{ "uniprot_canonical_ac": "A0A0G2KA90-1", "uniprot_ac": "A0A0G2KA90", "uniprot_id": "A0A0G2KA90_RAT", "mass": { "chemical_mass": 100103.0, "monoisotopic_mass": 100103.0 }, "refseq": { "ac": "NP_001099631", "name": "desmocollin-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099631" }, "gene_names": [ { "name": "Dsc1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90", "id": "A0A0G2KA90" }, { "name": "Dsc1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099631", "id": "NP_001099631" } ], "protein_names": [ { "name": "Desmocollin 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90/entry#names_and_taxonomy", "id": "A0A0G2KA90" }, { "name": "desmocollin-1 precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099631", "id": "NP_001099631" } ], "function": [ { "annotation": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90#function" }, { "database": "UniProtKB", "id": "RU004358", "url": "https://www.uniprot.org/uniprotkb/RU004358#function" } ] } ], "disease": [ { "disease_id": "DOID:0050431", "recommended_name": { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "arrhythmogenic right ventricular cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle." }, "synonyms": [ { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "arrhythmogenic right ventricular dysplasia/cardiomyopathy", "description": "" }, { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "ARVC", "description": "" }, { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "ARVC cardiomyopathy", "description": "" }, { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "ARVD", "description": "" }, { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "arrhythmogenic right ventricular dysplasia", "description": "" }, { "id": "DOID:0050431", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050431", "name": "right ventricular ACM", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "arrhythmogenic right ventricular dysplasia 1", "description": "Any arrhythmogenic right ventricular cardiomyopathy in which the cause of the disease is a mutation in the TGFB3 gene." }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "ARVC1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "ARVD1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "TGFB3 arrhythmogenic right ventricular cardiomyopathy", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "arrhythmogenic right ventricular cardiomyopathy 1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "arrhythmogenic right ventricular cardiomyopathy caused by mutation in TGFB3", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "arrhythmogenic right ventricular dysplasia type 1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "arrhythmogenic right ventricular dysplasia, familial, type 1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "familial arrhythmogenic right ventricular dysplasia 1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "Uhl anomaly", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "arrhythmogenic right ventricular dysplasia, familial, 1", "description": "" }, { "id": "MONDO:0007152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007152", "name": "cardiomyopathy, right ventricular dilated", "description": "" }, { "id": "MIM:107970", "resource": "MIM", "url": "https://www.omim.org/entry/107970", "name": "Arrhythmogenic right ventricular dysplasia, familial, 1", "description": "Arrhythmogenic right ventricular dysplasia, familial, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050431" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Dsc1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90", "locus": { "chromosome": "18", "start_pos": 11502003, "end_pos": 11528494, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000056258", "url": "https://www.ensembl.org/id/ENSRNOG00000056258" } ] } } ], "crossref": [ { "id": "RGD:1310768", "url": "https://alliancegenome.org/gene/RGD:1310768", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2KA90", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2KA90", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000056258", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000056258", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "291759", "url": "https://www.ncbi.nlm.nih.gov/gene/291759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VTICRHE", "url": "https://omabrowser.org/oma/group/VTICRHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2KA90", "url": "https://www.orthodb.org/?gene=A0A0G2KA90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08758", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798695", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6805567", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6809371", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001099631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1310768", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310768", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KA90-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GE75", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GE75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8I6GE75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAACAAPGSTFSKQLLFLLLVLVLLCNACQKVSLQVPSHLKAEKPIGKVNLEECLKSPSLILSSDPAFRILEDGTIYATHDLLLSSEKRGFSILLSDSQGQEQKKLEIVLSAREKKAFRKRHTKEPVHKRSKRRWAPIPCSLMENSLGPFPQHVQRIQSDFSQNYSIFYSISGPGVDKEPFNLFYIEKDTGDIYCTRSIDREEYDQFMVYGYATTADGYAPEYPLPLLFKVEDDNDNAPYFETKLTVFSVPENCRYGTSVGQVTAIDKDEPGTLHTRLKYKILQQIPDHPKHFTVHPDTGVITTTTPLLDREKCDTYKLVMEVRDMGGQPFGLFTTGTITISLEDENDNSPCFTQSSYFAEVDENRIDVEILRMMVQDQDLPNTPHSKAVYKILQGNENGNFKITTDPNTNEGVLCVVKPLNYEVSRQVTLQISVLNEAQFTNAANTQPPTMCTATVTVKIKDRDEGPECLPPVKVIQSKDGLPAGQQLLGYKAMDPETSSGEGLRYKMVGDEDNWFEINESTGDLRTVKVLDRESKFVKNNQYNISVVAMDSVGRSCTGTLVVLLEDFNDHPPQIDKDITICQQEKDYAVLEPVDLDGPDNGPPFQFLLDNSSSKLWTLESQDGKRAILRQRHNLNYNYYSVPIQIQDRHGFSAKHVLSVRVCDCTIPSECRMAIEERDVKPNVILGKWAILAMVLGSALLLCILFTCFCVTTTKRTVKKCFPDDVAQQNLIVSNTEGPGEEVTEANIRLPTQTVNICDTSTSVGTLGGQGIKTQQNFEMVKGGYTLESNKGGGHHTLESSKGGVLGAADTGRYAYTDWQTFTQPRLGEKVYLCGQAEEHKHCDDYVRSYNYEGKGSMAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCVKK", "length": 896, "header": "tr|A0A0G2KA90-1|A0A0G2KA90_RAT Isoform 1 of Desmocollin 1 OS=Rattus norvegicus OX=10116 GN=Dsc1 PE=4 SV=2 CANONICAL=A0A0G2KA90-1" }, "isoforms": [ { "isoform_ac": "A0A0G2KA90-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90/entry#A0A0G2KA90-1", "sequence": { "sequence": "MAAACAAPGSTFSKQLLFLLLVLVLLCNACQKVSLQVPSHLKAEKPIGKVNLEECLKSPSLILSSDPAFRILEDGTIYATHDLLLSSEKRGFSILLSDSQGQEQKKLEIVLSAREKKAFRKRHTKEPVHKRSKRRWAPIPCSLMENSLGPFPQHVQRIQSDFSQNYSIFYSISGPGVDKEPFNLFYIEKDTGDIYCTRSIDREEYDQFMVYGYATTADGYAPEYPLPLLFKVEDDNDNAPYFETKLTVFSVPENCRYGTSVGQVTAIDKDEPGTLHTRLKYKILQQIPDHPKHFTVHPDTGVITTTTPLLDREKCDTYKLVMEVRDMGGQPFGLFTTGTITISLEDENDNSPCFTQSSYFAEVDENRIDVEILRMMVQDQDLPNTPHSKAVYKILQGNENGNFKITTDPNTNEGVLCVVKPLNYEVSRQVTLQISVLNEAQFTNAANTQPPTMCTATVTVKIKDRDEGPECLPPVKVIQSKDGLPAGQQLLGYKAMDPETSSGEGLRYKMVGDEDNWFEINESTGDLRTVKVLDRESKFVKNNQYNISVVAMDSVGRSCTGTLVVLLEDFNDHPPQIDKDITICQQEKDYAVLEPVDLDGPDNGPPFQFLLDNSSSKLWTLESQDGKRAILRQRHNLNYNYYSVPIQIQDRHGFSAKHVLSVRVCDCTIPSECRMAIEERDVKPNVILGKWAILAMVLGSALLLCILFTCFCVTTTKRTVKKCFPDDVAQQNLIVSNTEGPGEEVTEANIRLPTQTVNICDTSTSVGTLGGQGIKTQQNFEMVKGGYTLESNKGGGHHTLESSKGGVLGAADTGRYAYTDWQTFTQPRLGEKVYLCGQAEEHKHCDDYVRSYNYEGKGSMAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCVKK", "length": 896, "header": "tr|A0A0G2KA90-1|A0A0G2KA90_RAT Isoform 1 of Desmocollin 1 OS=Rattus norvegicus OX=10116 GN=Dsc1 PE=4 SV=2 CANONICAL=A0A0G2KA90-1" }, "locus": { "chromosome": "18", "start_pos": 11528193, "end_pos": 11502773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000078207.2", "url": "https://www.ensembl.org/id/ENSRNOT00000078207.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075307.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075307.2" } ] } }, { "isoform_ac": "A0A8I6GE75-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90/entry#A0A8I6GE75-1", "sequence": { "sequence": "MAAACAAPGSTFSKQLLFLLLVLVLLCNACQKVSLQVPSHLKAEKPIGKVNLEECLKSPSLILSSDPAFRILEDGTIYATHDLLLSSEKRGFSILLSDSQGQEQKKLEIVLSAREKKAFRKRHTKEPVHKRSKRRWAPIPCSLMENSLGPFPQHVQRIQSDFSQNYSIFYSISGPGVDKEPFNLFYIEKDTGDIYCTRSIDREEYDQFMVYGYATTADGYAPEYPLPLLFKVEDDNDNAPYFETKLTVFSVPENCRYGTSVGQVTAIDKDEPGTLHTRLKYKILQQIPDHPKHFTVHPDTGVITTTTPLLDREKCDTYKLVMEVRDMGGQPFGLFTTGTITISLEDENDNSPCFTQSSYFAEVDENRIDVEILRMMVQDQDLPNTPHSKAVYKILQGNENGNFKITTDPNTNEGVLCVVKPLNYEVSRQVTLQISVLNEAQFTNAANTQPPTMCTATVTVKIKDRDEGPECLPPVKVIQSKDGLPAGQQLLGYKAMDPETSSGEGLRYKMVGDEDNWFEINESTGDLRTVKVLDRESKFVKNNQYNISVVAMDSVGRSCTGTLVVLLEDFNDHPPQIDKDITICQQEKDYAVLEPVDLDGPDNGPPFQFLLDNSSSKLWTLESQDGKRAILRQRHNLNYNYYSVPIQIQDRHGFSAKHVLSVRVCDCTIPSECRMAIEERDVKPNVILGKWAILAMVLGSALLLCILFTCFCVTTTKRTVKKCFPDDVAQQNLIVSNTEGPGEEVTEANIRLPTQTVNICDTSTSVGTLGGQGIKTQQNFEMVKGGYTLESNKGGGHHTLESSKGGVLGAADTGRYAYTDWQTFTQPRLGEESIRGHTLIKN", "length": 842, "header": "tr|A0A8I6GE75-1|A0A8I6GE75_RAT Computationally mapped isoform of Desmocollin 1 OS=Rattus norvegicus OX=10116 GN=Dsc1 PE=4 SV=1 CANONICAL=A0A0G2KA90-1" }, "locus": { "chromosome": "18", "start_pos": 11528193, "end_pos": 11503064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000118489.1", "url": "https://www.ensembl.org/id/ENSRNOT00000118489.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000085728.1", "url": "https://www.ensembl.org/id/ENSRNOP00000085728.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-RNO-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-RNO-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-RNO-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K230-1", "protein_name": "Desmocollin 3", "gene_name": "Dsc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMAMAVPELRSLPYRAPFTKFLLTLWVFSFVGEACKDVTFYVPSTLEADKIIGRVSLKECLSSADGIMPSDPDFRVLDDGSVYPTRAVVLSDEKRSFTIQLSDSKMRKQKEITVILERQKEVMMKRHTNETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVQSDSAQNYNIFYSISGRGVDQEPLNLFFIERDTGNLYCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIKVEDENDNYPLFTEAIYNFEVPESSRLGTVVGTVCATDKDEPDTMHTRLKYSILEQSPPSPGLFSVHPDTGVITTVSHYMDREVVDKYKLILKVQDMNGQFFGLISTSTCIITVQDSNDNAPTFRQNAYETSVEENTYNVEILRIPVDDKDMVNSANWKANFTILKGNENGWFKITTDPATNEGVLCVVKPLDYEENRQVTLEIGVNNEAPFIRDVASRIPTMNRAMVTVQVRDQNEGPECKPREQIVRIKENSAIGSKINGYKAYDPETKNSNGLRYKKLQDPKDWVSIEEVSGSLTISKILDREIMAPRNDLYNITVMAIDQEGRSCTGTLAVNIEDMNDNAPEIIQDDIVICKPRMGYTDISAVDPDEPIHGPPFQFALASSSPEVNRIWTLNQVNDTAARLSYQKTADVQIYSVPVTVTDRAGQSATKILRVNLCDCTHPSQCLLRSRRAGITLGKWAILAILLGIALLFSVLLTLVCGVVTAQKGKHFPEDLAQQNLIISNTEAPGDDRVCSANGFTTHTANNSSQGFCGTMGSGMRNGGQETIEMMKGHQTLDSCRVAGHHHTLDSCRGGHMETDNCRYTYSEWHSFTQPRLGEKLHVCNQNEDHIPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEEGLDFLNNLEPKFLTLAETCTKR", "length": 900 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6QR67-1", "protein_name": "DSC1 protein", "gene_name": "DSC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVASAAPGSIFWKQLLFSLLVLILFCDACQKISLQVPSHLRAEALVGKVNLKECLQSASLILSSDPDFRILEDGSIYTTHDLVLSSGKSFSILLSDSQGQGQKEIEIILEAGGKKVPKRHMKDAVLRRSKRRWAPIPCSLMENSLGPFPQHVQQVQSDAAQNYTIFYSISGPGVDKEPFNLFFIEKDTGDIFCTRSIDREQYQEFPIYAYATTADGYAPEYPLPLVFKVEDDNDNAPYFENKLTVFTVPENCRTGTSVGKVTAIDLDEPDTLHTRLKYKILQQIPNNPRHFTVHPDTGVITTTTPLLDREKCDTYKLIMEVRDMGGQPFGLFNTGTITISLEDENDNAPYFTETSYTVEVEENRIDVEILRMAVHDHDLPNTPHSRAVYQILQGNENGTFKISTDPNTNEAVLCVVKPLNYEVNRQVVLQIGVLNEAQFAKAVNSKTTTTMCTTVVTVKVKDHDEGPECQPPVKVIQSEDCLPAGTELLGYKAVDPERGTGEGLRYKKIQDEDNWFEINEYTGDLKTVKVLDRESTFVKNNQYNVSVIAFDADGRSCTGTLVVFLEDKNDHPPQIKQEELTICRHDKDYVVLEPTDQDGPDNGPPFQFILDNSASKLWTVETRDGKTAILRGRQDLDYDYYTVPIQIKDRHGASATHILPVRVCDCTIPSECRMPSKLSREAALANVFLGKWAILAMVLGSVLLLCILFTCFCVTVKKTVKKCFPEDVAQQNLIVSNTEGPGEEVMDANIRLPTQTSNVCDTSISVGTLGGQGVKTQQSFEMVKGGYTLDANKGGGHQTLESVKGVTDTGRYTYSDWHNFTQPRLGEKVYLCGQDEEHKLCEDYVRSYSYEGKGSVAGSVGCCSDRQEEEGLDFLDHLEPKFRTLAKTCVKK", "length": 893 }, "evidence": [ { "id": "A0A0G2KA90", "url": "https://omabrowser.org/oma/group/A0A0G2KA90/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZJR7-1", "protein_name": "Desmocollin 2", "gene_name": "Dsc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAGSSRSGSPALGLGHLLTLAILALACDACKEVVLQVPSELPAGKFVGRVNLMECLKSANVIHLSDPDFQVFEDGSVYTTNSVVLSSGQRSFTIWLFNTDSQEERELSVHLEGPVEVLNQRLHTEKVLRRAKRRWAPIPCSMMENSLGPFPLFLQQIQSDKAQNYTIYYSISGPGVDKEPVGLFRIDRDTGNLYCTDRVDREQYDSFELTALAMTPDGYMVENLLTLLIKVEDENDNYPIFTQKVYSFTVLENSPFGSHVGEVCATDKDEPDTMHTRLKYSILEQSPSPPMLFTMHPRTGVITTTSTQLDRELIDKYQLIIKVQDMDGQYFGLQTTATCVITIGDVNDNLPTFTRTTYVTSVEENTVNVELLRLSVQDKDLVNSPNWRANYTILKGNENGNFKIKTDPQTNEGILCVIMPLDYEERQRVTLEIGVVNEAPYTRQAGSKSSMSTATVTVNVKNQDEGPECIPQTQTVRIRENVPIGTRNDGYKAYDPETKNSIGIRYRKLSDPKGWITVNEDSGSITIFRTLDREAETIRNGIYNITVLALDADGRSCTGTLGILLEDVNDNGPFIPKQTVVICRATMSSAEIVAVDPDEPANGPPFDFSLESSDSEVRRRWKLTRINDTAASLSYQNDPAFDSYVIPVRVTDRFGLSSVTSLNVVVCDCITESDCTYRTGERTGYADVRLGPWAILAILLGVALLLCILFTLVCSVSRASKQQKILPDDLAQQNLIVSNTEAPGDDKVYSANGFTAQTAGASGQTTFTTLGAGVKSTGQETIEMVKGGQRTLDSRRATGYHHHTMDPGRGGHVEVDNYRYTYSEWHNFTQPRLGEKVQFCHEDDNQKLAQDYVLTYNYEGKGSAAGSVGCCSDLQEEDGLEFLDHLEPKFRTLAEVCAKR", "length": 902 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QSQ0-1", "protein_name": "Desmocollin 2-like protein", "gene_name": "dsc2l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRTPPRPEGLYPSPTVRYTQFMVETGHIQLLQITYPHTHSRFRMYERAHFAACLLALVLFQRAESCDPRPVLVQVPNTVPAGYFITQVTLNGCTAIPVSFTSSDPDFTVNTDGSIVTLRSLVISTKRFSVLVQDNSGLDWRVEIILSCKNEDSQKSGSVAQKRAKRRWRPLPFSVVENASPPFPKDVEMIASDSSVNYTVHYVISGQGVTEEPIGLFQLDQKTGMVRVTGPVDREKNPEFNFIARAFDQNNREVDQFLPITVMVEDVNDNAPEFTGNRFFTVEERCRAGTRVGQVNATDRDQPKTPHSLIKYILLNATDMFSIDQSTGIITAKSNTLDREAQDKVFVGVEIRDMGGAPNGLFNRGTAVISLTDVNDNPPTFKEKLYKGTIKENLANVLVTRIPVEDKDLVNTPNWKAVYEVTKGNENGNFRMETDPKTNEGLLYVVKGLDFEKTPVMNLEVTARNEAPLVGTDAKWQSVPLQLNVEDVDEGPEFNPNIMYLKVKENLPNGTVIGTYKALDPETKNSNGIKYYKLTDPGNWITVVESTGELKVANTIDRESSLVHNDTYNITIKAVDESKKTGNGVVILQIEDVNDNIPVIQRPDLNMCNRGDAVSSVLVEAVDQDKPPYSTPFIFELGAEQEGKWKLKDITDSSVVLQQVEPMPNGMYTVPITVKDLQGTGKEQIVNVRVCSCQREDSGVGICGARSASVSLGNYGILALVLSGLLLLLLCLFLIFFCTTKRDKLQITDDTGTGGILLKSNTEAPGEEVKDGTLLLIPTADVVDGSFQSAVTESKNVNTAPGRYGQQFFQSGGVYNTTTQEFGTDQYYTSGRYDNKIYGNGTLQKFSNTGTLDTWRTNGCYLDRKLAYFGEQEDGRYADDLLKNYGNEGVGSSAGSVGCCSILGEQESMEFLNTLGPKFRPLADICYTTNKTGK", "length": 934 }, "evidence": [ { "id": "RGD:1310768", "url": "https://alliancegenome.org/gene/RGD:1310768#orthology", "database": "AGR" }, { "id": "MGI:109173", "url": "https://alliancegenome.org/gene/MGI:109173#orthology", "database": "AGR" }, { "id": "HGNC:3035", "url": "https://alliancegenome.org/gene/HGNC:3035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SAM0-1", "protein_name": "Desmocollin 1", "gene_name": "DSC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVASAAPGSDFCKQLLFSLLVLILFCDACQKISLQVPSHLPAEALVGKVNLKECLQSASLIQSSDPDFRIQEDGSIYTTHDLMLSSEKKSFSILLSDTQREEQKKIAIVLEAGGQKGPERHLEDTVLKRSKRRWAPIPCSLMENSLGPFPQHVQQVQSDAAQNYTIFYSISGPGVDKEPFNLFFINKDTGDIFCTRSIDREQYEQFPLYAYATTADGYAPEYPLPLLFKVEDDNDNAPYFENKVTIFSVPENCRTGTSVGKVTAIDHDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTTPLLDREKCDTYKLIMEVRDMGGQPFGLFNTGTITISLEDENDNSPYFTETSYFTEVEENRIDVEILRMAVRDQDLPNTPHSKAIYKILQGNENGNFKISTDPNTNEGVLCVVKPLNYELNRQIVLQIGVLNEAQFSKAANAQTPTMCTTTVTVKIKDLDEGPECQPSVKVIQSKDGLPAGKELLGYKAVDPEKGSSEGLRYKKIGDEDNWFEINEHTGNLKTVKVLDRESKFVKNNQYNVSVIAMDADGRSCTGTLVVFLEDDNDHPPDIREKEVTICRHDKDFAVLEPVDLDGPDNGPPFQFFLDNAASKLWTIETKDGKTAILRERQNLDYDTYTVPIQVKDRHGFAARHILAVRVCDCTTPSDCKMTPKGVRDIKPSNVILGRWAILAMVLGSALLLCILFTCFCVTAKKTVKKCFPEDVAQQNLIVSNTEGPGEEVMEANMRLPTQTCNICDTSVSVGTLGGQGVKTQQSFEMVKGGYTLDSSKGGGHQTLESVKGLGQGGMDTGRYGYTEWHSFTQPRLGEVYLCGQDEEHKHSEDYVRSYNYEGKGSVAGSVGCCSDRQEEEGLEFLDHLEPKFRMLAKTCVKK", "length": 896 }, "evidence": [ { "id": "A0A0G2KA90", "url": "https://omabrowser.org/oma/group/A0A0G2KA90/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P55292-1", "protein_name": "Desmocollin-2", "gene_name": "Dsc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVGSMRSGSPAFGLGHLLTLAILALASDACKEVVLQVPSELPAEKFVGRVNLMDCLKSADIVHLSDPDFQVLEDGSVYTTSSVVLSSGQRSFTIWLFSTDSQEEREISVHLEGPVEVLNKRPHTEKVLSRAKRRWAPIPCSMLENSLGPFPLFLQQIQSDTAQNYTIYYSIRGPGVDKEPLNLFYVERDTGNLYCTGRVDREQYESFELTAFATTPDGYTPEYPLPLLIKIEDENDNYPIFTQKLYSFTVQENSRIGSIVGEVCATDLDEPDTMHTRLRYSILEQSPSPPMLFTMHPSTGVITTTSAQLDRELIDKYQLLIKVQDMDGQYFGLHTTAKCIITIEDVNDNLPTFTRTTYVTSVEENTVNVEILRLTVQDKDLVNSPNWRANYTILKGNENGNFKIVTDPKTNEGILCVIKPLDYEERQQVTLQIGVVNEAPYTREASSKSPMSTATVTVTVTNQDEGPECIPPMQTVRIQENVPVGTRNDGYKAYDPETRSSSGIRYRKLSDPRGWVTVNEDSGSITIFRALDREAETVRNGIYNITVLALDADGRSCTGTLGIILEDVNDNGPFIPKQTVVICKATMSSAEIVAVDLDDPVNGPPFDFSLESSDSEVQRMWRLTRINDTAARLSYQNDPSFGSYAVPIRVTDRLGLSSVTTLNVLVCDCITESDCTLRSGERTGYADVRLGPWAILAILLGIALLFCILFTLVCSVSRASKQQKILPDDLAQQNLIVSNTEAPGDDKVYSTNGLTTQTMGASGQTAFTTMGTGVKSGGQETIEMVKGGQQTLDSRRGAGYHHHTLDPCRGGHVEVDNYRHTYSEWYNFIQPRLGDKVQFCHTDDNQKLAQDYVLTYNYEGKGSAAGSVGCCSDLQEEDGLEFLDHLEPKFRTLAEVCAKR", "length": 902 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55849-1", "protein_name": "Desmocollin-1", "gene_name": "Dsc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVACAAPGSTFSKQLLFFLLVLVLFCDACQKVSLHVPSHLKAETPVGKVNLEECLKSPSLILSSDPAFRILEDGTIYTTHDLLLSSEKRGFSILLSDGQGQEQKKLEVVLSAREKKVFRKRHTKEPVHNRSKRRWAPIPCSLMENSLGPFPQHIQQIQSDAAQNYTIFYSISGPGVDKEPYNLFYIEKDTGDIYCTRSIDREQYDQFLVYGYATTADGYAPDYPLPLLFKVEDDNDNAPYFETKLTVFSVPENCRSGTSVGQVTAIDKDEPGTLHTRLKYKILQQIPDQPKHFSIHPDTGVITTTTPLLDREKCDTYKLVMEVRDMGGQPFGLFTTGTITISLEDENDNSPYFTQTSYTTEVEENRIDVEILRMVVHDQDLPNTPHSKAVYTILKGNENGNFKITTDPNTNEGVLCVVKPLNYEVSRQVTLQIGVLNEAQFTNAANAQPPTMCTTTVTVKIKDRDEGPECQPPVKVIQSKDGLPAGQELLGYKAVDPETSSGEGLRYEMVGDEDNWFEINKITGDLRTVKVLDRESKFVKNNQYNISVVATDTAGRSCTGTLVVLLEDFNDHPPQIDKEVTICQQEKDFAVLEPIDLDGPDNGPPFQFLLDNSSSKLWTLESQDGKRAILRQRHNLNYNYYSVPIQIQDRHGFSAKHVLSVRVCDCTTPTECRMAVKEERDAKPNIILGKWAILAMVLGSALLLCILFTCFCVTTTKRTVKKCFPDDVAQQNLIVSNTEGPGEEVTEANIRLPTQTANICDTSMSVGTLGGQGIKTQQSFEMVKGGHTLESHKGGVLGAAEPGRYAYTDWQTFTQPRLGEKVYLCGQAEEHKHCEDYVRPYNYEGKGSMAGSVGCCSDRQEEEGLEFLDQLEPKFRTLAKTCVKK", "length": 886 }, "evidence": [ { "id": "RGD:1310768", "url": "https://alliancegenome.org/gene/RGD:1310768#orthology", "database": "AGR" }, { "id": "MGI:109173", "url": "https://alliancegenome.org/gene/MGI:109173#orthology", "database": "AGR" }, { "id": "HGNC:3035", "url": "https://alliancegenome.org/gene/HGNC:3035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" }, { "id": "A0A0G2KA90", "url": "https://omabrowser.org/oma/group/A0A0G2KA90/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55850-1", "protein_name": "Desmocollin-3", "gene_name": "Dsc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVPEFRSPQCRALCTKLLLTLWVFSFVGEACKKVTFHVPSTLEADKIIGRVSLKECLSSADGIMPSDPDFRVLDDGSVYPTRAVVLSDEKRSFTIQLSDSKMQTQKEIPVILEHKKKVLKKRHTKETVLRRSKRRWAPIPCSMQENSLGPFPLFLQQVQSDAAQNYTVFYSISGRGADQEPLNWFFIERDTGNLYCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIKIEDENDNYPLFTEAIYAFEVPEGSRLGTVVGTVCATDKDEPDTMHTRLKYSILEQTPPSPGLFSVHPDTGVITTVSHYMDREVVDKYKLIMKVQDMNGQFFGLISTSTCIITVQDSNDNAPTFRQNTYETAVEENTYNVEILRIPVDDKDMINTANWKANFTILKGNENGWFKITTDPVTNEGVLCVVKPLDYEENRQVTLEIGVNNEAPFIKDVANRIPTMNRAMVTVHVKDQNEGPECKPPEQYVRIKENSAVGSKINGYKAYDPETKNSNGLRYKKLQDPKDWVSIEEVSGLLTISKTLDREIMAPRNDMYNITVMAIDQEGKSCTGTLAVNIEDVNDNAPEIIQDYIVICKPKMGYTDISAVDPDEPIHGPPFQFNLANTSPEVNRIWTLNQVNDTAARLSYQKTADVQIYNVPVTVKDRAGQSATKILRVNLCDCTHPSQCPLRSRSAGITLGKWAILAILLGIALLFSVLLTLVCGVVTARKGKHFPEDLAQQNLIISNTEAPGDDRVCSANGFTTHTANNSSQGFCGTMGSGMRNGGQETIEMMKGHQTLDSCRVAGHHHTLDSGRGGHMDTDNCRYTYSEWHSFTQPRLGEKLHVCNQNEDHIPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEEGLDFLNNLEPKFLTLAETCTKR", "length": 896 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q02487-1", "protein_name": "Desmocollin-2", "gene_name": "DSC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTAANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKVYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGCCSERQEEDGLEFLDNLEPKFRTLAEACMKR", "length": 901 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08554-1", "protein_name": "Desmocollin-1", "gene_name": "DSC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGEKVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCIKK", "length": 894 }, "evidence": [ { "id": "RGD:1310768", "url": "https://alliancegenome.org/gene/RGD:1310768#orthology", "database": "AGR" }, { "id": "MGI:109173", "url": "https://alliancegenome.org/gene/MGI:109173#orthology", "database": "AGR" }, { "id": "HGNC:3035", "url": "https://alliancegenome.org/gene/HGNC:3035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" }, { "id": "A0A0G2KA90", "url": "https://omabrowser.org/oma/group/A0A0G2KA90/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14574-1", "protein_name": "Desmocollin-3", "gene_name": "DSC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEACTKR", "length": 896 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-031116-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-55#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "establishment of skin barrier", "id": "GO:0061436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061436", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA90", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA90" } ], "pmid": "" }, { "name": "hair follicle morphogenesis", "id": "GO:0031069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031069", "evidence": 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