{ "uniprot_canonical_ac": "A0A0R4IB93-1", "uniprot_ac": "A0A0R4IB93", "uniprot_id": "UBP48_DANRE", "mass": { "chemical_mass": 120405.0, "monoisotopic_mass": 120405.0 }, "refseq": { "ac": "NP_001411018", "name": "ubiquitin carboxyl-terminal hydrolase 48", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411018" }, "gene_names": [ { "name": "usp48", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93", "id": "A0A0R4IB93" }, { "name": "im:7139343; zgc:112364", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411018", "id": "NP_001411018" }, { "name": "im:7139343", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93", "id": "A0A0R4IB93" }, { "name": "usp48", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411018", "id": "NP_001411018" }, { "name": "zgc:112364", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93", "id": "A0A0R4IB93" } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 48", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93/entry#names_and_taxonomy", "id": "A0A0R4IB93" }, { "name": "3.4.19.12", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93/entry#names_and_taxonomy", "id": "A0A0R4IB93" }, { "name": "Ubiquitin specific peptidase 48", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93/entry#names_and_taxonomy", "id": "A0A0R4IB93" }, { "name": "ubiquitin carboxyl-terminal hydrolase 48", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411018", "id": "NP_001411018" } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01042872.1, GDQH01015490.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 25, 2025 this sequence version replaced NP_001411018.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001411018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411018" } ] }, { "annotation": "Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IB93", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93#function" }, { "database": "UniProtKB", "id": "Q86UV5", "url": "https://www.uniprot.org/uniprotkb/Q86UV5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IB93", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "usp48", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93", "locus": {} } ], "crossref": [ { "id": "A0A0R4IB93", "url": "https://alphafold.ebi.ac.uk/entry/A0A0R4IB93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000090301", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090301", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02668", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02668", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100332674", "url": "https://www.ncbi.nlm.nih.gov/gene/100332674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100332674", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A0R4IB93", "url": "https://www.orthodb.org/?gene=A0A0R4IB93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF722", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF722", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF06337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06337", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_A0A0R4IB93", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:PR_A0A0R4IB93", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001411018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0R4IB93", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4IB93-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13AAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRLQLEKAAWRWAEAVRPEDITHEHIELAYRIAVSACKRGACRRNCKGNPNCLVGIGEQSWLGEIDENTFHNIDDPNSERRDKNTFVGLTNLGATCYVNTFLQVWFHNLELRRALYRFQNSRAEGHNTDSDYEPRTICEHLQYLFALLQNSNRRYIDPSGLVKALGLDTGQQQDAQEFSKLFLSLLEDTLSKQKDPNLQNVIQQQFCGQFSYVTVCNKCGRESPLPSRFYELELNIQGHKNLTECVTEFLKEEKLDGDNRYYCESCQSKQNATRRIKLQSLPRTLNFQLMRFVFDRQSGHKKKLNTFISFPEVLDMEPFLEGREEKCTYELSAVLIHRGVSAYSGHYIAHVRDAHTNDWYKFNDEEIEKMEGKKLQLGIEEDIAETAKSQTRKPKCSKGYHCSRNAYMLVYKQQTEEINQTESPVDVPAFLQKLVEQDNRKFEEWCSEMSDMRKQSVDKGKAKHEEVKELYELLPAEDGQSYEFVPLEWLKKWLDDSTAIKEIDNSQFLCTHGKLHPDKIGEAKRISLKAADLLFSRYGGGPRLDRSSLCRDCVTQRCRVIRLKNQLNEDYREVTNLAKSALKSEESGFWIGKASLRSWRQLALDQLEEDEEETKHNNSKINGEKSSPGTKADGVKGDSEDGDGEEMKNFNEDILCYHGGLSILENDRRLVSAEVWNKLRMYFPKAPEFTQDHDPCQQCMRLEREGKENEALNRMMANEQKSSLLNLFQEKNRPTLQKWPQDTDILYIVPLYFVEEWKKFIRRPAKGNPVSNVGNSILLCPHGGFMFTYDSMLQGDAQHIALLWPAEWEVISKMFLVDQVISICRIHDKTQDNGNVQYQTHPDLCRECREGFIFQQQRDMREYTQATVYVRKVIDKKRMIKESAPEFSVSGSDVEDEKEEPKLDGEKDPDFSQTEGGAKRQKLNDTVSLPTAVVTTTSKSGIRRSTRHRKLRGEKALIVSANQTLKDLKIQIMHAFSVAPFDQNLSIDGRCLKDDSATLGSLGVIPESIICLKADEPIADYAAMDDVYQVCMPEEGFKGTGLLGH", "length": 1047, "header": "sp|A0A0R4IB93-1|UBP48_DANRE Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 48 OS=Danio rerio OX=7955 GN=usp48 PE=3 SV=1 CANONICAL=A0A0R4IB93-1" }, "isoforms": [ { "isoform_ac": "A0A0R4IB93-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93/entry#A0A0R4IB93-1", "sequence": { "sequence": "MAPRLQLEKAAWRWAEAVRPEDITHEHIELAYRIAVSACKRGACRRNCKGNPNCLVGIGEQSWLGEIDENTFHNIDDPNSERRDKNTFVGLTNLGATCYVNTFLQVWFHNLELRRALYRFQNSRAEGHNTDSDYEPRTICEHLQYLFALLQNSNRRYIDPSGLVKALGLDTGQQQDAQEFSKLFLSLLEDTLSKQKDPNLQNVIQQQFCGQFSYVTVCNKCGRESPLPSRFYELELNIQGHKNLTECVTEFLKEEKLDGDNRYYCESCQSKQNATRRIKLQSLPRTLNFQLMRFVFDRQSGHKKKLNTFISFPEVLDMEPFLEGREEKCTYELSAVLIHRGVSAYSGHYIAHVRDAHTNDWYKFNDEEIEKMEGKKLQLGIEEDIAETAKSQTRKPKCSKGYHCSRNAYMLVYKQQTEEINQTESPVDVPAFLQKLVEQDNRKFEEWCSEMSDMRKQSVDKGKAKHEEVKELYELLPAEDGQSYEFVPLEWLKKWLDDSTAIKEIDNSQFLCTHGKLHPDKIGEAKRISLKAADLLFSRYGGGPRLDRSSLCRDCVTQRCRVIRLKNQLNEDYREVTNLAKSALKSEESGFWIGKASLRSWRQLALDQLEEDEEETKHNNSKINGEKSSPGTKADGVKGDSEDGDGEEMKNFNEDILCYHGGLSILENDRRLVSAEVWNKLRMYFPKAPEFTQDHDPCQQCMRLEREGKENEALNRMMANEQKSSLLNLFQEKNRPTLQKWPQDTDILYIVPLYFVEEWKKFIRRPAKGNPVSNVGNSILLCPHGGFMFTYDSMLQGDAQHIALLWPAEWEVISKMFLVDQVISICRIHDKTQDNGNVQYQTHPDLCRECREGFIFQQQRDMREYTQATVYVRKVIDKKRMIKESAPEFSVSGSDVEDEKEEPKLDGEKDPDFSQTEGGAKRQKLNDTVSLPTAVVTTTSKSGIRRSTRHRKLRGEKALIVSANQTLKDLKIQIMHAFSVAPFDQNLSIDGRCLKDDSATLGSLGVIPESIICLKADEPIADYAAMDDVYQVCMPEEGFKGTGLLGH", "length": 1047, "header": "sp|A0A0R4IB93-1|UBP48_DANRE Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 48 OS=Danio rerio OX=7955 GN=usp48 PE=3 SV=1 CANONICAL=A0A0R4IB93-1" }, "locus": {} }, { "isoform_ac": "A0AB13AAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IB93/entry#A0AB13AAA7-1", "sequence": { "sequence": "MAPRLQLEKAAWRWAEAVRPEDITHEHIELAYRIAVSACKRGACRRNCKGNPNCLVGIGEQSWLGEIDENTFHNIDDPNSERRDKNTFVGLTNLGATCYVNTFLQVWFHNLELRRALYRFQNSRAEGHNTDSDYEPRTICEHLQYLFALLQNSNRRYIDPSGLVKALGLDTGQQQDAQEFSKLFLSLLEDTLSKQKDPNLQNVIQQQFCGQFSYVTVCNKCGRESPLPSRFYELELNIQGHKNLTECVTEFLKEEKLDGDNRYYCESCQSKQNATRRIKLQSLPRTLNFQLMRFVFDRQSGHKKKLNTFISFPEVLDMEPFLEGREEKCTYELSAVLIHRGVSAYSGHYIAHVRDAHTNDWYKFNDEEIEKMEGKKLQLGIEEDIAETAKSQTRKPKCSKGYHCSRNAYMLVYKQQTEEINQTESPVDVPAFLQKLVEQDNRKFEEWCSEMSDMRKQSVDKGKAKHEEVKELYELLPAEDGQSYEFVPLEWLKKWLDDSTAIKEIDNSQFLCTHGKLHPDKIGEAKRISLKAADLLFSRYGGGPRLDRSSLCRDCVTQRCRVIRLKNQLNEDYREVTNLAKSALKSEESGFWIGKASLRSWRQLALDQLEEDEEETKHNNSKINGEKSSPGTKADGVKGDSEDGDGEEMKNFNEDILCYHGGLSILENDRRLVSAEVWNKLRMYFPKAPEFTQDHDPCQQCMRLEREGKENEALNRMMANEQKSSLLNLFQEKNRPTLQKWPQDTDILYIVPLYFVEEWKKFIRRPAKGNPVSNVGNSILLCPHGGFMFTYDSMLQGDAQHIALLWPAEWEVISKMFLVDQVISICRIHDKTQDNGNVQYQTHPDLCRECREGFIFQQQRDMREYTQATVYVRKVIDKKRMIKESAPEFSVSGSDVEDEKEEPKLDGEKDPDFSQTEGGAKRQKLNDTVSLPTAVVTTTSKSGIRRSTRHRKLRGEKALIVSANQTLKDLKIQIMHAFSVAPFDQNLSIDGRCLKDDSATLGSLGVIPESIICLKADEPIADYAAMDDVYQVCMPEEGFKGTGLLGH", "length": 1047, "header": "tr|A0AB13AAA7-1|UBP48_DANRE Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 48 OS=Danio rerio OX=7955 GN=usp48 PE=3 SV=1 CANONICAL=A0A0R4IB93-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development.", "journal": "BMC Genomics", "date": "2009", "authors": "Tse William K F, Eisenhaber Birgit, Ho Steven H K, Ng Qimei, Eisenhaber Frank, Jiang Yun-Jin", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "20040115", "url": "https://glygen.org/publication/PubMed/20040115" } ] }, { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Importance of deubiquitinases in zebrafish craniofacial development.", "journal": "Biochem. Biophys. Res. Commun.", "date": "2017", "authors": "Tse William Ka Fai", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "28450118", "url": "https://glygen.org/publication/PubMed/28450118" } ] }, { "title": "Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish.", "journal": "Genetics", "date": "2019", "authors": "Kossack Michelle E, High Samantha K, Hopton Rachel E, Yan Yi-Lin, Postlethwait John H, Draper Bruce W", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "30446521", "url": "https://glygen.org/publication/PubMed/30446521" } ] }, { "title": "Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss.", "journal": "Hum. Mol. Genet.", "date": "2021", "authors": "Bassani Sissy, van Beelen Edward, Rossel Mireille, Voisin Norine, Morgan Anna, Arribat Yoan, Chatron Nicolas, Chrast Jacqueline, Cocca Massimiliano, Delprat Benjamin, Faletra Flavio, Giannuzzi Giuliana, Guex Nicolas, Machavoine Roxane, Pradervand Sylvain, Smits Jeroen J, van de Kamp Jiddeke M, Ziegler Alban, Amati Francesca, Marlin Sandrine, Kremer Hannie, Locher Heiko, Maurice Tangui, Gasparini Paolo, Girotto Giorgia, Reymond Alexandre", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAA7", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAA7" } ], "reference": [ { "type": "PubMed", "id": "34059922", "url": "https://glygen.org/publication/PubMed/34059922" } ] } ], "pathway": [ { "id": "dre:100332674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332674", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", 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