{
    "uniprot_canonical_ac": "A0A286YEX9-1",
    "uniprot_ac": "A0A286YEX9",
    "uniprot_id": "SCGRX_HUMAN",
    "mass": {
        "chemical_mass": 3825.0,
        "monoisotopic_mass": 3825.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "SCYGR10",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9",
            "id": "A0A286YEX9"
        },
        {
            "name": "KRTAP28p2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9",
            "id": "A0A286YEX9"
        }
    ],
    "protein_names": [
        {
            "name": "Small cysteine and glycine repeat-containing protein 10",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9#names_and_taxonomy",
            "id": "A0A286YEX9"
        },
        {
            "name": "Keratin-associated protein 28 family pseudogene 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9#names_and_taxonomy",
            "id": "A0A286YEX9"
        }
    ],
    "function": [
        {
            "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A286YEX9",
                    "url": "https://www.uniprot.org/uniprot/A0A286YEX9#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A286YEX9",
                    "url": "https://www.uniprot.org/uniprot/A0A286YEX9"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "SCYGR10",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9",
            "locus": {
                "chromosome": "2",
                "start_pos": 227608784,
                "end_pos": 227609101,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000284622",
                        "url": "https://www.ensembl.org/id/ENSG00000284622"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000284622",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000284622",
            "database": "Bgee"
        },
        {
            "id": "A0A286YEX9",
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A286YEX9",
            "database": "BioMuta"
        },
        {
            "id": "SCYGR10",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=SCYGR10",
            "database": "GeneCards"
        },
        {
            "id": "34221",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=34221",
            "database": "HGNC"
        },
        {
            "id": "NX_A0A286YEX9",
            "url": "https://www.nextprot.org/entry/NX_A0A286YEX9",
            "database": "neXtProt"
        },
        {
            "id": "PR_A0A286YEX9",
            "url": "http://purl.obolibrary.org/obo/PR_A0A286YEX9",
            "database": "PRO"
        },
        {
            "id": "A0A286YEX9",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9",
            "database": "UniProtKB"
        },
        {
            "id": "A0A286YEX9-1",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MGCCGCGGCGGRCSGGCGGGCGGGCGGGCGGGCGGCGGGCGSYTTCR",
        "length": 47,
        "header": "sp|A0A286YEX9-1|SCGRX_HUMAN Isoform 1 of Small cysteine and glycine repeat-containing protein 10  OS=Homo sapiens OX=9606 GN=SCYGR10 PE=1 SV=1 CANONICAL=A0A286YEX9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A286YEX9-1",
            "url": "https://www.uniprot.org/uniprot/A0A286YEX9#A0A286YEX9-1",
            "sequence": {
                "sequence": "MGCCGCGGCGGRCSGGCGGGCGGGCGGGCGGGCGGCGGGCGSYTTCR",
                "length": 47,
                "header": "sp|A0A286YEX9-1|SCGRX_HUMAN Isoform 1 of Small cysteine and glycine repeat-containing protein 10  OS=Homo sapiens OX=9606 GN=SCYGR10 PE=1 SV=1 CANONICAL=A0A286YEX9-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.",
            "journal": "BMC Evol. Biol.",
            "date": "2008",
            "authors": "Zhang Y.P., Irwin D.M., Wu D.D.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A286YEX9",
                    "url": "https://www.uniprot.org/uniprot/A0A286YEX9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18721477",
                    "url": "https://glygen.org/publication/PubMed/18721477"
                }
            ]
        }
    ],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "intermediate filament",
                        "id": "GO:0005882",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A286YEX9",
                                "url": "https://www.uniprot.org/uniprot/A0A286YEX9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": []
}