{
    "id": "A2VCK2-1.231.231",
    "start_pos": 231,
    "end_pos": 231,
    "up_seq": "LELLVPSPSLPRGCWQPPGS",
    "site_seq": "K",
    "down_seq": "SRPHRQGAQGHRAQVTQPSP",
    "uniprot_canonical_ac": "A2VCK2-1",
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCK2",
                    "url": "https://www.uniprot.org/uniprot/A2VCK2"
                }
            ],
            "common_name": "Human"
        }
    ],
    "snv": [
        {
            "evidence": [
                {
                    "id": "A2VCK2",
                    "database": "BioMuta",
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2VCK2"
                }
            ],
            "glycoeffect": [
                "o-glyco-site-loss"
            ],
            "subjects_tested": "50",
            "subjects_positive": "1",
            "frequency": "2.0",
            "sequence_org": "K",
            "sequence_mut": "E",
            "comment": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).",
            "chr_id": "1",
            "chr_pos": "32678371",
            "ref_nt": "A",
            "alt_nt": "G",
            "minor_allelic_frequency": "",
            "disease": [
                {
                    "disease_id": "DOID:1781",
                    "recommended_name": {
                        "id": "DOID:1781",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1781",
                        "name": "thyroid gland cancer",
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    },
                    "synonyms": [
                        {
                            "id": "DOID:1781",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:1781",
                            "name": "Thyroid gland neoplasm",
                            "description": ""
                        },
                        {
                            "id": "DOID:1781",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:1781",
                            "name": "malignant neoplasm of thyroid gland",
                            "description": ""
                        },
                        {
                            "id": "DOID:1781",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:1781",
                            "name": "malignant tumour of thyroid gland",
                            "description": ""
                        },
                        {
                            "id": "DOID:1781",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:1781",
                            "name": "neoplasm of thyroid gland",
                            "description": ""
                        },
                        {
                            "id": "DOID:1781",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:1781",
                            "name": "thyroid neoplasm",
                            "description": ""
                        }
                    ]
                }
            ],
            "keywords": [
                "biomuta",
                "somatic",
                "cancer",
                "disease"
            ]
        }
    ],
    "all_sites": [
        {
            "type": "snv",
            "site_list": [
                {
                    "start_pos": "231",
                    "end_pos": "231"
                }
            ]
        }
    ],
    "categories": [
        "snv_flag"
    ],
    "glycosylation": [],
    "mutagenesis": [],
    "phosphorylation": [],
    "glycation": []
}