{ "uniprot_canonical_ac": "A0A0R4IL45-1", "uniprot_ac": "A0A0R4IL45", "uniprot_id": "A0A0R4IL45_DANRE", "mass": { "chemical_mass": 73055.0, "monoisotopic_mass": 73055.0 }, "refseq": { "ac": "XP_005174738", "name": "E3 ubiquitin-protein ligase TRIM32 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174738" }, "gene_names": [ { "name": "trim32", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45", "id": "A0A0R4IL45" }, { "name": "trim32", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174738", "id": "XP_005174738" } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45/entry#names_and_taxonomy", "id": "A0A0R4IL45" }, { "name": "2.3.2.27", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45/entry#names_and_taxonomy", "id": "A0A0R4IL45" }, { "name": "E3 ubiquitin-protein ligase TRIM32 isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174738", "id": "XP_005174738" } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005174738.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005174738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174738" } ] } ], "disease": [ { "disease_id": "DOID:0110133", "recommended_name": { "id": "DOID:0110133", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110133", "name": "Bardet-Biedl syndrome 11", "description": "A Bardet-Biedl syndrome that has_material_basis_in mutation in the TRIM32 gene on chromosome 9q33." }, "synonyms": [ { "id": "DOID:0110133", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110133", "name": "BBS11", "description": "" }, { "id": "MONDO:0014439", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014439", "name": "Bardet-Biedl syndrome 11", "description": "Any Bardet-Biedl syndrome in which the cause of the disease is a mutation in the TRIM32 gene." }, { "id": "MONDO:0014439", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014439", "name": "BBS11", "description": "" }, { "id": "MONDO:0014439", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014439", "name": "Bardet-Biedl syndrome 11", "description": "" }, { "id": "MONDO:0014439", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014439", "name": "Bardet-Biedl syndrome caused by mutation in TRIM32", "description": "" }, { "id": "MONDO:0014439", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014439", "name": "Bardet-Biedl syndrome type 11", "description": "" }, { "id": "MONDO:0014439", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014439", "name": "TRIM32 Bardet-Biedl syndrome", "description": "" }, { "id": "MIM:615988", "resource": "MIM", "url": "https://www.omim.org/entry/615988", "name": "Bardet-Biedl syndrome 11", "description": "Bardet-Biedl syndrome 11" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110133", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110133" } ] }, { "disease_id": "DOID:0110282", "recommended_name": { "id": "DOID:0110282", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110282", "name": "autosomal recessive limb-girdle muscular dystrophy type 2H", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in mutation in the gene encoding tripartite motif-containing protein-32 (TRIM32) on chromosome 9q." }, "synonyms": [ { "id": "DOID:0110282", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110282", "name": "LGMD2H", "description": "" }, { "id": "DOID:0110282", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110282", "name": "muscular dystrophy Hutterite type", "description": "" }, { "id": "DOID:0110282", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110282", "name": "sarcotubular myopathy", "description": "" }, { "id": "DOID:0110282", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110282", "name": "limb-girdle muscular dystrophy due to TRIM32 deficiency", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "autosomal recessive limb-girdle muscular dystrophy type 2H", "description": "Autosomal recessive limb-girdle muscular dystrophy type 2H (LGMD2H) is a mild subtype of autosomal recessive limb girdle muscular dystrophy characterized by slowly progressive proximal muscle weakness and wasting of the pelvic and shoulder girdles with onset that usually occurs during the second or third decade of life. Clinical presentation is variable and can include calf psuedohypertrophy, joint contractures, scapular winging, muscle cramping and/or facial and respiratory muscle involvement." }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "LGMD2H", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "Sarcotubular myopathy", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "TRIM32 autosomal recessive limb-girdle muscular dystrophy", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "autosomal recessive limb-girdle muscular dystrophy caused by mutation in TRIM32", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "autosomal recessive limb-girdle muscular dystrophy type 2H", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "limb-girdle muscular dystrophy due to TRIM32 deficiency", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "muscular dystrophy Hutterite type", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "muscular dystrophy, limb-girdle, autosomal recessive 8", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "sarcotubular myopathy", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "limb-girdle muscular dystrophy type 2H", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "muscular dystrophy limb-girdle type 2H", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "muscular dystrophy, Hutterite type", "description": "" }, { "id": "MONDO:0009683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009683", "name": "muscular dystrophy, limb-girdle, type 2H", "description": "" }, { "id": "MIM:254110", "resource": "MIM", "url": "https://www.omim.org/entry/254110", "name": "Muscular dystrophy, limb-girdle, autosomal recessive 8", "description": "Muscular dystrophy, limb-girdle, autosomal recessive 8" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110282" } ] }, { "disease_id": "DOID:1935", "recommended_name": { "id": "DOID:1935", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases." }, "synonyms": [ { "id": "MONDO:0008854", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008854", "name": "Bardet-Biedl syndrome 1", "description": "A Bardet-Biedl syndrome that has material basis in homozygous mutation in the BBS1 gene on chromosome 11q13." }, { "id": "MONDO:0008854", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008854", "name": "BBS1", "description": "" }, { "id": "MONDO:0008854", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008854", "name": "Bardet-Biedl syndrome 1", "description": "" }, { "id": "MONDO:0008854", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008854", "name": "Bardet-Biedl syndrome 1, modifier of", "description": "" }, { "id": "MONDO:0008854", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008854", "name": "Bardet-Biedl syndrome type 1", "description": "" }, { "id": "MIM:209900", "resource": "MIM", "url": "https://www.omim.org/entry/209900", "name": "Bardet-Biedl syndrome", "description": "Bardet-Biedl syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ] }, { "disease_id": "DOID:9884", "recommended_name": { "id": "DOID:9884", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration." }, "synonyms": [ { "id": "MONDO:0010678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010678", "name": "muscular dystrophy, progressive Pectorodorsal", "description": "" }, { "id": "MONDO:0010678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010678", "name": "muscular dystrophy, progressive Pectorodorsal", "description": "" }, { "id": "MONDO:0010678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010678", "name": "muscular dystrophy, progressive, involving shoulder girdle and back", "description": "" }, { "id": "MONDO:0010884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010884", "name": "muscular dystrophy, scapulohumeral", "description": "" }, { "id": "MONDO:0010884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010884", "name": "muscular dystrophy, scapulohumeral", "description": "" }, { "id": "MONDO:0010676", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010676", "name": "muscular dystrophy, Hemizygous lethal type", "description": "" }, { "id": "MONDO:0010676", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010676", "name": "muscular dystrophy, Hemizygous lethal type", "description": "" }, { "id": "MONDO:0010675", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010675", "name": "muscular dystrophy, cardiac type", "description": "" }, { "id": "MONDO:0010675", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010675", "name": "muscular dystrophy, cardiac type", "description": "" }, { "id": "MONDO:0010677", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010677", "name": "muscular dystrophy, Mabry type", "description": "" }, { "id": "MONDO:0010677", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010677", "name": "muscular dystrophy, Mabry type", "description": "" }, { "id": "MONDO:0008028", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008028", "name": "muscular dystrophy, Barnes type", "description": "" }, { "id": "MONDO:0008028", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008028", "name": "muscular dystrophy, Barnes type", "description": "" }, { "id": "MONDO:0008034", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008034", "name": "muscular dystrophy, pseudohypertrophic, with Internalized capillaries", "description": "" }, { "id": "MONDO:0008034", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008034", "name": "muscular dystrophy, pseudohypertrophic, with Internalized capillaries", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "trim32", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060428-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060428-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000102505", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000102505", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14961", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14961", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16587", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16587", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19806", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19806", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "562764", "url": "https://www.ncbi.nlm.nih.gov/gene/562764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562764", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPTMFQL", "url": "https://omabrowser.org/oma/group/LPTMFQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0R4IL45", "url": "https://www.orthodb.org/?gene=A0A0R4IL45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A8WGA9", "url": "https://www.orthodb.org/?gene=A8WGA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25464", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25464", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25464:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25464:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01436", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_005174738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174738", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4IL45-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8WGA9-1", "url": "https://www.uniprot.org/uniprotkb/A8WGA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060428-1", "url": "https://zfin.org/ZDB-GENE-060428-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MATSTSLDPELVREVLECPICLETYNQDQLRPKLLQCGHSVCRQCLEKLLASTINGVRCPFCSKVSRMSSISQLADNLTVLKIIDCASACSSNMGLMCKSCKNRLPRQYCCDCSIVLCDICKNEGHQRQGHVVQAIRMAAELRRKDIGAKLSDLREAMGNIQKKKAAIDNVTKSLRMKYKAVQQEYAKAELRLQEELGRSRRAFAASLAEIEKLNAQILEEQTYLLNIAEVQVVSRCDYLTMRIKQTDIALLEEGSNNDEEEDLDLKTNLPVVLKLQDPELVKIENSKSLEVGQLTTKPCNVNVEEEEDGLDFPTATSAPLDIYRDIDMVPAVEEAVCASPGSFKSKSVDGGGPSPGASGGQLCQFVKKMGCKGNLPGMFNLPVSICVTLQGEVLVADRGNYRIQIFNRKGFQREIRRNPSSIDNFVLSFLGADLPNLIPLSIAITAQGLIGVTDNYDNSVKVYTTDGHCIACHKNQLIKPWGIAAMPSGQFVVSDVEGGKLWCLAVDRNVGVVNYNRLCSAVRPKFVTCDSSGTVYFTQGLGLNIENRHNEHHLEGGFSIGSVGMDGQLGKQLSHFFSETEDFRCITGMCVDSNGDLIVTDSGRKEILQFPKEGGYNILIQEGLTCPVGVAVTQKGQLLVLDCWDHCVKVYTYLQRRRSSTC", "length": 663, "header": "tr|A0A0R4IL45-1|A0A0R4IL45_DANRE Isoform 1 of RING-type E3 ubiquitin transferase OS=Danio rerio OX=7955 GN=trim32 PE=3 SV=1 CANONICAL=A0A0R4IL45-1" }, "isoforms": [ { "isoform_ac": "A0A0R4IL45-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45/entry#A0A0R4IL45-1", "sequence": { "sequence": "MATSTSLDPELVREVLECPICLETYNQDQLRPKLLQCGHSVCRQCLEKLLASTINGVRCPFCSKVSRMSSISQLADNLTVLKIIDCASACSSNMGLMCKSCKNRLPRQYCCDCSIVLCDICKNEGHQRQGHVVQAIRMAAELRRKDIGAKLSDLREAMGNIQKKKAAIDNVTKSLRMKYKAVQQEYAKAELRLQEELGRSRRAFAASLAEIEKLNAQILEEQTYLLNIAEVQVVSRCDYLTMRIKQTDIALLEEGSNNDEEEDLDLKTNLPVVLKLQDPELVKIENSKSLEVGQLTTKPCNVNVEEEEDGLDFPTATSAPLDIYRDIDMVPAVEEAVCASPGSFKSKSVDGGGPSPGASGGQLCQFVKKMGCKGNLPGMFNLPVSICVTLQGEVLVADRGNYRIQIFNRKGFQREIRRNPSSIDNFVLSFLGADLPNLIPLSIAITAQGLIGVTDNYDNSVKVYTTDGHCIACHKNQLIKPWGIAAMPSGQFVVSDVEGGKLWCLAVDRNVGVVNYNRLCSAVRPKFVTCDSSGTVYFTQGLGLNIENRHNEHHLEGGFSIGSVGMDGQLGKQLSHFFSETEDFRCITGMCVDSNGDLIVTDSGRKEILQFPKEGGYNILIQEGLTCPVGVAVTQKGQLLVLDCWDHCVKVYTYLQRRRSSTC", "length": 663, "header": "tr|A0A0R4IL45-1|A0A0R4IL45_DANRE Isoform 1 of RING-type E3 ubiquitin transferase OS=Danio rerio OX=7955 GN=trim32 PE=3 SV=1 CANONICAL=A0A0R4IL45-1" }, "locus": {} }, { "isoform_ac": "A8WGA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45/entry#A8WGA9-1", "sequence": { "sequence": "MATPTSLDPELVREVLECPICLETYNQDQLRPKLLQCGHSVCRQCLEKLLASTINGVRCPFCSKVSRMSSISQLADNLTVLKIIDCASACSSNMGLMCKSCKNRLPRQYCCDCSIVLCDICKNEGHQRQGHVVQAIRMAAELRRKDIGAKLSDLREAMGNIQKKKAAIDNVTKSLRMKYKAVQQEYAKAELRLQEELGRSRRAFAASLAEIEKLNAQILEEQTYLLNIAEVQVVSRCDYLTMRIKQTDIALLEEGSNNDEEEDLDLKTNLPVVLKLQDPELVKIENSKSLEVGQLTTKPCNVNVEEEEDGLDFPTATSAPLDIYRDIDMVPAVEEAVCASPGSFKSKSVDGGGPSPGASGGQLCQFVKKMGCKGNLPGMFNLPVSICVTLQGEVLVADRGNYRIQIFNRKGFQREIRRNPSSIDNFVLSFLGADLPNLIPLSIAITAQGLIGVTDNYDNSVKVYTTDGHCIACHKNQLIKPWGIAAMPSGQFVVSDVEGGKLWCLAVDRNVGVVNYNRLCSAVRPKFVTCDSSGTVYFTQGLGLNIENRHNEHHLEGGFSIGSVGMDGQLGKQLSHFFSETEDFRCITGMCVDSNGDLIVTDSGRKEILQFPKEGGYNILIQEGLTCPVGVAVTQKGQLLVLDCWDHCVKVYTYLQRRRSSTC", "length": 663, "header": "tr|A8WGA9-1|A0A0R4IL45_DANRE Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Danio rerio OX=7955 GN=trim32 PE=3 SV=1 CANONICAL=A0A0R4IL45-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11).", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2006", "authors": "Chiang AP, Beck JS, Yen HJ, Tayeh MK, Scheetz TE, Swiderski RE, Nishimura DY, Braun TA, Kim KY, Huang J, Elbedour K, Carmi R, Slusarski DC, Casavant TL, Stone EM, Sheffield VC", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "16606853", "url": "https://glygen.org/publication/PubMed/16606853" } ] }, { "title": "Bardet-Biedl syndrome: an emerging pathomechanism of intracellular transport.", "journal": "Cell. Mol. Life Sci.", "date": "2006", "authors": "Blacque O E, Leroux M R", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "16909204", "url": "https://glygen.org/publication/PubMed/16909204" } ] }, { "title": "Zebrafish orthologs of human muscular dystrophy genes.", "journal": "BMC Genomics", "date": "2007", "authors": "Steffen Leta S, Guyon Jeffrey R, Vogel Emily D, Beltre Rosanna, Pusack Timothy J, Zhou Yi, Zon Leonard I, Kunkel Louis M", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "17374169", "url": "https://glygen.org/publication/PubMed/17374169" } ] }, { "title": "Genetic interaction between Bardet-Biedl syndrome genes and implications for limb patterning.", "journal": "Hum. Mol. Genet.", "date": "2008", "authors": "Tayeh Marwan K, Yen Hsan-Jan, Beck John S, Searby Charles C, Westfall Trudi A, Griesbach Hilary, Sheffield Val C, Slusarski Diane C", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "18381349", "url": "https://glygen.org/publication/PubMed/18381349" } ] }, { "title": "A BBSome subunit links ciliogenesis, microtubule stability and acetylation.", "journal": "Dev. Cell", "date": "2008", "authors": "Loktev AV, Zhang Q, Beck JS, Searby CC, Scheetz TE, Bazan JF, Slusarski DC, Sheffield VC, Jackson PK, Nachury MV", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "19081074", "url": "https://glygen.org/publication/PubMed/19081074" } ] }, { "title": "Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2010", "authors": "Zaghloul Norann A, Liu Yangjian, Gerdes Jantje M, Gascue Cecilia, Oh Edwin C, Leitch Carmen C, Bromberg Yana, Binkley Jonathan, Leibel Rudolph L, Sidow Arend, Badano Jose L, Katsanis Nicholas", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "20498079", "url": "https://glygen.org/publication/PubMed/20498079" } ] }, { "title": "Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish.", "journal": "PLoS ONE", "date": "2011", "authors": "Boudinot Pierre, van der Aa Lieke M, Jouneau Luc, Du Pasquier Louis, Pontarotti Pierre, Briolat Val\u00e9rie, Benmansour Abdenour, Levraud Jean-Pierre", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "21789205", "url": "https://glygen.org/publication/PubMed/21789205" } ] }, { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] }, { "title": "eIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation.", "journal": "PLoS Biol.", "date": "2013", "authors": "Yogev Orli, Williams Victoria C, Hinits Yaniv, Hughes Simon M", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "24143132", "url": "https://glygen.org/publication/PubMed/24143132" } ] }, { "title": "Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7.", "journal": "J. Biol. Chem.", "date": "2014", "authors": "Ramachandran Haribaskar, Sch\u00e4fer Tobias, Kim Yunhee, Herfurth Konstantin, Hoff Sylvia, Lienkamp Soeren S, Kramer-Zucker Albrecht, Walz Gerd", "evidence": [ { "database": "UniProtKB", "id": "A8WGA9", "url": "https://www.uniprot.org/uniprotkb/A8WGA9" } ], "reference": [ { "type": "PubMed", "id": "24500717", "url": "https://glygen.org/publication/PubMed/24500717" } ] } ], "pathway": [ { "id": "dre:562764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562764", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AKB8-1", "protein_name": "E3 ubiquitin-protein ligase TRIM32", "gene_name": "TRIM32", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASAPQLNSDALREVLECPICMESFTEEHLRPKLLHCGHTICKQCLEKLLATSINGIRCPFCSKITRIKTLAQLTDNLTVLKIIDTTGLGEVVGLLMCKVCGRRLPRHFCKSCGLVLCEPCKETSHMPQGHNVIAIKEAAEERRREFGTRLARLRELMDELQKRKASLEGVSSDLQSRYRAVLQDYSKEERKIQEELARSRKFFTTSLSEVEKVNNQVMEEQAYLLNLAEVQILSRCDYFLAKIKQGDIALLEEAADEEEPELTSSLPGELILHEVELLKVSHVGPLQIGQVVKKPRTVNLEESLMETAASSSASFREPDLVQEEASCTPNTSPAKPRMPEAAASIQQCHFIKKMGSKGSLPGMFNLPVSLYVTLQGEVLVADRGNFRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVTMNCHGLIGVTDSYDNSVKVYTMDGHCVACHRSQLSKPWGIAALPSGQFVVTDVEGGKLWCFTVDRGVGVVKYTCLCSAVRPKFVTCDAEGTIYFTQGLGLNLENRQYEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYNILIREGLTCPVGIAITPKGQLLVLDCWDHCIKIYSYHLRRYSTP", "length": 647 }, "evidence": [ { "id": "A0A0R4IL45", "url": "https://omabrowser.org/oma/group/A0A0R4IL45/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SMI2-1", "protein_name": "E3 ubiquitin-protein ligase TRIM32", "gene_name": "TRIM32", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLSQLTDNLTVLKIIDTAGLSEAVGLLMCRACGRRLPRQFCRSCSVVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLARLRELMGELQRRKVALEGVSKDLQARYKAVLQEYGHEERRVQEELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETAEEEEPELTASLPHELTLQDVELLKVGHVGPLQIGQAVKKPRTVNMEDSWAMEAAASAASTSVTFREMDMSPEEVASPRASPAKQRGAETAASIQQCLFLKKMGAKGSTPGMFNLPVSLYVTGQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCHGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGAGVVKYSCLCSAVRPKFVTCDTEGTVYFTQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP", "length": 652 }, "evidence": [ { "id": "A0A0R4IL45", "url": "https://omabrowser.org/oma/group/A0A0R4IL45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0VCP5-1", "protein_name": "E3 ubiquitin-protein ligase TRIM32", "gene_name": "TRIM32", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAAASHLNLDALREVLECPICLESFTEEQLRPKLLHCGHTICCRCLEKLLASSINGVRCPFCSKITLITSLAQLTDNLTVLKIIDKTGLSEAVGLLMCRSCGRRLPRQFCRSCGVVVCEPCREAEHPPPGHCTLPVKEAAEERRQDFGRKLARLRELTGELQRRKVALEGVSKDLQARYKAVLQEYGHEERRVQEELARSRKFFTGSVAEVEKSNSQLVEEQSYLLNVAEVQAVSRCDYFLAKIKQADVALLEEAADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNMEDSWAMEAAASAAPSSVTFREMDVSPEDMGASPRASPAKQRGSDPATNIQQCLFLRKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSSSAMDSFVLSFFGADPPNLTPLSVAMNCHGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGAGVVKYSCLCSAVRPKFVACDAEGTVYFTQGLGLNLENWQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCITGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP", "length": 653 }, "evidence": [ { "id": "A0A0R4IL45", "url": "https://omabrowser.org/oma/group/A0A0R4IL45/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q13049-1", "protein_name": "E3 ubiquitin-protein ligase TRIM32", "gene_name": "TRIM32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP", "length": 653 }, "evidence": [ { "id": "RGD:1305238", "url": "https://alliancegenome.org/gene/RGD:1305238#orthology", "database": "AGR" }, { "id": "MGI:1917057", "url": "https://alliancegenome.org/gene/MGI:1917057#orthology", "database": "AGR" }, { "id": "HGNC:16380", "url": "https://alliancegenome.org/gene/HGNC:16380#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060428-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060428-1#orthology", "database": "AGR" }, { "id": "A0A0R4IL45", "url": "https://omabrowser.org/oma/group/A0A0R4IL45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66H79-1", "protein_name": "E3 ubiquitin-protein ligase TRIM32", "gene_name": "Trim32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRACGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELTGELQRRKAALEGVSRDLQARYKAVLQEYGHEERRVQEELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNMEDSWAVEEGAASSASASVTFREMDMSPEEVVPSPRASPAKQRSSEAASSIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQSEVLVADRGNYRIQVFNRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCHGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGAGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNVENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCVKIYSYHLRRYSTP", "length": 655 }, "evidence": [ { "id": "RGD:1305238", "url": "https://alliancegenome.org/gene/RGD:1305238#orthology", "database": "AGR" }, { "id": "MGI:1917057", "url": "https://alliancegenome.org/gene/MGI:1917057#orthology", "database": "AGR" }, { "id": "HGNC:16380", "url": "https://alliancegenome.org/gene/HGNC:16380#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060428-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060428-1#orthology", "database": "AGR" }, { "id": "A0A0R4IL45", "url": "https://omabrowser.org/oma/group/A0A0R4IL45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CH72-1", "protein_name": "E3 ubiquitin-protein ligase TRIM32", "gene_name": "Trim32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRGCGRRLPRQFCRSCGVVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELTGELQRRKAALEGVSRDLQARYKAVLQEYGHEERRIQEELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNMEDSWAGEEGAASSASASVTFREMDMSPEEVAPSPRASPAKQRSSEAASGIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQSEVLVADRGNYRIQVFNRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCHGLIGVTDSYDNSLKVYTMDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGAGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNVENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCVKIYSYHLRRYSTP", "length": 655 }, "evidence": [ { "id": "RGD:1305238", "url": "https://alliancegenome.org/gene/RGD:1305238#orthology", "database": "AGR" }, { "id": "MGI:1917057", "url": "https://alliancegenome.org/gene/MGI:1917057#orthology", "database": "AGR" }, { "id": "HGNC:16380", "url": "https://alliancegenome.org/gene/HGNC:16380#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060428-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060428-1#orthology", "database": "AGR" }, { "id": "A0A0R4IL45", "url": "https://omabrowser.org/oma/group/A0A0R4IL45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of autophagy", 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starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45" } ], "pmid": "" }, { "name": "melanosome transport", "id": "GO:0032402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032402", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:1903265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903265", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IL45", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IL45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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