{
    "uniprot_canonical_ac": "A0A0G2KB38-1",
    "uniprot_ac": "A0A0G2KB38",
    "uniprot_id": "A0A0G2KB38_RAT",
    "mass": {
        "chemical_mass": 48619.0,
        "monoisotopic_mass": 48619.0
    },
    "refseq": {
        "ac": "XP_017447114",
        "name": "speckle-type POZ protein-like isoform X1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017447114"
    },
    "gene_names": [
        {
            "name": "Spopl",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38",
            "id": "A0A0G2KB38"
        },
        {
            "name": "RGD1305847_predicted",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38",
            "id": "A0A0G2KB38"
        },
        {
            "name": "RGD1305847",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127919",
            "id": "NP_001127919"
        },
        {
            "name": "Spopl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127919",
            "id": "NP_001127919"
        },
        {
            "name": "rCG_45899",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38",
            "id": "A0A0G2KB38"
        }
    ],
    "protein_names": [
        {
            "name": "Speckle type BTB/POZ protein-like",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38#names_and_taxonomy",
            "id": "A0A0G2KB38"
        },
        {
            "name": "speckle-type POZ protein-like A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127919",
            "id": "NP_001127919"
        },
        {
            "name": "speckle-type POZ protein-like isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017447114",
            "id": "XP_017447114"
        },
        {
            "name": "speckle-type POZ protein-like",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127919",
            "id": "NP_001127919"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2KB38",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Spopl",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38",
            "locus": {
                "chromosome": "3",
                "start_pos": 471634,
                "end_pos": 401429,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000005070",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000005070"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000005070",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000005070",
            "database": "Bgee"
        },
        {
            "id": "296532",
            "url": "https://www.ncbi.nlm.nih.gov/gene/296532",
            "database": "GeneID"
        },
        {
            "id": "IPR000210",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210",
            "database": "InterPro"
        },
        {
            "id": "IPR002083",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002083",
            "database": "InterPro"
        },
        {
            "id": "IPR008974",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008974",
            "database": "InterPro"
        },
        {
            "id": "IPR011333",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333",
            "database": "InterPro"
        },
        {
            "id": "rno:296532",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296532",
            "database": "KEGG Pathway"
        },
        {
            "id": "GAVMQSD",
            "url": "https://omabrowser.org/oma/group/GAVMQSD/",
            "database": "OMA"
        },
        {
            "id": "864323at2759",
            "url": "http://www.orthodb.org/?query=864323at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00651",
            "url": "http://pfam.xfam.org/family/PF00651",
            "database": "Pfam"
        },
        {
            "id": "PF00917",
            "url": "http://pfam.xfam.org/family/PF00917",
            "database": "Pfam"
        },
        {
            "id": "R-RNO-5632684",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5632684",
            "database": "Reactome"
        },
        {
            "id": "NP_001127919",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127919",
            "database": "RefSeq"
        },
        {
            "id": "XP_017447114",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017447114",
            "database": "RefSeq"
        },
        {
            "id": "1305847",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305847",
            "database": "RGD"
        },
        {
            "id": "A0A0G2KB38",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2KB38-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5Y679",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y679",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5Y679-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y679-1",
            "database": "UniProtKB"
        },
        {
            "id": "B2RZC7",
            "url": "https://www.uniprot.org/uniprot/B2RZC7",
            "database": "UniProtKB"
        },
        {
            "id": "B2RZC7-1",
            "url": "https://www.uniprot.org/uniprot/B2RZC7-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MSREPTPPLPGDMSTSPVAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPNDKMKWCLRVNPKGLDEESRDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEHLQHCLQKRWKHCTALPKELAPPLHCKWCCRQVSVVQDSVNVSGHTNTNTLKVPECRLAEDLGNLWENTRFTDCCFFVRGKEFKAHKSVLAARSPVFNAMFEHEMEECTKNRVEINDLDPEVFKEMMRFVYTGKAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNNNQATDIMETSGWKSMIQSRPHLVAEAFRALASSQCPQFGIPRKRLKQS",
        "length": 424,
        "header": "tr|A0A0G2KB38-1|A0A0G2KB38_RAT Isoform 1 of Speckle type BTB/POZ protein-like  OS=Rattus norvegicus OX=10116 GN=Spopl PE=3 SV=1 CANONICAL=A0A0G2KB38-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2KB38-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38#A0A0G2KB38-1",
            "sequence": {
                "sequence": "MSREPTPPLPGDMSTSPVAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPNDKMKWCLRVNPKGLDEESRDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEHLQHCLQKRWKHCTALPKELAPPLHCKWCCRQVSVVQDSVNVSGHTNTNTLKVPECRLAEDLGNLWENTRFTDCCFFVRGKEFKAHKSVLAARSPVFNAMFEHEMEECTKNRVEINDLDPEVFKEMMRFVYTGKAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNNNQATDIMETSGWKSMIQSRPHLVAEAFRALASSQCPQFGIPRKRLKQS",
                "length": 424,
                "header": "tr|A0A0G2KB38-1|A0A0G2KB38_RAT Isoform 1 of Speckle type BTB/POZ protein-like  OS=Rattus norvegicus OX=10116 GN=Spopl PE=3 SV=1 CANONICAL=A0A0G2KB38-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 6108728,
                "end_pos": 6078479,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000081816.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000081816.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000075640.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075640.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5Y679-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38#A0A8I5Y679-1",
            "sequence": {
                "sequence": "MSREPTPPLPGDMSTSPVAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPNDKMKWCLRVNPKGLDEESRDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNVSGHTNTNTLKVPECRLAEDLGNLWENTRFTDCCFFVRGKEFKAHKSVLAARSPVFNAMFEHEMEECTKNRVEINDLDPEVFKEMMRFVYTGKAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINSQATDIMETSGWKSMIQSRPHLVAEAFRALASSQCPQFGIPRKRLKQS",
                "length": 374,
                "header": "tr|A0A8I5Y679-1|A0A8I5Y679_RAT Computationally mapped isoform of Speckle type BTB/POZ protein-like  OS=Rattus norvegicus OX=10116 GN=Spopl PE=3 SV=1 CANONICAL=A0A0G2KB38-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 6108728,
                "end_pos": 6078479,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000095228.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000095228.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077719.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077719.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "B2RZC7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB38#B2RZC7-1",
            "sequence": {
                "sequence": "MSREPTPPLPGDMSTSPVAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPNDKMKWCLRVNPKGLDEESRDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNVSGHTNTNTLKVPECRLAEDLGNLWENTRFTDCCFFVRGKEFKAHKSVLAARSPVFNAMFEHEMEECTKNRVEINDLDPEVFKEMMRFVYTGKAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNNNQATDIMETSGWKSMIQSRPHLVAEAFRALASSQCPQFGIPRKRLKQS",
                "length": 392,
                "header": "tr|B2RZC7-1|B2RZC7_RAT Computationally mapped isoform of Speckle type BTB/POZ protein-like  OS=Rattus norvegicus OX=10116 GN=Spopl PE=2 SV=1 CANONICAL=A0A0G2KB38-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 6108728,
                "end_pos": 6078479,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000033653.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000033653.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000035106.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000035106.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:296532",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296532",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-5632684",
            "name": "Hedgehog 'on' state",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5632684",
            "resource": "Reactome",
            "description": "Hedgehog 'on' state"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q2M2N2-1",
            "protein_name": "Speckle-type POZ protein-like",
            "gene_name": "Spopl",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSREPTPPLPGDMSTSPVAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPNDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNDKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNVSGHTSTNTLKVPECRLAEDLGNLWENTRFTDCCFFVRGKEFKAHKSVLAARSPVFNAMFEHEMEECTKNRVEINDLDPEVFKEMMRFVYTGKAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNNNQATDIMETSGWKSMIQSHPHLVAEAFRALASSQCPQFGIPRKRLKQS",
                "length": 392
            },
            "evidence": [
                {
                    "id": "41493015",
                    "url": "http://www.informatics.jax.org/homology/41493015",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q6IQ16-1",
            "protein_name": "Speckle-type POZ protein-like",
            "gene_name": "SPOPL",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLKVPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMIQSHPHLVAEAFRALASAQCPQFGIPRKRLKQS",
                "length": 392
            },
            "evidence": [
                {
                    "id": "41493015",
                    "url": "http://www.informatics.jax.org/homology/41493015",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Cul3-RING ubiquitin ligase complex",
                        "id": "GO:0031463",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "ubiquitin protein ligase binding",
                        "id": "GO:0031625",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "proteasome-mediated ubiquitin-dependent protein catabolic process",
                        "id": "GO:0043161",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of proteolysis",
                        "id": "GO:0030162",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030162",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of protein ubiquitination",
                        "id": "GO:0031397",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KB38",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB38"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 201,
            "end_pos": 203,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 328,
            "end_pos": 330,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 40,
            "end_pos": 42,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}