{ "uniprot_canonical_ac": "A0A0G2K809-1", "uniprot_ac": "A0A0G2K809", "uniprot_id": "A0A0G2K809_RAT", "mass": { "chemical_mass": 112907.0, "monoisotopic_mass": 112907.0 }, "refseq": { "ac": "XP_038943653", "name": "protein AF-17 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943653" }, "gene_names": [ { "name": "Mllt6", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809", "id": "A0A0G2K809" }, { "name": "Mllt6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943653", "id": "XP_038943653" } ], "protein_names": [ { "name": "MLLT6, PHD finger containing", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809/entry#names_and_taxonomy", "id": "A0A0G2K809" }, { "name": "protein AF-17 isoform X3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943653", "id": "XP_038943653" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Mllt6", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809", "locus": { "chromosome": "10", "start_pos": 82676073, "end_pos": 82656872, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000053285", "url": "https://www.ensembl.org/id/ENSRNOG00000053285" } ] } } ], "crossref": [ { "id": "RGD:1306689", "url": "https://alliancegenome.org/gene/RGD:1306689", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2K809", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2K809", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000053285", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000053285", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15574", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15574", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15709", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15709", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "303504", "url": "https://www.ncbi.nlm.nih.gov/gene/303504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EKHPAHH", "url": "https://omabrowser.org/oma/group/EKHPAHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2K809", "url": "https://www.orthodb.org/?gene=A0A0G2K809", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_038943653", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943653", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1306689", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306689", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K809-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTSRHSSGGGGGAGGGGSGGSGSGTSGGGGGTGGGGSSNSFLSGRRSRSASPSTQQEKHPTHHEKGQKKSRKDKERLKQKHKKRPESPPSILAPPVVPTADKVSATTSSHHEASTQETSESSRDSKGRKSSSHSLSHKGKKLGSGKGVSSFTSASSSSSSSSSSSSSGGPFQPAGSSLQSSPDFAAFPKLEQPEDDKYSKPPAPTPPAPPSPTIPEPPKADLFEQKVVFSGFGPIMRFTTTTSSSSRARAPSPGDYKSPHVSGSGTSAGSHKRMPALSATLGPAEEAPETTLKEKKHKASKRSRHGPGRPKGSRGKEGATGPTASLPAAQLAGFTATAASPFSGGSLVSSGLGGLAPRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHGGGMLRAVCSTPLSSSLLGPTGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPASHIFGTPMGTVNPLLTQAESSHTEPDLEDCSFRCHGTSPQESLSSMSPISSLPALFDQTSAPCGGGQLDSTAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLLPQAGSSDSLSISKSPPGKNCLGLDNTLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGSLPLNGLLGGLNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGSKGGTADKGASASQEKG", "length": 1104, "header": "tr|A0A0G2K809-1|A0A0G2K809_RAT Isoform 1 of MLLT6, PHD finger containing OS=Rattus norvegicus OX=10116 GN=Mllt6 PE=1 SV=2 CANONICAL=A0A0G2K809-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K809-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809/entry#A0A0G2K809-1", "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTSRHSSGGGGGAGGGGSGGSGSGTSGGGGGTGGGGSSNSFLSGRRSRSASPSTQQEKHPTHHEKGQKKSRKDKERLKQKHKKRPESPPSILAPPVVPTADKVSATTSSHHEASTQETSESSRDSKGRKSSSHSLSHKGKKLGSGKGVSSFTSASSSSSSSSSSSSSGGPFQPAGSSLQSSPDFAAFPKLEQPEDDKYSKPPAPTPPAPPSPTIPEPPKADLFEQKVVFSGFGPIMRFTTTTSSSSRARAPSPGDYKSPHVSGSGTSAGSHKRMPALSATLGPAEEAPETTLKEKKHKASKRSRHGPGRPKGSRGKEGATGPTASLPAAQLAGFTATAASPFSGGSLVSSGLGGLAPRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHGGGMLRAVCSTPLSSSLLGPTGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPASHIFGTPMGTVNPLLTQAESSHTEPDLEDCSFRCHGTSPQESLSSMSPISSLPALFDQTSAPCGGGQLDSTAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLLPQAGSSDSLSISKSPPGKNCLGLDNTLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGSLPLNGLLGGLNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGSKGGTADKGASASQEKG", "length": 1104, "header": "tr|A0A0G2K809-1|A0A0G2K809_RAT Isoform 1 of MLLT6, PHD finger containing OS=Rattus norvegicus OX=10116 GN=Mllt6 PE=1 SV=2 CANONICAL=A0A0G2K809-1" }, "locus": { "chromosome": "10", "start_pos": 82675124, "end_pos": 82657678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000092122.2", "url": "https://www.ensembl.org/id/ENSRNOT00000092122.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000074424.2", "url": "https://www.ensembl.org/id/ENSRNOP00000074424.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 389, "start_aa": "Thr", "end_pos": 389, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr389", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 397, "start_aa": "Thr", "end_pos": 397, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr397", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 507, "start_aa": "Thr", "end_pos": 507, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr507", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KGP1-1", "protein_name": "Alhambra, isoform P", "gene_name": "Alh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCERNNNKQVTSSNKIPSSFNAKLELDSSKDDTIHSTSLNKKLVKIKKFKLDDMKEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITSSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSSSSSSSSSSTGGAPNPSSSSVHSGSASNMTGGGSVLPGSSNIGNISNSLNNNLPGGSSSTSSAGNVPGGSGGIISASSGGATQSTSSQSSTAPGTTKSSASSSSSSSNSYKEKHSKSLSKSTSSKDKDGKDSSTNSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINTQPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSVSNLSNSSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGSSASNMPGTIAPGTGGVSSSAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSSSKKRKADSAKSTSSISTSGSALEDNNSLISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSESHSASSRSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGTTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRSRSGESGSSHHHAHAHHHHHHPTHHNSHHQQNPQQQQQLHQQQQQNASSHMHACTNSSSSTSTSTTSSSLSGGTAPATSSSNSKGPSRSGKKRGAAMNKSESTSVATTATPATVAATPAEKQSRHSSPHYSATPTPPPTSTLPPVVSSPVVMLQSLSSSSIDSPPATAAAGATSNSRNTRNNSSNGNHNGEQTSSSSSSSSSSSSGGGGTSGAANVVNLLDSPVNMSASGNYRSSSNSTGNALPAASSNASQAKPLNKKMLRAQQTQLYQQQQQQQQYAPPARSISPTNLSSASASNSASLTHLQQQQQSHQQHEDLEILQFTNTNTTASSNTPTSKPNNRTLDLSTASASSSSPSAVPATTSPLVVLSNQLPLNSVAASSSTGGLKFTYESQTQMDVPMMPVSAIKDSPPSSPGSEIGSAMHSATTAPGSLTGASTAATAQPGNVRKRGRKAKDATIAAAAAAAAAAAALSNSQQDLKDVRILQNGASNTPGNPAGSTPTPPATPASSNAVSSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTPDSMNSQYAGVPFPGKQRNSTAVPSNATPAQNPLQSMFSGGGMNGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASNTKAEAHGK", "length": 1717 }, "evidence": [ { "id": "RGD:1306689", "url": "https://alliancegenome.org/gene/RGD:1306689#orthology", "database": "AGR" }, { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" }, { "id": "HGNC:7138", "url": "https://alliancegenome.org/gene/HGNC:7138#orthology", "database": "AGR" }, { "id": "MGI:1935145", "url": "https://alliancegenome.org/gene/MGI:1935145#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I5ZKY6-1", "protein_name": "MLLT10, histone lysine methyltransferase DOT1L cofactor", "gene_name": "Mllt10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKPKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTAARFTNANFQEVSAHTSSGKDVSEARSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSASSPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYTHTQPPPSTKDVHKGEPGSQDAGVNSFSSLVGHPGTSGATSQPKSFDSSPGELGSSSLPTAGYKRAQTSGVEEEEAVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSVTSCSLQKSPTLLRNGSMQSLSVGSSPLGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHIPQQSSGHLQQVGALSPSAASSVTPAAATTQANTAPGSSLSQAPAHVYGSRLNQNPSMAVLIAQSESSQTDQDLGDNTRSLVGRGSSPRGSLSPRSPVSNLQIRYDQPSSSGLESLPPVAVSIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPAITTNPSPSHQIHTYTAQTAPTTDSLNSSKSPHIGNSFVPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGPLASGMQTVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVIQTPVTISQNPAPLTHTSVPPNAAHPMPAAALTNSASGLGLLSDQQRQMFLQQQQFQQLLNSQQLTPEQHQAFLYQLMQQQHHPPELQQMQLPGPTQIPINNLLAGPPAPPLHTATTNPFLTIHGDSTSQKVTRLSDKTGPVAQEKS", "length": 1068 }, "evidence": [ { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6YVP0-1", "protein_name": "Protein AF-10 isoform X1", "gene_name": "mllt10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCAYFSQRIVSSKFDEEDSYFRECEMVSSELYLAEEDDDSPSNMKEMIGGCCVCSDERGWAENPLVYCDGHGCNVAVHQACYGIVQVPTGPWFCRKCESQERAARVIKGWRGRKPSWQTPEGGGQSTTCNKEEEDSRLSRSLKTLNIVRCELCPQKDGALKRTDNGGWAHVVCALYIPEVEFANVSTMEPIVLQSVPHERYNKTCYICEEQGRESKAATGACMTCNKHGCRQAFHVTCAQLAGLLCEEQGSDADNVKYCGYCKYHYNKLRRSKGRGSRAQSLSDSSTHSLDKHHDKEKKKHKERDRHKPKHKKPLELSPSLVPALMVTPEKSYNNSSSGGSVSSISSTQKRLDDSGARFTNANFQEVPPHSSSSSKDGGSSDGKSSDSKSKKSSHSTSSSSGSRGRKSVAGKPHGPVVTTATSSTAPSSTSPFQQGHLLGSNSSSKSATSGSVVQPTSDFLSFSDPSLRAGDSYTPPSFGRCHMKGGAESGASESMVALNTFSMIPLSQSSSSSSSKHYENCHTTGELGSLASASYKRPQPSSSSSSATSSSSTGEDGVKKKKRGNWRNRYGPCFTTQDSKTTDAGEHISTMPSSTSPSPSSMSNMVCRGSTVSSTASVGAVGAGTSSLGIQKSPSLLRNGSLQGMTVSSPPAVPGEQKRSYPSSSDVACPLPSAVLGGSMSASNSELPAHQSVVVTSMPTLTSLPSAAPFTSTPSTHANSLPGSFNLAPSHMFGNRLNPNSAMAALIAQSEGSPADQELGDGALGFSRRGNSPKTNLSPRSPLSGLHIRYDAGPMVPGLGSGSDTLPPAATSIDQLLERQWNEGQQFLLQQGSQGDVLAMLKSLHQLQVENRRLEEQIRTLTMKKERLQLLSAQLSVPFTPASTTATTASSPMYPSNTHTDMLHSKSIQLGSVLTESSQPLPTQDPQSGGHSSGSSTSSLSTPPSAAHSPPQQQVNGVGMAGVPVQPGNANSSLPAIAGVTGLMGALQGNHLAMSGIVGALNGVIQTSQSSLTQNSSPLPQSATASSASLSMSSSLTNSSMSTTKTRLFTEQHRQILLHQHQLQQLFGSQQPTPEQQQVLLYQLMQQQQQQQQQQQQNDIQFQQLPINSLLPGNQPTTSTNPFLAHHNDNNTPKAGVNTAAIKQTKRLGEKAVPVTGQEKT", "length": 1162 }, "evidence": [ { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AR10-1", "protein_name": "Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6", "gene_name": "Mllt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTSRHSSGGGGGAGGGSSGGGGGGSSSASGGGGGTGGGSGNSFLSGRRSRSASPSTQPEKHPTHHEKGQKKSRKDKERLKQKHKKRPESPPSVLAPPAVPTADKVSSATSSSHHEASTQETSESSRDSKGRKSSSHSLSHKDKKLGTGKGVSSFTSASSSSSSSSSSSSSSSGGPFQPAGSSLQSSPDFAAFPKLEQPEEDKYPKPADPTPPAPPSPTAPEPPKADLFEQKVVFSGFGPIMRFTTTASSSSRARAPSPGDYKSPHITGAGASAGTHKRMPALSATLGPAEEAPETTLKEKKHKASKRSRHGPGRPKGSRGKEGASGPTASLPAAQLAGFTATAASPFSGGSLVSAGLGGLASRTFGPSGSLPSLSLESSLLGAGIYTSNKDPISHGGGMLRAVCSTPLSSSLLGPTGTSALPRLSRSPFTSTLASSSASISTTQVFSLAGSTFSLPSSHIFGTPMGTVNPLLTQAESSHTEPDLEDCSFRCHGTSPQESLSSMSPISSLPALFDQTSAPCAGGQLDSTAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQVLNVQLSVPFPALPAALPATNGPIPGPYGLLPQAGSSDSLSVSKSPPGKNSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGATGLGAMPMAEGLLGGLAGSGSLPLNGLLGGLNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQMQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGPKGGTADKGASTSQEKG", "length": 1109 }, "evidence": [ { "id": "RGD:1306689", "url": "https://alliancegenome.org/gene/RGD:1306689#orthology", "database": "AGR" }, { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" }, { "id": "HGNC:7138", "url": "https://alliancegenome.org/gene/HGNC:7138#orthology", "database": "AGR" }, { "id": "MGI:1935145", "url": "https://alliancegenome.org/gene/MGI:1935145#orthology", "database": "AGR" }, { "id": "A0A0G2K809", "url": "https://omabrowser.org/oma/group/A0A0G2K809/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O54826-1", "protein_name": "Protein AF-10", "gene_name": "Mllt10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYEQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTAARFTNANFQEVSAHTSSGKDVSEARGSEGKGKKSSAHSSGQRGRKPGAGRNPGTAVSASSPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRSDSYTHTQQPSSTKDVHKGESGSQEAAVNSFSSLVGHPVTSTVISQPKSFDNSPGELGSSSLPTAGYKRAQTSGIEEEAVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSVTSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHIPQQSSGHLQQVGALSPSAASSVTPAAATTQANTVSGSSLSQAPAHMYGSRLNQNPSMAVLIAQSESSQTDQDLGDNARSLGGRGSSPRGSLSPRSPVSNLQLRYDQPSNSSLETVPPVAASIEQLLERQWSEGQQFLLEQGTPGDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPAITTNPSPSHQMHTYTAQTAPPPDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQSSGVSGVQQVNGVTVGALASGMQTVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVIQTPVTISQNPAPLTHTSVPPNAAHPMPAAALTNSASGLGLLSDQQRQMFIQQQQFQQLLNSQQLTPEQHQAFLYQLMQQQHHPPELQQLQLPGPTQIPINNLLAGAQAPPLHTATTNPFLTIHGDSTSQKVTRLSDKTGPVAQEKS", "length": 1068 }, "evidence": [ { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55197-4", "protein_name": "Protein AF-10", "gene_name": "MLLT10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPEQHQAFLYQLMQHHHQQHHQPELQQLQIPGPTQIPINNLLAGTQAPPLHTATTNPFLTIHGDNASQKVARLSDKTGPVAQEKS", "length": 1068 }, "evidence": [ { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P55198-1", "protein_name": "Protein AF-17", "gene_name": "MLLT6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGNNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGGTADKGASANQEKG", "length": 1093 }, "evidence": [ { "id": "RGD:1306689", "url": "https://alliancegenome.org/gene/RGD:1306689#orthology", "database": "AGR" }, { "id": "FB:FBgn0261238", "url": "https://alliancegenome.org/gene/FB:FBgn0261238#orthology", "database": "AGR" }, { "id": "HGNC:7138", "url": "https://alliancegenome.org/gene/HGNC:7138#orthology", "database": "AGR" }, { "id": "MGI:1935145", "url": "https://alliancegenome.org/gene/MGI:1935145#orthology", "database": "AGR" }, { "id": "A0A0G2K809", "url": "https://omabrowser.org/oma/group/A0A0G2K809/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "negative regulation of urine volume", "id": "GO:0035811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035811", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "positive regulation of sodium ion transport", "id": "GO:0010765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010765", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "renal system process", "id": "GO:0003014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003014", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "renal water absorption", "id": "GO:0070295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070295", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "renal sodium excretion", "id": "GO:0035812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035812", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "renal potassium excretion", "id": "GO:0036359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036359", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K809", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K809" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1086, "end_pos": 1088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0G2K809-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1104, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2K809-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A0G2K809" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 389, 397, 507 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1046, "end_pos": 1048 }, { "start_pos": 1086, "end_pos": 1088 }, { "start_pos": 117, "end_pos": 119 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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