{ "uniprot_canonical_ac": "A0A0G2K7Z2-1", "uniprot_ac": "A0A0G2K7Z2", "uniprot_id": "A0A0G2K7Z2_RAT", "mass": { "chemical_mass": 41201.0, "monoisotopic_mass": 41201.0 }, "refseq": { "ac": "NP_001382565", "name": "WD repeat-containing protein 86", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382565" }, "gene_names": [ { "name": "Wdr86", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2", "id": "A0A0G2K7Z2" }, { "name": "RGD1566180", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382565", "id": "NP_001382565" }, { "name": "Wdr86", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382565", "id": "NP_001382565" } ], "protein_names": [ { "name": "WD repeat domain 86", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2/entry#names_and_taxonomy", "id": "A0A0G2K7Z2" }, { "name": "WD repeat-containing protein 86", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382565", "id": "NP_001382565" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Wdr86", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2", "locus": { "chromosome": "4", "start_pos": 10441465, "end_pos": 10424008, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000025735", "url": "https://www.ensembl.org/id/ENSRNOG00000025735" } ] } } ], "crossref": [ { "id": "RGD:1566180", "url": "https://alliancegenome.org/gene/RGD:1566180", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2K7Z2", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2K7Z2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000025735", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000025735", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "311956", "url": "https://www.ncbi.nlm.nih.gov/gene/311956", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HGGINWL", "url": "https://omabrowser.org/oma/group/HGGINWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2K7Z2", "url": "https://www.orthodb.org/?gene=A0A0G2K7Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44489:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44489:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001382565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1566180", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1566180", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K7Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSGSALRVCAGHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCQLEDETAFTCSADCTIRSWDVRTGQCLQVYRGHTSIVNRILVANDQLFSSSYDRTARVWTVDKGQMSQEFRGHRNCVLTLAYSAPKDLPRDPCLEAAMGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLDVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYSGSADRTVKCWLADTGERVCTFSAHRHSVSALKYHAGTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVHGQVLYTASHDGALRFWDVRGLQSVPPLPRRPSAKRSLSRLFSNKVACAAPGPLQPA", "length": 380, "header": "tr|A0A0G2K7Z2-1|A0A0G2K7Z2_RAT Isoform 1 of WD repeat domain 86 OS=Rattus norvegicus OX=10116 GN=Wdr86 PE=4 SV=1 CANONICAL=A0A0G2K7Z2-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K7Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K7Z2/entry#A0A0G2K7Z2-1", "sequence": { "sequence": "MGSSGSALRVCAGHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCQLEDETAFTCSADCTIRSWDVRTGQCLQVYRGHTSIVNRILVANDQLFSSSYDRTARVWTVDKGQMSQEFRGHRNCVLTLAYSAPKDLPRDPCLEAAMGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLDVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYSGSADRTVKCWLADTGERVCTFSAHRHSVSALKYHAGTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVHGQVLYTASHDGALRFWDVRGLQSVPPLPRRPSAKRSLSRLFSNKVACAAPGPLQPA", "length": 380, "header": "tr|A0A0G2K7Z2-1|A0A0G2K7Z2_RAT Isoform 1 of WD repeat domain 86 OS=Rattus norvegicus OX=10116 GN=Wdr86 PE=4 SV=1 CANONICAL=A0A0G2K7Z2-1" }, "locus": { "chromosome": "4", "start_pos": 10440595, "end_pos": 10424363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000079770.2", "url": "https://www.ensembl.org/id/ENSRNOT00000079770.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000074405.1", "url": "https://www.ensembl.org/id/ENSRNOP00000074405.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUP4-1", "protein_name": "WD repeat domain 86", "gene_name": "WDR86", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNGGSAVKVCADHQGGINWLSLSPDGQRLLTGSEDGTARLWSTADSQCHGHFQGHESYITFCHLENEAAFTCSADHTIRKWDVVTGQCLAIYRGHTSIVNRILVAKDYLFSGSYDRTARCWSVDKEKQIQEFRGHRNCVLTLAHYSSKDVLEEEEEEEEEEERVSRDLLVTGSTDCTVKVWWVSSGRCYQTLLGHTGAVLCLILDAPNRELFSGSTDYTIRTWNIVTGEQLKVFKEHQGSIICLELVNRHLYSGSADRTVKCWLVDTGERIQTYKAHKHSVSTLKYHAGILFTGSGDACARAFNSRSGVLQKIFRGHKFIINCIQIHNELLYTASHDGTLRIWDIRGICKRNKRRWKKERCAQGRSSQKGSLSRLFNNKVGCMVQQENGEHETVELM", "length": 398 }, "evidence": [ { "id": "A0A0G2K7Z2", "url": "https://omabrowser.org/oma/group/A0A0G2K7Z2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z757-1", "protein_name": "WD repeat domain 86", "gene_name": "Wdr86", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCHLEDEAAFTCSADCTIRRWDVRTGQCLQVYRGHTSIVNRILVANDQLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSAPEDLPQDPCMEAAMGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHAGTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVHGQVLYTASHDGALRLWDVRGLQSVPPLPRRPAAKRSLSRLFSNKVACAAPVPLQPA", "length": 380 }, "evidence": [ { "id": "RGD:1566180", "url": "https://alliancegenome.org/gene/RGD:1566180#orthology", "database": "AGR" }, { "id": "MGI:1915466", "url": "https://alliancegenome.org/gene/MGI:1915466#orthology", "database": "AGR" }, { "id": "HGNC:28020", "url": "https://alliancegenome.org/gene/HGNC:28020#orthology", "database": "AGR" }, { "id": "A0A0G2K7Z2", "url": "https://omabrowser.org/oma/group/A0A0G2K7Z2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3HB57-1", "protein_name": "WD repeat-containing protein 86", "gene_name": "", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTXXXXXXXGRCCALLQGHESYVTFCQLEDEAAFTCSADCTIRRWDVRTGQCRQVYRGHTSIVNRILVANNQLFSSSYDRTARAWTVDKGQVSKEFRGHRNCVLTLAYSAPKDLPSDPCLEAAMGGGLLVTGSTDDTAKVWQVASGCCHQTLRGHTGAVLCLVLDVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYTGSADRTVKCWLADTGERVRTFPAHRHSVSALKYHAGTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVHGQVLYTASHDGALRLWDVRGLQSAPPSPRRPAAKRSLSRLFSNKVACAAPVSLQPA", "length": 379 }, "evidence": [ { "id": "A0A0G2K7Z2", "url": "https://omabrowser.org/oma/group/A0A0G2K7Z2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q86TI4-3", "protein_name": "WD repeat-containing protein 86", "gene_name": "WDR86", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQLEDEAAFTCSADCTIRRWDVLTGQCLQVYRGHTSIVNRILVANNQLFSSSYDRTARVWSVDKGQMSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRNVSALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQVHGQVLYTASHDGALRLWDVRGLRGAPRPPPPMRSLSRLFSNKVGCAAAPLQPA", "length": 376 }, "evidence": [ { "id": "RGD:1566180", "url": "https://alliancegenome.org/gene/RGD:1566180#orthology", "database": "AGR" }, { "id": "MGI:1915466", "url": "https://alliancegenome.org/gene/MGI:1915466#orthology", "database": "AGR" }, { "id": "HGNC:28020", "url": "https://alliancegenome.org/gene/HGNC:28020#orthology", "database": "AGR" }, { "id": "A0A0G2K7Z2", "url": "https://omabrowser.org/oma/group/A0A0G2K7Z2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0G2K7Z2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 380, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2K7Z2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A0G2K7Z2" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }