{
    "uniprot_canonical_ac": "A0A087WPC3-1",
    "uniprot_ac": "A0A087WPC3",
    "uniprot_id": "A0A087WPC3_MOUSE",
    "mass": {
        "chemical_mass": 58594.0,
        "monoisotopic_mass": 58594.0
    },
    "refseq": {
        "ac": "NP_001093653",
        "name": "cytochrome P450, family 4, subfamily a, polypeptide 29",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093653"
    },
    "gene_names": [
        {
            "name": "Cyp4a29",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A087WPC3",
            "id": "A0A087WPC3"
        },
        {
            "name": "Cyp4a29-ps",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093653",
            "id": "NP_001093653"
        },
        {
            "name": "Cyp4a29",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093653",
            "id": "NP_001093653"
        }
    ],
    "protein_names": [
        {
            "name": "Cytochrome P450, family 4, subfamily a, polypeptide 29",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A087WPC3#names_and_taxonomy",
            "id": "A0A087WPC3"
        },
        {
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 29, pseudogene",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093653",
            "id": "NP_001093653"
        },
        {
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 29",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093653",
            "id": "NP_001093653"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:10763",
            "recommended_name": {
                "id": "DOID:10763",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10763",
                "name": "hypertension",
                "description": "An artery disease characterized by chronic elevated blood pressure in the arteries."
            },
            "synonyms": [
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "HTN",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "High blood pressure",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "hyperpiesia",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "vascular hypertensive disorder",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "10763",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10763"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A087WPC3",
                    "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Cyp4a29",
            "url": "https://www.uniprot.org/uniprot/A0A087WPC3",
            "locus": {
                "chromosome": "4",
                "start_pos": 115242084,
                "end_pos": 115254557,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000083138",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000083138"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000083138",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000083138",
            "database": "Bgee"
        },
        {
            "id": "230639",
            "url": "https://www.ncbi.nlm.nih.gov/gene/230639",
            "database": "GeneID"
        },
        {
            "id": "IPR001128",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128",
            "database": "InterPro"
        },
        {
            "id": "IPR002401",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401",
            "database": "InterPro"
        },
        {
            "id": "IPR017972",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972",
            "database": "InterPro"
        },
        {
            "id": "IPR036396",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396",
            "database": "InterPro"
        },
        {
            "id": "mmu:230639",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:230639",
            "database": "KEGG Pathway"
        },
        {
            "id": "3717143",
            "url": "http://www.informatics.jax.org/marker/MGI:3717143",
            "database": "MGI"
        },
        {
            "id": "TINIWAL",
            "url": "https://omabrowser.org/oma/group/TINIWAL/",
            "database": "OMA"
        },
        {
            "id": "1247045at2759",
            "url": "http://www.orthodb.org/?query=1247045at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00067",
            "url": "http://pfam.xfam.org/family/PF00067",
            "database": "Pfam"
        },
        {
            "id": "NP_001093653",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093653",
            "database": "RefSeq"
        },
        {
            "id": "A0A087WPC3",
            "url": "https://www.uniprot.org/uniprot/A0A087WPC3",
            "database": "UniProtKB"
        },
        {
            "id": "A0A087WPC3-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WPC3-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MSISALSPIRFLECVSGFLQVIFLIGLLLLLFKAAQHYLRRQWLLRALYQFPSPPSHWLFGHCLQFKVDEELRWILRYLEKFPGAFLHWIWGSHVFIKVCDPDYMKVILGRADPKASLYRFLTPWLGHGLFFLNGDEWFQHRRLLTPAFHYDILKPYVGIMADSVQVMLEKWEQIACQDITLEIFHPISLMMLDTIMKYAFSYQGSVQLDRSSQAYLQAVSDLNNLVTSRMKNVFLHNDIIYNLTSHSRRTNSACQIAHEHTDRVVKLRKAQLQDNKSMKKLRGKRCLDFLDILLLSRMDDGSSLSDKALRAEVDSLMFGGHDTPASGISWVFYALATHPDHQQRCREEVQSLLGDGSPITWDHLHQMPYTTMCIKEALRLYPPIPSVGRKLSTPVTFPDGRSLPKGITVLLHFYALHHNPKVWPNPEVFDPSRFAMNSVQHSHAFLPFSGGSRNCIGKHLAMNVLKVAVALTLLRFELLPDPSRVPIPTQQLVLKSKNGIYLHLRKLQ",
        "length": 509,
        "header": "tr|A0A087WPC3-1|A0A087WPC3_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 29  OS=Mus musculus OX=10090 GN=Cyp4a29 PE=3 SV=1 CANONICAL=A0A087WPC3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A087WPC3-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WPC3#A0A087WPC3-1",
            "sequence": {
                "sequence": "MSISALSPIRFLECVSGFLQVIFLIGLLLLLFKAAQHYLRRQWLLRALYQFPSPPSHWLFGHCLQFKVDEELRWILRYLEKFPGAFLHWIWGSHVFIKVCDPDYMKVILGRADPKASLYRFLTPWLGHGLFFLNGDEWFQHRRLLTPAFHYDILKPYVGIMADSVQVMLEKWEQIACQDITLEIFHPISLMMLDTIMKYAFSYQGSVQLDRSSQAYLQAVSDLNNLVTSRMKNVFLHNDIIYNLTSHSRRTNSACQIAHEHTDRVVKLRKAQLQDNKSMKKLRGKRCLDFLDILLLSRMDDGSSLSDKALRAEVDSLMFGGHDTPASGISWVFYALATHPDHQQRCREEVQSLLGDGSPITWDHLHQMPYTTMCIKEALRLYPPIPSVGRKLSTPVTFPDGRSLPKGITVLLHFYALHHNPKVWPNPEVFDPSRFAMNSVQHSHAFLPFSGGSRNCIGKHLAMNVLKVAVALTLLRFELLPDPSRVPIPTQQLVLKSKNGIYLHLRKLQ",
                "length": 509,
                "header": "tr|A0A087WPC3-1|A0A087WPC3_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 29  OS=Mus musculus OX=10090 GN=Cyp4a29 PE=3 SV=1 CANONICAL=A0A087WPC3-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 115111751,
                "end_pos": 115099281,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000118278.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000118278.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000139717.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000139717.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:230639",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:230639",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q02928-1",
            "protein_name": "Cytochrome P450 4A11",
            "gene_name": "CYP4A11",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQELQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRLPNPCEDKDQL",
                "length": 519
            },
            "evidence": [
                {
                    "id": "41499509",
                    "url": "http://www.informatics.jax.org/homology/41499509",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5TCH4-1",
            "protein_name": "Cytochrome P450 4A22",
            "gene_name": "CYP4A22",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSVSVLSPSRRLGGVSGILQVTSLLILLLLLIKAAQLYLHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQELQRIQERVKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRRLPNPCEDKDQL",
                "length": 519
            },
            "evidence": [
                {
                    "id": "41499509",
                    "url": "http://www.informatics.jax.org/homology/41499509",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "icosanoid biosynthetic process",
                        "id": "GO:0046456",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046456",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "long-chain fatty acid metabolic process",
                        "id": "GO:0001676",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "kidney development",
                        "id": "GO:0001822",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "linoleic acid metabolic process",
                        "id": "GO:0043651",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043651",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "leukotriene metabolic process",
                        "id": "GO:0006691",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006691",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "arachidonic acid metabolic process",
                        "id": "GO:0019369",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "epoxygenase P450 pathway",
                        "id": "GO:0019373",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019373",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of icosanoid secretion",
                        "id": "GO:0032305",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032305",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lauric acid metabolic process",
                        "id": "GO:0048252",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048252",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 9,
                "go_terms": [
                    {
                        "name": "iron ion binding",
                        "id": "GO:0005506",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heme binding",
                        "id": "GO:0020037",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "arachidonic acid epoxygenase activity",
                        "id": "GO:0008392",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008392",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "leukotriene-B4 20-monooxygenase activity",
                        "id": "GO:0050051",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050051",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "laurate hydroxylase activity",
                        "id": "GO:0102116",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102116",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "16-hydroxypalmitate dehydrogenase activity",
                        "id": "GO:0103002",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0103002",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "alkane 1-monooxygenase activity",
                        "id": "GO:0018685",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018685",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "arachidonic acid monooxygenase activity",
                        "id": "GO:0008391",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008391",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "long-chain fatty acid omega-hydroxylase activity",
                        "id": "GO:0102033",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102033",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "extracellular space",
                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intracellular membrane-bounded organelle",
                        "id": "GO:0043231",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "apical plasma membrane",
                        "id": "GO:0016324",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A087WPC3",
                                "url": "https://www.uniprot.org/uniprot/A0A087WPC3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 243,
            "end_pos": 245,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 276,
            "end_pos": 278,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}