{ "uniprot_canonical_ac": "A0A0U2ULT4-1", "uniprot_ac": "A0A0U2ULT4", "uniprot_id": "A0A0U2ULT4_DANRE", "mass": { "chemical_mass": 149399.0, "monoisotopic_mass": 149399.0 }, "refseq": { "ac": "NP_001305000", "name": "adhesion G protein-coupled receptor A2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000" }, "gene_names": [ { "name": "adgra2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4", "id": "A0A0U2ULT4" }, { "name": "adgra2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000", "id": "NP_001305000" }, { "name": "gpr124; si:dkey-208c22.2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000", "id": "NP_001305000" }, { "name": "gpr124", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4", "id": "A0A0U2ULT4" }, { "name": "si:dkey-208c22.2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4", "id": "A0A0U2ULT4" } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor A2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4/entry#names_and_taxonomy", "id": "A0A0U2ULT4" }, { "name": "G-protein coupled receptor 124; probable G-protein coupled receptor 124", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000", "id": "NP_001305000" }, { "name": "G-protein coupled receptor 124", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4/entry#names_and_taxonomy", "id": "A0A0U2ULT4" }, { "name": "adhesion G protein-coupled receptor A2 precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000", "id": "NP_001305000" } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: KT285523.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KT285523.1. On Dec 22, 2015 this sequence version replaced XP_689189.7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001305000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000" } ] }, { "annotation": "The GPI-anchored MMP inhibitor Reck and the adhesion GPCR Gpr124 are integral components of the Wnt7a/Wnt7b-specific signaling complex required for brain angiogenesis and dorsal root ganglia neurogenesis. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001305000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000" }, { "database": "PubMed", "id": "26051822", "url": "https://glygen.org/publication/PubMed/26051822" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "adgra2", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-363", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "560700", "url": "https://www.ncbi.nlm.nih.gov/gene/560700", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560700", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560700", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A0U2ULT4", "url": "https://www.orthodb.org/?gene=A0A0U2ULT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45930", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45930", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45930:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45930:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001305000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0U2ULT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-363", "url": "https://zfin.org/ZDB-GENE-081104-363", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGPCVRIPFWVRVFLLLLLYRIAAGCPELFSSGCSCTEDRSKAHPTPGTRRKVSCGGKELTETPEVSLLPNRTVSLNLSNNRIRMLKNGSFAGLSSLEKLDLRNNLISTIMPGAFLGLTALRKLDLSSNRIGCLTPEMFQGLTNLTKLNISGNIFSSLDPNVFMELHSLKLVNFHSEFLSCDCGLRWVPSFFRSGSARLGDETLCACPRRLQNKPLRLLRESDLSCEGPLELHTLSLLPSQRQVVFKGDRLPFHCTASLVDKITALHWRQNGQPVTSDPTKGIHLEESVQHDCTFITSELILSNVHVEASGEWECVVPTGRGNTSCSVEIVVLENSASFCPEQKVNNNRGEFRWPRTLAGITSYQHCLQLRYPSLTLGGGVEQKKASRNCDRSGRWEEADYSQCLYTNDITRILHTFILMPVNASNAVTLAHQVRSYTLEAAGFTDTVDVLYVAQMMHKFMDYVTELRELSEVLVEMGSNLMQVDDQILARAQREERACSSIVYTLETLAWPQLHSHAQDLSRNSRNIVMEAHLIRPAHFTGISCTVYQRREGAAGSQVHDGADLSLEQQLRFRCTTGTHNTSLNAFHLKNAVALATVSLPATLFPPNAPPDCKLQFVAFRNGRFFPFTSNFTGHSDLARRRGISTPVIYAGLDGCSMWNQSDPIIVSLRHTSPGHDPVAAHWNSQALGHHGSWSLDGCQLIHSDVSISTLRCSVLSNYAVLQEIPDFPGSPSVPVEVLHPVIYTCTAVLLLCLFTIIITYILHHSSIRITRKSWHTLLNTSFHVAMTSAVFAGGITLTGYPIVCQAVGIVLHYSSLSTLLWIGVSARVIYKEALLRTPQQLEGESAVQPTQRPMLRFYLIAGGVPLIICGITAAVNINNYGDNIPYCWLVWQPSFGAFYIPAGLIILVTWIYFLCTVFCLRQRNFQESKDLQCSASDPSNLPESQPALSGSTSLLSTDSGVSPVHAGTTVEDQYSLKVQCLALMATQFVFVGLWCCGAMAVWHVDRERKLFSCLYGGTATGLGIFLVLHYCFKRLDVQAAWLGCCPGYHRSQPMPAYSHPCTVTVGVQSASERGSQLFVACHPPTDPNHYSSSARSSSTQSGTASITVAPCKLTNLLQVSQDNANNASRAPAGTNTNTSTSTENNKPTNNLLPSLLPVQQPQRRKACSRTKGGNTQYHHRGDARSHYRLKALRAGGGGSMGALGPSGTEHSNIYHVHKHASSENGSLRNSHSEGQNGLLTNGRHRGEGLATSPSEGSDGGSSGSRKPFPLLPSVARRAAMQQNAQCRSASKDNLKLAAAAERESKRSSFPLNMSSNVTATASLSTVSAPNGTLKGSVVELDTSGTDQSQGSVGMKSRVWKSETTV", "length": 1367, "header": "tr|A0A0U2ULT4-1|A0A0U2ULT4_DANRE Isoform 1 of Adhesion G protein-coupled receptor A2 OS=Danio rerio OX=7955 GN=adgra2 PE=2 SV=1 CANONICAL=A0A0U2ULT4-1" }, "isoforms": [ { "isoform_ac": "A0A0U2ULT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4/entry#A0A0U2ULT4-1", "sequence": { "sequence": "MSGPCVRIPFWVRVFLLLLLYRIAAGCPELFSSGCSCTEDRSKAHPTPGTRRKVSCGGKELTETPEVSLLPNRTVSLNLSNNRIRMLKNGSFAGLSSLEKLDLRNNLISTIMPGAFLGLTALRKLDLSSNRIGCLTPEMFQGLTNLTKLNISGNIFSSLDPNVFMELHSLKLVNFHSEFLSCDCGLRWVPSFFRSGSARLGDETLCACPRRLQNKPLRLLRESDLSCEGPLELHTLSLLPSQRQVVFKGDRLPFHCTASLVDKITALHWRQNGQPVTSDPTKGIHLEESVQHDCTFITSELILSNVHVEASGEWECVVPTGRGNTSCSVEIVVLENSASFCPEQKVNNNRGEFRWPRTLAGITSYQHCLQLRYPSLTLGGGVEQKKASRNCDRSGRWEEADYSQCLYTNDITRILHTFILMPVNASNAVTLAHQVRSYTLEAAGFTDTVDVLYVAQMMHKFMDYVTELRELSEVLVEMGSNLMQVDDQILARAQREERACSSIVYTLETLAWPQLHSHAQDLSRNSRNIVMEAHLIRPAHFTGISCTVYQRREGAAGSQVHDGADLSLEQQLRFRCTTGTHNTSLNAFHLKNAVALATVSLPATLFPPNAPPDCKLQFVAFRNGRFFPFTSNFTGHSDLARRRGISTPVIYAGLDGCSMWNQSDPIIVSLRHTSPGHDPVAAHWNSQALGHHGSWSLDGCQLIHSDVSISTLRCSVLSNYAVLQEIPDFPGSPSVPVEVLHPVIYTCTAVLLLCLFTIIITYILHHSSIRITRKSWHTLLNTSFHVAMTSAVFAGGITLTGYPIVCQAVGIVLHYSSLSTLLWIGVSARVIYKEALLRTPQQLEGESAVQPTQRPMLRFYLIAGGVPLIICGITAAVNINNYGDNIPYCWLVWQPSFGAFYIPAGLIILVTWIYFLCTVFCLRQRNFQESKDLQCSASDPSNLPESQPALSGSTSLLSTDSGVSPVHAGTTVEDQYSLKVQCLALMATQFVFVGLWCCGAMAVWHVDRERKLFSCLYGGTATGLGIFLVLHYCFKRLDVQAAWLGCCPGYHRSQPMPAYSHPCTVTVGVQSASERGSQLFVACHPPTDPNHYSSSARSSSTQSGTASITVAPCKLTNLLQVSQDNANNASRAPAGTNTNTSTSTENNKPTNNLLPSLLPVQQPQRRKACSRTKGGNTQYHHRGDARSHYRLKALRAGGGGSMGALGPSGTEHSNIYHVHKHASSENGSLRNSHSEGQNGLLTNGRHRGEGLATSPSEGSDGGSSGSRKPFPLLPSVARRAAMQQNAQCRSASKDNLKLAAAAERESKRSSFPLNMSSNVTATASLSTVSAPNGTLKGSVVELDTSGTDQSQGSVGMKSRVWKSETTV", "length": 1367, "header": "tr|A0A0U2ULT4-1|A0A0U2ULT4_DANRE Isoform 1 of Adhesion G protein-coupled receptor A2 OS=Danio rerio OX=7955 GN=adgra2 PE=2 SV=1 CANONICAL=A0A0U2ULT4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 1066, "start_aa": "Thr", "end_pos": 1066, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1066", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] }, { "title": "Modulation of dorsal root ganglion development by ErbB signaling and the scaffold protein Sorbs3.", "journal": "Development", "date": "2013", "authors": "Malmquist Sarah J, Abramsson Alexandra, McGraw Hillary F, Linbo Tor H, Raible David W", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "24004948", "url": "https://glygen.org/publication/PubMed/24004948" } ] }, { "title": "Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish.", "journal": "BMC Genomics", "date": "2015", "authors": "Harty Breanne L, Krishnan Arunkumar, Sanchez Nicholas E, Schi\u00f6th Helgi B, Monk Kelly R", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "25715737", "url": "https://glygen.org/publication/PubMed/25715737" } ] }, { "title": "Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/beta-catenin pathway during brain angiogenesis.", "journal": "Elife", "date": "2015", "authors": "Vanhollebeke Benoit, Stone Oliver A, Bostaille Naguissa, Cho Chris, Zhou Yulian, Maquet Emilie, Gauquier Anne, Cabochette Pauline, Fukuhara Shigetomo, Mochizuki Naoki, Nathans Jeremy, Stainier Didier Yr", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" }, { "database": "RefSeq", "id": "NP_001305000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305000" } ], "reference": [ { "type": "PubMed", "id": "26051822", "url": "https://glygen.org/publication/PubMed/26051822" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders.", "journal": "Science", "date": "2022", "authors": "Martin Maud, Vermeiren Simon, Bostaille Naguissa, Eubelen Marie, Spitzer Daniel, Vermeersch Marjorie, Profaci Caterina P, Pozuelo Elisa, Toussay Xavier, Raman-Nair Joanna, Tebabi Patricia, America Michelle, De Groote Aur\u00e9lie, Sanderson Leslie E, Cabochette Pauline, Germano Raoul F V, Torres David, Boutry S\u00e9bastien, de Kerchove d'Exaerde Alban, Bellefroid Eric J, Phoenix Timothy N, Devraj Kavi, Lacoste Baptiste, Daneman Richard, Liebner Stefan, Vanhollebeke Benoit", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "35175798", "url": "https://glygen.org/publication/PubMed/35175798" } ] }, { "title": "Sulfamethoxazole induces brain capillaries toxicity in zebrafish by up-regulation of VEGF and chemokine signalling.", "journal": "Ecotoxicol. Environ. Saf.", "date": "2022", "authors": "Xu Yuhang, Luo Lingfei, Chen Jingying", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "35561544", "url": "https://glygen.org/publication/PubMed/35561544" } ] }, { "title": "An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates.", "journal": "Cell Rep.", "date": "2022", "authors": "America M, Bostaille N, Eubelen M, Martin M, Stainier DYR, Vanhollebeke B", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "35649360", "url": "https://glygen.org/publication/PubMed/35649360" } ] }, { "title": "Brain endothelial cells acquire blood-brain barrier properties in the absence of Vegf-dependent CNS angiogenesis.", "journal": "Dev. Biol.", "date": "2023", "authors": "Fetsko Audrey R, Sebo Dylan J, Taylor Michael R", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "36502932", "url": "https://glygen.org/publication/PubMed/36502932" } ] }, { "title": "Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries.", "journal": "Elife", "date": "2023", "authors": "Parab Sweta, Card Olivia A, Chen Qiyu, America Michelle, Buck Luke D, Quick Rachael E, Horrigan William F, Levkowitz Gil, Vanhollebeke Benoit, Matsuoka Ryota L", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "reference": [ { "type": "PubMed", "id": "37191285", "url": "https://glygen.org/publication/PubMed/37191285" } ] } ], "pathway": [ { "id": "dre:560700", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560700", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JSU2-1", "protein_name": "Adhesion G protein-coupled receptor A3", "gene_name": "Adgra3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERPPLLLPLALLALLWGGERGAVALPAGCKHDGRARGTGRAAGAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISRIAPGAFWGLSSLKRLDLTNNRIGCLNADVFRGLTNLVRLNLSGNLFTSLSQGTFDYLGSLRSLEFQTEYLLCDCNILWMHRWVKERNITVRDTRCVYPKSLQAQPVTGVKQELLTCGPPLELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHIQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNSHSSGVYPGNTQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTKEEKSKELGDVMVDVASNIMLADERVLWLAQREAKACSRIVQCLQRIATHRLASGAHVYSTYSPNIALEAYVIKAAGFTGMTCSVFQKVAASDRTGLSDYGRRDPDGNLDKQLSFKCNVSSTFSSLALKNTIMEASIQLPSSLFSPKQKREVRATDDSLYKLQLIAFRNGKLFPATGNSTKLADDGKRRTVVTPVILTKIDGVTTDTHHVPVNVTLRRIAHGADAIAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMDLTGSELYTPAASLLHPVVYTTAITLLLCLLAVIISYMYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASVCQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPAPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPSAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPAEEQQRLAANENGEINPQDSMSLSLISTSTLENEHSFQSQLLGASLTLLLYITLWMFGAMAVSLDYPLDLVFSFFFGASCLSFSAFIMVHHCINREDVRLSWIMMCCPGRGSYSVQVNVQPPTSSAANGEAPKCTNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQYHSNALPVSATPQLDNSLTEHSMDNDIKMHVAPLDVQFRANMHPSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSGQSGSPKSRPGSSEGHSRSRRAYLAYRERQCNPPQQDSSDAGSTLPKSGRNVEKPLSTSSKKDAPRKPAAADLESQQKSYGLNLAVQNGPVKSNGQEGPLLATDITGNIRTGLWKHETTV", "length": 1307 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K4I3-1", "protein_name": "Adhesion G protein-coupled receptor A1", "gene_name": "Adgra1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQWDLKTVLSLPQYPGEFLHPVVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTKHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPGADQPPYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFITLVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPETGHRHGMRPGTPPTCDALAASQLQNEHSFKAQLRAAAFTLFLFTATWTFGALAVSQGDFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWSCCPSRGDTSATKPSAHPTLDANGDALGHTACLQDSPCPGKLRGFGHPPASHCKMTNLHAAQGHVSCLSPATPCCAKMHCEQLMEEEAHVHMGEEDAFPHDHHLHDPHLHRCLKGRTKPHYFSRHQAAAAEREYAYHIPSSLDGSPHSSRTESPTSSLEGPMGVHTLACCAQADPFPMVSQPEGGDTSPGLYGCPPRLSPGPAHLEMLRRTQSLPFGSPSQNGLLQGDVREGLPFGTDGTGNIRTGPWKNETTV", "length": 577 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADC7-1", "protein_name": "Adhesion G protein-coupled receptor A2", "gene_name": "Adgra2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPRPALGRPGLPLSTPLARSGPSSRRTVRPLRCRSPRGDGLMGAGGRRMPVRSARLLLLPLLPCLLLLAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNPARRRVVCGGGDLPEPPDPGLLPNGTITLLLSNNKITGLRNGSFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIYSSLQPGVFDELPDLKIVDFGTEFLTCDCRLRWLLPWARNHSLQLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGNDTQIHWYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQGNTSKKVEIVVLETSASYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTAFQRREVGVSGVQPSSPGQDVPLEPEALADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSTLPAALAPPVPPDCTLQLLVFRNGRLFRSHGNTSRPGTAEPSKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGTDPLAAWWNQDGPGGWSSEGCKLRFSQPNVSSLYCQHLGNVAVLMELSAFPREAGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFVGGVTLTNYQMVCQAVGITLHYSSLSSLLWMGVKARVLHKELSWRAPPPEEGEAAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILPITWIYFLCAGLHLRGHVAQNPKQGNSRLSLEPGEDPRGSTRLRSSGVLLSDSGSLLATVSAGVGTPAPPEESDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPSASHAPPRALPTAAEDGSPVLGEGPASLKSSPSGSSGRAPPPPCKLTNLQVAQSQVCEASMVARGDGEPEPTGSRSSLAPRHHNNLHHGRRVHKSRAKGHRAGETGGKSRLKALRAGTSPGAPELLSSESGSLHNSPSDSYPGSSRNSPGDGLPLEGEPMLTPSEGSDTSAAQIPETGRPGQRRSASRDNLKGSGSALERESKRRSYPLNTTSLNGAPKGGKYEDASVTGAEAIAGGCMKTGLWKSETTV", "length": 1378 }, "evidence": [ { "id": "HGNC:17849", "url": "https://alliancegenome.org/gene/HGNC:17849#orthology", "database": "AGR" }, { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" }, { "id": "MGI:1925810", "url": "https://alliancegenome.org/gene/MGI:1925810#orthology", "database": "AGR" }, { "id": "RGD:2323365", "url": "https://alliancegenome.org/gene/RGD:2323365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-363#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KV24-1", "protein_name": "Remoulade", "gene_name": "Remo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPTATATSTAAEGGQAVQVQTHQDTELPQNPETGIATGQGTASSCPRKCSCRSTAENIHSLKIRCDEQQITNWRELDFGEDVTSIVSINASKNSIALITAEDFRNFTELKRLDLSFNLLTELDKDTFGDSLAHLEKLKLAGNAISHIYEGTFDQMPKLKLLDLSGNPLACDCGLIWLIAWSSSREVRLQPPPKCESPGNFRGMPLKKLRVGKDFHCETLLQPLLELIPSQNQVAFEGDELQLKCHAPRVAIGVPRESEDLPTKAYVFWGWSEKIRAKNSTEDIIYQDPTKVFGDVNLETRHSTDSGILQSILRIASLTQNHTGMWDCTLRSQQANLSQAIVLHVVAKGTLYCEARVVHTNKGTYHWPRTMRGETVLQECVEEPSDATQARRASHECGPSGEWLNLDTESCVYVSETTRILEQFAKVNLTLTKGQNALEIARRLHNFTQAQTQLNRIRDPMDLEYIARTLVKYLDQLEQPQQQQEISHLLMDIVSQLLNLPAHLFRAAQSEQGTGQRLLHVVESSAMRLALASTQAEPLPAEMIPWRGSLAQQRNLFVEFFNISLDAFVSLSCVWLEQSPRGFQCNSANDTIPMYEHGDIDAAIQLPYSVIGNSSTTLPATTTIRSLRLMISLHRNGKLLPNLRGSHNESLSSAIIGILAYSSDGEALQFRADNELDPEEDVYQQRVTVMLRAHPYHNPLSAPQPAWWDADEQRWETSVCQQHYQHRTLVMFSCSRTGYYGLLQRSQYLNDFRSEESGARFRHPPAAVYAGCGLLFACCAFNAVTFAVFGRAVRINRVQRHALVNTWLALGALALAFSLGIYQTASQPQCRLLGLLMHYLGLCVLLWVCVSLSSMYKRLTKTTTSGQGQCPGQDMEPQRERERKPILGIYLVGWGIALLICGISSAVNLAEYATYDYCFLHSSTTLNALLVPAVILVIFCGILALCIYYQLSQQAVNVLQLQMQHQQNRQYSDNNTQATEHIDLDWLDANGSATTAAIGGGSGNHGGRKEQDHMQEQYSTLSNPLSSIVDDFERSNLSHLRGHFIFLVLYAGAWLSAAAYVNGGQELYVLSFAGCCSVLGIFLLIFYNLSRNDARQAWSQGRDGRSIPAKLVTYNNGSQARGAHPSSMMPGPGTAMISNSIVAYKANPGPGSLYEANNSAGSRSNSQCSRSMRSQTRSQTRSQQEQLLQANGAGGVTIINNTSGQPGAGGGPAAGGVSGSTGGAPVPPHSLNALLHGSSHDLIPSAEIFYNPNQINVARKFFKKQKRLAKRNNFELQRQTMPQMQLQMQMQMQLHSQHSLSDASSEQLYSRHHNAMTMLAGGSKINNTNLHYKNQGSPMAGAPKEHGNMGAMSSGGDSMQFKRFVPASASSASKIMQANIYTNIPETLTPQHEVIKLRANGRTRTPSLLDETLHELDDDEEDEEEEEHGQTPATMEEPEHELEEEDASSLDEHAPLYANTLPPASGMSSLFRNRGSSHQPMSSTPVKQPSLEAMNSLGLPEVSLEEPLLQKHEIYVSNSLQVTTSNSIQLDDDFPSVLIRFSQQQQSKSLNNISEMLAGGGGGGGNAPGLDSLGDQQESSQLSVNEGSTLEEQQLRQIYSCSSSNLSQLKGHHPTATVDTEDDGRLLSGSPTNESDLNYQNSEISIRSHGLYAPQADNDLNLTLTDDFRCYQSSNASDADVDVLNEFDDEFVAATGGERVVGDAEQDPHHDHDQDTSIDELYEAIKCRSPLRNKQEAVERFERERERDREKEMEMEAKPLSNSHNENLNETIEDDSSQSSVISYIDPRAANEPRPFPS", "length": 1797 }, "evidence": [ { "id": "HGNC:17849", "url": "https://alliancegenome.org/gene/HGNC:17849#orthology", "database": "AGR" }, { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" }, { "id": "MGI:1925810", "url": "https://alliancegenome.org/gene/MGI:1925810#orthology", "database": "AGR" }, { "id": "RGD:2323365", "url": "https://alliancegenome.org/gene/RGD:2323365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-363#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7TT36-1", "protein_name": "Adhesion G protein-coupled receptor A3", "gene_name": "Adgra3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPPPPLLLLPLALLALLWGGERGAAALPAGCKHDGRARGTGRAAAAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISRIAPGAFWGLSSLKRLDLTNNRIGCLNADVFRGLTNLVRLNLSGNLFTSLSQGTFDYLGSLRSLEFQTEYLLCDCNILWMHRWVKERNITVRDTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHSSGIYPGSAQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTREEKSKELGDVMVDVASNIMLADERVLWLAQREAKACSRIVQCLQRIATHRLASGAHVYSTYSPNIALEAYVIKAAGFTGMTCSVFQKVAASDRAGLSDYGRRDPDGNLDKQLSFKCNVSSTFSSLALKNTIMEASIQLPSSLLSPKHKREARAADDALYKLQLIAFRNGKLFPATGNSTKLADDGKRRTVVTPVILTKIDGATVDTHHIPVNVTLRRIAHGADAVAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMDLTGTELYTPAASLLHPVVYTTAITLLLCLLAVIISYMYHHSLIRISLKSWHMLVNLCFHILLTCVVFVGGITQTRNASVCQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPAPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPSAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANENGEINHQDSMSLSLISTSTLENEHSFQSQLLGASLTLLLYVILWMFGAMAVSLYYPLDLVFSFFFGATCLSFSAFMMVHHCINREDVRLAWIMMCCPGRSSYSVQVNVQPPNSSATNGEAPKCTNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQYHSNALPVNATPQLDNSLTEHSMDNDIKMHVAPLDVQFRTNVHPSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRPGSNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNVEKPVSTSSKKDAPRKPAAADLESQQKSYGLNLAVQNGPVKSNGQEGPLLATDVTGNVRTGLWKHETTV", "length": 1310 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SQ6-3", "protein_name": "Adhesion G protein-coupled receptor A1", "gene_name": "ADGRA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLKTVLSLPRYPGEFLHPVVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNLQAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETTV", "length": 560 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C4G9-1", "protein_name": "Adhesion G protein-coupled receptor A1", "gene_name": "Adgra1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQWDLKTVLSLPQYPGEFLHPVVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTQHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPGADQPPYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFIALVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPESGHRHGVRPGTPPTCDALAASQLQNEHSFKAQLRAAAFTLFLFTATWTFGALAVSQGHFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWSCCPSRGDTSTTKPGAHPTLDANGDALGHTACLQDSPCPGKLRGFGHPPASHCKMTNLQAAQGHVSCLSPATPCCAKMHCEQLMEEEAAHIHMAEEDVYPHDPHLHDPHLHRCLKGRTKSHYFSRHQAAAAEREYAYHIPSSLDGSPHSSRSESPTSSLEGPMGMHTLACCAQADPFPMVSQPEGGDTSPGLYGCPPHLSPGPAHLEMLRRTQSLPFGGPSQNGLLQGDVREGLPFGTDGTGNIRTGPWKNETTV", "length": 578 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWK6-1", "protein_name": "Adhesion G protein-coupled receptor A3", "gene_name": "ADGRA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPPGRRRGRAQPPLLLPLSLLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLDLTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCNILWMHRWVKEKNITVRDTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHGSGIYPGNPQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTKEEKSKELGDVMVDIASNIMLADERVLWLAQREAKACSRIVQCLQRIATYRLAGGAHVYSTYSPNIALEAYVIKSTGFTGMTCTVFQKVAASDRTGLSDYGRRDPEGNLDKQLSFKCNVSNTFSSLALKNTIVEASIQLPPSLFSPKQKRELRPTDDSLYKLQLIAFRNGKLFPATGNSTNLADDGKRRTVVTPVILTKIDGVNVDTHHIPVNVTLRRIAHGADAVAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQAASLLHPVVYTTAIILLLCLLAVIVSYIYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANENGEINHQDSMSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYYPLDLVFSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVNVQPPNSNGTNGEAPKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNSLTEHSMDNDIKMHVAPLEVQFRTNVHSSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRLGNNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNFEKPVSTTSKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEGPLLGTDSTGNVRTGLWKHETTV", "length": 1321 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZV8-1", "protein_name": "Adhesion G protein-coupled receptor A2", "gene_name": "Adgra2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAGGRRMPVPPARLLLLPLLPCLLLLAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNPARRRVVCGGGDLPEPPDPGLLPNGTITLLLSNNKITGLRNGSFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIYSSLQPGVFDELPALKIVDFGTEFLTCDCRLRWLLPWARNHSLQLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGNDTRIHWYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQGNTSKKVEIVVLETSASYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTAFQRREVGVSGAQPSSVGQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPSLFSTLPAALAPPVPPDCTLQLLVFRNGRLFRSHGNNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGADPMAAWWNQDGPGGWSSEGCRLRYSQPNVSSLYCQHLGNVAVLMELNAFPREAGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFVGGVTLTNYQMVCQAVGITLHYSSLSSLLWMGVKARVLHKELSWRAPPLEEGEAAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILPITWIYFLCAGLHLRSHVAQNPKQGNRISLEPGEELRGSTRLRSSGVLLNDSGSLLATVSAGVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPSASHVPARALPTATEDGSPVLGEGPASLKSSPSGSSGRAPPPPCKLTNLQVAQSQVCEASVAARGDGEPEPTGSRGSLAPRHHNNLHHGRRVHKSRAKGHRAGETGGKSRLKALRAGTSPGAPELLSSESGSLHNSPSDSYPGSSRNSPGDGLPLEGEPMLTPSEGSDTSAAPIAETGRPGQRRSASRDNLKGSGSALERESKRRSYPLNTTSLNGAPKGGKYEDASVTGAEAIAGGSMKTGLWKSETTV", "length": 1336 }, "evidence": [ { "id": "HGNC:17849", "url": "https://alliancegenome.org/gene/HGNC:17849#orthology", "database": "AGR" }, { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" }, { "id": "MGI:1925810", "url": "https://alliancegenome.org/gene/MGI:1925810#orthology", "database": "AGR" }, { "id": "RGD:2323365", "url": "https://alliancegenome.org/gene/RGD:2323365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-363#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PE1-1", "protein_name": "Adhesion G protein-coupled receptor A2", "gene_name": "ADGRA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAGGRRMRGAPARLLLPLLPWLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPAAPHAPPRALPAAAEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQLAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSESGSLHNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSAAPLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV", "length": 1338 }, "evidence": [ { "id": "HGNC:17849", "url": "https://alliancegenome.org/gene/HGNC:17849#orthology", "database": "AGR" }, { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" }, { "id": "MGI:1925810", "url": "https://alliancegenome.org/gene/MGI:1925810#orthology", "database": "AGR" }, { "id": "RGD:2323365", "url": "https://alliancegenome.org/gene/RGD:2323365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-363#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "S4X0Q8-1", "protein_name": "Adhesion G protein-coupled receptor A3", "gene_name": "adgra3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVLCVLLLAFVLPLRGSSSAGSTECKTYDERSRSAGKSSPSGATLDRKVVCSNMEFRQVPSPDTFPNRTVSLILSNNKIQELLNGSFVGLSSLERLDIKNNIITHIEPGAFYGLFSLKRLDLSKNLIGCLHVDVFKGLTNLVKLNLSENKFSSLSQGIFDSLGSLKILEFDSPYLLCDCNLQWLVVWIKEKAIGVKETRCSFPRSLQGQLITTLRAETLTCDAPLELPSFQMTPSQHQIVFQGDSLPFQCMASFVDEDMQVLWYQDGKMVEPDATQGIYIEKSMVQNCSLIASALTISNIQPGFTGNWECRVRTSRGNNTRTVHIVVLESSAKYCLPDRVSNNKGEYRWPRTLAGITAYLPCKRQVTGAGIYSGSSAEDRRAWRRCDRGGQWAEDDYSRCEYMKDVTRVLYIINQMPLNLTNVVQTAQQLLAYTAEAPNFSDKVDVIFVAEMIEKIGKFAEKYKELGDVMVDISSNLLLADERVLWMAQREARACSRMVESLQRIALLRVSNGALAYSTNSPNIALEAHAIKASSFNGMTCTLFQKLSPERTVMAHHGEISPERQLSFKCNVTSNLSALALKNTIVEASLQLPPTLFSSLGSSGQAEEAVYKLHLLAFRNGKLFPPTGNSSILSDGSKRRSVVTPVMITKIEGFPLRDLLSPVNVTLRRFLQGSDAVPAFWNFSLQGGQGGWQSDGCRILHQDDNFTTVSCHSLNSYAVLMDLNRTGYNVFIFRPLHPVIYSTALVLVLCLLSVIVSYIYHHKSVRISKKCWHMLVNLCLHILLTCAVFVGGINQTYNASVCQAMGIVLHYSTLATALWSGVTARNIYKQVTRKAKRYEELDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSQVNAPYCWMAWEPSLGAFYGPAAFIVFVDCMYFLSILIQLRRHPERRFELKEQSEEQQHLSVTEATEITPVHLESSPTAQPVPMSALENEHTFVSQLMGVAGSLTLYAALWVFGALAISQEHPADLVFACLFGALALGLGAFLVAHHCVNRQDMRRHWSQACCLIRRNYAVQVDSLLLPIAGSSGSVMTSRGNGEATKCPASSAESSCTNKSAPSLRNSTQGCKLTNLQVEAAQCKVVAPSTANGTAVLDNSLTEHSVDNEIKMHVAPIEIQYRPSSVNNNNLPGNANITGHPGRHHKNRSRAHRASRLTVLREYSYDVPTSVEGSVQSVPNKRHHHESLHARNSRRAAYLAYRERQQSQLQQDSSDAASTSVPRRSRHFSKGTRIGNGFGHGISNGGLLDGSEADVTNQTKECPKQTLTVELEVQPKSYGLNLACQNGSAKDSERLNVESSGNVKTGLWKHETTV", "length": 1346 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "U3JAP0-1", "protein_name": "Adhesion G protein-coupled receptor A1", "gene_name": "adgra1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLKRVLSFPPYPGDYLHPVVYACTAVMLLCLLISIMTYIVHHSIIRISRKGWHMLLNFLFHTAMTFGVFAGGINQIKYPVICQVVGIILHYSSLSSMLWLLFTARNVCKEVSKAPPIPQDRDPPTQPRPKATIFRFYLVSGGVPLIIVGVTAAVNLDNYGSRDDAPYCWMAWEPSLGGFYGPTAFLVLVMCIYFLCTYVQLKRHPERKYELKAMTEEQQRLAVAEIGHCHAVSGEPGEHGDHTGCTAITASMLANEHSFKAQLRATAFTLFLFLATWVFGALAVSQGHFLDMIFSCLYGAFSVTLGLFLLIQHCAKRDDVWHRWWACCPNKPKVEVNGEAAGNAIPTTQSHSHTPSHGQNQIHCQVDSSCLGKPLLSPHLSPHCKLGSLPSTQNHTSTCCATLHSPSSLIGSSTRPQSLPDELPRPTLPLQSCLKDRSKTRSFNRPRPCLRDYSYHMTSTSMDGSVHSSHLDSPHSVHLDNPLTCHTSHLDTQLSCHSPHPDNQLRCPSPIPHLETLASHGLHDSLSCHSAHLDSQLSCHRHMCCAKADPFSSICCPNADPFVSPCQAEDPDMGSLMYSCAKMADKEDESMLHLDITPPRVSHATLGRKGTLSRRGTLSRNSSQHEDYAITSDSTGNIRTGPWKNETTV", "length": 650 }, "evidence": [ { "id": "FB:FBgn0030466", "url": "https://alliancegenome.org/gene/FB:FBgn0030466#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "Wnt signalosome", "id": "GO:1990909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990909", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "central nervous system vasculogenesis", "id": "GO:0022009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022009", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "dorsal root ganglion development", "id": "GO:1990791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990791", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" }, { "name": "Wnt-Frizzled-LRP5/6 complex assembly", "id": "GO:1904701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904701", "evidence": [ { "database": "UniProtKB", "id": "A0A0U2ULT4", "url": "https://www.uniprot.org/uniprotkb/A0A0U2ULT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1314, "end_pos": 1316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1318, "end_pos": 1320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1332, "end_pos": 1334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 47, 1066 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1128, "end_pos": 1130 }, { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 1226, "end_pos": 1228 }, { "start_pos": 1314, "end_pos": 1316 }, { "start_pos": 1318, "end_pos": 1320 }, { "start_pos": 1332, "end_pos": 1334 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 661, "end_pos": 663 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 89, "end_pos": 91 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }