": "TREM2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
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                "sequence": "MEPLRLLILLFVTELSGAHNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLACIFLIKILAASALWAAAWHGQKPGTHPPSELDCGHDPGYQLQTLPGLRDT",
                "length": 230
            },
            "evidence": [
                {
                    "id": "A0A1D5PLP7",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PLP7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PLP7",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell surface",
                        "id": "GO:0009986",
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                                "database": "UniProtKB",
                                "id": "A0A1D5PLP7",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7"
                            }
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                ]
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            {
                "name": "Molecular Function",
                "total": 1,
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                    {
                        "name": "signaling receptor activity",
                        "id": "GO:0038023",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PLP7",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLP7"
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                        "pmid": ""
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            "start_pos": 36,
            "end_pos": 38,
            "annotation": "n_glycosylation_sequon"
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        {
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            "end_pos": 53,
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            "end_pos": 95,
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    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [
        {
            "pdb_id": "AF-A0A1D5PLP7-F1",
            "pdb_chain": "global",
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            "resolution": -1.0,
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            "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLP7"
        }
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    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
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    "sequence_features": {
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        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
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                "end_pos": 38
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                "start_pos": 51,
                "end_pos": 53
            },
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                "start_pos": 93,
                "end_pos": 95
            }
        ]
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