{
    "uniprot_canonical_ac": "A0A8I5ZPY8-1",
    "uniprot_ac": "A0A8I5ZPY8",
    "uniprot_id": "A0A8I5ZPY8_RAT",
    "mass": {
        "chemical_mass": 18508.0,
        "monoisotopic_mass": 18508.0
    },
    "refseq": {
        "ac": "NP_001032415",
        "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032415"
    },
    "gene_names": [
        {
            "name": "Ndufb4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8",
            "id": "A0A8I5ZPY8"
        },
        {
            "name": "Ndufb4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032415",
            "id": "NP_001032415"
        }
    ],
    "protein_names": [
        {
            "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8#names_and_taxonomy",
            "id": "A0A8I5ZPY8"
        },
        {
            "name": "Complex I-B15",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8#names_and_taxonomy",
            "id": "A0A8I5ZPY8"
        },
        {
            "name": "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032415",
            "id": "NP_001032415"
        },
        {
            "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032415",
            "id": "NP_001032415"
        },
        {
            "name": "NADH-ubiquinone oxidoreductase B15 subunit",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8#names_and_taxonomy",
            "id": "A0A8I5ZPY8"
        }
    ],
    "function": [
        {
            "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5ZPY8",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00003195",
                    "url": "https://www.uniprot.org/uniprot/ARBA00003195#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "F1LPG5",
                    "url": "https://www.uniprot.org/uniprot/F1LPG5#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5ZPY8",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Ndufb4",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8",
            "locus": {
                "chromosome": "11",
                "start_pos": 65960277,
                "end_pos": 65966898,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000002721",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000002721"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000002721",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000002721",
            "database": "Bgee"
        },
        {
            "id": "288088",
            "url": "https://www.ncbi.nlm.nih.gov/gene/288088",
            "database": "GeneID"
        },
        {
            "id": "IPR009866",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009866",
            "database": "InterPro"
        },
        {
            "id": "rno:288088",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:288088",
            "database": "KEGG Pathway"
        },
        {
            "id": "PLFFWFY",
            "url": "https://omabrowser.org/oma/group/PLFFWFY/",
            "database": "OMA"
        },
        {
            "id": "1434967at2759",
            "url": "http://www.orthodb.org/?query=1434967at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR15469",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15469",
            "database": "PANTHER"
        },
        {
            "id": "PF07225",
            "url": "http://pfam.xfam.org/family/PF07225",
            "database": "Pfam"
        },
        {
            "id": "R-RNO-611105",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-611105",
            "database": "Reactome"
        },
        {
            "id": "R-RNO-6799198",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6799198",
            "database": "Reactome"
        },
        {
            "id": "NP_001032415",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032415",
            "database": "RefSeq"
        },
        {
            "id": "1307072",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307072",
            "database": "RGD"
        },
        {
            "id": "A0A8I5ZPY8",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5ZPY8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8-1",
            "database": "UniProtKB"
        },
        {
            "id": "F1LPG5",
            "url": "https://www.uniprot.org/uniprot/F1LPG5",
            "database": "UniProtKB"
        },
        {
            "id": "F1LPG5-1",
            "url": "https://www.uniprot.org/uniprot/F1LPG5-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MSFSKYKPAPLAALPNTLDPAEYDVSPETRKAQVERMSIRARLKREYLLQYNDPKRQTHIEDPALIRWTYARSANVYPNFRPTPKNSLLGAVAGLGPLIFWYYVIKTDRVSNRARCLAGLRGPSWVPPAVPCGDLSLCLPENSPFPLCLVSIPFWKELEFSLI",
        "length": 163,
        "header": "tr|A0A8I5ZPY8-1|A0A8I5ZPY8_RAT Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4  OS=Rattus norvegicus OX=10116 GN=Ndufb4 PE=1 SV=1 CANONICAL=A0A8I5ZPY8-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZPY8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8#A0A8I5ZPY8-1",
            "sequence": {
                "sequence": "MSFSKYKPAPLAALPNTLDPAEYDVSPETRKAQVERMSIRARLKREYLLQYNDPKRQTHIEDPALIRWTYARSANVYPNFRPTPKNSLLGAVAGLGPLIFWYYVIKTDRVSNRARCLAGLRGPSWVPPAVPCGDLSLCLPENSPFPLCLVSIPFWKELEFSLI",
                "length": 163,
                "header": "tr|A0A8I5ZPY8-1|A0A8I5ZPY8_RAT Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4  OS=Rattus norvegicus OX=10116 GN=Ndufb4 PE=1 SV=1 CANONICAL=A0A8I5ZPY8-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 63068995,
                "end_pos": 63063813,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000105325.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000105325.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000080099.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000080099.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F1LPG5-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8#F1LPG5-1",
            "sequence": {
                "sequence": "MSFSKYKPAPLAALPNTLDPAEYDVSPETRKAQVERMSIRARLKREYLLQYNDPKRQTHIEDPALIRWTYARSANVYPNFRPTPKNSLLGAVAGLGPLIFWYYVIKTDRDKKERLIQEGKLDRKFSISY",
                "length": 129,
                "header": "tr|F1LPG5-1|A0A8I5ZPY8_RAT Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4  OS=Rattus norvegicus OX=10116 GN=Ndufb4 PE=1 SV=1 CANONICAL=A0A8I5ZPY8-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 63070369,
                "end_pos": 63063813,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000003674.8",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000003674.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000003674.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000003674.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:288088",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:288088",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-611105",
            "name": "Respiratory electron transport",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-611105",
            "resource": "Reactome",
            "description": "Respiratory electron transport"
        },
        {
            "id": "R-RNO-6799198",
            "name": "Complex I biogenesis",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6799198",
            "resource": "Reactome",
            "description": "Complex I biogenesis"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O95168-1",
            "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4",
            "gene_name": "NDUFB4",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSFPKYKPSSLRTLPETLDPAEYNISPETRRAQAERLAIRAQLKREYLLQYNDPNRRGLIENPALLRWAYARTINVYPNFRPTPKNSLMGALCGFGPLIFIYYIIKTERDRKEKLIQEGKLDRTFHLSY",
                "length": 129
            },
            "evidence": [
                {
                    "id": "41498732",
                    "url": "http://www.informatics.jax.org/homology/41498732",
                    "database": "MGI"
                },
                {
                    "id": "41498731",
                    "url": "http://www.informatics.jax.org/homology/41498731",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9CQC7-1",
            "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4",
            "gene_name": "Ndufb4",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSGSKYKPAPLATLPSTLDPAEYDVSPETRRAQVERLSIRARLKREYLLQYNDPKRVSHIEDPALIRWTYARSANIYPNFRPTPKNSLLGAVAGFGPLIFWYYVFKTDRDRKERLIQEGKLDRKFNISY",
                "length": 129
            },
            "evidence": [
                {
                    "id": "41498732",
                    "url": "http://www.informatics.jax.org/homology/41498732",
                    "database": "MGI"
                },
                {
                    "id": "41498731",
                    "url": "http://www.informatics.jax.org/homology/41498731",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "mitochondrial inner membrane",
                        "id": "GO:0005743",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPY8",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial respiratory chain complex I",
                        "id": "GO:0005747",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005747",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPY8",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "response to oxidative stress",
                        "id": "GO:0006979",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPY8",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial respiratory chain complex I assembly",
                        "id": "GO:0032981",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPY8",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPY8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}