{
    "uniprot_canonical_ac": "A0A096MIT8-1",
    "uniprot_ac": "A0A096MIT8",
    "uniprot_id": "A0A096MIT8_RAT",
    "mass": {
        "chemical_mass": 15138.0,
        "monoisotopic_mass": 15138.0
    },
    "refseq": {
        "ac": "NP_001032442",
        "name": "protein BEX2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032442"
    },
    "gene_names": [
        {
            "name": "LOC100912195",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8",
            "id": "A0A096MIT8"
        },
        {
            "name": "Bex1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8",
            "id": "A0A096MIT8"
        },
        {
            "name": "rCG_20049",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8",
            "id": "A0A096MIT8"
        }
    ],
    "protein_names": [
        {
            "name": "Protein BEX1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8#names_and_taxonomy",
            "id": "A0A096MIT8"
        },
        {
            "name": "RCG20049",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8#names_and_taxonomy",
            "id": "A0A096MIT8"
        }
    ],
    "function": [
        {
            "annotation": "Bex family members play important roles in the formation of protein network hubs. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001032442",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032442"
                },
                {
                    "database": "PubMed",
                    "id": "25612294",
                    "url": "https://glygen.org/publication/PubMed/25612294"
                }
            ]
        },
        {
            "annotation": "Bex1 may play the neuronal anti-apoptosis role following intracerebral hemorrhage (ICH), implying a novel molecular target for the therapy of ICH.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001032442",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032442"
                },
                {
                    "database": "PubMed",
                    "id": "29572119",
                    "url": "https://glygen.org/publication/PubMed/29572119"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A096MIT8",
                    "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "LOC100912195",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8",
            "locus": {
                "chromosome": "1",
                "start_pos": 116567189,
                "end_pos": 116565790,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000033844",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000033844"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000033844",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000033844",
            "database": "Bgee"
        },
        {
            "id": "100912195",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100912195",
            "database": "GeneID"
        },
        {
            "id": "501625",
            "url": "https://www.ncbi.nlm.nih.gov/gene/501625",
            "database": "GeneID"
        },
        {
            "id": "IPR007623",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007623",
            "database": "InterPro"
        },
        {
            "id": "IPR021156",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR021156",
            "database": "InterPro"
        },
        {
            "id": "PVLQYRW",
            "url": "https://omabrowser.org/oma/group/PVLQYRW/",
            "database": "OMA"
        },
        {
            "id": "1532209at2759",
            "url": "http://www.orthodb.org/?query=1532209at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR19430",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19430",
            "database": "PANTHER"
        },
        {
            "id": "PF04538",
            "url": "http://pfam.xfam.org/family/PF04538",
            "database": "Pfam"
        },
        {
            "id": "NP_001032442",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032442",
            "database": "RefSeq"
        },
        {
            "id": "6488322",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=6488322",
            "database": "RGD"
        },
        {
            "id": "A0A096MIT8",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8",
            "database": "UniProtKB"
        },
        {
            "id": "A0A096MIT8-1",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MESKDQGAKNLNMENDHQKKEEKEEKPQDTIKREPVVAPTFEAGKNCAPRGGRRRFRVRQPISHYRWDLMHRVGEAQGRMRDENVQRFGEDMRHLMGKLRERQLSHSLRAVSTDPPHHDHNDEFCLMP",
        "length": 128,
        "header": "tr|A0A096MIT8-1|A0A096MIT8_RAT Isoform 1 of RCG20049  OS=Rattus norvegicus OX=10116 GN=LOC100912195 PE=3 SV=2 CANONICAL=A0A096MIT8-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A096MIT8-1",
            "url": "https://www.uniprot.org/uniprot/A0A096MIT8#A0A096MIT8-1",
            "sequence": {
                "sequence": "MESKDQGAKNLNMENDHQKKEEKEEKPQDTIKREPVVAPTFEAGKNCAPRGGRRRFRVRQPISHYRWDLMHRVGEAQGRMRDENVQRFGEDMRHLMGKLRERQLSHSLRAVSTDPPHHDHNDEFCLMP",
                "length": 128,
                "header": "tr|A0A096MIT8-1|A0A096MIT8_RAT Isoform 1 of RCG20049  OS=Rattus norvegicus OX=10116 GN=LOC100912195 PE=3 SV=2 CANONICAL=A0A096MIT8-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 99219606,
                "end_pos": 99219223,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000048996.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000048996.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000039471.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000039471.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs.",
            "journal": "PloS one",
            "date": "2015",
            "authors": "Fernandez EM, Diaz-Ceso MD, Vilar M",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001032442",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032442"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25612294",
                    "url": "https://glygen.org/publication/PubMed/25612294"
                }
            ]
        },
        {
            "title": "Bex1 attenuates neuronal apoptosis in rat intracerebral hemorrhage model.",
            "journal": "Pathology, research and practice",
            "date": "2018",
            "authors": "He M, Wang Y, Shen J, Duan C, Lu X, Li J",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001032442",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032442"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29572119",
                    "url": "https://glygen.org/publication/PubMed/29572119"
                }
            ]
        }
    ],
    "pathway": [],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9BXY8-1",
            "protein_name": "Protein BEX2",
            "gene_name": "BEX2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MESKEERALNNLIVENVNQENDEKDEKEQVANKGEPLALPLNVSEYCVPRGNRRRFRVRQPILQYRWDIMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP",
                "length": 128
            },
            "evidence": [
                {
                    "id": "41502486",
                    "url": "http://www.informatics.jax.org/homology/41502486",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9HBH7-1",
            "protein_name": "Protein BEX1",
            "gene_name": "BEX1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MESKEKRAVNSLSMENANQENEEKEQVANKGEPLALPLDAGEYCVPRGNRRRFRVRQPILQYRWDMMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP",
                "length": 125
            },
            "evidence": [
                {
                    "id": "41502486",
                    "url": "http://www.informatics.jax.org/homology/41502486",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9R224-1",
            "protein_name": "Protein BEX1",
            "gene_name": "Bex1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MESKDQGVKNLNMENDHQKKEEKEEKPQDTIRREPAVALTSEAGKNCAPRGGRRRFRVRQPIAHYRWDLMQRVGEPQGRMREENVQRFGGDVRQLMEKLRERQLSHSLRAVSTDPPHHDHHDEFCLMP",
                "length": 128
            },
            "evidence": [
                {
                    "id": "41502486",
                    "url": "http://www.informatics.jax.org/homology/41502486",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "signaling receptor binding",
                        "id": "GO:0005102",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MIT8",
                                "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MIT8",
                                "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MIT8",
                                "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "signal transduction",
                        "id": "GO:0007165",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MIT8",
                                "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon development",
                        "id": "GO:0061564",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MIT8",
                                "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon regeneration",
                        "id": "GO:0031103",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031103",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MIT8",
                                "url": "https://www.uniprot.org/uniprot/A0A096MIT8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}