{
    "bcoid": "GLY_000429",
    "title": "SARS-CoV1 Gene Ontology (GO)",
    "description": "The SARS coronavirus (SARS-CoV-1) Gene Ontology (GO) dataset contains sarscov1 [taxid:694009] Gene Ontology ...",
    "filename": "sarscov1_protein_go_annotation.csv",
    "filetype": "csv",
    "categories": {
        "species": "SARS coronavirus (SARS-CoV-1)",
        "molecule": "Protein",
        "tags": "Gene Ontology (Go)",
        "file_type": "csv",
        "status": "Reviewed",
        "scope": "internal"
    },
    "minitable": {
        "content": [
            [
                "P59596-1...",
                "M..."
            ],
            [
                "P59596-1...",
                "M..."
            ]
        ],
        "headers": [
            "uniprotkb_ca...",
            "gene_symbol..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "uniprotkb_canonical_ac"
                },
                {
                    "type": "string",
                    "label": "gene_symbol"
                },
                {
                    "type": "string",
                    "label": "go_term_id"
                },
                {
                    "type": "string",
                    "label": "go_term_label"
                },
                {
                    "type": "string",
                    "label": "go_term_category"
                },
                {
                    "type": "string",
                    "label": "eco_id"
                },
                {
                    "type": "string",
                    "label": "pmid"
                }
            ],
            [
                "P59596-1",
                "M",
                "GO_0019049",
                "mitigation of host antiviral defense response",
                "biological_process",
                "",
                ""
            ],
            [
                "P59596-1",
                "M",
                "GO_0016020",
                "membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59596-1",
                "M",
                "GO_0042802",
                "identical protein binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59596-1",
                "M",
                "GO_0019031",
                "viral envelope",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59596-1",
                "M",
                "GO_0055036",
                "virion membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59596-1",
                "M",
                "GO_0039660",
                "structural constituent of virion",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59596-1",
                "M",
                "GO_0044178",
                "host cell Golgi membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0016020",
                "membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0042802",
                "identical protein binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0046598",
                "positive regulation of viral entry into host cell",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0046718",
                "viral entry into host cell",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0046813",
                "receptor-mediated virion attachment to host cell",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0061025",
                "membrane fusion",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0019031",
                "viral envelope",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0039502",
                "suppression by virus of host type I interferon-mediated signaling pathway",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0019065",
                "receptor-mediated endocytosis of virus by host cell",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0019064",
                "fusion of virus membrane with host plasma membrane",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0046789",
                "host cell surface receptor binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0055036",
                "virion membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0039587",
                "suppression by virus of host tetherin activity",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0044173",
                "host cell endoplasmic reticulum-Golgi intermediate compartment membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0075509",
                "endocytosis involved in viral entry into host cell",
                "biological_process",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0020002",
                "host cell plasma membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59594-1",
                "S",
                "GO_0039654",
                "fusion of virus membrane with host endosome membrane",
                "biological_process",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0019074",
                "viral RNA genome packaging",
                "biological_process",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0060090",
                "molecular adaptor activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0003677",
                "DNA binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0003723",
                "RNA binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0005886",
                "plasma membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0042802",
                "identical protein binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0032688",
                "negative regulation of interferon-beta production",
                "biological_process",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_1990904",
                "ribonucleoprotein complex",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0019028",
                "viral capsid",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0019013",
                "viral nucleocapsid",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0044220",
                "host cell perinuclear region of cytoplasm",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0044172",
                "host cell endoplasmic reticulum-Golgi intermediate compartment",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59595-1",
                "N",
                "GO_0044177",
                "host cell Golgi apparatus",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0019082",
                "viral protein processing",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0003968",
                "RNA-dependent RNA polymerase activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0006508",
                "proteolysis",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0008242",
                "omega peptidase activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0008270",
                "zinc ion binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0016020",
                "membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0019083",
                "viral transcription",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0042802",
                "identical protein binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0046983",
                "protein dimerization activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0070536",
                "protein K63-linked deubiquitination",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0003725",
                "double-stranded RNA binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0003727",
                "single-stranded RNA binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0004519",
                "endonuclease activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0002151",
                "G-quadruplex RNA binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0016540",
                "protein autoprocessing",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0019079",
                "viral genome replication",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0004197",
                "cysteine-type endopeptidase activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0016829",
                "lyase activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039502",
                "suppression by virus of host type I interferon-mediated signaling pathway",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0004843",
                "cysteine-type deubiquitinase activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0071108",
                "protein K48-linked deubiquitination",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039520",
                "induction by virus of host autophagy",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039694",
                "viral RNA genome replication",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0044220",
                "host cell perinuclear region of cytoplasm",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0019785",
                "ISG15-specific peptidase activity",
                "molecular_function",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039657",
                "suppression by virus of host gene expression",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039519",
                "modulation by virus of host autophagy",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039548",
                "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039579",
                "suppression by virus of host ISG15-protein conjugation",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039595",
                "induction by virus of catabolism of host mRNA",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039604",
                "suppression by virus of host translation",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039648",
                "modulation by virus of host protein ubiquitination",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039690",
                "positive stranded viral RNA replication",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0030430",
                "host cell cytoplasm",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039644",
                "suppression by virus of host NF-kappaB cascade",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039714",
                "cytoplasmic viral factory",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0044165",
                "host cell endoplasmic reticulum",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0044177",
                "host cell Golgi apparatus",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039501",
                "suppression by virus of host type I interferon production",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039722",
                "suppression by virus of host toll-like receptor signaling pathway",
                "biological_process",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0044174",
                "host cell endosome",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0062243",
                "double membrane vesicle viral factory outer membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P0C6U8-1",
                "",
                "GO_0039527",
                "suppression by virus of host TRAF-mediated signal transduction",
                "biological_process",
                "",
                ""
            ],
            [
                "P59637-1",
                "E",
                "GO_0016020",
                "membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59637-1",
                "E",
                "GO_0042802",
                "identical protein binding",
                "molecular_function",
                "",
                ""
            ],
            [
                "P59637-1",
                "E",
                "GO_0055036",
                "virion membrane",
                "cellular_component",
                "",
                ""
            ],
            [
                "P59637-1",
                "E",
                "GO_0044172",
                "host cell endoplasmic reticulum-Golgi intermediate compartment",
                "cellular_component",
                "",
                ""
            ]
        ]
    },
    "readme": "Name\n   - SARS-CoV1 Gene Ontology (GO)\n\nVersion\n   - v-2.0.3\n\nCreated on\n  - 2020-04-03T11:46:41.584409\n\nModified on\n   - 2022-09-26T09:05:56.484478\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Rahi Navelkar [rsn13@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Amanda Bell [amandab2140@gwu.edu], Jonathon Keeney [keeneyjg@gwu.edu], Millicent Quartey [mquartey@email.gwu.edu]\n\nAuthors\n   - Maria Martin [martin@ebi.ac.uk], Preethi Vasudev [pvasudev@ebi.ac.uk]\n\nChecksum\n   - \n\nUsability Domain\n   - The SARS coronavirus (SARS-CoV-1) Gene Ontology (GO) dataset contains sarscov1 [taxid:694009] Gene Ontology Id and name, categories and evidence information for UniProtKB canonical accessions. The dataset is derived from 2020-01 UniProt release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen\n\nDescription Domain\n   Keywords\n   - go id\n   - go name\n   - molecular function\n   - biological process\n   - cellular component\n   - Gene Ontology (GO)\n\n   Pipeline Steps\n   - Step-1: The script extracts the GO Id, name, category and evidence from the triplestore of NT file and maps it to the UniProtKB canonical sequences.\n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: uniprot-proteome-sars-coronavirus.nt\n      URI: /data/shared/glyds/downloads/ebi/2022_05/uniprot-proteome-sars-coronavirus.nt\n   Output Subdomain\n      Name: sarscov1_protein_go_annotation.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.0.3/reviewed/sarscov1_protein_go_annotation.csv\n      Name: sarscov1_protein_go_annotation.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.0.3/reviewed/sarscov1_protein_go_annotation.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\n     Description: \"\"\n      Unique Values: \"14\"\n      Name: \"gene_symbol\"\n     Description: \"\"Official gene name/symbol assigned to the gene. Human gene names/symbols are approved by the HUGO Gene Nomenclature Committee (HGNC)\"\n      Unique Values: \"6\"\n      Name: \"go_term_id\"\n     Description: \"The Gene Ontology (GO) term unique alphanumeric identifier\"\n      Unique Values: \"120\"\n      Name: \"go_term_label\"\n     Description: \"The Gene Ontology (GO) name that is a word or string of words\"\n      Unique Values: \"120\"\n      Name: \"go_term_category\"\n     Description: \"\"The Gene Ontology (GO) domain to which the term belongs. There are three ontology domain in GO - cellular component\"\n      Unique Values: \"3\"\n      Name: \"eco_id\"\n     Description: \"Evidence & Conclusion Ontology (ECO) identifier\"\n      Unique Values: \"1\"\n      Name: \"pmid\"\n     Description: \"NCBI PubMed database Identifier\"\n      Unique Values: \"1\"",
    "downloadurl": "/ln2data/releases/data/v-2.0.3/reviewed/sarscov1_protein_go_annotation.csv"
}
