{ "uniprot_canonical_ac": "A0A087WSD2-1", "uniprot_ac": "A0A087WSD2", "uniprot_id": "A0A087WSD2_MOUSE", "mass": { "chemical_mass": 137566.0, "monoisotopic_mass": 137566.0 }, "refseq": { "ac": "NP_001363974", "name": "membrane-spanning 4-domains subfamily A member 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974" }, "gene_names": [ { "name": "Ms4a14", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2", "id": "A0A087WSD2" }, { "name": "Gm1276; SP3111", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974", "id": "NP_001363974" }, { "name": "Ms4a14", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974", "id": "NP_001363974" } ], "protein_names": [ { "name": "Membrane-spanning 4-domains, subfamily A, member 14", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2/entry#names_and_taxonomy", "id": "A0A087WSD2" }, { "name": "membrane-spanning 4-domains subfamily A member 14", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974", "id": "NP_001363974" } ], "function": [ { "annotation": "Blocking SP3111 with anti-SP3111 antibodies remarkably affected fertilization and early embryo development in mice. [SP3111]", "evidence": [ { "database": "RefSeq", "id": "NP_001363974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974" }, { "database": "PubMed", "id": "20180398", "url": "https://glygen.org/publication/PubMed/20180398" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs30518355", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30518355" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 249, "end_pos": 249, "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (ISS->NSS).", "chr_id": "19", "chr_pos": "11281811", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I249", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A087WSD2", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Ms4a14", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2", "locus": { "chromosome": "19", "start_pos": 11278613, "end_pos": 11291818, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000099398", "url": "https://www.ensembl.org/id/ENSMUSG00000099398" } ] } } ], "crossref": [ { "id": "MGI:2686122", "url": "https://alliancegenome.org/gene/MGI:2686122", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A087WSD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A087WSD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSMUSG00000099398", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000099398", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "383435", "url": "https://www.ncbi.nlm.nih.gov/gene/383435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "2686122", "url": "http://www.informatics.jax.org/marker/MGI:2686122", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "HSIESHI", "url": "https://omabrowser.org/oma/group/HSIESHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A087WSD2", "url": "https://www.orthodb.org/?gene=A0A087WSD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04103", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001363974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A087WSD2", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPSEEKRRNHVITIDPNETVLTAYPYRPHSSLLDFLKGEPKLLGAIQILLSLVIVGFGNILALNFTFSSKEFPLVILTGYPFWGAVIFLLTGLVTMSHDKPRRILKQGVTTMNVLSSLTALAGIALTLLSFTQQHRVCQTPSLEGPCVVGETLLLGILSVLLIITIVELSISVTVVSLRSRCWTSPREAVFFFPSEGAQNTEHPAPEENNTLQFEFQEKSSKDNTASSIKSVFLGGYAFFKLRVSRISSTPKTIQQKSDKGTSFMYVPEEQEATPPLSPEQEIKLNALPPPLTPYPSENIPSQKDSTTDHLNDADLSSIIHQTSDMQSNLLDYENASVTRFKTPSSHNSLHFSPANLSSQSLMASLSTQVLQYKQPSFHISQSYDLISEYFLSENIPFQDNQSQDTPSQYTPSQDIQFQDMLAQDISFQEIQSQESPNQDVLYQETPPQETPSQGTPYQDLPYQVLLIKDTSPQGTPYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPSQDSQYKETPSQEIFFQDTPFQNTPSQNIQYQDILSQDKISQGSQTQNSVSQEMASSDLQVLNTQVQIQQYPEVFYRDIRTEVMELTQEWKSNQGKKPTRRLSLSLPGKHGQVHPKRYSVDLQVKSEKPRRYSEDLQSKTSRRKSIDQQIKAWISPKKNTTEKQDAYTQTTDQLPHQQAEDQQTEDQQAQDQQADDQQAKEEVPVQQSQDEQIKDQKSIENLLPEEHPNDREDEGQQSDKEQPPEEQAQVQPVEDQQPKEQKAPNTQLQNWQGGQVLVKRAPRQLCDNWETQSFQFTEKSCSFWSTPSWQPISQRSQDWISQGWRNKDWKAQEWQFEVKPSLDWESQELLERESLRQRALYQQIQPQTTIVHQTPGHQLQNYIFQVGLCQGSRQQDSESGVLIEDVNEDDVQSREREPENTEETCQKPTDQQSEDMRPDNYPVSCQSLVPYTYVTCLSNIASEQEVQNNTPCSGSSKDLNTTSSTSYQRDQQQSEDSD", "length": 1232, "header": "tr|A0A087WSD2-1|A0A087WSD2_MOUSE Isoform 1 of Membrane-spanning 4-domains, subfamily A, member 14 OS=Mus musculus OX=10090 GN=Ms4a14 PE=1 SV=1 CANONICAL=A0A087WSD2-1" }, "isoforms": [ { "isoform_ac": "A0A087WSD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2/entry#A0A087WSD2-1", "sequence": { "sequence": "MESPSEEKRRNHVITIDPNETVLTAYPYRPHSSLLDFLKGEPKLLGAIQILLSLVIVGFGNILALNFTFSSKEFPLVILTGYPFWGAVIFLLTGLVTMSHDKPRRILKQGVTTMNVLSSLTALAGIALTLLSFTQQHRVCQTPSLEGPCVVGETLLLGILSVLLIITIVELSISVTVVSLRSRCWTSPREAVFFFPSEGAQNTEHPAPEENNTLQFEFQEKSSKDNTASSIKSVFLGGYAFFKLRVSRISSTPKTIQQKSDKGTSFMYVPEEQEATPPLSPEQEIKLNALPPPLTPYPSENIPSQKDSTTDHLNDADLSSIIHQTSDMQSNLLDYENASVTRFKTPSSHNSLHFSPANLSSQSLMASLSTQVLQYKQPSFHISQSYDLISEYFLSENIPFQDNQSQDTPSQYTPSQDIQFQDMLAQDISFQEIQSQESPNQDVLYQETPPQETPSQGTPYQDLPYQVLLIKDTSPQGTPYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPSQDSQYKETPSQEIFFQDTPFQNTPSQNIQYQDILSQDKISQGSQTQNSVSQEMASSDLQVLNTQVQIQQYPEVFYRDIRTEVMELTQEWKSNQGKKPTRRLSLSLPGKHGQVHPKRYSVDLQVKSEKPRRYSEDLQSKTSRRKSIDQQIKAWISPKKNTTEKQDAYTQTTDQLPHQQAEDQQTEDQQAQDQQADDQQAKEEVPVQQSQDEQIKDQKSIENLLPEEHPNDREDEGQQSDKEQPPEEQAQVQPVEDQQPKEQKAPNTQLQNWQGGQVLVKRAPRQLCDNWETQSFQFTEKSCSFWSTPSWQPISQRSQDWISQGWRNKDWKAQEWQFEVKPSLDWESQELLERESLRQRALYQQIQPQTTIVHQTPGHQLQNYIFQVGLCQGSRQQDSESGVLIEDVNEDDVQSREREPENTEETCQKPTDQQSEDMRPDNYPVSCQSLVPYTYVTCLSNIASEQEVQNNTPCSGSSKDLNTTSSTSYQRDQQQSEDSD", "length": 1232, "header": "tr|A0A087WSD2-1|A0A087WSD2_MOUSE Isoform 1 of Membrane-spanning 4-domains, subfamily A, member 14 OS=Mus musculus OX=10090 GN=Ms4a14 PE=1 SV=1 CANONICAL=A0A087WSD2-1" }, "locus": { "chromosome": "19", "start_pos": 11291697, "end_pos": 11278861, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000187467.2", "url": "https://www.ensembl.org/id/ENSMUST00000187467.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140996.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140996.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 1040, "start_aa": "Thr", "end_pos": 1040, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1040", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 528, "start_aa": "Thr", "end_pos": 528, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr528", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 533, "start_aa": "Thr", "end_pos": 533, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr533", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 538, "start_aa": "Thr", "end_pos": 538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr538", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 553, "start_aa": "Thr", "end_pos": 553, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr553", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 563, "start_aa": "Thr", "end_pos": 563, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr563", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 568, "start_aa": "Thr", "end_pos": 568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 583, "start_aa": "Thr", "end_pos": 583, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr583", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 588, "start_aa": "Thr", "end_pos": 588, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr588", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 598, "start_aa": "Thr", "end_pos": 598, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr598", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 618, "start_aa": "Thr", "end_pos": 618, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr618", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 638, "start_aa": "Thr", "end_pos": 638, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr638", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 643, "start_aa": "Thr", "end_pos": 643, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr643", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 648, "start_aa": "Thr", "end_pos": 648, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr648", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 658, "start_aa": "Thr", "end_pos": 658, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr658", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 663, "start_aa": "Thr", "end_pos": 663, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr663", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 678, "start_aa": "Thr", "end_pos": 678, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr678", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 683, "start_aa": "Thr", "end_pos": 683, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr683", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 688, "start_aa": "Thr", "end_pos": 688, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr688", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.0.xxxxx" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "[Role of SP3111 protein in fertilization and early embryo development in mice].", "journal": "Zhonghua nan ke xue = National journal of andrology", "date": "2010-01", "authors": "Jia Xiao-Feng, Zhou Mi, Lin Ju-Fang, Shi Wei-Li, Zhang Xiao-Dong, Shi Hui-Juan", "evidence": [ { "database": "RefSeq", "id": "NP_001363974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001363974" } ], "reference": [ { "type": "PubMed", "id": "20180398", "url": "https://glygen.org/publication/PubMed/20180398" } ] }, { "title": "Modernizing reference genome assemblies.", "journal": "PLoS Biol.", "date": "2011", "authors": "Church Deanna M, Schneider Valerie A, Graves Tina, Auger Katherine, Cunningham Fiona, Bouk Nathan, Chen Hsiu-Chuan, Agarwala Richa, McLaren William M, Ritchie Graham R S, Albracht Derek, Kremitzki Milinn, Rock Susan, Kotkiewicz Holland, Kremitzki Colin, Wollam Aye, Trani Lee, Fulton Lucinda, Fulton Robert, Matthews Lucy, Whitehead Siobhan, Chow Will, Torrance James, Dunn Matthew, Harden Glenn, Threadgold Glen, Wood Jonathan, Collins Joanna, Heath Paul, Griffiths Guy, Pelan Sarah, Grafham Darren, Eichler Evan E, Weinstock George, Mardis Elaine R, Wilson Richard K, Howe Kerstin, Flicek Paul, Hubbard Tim", "evidence": [ { "database": "UniProtKB", "id": "A0A087WSD2", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2" } ], "reference": [ { "type": "PubMed", "id": "21750661", "url": "https://glygen.org/publication/PubMed/21750661" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A087WRT7-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 4A", "gene_name": "Ms4a4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLVIQGTEQSALEAGYGAQQNGQPLYVNSHSWKRMTEKFLKGEPKILGIVQIVIAIMNLSIGIMMIIATVSTGEIPPSSVYIGYPIWGSLMFIISGSFSIVAGRRTTKGLVRSSLGLNITSSVFAFSGIVISSLSPGIYSFHVYYCTYRGSSEGCHMTLSILMGLDIVVVVLSVLEFCIGVSLSAFGCRVMCCNPGGVMIIMPSNPTKAETANPVTLQSGLMPPEHQERNVPENMH", "length": 236 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSB9-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 12", "gene_name": "Ms4a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSSQTTYPGTRGIPNPCPPTRSMAPHPPQPLNFLNVRNQVQTGQVSFITSPGIFPNTQLGRENVPTVNPALGAAISNVKDAAIALGGVQITIGLMHIGFGVVLGLLSTSYNMTWAFSSVAFIGGYPFWGGVFFIASGSLSISAFKEFSHCLMKSTLIINISSTIFAFVGVILFLCDLNINGYYYQDYWMVLSGRGIAGVLAIFSLLEFSIAGAMAYFAHQGILRCNRSVPVAPAVYVANPLMRESPSAPPIYDNIPDYATTQ", "length": 263 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZDZ2-1", "protein_name": "Membrane spanning 4-domains A8", "gene_name": "Ms4a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNHPTAQGAVTLSENKSSTAEWEQEQERLIWQPGTVSMNTVTSQGPVANSVYVVAPHNSYPVVPGTMPQVPLYPSNQPQVHVIPGNLPGLVPAMTEPPAQRVLKKGQVLGAIQILIGLVHIGLGSIMITNLFSLYTPVSLYGGFPFWGGIWFIISGSLSVAAETQPNSPCLLNGSVGLNIFSAICSAVGIILFITDISISGGYVYPDYYPYHDYGVSTGVAISCVLLIFCLLELSIASVSSHFGCQVACCRYNNVDVVIPNVYATNTVVFPEPPNPIPSYSDAIRDSR", "length": 288 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZSU4-1", "protein_name": "Membrane spanning 4-domains A15", "gene_name": "Ms4a15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWKRRGRGESAARTAAVASRNASGLRPPPAILPTSMCQPPGIMQFEESPLGAQAPRATQPPDLRPMETFLTGEPKALGTVQILIGLIHLGFGSVLLMVRRGHLGMLFIEGGVPFWGGACFIISGSLSVAAERNHTSCLVRSSLGTNILSAMAAFAGTAILLMDFGVTNWDVGRGYLAVLTIFTILEFFIAVIATHFGCQATRAQTNASVIFLPNAFGTDFSIPSPAVSPPPAYDNVAYMPKESSE", "length": 245 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUX6-1", "protein_name": "Membrane spanning 4-domains A18", "gene_name": "Ms4a18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNQENVSAVTVTVPGNVRAIQPTYAVVSGGQEQPLQKATMHPASATVLQCNPGSANFQNPHVVIQNPAGMTGLQARPTGLQYPAGMASVQTAPGVIQYSPEMTSVQILPGDPQNPLNTVPGPTQTSSHPQWNMSFMSFPEFNPKKFINEEVRTLGAIQILIGLFHVFSAFNPHIYWNFSVLGASGYLIWGGLSFIISGSLSVLAEKDTNSCVVNSSIGMNVISSIFSLTGILVIIIDLCFPTPGISFLMVTSGILLPFALLEFILTCVVSHFGCQAVCWPHFENMTVFPTMFGGNTVNTTTGPVSTTSPNSATNIPVQPTLPSDVPPEQLYHDVADHAQK", "length": 341 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A4C7-1", "protein_name": "Membrane spanning 4-domains A3", "gene_name": "Ms4a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQEFHNTGLGTSPGRHMKPEETHDSVYRPLDEIHHVQRGVLQALGAIQILNGILILALGIFLVCLKQLSHHFINFFFFTFYTGYPLWGAVFFITSGSLSVAAGRSPTRTLMQNSFGMNIASTMIAFVGTAFLSVHLALNTLAFRACRSSQSPDICIFLGSSSNGLVSLMLIFTLLELALTISLSVMWCLGNVCGLREEISSSPPNSVESGIPPEESDSENLITQPQTIEE", "length": 232 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A4D6-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 4C, pseudogene 1", "gene_name": "Ms4a4c-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGLAQSTMAVVPGGAQPLEQSAIQSHMWDENKKTFLKGEPKVLGVVQIMIALINLSLGIIMMTNTVSEPLISVALLSPVWGPIMFIISGSLSIAAGVKTTKSLVISSLSLNTISSVVAAAASIMGIISVVLSTHGPFINNHPIARALDALMLVLNLLEFCIAVSVSAFGCKASCCNSSEVLVVLPSNPAVTGMAPSMPLQQLLLLEHQGKNVPENVYLGEIV", "length": 223 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A4Y3-1", "protein_name": "Membrane spanning 4-domains A1", "gene_name": "Ms4a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPRNSVSGPFPTEPTKGPLAMQPAQKVIPRRPSSLVGPTQSFFMRESKALGAVQIMNGLFHISLGGLLMIPTGVFAPICLSVWYPLWGGIMYIISGSLLAAAAEKTSRKSLVKAKVIMSSLSLFAAISGIILSIMDILNITVSHFLKMERLELIKTPKLYVDIYNCEPSNSSEKNSPSTQYCNSVQSVFLGILSVMLISAFFQKLVTAGVVENEWKRVCSRPKSNVVLLSAGEKKEQTIKMKEEIIELSGVSSQPKNEEEIEIIPVQEEEEEEAEINFPAPPQEQESLPVENEISP", "length": 298 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A8R9-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 4C", "gene_name": "Ms4a4c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGLAQSTTAVVPGGTQPSEPSVIKSQRWNENKEKFLKGEPKVLGVVQVMIALINLSLGVIVMKTMGFGSLISVALQAPIWGPVMFIVSGSLSIAAGVKTTKSLVISSLSLNTISSVLAAAASIMGVVSVVLSTYSFLYGSDPITRALDVLMLILNILEFCIAVSISAFGCKASCCNSSEVLVVLPSNPPVTVMAPSIPLQPLLPPECQGKNVPENVYPGEIV", "length": 223 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LVJ1-1", "protein_name": "Membrane spanning 4-domains A12", "gene_name": "Ms4a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDIRTSFQTTYPGMRGTIPNPYPPTSSMGLHPQQPLGFSNVGNQVRTGQVSFITSPGIFPNNQLGRENVPRVNPAPGAATSNVKDAAVALGGVQITIGLMHIGFGVVLGLLSTSYSMTWAFYSTAFIGGYPFWGGVFFIVSGSLSVSAFKKFSDCLVKSTLIINIFSIISAFVGVVLFLCDLNNNGHYYQDYWMVLSGRGIAGVLAIFSLLEFSIAWATAYFAYQTILHGNRSVLVAPTVYAANHLMQESSPASPIYDNVPDYAVRQ", "length": 268 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LZT4-1", "protein_name": "Membrane spanning 4-domains A6A", "gene_name": "Ms4a6a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPQVVINDTVTVTSPNGISFPQTDKPQPPHQRQDSLKKHLKAEIKVMAAIQIMCSVMVLALGIILASVPSVPHFTSVFSVLLKSGYPFMGALFFAISGILSVITEKKMTKPLVQCSLALSILSILSALIGLVILSVSLTALEPALQQCKLIATQQPVTTPHYYRFFHHELADKNCFTAKAALTGVFSLMLISSVLELGLAVLTTILWWKQSFSDFSGNVIFLSQDSKNKSSISSESLCNPAYEK", "length": 245 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M4I8-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 4C like 1", "gene_name": "Ms4a4cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGLAQTTMAVVPGGTQPLEPSVIKSQRWNENKETFLKGEPKVLGVVQVMIALINLSLGIIMMIPTFVERPFSVILLAPIWGPIMFIISGSLSIAAGVKTTKSLVISSLSLNAIISVVAAAVSIISIISVVVGAYSSRFYAHPIVNALDVLMLILNILEFCIAVSISAFGCNASCCNSSEVLVVVPSNPAVTVTAPPMTLQTLLP", "length": 205 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FJ62-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 6B", "gene_name": "Ms4a6b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPQVVTNETITVISPNRINFPQTEEPQSTHQRQDSLKKLLKAEIKVMAAIQIMCAVMVLALGIILASVPSVPLFTSVFSVLLKSGYPFVGPLFQFIVSGILSIITETKSTKTLVDGSLTLNILSVSFAFMGIIIMSASLAGLHPASEQCKLSKEGIRNEHDYYELSYDSDKKKCSTDKSILTGVFSLMLISTVLELGLAVLSALLWWKQSRSDSPGNVIFLSHNSNDESNVESKALCNSAYEEQMVC", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3V955-1", "protein_name": "Membrane spanning 4-domains A14", "gene_name": "Ms4a14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAPSEEKRRNHVIIIDPDETVLTAYPYRPHSSLLDFLKGEPKLLGAIQILLSLVIIGLGVIVTLNFMFSSKKVPLVILSGYPFWGAVIFFLTGFVTKSHDKQRQILKQDITVMNIFSSLTALAGIALILFSFTQHHKFCHIPSLDGPCVVGKTLLLGILSILLIITIVEFSISVTIVSLRSRCWTSPREAVFFFPSESPLNIEHPTPEENNTLQFEFQEKSSKDKTVSSIKSVFLGGYAFFKLRVSRNPSAPKTIPQKSDKGTSSMHVPPVEQEAIPPLSPEQEAKLNTLPLSLKPHSSENTPQKDSRTDHLIDEDLSSIIRQTSDMQSNVLDYENASVKGLKTPSSHNFFHFSPENLSSQSLVASLSTQVLQSKQPSLHISESYDLASEDFLSENIPSQDNQDQDIPSPYTPPQDMQFQVILAQDISSQETPHREPSYQDTLTKDASPQETPNQYILTKEIPSQETPFQGNPPQGTPSQGTLSQGTPPKGTPSQGTLPKGTSSQGTLSQGTPSQGTLPQGTPSEGTPIQGTPSEGTLIQGTPFQGTPSAVTLSQGTPPQGTPSAGTLSQGTLPQGTPSQGTLPQGTPSQGTLPQGTPSQGTLSQGTPSQGTPPQGTPPQGTPSEGTPFQGTPTQGTPSKELSFQHSLTKDTLSQETPYQETPFQDTLTQNTPSQDIQPEEILSQEISSQDTPFQITPSQNIKYEDILSQDKISQNTQTQNIVPQILNTGVQIQQHPEIFYKDIRTEVMEMTEEWQSNQDKKPTRRLSLSLPGKRGQFYPKRYSLDLQVKTEKPRRYSEDIQSRSTRRKSIDQQIKAWISPKKHTTEKQNAYTQTQEQAEDQQVKEEEVPVQQSQTEQIKHQKSVEELVSKDKENKDQQCDKEQPPQEQAQVQPAEDQHPKEEKTQLQNWQGGQQVLIKRSPMQLSDNWDSQSHQYTESSCSFWSTPSWQPISQRSQDWVSQGWRNKDWKAQEWQFAVQPSLDWESQELLERESLRQRALYRQIQPHTTIIQQTPDHQLRNFIFQVGLRQDTRQQDSESGVLIEDVSEDDAQSGDREPGDTEDTCQKPTDQRSEDLRPDNYPASFQSLVPYTYVTCLSNIASEQEVQNNTPYSGSSKDLNATSSSSYQRDQQQYEDSD", "length": 1139 }, "evidence": [ { "id": "FB:FBgn0036416", "url": "https://alliancegenome.org/gene/FB:FBgn0036416#orthology", "database": "AGR" }, { "id": "MGI:2686122", "url": "https://alliancegenome.org/gene/MGI:2686122#orthology", "database": "AGR" }, { "id": "HGNC:30706", "url": "https://alliancegenome.org/gene/HGNC:30706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" }, { "id": "RGD:727900", "url": "https://alliancegenome.org/gene/RGD:727900#orthology", "database": "AGR" }, { "id": "A0A087WSD2", "url": "https://omabrowser.org/oma/group/A0A087WSD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "J3QN01-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 18", "gene_name": "Ms4a18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNQENVSAVTVPSNVQVMQPTYAVVSGSHEQPLGKTTTYPASATMLQYNPGSANFQNPQVMIQNPAGTTGLQAGPTGLQYSAGMAGVQAPPGVIQYSPEVTSVQIPPGDPQNPLNTVPGPTQTSSLPQWNMSFMTFPEFNPKKFINEEVRTLGAIQILIGLFHIFSAVNPQLYNTQFFVVPLLGVSGYLIWGGLSFIISGSLSVLAEKNSNSCVVNSSIGMNVVSSIFSLTGIIIIIVQLSIYPSEISPLMSSMKAAAGSILPFALLEFILTCIASHFGCQAVCCAHFQNMTMFPTIFGGNTVNTTTGPGNTTIPNSTTSIPVQTTLPSNVPLEQVYQDVAQK", "length": 344 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3W2-1", "protein_name": "Membrane spanning 4-domains A4A", "gene_name": "Ms4a4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITIQGTGQTALEAGYGAQQNGQPLYVDSHSWKRMTEKFLKGEPKILGIVQIVIAIMNLSIGLMMIGATVSSGEILPISVYIGYPIWGSIMFIISGSFSIVAGRRTTKGLVRSSLGLNITSSVFAFAGMIINSLSPSIYSFHVYFCTYRSTSEGCRMTLSILMGLDIVVVILSVLEFCIGISLSAYGCRVMCCNPGGVVIIMPSKPPMPETAYPVSLQSGLGPPEHQQKNVPGKSH", "length": 236 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R8A0-1", "protein_name": "Membrane spanning 4-domains A5", "gene_name": "Ms4a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKNVHSPVFLVFPPEIITSEYRTAEFTATAYDSQNQVQKILIRKLKILGFINSGAFLIALKRKTTDTLIKMSQAMNLLSALGAAAGIILLIFAFLLDGEFICGYSPDGIQCGAITTLFVGILIMLMIFSVAELFISLFSSILGCYSEESGGCC", "length": 155 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11836-1", "protein_name": "B-lymphocyte antigen CD20", "gene_name": "MS4A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP", "length": 297 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13386-1", "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta", "gene_name": "Ms4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTENKSRADLALPNPQESPSAPDIELLEASPPAKALPEKPASPPPQQTWQSFLKKELEFLGVTQVLVGLICLCFGTVVCSTLQTSDFDDEVLLLYRAGYPFWGAVLFVLSGFLSIMSERKNTLYLVRGSLGANIVSSIAAGLGIAILILNLSNNSAYMNYCKDITEDDGCFVTSFITELVLMLLFLTILAFCSAVLLIIYRIGQEFERSKVPDDRLYEELHVYSPIYSALEDTREASAPVVS", "length": 243 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P19437-1", "protein_name": "B-lymphocyte antigen CD20", "gene_name": "Ms4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGPFPAEPTKGPLAMQPAPKVNLKRTSSLVGPTQSFFMRESKALGAVQIMNGLFHITLGGLLMIPTGVFAPICLSVWYPLWGGIMYIISGSLLAAAAEKTSRKSLVKAKVIMSSLSLFAAISGIILSIMDILNMTLSHFLKMRRLELIQTSKPYVDIYDCEPSNSSEKNSPSTQYCNSIQSVFLGILSAMLISAFFQKLVTAGIVENEWKRMCTRSKSNVVLLSAGEKNEQTIKMKEEIIELSGVSSQPKNEEEIEIIPVQEEEEEEAEINFPAPPQEQESLPVENEIAP", "length": 291 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20490-1", "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta", "gene_name": "Ms4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTENRSRADLALPNPQESSSAPDIELLEASPAKAAPPKQTWRTFLKKELEFLGATQILVGLICLCFGTIVCSVLYVSDFDEEVLLLYKLGYPFWGAVLFVLSGFLSIISERKNTLYLVRGSLGANIVSSIAAGTGIAMLILNLTNNFAYMNNCKNVTEDDGCFVASFTTELVLMMLFLTILAFCSAVLFTIYRIGQELESKKVPDDRLYEELNVYSPIYSELEDKGETSSPVDS", "length": 235 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01362-1", "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta", "gene_name": "MS4A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTEIVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSPPIDL", "length": 244 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2TVW9-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 5", "gene_name": "Ms4a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSKNVHSPLFLVFPPEVTTQEYQTTELTATAYNPQNRVQKIIIRKLEILGFINSGAFLIALKRKTTDTLIKMSRAMNLLSALGAAAGIILLIFGFLLDGEFICGYSPDGMQCGVITILFIGILVMLMIFSIVELFISLFSSVLGCYTEGRGCC", "length": 154 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3C1V0-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 18", "gene_name": "MS4A18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEQVIGANSVPGIIAPDNVHVIQPSNPVASGNHLQPSEVTTYPISPKVIHCDTGRANLQNLLVVNQNSAAGVQSQPIGYQRQYPVGTASLQTVPGVIQYTQGTTNLQTWPGDLQNPLNANPGLTHTSNSSQWNTSFASFTSFNPKKFINEEVRTLGAIQILIGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVTTYSKAVSGGLLPFALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFSFNPANTTTSPVNATTGPVNAATGPVSATNGPVNTTIHPVNTTTSPVNTTTSPVNVTTGPVNANIGPVNVTTGPVNTTTAPAKATTSCVNAIHTSNVPPNPRTKK", "length": 398 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UPL6-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 15", "gene_name": "Ms4a15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWERRGRGESAAGTAAVASRNASGLRPPPAILPTSMCQPPGIMQFEESQLGAQAPRATQPPDLRPMETFLTGEPKALGTVQILIGLIHLGFGSVLLMVRRGHLGMLFIEGGVPFWGGACFIISGSLSVAAERNHTSCLLKSSLGTNILSAMAAFAGTAILLMDFGVTNWDVGRGYLAVLTIFTILEFFIAVIATHFGCQATRAQTNASVIFLPNAFGTDFNIPSPAVSPPPAYDNVAYMPKESSE", "length": 245 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q567H8-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 17A.11", "gene_name": "ms4a17a.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTVGAMNPSTIVIQLQPPTQTAPTVTGTSSSVPVYIQHVAGVSPLQGIQAFLKGQPKALGTVQIIIGLLTFMLGIVSTVYVDSSFVFSGVSYWGSLIYIIAGSLSIAADSKINLPAGLCLVRASLGMNIFSAIAAGIAIIMLSVDLALGPFSPRYCGDSYYCYNYKTLFLGIRGVLLVFAILEFFISLSLSAFGCKVTCCYYPQISVVNNPLIQHPPAENPQQYIQYPQEVPEPCFQHPPAEAPPAYTEGK", "length": 252 }, "evidence": [ { "id": "MGI:2686122", "url": "https://alliancegenome.org/gene/MGI:2686122#orthology", "database": "AGR" }, { "id": "HGNC:30706", "url": "https://alliancegenome.org/gene/HGNC:30706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" }, { "id": "RGD:727900", "url": "https://alliancegenome.org/gene/RGD:727900#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N5U1-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 15", "gene_name": "MS4A15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV", "length": 240 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920C4-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 3", "gene_name": "Ms4a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPEETGGSVYQPLDESRHVQRGVLQALGAIQILNGILILALGIFLVCLQHVSHHFRHFFFFTFYTGYPLWGAVFFISSGSLTVAAGRNPTRMLMQNSFGINIASTTIAFVGTVFLSVHLAFNTQAFKGCQSSPSPDVCISLGSSSDGLVSLMLILTLLELSVTISISAMWCLGNVCGLREAITSPPNSVESGILPEGSDSENLNTQPQASEE", "length": 213 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HJ5-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 3", "gene_name": "MS4A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASHEVDNAELGSASAHGTPGSEAGPEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPNSV", "length": 214 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96JA4-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 14", "gene_name": "MS4A14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLVAITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQLQFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQPRTVNLLAKNPLTG", "length": 679 }, "evidence": [ { "id": "MGI:2686122", "url": "https://alliancegenome.org/gene/MGI:2686122#orthology", "database": "AGR" }, { "id": "HGNC:30706", "url": "https://alliancegenome.org/gene/HGNC:30706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" }, { "id": "RGD:727900", "url": "https://alliancegenome.org/gene/RGD:727900#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96JQ5-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 4A", "gene_name": "MS4A4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV", "length": 239 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N05-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 4D", "gene_name": "Ms4a4d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGLAQTTMAVVPGGAPPSENSVIKSQMWNKNKEKFLKGEPKVLGAIQVMIAFINFSLGIIIILNRVSERFMSVLLLAPFWGSIMFIFSGSLSIAAGVKPTKAMIISSLSVNTISSVLAVAASIIGVISVISGVFRQFRSQPAIASLDVLMTILNMLEFCIAVSVSAFGCKASCCNSSEVLVVLPSNSAVTVTAPPMILQPLPPSECQGKNVPENLYRNQPGEIV", "length": 225 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99N07-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 6D", "gene_name": "Ms4a6d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPQVVTSETVTVISPNGISFPQTDKPQPSHQSQDSLKKHLKAEIKVMAAIQIMCAVMVLSLGIILASVPSNLHFTSVFSILLESGYPFVGALFFAISGILSIVTEKKMTKPLVHSSLALSILSVLSALTGIAILSVSLAALEPALQQCKLAFTQLDTTQDAYHFFSPEPLNSCFVAKAALTGVFSLMLISSVLELGLAVLTATLWWKQSSSAFSGNVIFLSQNSKNKSSVSSESLCNPTYENILTS", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99N08-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 6C", "gene_name": "Ms4a6c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPQVVTNETITTISPNGINFPQKDESQPTQQRQDSLKKHLKAEIKVIVAIQIMCAVTVLALGIILASVPPVPYFNSVFSVLLKSGYPFIGALFFIASGILSIITERKSTKPLVDASLTLNILSVSFAFVGIIIISVSLAGLHPASEQCKQSKELSLIEHDYYQPFYNSDRSECAVTKSILTGALSVMLIISVLELGLALLSAMLWLREGVLTSLRM", "length": 217 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99N09-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 6B", "gene_name": "Ms4a6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPQVVTSETVAMISPNGMSLPQTDKPQPFHQWQDSLKKHLKAEIKVMAAIQIMCAVMVLSLGIILASVPSNLHFTSVFSVLLKSGYPFIGALFFIVSGILSIVTETKSTKILVDSSLTLNILSVSFAFMGIIIISVSLAGLHPASEQCLQSKELRPTEYHYYQFLDRNECFAAKSVLAGVFSLMLISTMLELGLAVLTAMLWWKQSHSNIPGNVMFLPHSSNNDSNMESKVLCNPSYEEQLVC", "length": 244 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99N10-3", "protein_name": "Membrane-spanning 4-domains subfamily A member 8", "gene_name": "Ms4a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRPTAQGAVNLSGSKFSTAKSWEPEQERLTWQPGTVSMNTVTSPGPMANSVYVVAPPNSYPVVPGTVPQMPIYPSNQPQVHVISGHLPGLVPAMTEPPAQRVLKKGQVLGAIQILIGLVHIGLGSIMITNLFSHYTPVSLYGGFPFWGGIWFIISGSLSVAAETQPNSPCLLNGSVGLNIFSAICSAVGIMLFITDISISSGYIYPSYYPYQENLGVRTGVAISSVLLIFCLLELSIASVSSHFGCQVACCHYNNPGVVIPNVYAANPVVIPEPPNPIPSYSEVVQDSR", "length": 290 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY19-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 8", "gene_name": "MS4A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPPSYSSEIQANK", "length": 250 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D3F6-1", "protein_name": "MS4A4C protein", "gene_name": "Ms4a4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGQEQTTMAVVPGGAPPSENSVMKSQMWNENKEKFLKGEPKVLGVVQVMIALINLSFGIIILANLSSEPLISVVLMAPIWGPIMFIVSGSLSIAAGVKPTKSLIISSLTLNTITSVLAATASIMGVVSVAVGSQFPFRYNYTITKGLDILMLILNMLEFCIAVSISAFGCKASCCNSSEVLVVLPSNPAVTVMAPPVTLQPLPPSEHQGKNVPENVYKNHSEEIV", "length": 226 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ES61-1", "protein_name": "Membrane-spanning 4-domains, subfamily A, member 4B", "gene_name": "Ms4a4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGQEQTTMAVVPGVAVPSKNSVMTSQMWNEKKEKFLKGEPKVLGVLQVMIAIINLSLGIIILTTLFSELPTSVMLMVPIWGSIMFIVSGSLSIAAGVTPTKCLIVASLTLNTITSVLAATASIMGVVSVAVGSQFPFRYNYTITKGLDVLMLIFNMLEFCLAVSVSAFGCEASCCNSREVLVVLPSNPVETVMAPPMTLQPLLPSEHQGTNVPGNVYKNHPGEIV", "length": 226 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZW8-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 7", "gene_name": "MS4A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI", "length": 240 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H2W1-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 6A", "gene_name": "MS4A6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDCGYEELLTS", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H3V2-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 5", "gene_name": "MS4A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSILGCHSEDCDCEQCC", "length": 200 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NXJ0-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 12", "gene_name": "MS4A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSSKPTSHAEVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIFASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPNMYESNPVTPASSSAPPRCNNYSANAPK", "length": 267 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-157", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-157#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUD8-1", "protein_name": "LP03067p", "gene_name": "Dmel\\CG7924", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKPQYHLAAVLLCFVFTTAQVVPNAEIGRITIQVPLLSNGKPVILTNQEREEIATVQEIKPGKVHVVQEVVVPPTVKSDNKVRVTRSVSDSGIPNHGIPNPGIPNHGIPNRGIPNDGIPNPGIPNHGIPNPGIPNHGIPNRGIPNDGIPNPGIPNHGIPNPGIPNHGIPNRGIPNDGIPNPGIPNHGIPNPGIPNPDASELKPVVVMPSSRTTSAPASTSMPKRVPTRNCFHLLMGGTTTTSPVDMMTPPSMENCDELCTKFEYSPICAHNGICIHEFANQCVMNTFNCKHRDLSFRAVDEDVCRLGVCMRRCKEEELAL", "length": 321 }, "evidence": [ { "id": "FB:FBgn0036416", "url": "https://alliancegenome.org/gene/FB:FBgn0036416#orthology", "database": "AGR" }, { "id": "MGI:2686122", "url": "https://alliancegenome.org/gene/MGI:2686122#orthology", "database": "AGR" }, { "id": "RGD:727900", "url": "https://alliancegenome.org/gene/RGD:727900#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A087WSD2", "url": "https://www.uniprot.org/uniprotkb/A0A087WSD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1202, "end_pos": 1204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1214, "end_pos": 1216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A087WSD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1232, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A087WSD2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A087WSD2" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 528, 533, 538, 553, 558, 563, 568, 583, 588, 598, 608, 618, 638, 643, 648, 658, 663, 678, 683, 688, 1040 ], "snv_sites": [ 249 ], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1202, "end_pos": 1204 }, { "start_pos": 1214, "end_pos": 1216 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 893, "end_pos": 895 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 21 }, { "field": "total_sites", "count": 21 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 21 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 21 }, { "field": "exact_o_linked_sites", "count": 21 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 21 }, { "field": "total_sites", "count": 21 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 21 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 21 }, { "field": "exact_o_linked_sites", "count": 21 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }