{ "uniprot_canonical_ac": "A0A0G2KB83-1", "uniprot_ac": "A0A0G2KB83", "uniprot_id": "A0A0G2KB83_RAT", "mass": { "chemical_mass": 61772.0, "monoisotopic_mass": 61772.0 }, "refseq": {}, "gene_names": [ { "name": "Ces2c-ps2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83", "id": "A0A0G2KB83" } ], "protein_names": [ { "name": "Carboxylic ester hydrolase", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83/entry#names_and_taxonomy", "id": "A0A0G2KB83" }, { "name": "3.1.1.-", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83/entry#names_and_taxonomy", "id": "A0A0G2KB83" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB83", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Ces2c-ps2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83", "locus": { "chromosome": "19", "start_pos": 99434, "end_pos": 115117, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000052151", "url": "https://www.ensembl.org/id/ENSRNOG00000052151" } ] } } ], "crossref": [ { "id": "RGD:1561236", "url": "https://alliancegenome.org/gene/RGD:1561236", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2KB83", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2KB83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000052151", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000052151", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RDSADWP", "url": "https://omabrowser.org/oma/group/RDSADWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1561236", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1561236", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2KB83", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VQGKLIHVKDTKAGVHTFLGIPFAKPPVGPLHFAPPEVPEPWSGVRDATSHPAMCLQNLELLYPEGMKEMKLNLFPFSMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGGLVAGMASMYDGSTLAATEDVVVVTIQYHLGVLGFFSTGDQHARGNWGYLDQVATLRWVQQNIAHFGGNPNRVTIFGESSGGTSVSSHVVSPMSQGLFHGTIMESGVTLLPCLFSNTSETVSTTVSKISGCEAMDSEALVHCLRGKSEAEILAINKVFVLIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNNDEYGWTIPRLTGSAQTIKEITRENLKAVLKNTTAELLLPRDCSDLLMEEYMGDIEDPQTLQAQFTEMMEDFIFAIPALQVAHFQSSHAPVYFYEFQHQSSFFKGIRPPHVKADHADEVPFVFGCMLFGMKRIQLEACVSLGHWLMKKGEAAEPMKYWANFARNGNPNSEGLPYWPMLNQDEQYMQLDIQTAVGRALKARRLKFWTETLPQKIQELNRSVHTKICNSVLDTVMLPEVAPPAAIAAFLLFPDFKWS", "length": 557, "header": "tr|A0A0G2KB83-1|A0A0G2KB83_RAT Isoform 1 of Carboxylic ester hydrolase OS=Rattus norvegicus OX=10116 GN=Ces2c-ps2 PE=3 SV=2 CANONICAL=A0A0G2KB83-1" }, "isoforms": [ { "isoform_ac": "A0A0G2KB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83/entry#A0A0G2KB83-1", "sequence": { "sequence": "VQGKLIHVKDTKAGVHTFLGIPFAKPPVGPLHFAPPEVPEPWSGVRDATSHPAMCLQNLELLYPEGMKEMKLNLFPFSMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGGLVAGMASMYDGSTLAATEDVVVVTIQYHLGVLGFFSTGDQHARGNWGYLDQVATLRWVQQNIAHFGGNPNRVTIFGESSGGTSVSSHVVSPMSQGLFHGTIMESGVTLLPCLFSNTSETVSTTVSKISGCEAMDSEALVHCLRGKSEAEILAINKVFVLIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNNDEYGWTIPRLTGSAQTIKEITRENLKAVLKNTTAELLLPRDCSDLLMEEYMGDIEDPQTLQAQFTEMMEDFIFAIPALQVAHFQSSHAPVYFYEFQHQSSFFKGIRPPHVKADHADEVPFVFGCMLFGMKRIQLEACVSLGHWLMKKGEAAEPMKYWANFARNGNPNSEGLPYWPMLNQDEQYMQLDIQTAVGRALKARRLKFWTETLPQKIQELNRSVHTKICNSVLDTVMLPEVAPPAAIAAFLLFPDFKWS", "length": 557, "header": "tr|A0A0G2KB83-1|A0A0G2KB83_RAT Isoform 1 of Carboxylic ester hydrolase OS=Rattus norvegicus OX=10116 GN=Ces2c-ps2 PE=3 SV=2 CANONICAL=A0A0G2KB83-1" }, "locus": { "chromosome": "19", "start_pos": 107493, "end_pos": 99437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000077592.2", "url": "https://www.ensembl.org/id/ENSRNOT00000077592.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075691.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075691.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PCX7-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "si:dkey-30c15.17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSSCTTSILLALLSMTVVLNGREERKPQQKSFNVDTEYRTMMFNIPNIEHNRKHEIALDDTFLEESLNLIKSLEFYGNADDTGLVESTPDSTNIVHKDPEIDITVHDAANKAESILNSLNNTSSDGLEDGSGADPVVVTLLGRVRGLTLEKAHVFYGIPYADPPVGDKRWAPPSPVSPWLYTYNATFPRPACMQMCAGEFSRLCPPEVSEDCLYLNVFVPVSVNLSLPKVTALPVMVWIHGGDFIAGSASKPLYDGRYISNYSNTVVVNMEYRLGAFGFLVTGKDPESSAVGNYGILDQQAALHWVQENIAAFGGDPNKVTLFGESAGAQSVSLHLMMQSSETLFRHAAIQSLPFSLPLKTRWDAMKLGWDFAKLTNCSVFDLPCMRSLSSEDVLNAQIKSGSKIINPFRFLEVFETWGPFIDGQLLKEQPITAFQKGHWQSYKPVILGTTSEEGVMFVYRNFNKSVSMLECVLYTAAIFKQHALKILHKYIPFYRNQDRRVMLSQMVTDYVFSCPARQSARSGVKVGGAVWMYVFDHAPSDPNIWAELTFCYNHSCHGAELPFLFDSAPSTNFTFTPQERLLANRMACYWGMFAHTGDPNSRDEQTHFCREQRLPVWPRYTDIGGWTILNLTLQSHPQHGSRDHFCDFWDRLDIY", "length": 657 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PZ17-1", "protein_name": "Uncharacterized protein ces2b", "gene_name": "ces2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMRESAVLSLCILIAVTLQNSVKAEDGPILQTNSGALKGLQMKARGKDTVIHSYLGIPFAKPPVGPLRLAPPQPAEKWEGVRDATKQPLMCLQDRQLVEDLVANLSAKVDMVDSSEDCLYLNVYTPSKPGRNDKLPVMVWIHGGGFTTCSASLFDGHVLAAYQDVVVVVIQYRLGLLGFFSTGDENAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNVNPLPIAQAIGNASGCDISSTKKIVDCLMQKSEVEILKITMENPLFRFGVTIDGQFLPRPAAELFQSQQFNKVPLMTGVTDDEIGFVLPNYLLPPDWINGLDLESILPLLTVFNPALQDQSVLELLLNEYLGTSPDRIRIRDGFREMLGDFMFNIPARQTASYHRDAGAPVYVYEFRHPPSVLQRKRPSFSGSDHGDEIVFVFGYCFSEGPIGMAENLSDEEDELCRTTMAYWGNFAHTGNPNGPGLTSWPEFGDEAEYLSIGLDPKASTDLKGKHFTFVTQTFPRILSERKEGPVVNTKLGSLRGSYMMAKGKDSVISSYFAIPFAKSPVGPLRLTPPQPADAWQGVRDATKQPPMCLQPKEVMVDLLATMPLKTEFPEVSEDCLYLNIYTPSKPGDNKKLPVMVWIHGGGLAFGSASIFDAHALAAYQDIVVVMVQYRLGLLGFFSTGDEHAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTVFGESAGGVSASLLVLSPLSANLFHRAIAESGTAAMNAIMSPDPLSTARSLGNVSGCDISSTKKIVDCVMQMTEEDILKIAREQVLLRFGVTVDGQFLPKSVDELLQSQEFSKVPLMTGVTDDDGGFTLPEFIAPPGWRDGMTKDQIMPFLPTYNYDLQDPGLAEIVLKEYLGATTDKIKIRDGFREIVGDFFFNLPARKLANYHRDTGAPVYMYEFQHPAYIFQNKRPSFVGCDHGDELLFVFGYCFGNGHIKVEGELSKEEQELCKTTMAYWGNFARTGNPNGPGLVEWPKYGAEAEYLGIGLEQKSSKNFKGNHFHFMIEKLPQIIKEWKEGPVVETKLGSLRGAFLTVKGKDTIVNSYLGVPFAKPPVGPLRLARPQAAEKWQGVRDATKQPRMCLQERQMTVTELEFLSMDVEVPEVSEDCLYLNIYTPVKPGQGDKKLPVMVWIHGGGLSLGSASMYDGSVLAAYQDVVVVLIQYRLGLLGFLSTGDEHAPGNYGFLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSTLILSPLASGLFHRAIAESGTAFWDGLVMADPFQRAQTAAKQCNCDSSSSAKIVDCIMHWSEEEALECAKKFQMMHFSVAVDSYFLPKPIEEIVEKQEFSKVPLINGINNDEFGFLLAEYFLGPEWMNGLKREQIAEALTLTYPDPKDRWIIDLVAKEYLGDTHDPIEIREVYREMMGDVLFNIPALQLAKHHSGTGAPVYLYELQHPPSFLQKKRPSFVGVDHADDLYFIQGTCFAKAHLRISAPFTEEENELCRTVMAYWGNFAHTGSPNGPGLTHWPEYENENEYLAIGLQQKPGKNLKHKHYEFMTKTLPELIRQGKTKHSEL", "length": 1611 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "RGD:1561236", "url": "https://alliancegenome.org/gene/RGD:1561236#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1ZA98-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Jhe", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIQQRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEIRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLWSHILNEK", "length": 579 }, "evidence": [ { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "RGD:1561236", "url": "https://alliancegenome.org/gene/RGD:1561236#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3Z298-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLYALILLSLSAMAWGGYPSSPPVVNTTHGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGASAYDGRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKTTTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVLPKAPEAILAEKNFNTVPYIVGINKQEFGWTLPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRGHRDAGAPTYMYEFQSRPSFSSELKPKTVTGDHGDEVYSVFGAPILREGSSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYNQKKGYLQIGATTQQAQGLKDKEVSLWTELRAKKPPQTGHTEL", "length": 562 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z5G7-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLHALVWASLALCPIWGHSPSSPVVDTTQGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGGASLYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLVACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMSTVIDGVVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKMNEETASLLLRRFHSDLNISESLIPAVIEKYLRGTDDPAKKRDLLLDMFSDVFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFSVFGIPLLKEGTSEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEKEGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEHREHK", "length": 567 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZP14-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2j", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLARLPDWLYVVACGFLLLLQHVHGQDSASPIRNTHTGQVRGSFVHVKDTKSGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQTAMMNLEGMKETELTKLPMSEDCLYLNIYVPAHAHEDSNLPVMVWIHGGGLVGGSASMNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQHARGNWGYLDQMAALRWVQQNIAYFGGNRDSVTIFGVSAGGTSVSSHVVSPMSKGLFHRAIMQSGVALLPGLISDTSEVVYKTVANLSGCEASDSEALIRCLRAKSKQEILAINQVFKMIPGVVDGKFLPKHPQELLASKDFHPVPSIIGVNTDECGWGVPTILGLYHIINNITRETLPAALKIAAAQMMLPPECIDLIMEEYMGDTEDAETLQAQFKEMLGDFIFVIPALQVAHFQRSQAPVYFYEFQHLLSFIKQVRPFYPKADHGDDTVFVFGSYFWGMTFDLTEEEELLKRRVMKYWANFARTGNPNGEDLPHWPVLDHDEQYLQLNSQPAVGRALKARRLQFWTKTLPQKIQELKGSQSKHAEL", "length": 556 }, "evidence": [ { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AA05-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIRPLDCTWMGVVTRPHNVRRVMQSPSEEHRDPVTGPQSNWPSTMWLFALALTSLNTYMAFGHPSSPPVVDTLQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPPMCSQITGVGPVLSEVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTFDGLALSTHEKVVVVVIQYRLGIWGFLSTGDEHSRGNWGHFDQVAALQWVQNNIVNFGGDPNSVTLFGESAGGESVSVLVLSPLTKNLFHRAISESGVALTPCLFRENTRLAAEQVAIATGCAATTSADIVRCLREKTEEELLATTLKMKFFALDLHGDPRESYPFLTTVIDGVLLPKAPEEILSEKNFNTVPYIVGINKQEFGWFIPTMMGYPLSESKLDQKTATSLLWKSYPLTNISKELTPVATEKYLGGSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHRDARATTYVYEFKYHPSFVSDMRPKTVIADHGDEVYSVWGTPFLKEGASEEEINLSTMMMKFWGNFARNGNPNGEGLPHWPEYDEKESYLQIGTTIQQAQKLKYKEVAFWTGLRGMEVEEATEEDTQK", "length": 607 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AE76-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAGWSMKWTLDLSLTLWLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKIMVKCLKALPAEKVMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVFPEDPVVLLTRGQVKPVPYLLGVNSAEFEWSLPFLMKLQLNQRIMNKNYITKLLWSCSILLNITEEQIPLVAREYLSDAISHHDWKMFRNHLIDLVGDATFVYATLQAARYHRDAGSPVYLYEFKHHAPGIIVKPRSDGADHGDELSYLFGSPFSKGSSRGEEKEFSLQMMKYWANFAHTGDPNDRELPYWPRFDKEEKYLQLDFDTRVGVKLREKQMTFWRRLRQPQKP", "length": 563 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PV38-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRNQMHSWLDAVFFGLLLLLGHVQGHDSPETSPIRSTHSGQVQGRLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAICPQNVTMNMEGLKELKLTLPPVSMSEDCLYLNIYTPAHAQEGSNLPVMVWIHGGALTVGMASMYDGSVLAATEDVVVVAIQYRLGVLGFFSTGDEHARGNWGFLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVALLPGTIFSFSEVVYQTVAKLSGCEAMDSEALVRCLRGKSEEEILAISKNFQMIPGVVDGEFLPKHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGSTQTIKGITRENLQAVLKDTAPQMMLPPECSDLLMEEYMEDIEDPKTLQIQFTEMMEDFMFVIPSLQVAYFQRSHAPVYFYEFQHQSSFLKDVRPPHVNADHGDEVPFVFGSFFWGMKLNLTEEEKLLNRRMMKYWANFARHGNPNSESLPYWPVFDHDEQYLQLNIQPAVGQFQKARKLQFWTKTLPRKIEELKRSQNVHKEL", "length": 560 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PYP1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLFALALASLNTCMALGHLSSPPVVDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWSSVKNTTSYPPMCSQITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTFDGLALSTHENVVIVVIQYRLGIWGFLSTGDEHSRGNWGHLDQVAALQWVQNNIANFGGDPSSVTLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTPCLFRETTRRAAEQVAIATGCVATTSADIVHCLREKTEEELLATTLKMKFFALDLLGDPRESYPFLTTVIDGVVLPKAPEEILAEKSFNTVPYIVGINKQEFGWFIPMMMGYPLSEGKLDQKSATSLLWKSYPLTNISKELTPVATEKYLGGSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHRDAGAPTYMYEFKYHPSFVSDMRPKTVIADHGDEVYSVWGTPFLKEGASEEEINLSTMMMKFWGNFARNGNPNGEGLPHWPEYGEKESYLQIGATTQQAQRLKDKEVAFWTSLRAMEVGEATKGDTQR", "length": 563 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6Z9B9-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLEQIHARLTTATCGLLLLLRVQGQDSTSPIRTTHTGQILGSLIHMKDLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDGSMLAAMENVVVVTIQYRLGVLGFFSTGDERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQTVANLSGCEQVDSEALVNCLRGKSEEEIMAINKAFKIIPGIVDGIFLPRHPQELMASADFHPVPSIIGVNNDEYGWIIPSSMSMIDSKKGMDRQMVQAILQRRATQMMWPPEVSDLLMEEYMGDNEDPQFLQVQFKEMMKDFTFVIPALQVAQFQRSHAPVFFYEFQHRPSFFKDSKPSHVKADHGDEILFIFRSFWGGTQVDFTEEEELLSRRMMKYWANFARQRNPNSEGLPYWPMFDQDEQYLQLDTQPAVGRALKTRRLQFWTKTLPEKIQELKDIEDRHKEL", "length": 558 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V7J5-1", "protein_name": "Pyrethroid hydrolase Ces2e", "gene_name": "Ces2e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQTRAWKSIMPLESLPGWLNAVVWGLLLLFCQVQGQDSASPIRNTHTGQVRGSFVHVKDTKSGVHTFLGIPFAKPPIGPLRFAPPEPPEPWSGVRDGTSHPAMCLQNIDGLNLENLKIKMSRSPVSMSEDCLYLSIYTPAHTHKDSNLPVMVWIHGGGLCWGMASTYDGSMLAAIEDVVVVTIQYRLGILGFFSTGDEHARGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIYTMVANLSGCEPVDSEALMSCLREKSEEEMLAINNIVRTISGVVDGKFLPRHPLELLASVDFHPVPSIIGINSDEYGWIIPMLHPDSTMKEINRETMRAVLKNTAVQMMLPPECSDLLMEEYMGDTEDSKTLQIQFNEMMGDFIFVIPALQVAHFQRSHAPVYFYEFQHQSNFLKDIRPPHVKADHGDELPYVIGYLFWDMKFVFTEEEKLLSRKMIKYWANFARHGNPNSEGLPYWPALDHDEQYLQLDIQPVVGRALKARRLKFWTKTLPQKIQELKGSQDNHTEL", "length": 567 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9W7-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQNQLHSWLNAVFFGLLLLLIHVQGQHSPESSPIRNTHIGQVRGKLDHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNLDVINAEGLKEMKLKLPPVSMSEDCLYLNIYAPAHAHEGSNLPVMVWIHGGGLMTGMASMYDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTCVSTHVVSPMSQGLFHGAIMESGVALLPYLIADTSEMFSTMVAKVSGCEAMDSEALVHCLRAKSEAEILAINKVGRIMVPAVVDGEFLPRHPKELLASEDFRPVPSIIGVNNDEYGWTIPLVMGTTQMIKELSRENLQAILKKTTAQLMLPLECSDLLMEEYMGDIEDPKTLQAQFTELMEDFMFVIPALQVAHFQCSHAPVYFYEFQHQITFLKDIRPPHVKADHGDEIPFVFGYFFWDMKTDFTEEEKLLSRRMMKYWANFARHGNPNSEGLSYWPVMDHDQQYLQLDTQPAVGRALKARRLQFWTKTLPQKIQELKGAQDNHTEL", "length": 562 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00748-1", "protein_name": "Cocaine esterase", "gene_name": "CES2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL", "length": 559 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" }, { "id": "RGD:1561236", "url": "https://alliancegenome.org/gene/RGD:1561236#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70631-1", "protein_name": "Acylcarnitine hydrolase", "gene_name": "Ces2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10959-1", "protein_name": "Carboxylesterase 1C", "gene_name": "Ces1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCALVWASLAVCPIWGHPSSPPVVDTTKGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNTTTYPPMCSQDGVVGKLLADMLSTGKESIPLEFSEDCLYLNIYSPADLTKNSRLPVMVWIHGGGLIIGGASPYSGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESAGGVSVSALVLSPLAKNLFHRAISESGVVLTTNLDKKNTQAVAQMIATLSGCNNTSSAAMVQCLRQKTEAELLELTVKLDNTSMSTVIDGVVLPKTPEEILTEKSFNTVPYIVGFNKQEFGWIIPTMMGNLLSEGRMNEKMASSFLKRFSPNLNISESVIPAIIEKYLRGTDDPAKKKELLLDMFSDVFFGIPAVLMSRSLRDAGAPTYMYEFQYRPSFVSDQRPQTVQGDHGDEIFSVFGTPFLKEGASEEETNLSKLVMKFWANFARNGNPNGEGLPHWPKYDQKEGYLQIGATTQQAQKLKGEEVAFWTELLAKNPPQTEHTEHT", "length": 549 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16303-1", "protein_name": "Carboxylesterase 1D", "gene_name": "Ces1d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLYPLVWLFLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGQVLSAHENVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIANLIATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKTPEEILAEKSFNTVPYIVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLLWKSYPTLKISEKMIPVVAEKYFGGTDDPAKRKDLFQDLVADVMFGVPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGDHGDELFSVFGSPFLKDGASEEETNLSKMVMKYWANFARNGNPNGGGLPHWPEYDQKEGYLKIGASTQAAQRLKDKEVAFWSELRAKEAAEEPSHWKHVEL", "length": 565 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P18167-1", "protein_name": "Esterase P", "gene_name": "Est-P", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIFKRLLCLTLLWIAALESEADPLIVEITNGKIRGKDNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYRTGIRPDEEVISKKFIGMLEDFALNDKGTLTFGECNFQNNVNSKEYQVLRISRNACKNEEYARFP", "length": 544 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P23141-1", "protein_name": "Liver carboxylesterase 1", "gene_name": "CES1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL", "length": 567 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23953-1", "protein_name": "Carboxylesterase 1C", "gene_name": "Ces1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLHALVWASLAVCPILGHSLLPPVVDTTQGKVLGKYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGASPYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKKNIQAVNEIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLVQYNISLSTMIDGVVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWIIPMMLQNLLPEGKMNEETASLLLRRFHSELNISESMIPAVIEQYLRGVDDPAKKSELILDMFGDIFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFFVFGAPLLKEGASEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEQEGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEHTEHK", "length": 554 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08BF1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "ces2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIKDVLLCLCLTLAPVWSAPVQEDSGPVAVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEHPLMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPVMIWIHGGGLAMGGACMFKELCLYDGTPLAAYEKVVVVVIQYRLGILGYFSTGDQHAKGNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYFVKDPSTHAQVIANITECDFSSSEVLVKCIREMTEEQIIKAAQKKGIFPGAAVDGEFIKAQPEEILKSKDFQKVPILIGTTNHEFGWMLPQIFLPKEWVKGMDTKAAKDRLGLLNADGASGANGIIADEYFKNAKTPEEIRDAFTELLGDIFMVIPSITVASYHREAGVPVYMYEFQHGPSTANKFRPSFVKADHADDVGFVFGACFWDVHVKGLGTLTEEENQLCRTVMKYRANFIRTGSPNPAPVPWPVYDQSNKYLNLGLQQTEGQDLKKDKLLFFTEELPKKLAAPPTA", "length": 555 }, "evidence": [ { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" }, { "id": "RGD:1561236", "url": "https://alliancegenome.org/gene/RGD:1561236#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08ED5-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVHRLPGWLDAAACGLLVLLLHVKGLDSSEASPIRNTHTGQVRGKFVHLTDIKAGAHNFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNDDIVNLEGLKIIKMILPPFSMSEDCLYLNIYTPAHAQEGSNLPVMVWLHGGGLVAGMASMYDGSVLAATEDVVVVVTQYRLGIPGFYSTGDEQARGNWGFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSPVSQGLFHRAIMESGVALLPTIIPDSPEMIFTKVANLSGCETSNSEALVRCLRGKSEAEILAMSKAFRFMPAVVDGKFLPRHPKKLLASADFHPVPSIIGVNNDEYGWIIPKIFKFSQTIRKINRNNLKAIMKITTEQMMLPSECGDLLIEEYLRDTEDPWTLQMQFREMIGDFLIIIPALQVARFQRSHAPVYFYEFQHRSSLLKYFRPWHVKADHGDELYLIFGSFFWGLKFSFTAEEKLLSRKMMKYWANFARYGNPNSEDLPYWPASNQDDLYLQLDIHPSVGHALKARRLPFWTKTLPQKMLELKGNHDKIKAV", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q32Q55-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2h", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKQIHARLTTAACGLLLLLQVQGQDSLSPIRTTHTGQILGSLIHMKGLDVGVHSFLGIPFAKPPIGPLRFAPPEAPEPWSGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPLIPMSEDCLYLNIYTPNHAHEGSNLPVMVWIHGGALVIGMASLYDGSMLAAMENVVVVTIQYRLGVLGFFSTGDQHARGNWGYLDQVAALHWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSRGLFHGAIMESGVALMSSLISVSSDVVYRTVANLSGCEQVDSKALVNCLRGKSEEEIMSINKAFRIISGIVDGIFLPRHPKELLASADFHPIPSIIGVNNDEYGWIIPSSMTTTDSKKKMDRQMVQAILQKRVAQMMWPPEFSDLLLEEYMGDSEDPQFLQVQFKEMMEDFTFVIPALQVAHFQRSNAPVYFYEFQHRPSFFKDSKPPHVKADHGDEILFIFRSFWGGTQVDLTEEEELLSRRMMKYWANFARQGNPNSEGLPYWPVFDHDEQYLQLDTQPAVGRALKAKRLQFWTKTLPEKIRELKDTEDRHTEL", "length": 558 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GRG2-1", "protein_name": "Carboxylesterase 5A", "gene_name": "Ces5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDWVHTGQALIWVLWIFAAIIRGSVTEEPHRYTRLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQNLEWLFIYQNLLKVHYPKLGVSEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSASIFDGSALAAYEDVLIVTIQYRLGIFGFFNTQNQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCNVSDSKVLLKCLREKSSLELLSLGQKTKAFTRVVDGSFFPEEPMELLSQKTFKTVPSIIGVNNQECGYILPMREAPEILFGSNESTALTLIHVLLHIPPQYMHIVAKDYFHGKHSLTDIRDTLLDLFGDVFFVVPGLVTARNHRDADGPVYFYEFQHRPNCFQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDDLPLWPAYDQNESYLKLDVNISTGWRLKDRRVEFWTDTLPLIMSASKALLSPTFPLILFSLLPPSLLSIAS", "length": 575 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XG92-1", "protein_name": "Carboxylesterase 4A", "gene_name": "CES4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLYQSQRPEKQRQF", "length": 561 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63108-1", "protein_name": "Carboxylesterase 1E", "gene_name": "Ces1e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLYALILVFLAAFTAGGHPSSLPVVDTLQGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDPVAGQIVNDLLTNWEENISLQFSEDCLYLNIYTPADLTKRDRLPVMVWIHGGGLVLGGASTYDGLALSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIDNFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHKAISESGVALTAGLVKKNTRPLAEKIAVVSGCKSTTSASMVHCLRQKTEEELLETTLKLNLFSLDLHGDSRQSYPFVPTVLDGVVLPKMPEEILAEKDFNTVPYIVGINKQEFGWILPTMMNYPPSDMKLDPMTATSLLKKSSFLLNLPEEAIPVAVEKYLRHTDDPDRNKDQLLELIGDVIFGVPSVIVSRGHRDAGARTYMYEFQYRPSFSSKMKPSTVVGDHGDEIYSVFGAPILRGGTSKEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWSELLAMKPLHAGHTEL", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63880-1", "protein_name": "Carboxylesterase 3A", "gene_name": "Ces3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNMETTAQAGSSVRVWMACLLLIFPTTVIGPKVTQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPLGPLRFSAPLPPQPWEGVRDASINPPMCLQDVERMSNSRFTLNEKMKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLLVGSSTSHDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGIIVSSLLLSPMSAGLFHRAISQSGVVISKILEDLNAWSEAQNFANSVACGSASPAELVQCLLQKEGKDLITKKNVNISYTVNDSFFPQRPQKLLANKQFPTVPYLLGVTNHEFGWLLLKFWNILDKMEHLSQEDLLENSRPLLAHMQLPPEIMPTVIDEYLDNGSDESATRYALQELLGDITLVIPTLIFSKYLQDAGCPVFLYEFQHTPSSFAKFKPAWVKADHSSENAFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLPPWPQLNQLEQYLEIGLEPRTGVKLKKGRLQFWTETLPRKIQEWHREQRSRKVPEEL", "length": 571 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64176-1", "protein_name": "Carboxylesterase 1E", "gene_name": "Ces1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLSALILVSLAAFTAGAGHPSSPPMVDTVQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQDPVTGQIVNDLLTNRKEKIPLQFSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLGGASTYDGLVLSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESGVALTAGLVKKNTRPLAEKIAVISGCKNTTSAAMVHCLRQKTEEELLGTTLKLNLFKLDLHGDSRQSHPFVPTVLDGVLLPKMPEEILAEKNFNTVPYIVGINKQEFGWILPTMMNYPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIEKYLRDKDYTGRNKDQLLELIGDVVFGVPSVIVSRGHRDAGAPTYMYEFQYSPSFSSEMKPDTVVGDHGDEIYSVFGAPILRGGTSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWTELLAKKQLPTEHTEL", "length": 562 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64573-1", "protein_name": "Liver carboxylesterase 1F", "gene_name": "Ces1f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLSFLFLVSLATCVVYGNPSSPPVVDTTKGKVLGKYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTKNSRLPVMVWIHGGGMTLGGASTYDGRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAKQIADMAGCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMGFVPADVELDKKMAITLLEKFASLYGIPEDIIPVAIEKYRKGSDDSIKIRDGILAFIGDVSFSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQRPKHVVGDHADDLYSVFGAPILRDGASEEEIKLSKMVMKFWANFARNGNPNGRGLPHWPQYDQKEEYLQIGATTQQSQRLKAEEVAFWTQLLAKRQPQPHHNEL", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AW46-1", "protein_name": "Carboxylesterase 5A", "gene_name": "Ces5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDWVRPGQALIWVIWIFGAIIEGSVTEEPHRYTKLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQNLEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSASIFDGSALAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDLQVVANVCDCNVSDSKALLKCLREKSSLELMSLSQKAKSFTRVVDGSFFSEEPLELLSQKTLKIVPSIIGVNNQECGYILPVRDTPEILLGSNESTALTLIHTLLHIPTQHLYIVTKEYFHGKHSPTDIRDTLLDLFGDVFFVVPGLVTARYHRDSGGPVYFYEFQHRPHCFQNSRPAFVKADHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGADLPPWPVYDENEQYLELDVNISTGRRLKDQRVEFWTDTLPLILSASKALLSPTFSLILLSLLSPVLLSAAS", "length": 575 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NT32-1", "protein_name": "Carboxylesterase 5A", "gene_name": "CES5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP", "length": 575 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PDB7-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRSQMHNWLDVLLFGLLLLLGHVQGQDSPEASPIRNTHTGQVRGSLVHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLGVMKEIKLKLPPVSTSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGGLVAGMASMYDGSLLAAIEDLVVVTIQYRLGVLGFFSTGDQHARGNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGCEAMDSEALVRCLRGKSEAEILAINKLVQMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGVNNDEFGWTIPVVMGSAQTIKEITRENLQAVLKNTTAQLMLPPECSDLLMEEYMGDTEDAQTLQIQFTEMMEDFMFVIPALQVAYFQRSHASVYFYEFQHQIASLKDVRPTHVKADHADEIPFVFGYFFWDMKLDFTEGEKLLSRRMMKYWANFARHGNPNSEGLPYWPVMDHDEQYLQLDTQPAVGRALKSRRLQFWTKTLSQKIQELRASQDKHTEL", "length": 556 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" }, { "id": "RGD:1561236", "url": "https://alliancegenome.org/gene/RGD:1561236#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWW8-1", "protein_name": "Carboxylesterase 3", "gene_name": "CES3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLPSKIQQWHQKQKNRKAQEDL", "length": 571 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BK48-1", "protein_name": "Pyrethroid hydrolase Ces2e", "gene_name": "Ces2e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLYKLLGWLNAVACGVLLLVLHVQGQDSASPIRNTHTGQVRGSLVHVKDTDIAVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSHPNMCLQNDNLMGSEDLKMMNLILPPISMSEDCLYLNIYVPAHAHEGSNLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVAIQYRLGVLGFFSTGDQHAKGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVHRIVANLSGCAAVNSETLMCCLRGKNEAEMLAINKVFKIIPGVVDGEFLPKHPQELMASKDFHPVPSIIGINNDEYGWILPTIMDPAQKIEEITRKTLPAVLKSTALKMMLPPECGDLLMEEYMGDTEDPETLQAQFREMKGDFMFVIPALQVAHFQRSHAPVYFYEFQHRPSFFKDFRPPYVKADHGDEIFLVFGYQFGNIKLPYTEEEEQLSRRIMKYWANFARHGNPNSEGLPYWPVMDHDEQYLQLDIQPSVGRALKARRLQFWTKTLPQKIQELKGSQERHKEL", "length": 559 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K3R0-1", "protein_name": "Pyrethroid hydrolase Ces2a", "gene_name": "Ces2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLARLPGWLYVVACGLLLLLQHVHGQDSASPIRNTHTGQVRGSFVHVKDTKSGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQTDIMNLDGIKEMKLTVHPTPMSEDCLYLNIYTPAHAREGSNLPVMVWIHGGGLVLGSASMNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQNARGNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHVVSPMSKGLFHGAIMQSGVALLPDLISDKSEVVYKTVANLSGCEAPDSEALIRCLRAKSKQEILAINQVFKMIPGVVDGKFLPKHPQELLASGDFHPVPSIIGINTDECGWGIPVFLGLDHIIKKITRETLPTVLKSTAAQMMLPPECIDLIMEEYMGDTENPETLQEQFRHMLGDFMFVIPALQVAHFQRSQAPVYFYEFQHLPSFIKQVRPSHVKADHGDDILFVFGSYLWGMTFDLTEEEELLKRRVMKYWANFARTGNPNGEDLPHWPVLDHDEQYLQLNTQPAVGRALKARRLQFWTKTLPQKIQELKGSQSKHAEL", "length": 558 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8QZR3-1", "protein_name": "Pyrethroid hydrolase Ces2a", "gene_name": "Ces2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLARLPGWLCVVACGLLLLLQHVHGQDSASPIRNTHRGQVRGSFVHVKDTKSGVHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQPDIMNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEGSNLPVMVWIHGGGLVVGSASMNDVSKLAATEEIVIVAIQYRLGVLGFFSTGDQHARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVYKTVANLSGCEATDSEALIHCLRAKSKQEILAINQVFKMIPAVVDGEFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDHIIKNITRETLPAVLKNTAARMMLPPECSHLLVEEYMGDTEDPETLQAQFREMLGDFMFVIPALQVAHFQRSQAPVYFYEFQHLSSFIKHVRPSHVKADHGDDVAFVFGSYLWDMNLDLTEEEELLKRMMMKYWANFARNGNPNSEGLPSWPVLDHDEQYLQLDTQPAVGRALKARRLQFWTKTLPQKIQELKGSQDKHAEL", "length": 558 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R0W5-1", "protein_name": "Carboxylesterase 4A", "gene_name": "Ces4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAGWNMKWILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVDGVVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLNDAISNHDWKMFRNRLIDLIGDATFVYATLQAARYHRDAGSPVYLYEFKHHASSGIIIKPYNGADHGDELSYLFGSPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPNGEKLPYWPRFDKDEKYLQLDFDTRVGVKLKEKKMAFWSQLRQSQKP", "length": 563 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCC2-1", "protein_name": "Liver carboxylesterase 1", "gene_name": "Ces1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCALSLISLTACLSLGHPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLVIDGASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALAGCKTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLFLDLIGDIMFGVPSVIVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELLGDHADELFSVWGAPFLKEGASEEEINLSKMVMKFWANFARNGNPNGEGLPHWPEYDQKEGYLQIGVPAQAAHRLKDKEVDFWTELRAKETAERSSHREHVEL", "length": 565 }, "evidence": [ { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCT4-1", "protein_name": "Carboxylesterase 1D", "gene_name": "Ces1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLYPLIWLSLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQEFGWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTLKISENMIPVVAEKYLGGTDDLTKKKDLFQDLMADVVFGVPSVIVSRSHRDAGASTYMYEFEYRPSFVSAMRPKAVIGDHGDEIFSVFGSPFLKDGASEEETNLSKMVMKFWANFARNGNPNGGGLPHWPEYDQKEGYLKIGASTQAAQRLKDKEVSFWAELRAKESAQRPSHREHVEL", "length": 565 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCU1-1", "protein_name": "Carboxylesterase 3B", "gene_name": "Ces3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNMRTMIPAGSSVLVWVTCLLLAFVTTVTGPKVIQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPVGPLRFSAPLPPQPWEGVRDASINPPMCLQDVEKMINSRFGLNEKIKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLLVGSSTSQDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGMIVSSLFLSPISAGLFHRAISQSGIVTTIMMEDMKPWPEAQNFANSVACGSASPAELVQCLLQKEGKDLIKQKNVNISYIVNDSFFPQRPEKLLADQQFPTVPYLLGVTNHEFGWLLLKSLNILDKLEHLSREDLLEISRPFLAIMEVPPEIMPTVIDEYLDNGSDQSATRYAFQELLGDISFIIPTLNFSKYLRDAGCPVFLYEFQHTPSSFAKFKPAWVKADHASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLPPWPQLNQLEQYLEIGLESRTGVKLKKGRLQFWTETLPRKIQEWHREQRSRKVPEEL", "length": 571 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91WG0-1", "protein_name": "Acylcarnitine hydrolase", "gene_name": "Ces2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRNQLHNWLNAGFFGLLLLLIHVQGQDSPEANPIRNTHTGQIQGSLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSFPMSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVIGMASMFDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDQHARGNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVALLPDLISETSEMVSTTVAKLSGCEAMDSQALVRCLRGKSEAEILAINKVFKMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSAQMIKGITRENLQAVLKDTAVQMMLPPECSDLLMEEYMGDTEDAQTLQIQFTEMMGDFMFVIPALQVAHFQRSHAPVYFYEFQHPPSYFKDVRPPHVKADHADEIPFVFASFFWGMKLDFTEEEELLSRRMMKYWANFARHGNPNSEGLPYWPVMDHDEQYLQLDIQPAVGRALKAGRLQFWTKTLPQKIQELKASQDKHREL", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041014-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-96#orthology", "database": "AGR" }, { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "FB:FBgn0010052", "url": "https://alliancegenome.org/gene/FB:FBgn0010052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91WU0-1", "protein_name": "Carboxylesterase 1F", "gene_name": "Ces1f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLSTLFLVSLATCVICGNPSSPPVVDTAHGKVLGKHVNVEGFSQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWSSVKNATTYPPMCSQDAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADFSKNSRLPVMVWIHGGGLKLGGASSFDGRALSAYENVVVVAIQYRLSIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMFTKDVRPITEQIAVTAGCKTTTSAVIVHCMRQKTEEELLEIMHKLNLYKLSLQGDTKNSDQFVTSVLDGVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMTGFLPADVKLDKKKAIALLEQFASMTGIPEDIIPVAVEKYTKGSDDPDQIREGVLDAMGDVAFGVPSVIVSRGHRDTGAPTYMYEYQYYPSFSSPQRPKNVVGDHADDVYSVFGAPILREGASEEEINLSKMVMKFWANFARNGNPNGKGLPHWPKYDQKEGYLHIGGTTQQAQRLKEEEVTFWTQSLAKKQPQPYHNEL", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKY3-1", "protein_name": "Putative inactive carboxylesterase 4", "gene_name": "CES1P1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLPALVLATLAASAAWAGHLSSPPLVDTLHGKVLGKFVSLEGFAQPVAVFLGIPFAKPPLGPLRFTLPQPAEPWNFVKNATSYPPMFTQDPKAGQLISELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSVGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEVGLRLVRLRLDTPTSLALCS", "length": 287 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIB1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "alpha-Est9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSMAAFDQFKIGLKMVDFKVQQRRYRTSEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKPLQKHFVFEMTDGSEDCLYLNVYTKNLYPTKPMPVMVWIYGGGFQFGEASRECYSPDYLLREDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWAVTPQRNWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTREYKCIERLVGLWTHFAACGNPNFDPEQEDLWQPVDPAAVEKHQLKCLNISDELKVIDVPDLKKLMVWESFFRRDELL", "length": 587 }, "evidence": [ { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" }, { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIB6-1", "protein_name": "carboxylesterase", "gene_name": "alpha-Est6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWKLCQPRSRSRIKCFRFLILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRLYSDLK", "length": 568 }, "evidence": [ { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIC3-1", "protein_name": "carboxylesterase", "gene_name": "alpha-Est1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEIRVGVGDLLKMGTKLIGHKIVQYRLGTKQTKVVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTYPRAKPMQKHFVLSIVEGSEDCLYLNVYSKRLRSDKPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWANEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFEGLFSYQSTLHDEEHMLSAFEVLIPREIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLHILSVKHFWHGIHRTVLARLSHAPATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQMCLNIGKQLEFIVLPESKQNRIWDRLYDKNDLF", "length": 565 }, "evidence": [ { "id": "HGNC:1864", "url": "https://alliancegenome.org/gene/HGNC:1864#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLA3-1", "protein_name": "FI17410p1", "gene_name": "Dmel\\CG4382", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWRLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFPLNWRRQTKEV", "length": 580 }, "evidence": [ { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VP25-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Est-Q", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRRGVYVMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAELEDCLTLSVYTKNLSASQPVMFYIYGGGFYNGSSEDHPPNYLLEKDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATASESFSPIVGDLHGILPQQPSELVKSYRRQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPLEGQDTQMSQKMVDVWTSFAIEGVPRNLSPLSSASGPYNKLNLEVTKGDDLLDTLTAAIDDPDNGRLQREDMEF", "length": 559 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y141-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "GH05741", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLMLFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMTDVSEDCLRLNVYTKDLKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFPLSSFH", "length": 550 }, "evidence": [ { "id": "MGI:2448547", "url": "https://alliancegenome.org/gene/MGI:2448547#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061013-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-99#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intracellular membrane-bounded organelle", "id": "GO:0043231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB83", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB83", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0G2KB83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 557, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2KB83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A0G2KB83" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 519, "end_pos": 521 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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