{ "uniprot_canonical_ac": "A0A0G2KB00-1", "uniprot_ac": "A0A0G2KB00", "uniprot_id": "A0A0G2KB00_RAT", "mass": { "chemical_mass": 246852.0, "monoisotopic_mass": 246852.0 }, "refseq": {}, "gene_names": [ { "name": "Frem1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00", "id": "A0A0G2KB00" } ], "protein_names": [ { "name": "Fras1-related extracellular matrix 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00#names_and_taxonomy", "id": "A0A0G2KB00" } ], "function": [], "disease": [ { "disease_id": "DOID:0060732", "recommended_name": { "id": "DOID:0060732", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060732", "name": "chromosome 9p deletion syndrome", "description": "A chromosomal deletion syndrome characterized by trigonocephaly, flattened occiput midface hypoplasia, long philtrum, prominent forehead, broad flat nasal bridge, anteverted nares, malformed external ears, hypertelorism, hypertonia, delayed psychomotor development and that has_material_basis_in a contiguous gene deletion on the short arm of chromosome 9." }, "synonyms": [ { "id": "DOID:0060732", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060732", "name": "9p syndrome", "description": "" }, { "id": "DOID:0060732", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060732", "name": "Alfi syndrome", "description": "" }, { "id": "DOID:0060732", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060732", "name": "monosomy 9p syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "chromosome 9p deletion syndrome", "description": "Monosomy 9p is a rare chromosomal anomaly characterized by psychomotor developmental delay, facial dysmorphism (trigonocephaly, midface hypoplasia, upslanting palpebral fissures, dysplastic small ears, flat nasal bridge with anteverted nostrils and long philtrum, micrognathia, choanal atresia, short neck), single umbilical artery, omphalocele, inguinal or umbilical hernia, genital abnormalities (hypospadia, cryptorchidism), muscular hypotonia and scoliosis." }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "chromosome 9p deletion syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "9p- syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "9p syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "9p deletion syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "deletion 9p", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "monosomy 9P syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "9p deletion", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "monosomy 9p", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "9p monosomy", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "monosomy 9p syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "Alfi syndrome", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "chromosome 9p deletion", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "partial monosomy 9p", "description": "" }, { "id": "MONDO:0008013", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008013", "name": "monosomy type 9p", "description": "" } ], "evidence": [ { "id": "0060732", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060732" } ] }, { "disease_id": "DOID:0090001", "recommended_name": { "id": "DOID:0090001", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0090001", "name": "Fraser syndrome", "description": "A syndrome characterized by cryptophthalmos, syndactyly, ambiguous genitalia, laryngeal and genitourinary malformations, oral clefting, and mental retardation that has_material_basis_in homozygous or compound heterozygous mutation in the FRAS1 gene on chromosome 4q21, the FREM2 gene on chromosome 13q13, or the GRIP1 gene on chromosome 12q14." }, "synonyms": [ { "id": "DOID:0090001", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0090001", "name": "cryptophthalmos with other malformations", "description": "" }, { "id": "MONDO:0054737", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054737", "name": "Fraser syndrome 1", "description": "" }, { "id": "MONDO:0054737", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054737", "name": "FRASRS1", "description": "" }, { "id": "MONDO:0054737", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054737", "name": "cryptophthalmos-syndactyly syndrome", "description": "" }, { "id": "MONDO:0054737", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054737", "name": "cryptophthalmos with Other malformations", "description": "" }, { "id": "MONDO:0054737", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054737", "name": "Fraser syndrome", "description": "" }, { "id": "MONDO:0054737", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054737", "name": "Fraser syndrome 1; FRASRS1", "description": "" }, { "id": "MIM:219000", "resource": "MIM", "url": "https://www.omim.org/entry/219000", "name": "Fraser syndrome 1", "description": "Fraser syndrome 1" } ], "evidence": [ { "id": "0090001", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0090001" } ] }, { "disease_id": "DOID:3827", "recommended_name": { "id": "DOID:3827", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs." }, "synonyms": [ { "id": "DOID:3827", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3827", "name": "Diaphragmatic Hernia", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "diaphragmatic hernia, congenital 1", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "hernia, congenital diaphragmatic", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "diaphragmatic hernia 1", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "hemidiaphragm, agenesis of", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "diaphragm, complete agenesis of", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "diaphragm, unilateral agenesis of", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "DIH1", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "diaphragmatic hernia, congenital", "description": "" }, { "id": "MONDO:0007719", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007719", "name": "diaphragmatic defect, congenital", "description": "" }, { "id": "MONDO:0009103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009103", "name": "diaphragmatic hernia 2", "description": "" }, { "id": "MONDO:0009103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009103", "name": "diaphragmatic hernia 2; DIH2", "description": "" }, { "id": "MONDO:0009103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009103", "name": "diaphragmatic hernia 2", "description": "" }, { "id": "MONDO:0009103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009103", "name": "DIH2", "description": "" }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "diaphragmatic hernia 3", "description": "Any congenital diaphragmatic hernia in which the cause of the disease is a mutation in the ZFPM2 gene." }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "diaphragmatic hernia 3; DIH3", "description": "" }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "ZFPM2 congenital diaphragmatic hernia", "description": "" }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "congenital diaphragmatic hernia caused by mutation in ZFPM2", "description": "" }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "diaphragmatic hernia 3", "description": "" }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "diaphragmatic hernia type 3", "description": "" }, { "id": "MONDO:0012431", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012431", "name": "DIH3", "description": "" }, { "id": "MIM:610187", "resource": "MIM", "url": "https://www.omim.org/entry/610187", "name": "Diaphragmatic hernia 3", "description": "Diaphragmatic hernia 3" } ], "evidence": [ { "id": "3827", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "common_name": "Rat" } ], "gene": [ { "name": "Frem1", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00", "locus": { "chromosome": "5", "start_pos": 101166651, "end_pos": 101020448, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000022309", "url": "https://www.ensembl.org/id/ENSRNOG00000022309" } ] } } ], "crossref": [ { "id": "ENSRNOG00000022309", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000022309", "database": "Bgee" }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro" }, { "id": "IPR003644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003644", "database": "InterPro" }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro" }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro" }, { "id": "IPR032825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032825", "database": "InterPro" }, { "id": "IPR038081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038081", "database": "InterPro" }, { "id": "IPR039005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039005", "database": "InterPro" }, { "id": "IPR045658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045658", "database": "InterPro" }, { "id": "PTHR45739:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739:SF7", "database": "PANTHER" }, { "id": "PF00059", "url": "http://pfam.xfam.org/family/PF00059", "database": "Pfam" }, { "id": "PF03160", "url": "http://pfam.xfam.org/family/PF03160", "database": "Pfam" }, { "id": "PF19309", "url": "http://pfam.xfam.org/family/PF19309", "database": "Pfam" }, { "id": "1306981", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306981", "database": "RGD" }, { "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00", "database": "UniProtKB" }, { "id": "A0A0G2KB00-1", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MHSPGCTGPKALLFLLLQLLMLHLDPANATFISINRGLRVMKGSSAFLSGDHLRFAIPKEKDACRVEVVMNEPITQRVGKLIPQVFDCHFLPNEVQYVHNGCPILDEDSVKLRLYRFTETETFMETFLLRVSLVEPDCNIIRLSSNVLEVTEFYGLSQAIDKNLLQFDYDRTASLDCTIRVDPVKTQLPAHGKLVVVNRKSEGPRGDQPHSFFSESQLGAERKCPDGSCTLEPKQVTSLKVSCEDFLLTGFHYQHMQPPSPNIDYIPIQLDLTDRRSKTIYKSESAWLPVFIRVGIPNQAPRAAFMAMFVLEVDQFILTPLTTSVLDCEEDETPKPLLVFNITEAPLQGYVTHLLDHTRPISSFTWKDLSDMQVAYQPPNNSHPERRHYKMELEVYDLFFERSAPITVHISIRTADTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIGAVQLVTIGGLQHGRLTVREGKGFLFTVADLQAGVVRYHHDDSDTTKDFVAFRIFDGQHSSHHKFPINILPKDDSPPFLITNVVIELEEGKTILIQGSMLRASDMDSSDDYIFFNITKFPQAGEIMKKPGPRLIGYPVSGFLQRDLFSGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVMVHITPVDDQLPKEAPGISRHLIVKETEVAYITKKHLHFLDTESHGGELVYTITRPPCFSSSHRHLDAGKLFMVDSIPKPTKNPTAPGLNSFTQVKRFGKTLANTVSTLLGGLGLGCSNIVISVNQCICASQFASQHAVNHMKVAYMPPMQDIGPTPRHVQFTVSVSNQHGGTLHGICFNITVLPVDNQVPEVFTNTLRVAEGGQCTISTEHILVSDVDTPLDSICLSLQEMPLHGGVELDGFPLNPRGTFSWRDLHTLKVRYQHDGSEVLQDEIFLEVTDGTNSAGFVLYIEVFPVNDEPPVLKADLIPMMHCSEGGEVTITPEYIFATDADSNDSELLFLITREPRHGVVRKAGLRVDRFSQGDVISGAVAYKHTGGEIGLESCFDTVVLVVSDGEADPLVNGCCYNGPDSSVPLHKSFPTYQLNITVHPVDNQPPSIIIGRTLTVDEGFSAALTTHHLTATDWDTAPDDLEFILVSHPQFGYLENTLPSAGFEKRNTGISIASFQWRDMKASHINYVQSRHLREEPTADEFLVYATDGKQRSLETTFHVIINPTNDEAPDFVVQNITVYEGHMVELDSAIISATDRDVPKDPLLFNITHKPKHGLLLISATSKDAHNEIHNFSMELLQNGMKLAYAHDDSESSADNFVIQLSDGKHKILKTVSVSITPVNDETPTLSKKAEVSVTVGDTRVLSSAVLSAIDKDSPREKIHYLFERLPQNGQLQLKIGRDWVPLSAGMQCTQEDVDLNLLRYAHAGKMHSQDGDRFTFYLWDGDNRSPAFDCHIIIEDTGRGDIVIHAKPLVVANGDRGLLTPATLLAEDGADKAEELLYLITSPPQYGQVEYVYSPGVPITSFSQMDIAGQAVCYIHKSRTAVLSDSFRFTISNGLQTQQGVFEITLQGVDSALPVLTRNRRLRLVEGAMGLLSTDHLQLTDPDTPPENLTFFLVQLPRHGYLYLRGKVLQHNFTQQDVDSRVVAYQHAGGGAQEDCFTFLATDRKNQGFVVDGKVQKEPVLFIIQVDQLDKKAPRITRLHSPSQVGLLKNGCYGIYITSHVLKASDPDTEDDQIIFKILRGPLHGRLENTTTGEFIHEQFSQKDLSRKTILYIINPSLQVNSDILEFQAMDPTGNTAPPQRLELKWSYIEWSQTEYEVCENVGLLTLEVTRRGYSMDSAYVDIEVNQVSAVVGKDFTVTPSKLLQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTQTKAAVKILDSKGGRCHPSNSFNQSKHSTWGKGRWHPLPSGSSSLTTSGSPHLERRPPPSITKGDALRGFDLTDLSQRKMTTQGNGKSVLPSSVCRNGTDTIYNYHGIVSLKLEGDRFSAHKRKAKISVIRQPQRTVKVAELPLADKVEPTTDSNFLSQGLRPLFPKNCSVELKGLFHLEEHTHRLYQCDGIAWNVWSSQTKGLEDRSCPVGWLLHSDYCHVLVTRQKGTWATATRACREQHQGTLVTVFSRRHMQWLWAISGRKPFWIGLKNQVRTGHWEWIGGEPVAFTNWRRGPPLHPKPGKNCVLVQRRGQWQTKNCSKGKAHNFVCSRKL", "length": 2209, "header": "tr|A0A0G2KB00-1|A0A0G2KB00_RAT Isoform 1 of Fras1-related extracellular matrix 1 OS=Rattus norvegicus OX=10116 GN=Frem1 PE=3 SV=2 CANONICAL=A0A0G2KB00-1" }, "isoforms": [ { "isoform_ac": "A0A0G2KB00-1", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00#A0A0G2KB00-1", "sequence": { "sequence": "MHSPGCTGPKALLFLLLQLLMLHLDPANATFISINRGLRVMKGSSAFLSGDHLRFAIPKEKDACRVEVVMNEPITQRVGKLIPQVFDCHFLPNEVQYVHNGCPILDEDSVKLRLYRFTETETFMETFLLRVSLVEPDCNIIRLSSNVLEVTEFYGLSQAIDKNLLQFDYDRTASLDCTIRVDPVKTQLPAHGKLVVVNRKSEGPRGDQPHSFFSESQLGAERKCPDGSCTLEPKQVTSLKVSCEDFLLTGFHYQHMQPPSPNIDYIPIQLDLTDRRSKTIYKSESAWLPVFIRVGIPNQAPRAAFMAMFVLEVDQFILTPLTTSVLDCEEDETPKPLLVFNITEAPLQGYVTHLLDHTRPISSFTWKDLSDMQVAYQPPNNSHPERRHYKMELEVYDLFFERSAPITVHISIRTADTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIGAVQLVTIGGLQHGRLTVREGKGFLFTVADLQAGVVRYHHDDSDTTKDFVAFRIFDGQHSSHHKFPINILPKDDSPPFLITNVVIELEEGKTILIQGSMLRASDMDSSDDYIFFNITKFPQAGEIMKKPGPRLIGYPVSGFLQRDLFSGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVMVHITPVDDQLPKEAPGISRHLIVKETEVAYITKKHLHFLDTESHGGELVYTITRPPCFSSSHRHLDAGKLFMVDSIPKPTKNPTAPGLNSFTQVKRFGKTLANTVSTLLGGLGLGCSNIVISVNQCICASQFASQHAVNHMKVAYMPPMQDIGPTPRHVQFTVSVSNQHGGTLHGICFNITVLPVDNQVPEVFTNTLRVAEGGQCTISTEHILVSDVDTPLDSICLSLQEMPLHGGVELDGFPLNPRGTFSWRDLHTLKVRYQHDGSEVLQDEIFLEVTDGTNSAGFVLYIEVFPVNDEPPVLKADLIPMMHCSEGGEVTITPEYIFATDADSNDSELLFLITREPRHGVVRKAGLRVDRFSQGDVISGAVAYKHTGGEIGLESCFDTVVLVVSDGEADPLVNGCCYNGPDSSVPLHKSFPTYQLNITVHPVDNQPPSIIIGRTLTVDEGFSAALTTHHLTATDWDTAPDDLEFILVSHPQFGYLENTLPSAGFEKRNTGISIASFQWRDMKASHINYVQSRHLREEPTADEFLVYATDGKQRSLETTFHVIINPTNDEAPDFVVQNITVYEGHMVELDSAIISATDRDVPKDPLLFNITHKPKHGLLLISATSKDAHNEIHNFSMELLQNGMKLAYAHDDSESSADNFVIQLSDGKHKILKTVSVSITPVNDETPTLSKKAEVSVTVGDTRVLSSAVLSAIDKDSPREKIHYLFERLPQNGQLQLKIGRDWVPLSAGMQCTQEDVDLNLLRYAHAGKMHSQDGDRFTFYLWDGDNRSPAFDCHIIIEDTGRGDIVIHAKPLVVANGDRGLLTPATLLAEDGADKAEELLYLITSPPQYGQVEYVYSPGVPITSFSQMDIAGQAVCYIHKSRTAVLSDSFRFTISNGLQTQQGVFEITLQGVDSALPVLTRNRRLRLVEGAMGLLSTDHLQLTDPDTPPENLTFFLVQLPRHGYLYLRGKVLQHNFTQQDVDSRVVAYQHAGGGAQEDCFTFLATDRKNQGFVVDGKVQKEPVLFIIQVDQLDKKAPRITRLHSPSQVGLLKNGCYGIYITSHVLKASDPDTEDDQIIFKILRGPLHGRLENTTTGEFIHEQFSQKDLSRKTILYIINPSLQVNSDILEFQAMDPTGNTAPPQRLELKWSYIEWSQTEYEVCENVGLLTLEVTRRGYSMDSAYVDIEVNQVSAVVGKDFTVTPSKLLQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTQTKAAVKILDSKGGRCHPSNSFNQSKHSTWGKGRWHPLPSGSSSLTTSGSPHLERRPPPSITKGDALRGFDLTDLSQRKMTTQGNGKSVLPSSVCRNGTDTIYNYHGIVSLKLEGDRFSAHKRKAKISVIRQPQRTVKVAELPLADKVEPTTDSNFLSQGLRPLFPKNCSVELKGLFHLEEHTHRLYQCDGIAWNVWSSQTKGLEDRSCPVGWLLHSDYCHVLVTRQKGTWATATRACREQHQGTLVTVFSRRHMQWLWAISGRKPFWIGLKNQVRTGHWEWIGGEPVAFTNWRRGPPLHPKPGKNCVLVQRRGQWQTKNCSKGKAHNFVCSRKL", "length": 2209, "header": "tr|A0A0G2KB00-1|A0A0G2KB00_RAT Isoform 1 of Fras1-related extracellular matrix 1 OS=Rattus norvegicus OX=10116 GN=Frem1 PE=3 SV=2 CANONICAL=A0A0G2KB00-1" }, "locus": { "chromosome": "5", "start_pos": 97441295, "end_pos": 97323717, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000078862.2", "url": "https://www.ensembl.org/id/ENSRNOT00000078862.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075592.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075592.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "craniofacial suture morphogenesis", "id": "GO:0097094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097094", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "21873635" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "integral component of membrane", "id": "GO:0016021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "" }, { "name": "collagen-containing extracellular matrix", "id": "GO:0062023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062023", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB00", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00" } ], "pmid": "21873635" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1203, "end_pos": 1205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1234, "end_pos": 1236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1259, "end_pos": 1261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1412, "end_pos": 1414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1577, "end_pos": 1579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1601, "end_pos": 1603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1718, "end_pos": 1720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1897, "end_pos": 1899, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1971, "end_pos": 1973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2042, "end_pos": 2044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2194, "end_pos": 2196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [] }