{ "uniprot_canonical_ac": "A0A087WS64-1", "uniprot_ac": "A0A087WS64", "uniprot_id": "A0A087WS64_MOUSE", "mass": { "chemical_mass": 41618.0, "monoisotopic_mass": 41618.0 }, "refseq": {}, "gene_names": [ { "name": "Zfp658", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64", "id": "A0A087WS64" }, { "name": "Gm7145", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64", "id": "A0A087WS64" } ], "protein_names": [ { "name": "Zinc finger protein 658", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64/entry#names_and_taxonomy", "id": "A0A087WS64" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A087WS64", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Zfp658", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64", "locus": { "chromosome": "1", "start_pos": 117914614, "end_pos": 117893669, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000100617", "url": "https://www.ensembl.org/id/ENSMUSG00000100617" } ] } } ], "crossref": [ { "id": "MGI:3648947", "url": "https://alliancegenome.org/gene/MGI:3648947", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A087WS64", "url": "https://alphafold.ebi.ac.uk/entry/A0A087WS64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSMUSG00000100617", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000100617", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "3648947", "url": "http://www.informatics.jax.org/marker/MGI:3648947", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "HENIHTW", "url": "https://omabrowser.org/oma/group/HENIHTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-212436", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "A0A087WS64", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WS64-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASCQVLLTFMDVALEFSKEEWECLDSAQRALYRDVMLENYNNLVSVGVAVSKSEVITFLEENKDPWIVDRNGTERRTPDQEAPDTLPERTQSPNPKTHYRISTRVTFYKCIECGKSFTKLSRLKVHQRLHTGDKPYKCNECGKSFKHLSSVKIHHRLHTGYKPYKCNECGKSFTKSSHLKVHQRLHTGDKPYKCNECGKSFTRYSDLKVHQRIHTGYKPYKCNDCGKSFTKSSHLKVHHRLHTGDKPYKCNECGKSFTQFSDLKVHQRIHTGDKPCKCNDCGKSFTKFSSLKVHQRLHTGDKPYKCNKCGKSFKHLSSAKIHHRLHTGDKPYKCNECGKSFTQVSYLKVHQRIHTGDKP", "length": 360, "header": "tr|A0A087WS64-1|A0A087WS64_MOUSE Isoform 1 of Zinc finger protein 658 OS=Mus musculus OX=10090 GN=Zfp658 PE=4 SV=1 CANONICAL=A0A087WS64-1" }, "isoforms": [ { "isoform_ac": "A0A087WS64-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64/entry#A0A087WS64-1", "sequence": { "sequence": "MASCQVLLTFMDVALEFSKEEWECLDSAQRALYRDVMLENYNNLVSVGVAVSKSEVITFLEENKDPWIVDRNGTERRTPDQEAPDTLPERTQSPNPKTHYRISTRVTFYKCIECGKSFTKLSRLKVHQRLHTGDKPYKCNECGKSFKHLSSVKIHHRLHTGYKPYKCNECGKSFTKSSHLKVHQRLHTGDKPYKCNECGKSFTRYSDLKVHQRIHTGYKPYKCNDCGKSFTKSSHLKVHHRLHTGDKPYKCNECGKSFTQFSDLKVHQRIHTGDKPCKCNDCGKSFTKFSSLKVHQRLHTGDKPYKCNKCGKSFKHLSSAKIHHRLHTGDKPYKCNECGKSFTQVSYLKVHQRIHTGDKP", "length": 360, "header": "tr|A0A087WS64-1|A0A087WS64_MOUSE Isoform 1 of Zinc finger protein 658 OS=Mus musculus OX=10090 GN=Zfp658 PE=4 SV=1 CANONICAL=A0A087WS64-1" }, "locus": { "chromosome": "1", "start_pos": 117914199, "end_pos": 117893968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000185381.2", "url": "https://www.ensembl.org/id/ENSMUST00000185381.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140916.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140916.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Modernizing reference genome assemblies.", "journal": "PLoS Biol.", "date": "2011", "authors": "Church Deanna M, Schneider Valerie A, Graves Tina, Auger Katherine, Cunningham Fiona, Bouk Nathan, Chen Hsiu-Chuan, Agarwala Richa, McLaren William M, Ritchie Graham R S, Albracht Derek, Kremitzki Milinn, Rock Susan, Kotkiewicz Holland, Kremitzki Colin, Wollam Aye, Trani Lee, Fulton Lucinda, Fulton Robert, Matthews Lucy, Whitehead Siobhan, Chow Will, Torrance James, Dunn Matthew, Harden Glenn, Threadgold Glen, Wood Jonathan, Collins Joanna, Heath Paul, Griffiths Guy, Pelan Sarah, Grafham Darren, Eichler Evan E, Weinstock George, Mardis Elaine R, Wilson Richard K, Howe Kerstin, Flicek Paul, Hubbard Tim", "evidence": [ { "database": "UniProtKB", "id": "A0A087WS64", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64" } ], "reference": [ { "type": "PubMed", "id": "21750661", "url": "https://glygen.org/publication/PubMed/21750661" } ] } ], "pathway": [ { "id": "R-MMU-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1Y7VMN9-1", "protein_name": "KRAB box domain containing 5", "gene_name": "Krbox5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSFRDVAIDFSAEEWECLEPAQWHLYRDVMLENYSHLVFLELADSKPQLVTFLEQRQQSTGVKRQEVLQTPCRELWGRNPQCHYSQNWNA", "length": 91 }, "evidence": [ { "id": "HGNC:26987", "url": "https://alliancegenome.org/gene/HGNC:26987#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I5ZMF7-1", "protein_name": "Zinc finger protein 780B", "gene_name": "Zfp780b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSSSQHTVCGLVTFRDVAVDFSQEEWACLDATQKVLYRDTMLETYSHLVTVVGSCLSKPHLITLLEQEKEPWMAVKEETDRPSPELETGYDAENISPENPINNGKFLKQSIKQLSRTFDFKDSSSSNGPNYSTFHGLKDCQGDADQQITNKEEMPPYTCQTLAHNIERAYECKECGKCLGCRSTLTQHQTIHTGEKPYECKECGKAFRLPQQLTRHQKFHSGEKPFKCNECGKAFHLPDLLKYHKTIHTGTKPFECRECGKAFNRVSNLVAHRIIHADVKPYECNECGKAFKRRSNLVQHQKIHSDERPFQCKDCGKGFIVLAQLTRHQNIHTGEKLFECHECGKAFRLPQQLTRHQKSHSGEKPFKCNECGKAFHLPDLLKYHKTIHTGTKPFECRECGKSFNRVSNLVEHRIIHADVKPYACNQCGKAFKRQKSLMQHQKIHLGERPFQCKDCGKAFIVLSHLTRHQTIHTGEKSFECNECGKKFRTATHLVMHQSIHTGEKPFECNVCGKAFRLQVYLSEHQKTHMEEKHFECNVCGKVFRLQVYLSEHQKTHTEEKPFKCKLCGSAFRSKYQLSKHHTIHTDEKPYQCKECGKCFRQRSNFTDHQSIHTGKKPFQCKECGKFYRLNTLLIRHQKSHSGERPYECKECGKAFHLPSELNNHQIVHTSKRPFECKVCGKSFKRESTLIQHGAVHAGVKSYECSECGKAFIHRSSLLHHRKIHSDEKPFKCQECGKAFVVLAYLTRHQSIHNGEKSFECHQCGSTFKYKSQLNKHQRSHTDVKLFQCMEGGNDFVPGIDLRINQGVCTGESPFQCNEYGEHFQHHNQFSWTY", "length": 835 }, "evidence": [ { "id": "HGNC:26987", "url": "https://alliancegenome.org/gene/HGNC:26987#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z2F6-1", "protein_name": "KRAB domain-containing protein 5", "gene_name": "KRBOX5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLTFRDVAIEFSREEWEHLDSDQKLLYGDVMLENYGNLVSLGLAVSKPDLITFLEQRKEPWNVKSAETVAIQPDIFSHDTQGLLRKKLIEASFQKVILDGYGSCGPQNLNLRKEWESEGKIILW", "length": 126 }, "evidence": [ { "id": "MGI:3648947", "url": "https://alliancegenome.org/gene/MGI:3648947#orthology", "database": "AGR" }, { "id": "HGNC:26987", "url": "https://alliancegenome.org/gene/HGNC:26987#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N782-1", "protein_name": "Zinc finger protein 525", "gene_name": "ZNF525", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALPQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLGISSKCTMKEFSSTAQGNTEVIHTGTLQRHERHHIGDFSFQEIEKDIHNFEFQWQEDERNGHEAPMTKIKKLMGSTEQYDHRHAGNKPIKYQLGSSFHSHLSELHIFQPKGKINNQVEKSINDASSVSTAQRISCRPKTHISNNYGDNFLNYSLLTQRQEVRMREKSFQCIESGKAFNYSSLLRKHQIIHLGEKQYKCDVCDKVFIRKRYLARHRRCHTGEKPYKCNECGKSFSQMSSLTYHHRLHTGEKPYKCEECDKAFRHNSALQRHRRIHTGEKPHKCNECGKTFSQKSYLACHRSIHTGKKPYECEECDKAFSFKSNLESHRITHTGEKPYKCNDCGKTFSHMSTLTCHRRLHTGEKPYKCEECDEAFRFKSSLERHRRIHNGEKLYKCNECGKTFSQELSLTCHCRLHSGEKPCKCGECDKAYSFK", "length": 479 }, "evidence": [ { "id": "MGI:3648947", "url": "https://alliancegenome.org/gene/MGI:3648947#orthology", "database": "AGR" }, { "id": "HGNC:29423", "url": "https://alliancegenome.org/gene/HGNC:29423#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NCK3-1", "protein_name": "Zinc finger protein 485", "gene_name": "ZNF485", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRAQIQGPLTFGDVAVAFTRIEWRHLDAAQRALYRDVMLENYGNLVSVGLLSSKPKLITQLEQGAEPWTEVREAPSGTHAVEDYWFETKMSALKQSTSEASVLGERTKSVMMEKGLDWEGRSSTEKNYKCKECGKVFKYNSSFISHQRNHTSEKPHKCKECGIAFMNSSSLLNHHKVHAGKQPYRCIECGKFLKKHSTFINHQRIHSREKPHKCIECGKTFRKNSILLSHQRIHTGQKPYKCNDCGKAFAQNAALTRHERIHSGEKPFKCNKCGRAFRDNSTVLEHQKIHTGEKPYQCNECGKAFRKSSTLISHQRMHTGEKPYHCSKCGKSFRYSSSFAGHQKTHSGNKPYQCRDCGKAFTKSSTLTGHQRIHTGEKPYHCKKCGKAFRHSSGLVEHQRLHTGEKPYKCNECGKAFPRSSALKQHKKIHNKERAMKCS", "length": 441 }, "evidence": [ { "id": "MGI:3648947", "url": "https://alliancegenome.org/gene/MGI:3648947#orthology", "database": "AGR" }, { "id": "HGNC:23440", "url": "https://alliancegenome.org/gene/HGNC:23440#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A087WS64", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A087WS64", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A087WS64", "url": "https://www.uniprot.org/uniprotkb/A0A087WS64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A087WS64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 360, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A087WS64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A087WS64" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 72, "end_pos": 74 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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