{
    "uniprot_canonical_ac": "A0A0G2K4P4-1",
    "uniprot_ac": "A0A0G2K4P4",
    "uniprot_id": "A0A0G2K4P4_RAT",
    "mass": {
        "chemical_mass": 64228.0,
        "monoisotopic_mass": 64228.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Bbof1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4",
            "id": "A0A0G2K4P4"
        },
        {
            "name": "Ccdc176",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4",
            "id": "A0A0G2K4P4"
        },
        {
            "name": "RGD1560978_predicted",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4",
            "id": "A0A0G2K4P4"
        },
        {
            "name": "rCG_20615",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4",
            "id": "A0A0G2K4P4"
        }
    ],
    "protein_names": [
        {
            "name": "Basal body-orientation factor 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4#names_and_taxonomy",
            "id": "A0A0G2K4P4"
        },
        {
            "name": "Coiled-coil domain-containing protein 176",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4#names_and_taxonomy",
            "id": "A0A0G2K4P4"
        }
    ],
    "function": [
        {
            "annotation": "Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I6G3Y3",
                    "url": "https://www.uniprot.org/uniprot/A0A8I6G3Y3#function"
                },
                {
                    "database": "PubMed",
                    "id": "ARBA00025007",
                    "url": "https://glygen.org/publication/PubMed/ARBA00025007"
                },
                {
                    "database": "UniProtKB",
                    "id": "D4A971",
                    "url": "https://www.uniprot.org/uniprot/D4A971#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K4P4",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K4P4",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Bbof1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4",
            "locus": {
                "chromosome": "6",
                "start_pos": 108123816,
                "end_pos": 108149607,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000011376",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000011376"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000011376",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000011376",
            "database": "Bgee"
        },
        {
            "id": "500693",
            "url": "https://www.ncbi.nlm.nih.gov/gene/500693",
            "database": "GeneID"
        },
        {
            "id": "IPR029582",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029582",
            "database": "InterPro"
        },
        {
            "id": "IPR032777",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032777",
            "database": "InterPro"
        },
        {
            "id": "rno:500693",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:500693",
            "database": "KEGG Pathway"
        },
        {
            "id": "CMTKEFE",
            "url": "https://omabrowser.org/oma/group/CMTKEFE/",
            "database": "OMA"
        },
        {
            "id": "792496at2759",
            "url": "http://www.orthodb.org/?query=792496at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR14845:SF5",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845:SF5",
            "database": "PANTHER"
        },
        {
            "id": "PF14988",
            "url": "http://pfam.xfam.org/family/PF14988",
            "database": "Pfam"
        },
        {
            "id": "NP_001128103",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128103",
            "database": "RefSeq"
        },
        {
            "id": "XP_006240410",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006240410",
            "database": "RefSeq"
        },
        {
            "id": "1560978",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1560978",
            "database": "RGD"
        },
        {
            "id": "A0A0G2K4P4",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2K4P4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I6G3Y3",
            "url": "https://www.uniprot.org/uniprot/A0A8I6G3Y3",
            "database": "UniProtKB"
        },
        {
            "id": "A0A8I6G3Y3-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6G3Y3-1",
            "database": "UniProtKB"
        },
        {
            "id": "D4A971",
            "url": "https://www.uniprot.org/uniprot/D4A971",
            "database": "UniProtKB"
        },
        {
            "id": "D4A971-1",
            "url": "https://www.uniprot.org/uniprot/D4A971-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MARRLRAPTALPEVLSSVPQQPHGGSQPSVMGSDALFWGKEVKVEDNAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLAETKEKAKEEKEKLEQKYSMQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELEDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIMILAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKAAEAQQKNSKKMEESHSCLIHQKEINDLLVKEKIMQLMQQRSQIQALQKKVVSLENALTYMTAEFEAEVSKLQQKALIENQAGLVEIDKLQQLLQMKDKEMNRIKKLARNILDERTEVEQFFLDALYEVKQQILISRKHYKQIAQAAFNLKMRMACAGRTEYPRIRTFDGREQSTNSVNQDLTEAEKWPTTQENVDIRDLTWEQKEKVLRLLFAKMNGFAARKYSQSSKPPVPDHITYDSGEMKESREEPGLPDQTFITQQVPVSDSNKMVSPGVIPQELQDSDIEPRK",
        "length": 550,
        "header": "tr|A0A0G2K4P4-1|A0A0G2K4P4_RAT Isoform 1 of Basal body-orientation factor 1  OS=Rattus norvegicus OX=10116 GN=Bbof1 PE=3 SV=2 CANONICAL=A0A0G2K4P4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K4P4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4#A0A0G2K4P4-1",
            "sequence": {
                "sequence": "MARRLRAPTALPEVLSSVPQQPHGGSQPSVMGSDALFWGKEVKVEDNAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLAETKEKAKEEKEKLEQKYSMQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELEDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIMILAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKAAEAQQKNSKKMEESHSCLIHQKEINDLLVKEKIMQLMQQRSQIQALQKKVVSLENALTYMTAEFEAEVSKLQQKALIENQAGLVEIDKLQQLLQMKDKEMNRIKKLARNILDERTEVEQFFLDALYEVKQQILISRKHYKQIAQAAFNLKMRMACAGRTEYPRIRTFDGREQSTNSVNQDLTEAEKWPTTQENVDIRDLTWEQKEKVLRLLFAKMNGFAARKYSQSSKPPVPDHITYDSGEMKESREEPGLPDQTFITQQVPVSDSNKMVSPGVIPQELQDSDIEPRK",
                "length": 550,
                "header": "tr|A0A0G2K4P4-1|A0A0G2K4P4_RAT Isoform 1 of Basal body-orientation factor 1  OS=Rattus norvegicus OX=10116 GN=Bbof1 PE=3 SV=2 CANONICAL=A0A0G2K4P4-1"
            },
            "locus": {
                "chromosome": "6",
                "start_pos": 104080566,
                "end_pos": 104057787,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000089242.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000089242.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000073122.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073122.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6G3Y3-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4#A0A8I6G3Y3-1",
            "sequence": {
                "sequence": "MPAKDKRKVKNKEQDQKKEVKVEDNAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLAETKEKAKEEKEKLEQKYSMQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELEDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIMILAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKAAEAQQKNSKKMEESHSCLIHQKEINDLLVKEKIMQLMQQRSQIQALQKKVVSLENALTYMTAEFEAEVSKLQQKALIENQAGLVEIDKLQQLLQMKDKEMNRIKKLARNILDERTEVEQFFLDALYEVKQQILISRKHYKQIAQAAFNLKMRMACAGRTEYPRIRTFDGREQSTNSVNQDLTEAEKWPTTQENVDIRDLTWEQKEKVLRLLFAKMNGFAARKYSQSSKPPVPDHITYDSGEMKESREEPGLPDQTFITQQVPVSDSNKMVSPGVIPQELQDSDIVRNLLSNQIIHHC",
                "length": 537,
                "header": "tr|A0A8I6G3Y3-1|A0A8I6G3Y3_RAT Computationally mapped isoform of Basal body-orientation factor 1  OS=Rattus norvegicus OX=10116 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A0G2K4P4-1"
            },
            "locus": {
                "chromosome": "6",
                "start_pos": 104077616,
                "end_pos": 104055393,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000098589.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000098589.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000079957.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000079957.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A971-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4#D4A971-1",
            "sequence": {
                "sequence": "MPAKDKRKVKNKEQDQKKEVKVEDNAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLAETKEKAKEEKEKLEQKYSMQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELEDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIMILAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKAAEAQQKNSKKMEESHSCLIHQKANYSRKCGY",
                "length": 271,
                "header": "tr|D4A971-1|A0A0G2K4P4_RAT Computationally mapped isoform of Basal body-orientation factor 1  OS=Rattus norvegicus OX=10116 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A0G2K4P4-1"
            },
            "locus": {
                "chromosome": "6",
                "start_pos": 104075627,
                "end_pos": 104055393,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000063900.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000063900.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000059292.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000059292.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:500693",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:500693",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q3V079-1",
            "protein_name": "Basal body-orientation factor 1",
            "gene_name": "Bbof1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MPAKDKRKDKRKDKRKGKNKGKEPKKIIKSDEPAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYNMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLAKTKEKAQEEKEKLEQKYALQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELDDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIIMLAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKEAEILQQNSKKIEENHSCLLQQKEINDLLVKEKIMQLTQQKSQIQTLQKKVVSLENALTYMTTEFEAEVLKLQQKAIIENQAGLVEIDKLQQLLQMKDREMNRVKRLAKNILDERTEVEQFFLDALYEVKQQILASRKHYKQIAQAAFNLKMRAACAGKTEYPRIRTFDGKEQSTNSVNQDLLEAEKWPTTQKNVDIRDLTWEQKEKVLRLLFAKMNGFAARKYSQSSKPPVPDHIIYGSGEMKETGDENNLLDQTFITQQAPVSDSNRMVSPDVIPQGLQDSDIA",
                "length": 533
            },
            "evidence": [
                {
                    "id": "41501831",
                    "url": "http://www.informatics.jax.org/homology/41501831",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8ND07-1",
            "protein_name": "Basal body-orientation factor 1",
            "gene_name": "BBOF1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSDSGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF",
                "length": 529
            },
            "evidence": [
                {
                    "id": "41501831",
                    "url": "http://www.informatics.jax.org/homology/41501831",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K4P4",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ciliary basal body",
                        "id": "GO:0036064",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K4P4",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K4P4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 55,
            "end_pos": 57,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}