{ "uniprot_canonical_ac": "A0A1D5PL38-1", "uniprot_ac": "A0A1D5PL38", "uniprot_id": "A0A1D5PL38_CHICK", "mass": { "chemical_mass": 87903.0, "monoisotopic_mass": 87903.0 }, "refseq": {}, "gene_names": [ { "name": "ALDH18A1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38", "id": "A0A1D5PL38" } ], "protein_names": [ { "name": "Delta-1-pyrroline-5-carboxylate synthase", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#names_and_taxonomy", "id": "A0A1D5PL38" }, { "name": "Gamma-glutamyl kinase", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#names_and_taxonomy", "id": "A0A1D5PL38" }, { "name": "Glutamate-5-semialdehyde dehydrogenase", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#names_and_taxonomy", "id": "A0A1D5PL38" }, { "name": "Glutamyl-gamma-semialdehyde dehydrogenase", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#names_and_taxonomy", "id": "A0A1D5PL38" } ], "function": [ { "annotation": "Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XCA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCA9#function" }, { "database": "UniProtKB", "id": "ARBA00055158", "url": "https://www.uniprot.org/uniprotkb/ARBA00055158#function" }, { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38#function" }, { "database": "UniProtKB", "id": "A0A8V0XCJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCJ1#function" }, { "database": "UniProtKB", "id": "A0A1L1RR71", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR71#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALDH18A1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38", "locus": { "chromosome": "6", "start_pos": 36156087, "end_pos": 36110624, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001692", "url": "https://www.ensembl.org/id/ENSGALG00010001692" } ] } } ], "crossref": [ { "id": "A0A1D5PL38", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PL38", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034655", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034655", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04256", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04256", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07079", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07079", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423976", "url": "https://www.ncbi.nlm.nih.gov/gene/423976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PPMFIVD", "url": "https://omabrowser.org/oma/group/PPMFIVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PL38", "url": "https://www.orthodb.org/?gene=A0A1D5PL38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RR71", "url": "https://www.orthodb.org/?gene=A0A1L1RR71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9K4", "url": "https://www.orthodb.org/?gene=A0A8V0X9K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCA9", "url": "https://www.orthodb.org/?gene=A0A8V0XCA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCJ1", "url": "https://www.orthodb.org/?gene=A0A8V0XCJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11063:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11063:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00696", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-8964539", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964539", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "XP_015144486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14877", "url": "https://www.rhea-db.org/rhea/14877", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19541", "url": "https://www.rhea-db.org/rhea/19541", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PL38-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RR71", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RR71-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCQAALNPLVRSPGWCFVLSPHAIAAVSRFYLPHHTQSLRNESIRCWSNIPFITMPLSRAHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQSQLKDMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIINTNDAVVPPPEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKISGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMSRAGGRTLAALQPEQRAEIIYRLADLLTDQREEILLANKKDLEEAENKGRLALPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRIIRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVSALAIASGNGLLLKGGKEAAYSNQILHHLTQEALSIHGVKDAVQLVNTREEVEDLCRLDKLIDLIIPRGSSQLVRNIQKAAKGIPVMGHSEGICHVYVDTDASVEKVTRIIRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSVQEAVEHIHKYGSSHTDVIITENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGIEGLLTTKWLLRGDNHVVSDFSEHGSMKYLHENLPLPHRNTS", "length": 802, "header": "tr|A0A1D5PL38-1|A0A1D5PL38_CHICK Isoform 1 of Delta-1-pyrroline-5-carboxylate synthase OS=Gallus gallus OX=9031 GN=ALDH18A1 PE=1 SV=2 CANONICAL=A0A1D5PL38-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PL38-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#A0A1D5PL38-1", "sequence": { "sequence": "MSCQAALNPLVRSPGWCFVLSPHAIAAVSRFYLPHHTQSLRNESIRCWSNIPFITMPLSRAHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQSQLKDMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIINTNDAVVPPPEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKISGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMSRAGGRTLAALQPEQRAEIIYRLADLLTDQREEILLANKKDLEEAENKGRLALPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRIIRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVSALAIASGNGLLLKGGKEAAYSNQILHHLTQEALSIHGVKDAVQLVNTREEVEDLCRLDKLIDLIIPRGSSQLVRNIQKAAKGIPVMGHSEGICHVYVDTDASVEKVTRIIRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSVQEAVEHIHKYGSSHTDVIITENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGIEGLLTTKWLLRGDNHVVSDFSEHGSMKYLHENLPLPHRNTS", "length": 802, "header": "tr|A0A1D5PL38-1|A0A1D5PL38_CHICK Isoform 1 of Delta-1-pyrroline-5-carboxylate synthase OS=Gallus gallus OX=9031 GN=ALDH18A1 PE=1 SV=2 CANONICAL=A0A1D5PL38-1" }, "locus": { "chromosome": "6", "start_pos": 36155368, "end_pos": 36122746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003895.1", "url": "https://www.ensembl.org/id/ENSGALT00010003895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002199.1", "url": "https://www.ensembl.org/id/ENSGALP00010002199.1" } ] } }, { "isoform_ac": "A0A1L1RR71-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#A0A1L1RR71-1", "sequence": { "sequence": "MPSQPFPVSPSSFLLYHKQENSLAASNLPHHTQSLRNESIRCWSNIPFITMPLSRAHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQSQLKDMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIINTNDAVVPPPEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKISGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMSRAGGRTLAALQPEQRAEIIYRLADLLTDQREEILLANKKDLEEAENKGRLALPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRIIRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVSALAIASGNGLLLKGGKEAAYSNQILHHLTQEALSIHGVKDAVQLVNTREEVEDLCRLDKLIDLIIPRGSSQLVRNIQKAAKGIPVMGHSEGICHVYVDTDASVEKVTRIIRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSVQEAVEHIHKYGSSHTDVIITENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGIEGLLTTKWLLRGDNHVVSDFSEHGSMKYLHENLPLPHRNTS", "length": 797, "header": "tr|A0A1L1RR71-1|A0A1L1RR71_CHICK Computationally mapped isoform of Delta-1-pyrroline-5-carboxylate synthase OS=Gallus gallus OX=9031 GN=ALDH18A1 PE=1 SV=1 CANONICAL=A0A1D5PL38-1" }, "locus": { "chromosome": "6", "start_pos": 36155368, "end_pos": 36122813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003892.1", "url": "https://www.ensembl.org/id/ENSGALT00010003892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002196.1", "url": "https://www.ensembl.org/id/ENSGALP00010002196.1" } ] } }, { "isoform_ac": "A0A8V0X9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#A0A8V0X9K4-1", "sequence": { "sequence": "MSCQAALNPLVRSPGWCFVLSPHAIAAVSRFYLPHHTQSLRNESIRCWSNIPFITMPLSRAHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQSQLKDMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIINTNDAVVPPPEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKISGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMSRAGGRTLAALQPEQRAEIIYRLADLLTDQREEILLANKKDLEEAENKGRLALPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRIIRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVSALAIASGNGLLLKGGKEAAYSNQILHHLTQEALSIHGVKDAVQLVNTREEVEDLCRLDKLIDLIIPRGSSQLVRNIQKAAKGIPVMGHSEGICHVYVDTDASVEKVTRIIRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVSWLLGLSLEVCDALDSPYKVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSVQEAVEHIHKYGSSHTDVIITENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGIEGLLTTKWLLRGDNHVVSDFSEHGSMKYLHENLPLPHRNTS", "length": 822, "header": "tr|A0A8V0X9K4-1|A0A8V0X9K4_CHICK Computationally mapped isoform of Delta-1-pyrroline-5-carboxylate synthase OS=Gallus gallus OX=9031 GN=ALDH18A1 PE=1 SV=1 CANONICAL=A0A1D5PL38-1" }, "locus": { "chromosome": "6", "start_pos": 36155368, "end_pos": 36122746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003887.1", "url": "https://www.ensembl.org/id/ENSGALT00010003887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002191.1", "url": "https://www.ensembl.org/id/ENSGALP00010002191.1" } ] } }, { "isoform_ac": "A0A8V0XCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#A0A8V0XCA9-1", "sequence": { "sequence": "MSCQAALNPLVRSPGWCFVLSPHAIAAVSRFYLPHHTQSLRNESIRCWSNIPFITMPLSRAHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQSQLKDMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIINTNDAVVPPPEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKISGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMSRAGGRTLAALQPEQRAEIIYRLADLLTDQREEILLANKKDLEEAENKGRLALPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRIIRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVSALAIASGNGLLLKGGKEAAYSNQILHHLTQEALSIHGVKDAVQLVNTREEVEDLCRLDKLIDLIIPRGSSQLVRNIQKAAKGIPVMGHSEGICHVYVDTDASVEKVTRIIRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSVQEAVEHIHKYGSSHTDVIITENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGIEGLLTTKWLLRGDNHVVSDFSEHGSMKYLHENLPLPHRNTS", "length": 799, "header": "tr|A0A8V0XCA9-1|A0A8V0XCA9_CHICK Computationally mapped isoform of Delta-1-pyrroline-5-carboxylate synthase OS=Gallus gallus OX=9031 GN=ALDH18A1 PE=1 SV=1 CANONICAL=A0A1D5PL38-1" }, "locus": { "chromosome": "6", "start_pos": 36155368, "end_pos": 36122746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003878.1", "url": "https://www.ensembl.org/id/ENSGALT00010003878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002182.1", "url": "https://www.ensembl.org/id/ENSGALP00010002182.1" } ] } }, { "isoform_ac": "A0A8V0XCJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38/entry#A0A8V0XCJ1-1", "sequence": { "sequence": "MPLSRAHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQSQLKDMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIINTNDAVVPPPEPNSDLQGVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKISGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMSRAGGRTLAALQPEQRAEIIYRLADLLTDQREEILLANKKDLEEAENKGRLALPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRIIRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVSALAIASGNGLLLKGGKEAAYSNQILHHLTQEALSIHGVKDAVNTREEVEDLCRLDKLIDLIIPRGSSQLVRNIQKAAKGIPVMGHSEGICHVYVDTDASVEKVTRIIRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSVQEAVEHIHKYGSSHTDVIITENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGIEGLLTTKWLLRGDNHVVSDFSEHGSMKYLHENLPLPHRNTS", "length": 742, "header": "tr|A0A8V0XCJ1-1|A0A8V0XCJ1_CHICK Computationally mapped isoform of Delta-1-pyrroline-5-carboxylate synthase OS=Gallus gallus OX=9031 GN=ALDH18A1 PE=1 SV=1 CANONICAL=A0A1D5PL38-1" }, "locus": { "chromosome": "6", "start_pos": 36155368, "end_pos": 36126120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003882.1", "url": "https://www.ensembl.org/id/ENSGALT00010003882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002185.1", "url": "https://www.ensembl.org/id/ENSGALP00010002185.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-8964539", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964539", "resource": "Reactome", "description": "Glutamate and glutamine metabolism" }, { "id": "R-GGA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AAN3-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "Aldh18a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRHVQRSGLQPFSQRLLPWVQSIALPRSHRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAEGRLAGPLLKRLSLSTSKLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAMHSNRILHLLTQEALSIHGVKEAIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFSEHGRLKYLHENLPVPQRHFS", "length": 791 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B4R7-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "aldh18a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQRMFSCSRLLARPNALQTFRRAASQGKNPSSSPFHTVHAVRQWSNVPFFTVPLARAHGKSFAHRSELRQAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVAMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKDMSLPVLEARACAAAGQSGLMALYEAMFTQYSTCTAQILVTNLDFHDEQKRRNLNSTLYELLRMNIVPIINTNDAVVPPPEPNSDLQGVNVISIKDNDSLAARLAVEMRADLLIALSDVEGLYDSPPGSDDAKLLDTFYPGDQQSITYGTKSRVGIGGMEAKVKAALWALQGGTSVVIANGTHPKVTGHVITDIVEGKKVGTFFSEVKPAGPTVEQQTEMARSAGRTLASLEPEQRSDIICALADLLTERKEEILSANKKDMENAVNTGRLSPAMLKRLSLSSSKLNSLSIGLRQIAVSSQDSVGRVLRRTRVANNLELEQITVPIGVLLVIFESRPDCLPQVSALAIASGNALLLKGGKEAANTNRILHELAQEALSIHGVKDAIQLVSTREEVEDLCRLEKMIDLIIPRGSSQLVRDIQRAAKGIPVLGHSEGICHVYVDHEASIDKAIKIIRDSKCDYPAACNAMETLLVHRDLLRTPVFDQIIDMLRTEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLECCIEVVDSMQEAIDHIHKYGSSHTDVIVTENENTAEQFLQQLDSACVFWNASSRFADGYRFGLGAEVGISTARIHARGPVGLEGLLTTKWVLRGEGHTVADFSEHGSMTYLHENLPVAQLLPGYRTTS", "length": 805 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SC47-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "ALDH18A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSQVCRSGFQSFTQHLLPWVQSTTLSRSGHIQPSAIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIIYHLADLLTDQRDEILLANKKDMEEAEGRLAAPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEASHSNRILHLLTQEALSIHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKATRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGEDHVVSDFSEHGSLKYLHENLPVPQRNTN", "length": 795 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HXX8-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "Aldh18a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRYMHRSGFQPFNQRLLPWVQSIAVPRSHGVQPSAVRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLAPEQRAEIIHHLADLLTDQREEILLANKKDLEEAEGRLATPLMKRLSLSTSKLNSLAIGLRQIAASSQDSVGRILRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHHLTQEALSIHGVKDAIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRIEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFSEHGSLKYLHENLPVPQRNFS", "length": 795 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P54886-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "ALDH18A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSQVYRCGFQPFNQHLLPWVKCTTVFRSHCIQPSVIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLANKKDLEEAEGRLAAPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDNVQDAIDHIHKYGSSHTDVIVTEDENTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGKDHVVSDFSEHGSLKYLHENLPIPQRNTN", "length": 795 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54887-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase A", "gene_name": "P5CSA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEELDRSRAFARDVKRIVVKVGTAVVTGKGGRLALGRLGALCEQLAELNSDGFEVILVSSGAVGLGRQRLRYRQLVNSSFADLQKPQTELDGKACAGVGQSSLMAYYETMFDQLDVTAAQLLVNDSSFRDKDFRKQLNETVKSMLDLRVIPIFNENDAISTRRAPYQDSSGIFWDNDSLAALLALELKADLLILLSDVEGLYTGPPSDPNSKLIHTFVKEKHQDEITFGDKSRLGRGGMTAKVKAAVNAAYAGIPVIITSGYSAENIDKVLRGLRVGTLFHQDARLWAPITDSNARDMAVAARESSRKLQALSSEDRKKILLDIADALEANVTTIKAENELDVASAQEAGLEESMVARLVMTPGKISSLAASVRKLADMEDPIGRVLKKTEVADGLVLEKTSSPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEARRSNAILHKVITDAIPETVGGKLIGLVTSREEIPDLLKLDDVIDLVIPRGSNKLVTQIKNTTKIPVLGHADGICHVYVDKACDTDMAKRIVSDAKLDYPAACNAMETLLVHKDLEQNAVLNELIFALQSNGVTLYGGPRASKILNIPEARSFNHEYCAKACTVEVVEDVYGAIDHIHRHGSAHTDCIVTEDHEVAELFLRQVDSAAVFHNASTRFSDGFRFGLGAEVGVSTGRIHARGPVGVEGLLTTRWIMRGKGQVVDGDNGIVYTHQDIPIQA", "length": 717 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q2KJH7-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "ALDH18A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSQVCRSGSQSFTQRLLPWVQPTILSRSRRVQPSAIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLANKKDLEEAEGRLATPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEASHSNRILHLLTQEALSIHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDSVQDAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFSEHGSLKYLHENLPIPQRNTN", "length": 795 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VNW6-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "P5CS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLQNSFKLAQSLRNGFYRNAWRAFSSHGPRQPLVSPERRLEKAHPTFTERSQLKYARRLVVKLGSAVITREDNHGLALGRLASIVEQVAECHLEGREVMMVTSGAVAFGKQKLAQELLMSLSMRETLNPKDSKEFDGATLEPRAAAAVGQSGLMSLYDAMFAQYGVKIAQVLVTKPDFYNEETRNNLFCTLSELISLNIVPIINTNDAVSPPMFIRDDEPAGGARRGIPIKDNDSLSAMLAAEVQADLLILMSDVDGIYNKPPWEDGAKLMHTYTSDDSNSIEFGKKSKVGTGGMDSKVKAATWALDRGVSVVICNGMQEKAIKTIIGGRKVGTFFTEATESANAVPVEVMAENARTGSRQMQALTPAQRASAVNTLADLLVSREKFILDANAKDLAEAQKSGLAKPLLSRLSLNPAKLKNLSVGLKQIAEDSHKNVGRVLRRTRLADQLELKQVTVPIGVLLVIFESRPDSLPQVAALAMASANGLLLKGGKEAAHSNKALMELVKEALATVGAEHAVSLVSTREEISDLLSMENHIDLIIPRGSSDLVRSIQQQSLHIPVLGHAEGVCHVYIDRDADLEKALRIARDAKCDYPAACNAMETLLIHEDLMSGAIFGDVCNMLKREGVKIYAGPRLNQQLTFGPPAAKSLKHEYGALECCIEVVPSLDEAINHIHTYGSSHTDVIVTENDAAARQFLGSVDSACVFHNASSRFADGFRFGLGAEVGISTARIHARGPVGVEGLLTTKWILEGQDHAAADFAEGGGRTWLHETLPLD", "length": 776 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z110-1", "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "Aldh18a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRHMHRSGVQPFRQRLLPWVQSIAVPRSNRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAEGRLASPLLKRLSLSTSKLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKEAIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFSEHGSLKYLHENLPVPQRNFS", "length": 795 }, "evidence": [ { "id": "A0A1D5PL38", "url": "https://omabrowser.org/oma/group/A0A1D5PL38/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "glutamate 5-kinase activity", "id": "GO:0004349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004349", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "glutamate-5-semialdehyde dehydrogenase activity", "id": "GO:0004350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004350", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "L-proline biosynthetic process", "id": "GO:0055129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055129", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "citrulline biosynthetic process", "id": "GO:0019240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019240", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "glutamate metabolic process", "id": "GO:0006536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006536", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" }, { "name": "ornithine biosynthetic process", "id": "GO:0006592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006592", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14877", "name": "", "equation": "L-glutamate + ATP = L-glutamyl 5-phosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PL38-1" ], "evidence": [ { "id": "14877", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14877" } ] }, { "id": "19541", "name": "", "equation": "L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)", "summary": "", "cellular_location": "", 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