{
    "bcoid": "GLY_000690",
    "title": "Fruitfly Pathways (Reactome)",
    "description": "The Fruitfly Pathways (Reactome) dataset contains Drosophila melanogaster [taxid:7227] pathway information ...",
    "filename_list": "fruitfly_protein_pathways_reactome.csv",
    "filename": "fruitfly_protein_pathways_reactome.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Drosophila melanogaster"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
            "Reactome Pathway"
        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ]
    },
    "minitable": {
        "content": [
            [
                "R-DME-982459...",
                "Regulation o..."
            ],
            [
                "R-DME-985350...",
                "OGDH complex..."
            ]
        ],
        "headers": [
            "pathway_id...",
            "pathway_name..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "pathway_id"
                },
                {
                    "type": "string",
                    "label": "pathway_name"
                },
                {
                    "type": "string",
                    "label": "pathway_summary"
                },
                {
                    "type": "string",
                    "label": "reaction_id_list"
                }
            ],
            [
                "R-DME-9824594",
                "Regulation of MITF-M-dependent genes involved in apoptosis",
                "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
                "R-DME-9825754"
            ],
            [
                "R-DME-9853506",
                "OGDH complex synthesizes succinyl-CoA from 2-OG",
                "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
                "R-DME-71401,R-DME-9853499,R-DME-9853512"
            ]
        ]
    },
    "readme": "Name\n   - Fruitfly Pathways (Reactome)\n\nVersion\n   - v-2.10.1\n\nCreated on\n  - 2022-09-06T12:11:33.921445\n\nModified on\n   - 2024-05-21T15:41:33.867Z\n\nCreated by\n   -  [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Luke Johnson [luke.johnson@email.gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Cyrus Au-Yeung [cyruschauyeung@gwu.edu], Kate Warner [k.warner1@gwu.edu]\n\nAuthors\n   - \n\nChecksum\n   - \n\nUsability Domain\n   - The Fruitfly Pathways (Reactome) dataset contains Drosophila melanogaster [taxid:7227] pathway information from Reactome database and mapped to the UniProtKB canonical accessions. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB, Reactome and GlyGen.\n   - Reactome is an open-source, open access, manually curated and peer-reviewed pathway database. \n\nDescription Domain\n   Keywords\n   - pathways\n   - reactions\n   - REACTOME\n\n   Pipeline Steps\n   - Step-1: The script loads the Reactome Pathways for UniProtKB canonical accessions  from the triplestore containing triples from nt file and extracts the data as a csv dataset\n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: uniprot-proteome-drosophila-melanogaster.nt\n      URI: https:/data.glygen.org/ln2downloads/ebi/2025_10_01/uniprot-proteome-drosophila-melanogaster.nt\n   Output Subdomain\n      Name: fruitfly_protein_pathways_reactome.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.10.1/reviewed/fruitfly_protein_pathways_reactome.csv\n      Name: fruitfly_protein_pathways_reactome.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.10.1/reviewed/fruitfly_protein_pathways_reactome.stat.csv\n\nFields\n      Name: \"pathway_id\"\n     Description: \"Pathway Identifier\"\n      Unique Values: \"1173\"\n      Name: \"pathway_name\"\n     Description: \"\"\n      Unique Values: \"1172\"\n      Name: \"pathway_summary\"\n     Description: \"\"\n      Unique Values: \"7\"\n      Name: \"reaction_id_list\"\n     Description: \"\"\n      Unique Values: \"1164\"",
    "downloadurl": "/ln2data/releases/data/v-2.10.1/reviewed/fruitfly_protein_pathways_reactome.csv"
}
