{ "uniprot_canonical_ac": "A0A096MKA9-1", "uniprot_ac": "A0A096MKA9", "uniprot_id": "A0A096MKA9_RAT", "mass": { "chemical_mass": 92575.0, "monoisotopic_mass": 92575.0 }, "refseq": { "ac": "XP_006251022", "name": "toll-like receptor 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006251022" }, "gene_names": [ { "name": "Tlr6", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9", "id": "A0A096MKA9" }, { "name": "Tlr6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006251022", "id": "XP_006251022" } ], "protein_names": [ { "name": "Toll-like receptor", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9/entry#names_and_taxonomy", "id": "A0A096MKA9" }, { "name": "toll-like receptor 6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006251022", "id": "XP_006251022" } ], "function": [], "disease": [ { "disease_id": "DOID:0060000", "recommended_name": { "id": "DOID:0060000", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060000", "name": "infective endocarditis", "description": "An endocarditis that is characterized by inflammation of the endocardium caused by infectious agents." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0060000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060000" } ] }, { "disease_id": "DOID:13564", "recommended_name": { "id": "DOID:13564", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:13564", "name": "aspergillosis", "description": "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system." }, "synonyms": [ { "id": "DOID:13564", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:13564", "name": "Infection due to Aspergillus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13564" } ] }, { "disease_id": "DOID:1574", "recommended_name": { "id": "DOID:1574", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences." }, "synonyms": [ { "id": "DOID:1574", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1574", "name": "Ethanol abuse", "description": "" }, { "id": "DOID:1574", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1574", "name": "alcohol abuse", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, bronchial", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, diminished response to Antileukotriene treatment 1N", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, protection against", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, susceptibility to", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma-related traits, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080819", "DOID:9360", "DOID:0080811" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:399", "recommended_name": { "id": "DOID:399", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes." }, "synonyms": [], "unlinked_id_list": [ "DOID:2149" ], "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ] }, { "disease_id": "DOID:4194", "recommended_name": { "id": "DOID:4194", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4194", "name": "glucose metabolism disease", "description": "A carbohydrate metabolic disorder that is characterized by blood glucose levels which cannot be maintained within the normal range." }, "synonyms": [ { "id": "DOID:4194", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4194", "name": "disorder of glucose metabolism", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4194", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4194" } ] }, { "disease_id": "DOID:4483", "recommended_name": { "id": "DOID:4483", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ] }, { "disease_id": "DOID:612", "recommended_name": { "id": "DOID:612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:612", "name": "primary immunodeficiency disease", "description": "An immune system disease that results when one or more essential parts of the immune system is missing or not working properly at birth due to a genetic mutation." }, "synonyms": [ { "id": "DOID:612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:612", "name": "hypoimmunity", "description": "" }, { "id": "DOID:612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:612", "name": "immune deficiency disorder", "description": "" }, { "id": "DOID:612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:612", "name": "immunodeficiency syndrome", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton-type agammaglobulinemia", "description": "X-linked agammaglobulinemia (XLA) is a clinically variable form of isolated agammaglobulinemia, an inherited immunodeficiency disorder, and is characterized in affected males by recurrent bacterial infections during infancy." }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "BTK deficiency", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "BTK-deficiency", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton agammaglobulinemia tyrosine kinase deficiency", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton type agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton's Sex-linked agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton's X-linked agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton's agammaglobulinaemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton's type agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton-type agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "X-linked agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "agammaglobulinemia, X-linked 1, X-linked recessive", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "Bruton's agammaglobulinemia", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "XLA", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "agammaglobulinemia, BTK", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "agammaglobulinemia, Bruton tyrosine kinase", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "agammaglobulinemia, X-linked", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "agammaglobulinemia, X-linked, type 1", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "hypogammaglobulinemia, X-linked", "description": "" }, { "id": "MONDO:0010421", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010421", "name": "immunodeficiency 1", "description": "" }, { "id": "MONDO:0009453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009453", "name": "obsolete immune deficiency disease", "description": "" }, { "id": "MONDO:0009453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009453", "name": "immune deficiency disease", "description": "" }, { "id": "MIM:300755", "resource": "MIM", "url": "https://www.omim.org/entry/300755", "name": "X-linked agammaglobulinemia", "description": "X-linked agammaglobulinemia" } ], "unlinked_id_list": [ "DOID:0111965", "DOID:0111963", "DOID:0111964", "DOID:0061170", "DOID:0051000", "DOID:11200", "DOID:0080709", "DOID:0080710", "DOID:0111966", "DOID:6025", "DOID:626" ], "evidence": [ { "id": "612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:612" } ] }, { "disease_id": "DOID:854", "recommended_name": { "id": "DOID:854", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:854", "name": "collagen disease", "description": "A connective tissue disease that characterized by connective tissue disease that has_material_basis_in inheritable defects in collagen." }, "synonyms": [ { "id": "DOID:854", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:854", "name": "collagen disorder", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:854" } ] }, { "disease_id": "DOID:8677", "recommended_name": { "id": "DOID:8677", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8677", "name": "perinatal necrotizing enterocolitis", "description": "" }, "synonyms": [ { "id": "DOID:8677", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8677", "name": "ENTEROCOLITIS NECROTIZING", "description": "" }, { "id": "DOID:8677", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8677", "name": "Necrotizing enterocolitis in fetus OR newborn", "description": "" }, { "id": "DOID:8677", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8677", "name": "Perinatal necrotising enterocolitis", "description": "" }, { "id": "DOID:8677", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8677", "name": "Pseudomembranous enterocolitis in newborn", "description": "" }, { "id": "DOID:8677", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8677", "name": "necrotizing enterocolitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8677" } ] }, { "disease_id": "DOID:874", "recommended_name": { "id": "DOID:874", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:874", "name": "bacterial pneumonia", "description": "A pneumonia involving inflammation of the lungs caused by bacteria." }, "synonyms": [ { "id": "DOID:874", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:874", "name": "Pneumonia due to other gram-negative bacteria", "description": "" }, { "id": "DOID:874", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:874", "name": "gram-negative pneumonia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:874" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A096MKA9", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Tlr6", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9", "locus": { "chromosome": "14", "start_pos": 43375685, "end_pos": 43362164, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000002161", "url": "https://www.ensembl.org/id/ENSRNOG00000002161" } ] } } ], "crossref": [ { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSRNOG00000002161", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000002161", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "305353", "url": "https://www.ncbi.nlm.nih.gov/gene/305353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SWNSLEY", "url": "https://omabrowser.org/oma/group/SWNSLEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24365:SF422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24365:SF422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-5686938", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5686938", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "XP_006251022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006251022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1303030", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1303030", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A096MKA9", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A096MKA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V695", "url": "https://www.uniprot.org/uniprotkb/G3V695", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V695-1", "url": "https://www.uniprot.org/uniprotkb/G3V695-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKSLWDSLCNMSQDREPIVESFHFVCTLALIVGSMTQFSDEFESVVDYSNKNLTHVPKDLSPSTKSLSLSQNSISDLQMSDISFLSELRVLRLSHNRIRRLDFGVFLLNRDLEYLDVSHNQLQNISCCPMVNLKHLDLSFNDFEVLPVYKEFGNLMKLSFLGLSAAKFRQLDLLPISHLHLSCVLLDLVNYQIKDGETESLQVPNTNVLHLVFHPNSLFSVQVNISVNALGCLQLSNIKLNDKNCQSLIIFLSELTRGPTLLNLTLQHIETNWKCFVRLLQFLWPRPVEYLNIYNLTITESISRETFIYVETVLKSLKIEHVTNQVFLFVKDALYSVFAEMNIRMLTLSDTPFIHMVCPEFPSTFAFLNFTQNVFTDSIFQGCSTLKRLETLILQRNGLKNLFKVALMTKTMSSLETLDVSLNSLNSHVYDRTCAWAESIRVLNLSSNVLSDSVFRCLPPKVKVLDLHNNRIVSIPKDVTHLQALQELNVASNFLTDLPGCGAFSSLSVLVIDHNSVSHPSSDFFQSCQNIRSITAGNNPFRCTCELREFVKNIGQASREVVEGWPDSYRCDYPDSIKGTPLQDFHMSPLSCDTILLTVTIGATLLLLAAIGASLCLYFDLPWYLRMLWQWTQTRHRARNIPLEELQRNLQFHAFVSYSEHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIIHFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPIQQNNIPSRYHKLRALMAQRTYLEWPIEKGKRGLFWANLRASFIMKLALVNENDVKT", "length": 806, "header": "tr|A0A096MKA9-1|A0A096MKA9_RAT Isoform 1 of Toll-like receptor OS=Rattus norvegicus OX=10116 GN=Tlr6 PE=3 SV=2 CANONICAL=A0A096MKA9-1" }, "isoforms": [ { "isoform_ac": "A0A096MKA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9/entry#A0A096MKA9-1", "sequence": { "sequence": "MVKSLWDSLCNMSQDREPIVESFHFVCTLALIVGSMTQFSDEFESVVDYSNKNLTHVPKDLSPSTKSLSLSQNSISDLQMSDISFLSELRVLRLSHNRIRRLDFGVFLLNRDLEYLDVSHNQLQNISCCPMVNLKHLDLSFNDFEVLPVYKEFGNLMKLSFLGLSAAKFRQLDLLPISHLHLSCVLLDLVNYQIKDGETESLQVPNTNVLHLVFHPNSLFSVQVNISVNALGCLQLSNIKLNDKNCQSLIIFLSELTRGPTLLNLTLQHIETNWKCFVRLLQFLWPRPVEYLNIYNLTITESISRETFIYVETVLKSLKIEHVTNQVFLFVKDALYSVFAEMNIRMLTLSDTPFIHMVCPEFPSTFAFLNFTQNVFTDSIFQGCSTLKRLETLILQRNGLKNLFKVALMTKTMSSLETLDVSLNSLNSHVYDRTCAWAESIRVLNLSSNVLSDSVFRCLPPKVKVLDLHNNRIVSIPKDVTHLQALQELNVASNFLTDLPGCGAFSSLSVLVIDHNSVSHPSSDFFQSCQNIRSITAGNNPFRCTCELREFVKNIGQASREVVEGWPDSYRCDYPDSIKGTPLQDFHMSPLSCDTILLTVTIGATLLLLAAIGASLCLYFDLPWYLRMLWQWTQTRHRARNIPLEELQRNLQFHAFVSYSEHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIIHFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPIQQNNIPSRYHKLRALMAQRTYLEWPIEKGKRGLFWANLRASFIMKLALVNENDVKT", "length": 806, "header": "tr|A0A096MKA9-1|A0A096MKA9_RAT Isoform 1 of Toll-like receptor OS=Rattus norvegicus OX=10116 GN=Tlr6 PE=3 SV=2 CANONICAL=A0A096MKA9-1" }, "locus": { "chromosome": "14", "start_pos": 43373333, "end_pos": 43370916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000076753.3", "url": "https://www.ensembl.org/id/ENSRNOT00000076753.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000068444.2", "url": "https://www.ensembl.org/id/ENSRNOP00000068444.2" } ] } }, { "isoform_ac": "G3V695-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9/entry#G3V695-1", "sequence": { "sequence": "MVKSLWDSLCNMSQDREPIVESFHFVCTLALIVGSMTQFSDEFESVVDYSNKNLTHVPKDLSPSTKSLSLSQNSISDLQMSDISFLSELRVLRLSHNRIRRLDFGVFLLNRDLEYLDVSHNQLQNISCCPMVNLKHLDLSFNDFEVLPVYKEFGNLMKLSFLGLSAAKFRQLDLLPISHLHLSCVLLDLVNYQIKDGETESLQVPNTNVLHLVFHPNSLFSVQVNISVNALGCLQLSNIKLNDKNCQSLIIFLSELTRGPTLLNLTLQHIETNWKCFVRLLQFLWPRPVEYLNIYNLTITESISRETFIYVETVLKSLKIEHVTNQVFLFVKDALYSVFAEMNIRMLTLSDTPFIHMVCPEFPSTFAFLNFTQNVFTDSIFQGCSTLKRLETLILQRNGLKNLFKVALMTKTMSSLETLDVSLNSLNSHVYDRTCAWAESIRVLNLSSNVLSDSVFRCLPPKVKVLDLHNNRIVSIPKDVTHLQALQELNVASNFLTDLPGCGAFSSLSVLVIDHNSVSHPSSDFFQSCQNIRSITAGNNPFRCTCELREFVKNIGQASREVVEGWPDSYRCDYPDSIKGTPLQDFHMSPLSCDTILLTVTIGATLLLLAAIGASLCLYFDLPWYLRMLWQWTQTRHRARNIPLEELQRNLQFHAFVSYSEHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIIHFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPIQQNNIPSRYHKLRALMAQRTYLEWPIEKGKNFENIKAATRTSPWEAEEDISLSLRLVWSTQ", "length": 811, "header": "tr|G3V695-1|G3V695_RAT Computationally mapped isoform of Toll-like receptor OS=Rattus norvegicus OX=10116 GN=Tlr6 PE=3 SV=2 CANONICAL=A0A096MKA9-1" }, "locus": { "chromosome": "14", "start_pos": 43375370, "end_pos": 43370916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000002933.6", "url": "https://www.ensembl.org/id/ENSRNOT00000002933.6" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000002933.5", "url": "https://www.ensembl.org/id/ENSRNOP00000002933.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-RNO-5686938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5686938", "resource": "Reactome", "description": "Regulation of TLR by endogenous ligand" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AFM9-1", "protein_name": "Toll-like receptor 10", "gene_name": "Tlr10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLISSIYTLYNIIMSTEAWAPRPTDERELISNYSNMALRKVPPDVTPATTILDLSYNLLYQFQSSDCHSFSKLRFLILCHNSIQQLDTKIFDLNKELSYLDLSYNRLQSITWSSLVDLRHLDLSFNDFDTLPACEEIGNMRHLETLGLSGAKIQRSDLQKIANLQFSTVFIGLNTLSHYEEGSLPVLNTTVLHIVLPMAANFWVLLCDGMKTSKVVEMSNIGGKSQFVSYETPRTLSVENTKASTLIFHKVDLLWDDLLHVFQFVWRTSVECFQIQDLTFGGMASRDHSSFDYSNTVMKAVILESIHFRIFFIPQNKIYLFFTQMDLENLTISDAQMPHLLFPSHPQSFQHLNFANNILTDDLFKNPIQMPYLKTLVLRGNQLETLSLVSLFANHTSLLHLDLSQNLLQHGNGEKCMWPDTLILLNLSSNKFDGSVFRCLPKSIQTLDLNNNKIRAVPKEIIYLKSLRELSIAFNFLTDLPGCDHFKQLSSLNIEMNLILSPSLDFFQSCQEVKTLNAGRNPFRCICEFRDFIWLEKHSKGLMSGWPDSYACEYPLSLKGTPLKDVYLPELACNTTLLIVTIVLVILVLGLVVAFCILKFDMLWYLRVLAQCIRTQHRIRKTVREERKRSIQFHAFISYAAHDSVWVKNELIPNLETEDGSVLLCLPERNFDPDRSIAENIISCTEKSYKSIFVLSPNFVQNGWCHNELYLAHHNPFRDNYDYIIPILLEPIPSYCVPTKFPKLKALLEKKVYLEWPKDRRKHGLFWANLRAAINVNLSDTRGRCELQTFTKPNADCQGSTISLVRTDSF", "length": 811 }, "evidence": [ { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1RKQ4-1", "protein_name": "Toll-like receptor 13", "gene_name": "tlr19.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFAFATNSNFLRFFWRIALGLSICNVVLTRITKRCITIEEHLLKQMPWTPHCLHYPGKGPYANCNITDLSTDLSQVGFEVRTLCVFGDITSIPAKAFSHLPSLEVLHIDGIRLERVQAGAFEGLPNLKYLSMLFSDDLYRLVKMDNRSFAGLNNLEELSLTGLMLLNGSSGIFDPLVSLIRLDIVRTCAQDLGEIFCCISNGMTRLRHLNVEDSEISTIENKGCAGGSMTWPLTALSGVQNLYLIGNNIKSIQANSLNIFQNLSSLFLEFEGKSLGSIWESGVGKVNDLTLKGKVLKKYSTNFKDLCHLVSSLYSQSLSLVYTSIDRLTAEDLKDCGTKLTKLLIQNSKIDNLDFRFWTSKLEMQALQMAYMKLTDAPFCFVANSTMWSLTSLDLTGNSITNIDGDQFACMPFLEQLYLSQNAIKTLQLHAFRGLLRLKILQLDSNKISQLSANDFKNLHALEVLLINDNIIETIETGTFWDQRELRELSFGRLEYVYELHLENIFFEFPPKLQRLSIDAHYGTHIYIGNASPPNGTFALELNGEKLSFADCKSDVLMAVRELKVNCTFFLCENLFMAPYFLNLESFEISGGAERAPLNYATINNLHHLKHLKLAGLNFPNYTESRSAFWNLTQLQTLVMVNCYLSFLTKSMFRDLTSLQLLRLYSDSPLILTDGVFGVLPVLKAFILDRVDFQCSCENGWLLDWADSTEKVQVIYLQKQQCVWHYQKLNFLATMEKLCQTDAQYICYVATASSISLLLSAAVGYRFARWPSLVLFFRLKGWMERRFGRRWNRRRRRMEDDYGEIEEMQYDAFVSFCSQDEAWVLGEMAPRLEDQGNPRLRLCLHNRDFEVGKDIMDNITDSIHNSQCTVCLISRRYLRSDWCGLEMRVATHRQLEEQKHRLILIFLQHISPFELSAFHRLAKLVRSRTYLDWPEDEGDREHFWDRLRRNIAEDSEAS", "length": 958 }, "evidence": [ { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B7X7-1", "protein_name": "Toll-like receptor 4", "gene_name": "tlr4ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAALKMGFYAISVFLICYYIANGEPCTRIIENLHYSCMGRNLSSIPSSIPSSVQTLDFSFNFFPQLKKTIFPVLSFLRVLDLSRCHIRQIENDAFYNVKNLTTLFLTGNPIIYFAPGCLNTLYNLQRLVLVDIGLESLQLNINNLTKLQELNVGTNYIQSMTLPPFMTTFKNFSLLDLHANNISIIRTNHTVVLREIGRNMTLILTWNPLLHIEPGAFKDVYLRQLDIRSAFVSFSAQKAALKALHGLNVKRLIFGKYREDNGFHFVDNDVLDGLCCFNFQEVSYYVLESAKTTIAIFRCMINATRITVKGGNIYEMETVHFHKTKELYLINNGLGTLPTKQLSHLHTLEKLEITHNSEPIFAEPFTDLPKLQYVDLSDNQLKIKHCCSTLLSGTPQINYLNLSLNSEISVDVGGFEGLDSLEILDFSYTRVVRIGYLSVLSNLKNLRYLDVSYSSVTFSNIFCFLGLSSLNVLKMAGNNFQGNVAKYVFNNLTLLEHLDMSFCHLVELHTSSFKYLQRLRHLNVKGNYLIKIDFLTHPNLKQLTSFYVEKNSITAIPLHVLKNLPMNLSEFDLSFNPIDCSCSQTDFMLWIINNQKVLKQPENILCKTISPNSDFRVTDFDIDHCVYKKKLIIVLPVFCVVFIVVLSILVYRFQFYLRYCWILLRGYRSPGQQECSYDAFVIFSSYDEAWVMNELMENLENGVPPIQLCLHMRDFQAGKSIASNIIDEGIMGSRKIIVVVSQHFIDSAWCRFEFELAQSRFLMERNANIIIIILEDVAERKTKKILGLHKHLKKNTYLKWSRDPLSNMRFWIRLRKAIVATKQ", "length": 824 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A3KH14-1", "protein_name": "Toll-like receptor 18", "gene_name": "tlr18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLVPLVLILSLQAVLHIKHAKAKQSCTIAFDKLSADCKGLRLDSVPTTQLPDSLEELDLSFNTIHVIRKQDFVKLTYLRVLKLNFNNISLVLDDAFQGNLLLEELNLFNNSLTEIPFKALEPLTNLKVLEMSNNLYSQASLGAAFLNFNQLKVLSIGGPLVSSLGSRDIYVLKNISLDKFAVKTGTGFRDYEPGYFKSLSTKHLWFDIAFDKNPDLLPKMLKDLANKTFDVLRFRNLFEFQYYTGKRDIFYGLQYVNAQTLTFYRGKFNEEVMRMALKNVEISPIKALELLLIDFARSQNRTQGSSVKNLSLDRLVLSDISNPDIMRFDWSFTWLNHVRKFIVWNVNFNSVPCDSWPEMKSVELLDISNNQLLDSYIYNPLCDTRNTLHKLDTFNVSHNRLTSLSDLASLTKDFVKLTTIDMSHNQLQYLGNGACDWRKTITKVIGNHNSLTSDSFKCLPTSVNFLDLSYSSLDQLDMDYFNKASELTELLLSGNKIKFIPSGWKNRYLRTLALDGNSFGLVSMKSFKDMLSLRVLTAGNNPYHCTCDLYTFIQETTSKGKVTITDWPNNYKCYHPERLLNTMVSKYSPGHLACDITLVIIISVSTTAAVVLVIMLLCYIFHVPWYVKATYQIIRAKYRAHKEGLGQGVDYAFHAFISYSHSDADWVRNHLLPCLENVKPPYRLCIHERDFIPGKWIIDNIIENIENSRKVIFVLSHNFVNSEWCNYELYFAQQRAIGKTFSDVILVVKEPIDPTSLPSKFCKLKRMLNTKTYLEWPQQPTEQNFFWIQLRSVLGKPNSIRPRTISRHSRLSSARSVSLIEAPQIQDPEGPDEEDHQNSPQPSNKCQLTCIEVA", "length": 854 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B3DIW3-1", "protein_name": "3.2.2.6", "gene_name": "tlr1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKPSSGWWLVSVYLTCFHPSLIPAIQRIIVNYSSQNLSSVPDDLKPSTEDLDLSLNHIQSLNCRDFNTTPRLRFLNLSWNILENIDRDTFTSTPALEMLDLSHNGLQNLSEQPYLLHLGCLELLDLSSNRFSAMALGEEFSMLKRLQWLGLSAKSISIQDFTHISNLTLRTLFINADGLLTYEGNSLDDVHAEKAVIALSSTNVDIAIANDVFARFKEVEFTKVDGKMEVVQQMRSRALMRTVRLEISNVKTTWEFLTSSVNTILSSTIRELSLTDLTLTEMKDGANQSSTHILESFSTKRASVTTFIFDQKMLYDFFINTPARKVSLTESPIIFMTCPGTISKIQELDLSDCALTEKIFSVNPETECGTLVNLTRLVLRGNNLKHLSPLTSRINLMDSLQYIDLSQNTLTYSENQGRCFWPPRVLHVDLSRNGFDEVVFKCLPDSVQVLNLRHNRVSTVPADIHTFDTLQVIDLTFNRLLDLPTCRSFPSLQKLLIRSNSIHSPVPGSLKTCQHLQDLDLSHNPFICTCALRDFASLINAQGIKTFKSTLKHWPDGYRCSYPESWSNSTLEDFYLPEISCNAWILAITILIPTISLIVAVSLLCNRLDIPWYVRMMWKWTRAKHYSITSQLKEEDVERLHFHAFVSYSQKNAGWVKSQFLPKLEGDCGLRMCHHERDFIPGKTVVQNILRCIEQSRRCVFVLSSHFVQSEWCHYELYFANHQKLTRGMDSILLILLEPLPLYLIPSKYYQLKTMMSRRTYLEWPQEGAKQKLFWANLRAALQAELPNTPDREEE", "length": 795 }, "evidence": [ { "id": "HGNC:16711", "url": "https://alliancegenome.org/gene/HGNC:16711#orthology", "database": "AGR" }, { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" }, { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PTD9-1", "protein_name": "Toll-like receptor 2", "gene_name": "Tlr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQALWLFWILMAVIGLSREGHSAQASLSCDAAGVCDGSSRSFTSIPSGLTANTKKLDLSFNKITYIGHGDLRACVNLRVLTLESSGINTIEGDAFYSLGSLEHLDLSNNHLSSLSSSWFRPLSSLKYLNLMGNPYRTLGETSLFSNLTNLQNLRVGNVDTFSEIRRIDFAGLTSLNELEIQVLSLGNYESRSLQSIRDIYHLTLHLSESAFLLGIFADILSSVRYLELRDTNLARFQFSELSVDEINSPMKKLAFRNADLTDKSFNELLKLLRYILELMEVEFDHCTLNGVGNFNPSESDVVRELGKVETVTIRSLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACEGGWPSLQSLVLSQNHLRSIRKTAEILLTLKNLTALDISKNSFQPMPDSCQWPGKMRFLNLSSTGIQAVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPEASLFPVLQVMKIRENAISTFSKDQLGSFPKLETLEAGDNHFICSCELLSFILERPALVHVLVDWPDSYLCDSPPRLHGQRLQDARPSVLECHQAALVSGVCCALLLLILLLGALCYHFHGLWYLRMMWAWLRAKRKPKKAPCRDLCYDAFVSYSEQDSYWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIEKKAIPQRFCKLRKIMNTKTYLEWPLDEGQREVFWANLRTAIKS", "length": 784 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PTL5-1", "protein_name": "Toll-like receptor 1", "gene_name": "Tlr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSSSLKHVYCHTMTKTQSTIFYCIVVLGLILIKIQLSEESELIIKRPNANLTRVPKDLPLQTTTLDVSQNNISELQTSDILLLSKLRVFIMSYNRLQYLNISVFKFNTELEYLDLSHNELRLISCHATADLKHLDLSFNAFDALPICKEFGNLSQLQFLGLSGSQIQNSSVQLIAHLNISKVLLVLGDTYGEKEDPKCLQHISTETLHIVFPSKREFHFLLDMSVSTAISLELSNIKCVLEDKNCSYFLGTLERLRKTQRLSNLTLNNVDTTWNSFINILQLVWHTPVKSFSISNVKLKGHFNFRRFHYSDTSLRALSIHQVVTDVFSFPQSNIYSIFSNMNIQSFTVSGTRMVHMLCPDQISPFLYLDFTDNLLTDIVFEDCRNLIRLKTLSLQKNQLKTLENIILMSMEMTSLQKLDISQNSLRYSDAGSPCSWTQSLLVLNLSSNMLTDSVFRCLPPKVKVLDLHNNRIVSISKDVTHLQALQELNVASNFLTDLPGCGAFSSLSVLVIDHNSVSHPSSDFFQSCQNIRSITAGNNPFRCTCELREFVKNIGQASREVVEGWPDSYRCDYPDSIKGTPLQDFHMSPLSCDTILLTVTIGATLLLLAAIGASLCLYFDLPWYLRMLWQWTQTRHRARNIPLEELQRNLQFHAFVSYSGHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIIHFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPIPQYSIPTNYHKLKTLMARRTYLEWPTEKSKHGLFWANLRASINVKLVNQAEATCYTQQ", "length": 808 }, "evidence": [ { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI", "length": 839 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKEIDRQTEQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSHCILNWPVQKERIGAFRHKLQVALGSKNSVH", "length": 904 }, "evidence": [ { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS", "length": 784 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08953-1", "protein_name": "Protein toll", "gene_name": "Tl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRLKAASELALLVIILQLLQWPGSEASFGRDACSEMSIDGLCQCAPIMSEYEIICPANAENPTFRLTIQPKDYVQIMCNLTDTTDYQQLPKKLRIGEVDRVQMRRCMLPGHTPIASILDYLGIVSPTTLIFESDNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAELQSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYNNISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQFKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKNMQLMELHLENNTLLRLPSANTPGYESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNRTMKWRSVKLSGNPWMCDCTAKPLLLFTQDNFERIGDRNEMMCVNAEMPTRMVELSTNDICPAEKGVFIALAVVIALTGLLAGFTAALYYKFQTEIKIWLYAHNLLLWFVTEEDLDKDKKFDAFISYSHKDQSFIEDYLVPQLEHGPQKFQLCVHERDWLVGGHIPENIMRSVADSRRTIIVLSQNFIKSEWARLEFRAAHRSALNEGRSRIIVIIYSDIGDVEKLDEELKAYLKMNTYLKWGDPWFWDKLRFALPHRRPVGNIGNGALIKTALKGSTDDKLELIKPSPVTPPLTTPPAEATKNPLVAQLNGVTPHQAIMIANGKNGLTNLYTPNGKSHGNGHINGAFIINTNAKQSDV", "length": 1097 }, "evidence": [ { "id": "HGNC:16711", "url": "https://alliancegenome.org/gene/HGNC:16711#orthology", "database": "AGR" }, { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" }, { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLDLSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDPEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKLQTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNIDQVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSLCSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLEKEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKLTEQAKK", "length": 786 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q32PW5-1", "protein_name": "Toll-like receptor 3", "gene_name": "tlr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLMKLILLPLFYACFSAHCAGTTNARKSACMIKNAKADCSHMNLDAIPTDLPTNITTLDVSHNRLKTLSSLHMYTNLVNIDASYNSLAGIEKDLCLSLPHLQFLNVQHNQVYLISEKNLKNCFHLTQLDLSDNKLKLQGEPFSLLKNLTWLDVSRNKLTSAKLGTEPQLPNLVTLVLSGNNINILQENDFSFLSNSSSFRVLILSSLILKKVENGCFKAIDTLSDLVLDSSKLTSQFTTSLFEELADTALRNLSLKSTEQVTLSNTTFQGLEKTKITVLDLSENRISKIVDGAFQWLPQLEFLSLEHNTIRHLTNDSFSGLGNLRQLNLRKALIKSHASLPVIDDFSFQHLVQLEYLCMANTAFRELTEQIFSGLRNLKTLDLSWSITGIKTVTNKTFAGLQESPLLQTLNLTGMGINKLEPGAFSSLGNLSNLLMSRNFINQQLQGNEFKGLSNIKEIDMSINQQSISLTNASFVHVSTLRTLKLGRALKGTLDMEPSPFRPLVNLTILDLSNNNIANINADLLEGLYNLKVVKMQHNNLARLWKMANPGGPVLFLKDATNLSYLNLDYNGIDEIPPNAFRGFSELHELSLRGNLLDQLHASVFDDLNSLKYLHLQKNLITSVQRATFGVPLSKLKELNMDHNPFDCTCESILWFSEWLNSTNTSVPGFPQSYICNTPNAYFNHSVMNFDPLSCKDMTPFKALYILSSTAVLMLLFISFLVHFQGWRIQFYWNIMVNRMLGSLKDAKVTEGRFQFDAYIIHAGEDKSWVERSLLSLEDKDLNFFYEQRDSTPGHSRLETIVDNMVYSRKIIFVITEMLLKDPWCRQFKAHHALHHVMEDNRDSLILIFLEDVTDYNLNRSLHLRRGMLKPKCVLYWPLHKERIPAFHQKLRSALASTNKVN", "length": 903 }, "evidence": [ { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q59HI6-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKDKEPTVISLHSVYVMTLVWGTLIQFSEESEFVVDKSKIGLTRVPKDLPPQTKVLDVSQNFITELHLSDISFLSQLTVLRLSQNRMQCLDISVFKFNQDLEYLDLSHNQLQTILCHPITSLKHLDLSFNDFEALPICKEFGNLTQLNFLGLSATKLQQLDLLPIAHLHLSCILLDLERYYMKENEKESLQILNTKKLHLVFHPNSFFSVQVNISVKSVGCLQLANIKLSDDNCQVFITFLLELTQGPTLLNFTLNHVETTWKCLVGIFQFLWPKPVEYLSIYNLTIVESIDEEDFIYYETTLKGVKIEHITKRVFIFSQTALYRVFSDMNIRMLTIADTHFIHMLCPQVPSTFNFLNFTQNVFTDSVFQNCKTLARLETLILQKNKLEDLFKISLMTKDMLSLEILDVSSNSLEYDRHGENCTWVGSIVVLNLSSNILTDSVFRCLPPRIKVLDLHSNRIRSIPKDVAHLEALQELNVASNSLAHLPGCGSFSSLSILTIDYNSISNPSADFFQSCQKIRSLKAGNNPFQCTCELRDFIQSLGQVSSDVVESWPDSYECEYPESYKGTLLKDFRVSELSCNTALLIVTIGVTGLALALTMTGLCVYFDLPWYLRMLCQWTQTRRRARNVPLEELQRTLQFHAFISYSEHDSAWVKNELVPCLEKEGIKICLHERNFVPGKSIMENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSDNLILILLDPIPQNSIPGKYHKLKALMAQRTYLEWPKEKSKHGLFWANIRAAFNIKLKLVAEEDDVKT", "length": 796 }, "evidence": [ { "id": "A0A096MKA9", "url": "https://omabrowser.org/oma/group/A0A096MKA9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6R5P0-1", "protein_name": "Toll-like receptor 11", "gene_name": "Tlr11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRMERHQFCSVLLILILLTLVSLTLTGWAWTIPDCIIADSLLFPNLSYYIPFCTSAPGLHLLASCSNVKNLNQTLKRVPRNTEVLCLQGMVPTLPAKAFIRFHSLQLLRLQLRTTSVTSRTFQGLDQLQYLFFDHHAPCCLSLFLSPNCFESLRSLSSLSFQGYCLTYSQSIYLPTSLRHLTLRNSCLTKFQDLQRLFPDLLLSTSSTPNIKPGAPFLETLDLSYNLQLKQAGVRDLYGLTLHSLILDGTPLKALDLTDSGLLHLHFLSLVGTGIEKVPASLTGYSELRALDLGKNQIQNILENGEIPGYKALEFLSLHDNHLQTLPTRFLHTLPQLQKLNLSMNKLGPILELPEGLFSTNLKVLDLSYNQLCDVPHGALSLLSQLQELWLSGNNISSLSNESLQGLRQLRTLDLSWNQIKVLKPGWLSHLPALTTLNLLGTYLEYILGIQLQGPKMLRHLQLGSYPILDIYPPWPPTLLSLEIQAESCIQFMIHSGQPFLFLENLTLETSILLLKPDNITIHFPSLRRLTLRGYSFIFSTSQLQRFFPQQLPLLEHFFIWCENSYAVDLYLFGMPRLRVLELGYLNFFYESSTMKLEMLLKEVPQLQVLALSHLNLRNLSVSSFKSLQDLKLLLFNSERALEMNSNLQEFIPQMPQYVYFSDVTFTCQCEASWLESWATRAPNTFVYGLEKSICIANASDYSKTLLFSFLATNCPHGTEFWGFLTSFILLLLLIILPLISCPKWSWLHHLWTLFHTCWWKLCGHRLRGQFNYDVFISYCEEDQAWVLEELVPVLEKAPPEGEGLRLCLPARDFGIGNDRMESMIASMGKSRATLCVLTGQALASPWCNLELRLATYHLVARPGTTHLLLLFLEPLDRQRLHSYHRLSRWLQKEDYFDLSQGKVEWNSFCEQLKRRLSKAGQERD", "length": 926 }, "evidence": [ { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXR5-1", "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVLATREMYELQTFTELNEESRGSTISLMRTDCL", "length": 811 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPQ1-1", "protein_name": "Toll-like receptor 1", "gene_name": "Tlr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKPNSLIFYCIIVLGLTLMKIQLSEECELIIKRPNANLTRVPKDLPLQTTTLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQYLNISVFKFNTELEYLDLSHNELKVILCHPTVSLKHLDLSFNAFDALPICKEFGNMSQLQFLGLSGSRVQSSSVQLIAHLNISKVLLVLGDAYGEKEDPESLRHVSTETLHIVFPSKREFRFLLDVSVSTTIGLELSNIKCVLEDQGCSYFLRALSKLGKNLKLSNLTLNNVETTWNSFINILQIVWHTPVKYFSISNVKLQGQLAFRMFNYSDTSLKALSIHQVVTDVFSFPQSYIYSIFANMNIQNFTMSGTHMVHMLCPSQVSPFLHVDFTDNLLTDMVFKDCRNLVRLKTLSLQKNQLKNLENIILTSAKMTSLQKLDISQNSLRYSDGGIPCAWTQSLLVLNLSSNMLTGSVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQNIRSLTAGNNPFQCTCELRDFVKNIGWVAREVVEGWPDSYRCDYPESSRGTALRDFHMSPLSCDTVLLTVTIGATMLVLAVTGAFLCLYFDLPWYVRMLCQWTQTRHRARHIPLEELQRNLQFHAFVSYSGHDSAWVKNELLPNLEKDDIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLAPIPQYSIPTNYHKLKTLMSRRTYLEWPTEKNKHGLFWANLRASINVKLVNQAEGTCYTQQ", "length": 795 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPW9-1", "protein_name": "Toll-like receptor 6", "gene_name": "Tlr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQDRKPIVGSFHFVCALALIVGSMTPFSNELESMVDYSNRNLTHVPKDLPPRTKALSLSQNSISELRMPDISFLSELRVLRLSHNRIRSLDFHVFLFNQDLEYLDVSHNRLQNISCCPMASLRHLDLSFNDFDVLPVCKEFGNLTKLTFLGLSAAKFRQLDLLPVAHLHLSCILLDLVSYHIKGGETESLQIPNTTVLHLVFHPNSLFSVQVNMSVNALGHLQLSNIKLNDENCQRLMTFLSELTRGPTLLNVTLQHIETTWKCSVKLFQFFWPRPVEYLNIYNLTITERIDREEFTYSETALKSLMIEHVKNQVFLFSKEALYSVFAEMNIKMLSISDTPFIHMVCPPSPSSFTFLNFTQNVFTDSVFQGCSTLKRLQTLILQRNGLKNFFKVALMTKNMSSLETLDVSLNSLNSHAYDRTCAWAESILVLNLSSNMLTGSVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQNIRSLTAGNNPFQCTCELRDFVKNIGWVAREVVEGWPDSYRCDYPESSKGTALRDFHMSPLSCDTVLLTVTIGATMLVLAVTGAFLCLYFDLPWYVRMLCQWTQTRHRARHIPLEELQRNLQFHAFVSYSEHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIINFIEKSYKAIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPILQNNIPSRYHKLRALMAQRTYLEWPTEKGKRGLFWANLRASFIMKLALVNEDDVKT", "length": 795 }, "evidence": [ { "id": "HGNC:16711", "url": "https://alliancegenome.org/gene/HGNC:16711#orthology", "database": "AGR" }, { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" }, { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030#orthology", "database": "AGR" }, { "id": "A0A096MKA9", "url": "https://omabrowser.org/oma/group/A0A096MKA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLF7-1", "protein_name": "Toll-like receptor 5", "gene_name": "Tlr5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACQLDLLIGVIFMASPVLVISPCSSDGRIAFFRGCNLTQIPWILNTTTERLLLSFNYISMVVATSFPLLERLQLLELGTQYANLTIGPGAFRNLPNLRILDLGQSQIEVLNRDAFQGLPHLLELRLFSCGLSSAVLSDGYFRNLYSLARLDLSGNQIHSLRLHSSFRELNSLSDVNFAFNQIFTICEDELEPLQGKTLSFFGLKLTKLFSRVSVGWETCRNPFRGVRLETLDLSENGWTVDITRNFSNIIQGSQISSLILKHHIMGPGFGFQNIRDPDQSTFASLARSSVLQLDLSHGFIFSLNPRLFGTLKDLKMLNLAFNKINKIGENAFYGLDSLQVLNLSYNLLGELYNSNFYGLPRVAYVDLQRNHIGIIQDQTFRLLKTLQTLDLRDNALKAIGFIPSIQMVLLGGNKLVHLPHIHFTANFLELSENRLENLSDLYFLLRVPQLQFLILNQNRLSSCKAAHTPSENPSLEQLFLTENMLQLAWETGLCWDVFQGLSRLQILYLSNNYLNFLPPGIFNDLVALRMLSLSANKLTVLSPGSLPANLEILDISRNQLLCPDPALFSSLRVLDITHNEFVCNCELSTFISWLNQTNVTLFGSPADVYCMYPNSLLGGSLYNISTEDCDEEEAMRSLKFSLFILCTVTLTLFLVITLVVIKFRGICFLCYKTIQKLVFKDKVWSLEPGAYRYDAYFCFSSKDFEWAQNALLKHLDAHYSSRNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEAFRYAQSRSLSDLKSILIVVVVGSLSQYQLMRHETIRGFLQKQQYLRWPEDLQDVGWFLDKLSGCILKEEKGKKRSSSIQLRTIATIS", "length": 859 }, "evidence": [ { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QUK6-1", "protein_name": "Toll-like receptor 4", "gene_name": "Tlr4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT", "length": 835 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QUN7-1", "protein_name": "Toll-like receptor 2", "gene_name": "Tlr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRALWLFWILVAITVLFSKRCSAQESLSCDASGVCDGRSRSFTSIPSGLTAAMKSLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLSSLSSSWFGPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLELRDTNLARFQFSPLPVDEVSSPMKKLAFRGSVLTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVTIRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPDASLFPVLLVMKIRENAVSTFSKDQLGSFPKLETLEAGDNHFVCSCELLSFTMETPALAQILVDWPDSYLCDSPPRLHGHRLQDARPSVLECHQAALVSGVCCALLLLILLVGALCHHFHGLWYLRMMWAWLQAKRKPKKAPCRDVCYDAFVSYSEQDSHWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIERKAIPQRFCKLRKIMNTKTYLEWPLDEGQQEVFWVNLRTAIKS", "length": 784 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QX05-1", "protein_name": "Toll-like receptor 4", "gene_name": "Tlr4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPLLHLAGTLIMALFLSCLRPGSLNPCIEVLPNITYQCMDQNLSKIPHDIPYSTKNLDLSFNPLKILRSYSFTNFSQLQWLDLSRCEIETIEDKAWHGLNQLSTLVLTGNPIKSFSPGSFSGLTNLENLVAVETKMTSLEGFHIGQLISLKKLNVAHNLIHSFKLPEYFSNLTNLEHVDLSYNYIQTISVKDLQFLRENPQVNLSLDLSLNPIDSIQAQAFQGIRLHELTLRSNFNSSNVLKMCLQNMTGLHVHRLILGEFKNERNLESFDRSVMEGLCNVSIDEFRLTYINHFSDDIYNLNCLANISAMSFTGVHIKHIADVPRHFKWQSLSIIRCHLKPFPKLSLPFLKSWTLTTNREDISFGQLALPSLRYLDLSRNAMSFRGCCSYSDFGTNNLKYLDLSFNGVILMSANFMGLEELEYLDFQHSTLKKVTEFSVFLSLEKLLYLDISYTNTKIDFDGIFLGLISLNTLKMAGNSFKDNTLSNVFTNTTNLTFLDLSKCQLEQISRGVFDTLYRLQLLNMSHNNLLFLDPSHYKQLYSLRTLDCSFNRIETSKGILQHFPKSLAVFNLTNNSVACICEYQNFLQWVKDQKMFLVNVEQMKCASPIDMKASLVLDFTNSTCYIYKTIISVSVVSVLVVATVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFQLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNALGRHIFWRRLKKALLDGKALNPDETSEEEQEATTLT", "length": 835 }, "evidence": [ { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VIA4-1", "protein_name": "MstProx", "gene_name": "MstProx", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLLTIPDDYCETYCGGICNDTVASKTCDREAYDYIATNEYHLIMRDGHLEVNWKIPDPNIFIISPISKENRLKLNELIVSDTSYPIRAVDYLRQLGVETVTRFENQINSFKVIERDVHYINGPKSLKIIIQSNLYLNEIIEYINKTTDNVNEIIINAYKTVENQQIALDNLIFNGKSHLRSLTFIGFQIENLSTKPFAQFINLKRMVLTNCTVRNLTFLRTLQKSLEHLELDIDNEVDLKYFTNFSSLKFMKVRNYIPNKNFTALICTHKNCNFIRGINGLECPKLCQCLYIIDDLELNIDCSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSRNRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTIHCDDKPLLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGFLKFLGKHFIWLGVRKQEYYLINEEQLLQSMHRKLNNLNTIMSIYKYMEWLHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCRNKFVYNFPDIVARNSRLMGKQNMSSPMELHLSKNNISNITIAMLPKELRFLDLRFNNLVTLDDKVLSYLKKNSIKTKLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNISPTDCPDVCVCCLDNLTWPSFIVDCRGEGLLQMPSLSSRVTYVDLRNNNLTALSQKNRSSIENRSLKLHLLDNPWSCSCNDIEKINFMKSVSSSIVDFTEIKCSNGEKLVSINQHIVCPSDLFYYLALAISLVATIIALNFLIWFRQPVLVWFYEHGVCLSLSAKRELDKDKRFDAFLAFTHKDEALLEEFVDRLERGRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLALHATSRDRCKRLIVVLYPNVKNFDSLDSELRTYMAFNTYLERSHPNFWNKLIYSMPLLPSYVD", "length": 965 }, "evidence": [ { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJX9-1", "protein_name": "Tehao, isoform B", "gene_name": "Tehao", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTYLPVVWLFFALLVLRSATGQIIPLPTFCLGLSPQCTCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYASTELQWLPRFNISSLVKIEFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPENITTWHFGSVPGLKKFKFFSHVPELQESIFHGFDTLRDLHLSVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRLASATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSSTIFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKWGDPLFWSKLYYAMPHNRRVLKGQKKHAGPLI", "length": 795 }, "evidence": [ { "id": "HGNC:16711", "url": "https://alliancegenome.org/gene/HGNC:16711#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" }, { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLE6-1", "protein_name": "Toll-4", "gene_name": "Toll-4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEHSKLWDLRPEVRERRFKWTSDGQQQQQQQLGWCNNKDDPPNSHQKSKSNNDARNLNSRVRVRARVRVVPGEMRMGDINCSNGLGNIREDYCEIYLDELGENGTCSIANNEVTTEDYQMKLVFLKLEINWTSPVFHGWNIFKICNETDYELVIISVLGIRSEVDMRISPAVQYLSLLGIREISGYDIYLPSVLITEMDVHHANGPKMVTFKYLYDSTVNSVITNNYIRKTMNNTEKIKIYYHNTFEKTTLTMEKNIFHGKNKMSALIFNGLKIKGLTNNTFENLTSLNTLIFDNVFLKDLSFLRSSTLQSSLTYCIMKVDNMVDLKSFEKFTNLEIIEVSQYKGFKNFTAFICEPYKSHCKFTLGINEVACPLKCNCSYNRDKSQLEIDCWQKNLTTIPSLPVPKKGSSALVFQSNLLAELPDNSLEGYHNLKSLDVSYNQLTSLSVSQLPESLHYLDIRHNKITTLSPQVVEYLYSVNVFNQYGNKWSIYCDEYHLQEFFWYKAKLLRIKTSKFQTIMEYIELSSKGSFVENFFVQNIDQLYLEANEDEIIDAFGPSDKYFNLKLMEALNHAIWLFSGEFDEIILHHLNSPCPYRCSCCFEWHTGEFLINCRNLSLDIYPRLPNSIPYKTTLYLDRNEIRKLTNTESLVVAGHASIHKLHMSQNLLRELPLHLLPENITYLDVRNNLLKYLDDGVIAFLEYRENITKIELSGNPWECNCKAKAFLSFLRRHEPMEYETVLRRVEITDDKCPEDCICCVDTSNSDSLAYVVDCSGKELSEIPQLPTPTYGQTTLVFERNSLKKWPSSLLPGYSSVTRFYLAHNRLSDIDQLPDKLEYLDISNNNFSALDDRVRGFLQKRMNSSQLQLSLFGNPWTCRCEDKDFLVFVKEQAKNIANASAIQCIDTGRSLIEVEETDICPSVLIYYTSLAVSLLIIALSINVFICFRQPIMIWFYEHEICLSLAARRELDEDKKYDAFLSFTHKDEDLIEEFVDRLENGRHKFRLCFYLRDWLVGESIPDCINQSVKGSRRIIILMTKNFLKSTWGRLEFRLALHATSRDRCKRLIVVLYPDVEHFDDLDSELRAYMVLNTYLDRNNPNFWNKLMYSMPHASHLKRSRSDAETKV", "length": 1125 }, "evidence": [ { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPH1-1", "protein_name": "Toll-9, isoform A", "gene_name": "Toll-9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCPKYIWDVIVLVCLFLGNVREAYTEFSIQDGLIIEPDSATTSSEEAEEVSKERTDLKSLMLKYESDDGNSCLLDLIKDEVIWWQFPNGTLRDSTKKYAHKLYLDLSHGNLKDDSDLFREAKLSRKVTIWRTEVFSAAFNTLTAAPFRTLYSMRESLKLLSLRGNNFAELIPDAEDFARFVNESRLEASNSVPHHCELLLLHNTTDLYDRECYLYFNNNTNMGQSITTGRNYTNFIKVLKDRFDQHGSSSQSIAWATFPKMPRLVELDISNCSIEYVSKEAFRNVSNLRRLFMSDNKIMTISHDTFYYVQGVQYLDLSFTNFLTYSYQLQLPTLEMALSLIYGLKIQQNVFKYLPELIYLDLSHSKMTRNSAVAFAHLGDKLKFLSLCYTAIPMVSSTIFKNTVLEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYFERSNIKDLEWSKSLKNLQVLGLAGNNINALTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSNEMLKDFERLDYLSLGDNDFICDCHLRAVVEVAAANNKDADCSYRLLNYSQNAVGEEVISLAESLIIDRKLWQSRYIPWLQRSYSNIREFNRANHIIKLRFSSEDYMVAKCSAAQPYHLGDLDGDLTLKFQLLDYEASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTVIAVMGSLVGACILGFIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIFISYCQNDRTWVLNELLPNVEETGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFEMYLAQHRIFEVSKEHLILVFLEDIPRRKRPKTLQYLMDVKTYIKWPTAKEDRKLFWKRLKRSLEVIGINSREISV", "length": 900 }, "evidence": [ { "id": "HGNC:16711", "url": "https://alliancegenome.org/gene/HGNC:16711#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKDKEPIVKSFHFVCLMIIIVGTRIQFSDGNEFAVDKSKRGLIHVPKDLPLKTKVLDMSQNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKISCHPIVSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSAMKLQKLDLLPIAHLHLSYILLDLRNYYIKENETESLQILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLNFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESGRHKENCTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELREFVKNIDQVSSEVLEGWPDSYKCDYPESYRGSPLKDFHMSELSCNITLLIVTIGATMLVLAVTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSEHDSAWVKSELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQRTYLQWPKEKSKRGLFWANIRAAFNMKLTLVTENNDVKS", "length": 796 }, "evidence": [ { "id": "HGNC:16711", "url": "https://alliancegenome.org/gene/HGNC:16711#orthology", "database": "AGR" }, { "id": "FB:FBgn0262473", "url": "https://alliancegenome.org/gene/FB:FBgn0262473#orthology", "database": "AGR" }, { "id": "FB:FBgn0036978", "url": "https://alliancegenome.org/gene/FB:FBgn0036978#orthology", "database": "AGR" }, { "id": "FB:FBgn0026760", "url": "https://alliancegenome.org/gene/FB:FBgn0026760#orthology", "database": "AGR" }, { "id": "MGI:1341296", "url": "https://alliancegenome.org/gene/MGI:1341296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040220-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040220-1#orthology", "database": "AGR" }, { "id": "RGD:1303030", "url": "https://alliancegenome.org/gene/RGD:1303030#orthology", "database": "AGR" }, { "id": "A0A096MKA9", "url": "https://omabrowser.org/oma/group/A0A096MKA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 27, "go_terms": [ { "name": "nitric oxide metabolic process", "id": "GO:0046209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046209", "evidence": [ { "database": "UniProtKB", "id": "A0A096MKA9", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9" } ], "pmid": "" }, { "name": "positive regulation of macrophage activation", "id": "GO:0043032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043032", "evidence": [ { "database": "UniProtKB", "id": "A0A096MKA9", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor 2 signaling pathway", "id": "GO:0034136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034136", "evidence": [ { "database": "UniProtKB", "id": "A0A096MKA9", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9" } ], "pmid": "" }, { "name": "detection of diacyl bacterial lipopeptide", "id": "GO:0042496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042496", "evidence": [ { "database": "UniProtKB", "id": "A0A096MKA9", "url": "https://www.uniprot.org/uniprotkb/A0A096MKA9" } ], "pmid": "" }, 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