{ "uniprot_canonical_ac": "A0A8I5ZPX3-1", "uniprot_ac": "A0A8I5ZPX3", "uniprot_id": "A0A8I5ZPX3_RAT", "mass": { "chemical_mass": 146678.0, "monoisotopic_mass": 146678.0 }, "refseq": { "ac": "NP_001102527", "name": "YEATS domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527" }, "gene_names": [ { "name": "Yeats2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3", "id": "A0A8I5ZPX3" }, { "name": "RGD1566176", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527", "id": "NP_001102527" }, { "name": "Yeats2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527", "id": "NP_001102527" } ], "protein_names": [ { "name": "YEATS domain containing 2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3#names_and_taxonomy", "id": "A0A8I5ZPX3" }, { "name": "YEATS domain-containing protein 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527", "id": "NP_001102527" } ], "function": [], "disease": [ { "disease_id": "DOID:0111693", "recommended_name": { "id": "DOID:0111693", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111693", "name": "familial adult myoclonic epilepsy 4", "description": "A familial adult myoclonic epilepsy that has_material_basis_in heterozygous mutation in YEATS2 on chromosome 3q27.1." }, "synonyms": [ { "id": "DOID:0111693", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111693", "name": "FAME4", "description": "" }, { "id": "DOID:0111693", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111693", "name": "FCMTE4", "description": "" }, { "id": "DOID:0111693", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111693", "name": "familial cortical myoclonic tremor and epilepsy 4", "description": "" }, { "id": "MONDO:0014055", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014055", "name": "FAME4", "description": "" }, { "id": "MONDO:0014055", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014055", "name": "epilepsy, familial ADULT myoclonic, 4; FAME4", "description": "" }, { "id": "MONDO:0014055", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014055", "name": "epilepsy, familial ADULT myoclonic, 4", "description": "" }, { "id": "MONDO:0014055", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014055", "name": "cortical myoclonic tremor with epilepsy, familial, 4", "description": "" }, { "id": "MONDO:0014055", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014055", "name": "FAME4", "description": "" }, { "id": "MIM:615127", "resource": "MIM", "url": "https://www.omim.org/entry/615127", "name": "Epilepsy, familial adult myoclonic, 4", "description": "Epilepsy, familial adult myoclonic, 4" } ], "evidence": [ { "id": "0111693", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0111693" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "common_name": "Rat" } ], "gene": [ { "name": "Yeats2", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3", "locus": { "chromosome": "11", "start_pos": 84583542, "end_pos": 84330064, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000023107", "url": "https://www.ensembl.org/id/ENSRNOG00000023107" } ] } } ], "crossref": [ { "id": "ENSRNOG00000023107", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000023107", "database": "Bgee" }, { "id": "498112", "url": "https://www.ncbi.nlm.nih.gov/gene/498112", "database": "GeneID" }, { "id": "IPR005033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005033", "database": "InterPro" }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro" }, { "id": "rno:498112", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:498112", "database": "KEGG Pathway" }, { "id": "XVVDVEL", "url": "https://omabrowser.org/oma/group/XVVDVEL/", "database": "OMA" }, { "id": "1482359at2759", "url": "http://www.orthodb.org/?query=1482359at2759", "database": "OrthoDB" }, { "id": "PTHR23195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23195", "database": "PANTHER" }, { "id": "PF03366", "url": "http://pfam.xfam.org/family/PF03366", "database": "Pfam" }, { "id": "NP_001102527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527", "database": "RefSeq" }, { "id": "1566176", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1566176", "database": "RGD" }, { "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3", "database": "UniProtKB" }, { "id": "A0A8I5ZPX3-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3-1", "database": "UniProtKB" }, { "id": "D3ZBV9", "url": "https://www.uniprot.org/uniprot/D3ZBV9", "database": "UniProtKB" }, { "id": "D3ZBV9-1", "url": "https://www.uniprot.org/uniprot/D3ZBV9-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MSVCHHLQAEGHWKARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDPMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNVDVEERLSSIGEQRLSRNTGRDTSSISGSHKRELRSADLAGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYVYPQSSESDISDAPPPSLTIPAPVKASPVARSPEPASAAPVGEGFPDSTEAERHSTLYSLPSSLERTPTKVTAAQKVTFSSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHLKQGSASAGISNPHAIVDKPGQATGASAPSAGSPTSKLPVASQASQGTGSPVPKIHGSSFLTSTVKQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGETPHVSTTGAANQSAFPQYVTVKGGHMIAVSPQKQVLSAGEGITQSPKIPPSKVVGVPVGSALPSTVKQAVAISSGQILVAKASSSITKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPPKTGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAAAGGSGGSCGAGGGGGGGGGAGGAPSTSGPGGGPQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTASVVQGTLGVSTSSAPGQQTLKVISGQKTTLFTQAATAGQASLLKLPDNTLKSVPAAPQLAKPGTTMLRVAGGVITAAPSPAVAFSANGAVHQAEGSAPVSSSVGSIIKTPGQPQVCVSQATMATCKATAPAAVTAASLVSAPSSISGKATVSGLLKIHSGQCSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPNPAAPSPAPVTIAKVKTEPETPGPNCVSQETQIAVKTEESSELSNYVIQVDHLETIQQLLTAVVKKIPLITAKGNDTSCFSAKSLEQYYGWNIGKRRAAEWQRAMTVRKVLQEILERNPRFHHLTALKTKHIAHWCRCHGYTPPDPESLRHNGDSIEDVLTQIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDILSLSEPLKTNIKKEQEEKQEEMRFYLPPTPGSGFVGDITQKIGITLQPVALHRNMYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRIPKEITVSNIHQAICNIPFLDFLTNKHMGRLNEDQ", "length": 1386, "header": "tr|A0A8I5ZPX3-1|A0A8I5ZPX3_RAT Isoform 1 of YEATS domain containing 2 OS=Rattus norvegicus OX=10116 GN=Yeats2 PE=4 SV=1 CANONICAL=A0A8I5ZPX3-1" }, "isoforms": [ { "isoform_ac": "A0A8I5ZPX3-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3#A0A8I5ZPX3-1", "sequence": { "sequence": "MSVCHHLQAEGHWKARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDPMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNVDVEERLSSIGEQRLSRNTGRDTSSISGSHKRELRSADLAGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYVYPQSSESDISDAPPPSLTIPAPVKASPVARSPEPASAAPVGEGFPDSTEAERHSTLYSLPSSLERTPTKVTAAQKVTFSSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHLKQGSASAGISNPHAIVDKPGQATGASAPSAGSPTSKLPVASQASQGTGSPVPKIHGSSFLTSTVKQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGETPHVSTTGAANQSAFPQYVTVKGGHMIAVSPQKQVLSAGEGITQSPKIPPSKVVGVPVGSALPSTVKQAVAISSGQILVAKASSSITKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPPKTGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAAAGGSGGSCGAGGGGGGGGGAGGAPSTSGPGGGPQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTASVVQGTLGVSTSSAPGQQTLKVISGQKTTLFTQAATAGQASLLKLPDNTLKSVPAAPQLAKPGTTMLRVAGGVITAAPSPAVAFSANGAVHQAEGSAPVSSSVGSIIKTPGQPQVCVSQATMATCKATAPAAVTAASLVSAPSSISGKATVSGLLKIHSGQCSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPNPAAPSPAPVTIAKVKTEPETPGPNCVSQETQIAVKTEESSELSNYVIQVDHLETIQQLLTAVVKKIPLITAKGNDTSCFSAKSLEQYYGWNIGKRRAAEWQRAMTVRKVLQEILERNPRFHHLTALKTKHIAHWCRCHGYTPPDPESLRHNGDSIEDVLTQIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDILSLSEPLKTNIKKEQEEKQEEMRFYLPPTPGSGFVGDITQKIGITLQPVALHRNMYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRIPKEITVSNIHQAICNIPFLDFLTNKHMGRLNEDQ", "length": 1386, "header": "tr|A0A8I5ZPX3-1|A0A8I5ZPX3_RAT Isoform 1 of YEATS domain containing 2 OS=Rattus norvegicus OX=10116 GN=Yeats2 PE=4 SV=1 CANONICAL=A0A8I5ZPX3-1" }, "locus": { "chromosome": "11", "start_pos": 80817049, "end_pos": 80744647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000112615.1", "url": "https://www.ensembl.org/id/ENSRNOT00000112615.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000080576.1", "url": "https://www.ensembl.org/id/ENSRNOP00000080576.1" } ] } }, { "isoform_ac": "D3ZBV9-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3#D3ZBV9-1", "sequence": { "sequence": "MMDKLRACIVANYYASAGLLKVSEGLKTFDPMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNVDVEERLSSIGEQRLSRNTGRDTSSISGSHKRELRSADLAGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYVYPQSSESDISDAPPPSLTIPAPVKASPVARSPEPASAAPVGEGFPDSTEAERHSTLYSLPSSLERTPTKVTAAQKVTFSSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHLKQGSASAGISNPHAIVDKPGQATGASAPSAGSPTSKLPVASQASQGTGSPVPKIHGSSFLTSTQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGETPHVSTTGAANQSAFPQYVTVKGGHMIAVSPQKQVLSAGEGITQSPKIPPSKVVGVPVGSALPSTVKQAVAISSGQILVAKASSSITKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPPKTGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAAAGGSGGSCGAGGGGGGGGGAGGAPSTSGPGGGPQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTASVVQGTLGVSTSSAPGQQTLKVISGQKTTLFTQAATAGQASLLKLPDNTLKSVPAAPQLAKPGTTMLRVAGGVITAAPSPAVAFSANGAVHQAEGSAPVSSSVGSIIKTPGQPQVCVSQATMATCKATAPAAVTAASLVSAPSSISGKATVSGLLKIHSGQCSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPNPAAPSPAPVTIAKVKTEPETPGPNCVSQETQIAVKTEESSELSNYVIQVDHLETIQQLLTAVVKKIPLITAKGNDTSCFSAKSLEQYYGWNIGKRRAAEWQRAMTVRKVLQEILERNPRFHHLTALKTKHIAHWCRCHGYTPPDPESLRHNGDSIEDVLTQIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDILSLSEPLKTNIKKEQEEKQEEMRFYLPPTPGSGFVGDITQKIGITLQPVALHRNMYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRIPKEITVSNIHQAICNIPFLDFLTNKHMGRLNEDQ", "length": 1330, "header": "tr|D3ZBV9-1|A0A8I5ZPX3_RAT Computationally mapped isoform of YEATS domain containing 2 OS=Rattus norvegicus OX=10116 GN=Yeats2 PE=4 SV=2 CANONICAL=A0A8I5ZPX3-1" }, "locus": { "chromosome": "11", "start_pos": 80813960, "end_pos": 80744647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000064212.2", "url": "https://www.ensembl.org/id/ENSRNOT00000064212.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000062371.2", "url": "https://www.ensembl.org/id/ENSRNOP00000062371.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Wang YL, Faiola F, Xu M, Pan S, Martinez E", "evidence": [ { "database": "RefSeq", "id": "NP_001102527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527" } ], "reference": [ { "type": "PubMed", "id": "18838386", "url": "https://glygen.org/publication/PubMed/18838386" } ] }, { "title": "The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.", "journal": "The EMBO journal", "date": "2010", "authors": "Orpinell M, Fournier M, Riss A, Nagy Z, Krebs AR, Frontini M, Tora L", "evidence": [ { "database": "RefSeq", "id": "NP_001102527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527" } ], "reference": [ { "type": "PubMed", "id": "20562830", "url": "https://glygen.org/publication/PubMed/20562830" } ] }, { "title": "ATAC-king the complexity of SAGA during evolution.", "journal": "Genes & development", "date": "2012", "authors": "Spedale G, Timmers HT, Pijnappel WW", "evidence": [ { "database": "RefSeq", "id": "NP_001102527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527" } ], "reference": [ { "type": "PubMed", "id": "22426530", "url": "https://glygen.org/publication/PubMed/22426530" } ] }, { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "evidence": [ { "database": "UniProtKB", "id": "D3ZBV9", "url": "https://www.uniprot.org/uniprot/D3ZBV9" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "YEATS2 is a selective histone crotonylation reader.", "journal": "Cell research", "date": "2016", "authors": "Zhao D, Guan H, Zhao S, Mi W, Wen H, Li Y, Zhao Y, Allis CD, Shi X, Li H", "evidence": [ { "database": "RefSeq", "id": "NP_001102527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102527" } ], "reference": [ { "type": "PubMed", "id": "27103431", "url": "https://glygen.org/publication/PubMed/27103431" } ] } ], "pathway": [ { "id": "rno:498112", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:498112", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3TUF7-1", "protein_name": "YEATS domain-containing protein 2", "gene_name": "Yeats2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGIKRTIKETDPDYEDVSVALPNKRHKAIESSARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDPMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNVDVEERPPSTGEQRPSRKAGRDTSSISGSHKRELRNADLTGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDSVYPQSSESDVCDAPPPTLTLPAAVKASAVAQSPEPAAAAPVGEGFPETTEAERHSTFYSLPSSLERTPTKVTTAQKVTFSSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHLKQGTASSGVSNPHVIVDKPGQVIGASTPSTGSPTSKLPVASQASQGTGSPIPKIHGSSFLTSTVKQEESLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGEAPHVSTTGAASQSAFPQYVTVKGGHMIAVSPQKQVISAGEGTTQSPKIAPSKVVGVPVGSALPSTVKQAVAISSGQILVAKASSSVTKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAAAGGSGSSGAGGGSGGGGGSGAGGTPSTSGPGGGPQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTASVVQGTLGVSSSSAQGQQTLKVISGQKTTLFTQAATAGQASLLKLPDNTLKSVPAAPQLAKPGTTMLRVAGGVITAAPSPAVAFSANGAVHQSEGSTPVSSSVGSIIKTPGQPQVCVSQATMATCKGPAAVAGTAASLVSAPSSISGKATVSGLLKVHSAQSSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTTVLPISVPNQAAPSSAPVAIAKVKTEPETPGPNCISQENQVAVKTEESSELSNYVIKVDHLETIQQLLTAVVKKIPLITAKGDDASCFSAKSLEQYYGWNIGKRRAAEWQRAMTVRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRHDGDSIEDVLTQIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDILSLSEPLKTNIKKEQEEKQEEMRFYLPPTPGSGFVGDITQKIGITLQPVALHRNMYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRIPKEITVSNIHQAICNIPFLDFLTNKHMGRLNEDQ", "length": 1407 }, "evidence": [ { "id": "41501384", "url": "http://www.informatics.jax.org/homology/41501384", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULM3-1", "protein_name": "YEATS domain-containing protein 2", "gene_name": "YEATS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGIKRTIKETDPDYEDVSVALPNKRHKAIENSARDAAVQKIETIIKEQFALEMKNKEHEIEVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPSRSSSPANQRAETPSANHSESDSLSQHNDFLSDKDNNSNMDIEERLSNNMEQRPSRNTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSLPLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQKVTFCSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTAGSVINNPYVIMDKQPGQVIGATTPSTGSPTNKISTASQVSQGTGSPVPKIHGSSFVTSTVKQEDSLFASMPPLCPIGSHPKVQSPKPITGGLGAFTKVIIKQEPGEAPHVPATGAASQSPLPQYVTVKGGHMIAVSPQKQVITPGEGIAQSAKVQPSKVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQTLKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTKTSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQSFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKSEDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQIDSEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALHRNVYASVVEDMILKATEQLVNDILRQALAVGYQTASHNRIPKEITVSNIHQAICNIPFLDFLTNKHMGILNEDQ", 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"https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "21873635" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "regulation of transcription, DNA-templated", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "negative regulation of transcription, DNA-templated", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "histone acetylation", "id": "GO:0016573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016573", "evidence": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "histone H3-K14 acetylation", "id": "GO:0044154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044154", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "regulation of histone deacetylation", "id": "GO:0031063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031063", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", 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protein binding", "id": "GO:0140030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140030", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "A0A8I5ZPX3", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ] }