{ "uniprot_canonical_ac": "A0A1B0GSG7-1", "uniprot_ac": "A0A1B0GSG7", "uniprot_id": "A0A1B0GSG7_MOUSE", "mass": { "chemical_mass": 109837.0, "monoisotopic_mass": 109837.0 }, "refseq": {}, "gene_names": [ { "name": "Kif19b", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7", "id": "A0A1B0GSG7" }, { "name": "Gm4869", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7", "id": "A0A1B0GSG7" } ], "protein_names": [ { "name": "Kinesin-like protein", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7/entry#names_and_taxonomy", "id": "A0A1B0GSG7" } ], "function": [ { "annotation": "Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips.", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7#function" }, { "database": "UniProtKB", "id": "ARBA00055376", "url": "https://www.uniprot.org/uniprotkb/ARBA00055376#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Kif19b", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7", "locus": { "chromosome": "5", "start_pos": 140480826, "end_pos": 140431400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000106350", "url": "https://www.ensembl.org/id/ENSMUSG00000106350" } ] } } ], "crossref": [ { "id": "MGI:3646257", "url": "https://alliancegenome.org/gene/MGI:3646257", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A1B0GSG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1B0GSG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSMUSG00000106350", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000106350", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01370", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01370", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "3646257", "url": "http://www.informatics.jax.org/marker/MGI:3646257", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "A0A1B0GSG7", "url": "https://oglcnac.org/atlas/detail/A0A1B0GSG7", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "FRENDTQ", "url": "https://omabrowser.org/oma/group/FRENDTQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1B0GSG7", "url": "https://www.orthodb.org/?gene=A0A1B0GSG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1B0GSG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSQQTTDHSPAQGSPTLREMEPKDQQLMLRVLVLPCPQVALRIRPLNSTELEEGATVIAHKVGDQVVVLMDPGEDPEDTLRAHRSRERTFIFDTVFDQHASQETVYCATIQHLVEGVISGYNTTIFAYGPSGAGKTHTMLGVDAEPGIYLQTLTDLFQAIEETQDNMEYSVSMSYLEIYNEVIRDLLNPSSGFLELREDSRGSIQIAGITEVSTSNAQEIMQLLTKGNRQRTQEPTATNKTSSRSHAVLQVTVHQRSRGGDLAEEVRLGRLFMVDLAGSERAAQTQNRGKRMKEGAHINRSLLALGNCINALSEKGGSRAQYVNFRDSKLTRLLKDALGGNSRTVMIAHISPASTSFEESRTTLLYAYRAKNIKTRVKRNLLNVSYRIAQYTDVISDLRREIGHLKSKIEKQDKEKKSDPGVLDIQVTIPHDAEEDSRLQMNRIRAQLIGAFKEQMEMRRSLVELENTNIELHIDMSRHLLTIADWEREKTHQHVDVDSGERDKEPVDADGEEVGASEPPEVALAREEVNLLLAEQQKTAALKAGLEQRLAHAKQKASQMEKLLPRQVTSEEQREVLQLLCRAHELEVENTELQADNLFRKNLLCQKDFVIQRYHQHRLLCEQVIQGQRQLMQDNGISAPEPLEQQYRLYSRELGEGTLDRLLLQLSVMSSSLQDGPIMNVSPPPTEESSGEPLGDRRDLPWGATFELPQMLLERDSDGNRSSKSTPLRRLGKQDSLLPPPALRILLTPPMLEKPNAPGAKSLISRLQPTAALELRTQQPAGEMSPLLSAQALKEMALGTKSIALIAASRRCKVYDREGGCLDSRDPSPADWRWPHASPSRDRSLDRKAGRKRSPSFTWSLQQTLEKHQPSVDHPSESQLSPALLQPPKPAGKGLFPAVPVASKTKPSLSAHTDENTLQVPEVSFTFPSAMWQSNAAAPSRPPLLPRDIRGSTDSRGRRQSPLPPNNPSKLQGGSAKRPRRPK", "length": 984, "header": "tr|A0A1B0GSG7-1|A0A1B0GSG7_MOUSE Isoform 1 of Kinesin-like protein OS=Mus musculus OX=10090 GN=Kif19b PE=3 SV=1 CANONICAL=A0A1B0GSG7-1" }, "isoforms": [ { "isoform_ac": "A0A1B0GSG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7/entry#A0A1B0GSG7-1", "sequence": { "sequence": "MPSQQTTDHSPAQGSPTLREMEPKDQQLMLRVLVLPCPQVALRIRPLNSTELEEGATVIAHKVGDQVVVLMDPGEDPEDTLRAHRSRERTFIFDTVFDQHASQETVYCATIQHLVEGVISGYNTTIFAYGPSGAGKTHTMLGVDAEPGIYLQTLTDLFQAIEETQDNMEYSVSMSYLEIYNEVIRDLLNPSSGFLELREDSRGSIQIAGITEVSTSNAQEIMQLLTKGNRQRTQEPTATNKTSSRSHAVLQVTVHQRSRGGDLAEEVRLGRLFMVDLAGSERAAQTQNRGKRMKEGAHINRSLLALGNCINALSEKGGSRAQYVNFRDSKLTRLLKDALGGNSRTVMIAHISPASTSFEESRTTLLYAYRAKNIKTRVKRNLLNVSYRIAQYTDVISDLRREIGHLKSKIEKQDKEKKSDPGVLDIQVTIPHDAEEDSRLQMNRIRAQLIGAFKEQMEMRRSLVELENTNIELHIDMSRHLLTIADWEREKTHQHVDVDSGERDKEPVDADGEEVGASEPPEVALAREEVNLLLAEQQKTAALKAGLEQRLAHAKQKASQMEKLLPRQVTSEEQREVLQLLCRAHELEVENTELQADNLFRKNLLCQKDFVIQRYHQHRLLCEQVIQGQRQLMQDNGISAPEPLEQQYRLYSRELGEGTLDRLLLQLSVMSSSLQDGPIMNVSPPPTEESSGEPLGDRRDLPWGATFELPQMLLERDSDGNRSSKSTPLRRLGKQDSLLPPPALRILLTPPMLEKPNAPGAKSLISRLQPTAALELRTQQPAGEMSPLLSAQALKEMALGTKSIALIAASRRCKVYDREGGCLDSRDPSPADWRWPHASPSRDRSLDRKAGRKRSPSFTWSLQQTLEKHQPSVDHPSESQLSPALLQPPKPAGKGLFPAVPVASKTKPSLSAHTDENTLQVPEVSFTFPSAMWQSNAAAPSRPPLLPRDIRGSTDSRGRRQSPLPPNNPSKLQGGSAKRPRRPK", "length": 984, "header": "tr|A0A1B0GSG7-1|A0A1B0GSG7_MOUSE Isoform 1 of Kinesin-like protein OS=Mus musculus OX=10090 GN=Kif19b PE=3 SV=1 CANONICAL=A0A1B0GSG7-1" }, "locus": { "chromosome": "5", "start_pos": 140480823, "end_pos": 140431400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000197549.3", "url": "https://www.ensembl.org/id/ENSMUST00000197549.3" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000147930.2", "url": "https://www.ensembl.org/id/ENSMUSP00000147930.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 723, "start_aa": "Ser", "end_pos": 723, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser723", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "A0A1B0GSG7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A1B0GSG7" }, { "id": "A0A1B0GSG7", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A0A1B0GSG7" } ], "filter_code": "00000000000000010000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxx.xxxxx.xxxxx" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 726, "start_aa": "Ser", "end_pos": 726, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser726", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "A0A1B0GSG7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A1B0GSG7" }, { "id": "A0A1B0GSG7", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A0A1B0GSG7" } ], "filter_code": "00000000000000010000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxx.xxxxx.xxxxx" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Modernizing reference genome assemblies.", "journal": "PLoS Biol.", "date": "2011", "authors": "Church Deanna M, Schneider Valerie A, Graves Tina, Auger Katherine, Cunningham Fiona, Bouk Nathan, Chen Hsiu-Chuan, Agarwala Richa, McLaren William M, Ritchie Graham R S, Albracht Derek, Kremitzki Milinn, Rock Susan, Kotkiewicz Holland, Kremitzki Colin, Wollam Aye, Trani Lee, Fulton Lucinda, Fulton Robert, Matthews Lucy, Whitehead Siobhan, Chow Will, Torrance James, Dunn Matthew, Harden Glenn, Threadgold Glen, Wood Jonathan, Collins Joanna, Heath Paul, Griffiths Guy, Pelan Sarah, Grafham Darren, Eichler Evan E, Weinstock George, Mardis Elaine R, Wilson Richard K, Howe Kerstin, Flicek Paul, Hubbard Tim", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "reference": [ { "type": "PubMed", "id": "21750661", "url": "https://glygen.org/publication/PubMed/21750661" } ] }, { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A1B0GSG7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A1B0GSG7" }, { "database": "O-GlcNAc Atlas", "id": "A0A1B0GSG7", "url": "https://oglcnac.org/atlas/detail/A0A1B0GSG7" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZY72-1", "protein_name": "Kinesin-like protein", "gene_name": "Kif19b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSQQTTDPSPARGSPTLREMEPKDQQLMLRVLVLPVPCPQVALRIRPLNSTELEEGATVIAHKVGDQVVVLMDPGEDPEDTLRAHRSRERTFIFDTVFDQQASQETVYRVTIQHLVEGVISGYNATVFAYGPSGAGKTHTMLGMDAEPGIYLQTLTDLFQAIEETQDNMEYSVSMSYLEIYNEVIRDLLNPSSGFLELREDSRGSIQIAGITEVSTSNAQEIMQLLTKGNRQRTQEPTATNKTSSRSHAVLQVTVHQRSRGGDLAEEVRLGRLFMVDLAGSERAAQTQNRGKRMKEGAHINRSLLALGNCINALSEKGGSRAQYVNFRDSKLTRLLKDALGGNSRTVMIAHISPASTSFEESRTTLLYAYRAKNIKTRVKRNLLNVSYRIAQYTDVISDLRREIEHLKSKIEKQDKEKKSDPSVLDIQVTVPQDAEEDSRLQMNKIRAQLIGAFKEQMEMRRSLVELENTNIELHIDMSRHLLTIADWEKTLHHANMDKSKKDKEPVDADGEEVEASEPPEVALAREEVNLLLAEQQKTAALKAGLEQRLAHAKQKASQMEKLLPRQVTSEDQREVLQLLCRAHELEVENTELQADNLCRKNLLCQKDFVIQRYHQHRLLCEEVIQGQRQLMQDKGLSVPEPLEQQYRLYSRELGEGTLDRLLLQLSVMSSSLQDGPIMNVSPAPTEETSGEPLGDRRDLPWGATFELPPMLLERDSDGNRSSKSTPLRRLGKQDSLLPPPALRILLTPPMLEKPSALGVKSLVSRLQATAGLELRTPQPAGEMNSPPLSAQALKEMALGTKSIALIAANRRCKVYDREGGCLDSRDPSPADWRWPHASPSRDRSLDRKAGRKRSPSFTWSLQQALEKHQPSMEHPSESQLSPAHLQPPKPAGRSFFPAVPVPVASKTKPSLSFHTEENVLQVPEVSFTFPSAMWQSNTASSRPPLLPRDIRGSTDSRGRRQSPLPPNNPSKLQGGSAKRPRRPK", "length": 986 }, "evidence": [ { "id": "MGI:3646257", "url": "https://alliancegenome.org/gene/MGI:3646257#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-134", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-134#orthology", "database": "AGR" }, { "id": "RGD:1598146", "url": "https://alliancegenome.org/gene/RGD:1598146#orthology", "database": "AGR" }, { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" }, { "id": "A0A1B0GSG7", "url": "https://omabrowser.org/oma/group/A0A1B0GSG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1Q799-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "si:dkey-26i13.8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDLPGEWMDHQLTVALRIRPLNEAEIEEGATIVAHKIDNQMVVLMDPCEDSDNVLRAHRSREKTYMFDLAFDYTATQEDVYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTMLGLDSEPGIYIRTLNDLFRAIEDSTEDLDCSVYMSYIEIYNEMIRDLLNPSSGYLELREDGKGEIRIAGITEFSTCNAKEIMALLTKGNKQRTQESTAANKTSSRSHAILQVTVKQKSRVKDINEEVRVGKLFMVDLAGTERASQTQNRGKRMKEGAHINRSLLALANCINALSEKGGKGAQFVNYRDSKLTRLLKDALGGNSRTVMITHISPASSNFEESRNTLVYADKAKNIRTKVKRNLMNVSYHLAQYTRIIADLRSEIERLRAKIDQQSQDQLKGEKADIRNIQAEVQQYSHGEMALLQEQLLSAFREQMEIRRSLMELENCNMELHIDTSRHLLTISDWERDRARARREKDELSGQKKHTDKEEEQESMPEEPQYVTAAREEIGPLLAEQRKTMELKRELEEKLLNMKLKSSKIEELLPKRISNTEQRDILMLLCKVHELELEKTEIQSAVLCKENVLRTKDFIIQRHEQQRTLCDDIIHQQKMLIEDQGLCVPEGLQELYSLYFGELSDGIIDQILNLHTFTTNNLNARQLRLDVISNLEEADKAEQSNVKFSPLDKHPRDSSSSGLDYDSDTNRVFKSLSKIKPRRQHHSSSSQTLMRKVCAVKDSTPICPTESVSPDTLREIVSDTKSISVIAAKRRSRLQAKSNSRMAGMGLAAGLKSSVSMDSLVSTLPDESAEVRRSHQRHGGSSQSKQDPKRTEGRTELPEKQQHKKRSRSFEASKRQVQKPRQNASRYPALESISDNHLVRPALNIIQPLNGGPANPATPPVAKVKIPVSHFTGEVQFQKLEIRGTPPSTIHQKHSDTKRAQAVYKRQRGQGDVCYPSSLLQQAGNYKKSTNENPKQKAMADVNRKNETRQRNKHAVKKSYV", "length": 991 }, "evidence": [ { "id": "MGI:3646257", "url": "https://alliancegenome.org/gene/MGI:3646257#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-134", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-134#orthology", "database": "AGR" }, { "id": "RGD:1598146", "url": "https://alliancegenome.org/gene/RGD:1598146#orthology", "database": "AGR" }, { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B2G5-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "kif19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDTGESKDQQLTVALRIRPLSDAELEEGATIIAHKVDDQMVVLLDPMEDPDDILRAHRSREKTYMFDVAFDYSATQDEVYRYTTKGLIEGLISGYNATVFAYGPTGCGKTYTMLGTDREPGIYVRTLNDLFKAIEETSDDMQYSVSMSYLEIYNEMIRDLLNPSSGFLDLREDSKGEIQVAGITEVSTINAREIMELLMKGNKQRTQEPTAANQTSSRSHAVLQVVVRQQSRCRDILQEVRFARLFMIDLAGSERASQTQNRGQRLKEGAHINRSLLALGNCINALSEKNGNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISPASLAFEDSRNTLTYADRAKSIRTRVKRNLLNVSYHIAQYTSIISDLRSEIQRLKKKIADQASRQINPDRTDIRHVQAEVQAHSSQQSRAEMDQLREQLIDAFRQQMDIRKRLMELDNSNMEIQIDTSKHLLTIADWEQERFRRRKKWQGERRKESFNKDESEKDSDSPESLPDSTETQEVAIARENLVTLMAEQKKIQKQKAGLEQRLAELREKARRLEELLPRRVSSEEQREVLCLLCKVHELEIENAEMQSSALLKDNVIRQKNVVVQRFEQHRHLCHEIIQQQRQFIDDHSLLVPPHLQELYEMYMKEMDEKNLDRVVALDKFTIRTLKVHHEGSLPKITLPSRGRDPLQELDSDQESVRTLASDNRQGRTKLRRHTLPPILPEPDGERVFKSSHKQMKNTVVMTPPPIHINGQGNRELLPSVLDEALRCSHLSHSMSSHLDSSPESSENGTDAPLTPKERQQILRGVQNIAVKAARRRSKVLEIDALRLPPPPSPLDPKKHKSNLSLSEAPPKGPVLRRGRQPSPELRHATSDDNLSSSTGDGPAPNGTWTRPRNRQAVRNAGPREQDFEGRRRKRRSRSFEVTGQALSQAKNTNQRFRPLDSTSDPHLHINGHPPAPLLRPQHRAQAQLTKARPSHNIHQTGSTADVTSSNPPSHLIKRGPQTRQLQPLLYVTTTGTGGQRTRKH", "length": 1015 }, "evidence": [ { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A976-1", "protein_name": "Kinesin-like protein", "gene_name": "Kif19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVSELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRNRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGGNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASTAFEESRNTLTYAGRAKNIRTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKCKIDQQAGRGQARGKLDRGDIRHIQAEVQLHSGQEEQAEMGQLREQLISAFHEQMDVRRRLLELENQAMEVQIDTSRHLLTIASWEHEKSRRALKWREERRKESYTKEDSEKDSDTGDEPDNLEPPEVASARENIAALVGEQKKLRKEKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDSALRHRREAVRRLEQHRSLCDEIIQGQRQIIDDYNLEIPRHLEELYEVYLRELEEGSLERATIMDRVASRALQDSSLPKITPAGTTLTPDSDLESVKTLSSEAQCPQNNTLPPLGTDSDSYHMFKASPRAWQVKSSSVPTPPPIQVGSLVTQEAPPQDSLGSQINSSPDSSENLSEILLSHKERKEILTRTKCISVKAAQRRSRALGTEGRHLLAPATERSSLSLHSLSEADDVRPPGPLACKRPPSPTLQHAISEDNLSSSTGEGPARAVGPRGDGSGPWVRGQKKCLSKKREESLEAKRRKRRSRSFEVTGQGLSRSKTHLLGPRPSEGVSDRRMPACGRPSPGVRHLGKVSLPLAKVKFPPNQNTGSGNPSPLLVPSNQAGVSRRATRGPNLPHGSSTFGKDGRLQHN", "length": 997 }, "evidence": [ { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2TAC6-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "KIF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEPGIYVQTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMGQLREQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRRALKWREEQRKECYAKDDSEKDSDTGDDQPDILEPPEVAAARESIAALVDEQKQLRKQKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDGALRHRHEAVRRLEQHRSLCDEIIQGQRQIIDDYNLAVPQRLEELYEVYLRELEEGSLEQATIMDQVASRALQDSSLPKITPAGTSLTPDSDLESVKTLSSDAQHLQNSALPPLSTESEGHHVFKAGTGAWQAKSSSVPTPPPIQLGSLVTQEAPAQDSLGSWINSSPDSSENLSEIPLSHKERKEILTGTKCIWVKAARRRSRALGTEGRHLLAPATERSSLSLHSLSEGDDARPPGPLACKRPPSPTLQHAASEDNLSSSTGEAPSRAVGHHGDGPRPWLRGQKKSLGKKREESLEAKRRKRRSRSFEVTGQGLSHPKTHLLGPHQAERISDHRMPVCRHPAPGIRHLGKVTLPLAKVKLPPSQNTGPGDSSPLAVPPNPGGGSRRATRGPRLPHGTSTHGKDGCSRHN", "length": 998 }, "evidence": [ { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7KSK2-1", "protein_name": "5.6.1.3", "gene_name": "Kif19A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATSAGASSWSGSSGGSNSSQGRSIATAQPAQEERLVVAVRVRPSMEATERCIEVISGGSLLYDDGGKSRPRQYSYDHVFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTASCDSTDVSSQDIGLMVRAIEDIFSHIESAEAYSCRVSISYLEIYNELIRDLLNPGGPLELREDHRGQRITVAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPLGTKQGRLFLTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLSGGARYVNYRDSKLTRLLKEALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVSELRDEVSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLREQIVLTFKQQMKLRRKLLEAESHLLGLELDAERQHMIISHWQGRIGKLYDAMGDDDIESEGSVALKNAWGELAAIEKETRRYKEIRERTEHELEQCRQKGVKLEDELPERISSDEERELLALLCRVHELEADKVSLQAERLARQAELRRRDLQLLRAERQRRLCEDIISSQRRLIEEGNVDLPDELRELYGLYQQEIHAGVVTPSTSNYERKLPPIYTAGSDSPGSSSSSEWSPASPLPQIDNQMDPVDRVMGPPVNPRLPRLSAATSANVPAGGSRRPSLRVARNPHPHP", "length": 750 }, "evidence": [ { "id": "MGI:3646257", "url": "https://alliancegenome.org/gene/MGI:3646257#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-134", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-134#orthology", "database": "AGR" }, { "id": "RGD:1598146", "url": "https://alliancegenome.org/gene/RGD:1598146#orthology", "database": "AGR" }, { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" }, { "id": "A0A1B0GSG7", "url": "https://omabrowser.org/oma/group/A0A1B0GSG7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q99PT9-1", "protein_name": "Kinesin-like protein KIF19", "gene_name": "Kif19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDSGDSKDQQLMVALRVRPISVAELEEGATLIAHKMDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDHEPGIYVRTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPALGYLELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVAVRQRSRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASTAFEESRNTLTYAGRAKNIRTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKCKIDQQAGRGQARGKLDRGDIRHIQAEVQLHSGQEGPAEMGQLREQLISAFHEQMDVRRRLLELENQAMEVQIDTSRHLLTIAGWEHEKSRRALKWREERRKESYTKEDSEKDSDTGDEPDNLEPPEVASARENIAALVGEQKKLRKEKLALEQRCRELRARGRRLEETLPRRIGSEEQREVLSLLCRVHELEVENTEMQSHALLRDSALRHRREAVRRLEQHRSLCDEIIQGQRQIIDDYNLEVPRHLEELYEVYLRELEEGSLERATIMDRVASRALQDSSLPKITPAGATLTPDSDLESVKTLSSEAQRPQNNTLPPLGTDSESYHVFKASPRAWQVKSSSVPTPPPIQVGSLVTQEAPPQDSLGSQINSSPESSENLSEILLSHKERKEILTRTKCISVKAAQRRSRALGTEGRHLLAPATERSSLSLHSLSEADDARPPGQLACKRPPSPTLQHAISEDNLSSSTGEGPSRAVGPRGDGTGSWVRGQKKCLSKKREESLEAKRRKRRSRSFEVTGQGLSRPKTHLLGPRPSEGLSDRRMPACGRPSPGVRHLGKVSLPLAKVKFPPNQNTGSGNPSPLLVAPNQAGVSRRATRGPSLPHGSSTFGKDGRLQHN", "length": 997 }, "evidence": [ { "id": "FB:FBgn0038205", "url": "https://alliancegenome.org/gene/FB:FBgn0038205#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSG7", "url": "https://www.uniprot.org/uniprotkb/A0A1B0GSG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1B0GSG7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 984, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1B0GSG7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1B0GSG7" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 723, 726 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 721, "end_pos": 723 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "exact_o_linked_glycan_sites", "count": 2 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "exact_o_linked_glycan_sites", "count": 2 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }