{
    "uniprot_canonical_ac": "A0A1D5PI40-1",
    "uniprot_ac": "A0A1D5PI40",
    "uniprot_id": "A0A1D5PI40_CHICK",
    "mass": {
        "chemical_mass": 26386.0,
        "monoisotopic_mass": 26386.0
    },
    "refseq": {
        "ac": "XP_001232151",
        "name": "homeobox protein EMX1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232151"
    },
    "gene_names": [
        {
            "name": "EMX1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40",
            "id": "A0A1D5PI40"
        },
        {
            "name": "EMX1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232151",
            "id": "XP_001232151"
        }
    ],
    "protein_names": [
        {
            "name": "Empty spiracles homeobox 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40/entry#names_and_taxonomy",
            "id": "A0A1D5PI40"
        },
        {
            "name": "homeobox protein EMX1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232151",
            "id": "XP_001232151"
        }
    ],
    "function": [
        {
            "annotation": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001232151.2. COMPLETENESS: full length.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "XP_001232151",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232151"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Gallus gallus",
            "taxid": 9031,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A1D5PI40",
                    "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                }
            ],
            "common_name": "Chicken",
            "glygen_name": "Chicken",
            "reference_species": "Gallus gallus [9031]"
        }
    ],
    "gene": [
        {
            "name": "EMX1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40",
            "locus": {
                "chromosome": "4",
                "start_pos": 89440129,
                "end_pos": 89448956,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSGALG00010018362",
                        "url": "https://www.ensembl.org/id/ENSGALG00010018362"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A1D5PI40",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PI40",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSGALG00000030516",
            "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030516",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00086",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "768977",
            "url": "https://www.ncbi.nlm.nih.gov/gene/768977",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000047",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000047",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001356",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR009057",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017970",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020479",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR050877",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR050877",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "gga:768977",
            "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768977",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "SPHPFFG",
            "url": "https://omabrowser.org/oma/group/SPHPFFG/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A1D5PI40",
            "url": "https://www.orthodb.org/?gene=A0A1D5PI40",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A8V0YZE1",
            "url": "https://www.orthodb.org/?gene=A0A8V0YZE1",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24339",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24339",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24339:SF26",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24339:SF26",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00046",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_001232151",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232151",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1D5PI40",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1D5PI40-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0YZE1",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0YZE1-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MFQPSAKRCFTIESLVAKDTPLSPEEPLRPSALNYPPPAASDAFPGGFQGAAAGRALYGGTELVFPEAVGHPALPVAPHQLGASPLPHPHSFFGPQHRDPLNFYPWVLRNRFFGHRFQGSEVSQESLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLASSLSLSETQVKVWFQNRRTKYKRQKLEEEGPDSEQKKKGSHHINRWRLATKQSSGEDIDVTSND",
        "length": 235,
        "header": "tr|A0A1D5PI40-1|A0A1D5PI40_CHICK Isoform 1 of Empty spiracles homeobox 1  OS=Gallus gallus OX=9031 GN=EMX1 PE=3 SV=1 CANONICAL=A0A1D5PI40-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A1D5PI40-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40/entry#A0A1D5PI40-1",
            "sequence": {
                "sequence": "MFQPSAKRCFTIESLVAKDTPLSPEEPLRPSALNYPPPAASDAFPGGFQGAAAGRALYGGTELVFPEAVGHPALPVAPHQLGASPLPHPHSFFGPQHRDPLNFYPWVLRNRFFGHRFQGSEVSQESLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLASSLSLSETQVKVWFQNRRTKYKRQKLEEEGPDSEQKKKGSHHINRWRLATKQSSGEDIDVTSND",
                "length": 235,
                "header": "tr|A0A1D5PI40-1|A0A1D5PI40_CHICK Isoform 1 of Empty spiracles homeobox 1  OS=Gallus gallus OX=9031 GN=EMX1 PE=3 SV=1 CANONICAL=A0A1D5PI40-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 89448247,
                "end_pos": 89440671,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010044332.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010044332.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010026378.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010026378.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8V0YZE1-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40/entry#A0A8V0YZE1-1",
            "sequence": {
                "sequence": "FVSYFLRKNCFSYFLTLSPHSSFFLFLPFLSSFPSPYPLPCFFPFSSSLSFSSFLFPLSFSFSVFLFPLFFSFFPYLFPFLSFSFSSPLLSSPLLSSPLLSSPLLSSPLLSSPLLSSPFVPFRLLSFPLLSFSFFFFLFLSLLFLPLHSLEQPCRQTRSVPPTELSHIITRLLPGSEVSQESLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLASSLSLSETQVKVWFQNRRTKYKRQKLEEEGPDSEQKKKGSHHINRWRLATKQSSGEDIDVTSND",
                "length": 291,
                "header": "tr|A0A8V0YZE1-1|A0A1D5PI40_CHICK Computationally mapped isoform of Empty spiracles homeobox 1  OS=Gallus gallus OX=9031 GN=EMX1 PE=3 SV=1 CANONICAL=A0A1D5PI40-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 89447500,
                "end_pos": 89440671,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010044330.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010044330.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010026376.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010026376.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "gga:768977",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768977",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZV90-1",
            "protein_name": "Empty spiracles homeobox 1",
            "gene_name": "Emx1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MCQAWCTPRTAAAPGHRAFPRAPLPHSSSAAATMFQPATKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEPLRPTALNYPHPSAAETAFVSGFPAAAAAGASRSLYGGPELVFPEAMNHPALTVHPAHQLGSSSLQPPHSFFSAQHRDPLHFYPWVLRNRFFGHRFQASEVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND",
                "length": 290
            },
            "evidence": [
                {
                    "id": "A0A1D5PI40",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PI40/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "E1B7Q1-1",
            "protein_name": "Empty spiracles homeobox 1",
            "gene_name": "EMX1",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "MCLAGCTPRTAAAPGHGALPRARVPRSALAAATMFQPTAKRGFTIESLVAKDGGTGGGTGGGGAGSHPLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAGAGRSLYGGPELVFPEAMNHHALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND",
                "length": 288
            },
            "evidence": [
                {
                    "id": "A0A1D5PI40",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PI40/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "F1SLF1-1",
            "protein_name": "Empty spiracles homeobox 1",
            "gene_name": "EMX1",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "MCLAGCTPRTAAAPGRGALPRARLPRSALAAATMFQPTAKRGFTIESLVAKDGGTGGGTGGAGAGSHPLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAGAGRSLYSGPELVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND",
                "length": 288
            },
            "evidence": [
                {
                    "id": "A0A1D5PI40",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PI40/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "Q04741-1",
            "protein_name": "Homeobox protein EMX1",
            "gene_name": "EMX1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MCLAGCTPRKAAAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND",
                "length": 290
            },
            "evidence": [
                {
                    "id": "A0A1D5PI40",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PI40/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q04742-1",
            "protein_name": "Homeobox protein EMX1",
            "gene_name": "Emx1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MFQPAAKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEPLRPTALNYPHPSAAETAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGSSSLQPPHSFFSAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND",
                "length": 257
            },
            "evidence": [
                {
                    "id": "A0A1D5PI40",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PI40/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q804S6-1",
            "protein_name": "Homeobox protein EMX1",
            "gene_name": "emx1",
            "tax_id": 7955,
            "organism": "Danio rerio",
            "sequence": {
                "sequence": "MFSATGKRCFTIESLVAKESPITLEDPIRPTALSYSAPADSFLNGYQSPAGRALYPNPELVFSETVNHAPLSMHPHQLGSAPLQHPHFFGTQHREPLNFYPWVLRNRFFGHRFQGNDVSQDTLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLANSLSLSETQVKVWFQNRRTKYKRQKLEEEGPECTQKKKGNHHINRWRIATKQTGSEDIDVMSDA",
                "length": 231
            },
            "evidence": [
                {
                    "id": "A0A1D5PI40",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PI40/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Zebrafish",
            "common_name": "Zebrafish"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleolus",
                        "id": "GO:0005730",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromosome",
                        "id": "GO:0005694",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 14,
                "go_terms": [
                    {
                        "name": "regulation of transcription by RNA polymerase II",
                        "id": "GO:0006357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "central nervous system development",
                        "id": "GO:0007417",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "brain development",
                        "id": "GO:0007420",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "post-embryonic development",
                        "id": "GO:0009791",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neuron differentiation",
                        "id": "GO:0030182",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neuroepithelial cell differentiation",
                        "id": "GO:0060563",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060563",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1D5PI40",
                                "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI40"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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