{
    "uniprot_canonical_ac": "A0A0G2KA84-1",
    "uniprot_ac": "A0A0G2KA84",
    "uniprot_id": "A0A0G2KA84_RAT",
    "mass": {
        "chemical_mass": 112531.0,
        "monoisotopic_mass": 112531.0
    },
    "refseq": {
        "ac": "XP_006247164",
        "name": "E3 ubiquitin-protein ligase TRIM37 isoform X4",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247164"
    },
    "gene_names": [
        {
            "name": "Trim37",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84",
            "id": "A0A0G2KA84"
        },
        {
            "name": "Trim37_predicted",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84",
            "id": "A0A0G2KA84"
        },
        {
            "name": "Trim37",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247166",
            "id": "XP_006247166"
        },
        {
            "name": "rCG_34728",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84",
            "id": "A0A0G2KA84"
        }
    ],
    "protein_names": [
        {
            "name": "E3 ubiquitin-protein ligase TRIM37 isoform X4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247164",
            "id": "XP_006247164"
        },
        {
            "name": "E3 ubiquitin-protein ligase TRIM37 isoform X6",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247166",
            "id": "XP_006247166"
        },
        {
            "name": "E3 ubiquitin-protein ligase TRIM37",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101758",
            "id": "NP_001101758"
        },
        {
            "name": "Tripartite motif protein 37 (Predicted)",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84#names_and_taxonomy",
            "id": "A0A0G2KA84"
        },
        {
            "name": "Tripartite motif-containing 37",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84#names_and_taxonomy",
            "id": "A0A0G2KA84"
        },
        {
            "name": "tripartite motif protein 37",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101758",
            "id": "NP_001101758"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050436",
            "recommended_name": {
                "id": "DOID:0050436",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050436",
                "name": "mulibrey nanism",
                "description": "A syndrome that is characterized by global growth retardation of the muscle, liver, brain and eyes as well as constrictive pericarditis and has_material_basis_in mutations in the TRIM37 gene."
            },
            "synonyms": [
                {
                    "id": "DOID:0050436",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050436",
                    "name": "MUL",
                    "description": ""
                },
                {
                    "id": "DOID:0050436",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050436",
                    "name": "Mulibrey growth disorder",
                    "description": ""
                },
                {
                    "id": "DOID:0050436",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050436",
                    "name": "Muscle-Liver-Brain-Eye Nanism",
                    "description": ""
                },
                {
                    "id": "DOID:0050436",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050436",
                    "name": "PERICARDIAL CONSTRICTION AND GROWTH FAILURE",
                    "description": ""
                },
                {
                    "id": "DOID:0050436",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050436",
                    "name": "Perheentupa Syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "mulibrey nanism",
                    "description": "MULIBREY nanism (MUL) is a prenatal onset growth disorder with multiorgan manifestations."
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "pericardial constriction and growth failure",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "pericardial constriction and Growth failure",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "Perheentupa syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "mulibrey nanism",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "pericardial constriction-growth failure syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "mulibrey dwarfism",
                    "description": ""
                },
                {
                    "id": "MONDO:0009664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009664",
                    "name": "muscle-liver-brain-eye nanism",
                    "description": ""
                },
                {
                    "id": "MIM:253250",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/253250",
                    "name": "Mulibrey nanism",
                    "description": "Mulibrey nanism"
                }
            ],
            "evidence": [
                {
                    "id": "0050436",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050436"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2KA84",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Trim37",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84",
            "locus": {
                "chromosome": "10",
                "start_pos": 74436208,
                "end_pos": 74568493,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000006248",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000006248"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000006248",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000006248",
            "database": "Bgee"
        },
        {
            "id": "cd03773",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03773",
            "database": "CDD"
        },
        {
            "id": "360592",
            "url": "https://www.ncbi.nlm.nih.gov/gene/360592",
            "database": "GeneID"
        },
        {
            "id": "IPR000315",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315",
            "database": "InterPro"
        },
        {
            "id": "IPR001841",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841",
            "database": "InterPro"
        },
        {
            "id": "IPR002083",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002083",
            "database": "InterPro"
        },
        {
            "id": "IPR003649",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003649",
            "database": "InterPro"
        },
        {
            "id": "IPR008974",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008974",
            "database": "InterPro"
        },
        {
            "id": "IPR013083",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083",
            "database": "InterPro"
        },
        {
            "id": "IPR037299",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037299",
            "database": "InterPro"
        },
        {
            "id": "rno:360592",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:360592",
            "database": "KEGG Pathway"
        },
        {
            "id": "XYEYRVE",
            "url": "https://omabrowser.org/oma/group/XYEYRVE/",
            "database": "OMA"
        },
        {
            "id": "128089at2759",
            "url": "http://www.orthodb.org/?query=128089at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00643",
            "url": "http://pfam.xfam.org/family/PF00643",
            "database": "Pfam"
        },
        {
            "id": "PF00917",
            "url": "http://pfam.xfam.org/family/PF00917",
            "database": "Pfam"
        },
        {
            "id": "R-RNO-983168",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-983168",
            "database": "Reactome"
        },
        {
            "id": "NP_001101758",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101758",
            "database": "RefSeq"
        },
        {
            "id": "XP_006247164",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247164",
            "database": "RefSeq"
        },
        {
            "id": "XP_006247166",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247166",
            "database": "RefSeq"
        },
        {
            "id": "1308349",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1308349",
            "database": "RGD"
        },
        {
            "id": "A0A0G2KA84",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2KA84-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5ZJG0",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZJG0",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I5ZJG0-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZJG0-1",
            "database": "UniProtKB"
        },
        {
            "id": "B5DF77",
            "url": "https://www.uniprot.org/uniprot/B5DF77",
            "database": "UniProtKB"
        },
        {
            "id": "B5DF77-1",
            "url": "https://www.uniprot.org/uniprot/B5DF77-1",
            "database": "UniProtKB"
        },
        {
            "id": "D3ZL82",
            "url": "https://www.uniprot.org/uniprot/D3ZL82",
            "database": "UniProtKB"
        },
        {
            "id": "D3ZL82-1",
            "url": "https://www.uniprot.org/uniprot/D3ZL82-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSAEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDTPETRAKKAGSCSDMLLEGGPTSASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRAHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLADIKGSSVASADLQTNLFCADQAALATCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKKNSPKSARAIAGSLSLRRAVDSGENSRSKGDCQALSEGSPGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNVKGGRLEGMQLADLESPSDAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQPPDEDSHSSFPDGEQIDPENLHFNTDEGSGRLLVLGTQQPYCEEVQTSQPGETACTGSHGYELRPLAPANSHHQLPDV",
        "length": 1008,
        "header": "tr|A0A0G2KA84-1|A0A0G2KA84_RAT Isoform 1 of Tripartite motif-containing 37  OS=Rattus norvegicus OX=10116 GN=Trim37 PE=4 SV=2 CANONICAL=A0A0G2KA84-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2KA84-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84#A0A0G2KA84-1",
            "sequence": {
                "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSAEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDTPETRAKKAGSCSDMLLEGGPTSASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRAHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLADIKGSSVASADLQTNLFCADQAALATCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKKNSPKSARAIAGSLSLRRAVDSGENSRSKGDCQALSEGSPGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNVKGGRLEGMQLADLESPSDAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQPPDEDSHSSFPDGEQIDPENLHFNTDEGSGRLLVLGTQQPYCEEVQTSQPGETACTGSHGYELRPLAPANSHHQLPDV",
                "length": 1008,
                "header": "tr|A0A0G2KA84-1|A0A0G2KA84_RAT Isoform 1 of Tripartite motif-containing 37  OS=Rattus norvegicus OX=10116 GN=Trim37 PE=4 SV=2 CANONICAL=A0A0G2KA84-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 72075421,
                "end_pos": 71943771,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000090921.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000090921.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000075301.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075301.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5ZJG0-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84#A0A8I5ZJG0-1",
            "sequence": {
                "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSAEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDTPETRAKKAGSCSDMLLEGGPTSASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRAHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLADIKGSSVASADLQTNLFCADQAALATCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKKNSPKSARAIAGSLSLRRAVDSGENSRSKGDCQALSEGSPGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNVKGGRLEGMQLADLESPSDAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQPPDEDSHSSFPDGEQIDPENLHFNTDEGSGR",
                "length": 961,
                "header": "tr|A0A8I5ZJG0-1|A0A0G2KA84_RAT Computationally mapped isoform of Tripartite motif-containing 37  OS=Rattus norvegicus OX=10116 GN=Trim37 PE=4 SV=1 CANONICAL=A0A0G2KA84-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 72044152,
                "end_pos": 71943771,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000101990.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000101990.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077335.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077335.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "B5DF77-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84#B5DF77-1",
            "sequence": {
                "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSAEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDTPETRAKKAGSCSDMLLEGGPTSASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRAHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLADIKGSSVASADLQTNLFCADQAALATCGPENSGRLQDLGMELLAKSSVAGCYIRNRSPGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNVKGGRLEGMQLADLESPSDAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQPPDEDSHSSFPDGEQIDPENLHFNTDEGSGRLLVLGTQQPYCEEVQTSQPGETACTGSHGYELRPLAPANSHHQLPDV",
                "length": 967,
                "header": "tr|B5DF77-1|B5DF77_RAT Computationally mapped isoform of Trim37 protein  OS=Rattus norvegicus OX=10116 GN=Trim37 PE=2 SV=1 CANONICAL=A0A0G2KA84-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 72075421,
                "end_pos": 71943771,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000091163.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000091163.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000069604.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000069604.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZL82-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA84#D3ZL82-1",
            "sequence": {
                "sequence": "MFFLDSSSSLLKDIIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSAEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDTPETRAKKAGSCSDMLLEGGPTSASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRAHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLADIKGSSVASADLQTNLFCADQAALATCGPENSGRLQDLGMELLAKSSVAGCYIRNRSPGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNVKGGRLEGMQLADLESPSDAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQPPDEDSHSSFPDGEQIDPENLHFNTDEGSGRQLVSHTRRPAKCQKVPGGIVCSDLVQHWCFSGFGWHTV",
                "length": 964,
                "header": "tr|D3ZL82-1|A0A0G2KA84_RAT Computationally mapped isoform of Tripartite motif-containing 37  OS=Rattus norvegicus OX=10116 GN=Trim37 PE=4 SV=4 CANONICAL=A0A0G2KA84-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 72044571,
                "end_pos": 71946113,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000008298.7",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000008298.7"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000008299.7",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000008299.7"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:360592",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:360592",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-983168",
            "name": "Antigen processing: Ubiquitination & Proteasome degradation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-983168",
            "resource": "Reactome",
            "description": "Antigen processing: Ubiquitination & Proteasome degradation"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O94972-1",
            "protein_name": "E3 ubiquitin-protein ligase TRIM37",
            "gene_name": "TRIM37",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNPQNDTVILRFQVRSPTFFQKSRDQHWYITQLEAAQTSYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDALETRAKKSACSDMLLEGGPTTASVREAKEDEEDEEKIQNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNNMELEEGELMEDAAAAGPAGSSHGYVGSSSRISRRTHLCSAATSSLLDIDPLILIHLLDLKDRSSIENLWGLQPRPPASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKNTLSEIKSSSAASGDMQTSLFSADQAALAACGTENSGRLQDLGMELLAKSSVANCYIRNSTNKKSNSPKPARSSVAGSLSLRRAVDPGENSRSKGDCQTLSEGSPGSSQSGSRHSSPRALIHGSIGDILPKTEDRQCKALDSDAVVVAVFSGLPAVEKRRKMVTLGANAKGGHLEGLQMTDLENNSETGELQPVLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDEDTHSSFPDGEQIGPEDLSFNTDENSGR",
                "length": 964
            },
            "evidence": [
                {
                    "id": "41493657",
                    "url": "http://www.informatics.jax.org/homology/41493657",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6PCX9-1",
            "protein_name": "E3 ubiquitin-protein ligase TRIM37",
            "gene_name": "Trim37",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDSPETRTKKAGSCSDMLLEGGPTCASVRETKEDEDEEEKIQNEDYHHELSDGDLDLDLVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNSMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRTHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLSDIKGSSVASTDMQTNLFCADQAALTTCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKKNSPKSARAIAGSLSLRRAVDSGENSRSKGDCQVLAEGSSGSSQSGSRHSSPRALTHGIIGDLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNAKGGRLEGMQMADLESHSEAGEVQPTLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSMGAFNDPFLAQPPDEDSHSSFPDGEQIDPENLHFNPDEGGGR",
                "length": 961
            },
            "evidence": [
                {
                    "id": "41493657",
                    "url": "http://www.informatics.jax.org/homology/41493657",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "negative regulation of transcription by RNA polymerase II",
                        "id": "GO:0000122",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of DNA-binding transcription factor activity",
                        "id": "GO:0051091",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051091",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of NF-kappaB transcription factor activity",
                        "id": "GO:0051092",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051092",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of NF-kappaB transcription factor activity",
                        "id": "GO:0032088",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032088",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein autoubiquitination",
                        "id": "GO:0051865",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H2A monoubiquitination",
                        "id": "GO:0035518",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035518",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H2A-K119 monoubiquitination",
                        "id": "GO:0036353",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036353",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of centriole replication",
                        "id": "GO:0046600",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046600",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "aggresome assembly",
                        "id": "GO:0070842",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070842",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 8,
                "go_terms": [
                    {
                        "name": "chromatin binding",
                        "id": "GO:0003682",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transcription coactivator activity",
                        "id": "GO:0003713",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "zinc ion binding",
                        "id": "GO:0008270",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin protein ligase binding",
                        "id": "GO:0031625",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin protein ligase activity",
                        "id": "GO:0061630",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin-protein transferase activity",
                        "id": "GO:0004842",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "tumor necrosis factor receptor binding",
                        "id": "GO:0005164",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005164",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "peroxisome",
                        "id": "GO:0005777",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "aggresome",
                        "id": "GO:0016235",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016235",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ESC/E(Z) complex",
                        "id": "GO:0035098",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA84",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA84"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 285,
            "end_pos": 287,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 394,
            "end_pos": 396,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}