{ "uniprot_canonical_ac": "A0A1D5PDQ9-1", "uniprot_ac": "A0A1D5PDQ9", "uniprot_id": "A0A1D5PDQ9_CHICK", "mass": { "chemical_mass": 36261.0, "monoisotopic_mass": 36261.0 }, "refseq": { "ac": "XP_004943671", "name": "dual oxidase maturation factor 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671" }, "gene_names": [ { "name": "DUOXA1L", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9", "id": "A0A1D5PDQ9" }, { "name": "DUOXA1L", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671", "id": "XP_004943671" } ], "protein_names": [ { "name": "Dual oxidase maturation factor 2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9/entry#names_and_taxonomy", "id": "A0A1D5PDQ9" }, { "name": "dual oxidase maturation factor 2 isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671", "id": "XP_004943671" } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DUOXA1L", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9", "locus": {} } ], "crossref": [ { "id": "A0A1D5PDQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "427483", "url": "https://www.ncbi.nlm.nih.gov/gene/427483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427483", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHINITY", "url": "https://omabrowser.org/oma/group/MHINITY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PDQ9", "url": "https://www.orthodb.org/?gene=A0A1D5PDQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31158:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31158:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10204", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_004943671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLFDGIYPFYLQQRKSFVFDVSTIIVVIVFLMLASTFLLIIPGIRGRVRLYWMVRALFSLMVGVVIVVVQFTGDWESGWVTANTSYKSFSCAVVNVDIGLHVGLAGVNITLVGNPVNQVNETINYNEHFAWSFDADYDHSYGEGLEKGLPSPILYVAEKFTTQSPCNVHRQYRISSHYASASLWVAFCTWLISNMLFSTPVLVYGGYMILFTGAFMIFSLLSFSTVRNSLVCPIQFGTTSLWISYGGSFWLTLAVGLLCFVAGITVVALHYFNPELLKTFFDLHENKAEDYREMTEVYVNLQFMNSTLSPPQPSKLTPNDI", "length": 322, "header": "tr|A0A1D5PDQ9-1|A0A1D5PDQ9_CHICK Isoform 1 of Dual oxidase maturation factor 2 OS=Gallus gallus OX=9031 GN=DUOXA1L PE=3 SV=1 CANONICAL=A0A1D5PDQ9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9/entry#A0A1D5PDQ9-1", "sequence": { "sequence": "MTLFDGIYPFYLQQRKSFVFDVSTIIVVIVFLMLASTFLLIIPGIRGRVRLYWMVRALFSLMVGVVIVVVQFTGDWESGWVTANTSYKSFSCAVVNVDIGLHVGLAGVNITLVGNPVNQVNETINYNEHFAWSFDADYDHSYGEGLEKGLPSPILYVAEKFTTQSPCNVHRQYRISSHYASASLWVAFCTWLISNMLFSTPVLVYGGYMILFTGAFMIFSLLSFSTVRNSLVCPIQFGTTSLWISYGGSFWLTLAVGLLCFVAGITVVALHYFNPELLKTFFDLHENKAEDYREMTEVYVNLQFMNSTLSPPQPSKLTPNDI", "length": 322, "header": "tr|A0A1D5PDQ9-1|A0A1D5PDQ9_CHICK Isoform 1 of Dual oxidase maturation factor 2 OS=Gallus gallus OX=9031 GN=DUOXA1L PE=3 SV=1 CANONICAL=A0A1D5PDQ9-1" }, "locus": { "chromosome": "10", "start_pos": 1069284, "end_pos": 1064337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054426.1", "url": "https://www.ensembl.org/id/ENSGALT00010054426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032875.1", "url": "https://www.ensembl.org/id/ENSGALP00010032875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427483", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RUR8-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "DUOXA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLWNGVLPFYPQPRHAAGLSVPLLIVILVFLVLAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAAHFSAEWSVGSVSTKTSYKAFSVERVRAHVGLHVGLEGVNITLTGNPVQQLNETIDYNEQFIWRFGQNYAGAYAEALERGLPNPVLYLAEKFTPSSPCGVYRQYRLAGHYASATLWVAFCFWLLSNMLLSMPVPHYGGLTLLITGAFALFSVFAFASISSVPLCQLRVGSSELTTHYGAAFWITLATGVLCLLLGAAVLSLHYARPSALRLFLEGSVNDLESPTKGSSPLILSNPLHKQFKTSDLTISTNL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEJ5-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "Duoxa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAWDGVLPFYPQPRHAAGFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSTSRVQVHVGLHVGLEGVNITLRGTPMQQLNETIDYNEQFTWRLNEDYTKEYVQALEKGLPDPVLYLAEKFTPNSPCGLYHQYHYAGHYAGATLWVAFCFWIIANALLSMPAPLYGGLALLITGAFTLFSVFAFASISSVPLCHFRLGSAALTPHYGASFWVTLATGILSLLLGGLVVILHYTRPSVLRALLDQNVKDCSNQADGNSHFILDNPQHRQSKTPDLNVTTLL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H0S2-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "Duoxa2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTAWDGVMPFYPQSRHAAGFSVPLLIVIVVFLCLAASFLFILPGIRGHSRWFWLVRVFLSLFIGAEIVAVHFSGDWFVGAVWTNTSYKAFSTARVQVHVGLHVGLVGVNITLKGTPVQQLNETIDYNERFTWRLDEDYTKEYVDALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYAAATLWVAFCFWIIANALLSMPAPLYGGLALLTTSAFTLFAVFAFASVSSVPLCPFRLGSATLTPHYGASFWVTLATGILSLLLGAVVVILHYTKPSALRTFLDQSDKDCRGQAKGNSPLIFDNPQRKQFATPDLNITTVL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1HG44-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "DUOXA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLWNGVLPFYPQPRHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLNETIDYNEQFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYASATLWVAFCFWLLSNVLLSTPAPLYGGLALLTTGAFALFGVFALASISSVPLCPLRLGSSALTTQYGAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAKDCSQERGGSPLILGDPLHKQAALPDLKCITTNL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D311-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "Duoxa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAWDGVLPFYPQPRHAASFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSPSRVQVHVGLHVGLAGVNITLRGTPRQQLNETIDYNERFTWRLNEDYTKEYVHALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYAAATLWVAFCFWIIANALLSMPAPLYGGLALLTTGAFTLFGVFAFASISSVPLCHFRLGSAVLTPYYGASFWLTLATGILSLLLGGAVVILHYTRPSALRSFLDLSVKDCSNQAKGNSPLTLNNPQHEQLKSPDLNITTLL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJQ7-1", "protein_name": "RE74613p", "gene_name": "mol", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKGWFDAFRDDGGPTLYSFSNRTPVTGDVSIVAVSVLFATFYVAFLVIFPGVRKQKFTTFSTVTLSLFVGLVILITRLGSAWHVAHATIIAPYKAFSREKLPARIGTHIGLMHVNVTLTAIPIGNWTPPDIDYNERFTWEGANDMSANYRHALQRGLPFPILTVAEYFSLGREGFSWGGQYRAAGYFASIMLWASLASWLLMNLLLIAVPRYGAYMKALTGALLVCTTVGYHCLLPKRPLSIHLEGGRLEFHFGWCYWLVLVAGILCFIAGVLISIIDLVWPHTFSTVLEVYYGTPYDRHVILEESSDVRYRKPRNSRSLEDPPGLGSRILRRLSSKARDLQPGTAPRRDSPAGVSSSGGVENKGFQSDAPKSPWRYPFRRSQQMAQQQHSHPLHQHPLQQHHQHHQHHHQQQLQFVGGPVVQHPMHHMQRTMSQDSGSSIASAAVQISPLHKHALARMLPNPPVERIRDMDHW", "length": 474 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PDQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PDQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDQ9" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 84, "end_pos": 86 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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