{
    "uniprot_canonical_ac": "A0A1W2PS18-1",
    "uniprot_ac": "A0A1W2PS18",
    "uniprot_id": "PMIS2_HUMAN",
    "mass": {
        "chemical_mass": 15819.0,
        "monoisotopic_mass": 15819.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "PMIS2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18",
            "id": "A0A1W2PS18"
        }
    ],
    "protein_names": [
        {
            "name": "Transmembrane protein PMIS2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18#names_and_taxonomy",
            "id": "A0A1W2PS18"
        }
    ],
    "function": [
        {
            "annotation": "May play a role in spermatozoa mobility.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A1W2PS18",
                    "url": "https://www.uniprot.org/uniprot/A0A1W2PS18#function"
                },
                {
                    "database": "PubMed",
                    "id": "Q8CES1",
                    "url": "https://glygen.org/publication/PubMed/Q8CES1"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A1W2PS18",
                    "url": "https://www.uniprot.org/uniprot/A0A1W2PS18"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "PMIS2",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18",
            "locus": {
                "chromosome": "19",
                "start_pos": 35586161,
                "end_pos": 35587296,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000283758",
                        "url": "https://www.ensembl.org/id/ENSG00000283758"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000283758",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000283758",
            "database": "Bgee"
        },
        {
            "id": "A0A1W2PS18",
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A1W2PS18",
            "database": "BioMuta"
        },
        {
            "id": "PMIS2",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=PMIS2",
            "database": "GeneCards"
        },
        {
            "id": "53649",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=53649",
            "database": "HGNC"
        },
        {
            "id": "IPR007593",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007593",
            "database": "InterPro"
        },
        {
            "id": "NX_A0A1W2PS18",
            "url": "https://www.nextprot.org/entry/NX_A0A1W2PS18",
            "database": "neXtProt"
        },
        {
            "id": "EDAYINS",
            "url": "https://omabrowser.org/oma/group/EDAYINS/",
            "database": "OMA"
        },
        {
            "id": "PF04505",
            "url": "http://pfam.xfam.org/family/PF04505",
            "database": "Pfam"
        },
        {
            "id": "PR_A0A1W2PS18",
            "url": "http://purl.obolibrary.org/obo/PR_A0A1W2PS18",
            "database": "PRO"
        },
        {
            "id": "A0A1W2PS18",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18",
            "database": "UniProtKB"
        },
        {
            "id": "A0A1W2PS18-1",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A2R8YHA6",
            "url": "https://www.uniprot.org/uniprot/A0A2R8YHA6",
            "database": "UniProtKB"
        },
        {
            "id": "A0A2R8YHA6-1",
            "url": "https://www.uniprot.org/uniprot/A0A2R8YHA6-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MALKPPSATQPAPNAPATPDAPPTTGDPGASAAPGSPTTTGGPGAPAEVPQEPQEPTQTPEELAFYAPNYLCLTIFAILLFPPFGLAALYFSYEGSWTQKPTSMLPPLQTMKANQNSEWEEAYINSGRTGWFGAFVVMIGLGIIYGLVLY",
        "length": 150,
        "header": "sp|A0A1W2PS18-1|PMIS2_HUMAN Isoform 1 of Transmembrane protein PMIS2  OS=Homo sapiens OX=9606 GN=PMIS2 PE=3 SV=1 CANONICAL=A0A1W2PS18-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A1W2PS18-1",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18#A0A1W2PS18-1",
            "sequence": {
                "sequence": "MALKPPSATQPAPNAPATPDAPPTTGDPGASAAPGSPTTTGGPGAPAEVPQEPQEPTQTPEELAFYAPNYLCLTIFAILLFPPFGLAALYFSYEGSWTQKPTSMLPPLQTMKANQNSEWEEAYINSGRTGWFGAFVVMIGLGIIYGLVLY",
                "length": 150,
                "header": "sp|A0A1W2PS18-1|PMIS2_HUMAN Isoform 1 of Transmembrane protein PMIS2  OS=Homo sapiens OX=9606 GN=PMIS2 PE=3 SV=1 CANONICAL=A0A1W2PS18-1"
            },
            "locus": {
                "chromosome": "19",
                "start_pos": 35587143,
                "end_pos": 35586260,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000640449.2",
                        "url": "https://www.ensembl.org/id/ENST00000640449.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000492557.1",
                        "url": "https://www.ensembl.org/id/ENSP00000492557.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A2R8YHA6-1",
            "url": "https://www.uniprot.org/uniprot/A0A1W2PS18#A0A2R8YHA6-1",
            "sequence": {
                "sequence": "MALKPPSATQPAPNAPATPDAPPTTGDPGASAAPGSPTTTGGPGAPAEVPQEPQEPTQTPEELAFYAPNYLCLTIFAILLFPPFGLAALYFSYETMKANQNSEWEEAYINSGRTGWFGAFVVMIGLGIIYGLVLY",
                "length": 135,
                "header": "tr|A0A2R8YHA6-1|A0A2R8YHA6_HUMAN Computationally mapped isoform of Transmembrane protein PMIS2  OS=Homo sapiens OX=9606 GN=PMIS2 PE=3 SV=1 CANONICAL=A0A1W2PS18-1"
            },
            "locus": {
                "chromosome": "19",
                "start_pos": 35587143,
                "end_pos": 35586260,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000646476.1",
                        "url": "https://www.ensembl.org/id/ENST00000646476.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000496617.1",
                        "url": "https://www.ensembl.org/id/ENSP00000496617.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1W2PS18",
                                "url": "https://www.uniprot.org/uniprot/A0A1W2PS18"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "integral component of membrane",
                        "id": "GO:0016021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1W2PS18",
                                "url": "https://www.uniprot.org/uniprot/A0A1W2PS18"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intracellular membrane-bounded organelle",
                        "id": "GO:0043231",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1W2PS18",
                                "url": "https://www.uniprot.org/uniprot/A0A1W2PS18"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
    ]
}