{ "uniprot_canonical_ac": "A0A1D5PLB7-1", "uniprot_ac": "A0A1D5PLB7", "uniprot_id": "A0A1D5PLB7_CHICK", "mass": { "chemical_mass": 161305.0, "monoisotopic_mass": 161305.0 }, "refseq": {}, "gene_names": [ { "name": "WHSC1L1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7", "id": "A0A1D5PLB7" } ], "protein_names": [ { "name": "Histone-lysine N-methyltransferase NSD3", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#names_and_taxonomy", "id": "A0A1D5PLB7" }, { "name": "2.1.1.370", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#names_and_taxonomy", "id": "A0A1D5PLB7" }, { "name": "2.1.1.371", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#names_and_taxonomy", "id": "A0A1D5PLB7" }, { "name": "Nuclear SET domain-containing protein 3", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#names_and_taxonomy", "id": "A0A1D5PLB7" } ], "function": [ { "annotation": "Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7#function" }, { "database": "UniProtKB", "id": "ARBA00056539", "url": "https://www.uniprot.org/uniprotkb/ARBA00056539#function" }, { "database": "UniProtKB", "id": "A0A3Q2UBA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBA0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WHSC1L1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000003299", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003299", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15649", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15649", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15652", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15652", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19212", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19212", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20163", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20163", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20166", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20166", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426778", "url": "https://www.ncbi.nlm.nih.gov/gene/426778", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLB7", "url": "https://www.orthodb.org/?gene=A0A1D5PLB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UBA0", "url": "https://www.orthodb.org/?gene=A0A3Q2UBA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15999:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15999:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF17907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17907", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF17982", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17982", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF22908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22908", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF23004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23004", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF23011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23011", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_015152898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152898", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "64448", "url": "https://www.rhea-db.org/rhea/64448", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64452", "url": "https://www.rhea-db.org/rhea/64452", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDASSDIAEDGGQTPYEAALQQGFQYPTPTAEDLPPIANGYPATINMYEPQAKFQTYSQYPNGSANGFGTVRNFSPPEYYHMENSNARPHEVLEKPSPPQPPPPPPPVSQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEYAKAKHEGRKEKRKKSSKHDSSRSEERKSHKIPKLEPEEQNRPNERLSMLSERPREDALLEEAPVQQFLPSLPTQVSHDIKFQVGDLVWSKVGTYPWWPCMVSCDPQLDVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEQLLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKEPEEVLSKAKKTTASKSETKKNRRPKPALNTQTEHANVVTGSPSSAELRRQSQRRQSSAEEEEPPPVKIAWKTAAARKSLPASITMHNLDLQKCNMSPVVKIEQVFALQNAAGDGKLIDQFVYSTKGVGNKAEISVKGQEKLNSSSSQRNEKATCNVQNASSPETTSGSAGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVEMVPLTAVKTGLQKGASEISDSCKPLKKRSRASTDVELTSSAYRDASDSDSRGLNDLQGSFGKRSDSPSAAVDADASDVQSVDSSLSRRGTGTNKKDTVCQICESSGESLVSCEGECCSTFHMECLGLKAMPEEKFFCTECKNGEHTCFSCKLPGKDVKRCSVSACGKFYHEACVRKFATALFESRGFRCPQHCCSACSVDKDIHKASKGRMVRCFRCPIAYHSGDGCIAAGSLFVSSHILICSNHSKRNHSSSAVNVGFCFVCARGLVVQDHSDPLFSSYAYKSHYLLNESNRAELMKLPMIPPPSSASKKKCEKGGKLLCCESCPASFHPECLNIDMPEGCWNCNDCKAGKKLRYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDIGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIERNSRKPPPYKHIKSNKVIGKVQIQVADLSEIPRCNCKPSDENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRLYPDAEIIKTDRRGWGLRTKRNIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDIRVGLFALCDIPAGMELTFNYNLDCLGNGRTECHCGAENCSGFLGVRPKTAFATANEEKVKNAKLKQKKRKIKTEQKQMHEDNCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPFGKWECPWHQCDICSSPAVSFCEFCPHSFCKDHEKGALLASALDGRLCCSTHDPKSPVAPEYWNKIKCKLEPQNPVEEAKE", "length": 1436, "header": "tr|A0A1D5PLB7-1|A0A1D5PLB7_CHICK Isoform 1 of Histone-lysine N-methyltransferase NSD3 OS=Gallus gallus OX=9031 GN=WHSC1L1 PE=4 SV=3 CANONICAL=A0A1D5PLB7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#A0A1D5PLB7-1", "sequence": { "sequence": "MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDASSDIAEDGGQTPYEAALQQGFQYPTPTAEDLPPIANGYPATINMYEPQAKFQTYSQYPNGSANGFGTVRNFSPPEYYHMENSNARPHEVLEKPSPPQPPPPPPPVSQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEYAKAKHEGRKEKRKKSSKHDSSRSEERKSHKIPKLEPEEQNRPNERLSMLSERPREDALLEEAPVQQFLPSLPTQVSHDIKFQVGDLVWSKVGTYPWWPCMVSCDPQLDVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEQLLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKEPEEVLSKAKKTTASKSETKKNRRPKPALNTQTEHANVVTGSPSSAELRRQSQRRQSSAEEEEPPPVKIAWKTAAARKSLPASITMHNLDLQKCNMSPVVKIEQVFALQNAAGDGKLIDQFVYSTKGVGNKAEISVKGQEKLNSSSSQRNEKATCNVQNASSPETTSGSAGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVEMVPLTAVKTGLQKGASEISDSCKPLKKRSRASTDVELTSSAYRDASDSDSRGLNDLQGSFGKRSDSPSAAVDADASDVQSVDSSLSRRGTGTNKKDTVCQICESSGESLVSCEGECCSTFHMECLGLKAMPEEKFFCTECKNGEHTCFSCKLPGKDVKRCSVSACGKFYHEACVRKFATALFESRGFRCPQHCCSACSVDKDIHKASKGRMVRCFRCPIAYHSGDGCIAAGSLFVSSHILICSNHSKRNHSSSAVNVGFCFVCARGLVVQDHSDPLFSSYAYKSHYLLNESNRAELMKLPMIPPPSSASKKKCEKGGKLLCCESCPASFHPECLNIDMPEGCWNCNDCKAGKKLRYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDIGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIERNSRKPPPYKHIKSNKVIGKVQIQVADLSEIPRCNCKPSDENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRLYPDAEIIKTDRRGWGLRTKRNIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDIRVGLFALCDIPAGMELTFNYNLDCLGNGRTECHCGAENCSGFLGVRPKTAFATANEEKVKNAKLKQKKRKIKTEQKQMHEDNCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPFGKWECPWHQCDICSSPAVSFCEFCPHSFCKDHEKGALLASALDGRLCCSTHDPKSPVAPEYWNKIKCKLEPQNPVEEAKE", "length": 1436, "header": "tr|A0A1D5PLB7-1|A0A1D5PLB7_CHICK Isoform 1 of Histone-lysine N-methyltransferase NSD3 OS=Gallus gallus OX=9031 GN=WHSC1L1 PE=4 SV=3 CANONICAL=A0A1D5PLB7-1" }, "locus": { "chromosome": "22", "start_pos": 2485942, "end_pos": 2464370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043137.1", "url": "https://www.ensembl.org/id/ENSGALT00010043137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025616.1", "url": "https://www.ensembl.org/id/ENSGALP00010025616.1" } ] } }, { "isoform_ac": "A0A3Q2UBA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#A0A3Q2UBA0-1", "sequence": { "sequence": "MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDASSDIAEDGGQTPYEAALQQGFQYPTPTAEDLPPIANGYPATINMYEPQAKFQTYSQYPNGSANGFGTVRNFSPPEYYHMENSNARPHEVLEKPSPPQPPPPPPPVSQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEYAKAKHEGRKEKRKKSSKHDSSRSEERKSHKIPKLEPEEQNRPNERLSMLSERPREDALLEEAPVQQFLPSLPTQVSHDIKFQVGDLVWSKVGTYPWWPCMVSCDPQLDVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEQLLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKEPEEVLSKAKKTTASKSETKKNRRPKPALNTQTEHANVVTGSPSSAELRRQSQRRQSSAEEEEPPPVKIAWKTAAARKSLPASITMHNLDLQKCNMSPVVKIEQVFALQNAAGDGKLIDQFVYSTKGVGNKAEISVKGQEKLNSSSSQRNEKATCNVQNASSPETTSGSAGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVEMVPLTAVKTGLQKGASEISDSCKPLKKRSRASTDVELTSSAYRDASDSDSRGLNDLQGSFGKRSDSPSAAVDADASDVQSVDSSLSRRGTGTNKKDTVCQICESSGESLVSCEGECCSTFHMECLGLKAMPEEKFFCTECKNGEHTCFSCKLPGKDVKRCSVSACGKFYHEACVRKFATALFESRGFRCPQHCCSACSVDKDIHKASKGRMVRCFRCPIAYHSGDGCIAAGSLFVSSHILICSNHSKRNHSSSAVNVGFCFVCARGGKLLCCESCPASFHPECLNIDMPEGCWNCNDCKAGKKLRYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDIGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIERNSRKPPPYKHIKSNKVIGKVQIQVADLSEIPRCNCKPSDENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRLYPDAEIIKTDRRGWGLRTKRNIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDIRVGLFALCDIPAGMELTFNYNLDCLGNGRTECHCGAENCSGFLGVRPKTAFATANEEKVKNAKLKQKKRKIKTEQKQMHEDNCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPFGKWECPWHQCDICSSPAVSFCEFCPHSFCKDHEKGALLASALDGRLCCSTHDPKSPVAPEYWNKIKCKLEPQNPVEEAKE", "length": 1386, "header": "tr|A0A3Q2UBA0-1|A0A3Q2UBA0_CHICK Computationally mapped isoform of Histone-lysine N-methyltransferase NSD3 OS=Gallus gallus OX=9031 GN=WHSC1L1 PE=4 SV=1 CANONICAL=A0A1D5PLB7-1" }, "locus": { "chromosome": "22", "start_pos": 2485942, "end_pos": 2464370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043143.1", "url": "https://www.ensembl.org/id/ENSGALT00010043143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025621.1", "url": "https://www.ensembl.org/id/ENSGALP00010025621.1" } ] } }, { "isoform_ac": "A0A8V0ZAU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7/entry#A0A8V0ZAU9-1", "sequence": { "sequence": "MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDASSDIAEDGGQTPYEAALQQGFQYPTPTAEDLPPIANGYPATINMYEPQAKFQTYSQYPNGSANGFGTVRNFSPPEYYHMENSNARPHEVLEKPSPPQPPPPPPPVSQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEYAKAKHEGRKEKRKKSSKHDSSRSEERKSHKIPKLEPEEQNRPNERLSMLSERPREDALLEEAPVQQFLPSLPTQVSHDIKFQVGDLVWSKVGTYPWWPCMVSCDPQLDVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEQLLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKEPEEVLSKAKKTTASKSETKKNRRPKPALNTQTEHANVVTGSPSSAELRRQSQRRQSSAEEEEPPPVKIAWKTAAARKSLPASITMHNLDLQKCNMSPVVKIEQVFALQNAAGDGKLIDQFVYSTKGVGNKAEISVKGQEKLNSSSSQRNEKATCNVQNASSPETTSGSAGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQYQSGYGKWELNDARLLTNLPCFL", "length": 624, "header": "tr|A0A8V0ZAU9-1|A0A8V0ZAU9_CHICK Computationally mapped isoform of Nuclear receptor binding SET domain protein 3 OS=Gallus gallus OX=9031 GN=WHSC1L1 PE=4 SV=1 CANONICAL=A0A1D5PLB7-1" }, "locus": { "chromosome": "22", "start_pos": 2485942, "end_pos": 2478838, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043125.1", "url": "https://www.ensembl.org/id/ENSGALT00010043125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025609.1", "url": "https://www.ensembl.org/id/ENSGALP00010025609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": 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"pmid": "" }, { "name": "histone H3K27 trimethyltransferase activity", "id": "GO:0140951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140951", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7" } ], "pmid": "" }, { "name": "histone H3K4 dimethyltransferase activity", "id": "GO:0140946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140946", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7" } ], "pmid": "" }, { "name": "histone H3K27 dimethyltransferase activity", "id": "GO:0140952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140952", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB7" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": 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