{ "uniprot_canonical_ac": "A0A0R4IIK0-1", "uniprot_ac": "A0A0R4IIK0", "uniprot_id": "A0A0R4IIK0_DANRE", "mass": { "chemical_mass": 54972.0, "monoisotopic_mass": 54972.0 }, "refseq": { "ac": "NP_001152984", "name": "transmembrane protease serine 13a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984" }, "gene_names": [ { "name": "tmprss13a", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0", "id": "A0A0R4IIK0" }, { "name": "tmprss13a", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984", "id": "NP_001152984" } ], "protein_names": [ { "name": "Transmembrane protease serine 13a", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0/entry#names_and_taxonomy", "id": "A0A0R4IIK0" }, { "name": "Transmembrane serine protease 13a", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0/entry#names_and_taxonomy", "id": "A0A0R4IIK0" }, { "name": "transmembrane protease serine 13a", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984", "id": "NP_001152984" }, { "name": "transmembrane protease, serine 13a", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984", "id": "NP_001152984" } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01008250.1, GFIL01041325.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001152984.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001152984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmprss13a", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090309-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090309-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000100969", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000100969", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "559754", "url": "https://www.ncbi.nlm.nih.gov/gene/559754", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559754", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559754", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PWIYSNM", "url": "https://omabrowser.org/oma/group/PWIYSNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0R4IIK0", "url": "https://www.orthodb.org/?gene=A0A0R4IIK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF15494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15494", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001152984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4IIK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090309-3", "url": "https://zfin.org/ZDB-GENE-090309-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEDNDTKDPPPPYYSVAMEPQAPPMTYEEVIFQDKYGVTQNTVPYYIPKEPPQVHVAAVIVTQGVVTPRRQQSCGRTAKCWGGLVGVLLVLGLIAVAIWLGVHYGSQPNSEHGNNDNNDNNCMEDDCSSEESHFEGAHDGIKVPPTYSSSSLLCDGVQHYQHGIDEMDCVRFGAGGELQLKTAHNGQFLPVCYEGWNISYADQICEQLGFRRSYESSALNSKSSEALILEPTSGLLIQGLANVSSGCLDDKSVSLQCSDCGKQQSSSRIIGGTTSELGQYPWQVSLHYNKAHVCGGTLISPDFIVSAAHCFQGKMANSAYWLVYVGIVSQQSLGMPYLVKKIIVSEKYNSDTNDNDVALLILSRPVAFSYTTQPVCLPTFNQTFSGGLQCWTSGFGTTKQGADRASSSLMSVSVNIIDSSVCNSCQIYCGLITNNMICAGDLKGGRDSCQGDSGGPLVCKDDNNRWYLVGITSWGAGCGQKQKPGVYSRVTSFLPWIYTKMQQEKP", "length": 506, "header": "tr|A0A0R4IIK0-1|A0A0R4IIK0_DANRE Isoform 1 of Transmembrane serine protease 13a OS=Danio rerio OX=7955 GN=tmprss13a PE=4 SV=1 CANONICAL=A0A0R4IIK0-1" }, "isoforms": [ { "isoform_ac": "A0A0R4IIK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0/entry#A0A0R4IIK0-1", "sequence": { "sequence": "MEDNDTKDPPPPYYSVAMEPQAPPMTYEEVIFQDKYGVTQNTVPYYIPKEPPQVHVAAVIVTQGVVTPRRQQSCGRTAKCWGGLVGVLLVLGLIAVAIWLGVHYGSQPNSEHGNNDNNDNNCMEDDCSSEESHFEGAHDGIKVPPTYSSSSLLCDGVQHYQHGIDEMDCVRFGAGGELQLKTAHNGQFLPVCYEGWNISYADQICEQLGFRRSYESSALNSKSSEALILEPTSGLLIQGLANVSSGCLDDKSVSLQCSDCGKQQSSSRIIGGTTSELGQYPWQVSLHYNKAHVCGGTLISPDFIVSAAHCFQGKMANSAYWLVYVGIVSQQSLGMPYLVKKIIVSEKYNSDTNDNDVALLILSRPVAFSYTTQPVCLPTFNQTFSGGLQCWTSGFGTTKQGADRASSSLMSVSVNIIDSSVCNSCQIYCGLITNNMICAGDLKGGRDSCQGDSGGPLVCKDDNNRWYLVGITSWGAGCGQKQKPGVYSRVTSFLPWIYTKMQQEKP", "length": 506, "header": "tr|A0A0R4IIK0-1|A0A0R4IIK0_DANRE Isoform 1 of Transmembrane serine protease 13a OS=Danio rerio OX=7955 GN=tmprss13a PE=4 SV=1 CANONICAL=A0A0R4IIK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification and molecular characterization of the interleukin-10 receptor 1 of the zebrafish (Danio rerio) and the goldfish (Carassius auratus L.).", "journal": "Dev. Comp. Immunol.", "date": "2012", "authors": "Grayfer Leon, Belosevic Miodrag", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "reference": [ { "type": "PubMed", "id": "21906622", "url": "https://glygen.org/publication/PubMed/21906622" } ] }, { "title": "Pannexin 1 ohnologs in the teleost lineage.", "journal": "J. Membr. Biol.", "date": "2012", "authors": "Bond Stephen R, Wang Nan, Leybaert Luc, Naus Christian C", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "reference": [ { "type": "PubMed", "id": "22922822", "url": "https://glygen.org/publication/PubMed/22922822" } ] }, { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:559754", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559754", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A5PF55-1", "protein_name": "Transmembrane serine protease 13b", "gene_name": "tmprss13b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEHKQTEAPPSYDSVVTQNITPPPSYPSLQILSTTQVQPYYIPQPLPQIPAPHVVETTVPQQRTQAVSYRSKRCCYGGSTGIAAVVVLVVIAVYLGVRYGPSLWAFSERDAETDTCPGSAVNCDGRKDCSLGSDESQCVRIGTGNELQVLTSRSGSFLPVCAQGWNKNIADQTCQQLGFRQSYSYGVVKSNSPMFQSVNSQLVNNIQGRVNTSSSCPDQQSVSLQCCDCGRPPVSSRIIGGSVAAEGHWPWQASLHFQGKHSCGGSLVAPDFIITAAHCFPKETSGSQLPSNWKVYIGFVSQLKLPSPYYVKEIILHEKYNPTTKNYDIALLKLNKPASDVEPICLPVIGQTFPPAKQCWTTGFGVIRQGSNSVSTSLMEVTVSLIDSSVCNSPNVYNGEITENMQCAGDLRGGKDSCQGDSGGPLACKSNDGQWFLTGVTSWGEGCGQVNRPGVYSDVAKYLMWIYSKMQQARP", "length": 475 }, "evidence": [ { "id": "MGI:2682935", "url": "https://alliancegenome.org/gene/MGI:2682935#orthology", "database": "AGR" }, { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7FMG3-1", "protein_name": "Transmembrane serine protease 13", "gene_name": "Tmprss13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRGSHRNASPARPSPQASPARASPQASPARTPPPQASPARASPPQASPARASPARASPVRASPARAPPSRSSSGRSSSARSASTTSSPTRVYLVRAIPVGTVIRASPARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVLLLISLVISLILLYGGREPQSPRGIAVYFWRGHTGIKYKEPLESCPKHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSERTCQQLGFDSAYRTTEVAHRDVTSSFLLSEYNSTIQESLTRSECPSRRYVSLQCAHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKILEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALVRLSKPLTLSAHIHPACLPLHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWIYRKMESEVRFRKS", "length": 552 }, "evidence": [ { "id": "MGI:2682935", "url": "https://alliancegenome.org/gene/MGI:2682935#orthology", "database": "AGR" }, { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" }, { "id": "A0A0R4IIK0", "url": "https://omabrowser.org/oma/group/A0A0R4IIK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3N0B7-1", "protein_name": "Transmembrane serine protease 13", "gene_name": "TMPRSS13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERDSRRNASPAGTPPPRAFPGRAPAARASPSRSSSGRSSSTMSPLTTSSPTRVYLVRATPVGTVPVHASPAGPTPAARAARESPGITLPKFTWQEGQKRLLLIGCVLLLIALVVSLIILYGGREPQSPRGIAVYFWRGHTGVNYKEPRESCPSHAVRCDGVEDCKLKSDELGCVRFDWDKSLLKVYSGSSHQWLPVCSDSWNDSYSQKTCQQLGFESAYWTTKVDNRNVDSSFSVSEFNSTIQQSTYRSDCPSQQYVALQCSHCGLRAMTGRIVGGARAPESKWPWQVSLQFSRTHICGGTLIDAQWILTAAHCFFITREKILEGWKVYVGTNDLHHLPESASVAQIIINSNYSDDQDDYDIALMRLSKPLTLSAHVHPACLPMHGQTFGLNEICWITGFGKTKETDERTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNGRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEREMRFRKS", "length": 515 }, "evidence": [ { "id": "A0A0R4IIK0", "url": "https://omabrowser.org/oma/group/A0A0R4IIK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q05319-1", "protein_name": "Serine proteinase stubble", "gene_name": "Sb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKQPTLIRPRLRHRRSTPAAATKMCPKRHWLVNNRAAGSRGSGGAAARSRRSLDQIVEVLVALIVVNCLATAAAALITPPDSLESLGSLGIPSSSASSSEDDDDMSSGFYRIPHRLEGYPQLQQLQRGQNFKISPKPCSFGRVEGTCMFVWECIKSEGKHVGMCVDSFMFGSCCTHNYTDNIVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPHGAGTLVIRPSGPHHQGTLARPHPPPYQSKPTTASDLHGSASHPSSSSSSSSSSNPNSIWHTSTQQQQQQQHQQNQQNHWQMTTEPSFITKPRPTGWTKPGIVNLPMPARPSKPSKPTKKPIVYDRTPPPPPSVPPSTSTSTTSTSLIWPAQTHPPQPHRPTRPQLSPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTTTTRRTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISSSSSSSSGIVTSSQRPTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR", "length": 787 }, "evidence": [ { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5U405-1", "protein_name": "Transmembrane protease serine 13", "gene_name": "Tmprss13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRGSHRNSSPARTPPQASPARTSPARAPPQASPARTPPQASPARTPPQASPARAPPPQASPARASPARAPPSRSSSGRSSSARSASTTSSPTRVYLVRATPVGAVPIRASPARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVILLISLVISLILLFYFWRGHTGIKYKEPLESCPIHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSKRTCQQLGFDSAYRTTEVAHRDITSSFLLSEYNTTIQESLYRSQCSSRRYVSLQCSHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKLLEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWIYRKMESEVRFRKS", "length": 543 }, "evidence": [ { "id": "MGI:2682935", "url": "https://alliancegenome.org/gene/MGI:2682935#orthology", "database": "AGR" }, { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090309-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090309-3#orthology", "database": "AGR" }, { "id": "A0A0R4IIK0", "url": "https://omabrowser.org/oma/group/A0A0R4IIK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYE2-1", "protein_name": "Transmembrane protease serine 13", "gene_name": "TMPRSS13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEVRSLQQDTAPSRLGTSSGGDPGGAPRL", "length": 586 }, "evidence": [ { "id": "MGI:2682935", "url": "https://alliancegenome.org/gene/MGI:2682935#orthology", "database": "AGR" }, { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090309-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090309-3#orthology", "database": "AGR" }, { "id": "A0A0R4IIK0", "url": "https://omabrowser.org/oma/group/A0A0R4IIK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VR15-1", "protein_name": "3.4.21.-", "gene_name": "Dmel\\CG3355", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRVYLALPLLLLGIGLSLAQYQYQAPHQTLAQQFADVVDVVDPAEQSIKAVRPPKSRNQCTAKQNCFCGTPNVNRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHNFDGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVNEGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTADGCYCQS", "length": 314 }, "evidence": [ { "id": "MGI:2682935", "url": "https://alliancegenome.org/gene/MGI:2682935#orthology", "database": "AGR" }, { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUF0-1", "protein_name": "Uncharacterized protein, isoform C", "gene_name": "SP40", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLNPPAFLLLLALISICDRSWAVYNYKPPSRGYFYPKPERLPPLPVNGSTTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGGAKAFRVNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVRDRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTRDSCYCIN", "length": 374 }, "evidence": [ { "id": "MGI:2682935", "url": "https://alliancegenome.org/gene/MGI:2682935#orthology", "database": "AGR" }, { "id": "HGNC:29808", "url": "https://alliancegenome.org/gene/HGNC:29808#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IIK0", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IIK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 4, "end_pos": 6 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }