{
    "uniprot_canonical_ac": "A0A8I5ZPV1-1",
    "uniprot_ac": "A0A8I5ZPV1",
    "uniprot_id": "A0A8I5ZPV1_RAT",
    "mass": {
        "chemical_mass": 59997.0,
        "monoisotopic_mass": 59997.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Tbc1d22a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1",
            "id": "A0A8I5ZPV1"
        }
    ],
    "protein_names": [
        {
            "name": "TBC1 domain family, member 22a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1#names_and_taxonomy",
            "id": "A0A8I5ZPV1"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5ZPV1",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Tbc1d22a",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1",
            "locus": {
                "chromosome": "7",
                "start_pos": 127081978,
                "end_pos": 127223231,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000017057",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000017057"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000017057",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017057",
            "database": "Bgee"
        },
        {
            "id": "IPR000195",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195",
            "database": "InterPro"
        },
        {
            "id": "IPR035969",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969",
            "database": "InterPro"
        },
        {
            "id": "PNMEMET",
            "url": "https://omabrowser.org/oma/group/PNMEMET/",
            "database": "OMA"
        },
        {
            "id": "PF00566",
            "url": "http://pfam.xfam.org/family/PF00566",
            "database": "Pfam"
        },
        {
            "id": "XP_017458968",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017458968",
            "database": "RefSeq"
        },
        {
            "id": "1306588",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306588",
            "database": "RGD"
        },
        {
            "id": "A0A8I5ZPV1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5ZPV1-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5ZSU1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZSU1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5ZSU1-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZSU1-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I6AH78",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AH78",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I6AH78-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AH78-1",
            "database": "UniProtKB"
        },
        {
            "id": "D3Z994",
            "url": "https://www.uniprot.org/uniprot/D3Z994",
            "database": "UniProtKB"
        },
        {
            "id": "D3Z994-1",
            "url": "https://www.uniprot.org/uniprot/D3Z994-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MASDGARKQFWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMATESLNSEVVMETAHRVLRNHSQRQNQPSQKKPEPEPQPIAEPPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDQEDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADAPNHYKKSSTPLPRH",
        "length": 522,
        "header": "tr|A0A8I5ZPV1-1|A0A8I5ZPV1_RAT Isoform 1 of TBC1 domain family, member 22a  OS=Rattus norvegicus OX=10116 GN=Tbc1d22a PE=1 SV=1 CANONICAL=A0A8I5ZPV1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZPV1-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1#A0A8I5ZPV1-1",
            "sequence": {
                "sequence": "MASDGARKQFWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMATESLNSEVVMETAHRVLRNHSQRQNQPSQKKPEPEPQPIAEPPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDQEDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADAPNHYKKSSTPLPRH",
                "length": 522,
                "header": "tr|A0A8I5ZPV1-1|A0A8I5ZPV1_RAT Isoform 1 of TBC1 domain family, member 22a  OS=Rattus norvegicus OX=10116 GN=Tbc1d22a PE=1 SV=1 CANONICAL=A0A8I5ZPV1-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 117576971,
                "end_pos": 117292683,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000094564.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000094564.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000080048.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000080048.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5ZSU1-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1#A0A8I5ZSU1-1",
            "sequence": {
                "sequence": "MASDGARKQFWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMATESLNSEVVMETAHRVLRNHSQRQNQPSQKKPEPEPQPIAEPPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDQEDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRREILEERDFQVSNRCSEEPELGFLLGERFIKF",
                "length": 494,
                "header": "tr|A0A8I5ZSU1-1|A0A8I5ZPV1_RAT Computationally mapped isoform of TBC1 domain family, member 22a  OS=Rattus norvegicus OX=10116 GN=Tbc1d22a PE=1 SV=1 CANONICAL=A0A8I5ZPV1-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 117526696,
                "end_pos": 117292683,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000101601.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000101601.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000081731.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000081731.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AH78-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1#A0A8I6AH78-1",
            "sequence": {
                "sequence": "MASDGARKQFWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMATESLNSEVVMETAHRVLRNHSQRQNQPSQKKPEPEPQPIAEPPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDQEDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRREILEERDFQAVKSRAFPFSLHPVNLGD",
                "length": 490,
                "header": "tr|A0A8I6AH78-1|A0A8I6AH78_RAT Computationally mapped isoform of TBC1 domain family, member 22a  OS=Rattus norvegicus OX=10116 GN=Tbc1d22a PE=1 SV=1 CANONICAL=A0A8I5ZPV1-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 117573750,
                "end_pos": 117292683,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000115663.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000115663.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000087718.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000087718.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3Z994-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1#D3Z994-1",
            "sequence": {
                "sequence": "MASDGARKQFWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMATESLNSEVVMETAHRVLRNHSQRQNQPSQKKPEPEPQPIAEPPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEVRGALAGESLLMPGGWHACAWPGSRFVYFMWLIASCIFHTWFCTDQEDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQVSWQLGRLRGLRTTCHSLLGRPLGYTLLAGF",
                "length": 409,
                "header": "tr|D3Z994-1|D3Z994_RAT Computationally mapped isoform of TBC1 domain family, member 22a  OS=Rattus norvegicus OX=10116 GN=Tbc1d22a PE=1 SV=4 CANONICAL=A0A8I5ZPV1-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 117426245,
                "end_pos": 117292683,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000022945.8",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000022945.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000022945.8",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000022945.8"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "GTPase activator activity",
                        "id": "GO:0005096",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPV1",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPV1",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "14-3-3 protein binding",
                        "id": "GO:0071889",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPV1",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "activation of GTPase activity",
                        "id": "GO:0090630",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090630",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZPV1",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZPV1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 104,
            "end_pos": 106,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 374,
            "end_pos": 376,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 67,
            "end_pos": 69,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
    ]
}