{ "bcoid": "GLY_000570", "title": "Human Reactions (Rhea)", "description": "", "filename": "human_protein_reactions_rhea.csv", "filetype": "csv", "categories": { "species": "Homo sapiens", "molecule": "Protein", "tags": "Reactions Rhea", "file_type": "csv", "status": "Reviewed", "scope": "internal" }, "minitable": { "content": [ [ "10024...", "..." ], [ "10025...", "..." ] ], "headers": [ "reaction_id...", "reaction_nam..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "reaction_id" }, { "type": "string", "label": "reaction_name" }, { "type": "string", "label": "cellular_location" }, { "type": "string", "label": "pmid" }, { "type": "string", "label": "pathway_id" }, { "type": "string", "label": "equation" }, { "type": "string", "label": "reaction_summary" } ], [ "10024", "", "", "", "", "L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine", "" ], [ "10025", "", "", "", "", "L-lysyl-[histone] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine", "" ], [ "10040", "", "", "", "", "adenosine 3',5'-bisphosphate + H2O = AMP + phosphate", "" ], [ "10076", "", "", "", "", "H2O + lactose = beta-D-galactose + D-glucose", "" ], [ "10100", "", "", "", "", "a sterol ester + H2O = a fatty acid + a sterol + H(+)", "" ], [ "10101", "", "", "", "", "a sterol ester + H2O => a fatty acid + a sterol + H(+)", "" ], [ "10112", "", "", "", "", "L-homocysteine + L-serine = H2O + L,L-cystathionine", "" ], [ "10116", "", "", "", "", "6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH", "" ], [ "10120", "", "", "", "", "adenosine in double-stranded RNA + H(+) + H2O = inosine in double-stranded RNA + NH4(+)", "" ], [ "10132", "", "", "", "", "ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate", "" ], [ "10133", "", "", "", "", "ATP + benzoate + CoA => AMP + benzoyl-CoA + diphosphate", "" ], [ "10140", "", "", "", "", "NADP(+) + prostaglandin F2alpha = H(+) + NADPH + prostaglandin D2", "" ], [ "10160", "", "", "", "", "L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH", "" ], [ "10164", "", "", "", "", "(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate", "" ], [ "10180", "", "", "", "", "(6S)-10-formyltetrahydrofolate + H2O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH", "" ], [ "10188", "", "", "", "", "acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)", "" ], [ "10208", "", "", "", "", "an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = H(+) + N-terminal L-arginyl-L-amino acid-[protein] + tRNA(Arg)", "" ], [ "10216", "", "", "", "", "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase]", "" ], [ "10217", "", "", "", "", "[DNA-directed RNA polymerase] + ATP => ADP + H(+) + phospho-[DNA-directed RNA polymerase]", "" ], [ "10220", "", "", "", "", "ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)", "" ], [ "10224", "", "", "", "", "ATP + pyridoxal = ADP + H(+) + pyridoxal 5'-phosphate", "" ], [ "10244", "", "", "", "", "4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)", "" ], [ "10248", "", "", "", "", "dUTP + H2O = diphosphate + dUMP + H(+)", "" ], [ "10264", "", "", "", "", "alpha-D-glucose = beta-D-glucose", "" ], [ "10272", "", "", "", "", "a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)", "" ], [ "10273", "", "", "", "", "a 1,2-diacyl-sn-glycerol + ATP => a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)", "" ], [ "10276", "", "", "", "", "5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP", "" ], [ "10292", "", "", "", "", "acetyl-CoA + D-glucosamine 6-phosphate = CoA + H(+) + N-acetyl-D-glucosamine 6-phosphate", "" ], [ "10300", "", "", "", "", "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH", "" ], [ "10320", "", "", "", "", "trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O", "" ], [ "10336", "", "", "", "", "citrate = D-threo-isocitrate", "" ], [ "10348", "", "", "", "", "5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate + phosphate", "" ], [ "10380", "", "", "", "", "diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate", "" ], [ "10388", "", "", "", "", "GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate", "" ], [ "10389", "", "", "", "", "GTP + oxaloacetate => CO2 + GDP + phosphoenolpyruvate", "" ], [ "10390", "", "", "", "", "CO2 + GDP + phosphoenolpyruvate => GTP + oxaloacetate", "" ], [ "10412", "", "", "", "", "ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate + 2 H(+)", "" ], [ "10428", "", "", "", "", "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate", "" ], [ "10429", "", "", "", "", "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate", "" ], [ "10440", "", "", "", "", "D-glucono-1,5-lactone + H2O = D-gluconate + H(+)", "" ], [ "10488", "", "", "", "", "(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate", "" ], [ "10492", "", "", "", "", "H2O + phosphocholine = choline + phosphate", "" ], [ "10508", "", "", "", "", "D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate", "" ], [ "10580", "", "", "", "", "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate", "" ], [ "10596", "", "", "", "", "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]", "" ], [ "10597", "", "", "", "", "ATP + L-tyrosyl-[protein] => ADP + H(+) + O-phospho-L-tyrosyl-[protein]", "" ], [ "10600", "", "", "", "", "prostaglandin H2 = prostaglandin D2", "" ], [ "10656", "", "", "", "", "guanidinoacetate + S-adenosyl-L-methionine = creatine + H(+) + S-adenosyl-L-homocysteine", "" ], [ "10684", "", "", "", "", "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate", "" ], [ "10704", "", "", "", "", "ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)", "" ], [ "10716", "", "", "", "", "D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate", "" ], [ "10736", "", "", "", "", "a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH", "" ], [ "10737", "", "", "", "", "a primary alcohol + NAD(+) => an aldehyde + H(+) + NADH", "" ], [ "10738", "", "", "", "", "an aldehyde + H(+) + NADH => a primary alcohol + NAD(+)", "" ], [ "10740", "", "", "", "", "a secondary alcohol + NAD(+) = a ketone + H(+) + NADH", "" ], [ "10748", "", "", "", "", "H(+) + hydrogencarbonate = CO2 + H2O", "" ], [ "10792", "", "", "", "", "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2", "" ], [ "10832", "", "", "", "", "an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)", "" ], [ "10868", "", "", "", "", "a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA", "" ], [ "10872", "", "", "", "", "H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate", "" ], [ "10932", "", "", "", "", "ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)", "" ], [ "10944", "", "", "", "", "H2O + psi-UMP = phosphate + pseudouridine", "" ], [ "10948", "", "", "", "", "ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate + H(+)", "" ], [ "10949", "", "", "", "", "ATP + D-glucosamine => ADP + D-glucosamine 6-phosphate + H(+)", "" ], [ "10964", "", "", "", "", "ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)", "" ], [ "10980", "", "", "", "", "L-serine = D-serine", "" ], [ "10992", "", "", "", "", "glycolate + NADP(+) = glyoxylate + H(+) + NADPH", "" ], [ "11020", "", "", "", "", "1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)", "" ], [ "11028", "", "", "", "", "ATP + D-mannose = ADP + D-mannose 6-phosphate + H(+)", "" ], [ "11029", "", "", "", "", "ATP + D-mannose => ADP + D-mannose 6-phosphate + H(+)", "" ], [ "11060", "", "", "", "", "ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)", "" ], [ "11064", "", "", "", "", "beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate", "" ], [ "11068", "", "", "", "", "(5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose", "" ], [ "11092", "", "", "", "", "NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH", "" ], [ "11108", "", "", "", "", "n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate = n adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate + 2 H(+)", "" ], [ "11116", "", "", "", "", "acetyl-CoA + an alkane-alpha,omega-diamine = an N-acetylalkane-alpha,omega-diamine + CoA + H(+)", "" ], [ "11136", "", "", "", "", "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)", "" ], [ "11140", "", "", "", "", "alpha-D-mannose 1-phosphate = D-mannose 6-phosphate", "" ], [ "11148", "", "", "", "", "4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O", "" ], [ "11164", "", "", "", "", "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine", "" ], [ "11172", "", "", "", "", "(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine", "" ], [ "11180", "", "", "", "", "ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)", "" ], [ "11184", "", "", "", "", "3-(carbamoylamino)propanoate + 2 H(+) + H2O = beta-alanine + CO2 + NH4(+)", "" ], [ "11185", "", "", "", "", "3-(carbamoylamino)propanoate + 2 H(+) + H2O => beta-alanine + CO2 + NH4(+)", "" ] ] }, "readme": "Name\n - Human Reactions (Rhea)\n\nVersion\n - v-2.0.3\n\nCreated on\n - 2021-06-03T17:38:21.320871\n\nModified on\n - 2022-09-26T09:08:12.535086\n\nCreated by\n - [jeetvora@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Amanda Bell [amandab2140@gwu.edu], Jonathon Keeney [keeneyjg@gwu.edu], Millicent Quartey [mquartey@email.gwu.edu]\n\nAuthors\n - \n\nChecksum\n - \n\nExecution Domain\n Scripts\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: uniprot-proteome-homo-sapiens.nt\n URI: /data/shared/glyds/downloads/ebi/2022_05/uniprot-proteome-homo-sapiens.nt\n Output Subdomain\n Name: human_protein_reactions_rhea.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.0.3/reviewed/human_protein_reactions_rhea.csv\n Name: human_protein_reactions_rhea.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.0.3/reviewed/human_protein_reactions_rhea.stat.csv\n\nFields\n Name: \"reaction_id\"\n Description: \"The identifier assigned to a reaction in Reactome database\"\n Unique Values: \"8019\"\n Name: \"reaction_name\"\n Description: \"The name assigned to a reaction in Reactome database\"\n Unique Values: \"1\"\n Name: \"cellular_location\"\n Description: \"The loaction in the cell where reaction occurs\"\n Unique Values: \"1\"\n Name: \"pmid\"\n Description: \"NCBI PubMed database Identifier\"\n Unique Values: \"1\"\n Name: \"pathway_id\"\n Description: \"Pathway Identifier\"\n Unique Values: \"1\"\n Name: \"equation\"\n Description: \"\"\n Unique Values: \"8019\"\n Name: \"reaction_summary\"\n Description: \"\"\n Unique Values: \"1\"", "downloadurl": "/ln2data/releases/data/v-2.0.3/reviewed/human_protein_reactions_rhea.csv" }